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{ "products": [ { "_id": "69e9f8f5051af90911258c1b", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "nebivolol 5mg cilnidipine 10mg", "description": "Nebivolol 5mg + Cilnidipine 10mg Tablets—Complete Guide\nA fixed-dose combination antihypertensive for effective blood pressure control. Understand how it works, who it's for, dosage, and safety before you buy.\n\nDrug Class\nBeta-blocker + Calcium Channel Blocker\nStrength\nNebivolol 5mg / Cilnidipine 10mg\nRoute\nOral (tablet)\nSchedule\nRx Only\nWhat is this combination?\nUnderstanding nebivolol 5mg + cilnidipine 10mg\nNebivolol 5mg + cilnidipine 10mg is a fixed-dose combination tablet prescribed for the management of hypertension (high blood pressure) in adults. It pairs two complementary mechanisms into one convenient pill, making it a popular choice when single-drug therapy proves insufficient for adequate blood pressure control.\n\nThis combination is widely preferred by cardiologists when patients need better BP reduction with fewer pills, improved tolerability, and protection of vital organs such as the heart and kidneys. If your doctor has prescribed this tablet, you're likely being treated for stage 1 or stage 2 hypertension, with or without associated cardiovascular risk factors.\n\nThis is not an over-the-counter product. Always use nebivolol + cilnidipine tablets only under the supervision of a licensed physician. Self-medication or dose changes without medical advice can be dangerous.\nHow it works\nMechanism of action — dual-pathway blood pressure control\nThe effectiveness of this combination lies in how its two active ingredients target blood pressure through different pathways simultaneously:\n\nNebivolol 5mg\nA third-generation cardioselective beta-1 blocker. It slows the heart rate, reduces the force of cardiac contraction, and lowers cardiac output. Uniquely, nebivolol also releases nitric oxide, causing blood vessel relaxation — a property not seen in older beta-blockers. This makes it better tolerated and less likely to cause sexual dysfunction or cold extremities.\nCilnidipine 10mg\nAn N/L-type calcium channel blocker. Unlike conventional CCBs (e.g., amlodipine), cilnidipine blocks both L-type and N-type calcium channels. N-type blockade in the sympathetic nervous system reduces norepinephrine release, leading to smoother, more sustained BP reduction with significantly less ankle swelling — a common complaint with older CCBs.\nTogether, these agents provide additive antihypertensive effect while offsetting each other's side effects. Nebivolol reduces tachycardia that CCBs can sometimes cause, while cilnidipine's vasodilatory effect complements nebivolol's cardiac output reduction.\n\nIndications\nWho is Nebivolol 5 mg and Cilnidipine 10 mg prescribed for?\nThis combination is indicated for adults with hypertension who are not adequately controlled on monotherapy. It is especially suited for patients who have:\n\nCondition:\tWhy this combination is preferred\nHypertension with high heart rate\tNebivolol slows heart rate while cilnidipine controls peripheral resistance\nHypertension with diabetes\tMetabolically neutral; does not worsen glucose tolerance or lipid profile\nHypertension with CKD / proteinuria:\tCilnidipine's N-type blockade reduces glomerular pressure and protein leakage\nHypertension with coronary artery disease\tNebivolol provides cardioprotection and anti-anginal effect\nAmlodipine-related ankle edema\tSwitching to cilnidipine substantially reduces pedal edema due to N-type blockade\nUncontrolled BP on single antihypertensive\tCombination adds complementary mechanisms without increasing pill burden\n\nosage & Administration\nHow to take nebivolol 5 mg + cilnidipine 10mg\nThe standard recommended dose is one tablet once daily, preferably at the same time each day — most commonly in the morning with or without food. Your physician may adjust the dose based on your blood pressure response and individual tolerability.\n\nDo not crush, chew, or split the tablet unless your doctor advises. If you miss a dose, take it as soon as you remember, but skip it if it is almost time for the next dose. Never double up on doses. Swallowing the tablet whole with water is the preferred method of administration.\n\nDo not stop taking this medication abruptly. Sudden discontinuation of nebivolol (a beta-blocker) can trigger rebound hypertension or even angina in patients with underlying coronary disease. Always taper under medical guidance.\n\nCommon and serious side effects to know\nLike all medicines, nebivolol + cilnidipine can cause side effects, though not everyone experiences them. Knowing what to watch for helps you respond promptly.\n\nSide effect\tFrequency\tWhat to do\nHeadache, dizziness\tCommon (early phase)\tUsually resolves in 1–2 weeks; avoid sudden posture changes\nFatigue, tiredness\tCommon\tMonitor; often improves after dose adjustment\nAnkle swelling (pedal edema)\tLess common than with amlodipine\tReport if worsening; may require dose review\nBradycardia (slow heart rate)\tUncommon\tSeek medical advice if heart rate <50 bpm\nNausea, stomach upset\tUncommon\tTake after meals to minimise\nBronchospasm\tRare\tStop immediately; seek emergency care if breathlessness\nSevere hypotension\tRare\tEmergency — seek immediate medical attention.\n\nWhen should this combination not be used?\nImportant safety information\nThis tablet is contraindicated in: cardiogenic shock, decompensated heart failure, severe bradycardia (<60 bpm), sick sinus syndrome, second- or third-degree AV block (without pacemaker), severe hepatic impairment, known hypersensitivity to nebivolol or cilnidipine, pregnancy, and breastfeeding.\n\nUse with caution in patients with asthma or COPD (nebivolol has some beta-2 activity at higher doses), peripheral vascular disease, diabetes mellitus (may mask hypoglycemic symptoms), and in elderly patients prone to falls due to postural hypotension.\n\nAlways inform your doctor of all medications you are currently taking. Clinically significant interactions exist with other antihypertensives, NSAIDs, digoxin, antidiabetic agents, and CYP2D6 inhibitors (e.g., fluoxetine, paroxetine), which can raise nebivolol plasma levels.\n\n\n\n\n", "price": 305.0, "discountamount": 91.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2389, "imageuri": "https://productimages.withfloats.com/actual/69e9f8f745652456a0f3a497.png", "tileimageuri": "https://productimages.withfloats.com/tile/69e9f8f745652456a0f3a497.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-04-23T10:48:21.085Z", "updatedon": "2026-04-29T05:46:26.285Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/nebivolol-5mg-cilnidipine-10mg/2389", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "NEBIVALVE CILNL 5/10", "category": "CARDIOLOGYRANGE", "tags": [ "nebivolol 5mg cilnidipine 10mg", "What is nebivolol 5mg and cilnidipine 10 mg used for?", "nebivolol cilnidipine", "nebivolol cilnidipine tab", "nebivolol cilnidipine uses", "nebivolol 5mg cilnidipine 10mg price", "nebivolol 5mg cilnidipine 10mg price in india", "nebivolol cilnidipine", "nebivolol 5mg cilnidipine 10mg" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69bcff7e8538099a3d498cff", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "cilnidipine & chlorthalidone tablets", "description": "Hypertension, commonly known as high blood pressure, is a serious health condition that often goes unnoticed until it leads to major complications such as heart disease, stroke, or kidney damage. Managing blood pressure effectively requires a combination of the right medication and a healthy lifestyle. For patients who need stronger and more consistent control, combination therapies are widely recommended.\n\nCILINITAB CT is a scientifically designed combination of Cilnidipine and Chlorthalidone, offering a dual-action approach to control blood pressure. This formulation not only reduces blood pressure but also helps eliminate excess fluid from the body, making it highly effective for patients with resistant or uncontrolled hypertension.\n\nComposition\n\nCilnidipine (10 mg or as prescribed)\n\nChlorthalidone (12.5 mg or as prescribed)\n\nThis combination ensures both vascular relaxation and fluid balance, which are essential for maintaining optimal blood pressure levels.\n\nHow CILINITAB CT Works\n1. Cilnidipine Mechanism\n\nCilnidipine is a fourth-generation calcium channel blocker that works by:\n\nBlocking calcium entry into blood vessel walls\n\nRelaxing and widening blood vessels\n\nReducing peripheral vascular resistance\n\nControlling sympathetic nerve activity, which helps prevent sudden BP spikes\n\nUnlike traditional calcium channel blockers, Cilnidipine also reduces stress-related hypertension.\n\n2. Chlorthalidone Mechanism\n\nChlorthalidone is a thiazide-like diuretic (water pill) that:\n\nRemoves excess salt and water from the body through urine\n\nReduces blood volume\n\nDecreases the workload on the heart\n\nHelps maintain long-term blood pressure control\n\nCombined Effect\n\nTogether, Cilnidipine and Chlorthalidone:\n\nProvide stronger and more consistent BP reduction\n\nPrevent fluid retention\n\nImprove cardiovascular outcomes\n\nOffer better control in patients who do not respond to single-drug therapy\n\nUses of CILINITAB CT\n1. Management of Hypertension\n\nEffective in controlling moderate to severe high blood pressure\n\nSuitable for patients requiring combination therapy\n\n2. Resistant Hypertension\n\nIdeal for individuals whose BP is not controlled with one medication\n\n3. Edema (Fluid Retention)\n\nHelps reduce swelling caused by excess fluid buildup\n\n4. Cardiovascular Risk Reduction\n\nLowers the risk of heart attack, stroke, and other complications\n\nKey Benefits of CILINITAB CT\n1. Dual Mechanism for Better Control\n\nThe combination targets both blood vessel constriction and fluid overload, ensuring comprehensive blood pressure management.