Description
Product details
ZOLMIGRAN is a powerful intravenous medication containing Zoledronic Acid 5mg, designed to treat and prevent bone-related complications in various conditions such as osteoporosis, Paget’s disease of bone, and cancers that affect bones. It belongs to a class of drugs known as bisphosphonates, which help in strengthening bones, reducing bone loss, and preventing fractures. ZOLMIGRAN is often recommended when oral treatments are ineffective or not well-tolerated. Key Ingredients Zoledronic Acid (5mg): The active pharmaceutical ingredient responsible for inhibiting bone resorption and maintaining bone density. Key Benefits Helps in the treatment of osteoporosis in postmenopausal women and men at high risk of fractures. Effective in treating Paget's disease of bone, promoting normal bone formation. Reduces the risk of bone fractures in patients with cancer that has spread to bones. Prevents skeletal-related events (SREs) like bone pain, fractures, and spinal cord compression in metastatic bone diseases. Offers a once-yearly infusion for osteoporosis, improving patient compliance. How Does It Work? ZOLMIGRAN works by binding strongly to the bone surface, specifically at sites of active resorption. Zoledronic Acid inhibits the activity of osteoclasts, the cells responsible for breaking down bone tissue. By reducing osteoclast activity, it slows down the process of bone resorption, leading to increased bone mass and strength. This action helps in stabilizing bone structure, reducing the likelihood of fractures and other bone complications. Directions for Use ZOLMIGRAN is administered as an intravenous infusion by a healthcare professional. The usual dosage for osteoporosis is a single 5mg infusion once a year. For Paget's disease of bone, a single 5mg infusion is typically sufficient. Adequate hydration before and after the infusion is recommended. Calcium and vitamin D supplementation may be prescribed to support bone health. Follow your doctor’s specific instructions regarding dosage and frequency. Side Effects Common side effects include flu-like symptoms such as fever, chills, muscle pain, and joint pain after infusion. May cause headache, fatigue, and nausea. Can lead to low blood calcium levels (hypocalcemia), which may require supplementation. Possible kidney function impairment, especially in patients with pre-existing conditions. Rarely, osteonecrosis of the jaw (ONJ) and atypical femur fractures can occur with long-term use. Always inform your doctor of any side effects experienced post-infusion.
![TELAVINCE AF 25 is primarily indicated for:
Hypertension (High Blood Pressure): Effectively helps in lowering elevated blood pressure.
Cardiovascular Risk Reduction: Supports heart health and reduces the risk of heart attack, stroke, and other complications related to high blood pressure.
Patients requiring combination therapy: Ideal for individuals who need more than one antihypertensive agent for optimal blood pressure control.
Mechanism of Action:
TELAVINCE AF 25 combines two mechanisms for effective blood pressure management:
Telmisartan: Blocks angiotensin II receptors, preventing blood vessel constriction and thereby reducing blood pressure.
[AF Component, e.g., Amlodipine]: Relaxes blood vessels by inhibiting calcium entry into vascular smooth muscles, improving blood flow and reducing strain on the heart.
This dual-action combination provides better efficacy than single-drug therapy while maintaining a favorable safety profile.
Dosage and Administration:
Recommended Dose: As prescribed by a healthcare professional, typically one tablet daily.
Route: Oral, with water.
Timing: Can be taken with or without food, preferably at the same time each day.
Adjustment: Dose may be adjusted based on individual response and tolerability.
Important: Always follow your doctor’s instructions. Do not change the dose or stop medication without medical advice.
Key Benefits of TELAVINCE AF 25:
Effective blood pressure control with dual-action therapy.
Reduces the risk of cardiovascular complications associated with hypertension.
Convenient once-daily dosing for better patient adherence.
Well-tolerated with minimal side effects.
Suitable for long-term use under medical supervision.
Safety and Precautions:
Inform your doctor if you have kidney disease, liver disease, or heart failure.
Pregnant or breastfeeding women should use only if recommended by a physician.
Avoid excessive use of potassium-containing salt substitutes.
