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ST-GLIPTIN M 100/1000 is an advanced oral antidiabetic medication designed for the effective management of Type 2 Diabetes Mellitus. This powerful combination of Sitagliptin (100 mg) and Metformin Hydrochloride (1000 mg) offers dual action in controlling elevated blood glucose levels, especially in patients who do not respond adequately to metformin or sitagliptin alone. It is intended for adults and is generally used in conjunction with diet and exercise to enhance glycemic control. Key Ingredients Sitagliptin (100 mg) Sitagliptin is a DPP-4 (Dipeptidyl Peptidase-4) inhibitor that increases the levels of incretin hormones, which help regulate blood sugar by increasing insulin release and decreasing glucagon levels. Metformin Hydrochloride (1000 mg) Metformin belongs to the biguanide class of antidiabetics. It works by reducing the amount of sugar produced by the liver and improves the body’s sensitivity to insulin, facilitating better glucose utilization. Key Benefits Helps reduce both fasting and postprandial (after-meal) blood glucose levels effectively Improves overall glycemic control in patients with Type 2 diabetes Combines two different mechanisms of action for better diabetes management Minimizes the risk of hypoglycemia compared to other antidiabetic therapies May support weight neutrality or slight weight loss in diabetic individuals How Does It Work? ST-GLIPTIN M 100/1000 works through a synergistic mechanism by combining two effective antidiabetic agents: Sitagliptin enhances the levels of incretin hormones, which help the pancreas produce more insulin and reduce the secretion of glucagon, especially when blood sugar is high. Metformin reduces hepatic glucose production and increases insulin sensitivity, which helps the body use glucose more efficiently. Together, these agents provide comprehensive blood sugar control by addressing multiple physiological pathways involved in glucose metabolism. Directions for Use Take ST-GLIPTIN M 100/1000 exactly as prescribed by your physician. It is typically taken once or twice daily with meals to reduce gastrointestinal side effects and optimize absorption. Swallow the tablet whole with water. Do not crush or chew the tablet. Maintain a balanced diet and follow an active lifestyle for best results. Regular blood sugar monitoring is essential to assess effectiveness and make any necessary dosage adjustments. Side Effects Common side effects may include nausea, diarrhea, stomach upset, or headache. Some individuals may experience respiratory tract infections, sore throat, or a runny nose. Lactic acidosis is a rare but serious side effect associated with high-dose metformin—seek immediate medical attention if symptoms like unusual fatigue, muscle pain, difficulty breathing, or abdominal discomfort occur. Allergic reactions such as rash, itching, or swelling are uncommon but possible. Always inform your doctor of any persistent or bothersome side effects for timely intervention.