\n\n2. Long-Lasting Effect\n\nProvides 24-hour blood pressure control\n\nReduces the need for multiple medications\n\n3. Reduces Fluid Retention\n\nChlorthalidone helps eliminate excess fluid\n\nPrevents swelling in legs and ankles\n\n4. Protects Heart Health\n\nReduces strain on the heart\n\nImproves circulation and oxygen delivery\n\n5. Improved Tolerability\n\nCilnidipine causes less peripheral edema compared to older calcium channel blockers\n\n6. Suitable for High-Risk Patients\n\nEffective for elderly patients and those with chronic hypertension\n\n7. Enhances Treatment Compliance\n\nSingle-tablet therapy simplifies medication routine\n\nDosage and Administration\n\nTake CILINITAB CT as prescribed by your healthcare provider\n\nUsually taken once daily, preferably in the morning\n\nCan be taken with or without food\n\nDo not skip doses or stop medication abruptly\n\nSide Effects of CILINITAB CT\n\nWhile CILINITAB CT is generally well tolerated, some patients may experience side effects.\n\nCommon Side Effects\n\nDizziness\n\nHeadache\n\nFatigue\n\nIncreased urination (due to diuretic effect)\n\nMild swelling or flushing\n\nLess Common Side Effects\n\nLow blood pressure (hypotension)\n\nElectrolyte imbalance (low potassium or sodium levels)\n\nMuscle cramps\n\nNausea\n\nSerious Side Effects (Rare)\n\nSevere dehydration\n\nIrregular heartbeat\n\nKidney function abnormalities\n\nAllergic reactions (rash, itching, swelling)\n\nImmediate medical attention is required if severe symptoms occur.\n\nPrecautions and Warnings\n\nPregnancy: Not recommended due to potential risk to the fetus\n\nBreastfeeding: Consult a doctor before use\n\nKidney or Liver Disease: Use cautiously under medical supervision\n\nElectrolyte Monitoring: Regular blood tests may be required\n\nAlcohol: Avoid excessive intake as it may increase dizziness\n\nDrug Interactions: Inform your doctor about other medications, especially diuretics or antihypertensives\n\nWho Should Use CILINITAB CT?\n\nCILINITAB CT is suitable for:\n\nPatients with uncontrolled or resistant hypertension\n\nIndividuals experiencing fluid retention along with high BP\n\nPatients requiring combination therapy for better outcomes\n\nElderly patients needing stable BP control\n\nLifestyle Recommendations\n\nFor maximum effectiveness, combine medication with healthy habits:\n\nFollow a low-sodium diet\n\nEngage in regular physical activity\n\nMaintain a healthy weight\n\nAvoid smoking\n\nManage stress through relaxation techniques\n\nMonitor blood pressure regularly\n\nConclusion\n\nCILINITAB CT (Cilnidipine & Chlorthalidone Tablets) is a powerful and reliable combination therapy designed for the effective management of hypertension. By combining the vasodilatory action of cilnidipine with the diuretic effect of chlorthalidone, it ensures comprehensive control over blood pressure and fluid balance.", "price": 114.0, "discountamount": 34.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2344, "imageuri": "https://productimages.withfloats.com/actual/69bcff80a22b4293d8293ef4.png", "tileimageuri": "https://productimages.withfloats.com/tile/69bcff80a22b4293d8293ef4.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-03-20T08:04:14.07Z", "updatedon": "2026-03-20T08:04:14.07Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//cilnidipine-chlorthalidone-tablets/2344", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CILINITAB CT", "category": "CARDIOLOGYRANGE", "tags": [ "cilnidipine and chlorthalidone tablets uses", "cilnidipine chlorthalidone combination benefits", "cilnidipine chlorthalidone tablets dosage guide", "cilnidipine chlorthalidone tablets for hypertension", "cilnidipine chlorthalidone tablets dosage guide", "cilnidipine chlorthalidone tablets side effects long term", "cilnidipine chlorthalidone tablets for high bp treatment", "combination of cilnidipine and chlorthalidone benefits", "best medicine for high blood pressure cilnidipine chlorthalidone", "how to control hypertension with chlorthalidone combination", "treatment for stage 2 hypertension tablets india", "chlorthalidone combination tablets for bp control", "what is cilnidipine and chlorthalidone tablets used for", "can cilnidipine and chlorthalidone be taken together", "cilnidipine chlorthalidone tablets side effects in hindi", "buy cilnidipine chlorthalidone tablets online", "cilnidipine chlorthalidone tablets price in india", "cilnidipine chlorthalidone tablets manufacturer india", "cilnidipine chlorthalidone tablets distributor india", "affordable cilnidipine chlorthalidone tablets", "cilnidipine chlorthalidone tablets benefits in hindi", "cilnidipine chlorthalidone tablets uses in india", "cilnidipine chlorthalidone vs amlodipine comparison", "cilnidipine chlorthalidone tablets for kidney patients" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6960c83f3056ad8a5a1aecba", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Cinnarizine and Domperidone Tablets ", "description": "CLANARIZINE DOM represents an advanced pharmaceutical combination that brings together two potent therapeutic agents—Cinnarizine and Domperidone—in a single convenient tablet formulation. This innovative combination medication addresses multiple aspects of vestibular disorders, motion sickness, and associated nausea and vomiting, providing comprehensive relief for patients suffering from these debilitating conditions. Manufactured under stringent quality control standards, CLANARIZINE DOM offers a synergistic approach to managing symptoms that significantly impact quality of life and daily functioning.The combination of Cinnarizine and Domperidone in CLANARIZINE DOM is based on sound pharmacological principles. While Cinnarizine works primarily on the vestibular system to reduce dizziness and vertigo, Domperidone acts as an effective antiemetic to control nausea and vomiting. Together, these two active ingredients provide more comprehensive symptom control than either agent alone, making CLANARIZINE DOM an excellent choice for patients experiencing vestibular disturbances accompanied by gastrointestinal symptoms.This combination therapy is particularly valuable because vertigo, dizziness, and motion sickness are frequently accompanied by nausea and vomiting. Patients suffering from these conditions often find that addressing only one aspect of their symptoms provides insufficient relief. CLANARIZINE DOM's dual-action formula tackles both the underlying vestibular dysfunction and the accompanying gastrointestinal distress, offering patients a more complete therapeutic solution that improves both comfort and functional capacity.Understanding the Active IngredientsCinnarizine is a calcium channel blocker with specific antihistaminic and vestibular suppressant properties. Unlike systemic calcium channel blockers used for cardiovascular conditions, Cinnarizine selectively acts on the blood vessels in the inner ear and brain, improving blood flow to these areas. This enhanced circulation helps reduce the frequency and severity of vertigo attacks while also preventing motion sickness. Cinnarizine also possesses mild antihistaminic effects that contribute to its anti-nausea properties, though this is not its primary mechanism of action.The medication works by blocking calcium channels in the vestibular system, which helps stabilize the sensory organs responsible for balance. By reducing the excessive stimulation of the vestibular apparatus, Cinnarizine decreases the sensation of spinning or imbalance that characterizes vertigo. Additionally, its vasodilatory effects improve microcirculation in the inner ear, which can be beneficial for conditions where reduced blood flow contributes to symptoms.Domperidone is a peripheral dopamine antagonist that acts primarily as a prokinetic and antiemetic agent. Unlike some antiemetic medications that cross the blood-brain barrier and cause sedation or extrapyramidal side effects, Domperidone works predominantly in the peripheral nervous system. It blocks dopamine receptors in the chemoreceptor trigger zone (CTZ) located outside the blood-brain barrier, effectively preventing nausea and vomiting without causing significant central nervous system effects.Domperidone also enhances gastrointestinal motility by promoting coordinated contractions of the stomach and upper small intestine. This prokinetic effect helps empty the stomach more efficiently, reducing feelings of fullness, bloating, and discomfort that often accompany vestibular disorders. By accelerating gastric emptying, Domperidone also reduces the likelihood of gastroesophageal reflux, which can exacerbate nausea in some patients.The combination of these two medications in CLANARIZINE DOM creates a complementary therapeutic effect. While Cinnarizine addresses the vestibular component of dizziness and vertigo, Domperidone manages the gastrointestinal symptoms that frequently accompany these conditions. This dual approach provides more comprehensive symptom relief and improves overall treatment outcomes compared to monotherapy with either agent alone.Clinical Applications and UsesCLANARIZINE DOM is indicated for a wide range of conditions characterized by vertigo, dizziness, and associated nausea. Understanding these clinical applications helps healthcare providers select appropriate candidates for this combination therapy.Vestibular Disorders: The primary indication for CLANARIZINE DOM includes various vestibular disorders that cause vertigo and imbalance. These conditions include Ménière's disease, benign paroxysmal positional vertigo (BPPV), vestibular