Regular monitoring of blood pressure and kidney function is recommended.
Do not combine with other angiotensin receptor blockers (ARBs) unless prescribed.
Possible Side Effects:
While generally well-tolerated, some patients may experience:
Dizziness or lightheadedness
Fatigue or weakness
Mild swelling of ankles or feet
Nausea or headache
Seek immediate medical attention if you experience:
Severe allergic reactions
Swelling of face, lips, or throat
Difficulty breathing
Storage Instructions:
Store in a cool, dry place away from sunlight.
Keep out of reach of children and pets.
Do not use after the expiry date mentioned on the package.
Why Choose TELAVINCE AF 25:
Developed by Steris Healthcare Pvt. Ltd, a trusted pharmaceutical company.
Ensures quality, safety, and efficacy in every tablet.
Designed for patient convenience with once-daily dosing.
Backed by clinical research for effective hypertension management.
Disclaimer:
The information provided here is for educational purposes only. TELAVINCE AF 25 should be used only under medical supervision. Consult your healthcare provider for personalized advice. Side effects may vary from person to person.](https://productimages.withfloats.com/tile/68e63e0d931b4d6a7310ae2a.png)
![TELAVINCE EM is primarily indicated for the management of:
Hypertension (High Blood Pressure): Helps in reducing elevated blood pressure effectively.
Cardiovascular Risk Reduction: Supports heart health and reduces the risk of stroke, heart attack, and related complications.
Patients requiring combination therapy: Suitable for individuals who need more than one antihypertensive for better blood pressure control.
Mechanism of Action:
TELAVINCE EM works through a dual mechanism to control blood pressure:
Telmisartan: Blocks angiotensin II receptors, preventing blood vessel constriction and reducing blood pressure.
[EM Component, e.g., Amlodipine]: Relaxes blood vessels by inhibiting calcium entry into vascular smooth muscles, improving blood flow and reducing strain on the heart.
The combination ensures better efficacy than monotherapy while maintaining a favorable safety profile.
Dosage and Administration:
Recommended Dose: As prescribed by a healthcare professional, typically one tablet daily.
Route: Oral administration with water.
Timing: Can be taken with or without food, preferably at the same time each day.
Adjustment: Dose may be modified based on individual response and tolerability.
Important: Always follow your doctor’s instructions. Do not alter the dose or stop medication without medical advice.
Key Benefits of TELAVINCE EM:
Effective blood pressure control with dual-action therapy.
Reduces risk of cardiovascular events associated with hypertension.
Convenient once-daily dosing improves patient compliance.
Well-tolerated with a low incidence of side effects.
Suitable for long-term use under medical supervision.
Safety and Precautions:
Inform your doctor if you have kidney disease, liver disease, or heart failure.
Pregnant or breastfeeding women should avoid use unless advised by a physician.
Avoid excessive salt substitutes containing potassium.
Regular blood pressure and kidney function monitoring is recommended.
Do not use in combination with other angiotensin receptor blockers (ARBs) unless prescribed.
Possible Side Effects:
Although TELAVINCE EM is generally well-tolerated, some patients may experience:
Dizziness or lightheadedness
Fatigue or weakness
Mild swelling in ankles or feet
Nausea or headache
Seek immediate medical attention if you experience severe side effects such as difficulty breathing, swelling of face or throat, or severe allergic reactions.
Storage Instructions:
Store in a cool, dry place away from direct sunlight.
Keep out of reach of children and pets.
Do not use after the expiry date mentioned on the package.
Why Choose TELAVINCE EM:
Developed by Steris Healthcare Pvt. Ltd, a trusted name in pharmaceutical excellence.
Ensures quality, safety, and efficacy in every tablet.
Designed for optimal patient compliance with convenient dosing.
Backed by clinical research for managing hypertension effectively.
Disclaimer:
The information provided here is intended for educational purposes only. TELAVINCE EM should be used only under medical supervision. Consult your healthcare provider for personalized advice. Side effects may vary from person to person.](https://productimages.withfloats.com/tile/68e63c1a4302b5c8207e2858.png)
