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STERISHEALTHCARE 573431969ec6680ff811d9bc Products https://www.sterisindia.com
Home Products sacubitril 49mg and valsartan 51mg tablets
SACUBRIGHT 100 Sacu
SACUBRIGHT 100 Sacu
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CARDIOLOGYRANGE by SACUBRIGHT 100

sacubitril 49mg and valsartan 51mg tablets

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SACUBRIGHT 100 Sacubitril 49mg, Valsartan 51mg SACUBRIGHT 100 is a combination medication containing Sacubitril 49 mg and Valsartan 51 mg, formulated to support patients diagnosed with certain types of chronic heart failure. This dual-ingredient therapy belongs to a class of medicines known as angiotensin receptor neprilysin inhibitors (ARNIs). It is specifically designed to improve heart function, reduce strain on the cardiovascular system, and lower the risk of hospitalization related to heart failure. Heart failure is a long-term condition in which the heart is unable to pump blood efficiently enough to meet the body’s needs. SACUBRIGHT 100 works through two complementary mechanisms to enhance cardiovascular performance and promote better long-term outcomes when used under medical supervision. This strength (100 mg total combination dose) is typically prescribed as part of a titration schedule, where dosage may be gradually increased based on patient tolerance and clinical response. How SACUBRIGHT 100 Works SACUBRIGHT 100 combines two active ingredients that target different pathways involved in heart failure: 1. Sacubitril (Neprilysin Inhibitor) Sacubitril blocks the enzyme neprilysin, which is responsible for breaking down beneficial peptides in the body. By inhibiting this enzyme, sacubitril increases levels of natural substances that: Relax blood vessels Reduce sodium retention Decrease fluid buildup Lower blood pressure This helps reduce the workload on the heart. 2. Valsartan (Angiotensin II Receptor Blocker – ARB) Valsartan blocks the action of angiotensin II, a hormone that causes blood vessels to constrict and increases blood pressure. By blocking this hormone, valsartan: Dilates blood vessels Reduces blood pressure Decreases strain on the heart Prevents harmful heart remodeling Together, these two components provide a comprehensive approach to managing heart failure by improving circulation and reducing stress on the heart muscle. Uses of SACUBRIGHT 100 SACUBRIGHT 100 is primarily prescribed for: 1. Chronic Heart Failure with Reduced Ejection Fraction (HFrEF) It is indicated for patients whose heart pumping capacity is reduced. The medication helps: Improve heart efficiency Reduce symptoms such as shortness of breath and fatigue Lower the risk of hospitalization Improve overall survival in eligible patients 2. Cardiovascular Risk Reduction In certain patients, SACUBRIGHT 100 may reduce the risk of cardiovascular-related death when used as part of a comprehensive heart failure management plan. Key Benefits of SACUBRIGHT 100 1. Improved Heart Function By supporting both vasodilation and fluid balance, SACUBRIGHT 100 helps the heart pump more effectively. 2. Reduced Hospitalizations Clinical use of sacubitril and valsartan combination therapy has been associated with a lower rate of hospital admissions due to worsening heart failure. 3. Lower Cardiovascular Mortality Risk Appropriate use may reduce the risk of heart-related death in patients with chronic heart failure. 4. Dual Mechanism Advantage Unlike traditional single-mechanism therapies, SACUBRIGHT 100 works through two pathways, offering broader cardiovascular support. 5. Enhanced Quality of Life Patients may experience improvements in: Exercise tolerance Energy levels Breathing comfort Overall daily functioning 6. Structured Dose Flexibility The 100 mg combination strength allows healthcare providers to adjust therapy progressively based on patient response and tolerability. Dosage and Administration SACUBRIGHT 100 should be taken exactly as prescribed by a healthcare professional. It is usually taken twice daily. Tablets may be taken with or without food. Do not stop or change dosage without consulting your doctor. Before starting SACUBRIGHT 100, patients may need to discontinue ACE inhibitors for a specified period to reduce the risk of complications. Regular monitoring of blood pressure, kidney function, and potassium levels is typically recommended during treatment. Possible Side Effects of SACUBRIGHT 100 Like all medications, SACUBRIGHT 100 may cause side effects. Many are manageable and improve over time. Common Side Effects Low blood pressure (hypotension) Dizziness Fatigue Increased potassium levels (hyperkalemia) Mild kidney function changes Patients may feel lightheaded, especially when standing up quickly. Kidney-Related Effects Monitoring is important as the medication may affect kidney function in some individuals, particularly those with pre-existing kidney disease. Electrolyte Imbalance Elevated potassium levels may occur, which can cause: Muscle weakness Irregular heartbeat Numbness or tingling Routine blood tests help detect and manage this risk. Rare but Serious Side Effects Seek immediate medical attention if you experience: Swelling of face, lips, or throat (angioedema) Severe allergic reactions Persistent fainting Severe decrease in urine output Angioedema is rare but potentially serious and requires urgent care. Precautions and Warnings Not recommended during pregnancy due to risk of fetal harm. Breastfeeding mothers should consult a healthcare provider before use. Patients with severe liver impairment should use caution. Avoid potassium supplements or salt substitutes unless advised by a doctor. Inform your physician about all medications being taken to avoid interactions. SACUBRIGHT 100 should not be used together with ACE inhibitors or certain other medications without proper medical guidance. Who Should Avoid SACUBRIGHT 100? This medication may not be suitable for individuals who: Have a history of angioedema related to ACE inhibitors or ARBs Are pregnant Have severe liver dysfunction Are unable to tolerate ARB therapy A full medical evaluation is essential before starting treatment. Storage Instructions Store at room temperature. Keep away from moisture and direct sunlight. Keep out of reach of children. Do not use after the expiration date printed on the packaging. Conclusion SACUBRIGHT 100 (Sacubitril 49 mg + Valsartan 51 mg) represents an advanced therapeutic approach in the management of chronic heart failure with reduced ejection fraction. By combining neprilysin inhibition with angiotensin receptor blockade, it delivers comprehensive cardiovascular protection and helps reduce the strain placed on the heart.

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Brand Name :SACUBRIGHT 100
Manufactured By :Steris Healthcare Pvt Ltd
Package SIZE :For 14 tablet
Storage :Store In A Cool & Dry Place
country :INDIA

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