neuritis, and labyrinthitis. Patients with these disorders experience episodes of spinning sensation, loss of balance, and often severe nausea. CLANARIZINE DOM helps reduce the frequency and intensity of vertigo attacks while controlling the accompanying gastrointestinal symptoms.Motion Sickness: CLANARIZINE DOM is highly effective for preventing and treating motion sickness, whether related to travel by car, boat, airplane, or amusement park rides. The medication can be taken prophylactically before travel or at the onset of symptoms. The combination is particularly useful for individuals who experience severe nausea and vomiting with motion sickness, as Domperidone provides powerful antiemetic effects that complement Cinnarizine's anti-motion-sickness properties.Migraine-Associated Vertigo: Many patients with migraines experience vestibular symptoms, including dizziness, vertigo, and motion sensitivity, either during migraine attacks or as independent episodes. CLANARIZINE DOM can help manage these vestibular manifestations of migraine, reducing both the vertigo and the nausea that often accompany migraine headaches.Post-Concussion Syndrome: Following head injuries, some patients develop persistent dizziness, balance problems, and nausea as part of post-concussion syndrome. CLANARIZINE DOM may provide symptomatic relief for these patients during their recovery period, though it should be used as part of a comprehensive treatment approach that includes rest, gradual return to activities, and vestibular rehabilitation when appropriate.Cerebrovascular Insufficiency: In older adults with reduced blood flow to the brain, symptoms such as dizziness, vertigo, tinnitus (ringing in the ears), and cognitive difficulties may develop. Cinnarizine's vasodilatory properties can improve cerebral circulation, potentially reducing these symptoms. The addition of Domperidone helps manage any associated nausea.Radiation-Induced or Chemotherapy-Induced Nausea: While not a primary indication, some healthcare providers use CLANARIZINE DOM as adjunctive therapy for patients undergoing cancer treatment who experience both nausea and dizziness. Domperidone's strong antiemetic properties are particularly valuable in this context.Key Benefits of CLANARIZINE DOMThe unique combination of Cinnarizine and Domperidone in CLANARIZINE DOM offers numerous advantages that make it a preferred choice for managing vestibular disorders and associated symptoms.Comprehensive Symptom Control: The primary benefit of CLANARIZINE DOM is its ability to address multiple symptoms simultaneously. Rather than requiring patients to take separate medications for vertigo and nausea, this combination provides unified treatment in a single tablet. This comprehensive approach improves symptom control across the full spectrum of vestibular disorder manifestations, from the spinning sensation to the gastrointestinal distress that often accompanies it.Improved Patient Compliance: Taking multiple medications can be burdensome, particularly for patients who feel dizzy or nauseated. CLANARIZINE DOM simplifies the treatment regimen by combining two medications in one tablet, making it easier for patients to adhere to their prescribed therapy. Better compliance translates to better outcomes, as consistent medication use is essential for managing chronic vestibular conditions.Synergistic Therapeutic Effects: The combination of Cinnarizine and Domperidone creates synergistic effects that enhance overall efficacy. While Cinnarizine reduces vestibular stimulation and improves inner ear blood flow, Domperidone prevents nausea and promotes gastric emptying. This dual action addresses both the cause and consequences of vestibular dysfunction, providing more complete relief than either medication alone.Reduced Central Nervous System Side Effects: Because Domperidone works primarily in the peripheral nervous system rather than crossing the blood-brain barrier extensively, CLANARIZINE DOM causes less sedation and fewer cognitive effects compared to some alternative antiemetic medications. This allows patients to maintain better alertness and function during treatment, which is particularly important for those who need to continue working or performing daily activities.Enhanced Quality of Life: Vertigo and chronic dizziness significantly impair quality of life, limiting mobility, social interactions, and occupational functioning. The nausea and vomiting that accompany these conditions add another layer of disability. By effectively controlling both vestibular and gastrointestinal symptoms, CLANARIZINE DOM helps restore patients' ability to engage in normal activities, improving overall life satisfaction and functional independence.Fast Onset of Action: CLANARIZINE DOM provides relatively rapid symptom relief, with many patients experiencing improvement within 30 minutes to 2 hours after taking the medication. This quick onset is particularly valuable for acute episodes of vertigo or when taking the medication prophylactically before situations that might trigger motion sickness.Suitable for Long-Term Use: For patients with chronic vestibular disorders requiring ongoing treatment, CLANARIZINE DOM is generally safe for extended use when properly monitored by a healthcare provider. The medication maintains its effectiveness over time without significant tolerance development, making it suitable for long-term symptom management.Improved Gastric Emptying: The prokinetic effects of Domperidone benefit not only nausea but also other gastrointestinal symptoms such as early satiety, bloating, and upper abdominal discomfort. Patients with vestibular disorders often develop gastroparesis or delayed gastric emptying secondary to their condition, and Domperidone addresses this issue effectively.Vascular Benefits: Cinnarizine's ability to improve blood flow to the inner ear and brain provides additional benefits beyond symptom control. Enhanced microcirculation may support healing and recovery in conditions where vascular insufficiency contributes to vestibular dysfunction.Side Effects and Safety ConsiderationsLike all medications, CLANARIZINE DOM can cause side effects, though not everyone experiences them. Understanding potential adverse effects helps patients recognize when to seek medical attention and allows healthcare providers to monitor therapy appropriately.Common Side Effects:The most frequently reported side effect of CLANARIZINE DOM is drowsiness or sedation, occurring in approximately 10-20% of patients. This effect is primarily attributable to Cinnarizine's antihistaminic properties. Patients should avoid driving or operating machinery until they know how the medication affects them. Taking the medication at bedtime can minimize daytime drowsiness for some patients.Dry mouth is another common side effect, affecting roughly 10-15% of patients. This occurs due to anticholinergic effects and can be managed by sipping water frequently, chewing sugar-free gum, or using saliva substitutes if severe. Maintaining good oral hygiene is important to prevent dental problems associated with reduced saliva production.Mild gastrointestinal symptoms, including constipation, abdominal discomfort, or changes in bowel habits, may occur. While Domperidone promotes gastric emptying, it can occasionally alter bowel motility. These effects are usually mild and resolve with continued use or dose adjustment.", "price": 55.0, "discountamount": 17.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2271, "imageuri": "https://productimages.withfloats.com/actual/6960c8410b0da405bc908e58.png", "tileimageuri": "https://productimages.withfloats.com/tile/6960c8410b0da405bc908e58.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-09T09:19:59.281Z", "updatedon": "2026-03-12T09:24:10.244Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//cinnarizine-and-domperidone-tablets-/2271", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CLANARIZINE DOM", "category": "NEUROLOGY RANGE", "tags": [ "cinnarizine and domperidone tablet uses", "what is cinnarizine & domperidone tablet used for", "cinnarizine domperidone combination medicine benefits", "how cinnarizine domperidone tablet works", "cinnarizine domperidone tablet for vertigo treatment", "cinnarizine domperidone tablet for inner ear problem", "cinnarizine domperidone tablet for balance disorder", "cinnarizine domperidone tablet for travel sickness", "cinnarizine domperidone tablet for gastric nausea", "cinnarizine & domperidone tablet price in india", "cinnarizine domperidone tablet brand name", "cinnarizine domperidone tablet manufacturer in india" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69400227de5d3e57a9340a50", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "nebivolol and s-amlodipine tablets", "description": "NEBIVALVE AM is a combination tablet containing Nebivolol and S-Amlodipine, designed to provide effective management of hypertension (high blood pressure). Hypertension is a leading risk factor for cardiovascular diseases in India, including heart attacks, strokes, and kidney complications.\n\nThis dual-action formulation combines the benefits of Nebivolol, a cardio-selective beta-blocker, with S-Amlodipine, a calcium channel blocker, providing comprehensive blood pressure control. The combination helps relax blood vessels, improve blood flow, and reduce cardiac workload, offering a convenient and effective option for patients requiring combination therapy.\n\nUses\n\nNEBIVALVE AM is primarily prescribed for:\n\nEssential Hypertension\nLowers elevated blood pressure to reduce the risk of cardiovascular complications.\n\nCardiovascular Risk Reduction\nHelps in preventing heart attacks, strokes, and heart failure in high-risk patients.