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{ "products": [ { "_id": "68b6d6c76f14ecfa6add5d56", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "SACUSMART 200", "description": "Description: \nSACUSMART 200 is a combination medicine containing Sacubitril (97 mg) and Valsartan (103 mg), specifically designed to manage chronic heart failure with reduced ejection fraction (HFrEF). This dual-acting therapy is classified as an angiotensin receptor neprilysin inhibitor (ARNI) and is widely prescribed to reduce the risk of cardiovascular death and hospitalization in patients with heart failure.\n\nHeart failure is a progressive condition where the heart cannot pump blood efficiently to meet the body’s needs. SACUSMART 200 improves the efficiency of the heart by relaxing blood vessels, reducing fluid retention, and lowering strain on the heart, helping patients live a better and longer life.\n\n \nWhat is SACUSMART 200?\n \n\nSACUSMART 200 is a highly effective heart failure medication that combines two active components:\n\nSacubitril (97 mg) – a neprilysin inhibitor that increases levels of natriuretic peptides, leading to vasodilation, sodium excretion, and reduced stress on the heart.\n\nValsartan (103 mg) – an angiotensin II receptor blocker (ARB) that relaxes blood vessels, lowers blood pressure, and prevents harmful effects of angiotensin II.\n\nTogether, these mechanisms make SACUSMART 200 a superior alternative to traditional ACE inhibitors or ARBs alone in treating chronic heart failure.\n\n \nUses of SACUSMART 200\n \n\nSACUSMART 200 is prescribed for:\n\nChronic heart failure with reduced ejection fraction (HFrEF)\n\nReducing risk of hospitalization due to worsening heart failure\n\nImproving survival rates in patients with heart failure\n\nEnhancing exercise tolerance and quality of life in long-term heart failure management\n\n \nBenefits of SACUSMART 200\n \n\nDual action with neprilysin inhibition + ARB effect for comprehensive heart protection\n\nProven to reduce mortality and hospitalization risk in heart failure patients\n\nImproves symptoms such as breathlessness, fatigue, and swelling\n\nHelps patients regain better physical stamina and daily activity levels\n\nLong-term use significantly contributes to improved quality of life\n\n \nPossible Side Effects of SACUSMART 200\n \n\nWhile SACUSMART 200 is effective and generally well tolerated, some patients may experience:\n\nLow blood pressure (hypotension)\n\nIncreased blood potassium levels (hyperkalemia)\n\nDizziness or light-headedness\n\nKidney function changes\n\nCough\n\nRarely, serious allergic reactions or angioedema (swelling of face, lips, or throat)\n\nImmediate medical attention is required if severe swelling, difficulty breathing, or fainting occurs.\n\n \nPrecautions Before Using SACUSMART 200\n \n\nDo not use if you are allergic to sacubitril, valsartan, or other ARBs\n\nAvoid if you have taken an ACE inhibitor within the last 36 hours due to the risk of angioedema\n\nNot recommended for patients with a history of hereditary angioedema\n\nCaution in patients with severe kidney or liver disease\n\nPregnant and breastfeeding women should avoid this medicine due to harmful effects on the baby\n\nAlways monitor blood pressure, kidney function, and potassium levels while on this treatment\n\n \nDrug Interactions\n \n\nSACUSMART 200 may interact with:\n\nACE inhibitors – should not be combined, risk of angioedema\n\nPotassium supplements or potassium-sparing diuretics – risk of high potassium\n\nNSAIDs (e.g., ibuprofen, naproxen) – may reduce kidney function\n\nLithium – risk of lithium toxicity\n\nDiuretics – may increase the risk of low blood pressure\n\nAlways inform your doctor about all medicines, supplements, or herbal products you are taking before starting SACUSMART 200.\n\n \nConclusion\n \n\nSACUSMART 200 (Sacubitril 97 mg & Valsartan 103 mg) is a breakthrough treatment in managing chronic heart failure with reduced ejection fraction (HFrEF). By combining neprilysin inhibition and angiotensin receptor blockade, it not only reduces symptoms but also significantly lowers the risk of hospitalization and death, improving both longevity and quality of life.\n\nFor patients living with heart failure, SACUSMART 200 offers a scientifically proven and clinically superior solution to regain control over their health and live a more fulfilling life.", "price": 750.0, "discountamount": 225.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2170, "imageuri": "https://productimages.withfloats.com/actual/68b6d6c9c4087f14f55d7d23.png", "tileimageuri": "https://productimages.withfloats.com/tile/68b6d6c9c4087f14f55d7d23.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-09-02T11:36:39.17Z", "updatedon": "2025-09-02T11:36:39.17Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/sacusmart-200/2170", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Sacubitril and Valsartan Tablets (97 mg + 103 mg)", "category": "CARDIOLOGYRANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "681b331b233d4ecb404fe2d7", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "CARDULES ISMN 10", "description": "CARDULES ISMN 10 is a prescription medication formulated to effectively manage and prevent angina pectoris (chest pain) associated with coronary artery disease. This medicine contains Isosorbide Mononitrate (10 mg), a long-acting nitrate that helps reduce the frequency and severity of anginal episodes. It is commonly prescribed as part of a long-term treatment plan for individuals with stable angina and other cardiovascular conditions to improve heart efficiency and blood flow.\n\nKey Ingredients\nIsosorbide Mononitrate 10 mg\nIsosorbide Mononitrate is the active nitrate component in this medicine, known for its vasodilatory effects that relax blood vessels and ease the heart’s workload. It is a metabolite of isosorbide dinitrate and offers longer-lasting therapeutic benefits with fewer doses.\n\nKey Benefits\nPrevents Chest Pain (Angina): CARDULES ISMN 10 is effective in reducing the number and severity of angina attacks by improving blood flow to the heart muscle.\n\nImproves Blood Circulation: The vasodilatory action of Isosorbide Mononitrate widens the arteries and veins, facilitating better circulation and oxygen delivery.\n\nReduces Heart Workload: By dilating blood vessels, the medication decreases the heart's oxygen demand, allowing it to function more efficiently.\n\nEnhances Exercise Tolerance: Patients using this medication often experience an increase in exercise capacity, as the risk of angina during physical activity is significantly reduced.\n\nLong-Acting Relief: As a sustained nitrate, CARDULES ISMN 10 provides long-lasting protection against anginal attacks when taken regularly.\n\nHow Does It Work?\nIsosorbide Mononitrate works by releasing nitric oxide in the smooth muscle cells of blood vessels. This nitric oxide activates an enzyme called guanylate cyclase, which increases cyclic guanosine monophosphate (cGMP). The rise in cGMP levels leads to the relaxation of vascular smooth muscles, causing vasodilation. This process reduces the amount of work the heart must do and lowers myocardial oxygen consumption. As a result, blood flows more easily, and the frequency of chest pain episodes is reduced. This mechanism makes CARDULES ISMN 10 a highly effective drug in the prevention of angina.\n\nDirections for Use\nTake CARDULES ISMN 10 strictly as prescribed by your doctor.\nIt is typically taken once or twice daily, depending on the severity of the condition and the prescribing physician's guidance.\nSwallow the tablet whole with a glass of water, preferably on an empty stomach or as directed.\nDo not crush, chew, or break the tablet, as it may interfere with the drug’s effectiveness.\nFor best results, take it at the same time each day to maintain consistent blood levels.\nAvoid abrupt discontinuation of the medication unless advised by your healthcare provider.\n\nSide Effects\nWhile CARDULES ISMN 10 is generally well-tolerated, some individuals may experience side effects, especially when starting treatment or adjusting dosage. Common and less serious side effects include:\n\nHeadache\n\nDizziness or light-headedness\n\nFlushing (warmth, redness, or tingly feeling under the skin)\n\nNausea\n\nFatigue\n\nIn rare cases, more serious side effects may occur, such as:\n\nSevere hypotension (low blood pressure)\n\nFainting\n\nIrregular heartbeat\n\nAllergic reactions like rash, itching, or swelling\n\nIf any severe or unusual side effects occur, seek immediate medical attention. Regular monitoring and dose adjustments may help manage and minimize side effects.", "price": 25.0, "discountamount": 8.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": [ "commonly prescribed", "effectively manage", "angina directions", "medication decreases", "angina attacks", "stable angina", "dose adjustments", "rash itching", "rare cases", "tingly feeling", "headache dizziness", "generally welltolerated", "cardules ismn 10", "drugs effectiveness", "crush chew", "empty stomach", "water preferably", "daily depending", "process reduces", "anginal attacks", "longlasting protection", "physical activity", "exercise capacity", "veins facilitating", "vasodilatory action", "hearts workload", "cardiovascular conditions", "helps reduce", "vasodilatory effects", "starting treatment", "isosorbide dinitrate", "anginal episodes", "longacting nitrate", "side effects", "blood vessels", "experience side effects", "prescription medication formulated", "minimize side effects", "highly effective drug", "improve heart efficiency", "dilating blood vessels", "relax blood vessels", "chest pain episodes", "isosorbide mononitrate widens", "active nitrate component", "longterm treatment plan", "result blood flows", "improving blood flow", "skin nausea fatigue", "adjusting dosage common", "cgmp levels leads", "nitric oxide activates", "smooth muscle cells", "releasing nitric oxide", "coronary artery disease" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2105, "imageuri": "https://productimages.withfloats.com/actual/681b331ec4193dc2e4e9a77a.png", "tileimageuri": "https://productimages.withfloats.com/tile/681b331ec4193dc2e4e9a77a.