\n\nManagement of Stable Angina\nBy reducing cardiac workload and improving oxygen supply to the heart.\n\nCombination Therapy in Resistant Hypertension\nSuitable for patients who do not achieve target blood pressure with single-drug therapy.\n\nBenefits\n1. Dual Mechanism of Action\n\nNebivolol: Blocks beta-1 adrenergic receptors in the heart, reducing heart rate and cardiac output. It also promotes nitric oxide release, helping dilate blood vessels.\n\nS-Amlodipine: Relaxes vascular smooth muscles by blocking calcium channels, improving blood flow and reducing blood pressure.\n\n2. Effective Blood Pressure Control\n\nThe combination provides better blood pressure reduction compared to either drug alone, helping patients achieve their target levels faster.\n\n3. Cardiovascular Protection\n\nReduces strain on the heart, lowers risk of stroke, and supports overall heart health.\n\n4. Once-Daily Convenience\n\nThe tablet can be taken once daily, enhancing patient adherence to therapy.\n\n5. Well-Tolerated Formulation\n\nBoth Nebivolol and S-Amlodipine are generally well tolerated, minimizing side effects when used as prescribed.\n\nDosage\n\nTypical Dose: One tablet of NEBIVALVE AM once daily, preferably at the same time each day.\n\nAdministration: Swallow the tablet whole with water. Do not crush or chew.\n\nIndividualization: The dose may be adjusted by the physician based on blood pressure response and patient tolerability.\n\nLifestyle Measures: Continue dietary modifications, regular exercise, and salt restriction alongside medication for optimal results.\n\nImportant: Do not stop the medication abruptly without consulting your doctor, as sudden withdrawal may worsen blood pressure control or cardiac function.\n\nSide Effects\n\nNEBIVALVE AM is generally well tolerated, but some patients may experience mild side effects, including:\n\nDizziness or lightheadedness\n\nFatigue or weakness\n\nHeadache\n\nFlushing or swelling of ankles (edema)\n\nMild gastrointestinal discomfort\n\nRare but Serious Side Effects\n\nSlow heart rate (bradycardia)\n\nSevere hypotension (low blood pressure)\n\nWorsening of heart failure in susceptible patients\n\nAllergic reactions such as rash or swelling\n\nSeek immediate medical attention if severe symptoms such as fainting, chest pain, or shortness of breath occur.\n\nPrecautions and Warnings\n\nPregnancy and Breastfeeding: Use only if clearly indicated and prescribed by a doctor.\n\nHeart Conditions: Inform your doctor if you have heart failure, arrhythmia, or a recent heart attack.\n\nKidney or Liver Impairment: Dose adjustment may be necessary.\n\nDiabetes: Nebivolol may mask symptoms of low blood sugar; monitor blood glucose closely.\n\nDrug Interactions: Notify your doctor about all medications, especially other blood pressure drugs, anti-arrhythmics, or diuretics.\n\nAvoid Alcohol: Alcohol may increase the risk of hypotension or dizziness.\n\nRegular Monitoring: Blood pressure and heart rate should be monitored periodically during therapy.\n\nConclusion\n\nNEBIVALVE AM (Nebivolol and S-Amlodipine Tablets) is a safe and effective combination therapy for managing hypertension and reducing cardiovascular risks. By combining Nebivolol’s beta-blocking and vasodilatory effects with S-Amlodipine’s calcium channel blocking action, it provides superior blood pressure control and cardiovascular protection.", "price": 210.0, "discountamount": 63.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2246, "imageuri": "https://productimages.withfloats.com/actual/69400229d51eeda87e74dba0.png", "tileimageuri": "https://productimages.withfloats.com/tile/69400229d51eeda87e74dba0.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-15T12:42:15.327Z", "updatedon": "2026-04-18T09:07:27.461Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//nebivolol-and-s-amlodipine-tablets/2246", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "NEBIVALVE AM", "category": "CARDIOLOGY", "tags": [ "nebivolol and s-amlodipine tablets", "nebivolol and s-amlodipine tablets uses", "nebivolol and s-amlodipine tablets uses in hindi", "nebivolol", "s-amlodipine tablets", "hypertension (high blood pressure)", "kidney complications", "blood pressure contro", "helps relax blood vessels", "improve blood flow", "Hypertension is a leading risk factor for cardiovascular diseases in India", "nebivolol and s amlodipine tablets", "nebivolol s amlodipine combination tablet", "nebivolol with s amlodipine tablets", "nebivolol + s amlodipine medicine", "nebivolol s amlodipine tablet uses", "nebivolol and s amlodipine tablets uses in hypertension", "nebivolol and s-amlodipine tablets", "nebivolol and s-amlodipine tablets uses", "nebivolol and s-amlodipine", "nebivolol and s-amlodipine tablets uses in hindi", "nebivolol And s amlodipine tablets price" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "691437f0df62fb2c61ddbc40", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Ginkgo Biloba Extract and Piracetam Tablets ", "description": "Ginkgo Biloba Extract & Piracetam Tablets is a scientifically formulated neuroprotective and cognitive-enhancing combination designed to support memory, concentration, and brain function. It combines two powerful agents — Ginkgo Biloba, a time-tested herbal extract known for its circulation-enhancing and antioxidant properties, and Piracetam, a well-researched nootropic compound that enhances neuronal communication and cognitive performance.\n\nTogether, these two active ingredients work synergistically to improve cerebral blood flow, increase oxygen and nutrient delivery to the brain, and enhance mental clarity and alertness. The formulation is widely prescribed as a neurotonic and cognitive enhancer for individuals experiencing memory decline, age-related cognitive impairment, or neurological disorders such as dementia, Alzheimer’s disease, and cerebrovascular insufficiency.\n\nComposition\n\nEach film-coated tablet typically contains:\n\nGinkgo Biloba Extract (Standardized to contain 24% Flavone Glycosides & 6% Terpene Lactones) – 40 mg or 60 mg\n\nPiracetam – 800 mg\n\nExcipients – q.s.\n\nThe tablets are designed for oral administration, offering convenient dosage and high bioavailability.\n\nMechanism of Action\n1. Ginkgo Biloba Extract\n\nGinkgo Biloba, derived from the leaves of the ancient Ginkgo tree, is rich in flavonoids and terpenoids, which possess antioxidant, vasodilatory, and neuroprotective properties. It acts through several mechanisms:\n\nImproves microcirculation: Enhances blood flow to brain tissues by reducing blood viscosity and promoting vasodilation.\n\nAntioxidant action: Neutralizes free radicals that cause oxidative stress, protecting neurons from damage.\n\nIncreases neurotransmitter activity: Supports the release and uptake of acetylcholine and serotonin, improving mood and memory.\n\nReduces platelet aggregation: Improves oxygen supply to the brain and minimizes risk of ischemic injury.\n\n2. Piracetam\n\nPiracetam is a nootropic (cognitive enhancer) that improves neuronal efficiency and communication between brain cells.\nIts mechanism includes:\n\nEnhancing neuronal plasticity: Facilitates the transmission of impulses across synapses, improving learning and memory.\n\nImproving cerebral blood flow and metabolism: Enhances glucose utilization and oxygen consumption in the brain.\n\nProtecting neurons: Increases membrane fluidity and stabilizes nerve cells against hypoxic or oxidative damage.\n\nTogether, Ginkgo Biloba and Piracetam complement each other to enhance mental performance, protect neural structures, and improve cerebral function.\n\nUses and Indications\n\nGinkgo Biloba Extract & Piracetam Tablets are indicated for the following conditions:\n\nCognitive Decline and Memory Disorders:\n\nImproves memory, focus, and concentration in elderly individuals or those with mild cognitive impairment.\n\nDementia and Alzheimer’s Disease:\n\nUsed as supportive therapy to slow progression of degenerative brain disorders and enhance daily functioning.\n\nCerebrovascular Insufficiency:\n\nBeneficial in cases of reduced blood flow to the brain, helping alleviate symptoms like dizziness, headache, and mental fatigue.\n\nPost-Stroke Rehabilitation:\n\nEnhances neurological recovery and helps restore cognitive function after ischemic brain injury.\n\nVertigo and Tinnitus (Ringing in the Ears):\n\nImproves inner ear circulation, reducing dizziness and balance-related issues.\n\nLearning Disorders and Attention Deficits:\n\nImproves attention span and memory recall in both adults and children.\n\nNeuroprotective Supplement for Elderly:\n\nMaintains brain vitality and helps prevent age-related cognitive decline.\n\nKey Benefits\n\nEnhances Memory and Concentration:\nThe synergistic effect of Ginkgo Biloba and Piracetam improves synaptic transmission and neuroplasticity, enhancing learning, focus, and recall.\n\nBoosts Cerebral Circulation:\nGinkgo Biloba improves microcirculation within brain tissues, ensuring efficient delivery of oxygen and glucose to neurons.\n\nProtects Against Neurodegeneration:\nThe powerful antioxidant activity of flavonoids and terpenes from Ginkgo Biloba helps neutralize harmful free radicals, delaying age-related brain cell damage.\n\nImproves Cognitive Function in Dementia:\nClinical studies have shown improved cognition, mood, and behavior in patients with Alzheimer’s and vascular dementia with this combination.\n\nRestores Energy and Mental Clarity:\nPiracetam enhances brain metabolism and ATP synthesis, combating mental fatigue and promoting alertness.\n\nAids Recovery After Stroke or Brain Injury:\nEnhances neural regeneration, oxygen utilization, and cerebral function in post-stroke rehabilitation.\n\nReduces Dizziness, Vertigo, and Tinnitus:\nGinkgo’s vasodilatory and anti-platelet properties improve blood flow to the inner ear and brain, alleviating these symptoms.\n\nSafe and Well-Tolerated:\nNon-sedating, non-addictive, and suitable for long-term use under medical supervision.\n\nDosage and Administration\n\nAdults: One tablet two or three times daily, or as directed by a physician.\n\nElderly Patients: Dosage may be adjusted according to tolerance and medical condition.\n\nChildren: Use only if prescribed by a doctor.\n\nTablets should be swallowed whole with water, preferably after meals to avoid gastrointestinal discomfort.\n\nPrecautions and Warnings\n\nMedical Supervision Required: Should only be used under the guidance of a healthcare professional, especially for elderly patients or those on multiple medications.\n\nBleeding Disorders: Ginkgo Biloba may increase bleeding risk; avoid in patients with clotting disorders or those taking anticoagulants.\n\nSurgery: Discontinue use at least two weeks before scheduled surgery to minimize bleeding risk.\n\nEpilepsy: Piracetam may lower the seizure threshold; caution advised in epileptic patients.\n\nPregnancy and Lactation: Safety not well established; use only if prescribed by a doctor.\n\nDriving or Operating Machinery: Some individuals may experience dizziness or drowsiness; caution advised.\n\nPossible Side Effects\n\nWhile generally safe, Ginkgo Biloba Extract & Piracetam Tablets may cause mild, transient side effects in some users. These typically resolve upon dosage adjustment or discontinuation.\n\nCommon Side Effects:\n\nHeadache or mild dizziness\n\nNausea or stomach discomfort\n\nNervousness or restlessness\n\nInsomnia (if taken late in the day)\n\nLess Common Side Effects:\n\nAllergic skin rash or itching\n\nGastrointestinal upset\n\nPalpitations or rapid heartbeat\n\nMild bleeding (nosebleed, bruising) in sensitive individuals\n\nTremors (rare, usually at higher doses)\n\nSeek medical help immediately if severe allergic reactions, confusion, or unusual bleeding occur.\n\nDrug Interactions\n\nAnticoagulants and Antiplatelet Agents (e.g., Warfarin, Aspirin): May increase bleeding risk.\n\nNSAIDs (e.g., Ibuprofen): Combined use may enhance bleeding tendency.\n\nAntiepileptic Medications: Use with caution as Piracetam may affect seizure control.\n\nHerbal Supplements (e.g., Garlic, Ginseng): May potentiate anticoagulant effects.\n\nStorage and Handling\n\nStore below 30°C, protected from moisture and direct sunlight.\n\nKeep out of reach of children.\n\nDo not use tablets past the expiry date or if the blister pack is damaged.\n\nConclusion\n\nGinkgo Biloba Extract & Piracetam Tablets represent a powerful blend of herbal wisdom and modern neuroscience, formulated to promote optimal brain function and long-term cognitive health. By enhancing blood circulation to the brain, protecting neurons from oxidative damage, and improving neurotransmitter activity, this combination supports memory, focus, and mental agility across all age groups.\n\nIdeal for individuals suffering from age-related memory loss, stress-induced mental fatigue, or neurological disorders, this formulation provides comprehensive neuroprotection and cognitive enhancement in a safe, well-tolerated form.", "price": 250.0, "discountamount": 75.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2203, "imageuri": "https://productimages.withfloats.com/actual/691437f3b2490379b1b47e37.png", "tileimageuri": "https://productimages.withfloats.com/tile/691437f3b2490379b1b47e37.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-12T07:32:00.682Z", "updatedon": "2026-03-13T06:57:24.484Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//ginkgo-biloba-extract-and-piracetam-tablets-/2203", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "PATRICETAM GINKOBA", "category": "NEUROLOGY RANGE", "tags": [ "ginkgo biloba extract and piracetam tablet uses", "ginkgo biloba with piracetam benefits", "ginkgo biloba and piracetam for memory support", "ginkgo biloba piracetam dosage guide", "ginkgo biloba piracetam side effects", "ginkgo biloba piracetam combination therapy", "buy ginkgo biloba piracetam tablets online", "ginkgo biloba piracetam tablet price", "ginkgo biloba piracetam bulk order", "ginkgo biloba piracetam export supplier", "ginkgo biloba extract 60mg with piracetam tablets", "ginkgo biloba piracetam nootropic combination tablets" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69142bf71d499513a92e5772", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Nicorandil Tablets 5mg", "description": "Nicorandil Tablets 5 mg is a vasodilatory anti-anginal medication widely prescribed for the management and prevention of angina pectoris (chest pain) associated with coronary artery disease (CAD). Angina results from an imbalance between the heart’s oxygen demand and supply due to restricted blood flow in the coronary arteries. Nicorandil offers a dual mechanism of action — acting both as a nitrate-like vasodilator and a potassium channel opener, making it unique among anti-anginal agents.\n\nBy improving oxygen delivery to the myocardium and reducing cardiac workload, Nicorandil 5 mg Tablets provide effective relief from anginal pain and reduce the frequency and severity of ischemic episodes. It is also beneficial in preventing future attacks, improving exercise tolerance, and enhancing the overall quality of life in patients with chronic stable angina.\n\nComposition\n\nEach tablet contains:\n\nNicorandil IP – 5 mg\n\nExcipients – q.s.\n\nNicorandil tablets are available in film-coated form to ensure stability, easy swallowing, and optimal absorption. They are manufactured in compliance with Good Manufacturing Practices (GMP) standards to ensure safety, purity, and efficacy.\n\nPharmacological Action / Mechanism of Action\n\nNicorandil exhibits a dual mechanism that makes it distinct among anti-anginal drugs:\n\nNitrate-Like Effect:\nNicorandil acts as a nitric oxide (NO) donor. Nitric oxide activates guanylate cyclase, increasing cyclic GMP (cGMP) levels in vascular smooth muscle. This leads to relaxation of blood vessels, particularly veins and large arteries, thereby reducing preload and afterload on the heart. This nitrate-like activity lowers myocardial oxygen demand.\n\nPotassium Channel Opening Effect:\nNicorandil opens ATP-sensitive potassium (KATP) channels in vascular smooth muscle, resulting in arteriolar vasodilation. This increases coronary blood flow and improves oxygen supply to ischemic heart tissues.\n\nTogether, these effects reduce cardiac workload, enhance coronary perfusion, and prevent anginal pain by correcting the oxygen supply-demand mismatch in the heart muscle.\n\nUses and Indications\n\nNicorandil Tablets 5 mg are indicated for the treatment and prevention of angina pectoris in adults, particularly:\n\nChronic Stable Angina:\n\nHelps reduce the frequency and severity of chest pain associated with exertion or emotional stress.\n\nProphylaxis of Angina Attacks:\n\nUsed regularly to prevent anginal episodes, especially in patients with known coronary artery disease.\n\nAdjunct Therapy in Ischemic Heart Disease (IHD):\n\nCan be used alongside beta-blockers, calcium channel blockers, or antiplatelet drugs for enhanced symptom control and long-term protection.\n\nImprovement of Exercise Tolerance:\n\nReduces the likelihood of anginal pain during physical activity, enabling patients to perform daily tasks comfortably.\n\nIn some clinical cases, Nicorandil is also considered for post-myocardial infarction recovery, as it improves coronary perfusion, although this is at the discretion of a cardiologist.\n\nDosage and Administration\n\nRecommended Starting Dose: 5 mg to 10 mg twice daily.\n\nMaintenance Dose: May be increased gradually to 10–20 mg twice daily, depending on clinical response and tolerance.\n\nThe tablets should be swallowed whole with water, preferably at the same times each day.\n\nNicorandil should not be stopped abruptly; dosage tapering is recommended to avoid rebound angina.\n\nAlways follow the dosage instructions provided by the physician.\n\nKey Benefits\n\nDual Mechanism for Comprehensive Relief:\nCombines nitrate-like and potassium channel-opening properties for both arterial and venous dilation, providing superior protection against anginal attacks.\n\nImproves Coronary Blood Flow:\nDilates coronary arteries, increasing oxygen delivery to ischemic myocardial tissues.\n\nReduces Cardiac Workload:\nBy decreasing preload (venous return) and afterload (arterial resistance), Nicorandil minimizes the heart’s oxygen consumption.\n\nRapid Onset of Action:\nNicorandil acts within a short duration, offering quick relief from anginal discomfort.\n\nPrevents Future Angina Episodes:\nRegular use helps maintain steady control of chest pain, improving exercise capacity and quality of life.\n\nCompatible with Other Cardiac Medications:\nCan be safely used alongside antiplatelet agents, beta-blockers, ACE inhibitors, and statins as part of comprehensive cardiac care.\n\nFavorable Safety Profile:\nCompared to nitrates, Nicorandil carries a lower risk of tolerance development, making it suitable for long-term therapy.\n\nEnhances Myocardial Protection:\nNicorandil’s KATP channel activation provides additional cardioprotective effects by improving microvascular blood flow and limiting ischemic damage during stress.\n\nPrecautions and Warnings\n\nAlthough Nicorandil is generally well-tolerated, certain precautions are advised:\n\nHypotension:\nNicorandil may cause a drop in blood pressure due to vasodilation. Caution is advised in patients with hypotension or dehydration.\n\nConcurrent Use with Nitrates:\nShould not be used together with other nitrate medications to avoid severe hypotension.\n\nOral or Gastrointestinal Ulcers:\nRarely, Nicorandil may cause ulcerations in the mouth, intestines, or skin. Treatment should be discontinued if ulceration occurs.\n\nPatients with Low Blood Volume:\nUse cautiously in individuals with hypovolemia or those on diuretics.\n\nDriving and Machinery:\nDizziness or light-headedness may occur; avoid driving until effects are known.\n\nPregnancy and Lactation:\nShould be used only if prescribed by a physician when the potential benefits outweigh the risks.\n\nPossible Side Effects\n\nNicorandil is generally safe but may cause some side effects, particularly at the start of therapy or with higher doses. Common and rare adverse reactions include:\n\nCommon Side Effects:\n\nHeadache (due to vasodilation)\n\nFlushing or warmth sensation\n\nDizziness or light-headedness\n\nNausea or mild stomach upset\n\nFatigue or weakness\n\nLess Common / Rare Side Effects:\n\nHypotension (low blood pressure)\n\nPalpitations or tachycardia\n\nMouth ulcers, anal ulcers, or skin ulceration (uncommon but serious — discontinue if occurs)\n\nRash or allergic reaction\n\nVisual disturbances (rare and usually reversible)\n\nIf any severe reaction or persistent discomfort occurs, medical attention should be sought promptly.\n\nDrug Interactions\n\nAvoid concomitant use with nitrates or phosphodiesterase type-5 inhibitors (e.g., Sildenafil, Tadalafil), as it may cause a dangerous fall in blood pressure.\n\nCaution with antihypertensive drugs or diuretics, which may enhance hypotensive effects.\n\nAlcohol consumption can potentiate dizziness or hypotension and should be limited.\n\nStorage and Handling\n\nStore below 30°C, protected from moisture and direct sunlight.\n\nKeep out of reach of children.\n\nDo not use tablets past the expiry date or if the packaging is damaged.\n\nConclusion\n\nNicorandil Tablets 5 mg offer a modern and effective approach to managing angina pectoris, providing reliable relief through their dual-action mechanism. By combining nitrate-like vasodilation with potassium channel opening, Nicorandil ensures both oxygen supply improvement and reduction of cardiac workload — the cornerstone of angina management.\n\nIt is well-tolerated, fast-acting, and suitable for long-term therapy, making it a preferred choice for patients with chronic stable angina. Regular use under medical supervision helps reduce the frequency of chest pain, improve physical endurance, and enhance the overall quality of life in individuals with coronary artery disease.", "price": 381.0, "discountamount": 115.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2202, "imageuri": "https://productimages.withfloats.com/actual/69142c03b53db80943abd33d.png", "tileimageuri": "https://productimages.withfloats.com/tile/69142c03b53db80943abd33d.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-12T06:40:55.795Z", "updatedon": "2026-03-16T08:18:00.245Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//nicorandil-tablets-5mg/2202", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MAYORANDIL 5 ", "category": "CARDIOLOGYRANGE", "tags": [ "nicorandil tablets 5mg", "nicorandil 5 mg tablets uses", "nicorandil tablet 5mg benefits", "nicorandil 5mg medicine", "nicorandil tablets ip 5 mg", "what is nicorandil 5mg used for", "how does nicorandil tablet work", "nicorandil 5mg mechanism of action", "nicorandil tablets for angina treatment", "nicorandil tablet uses in heart disease", "nicorandil 5mg tablet price in india", "buy nicorandil 5mg tablets online", "nicorandil 5mg tablet brands", "nicorandil tablets manufacturer", "nicorandil tablets wholesale supplier" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "681b331b233d4ecb404fe2d7", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Isosorbide Mononitrate 10 mg", "description": "CARDULES ISMN 10 is a prescription medication formulated to effectively manage and prevent angina pectoris (chest pain) associated with coronary artery disease. This medicine contains Isosorbide Mononitrate (10 mg), a long-acting nitrate that helps reduce the frequency and severity of anginal episodes. It is commonly prescribed as part of a long-term treatment plan for individuals with stable angina and other cardiovascular conditions to improve heart efficiency and blood flow.\n\nKey Ingredients\nIsosorbide Mononitrate 10 mg\nIsosorbide Mononitrate is the active nitrate component in this medicine, known for its vasodilatory effects that relax blood vessels and ease the heart’s workload. It is a metabolite of isosorbide dinitrate and offers longer-lasting therapeutic benefits with fewer doses.\n\nKey Benefits\nPrevents Chest Pain (Angina): CARDULES ISMN 10 is effective in reducing the number and severity of angina attacks by improving blood flow to the heart muscle.\n\nImproves Blood Circulation: The vasodilatory action of Isosorbide Mononitrate widens the arteries and veins, facilitating better circulation and oxygen delivery.\n\nReduces Heart Workload: By dilating blood vessels, the medication decreases the heart's oxygen demand, allowing it to function more efficiently.\n\nEnhances Exercise Tolerance: Patients using this medication often experience an increase in exercise capacity, as the risk of angina during physical activity is significantly reduced.\n\nLong-Acting Relief: As a sustained nitrate, CARDULES ISMN 10 provides long-lasting protection against anginal attacks when taken regularly.\n\nHow Does It Work?\nIsosorbide Mononitrate works by releasing nitric oxide in the smooth muscle cells of blood vessels. This nitric oxide activates an enzyme called guanylate cyclase, which increases cyclic guanosine monophosphate (cGMP). The rise in cGMP levels leads to the relaxation of vascular smooth muscles, causing vasodilation. This process reduces the amount of work the heart must do and lowers myocardial oxygen consumption. As a result, blood flows more easily, and the frequency of chest pain episodes is reduced. This mechanism makes CARDULES ISMN 10 a highly effective drug in the prevention of angina.\n\nDirections for Use\nTake CARDULES ISMN 10 strictly as prescribed by your doctor.\nIt is typically taken once or twice daily, depending on the severity of the condition and the prescribing physician's guidance.\nSwallow the tablet whole with a glass of water, preferably on an empty stomach or as directed.\nDo not crush, chew, or break the tablet, as it may interfere with the drug’s effectiveness.\nFor best results, take it at the same time each day to maintain consistent blood levels.\nAvoid abrupt discontinuation of the medication unless advised by your healthcare provider.\n\nSide Effects\nWhile CARDULES ISMN 10 is generally well-tolerated, some individuals may experience side effects, especially when starting treatment or adjusting dosage. Common and less serious side effects include:\n\nHeadache\n\nDizziness or light-headedness\n\nFlushing (warmth, redness, or tingly feeling under the skin)\n\nNausea\n\nFatigue\n\nIn rare cases, more serious side effects may occur, such as:\n\nSevere hypotension (low blood pressure)\n\nFainting\n\nIrregular heartbeat\n\nAllergic reactions like rash, itching, or swelling\n\nIf any severe or unusual side effects occur, seek immediate medical attention. Regular monitoring and dose adjustments may help manage and minimize side effects.", "price": 25.0, "discountamount": 8.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": [ "commonly prescribed", "effectively manage", "angina directions", "medication decreases", "angina attacks", "stable angina", "dose adjustments", "rash itching", "rare cases", "tingly feeling", "headache dizziness", "generally welltolerated", "cardules ismn 10", "drugs effectiveness", "crush chew", "empty stomach", "water preferably", "daily depending", "process reduces", "anginal attacks", "longlasting protection", "physical activity", "exercise capacity", "veins facilitating", "vasodilatory action", "hearts workload", "cardiovascular conditions", "helps reduce", "vasodilatory effects", "starting treatment", "isosorbide dinitrate", "anginal episodes", "longacting nitrate", "side effects", "blood vessels", "experience side effects", "prescription medication formulated", "minimize side effects", "highly effective drug", "improve heart efficiency", "dilating blood vessels", "relax blood vessels", "chest pain episodes", "isosorbide mononitrate widens", "active nitrate component", "longterm treatment plan", "result blood flows", "improving blood flow", "skin nausea fatigue", "adjusting dosage common", "cgmp levels leads", "nitric oxide activates", "smooth muscle cells", "releasing nitric oxide", "coronary artery disease" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2105, "imageuri": "https://productimages.withfloats.com/actual/681b331ec4193dc2e4e9a77a.png", "tileimageuri": "https://productimages.withfloats.com/tile/681b331ec4193dc2e4e9a77a.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-05-07T10:16:59.84Z", "updatedon": "2026-03-13T08:53:37.604Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//isosorbide-mononitrate-10-mg/2105", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CARDULES ISMN 10", "category": "CARDIOLOGYRANGE", "tags": [ "Isosorbide Mononitrate 10 mg Uses in Hindi", "Isosorbide 10 mg uses", "Isosorbide mononitrate 120 mg" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6731d82c42775c6dbe6d23b5", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "minoxidil 5 finasteride 0.1 topical solution", "description": "MINOXIHAIR F ADVANCE 5% is a clinically proven topical solution designed to combat hair loss and stimulate hair regrowth. It combines two highly effective ingredients, Minoxidil (5% w/v) and Finasteride (0.1% w/v), to promote stronger, healthier hair. Whether you're dealing with male or female pattern baldness, this advanced formulation helps restore hair density and provides visible results when used consistently.\n\nKey Benefits of MINOXIHAIR F ADVANCE 5%:\n \nPromotes Hair Regrowth: The combination of Minoxidil and Finasteride stimulates the hair follicles, leading to noticeable hair regrowth over time.\nReduces Hair Loss: By inhibiting the production of DHT, Finasteride reduces the chances of hair loss, especially in individuals with pattern baldness.\nIncreases Hair Thickness: Minoxidil promotes thicker and denser hair by revitalizing dormant hair follicles.\nImproves Scalp Health: Minoxidil’s vasodilatory effects enhance blood circulation in the scalp, which nourishes hair follicles and promotes healthier hair growth.\nDual Action Formula: With the combined power of Minoxidil and Finasteride, this product addresses both the cause and symptoms of hair loss for comprehensive results.\nHow Does MINOXIHAIR F ADVANCE 5% Work?\nMINOXIHAIR F ADVANCE 5% works through a dual-action mechanism. Minoxidil stimulates hair follicles directly by increasing blood flow to the scalp and prolonging the growth phase of hair. It also helps to increase the size of hair follicles, resulting in thicker hair strands.\n\nFinasteride works internally by inhibiting the enzyme 5-alpha-reductase, which converts testosterone into DHT. By lowering DHT levels in the scalp, Finasteride prevents hair follicles from shrinking, which is the leading cause of pattern baldness. This dual action makes MINOXIHAIR F ADVANCE 5% highly effective in treating hair loss and improving hair density.\n\n \nDirections for Use:\n \n\nClean and Dry the Scalp: Wash your scalp with a mild shampoo and dry it completely before application.\nApply the Solution: Using the provided dropper, apply MINOXIHAIR F ADVANCE 5% directly to the affected areas of the scalp. Typically, 1ml of the solution should be applied twice a day (morning and night) to clean, dry hair.\nMassage Gently: Gently massage the solution into the scalp to ensure even distribution.\nAllow to Dry: Let the solution dry completely before styling your hair or wearing headgear.\nConsistency is Key: For optimal results, use the solution consistently and regularly for several months. It may take at least 4-6 months to begin seeing noticeable results.\n \nSide Effects:\n\nMINOXIHAIR F ADVANCE 5% is generally well-tolerated; however, like any medication, it may cause side effects in some individuals. Common side effects include:\nScalp Irritation: Some users may experience dryness, itching, or flaking at the application site.\nDizziness or Lightheadedness: Though rare, some individuals may feel lightheaded or dizzy when standing up quickly.\nUnwanted Facial Hair Growth: In women, Minoxidil may cause unwanted hair growth on the face or hands if the product comes into contact with these areas.\nDecrease in Libido: Finasteride can occasionally cause a decrease in sexual desire or performance.\nChest Pain or Palpitations: Some users may experience a mild sensation of chest tightness or heart palpitations, though these symptoms are uncommon.\nAllergic Reactions: Signs of an allergic reaction, such as swelling, rash, or difficulty breathing, require immediate medical attention.", "price": 796.0, "discountamount": 239.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "hair loss", "DHT levels", "Chest Pain", "4-6 months", "blood flow", "denser hair", "Scalp Health", "mild shampoo", "Key Benefits", "hair density", "growth phase", "leading cause", "sexual desire", "affected areas", "mild sensation", "several months", "combined power", "Hair Thickness", "chest tightness", "optimal results", "visible results", "clean, dry hair", "topical solution", "Scalp Irritation", "application site", "blood circulation", "heart palpitations", "Allergic Reactions", "noticeable results", "Common side effects", "Dual Action Formula", "advanced formulation", "vasodilatory effects", "thicker hair strands", "unwanted hair growth", "MINOXIHAIR F ADVANCE", "dual-action mechanism", "comprehensive results", "healthier hair growth", "dormant hair follicles", "female pattern baldness", "enzyme 5-alpha-reductase", "noticeable hair regrowth", "stronger, healthier hair", "immediate medical attention", "Unwanted Facial Hair Growth", "two highly effective ingredients" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2026, "imageuri": "https://productimages.withfloats.com/actual/693919285b46dc417306fc24.png", "tileimageuri": "https://productimages.withfloats.com/tile/693919285b46dc417306fc24.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-11-11T10:10:52.667Z", "updatedon": "2026-03-13T10:56:42.823Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//minoxidil-5-finasteride-0-1-topical-solution/2026", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MINOXIHAIR F ADVANCE 5% ", "category": "DERMATALOGY", "tags": [ "Minoxihair f advance 5% review", "Minoxidil and Finasteride topical solution buy onl", "minoxidil + finasteride topical solution reviews", "hair loss and stimulate hair regrowth", "male or female pattern baldness", "this advanced formulation helps restore hair density", "Promotes Hair Regrowth", "chest tightness or heart palpitations", "to promote stronger, healthier hair", "minoxidil finasteride solution", "minoxidil 5 finasteride 0.1 topical solution", "minoxidil 5% finasteride 0.1% solution", "minoxidil finasteride topical solution 5 percent", "minoxidil finasteride hair solution", "how minoxidil 5 finasteride 0.1 topical solution works", "benefits of minoxidil finasteride topical solution", "minoxidil finasteride topical solution uses", "minoxidil finasteride solution for hair regrowth", "finasteride 0.1 topical vs oral finasteride", "minoxidil 5 finasteride 0.1 topical solution price", "minoxidil finasteride topical solution buy online", "minoxidil finasteride topical solution in india", "minoxidil finasteride combination topical solution", "best minoxidil finasteride topical solution brand", "minoxidil finasteride topical solution review", "minoxidil 5 vs minoxidil finasteride topical solution", "finasteride topical 0.1 with minoxidil effectiveness", "minoxidil finasteride solution results timeline", "minoxidil 5 finasteride 0.1 topical solution for men", "finasteride 0.1 topical minoxidil daily use", "minoxidil finasteride topical solution for early hair loss", "minoxidil finasteride solution side effects topical" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6abe4471401ae1a1106d67d9", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Bisoprolol 1.25mg", "description": "Bisoprolol 1.25mg is the smallest tablet strength of bisoprolol, a heart-selective beta-1 blocker. Doctors usually prescribe it to start treatment or to build up the dose gradually in people with high blood pressure, chronic stable heart failure, or fast heart rhythms. It suits older adults, people with mild heart failure, and anyone who reacts strongly to beta-blockers. The medicine slows the heartbeat and eases the force of each contraction, so the heart works less hard. BISOGARD 1.25 from Steris Healthcare Pvt. Ltd. comes in a strip pack of 15 tablets. It is a Schedule H medicine, so it must only be started, changed, or stopped on a doctor's advice.\n\nProduct Snapshot\n\nBrand: BISOGARD 1.25\nManufacturer/Marketer: Steris Healthcare Pvt. Ltd., a WHO-GMP and ISO-certified pharmaceutical company in India\nActive ingredient: Bisoprolol Fumarate 1.25mg\nForm: Tablet\nPack size: 15 tablets\nDrug class: Cardioselective beta-1 blocker\nLegal status: Schedule H (valid prescription required)\nAvailability: Through Steris Healthcare's authorized pharmacies and its B2B PCD franchise network across India\nWhat Is Bisoprolol 1.25mg?\n\nIf your doctor has just prescribed bisoprolol 1.25mg, you have been given the lowest dose on purpose. Bisoprolol is a cardioselective beta-1 blocker, meaning it acts mostly on receptors in the heart and has much less effect on the lungs and blood vessels. This is a major reason it is preferred over older, non-selective beta-blockers, especially for people who also have a mild breathing problem.\n\nThe 1.25mg tablet is not a “light” medicine for mild illness. It is a carefully chosen entry point. In heart failure, a weakened heart can struggle if its rate or pressure drops too quickly, so cardiologists follow a “start low, go slow” approach. Treatment begins at 1.25mg, the response is watched for one to two weeks, and the dose is raised step by step (commonly 2.5mg, 3.75mg, 5mg, 7.5mg, and up to 10mg) as the heart adapts. That is why BISOGARD 1.25 is often the first tablet a newly diagnosed heart failure patient takes.\n\nWhat Is Bisoprolol 1.25mg Used For?\n\nDoctors commonly prescribe this strength for:\n\nChronic heart failure (HFrEF): as the first step of dose titration in patients with a reduced ejection fraction, alongside ACE inhibitors/ARBs and diuretics\nHigh blood pressure: especially in older adults, people with low body weight, and those who are sensitive to blood-pressure-lowering drugs\nStable angina: to reduce the heart's oxygen demand and relieve chest discomfort\nAfter a heart attack: in selected patients, under a cardiologist's care\nHeart rate control in some arrhythmias: sometimes used off-label at a low dose to gently bring down a fast heart rate\n\nAt 1.25mg, bisoprolol is seldom meant as the long-term sole treatment for high blood pressure in an otherwise healthy adult. It is usually the first rung of a titration ladder, or a steady maintenance dose for patients who are unusually beta-blocker sensitive (older age, low body weight, or borderline low pressure or pulse).\n\nHow Does Bisoprolol Work?\n\nBisoprolol selectively blocks beta-1 adrenergic receptors, which are packed mainly into heart muscle. This leads to several effects:\n\nSlower heart rate: the heart has more time to fill and rest between beats\nGentler contractions: the heart muscle needs less oxygen and energy\nLess renin from the kidneys: this helps blood pressure fall gradually over time\nLower overall cardiac workload: a real advantage for a heart that already struggles to pump well, as in heart failure\nKey Benefits of BISOGARD 1.25\nA gentle starting dose, well suited to careful titration in frail or elderly patients\nHeart-focused action, with less effect on the lungs and peripheral blood vessels than non-selective beta-blockers\nOnce-daily dosing, which makes it easier to stay on treatment\nA guideline-recommended beta-blocker for HFrEF with well-established outcomes data [Reviewer note: insert specific outcome statistics/trial citation pending medical sign-off]\nMade by Steris Healthcare Pvt. Ltd. under WHO-GMP and ISO-certified standards\nDosage Guidance\nUsual starting dose (heart failure): 1.25mg once a day, preferably in the morning\nDose increases: typically every 1–2 weeks (2.5mg, 3.75mg, 5mg, 7.5mg, up to a maximum of 10mg daily), depending on how well you tolerate it and on your pulse and blood pressure\nHigh blood pressure (sensitive patients): 1.25mg to 5mg once daily, as set by your doctor\nHow to take it: at the same time every day, with or without food, swallowed whole with water\nIf you miss a dose: take it when you remember, unless the next dose is almost due. Never take a double dose.\nNever stop suddenly: abrupt withdrawal can cause a rebound rise in heart rate, blood pressure, or chest pain. The dose must be reduced gradually under medical supervision.\nIs It Better to Take Bisoprolol in the Morning or at Night?\n\nMost doctors advise a morning dose. Bisoprolol lowers pulse and blood pressure, and taking it early matches its action to your daytime activity. A night-time dose could add to the body's natural overnight dip in blood pressure and raise the chance of dizziness when getting up in the dark. Some people who feel tired during the day are told by their doctor to switch to the evening. Do not change your dosing time without your doctor's approval.\n\nSide Effects of Bisoprolol 1.25mg\n\nCommon side effects\n\nTiredness or fatigue\nDizziness or light-headedness, especially on standing quickly\nCold hands or feet\nSlow pulse (bradycardia)\nHeadache\nMild stomach upset (nausea, loose stools)\nDisturbed sleep\n\nSerious side effects (get medical help promptly)\n\nVery slow heartbeat or fainting\nIncreasing breathlessness or swollen legs/ankles, which may mean heart failure is worsening\nAllergic reaction: rash, swelling of the face or throat, trouble breathing\nCold, numb, or bluish fingers and toes\nWheezing or new breathing difficulty, particularly in people with asthma or COPD\nMood changes, low mood, or confusion\nWhat Are the Bad Side Effects of Bisoprolol?\n\nThe effects that need urgent attention are a dangerously slow pulse, fainting, signs of worsening heart failure (swelling, breathlessness), severe allergic reactions, and airway tightening in people with lung disease. These are uncommon at the 1.25mg dose, but anyone who notices them should seek medical help right away. [Reviewer note: specific incidence rates pending clinical/medical sign-off]\n\nSubstitutes & Comparable Beta-Blockers\nMolecule\tSelectivity\tTypical Use Case\nBisoprolol\tHighly cardioselective\tHeart failure titration, hypertension\nMetoprolol Succinate ER\tCardioselective\tHypertension, angina, heart failure\nAtenolol\tCardioselective (older agent)\tHypertension\nCarvedilol\tNon-selective with alpha-blocking action\tHeart failure (adds vasodilation)\nPropranolol\tNon-selective\tMigraine prevention, anxiety-related fast heartbeat, essential tremor\nPrecautions & Who Should Avoid Bisoprolol\nNot suitable for people with severe bradycardia, certain forms of heart block (unless a pacemaker is fitted), unstable or acutely decompensated heart failure, or severe uncontrolled asthma\nUse carefully in diabetes, because beta-blockers can hide the warning signs of low blood sugar\nTake care in peripheral vascular disease, as cold extremities or leg pain on walking may worsen\nNever stop it abruptly; always taper under a doctor's guidance\nTell your doctor about every medicine you use, especially other blood-pressure drugs, calcium channel blockers, and certain antiarrhythmics\nIn pregnancy and breastfeeding, use only if your doctor advises it after weighing benefits and risks\nIs Bisoprolol Safe for Kidneys?\n\nThe body clears bisoprolol through both the liver and the kidneys in roughly equal measure. It is generally considered safe for people with normal or mildly reduced kidney function. When kidney impairment is significant, drug levels in the blood can rise, so your doctor may lower the dose or monitor you more closely. Always tell your prescriber about any kidney disease before starting.\n\nIs Bisoprolol a High-Risk Medication?\n\nBisoprolol is not a narrow therapeutic index drug like tacrolimus or warfarin, where small dose differences matter greatly. Even so, it needs supervised use because it directly affects heart rate and blood pressure. The main dangers are stopping it suddenly, which can set off rebound cardiac events, and using it with certain existing rhythm disorders. Taken as prescribed and checked regularly, it has a long and reassuring safety record.\n\nDoes 1.25mg Bisoprolol Lower Blood Pressure?\n\nYes. Even the smallest dose measurably reduces heart rate and blood pressure by lightening the heart's workload and reducing renin-driven narrowing of blood vessels. At this strength the effect on blood pressure is fairly mild, which is exactly why it is a safe place to begin, especially for older adults or people starting heart failure treatment. The dose is then raised gradually to reach full benefit.\n\nFrequently Asked Questions\n\n1. What is 1.25 mg of bisoprolol used for?\nMainly as a low starting dose when building up treatment for chronic heart failure, and for high blood pressure in people who are very sensitive to beta-blockers, such as older adults.\n\n2. What are the bad side effects of bisoprolol?\nThe more serious ones are a very slow pulse, fainting, worsening heart failure signs (swelling, breathlessness), severe allergy, and breathing trouble in people with lung conditions.\n\n3. What are the common side effects of bisoprolol fumarate 1.25 mg tablets?\nTiredness, dizziness, cold hands and feet, mild headache, and a slightly slower pulse.\n\n4. Is it better to take bisoprolol in the morning or at night?\nMorning is usually preferred so its effect fits daytime activity, though your doctor may suggest evenings in some cases.\n\n5. What is the cost of bisoprolol?\nPrice depends on strength, pack size, and brand. Use the “Check Price” option above for current BISOGARD 1.25 pricing from Steris Healthcare.\n\n6. Does 1.25 mg bisoprolol lower blood pressure?\nYes, though only modestly at this dose. The dose is often stepped up over time.\n\n7. Is bisoprolol safe for kidneys?\nGenerally yes for normal or mildly reduced kidney function. People with significant kidney impairment need dose adjustment and monitoring.\n\n8. Is bisoprolol a high-risk medication?\nIt is not a narrow therapeutic index drug, but it must never be stopped suddenly and should be used under medical supervision because of its direct effect on the heart.\n\n9. Can I take bisoprolol 1.25mg for the rest of my life?\nMany people with chronic heart failure or hypertension do take bisoprolol long term, but the dose usually rises as tolerated. Your doctor should review it regularly.\n\n10. What happens if I miss a dose of bisoprolol?\nTake it when you remember, unless the next dose is nearly due. In that case skip the missed one. Never take two together.\n\n11. Can bisoprolol 1.25mg cause weight gain?\nIt is not commonly reported at this dose. Fluid retention linked to heart failure itself should be reported to your doctor.\n\n12. Is bisoprolol safe for diabetic patients?\nIt can be used, with care, because beta-blockers may hide warning signs of low blood sugar such as a racing heartbeat.\n\n13. Can I stop taking bisoprolol suddenly if I feel fine?\nNo. Stopping abruptly can cause a rebound rise in heart rate, blood pressure, or chest pain. Reduce the dose gradually under medical guidance.\n\n14. Does bisoprolol interact with other blood pressure medicines?\nYes. Combining it with other drugs that lower heart rate or pressure (such as calcium channel blockers) can cause a very low pulse or pressure. Tell your doctor about all your medicines.\n\n15. Is BISOGARD 1.25 available without a prescription?\nNo. Bisoprolol is a Schedule H medicine in India and needs a valid prescription.\n\n16. How long does it take for bisoprolol 1.25mg to start working?\nSome effect on heart rate appears within hours, but the full benefit for blood pressure or heart failure symptoms builds over several weeks of regular use.\n\n17. Can pregnant women take bisoprolol?\nOnly if clearly necessary and prescribed by a doctor, as it may affect the baby's heart rate and growth.", "price": 39.0, "discountamount": 12.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2501, "imageuri": "https://productimages.withfloats.com/actual/6abe4474c205678e0b16a23a.png", "tileimageuri": "https://productimages.withfloats.com/tile/6abe4474c205678e0b16a23a.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-10-01T11:30:57.88Z", "updatedon": "2026-10-01T11:30:57.88Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//bisoprolol-1-25mg/2501", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Bisogard 1.25", "category": "CARDIOLOGYRANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false } ], "hasmoreitems": false, "isapirequest": false, "totalresults": 27, "query": null, "floatingpoint": null }