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-05-07T10:16:59.84Z", "updatedon": "2025-05-07T10:17:52.427Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/cardules-ismn-10/2105", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "", "category": "CARDIOLOGYRANGE", "tags": [ "Isosorbide Mononitrate 10 mg Uses in Hindi", "Isosorbide 10 mg uses", "Isosorbide mononitrate 120 mg" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "681b2e1131166af9fb0be5c3", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "CARDULES ISDN 5", "description": "CARDULES ISDN 5 is a prescription medication formulated with Isosorbide Dinitrate (5 mg), a well-known nitrate used to prevent and treat chest pain (angina) caused by coronary artery disease. This medicine is commonly prescribed to improve blood flow to the heart and reduce the frequency and severity of anginal attacks. It works by relaxing the blood vessels, making it easier for the heart to pump blood, and reducing its oxygen demand. CARDULES ISDN 5 is especially useful for long-term management of chronic angina and can be an essential part of a comprehensive cardiac care plan.\n\nKey Ingredients\nIsosorbide Dinitrate (5 mg) – This is the active pharmaceutical ingredient in CARDULES ISDN 5. Belonging to the nitrate class of drugs, Isosorbide Dinitrate helps widen and relax blood vessels, thereby improving blood flow and oxygen delivery to the heart muscle.\n\nKey Benefits\nProvides effective relief from angina (chest pain)\n\nHelps prevent angina episodes when taken regularly\n\nImproves blood circulation to the heart\n\nReduces the heart's workload and oxygen demand\n\nSupports overall cardiac function in patients with coronary artery disease\n\nCan improve exercise tolerance and reduce anginal frequency\n\nHow Does It Work?\nCARDULES ISDN 5 works by releasing nitric oxide within the vascular smooth muscle, leading to the relaxation of blood vessels. This vasodilation effect reduces the amount of work the heart must do to pump blood and lowers its oxygen demand. By widening the arteries and veins, Isosorbide Dinitrate facilitates better oxygen delivery to the heart tissue, which helps prevent angina attacks. It is especially effective in preventing episodes when used on a regular schedule, rather than providing immediate relief during an ongoing attack.\n\nDirections for Use\nAlways take CARDULES ISDN 5 exactly as prescribed by your physician.\n\nTypically taken orally, with or without food.\n\nIt is important to take the medication at the same times each day to maintain consistent nitrate levels in the bloodstream.\n\nSwallow the tablet whole with water; do not crush or chew unless advised.\n\nDo not stop the medication abruptly without consulting your doctor, as it may worsen angina symptoms.\n\nSide Effects\nWhile CARDULES ISDN 5 is generally well-tolerated, some individuals may experience side effects. These can include:\n\nHeadache (commonly occurs initially and often subsides with continued use)\n\nDizziness or light-headedness, especially when rising from a sitting or lying position\n\nNausea or vomiting\n\nFlushing or warmth of the skin\n\nLow blood pressure (hypotension)\n\nRapid heartbeat (tachycardia)\n\nIn rare cases, allergic reactions or more serious cardiovascular effects may occur. Always report any persistent or severe side effects to your healthcare provider immediately.\n\n", "price": 45.0, "discountamount": 14.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": [ "effective relief", "heart tissue", "commonly prescribed", "heart reduces", "vomiting flushing", "generally welltolerated", "medication abruptly", "bloodstream swallow", "physician typically", "cardules ismn 5", "regular schedule", "preventing episodes", "cardiac function", "hearts workload", "nitrate class", "essential part", "chronic angina", "longterm management", "wellknown nitrate", "oxygen delivery", "anginal attacks", "pump blood", "cardiovascular effects", "oxygen demand", "blood vessels", "reduce anginal frequency", "oxygen demand supports", "prescription medication formulated", "relax blood vessels", "blood vessels making", "vasodilation effect reduces", "improving blood flow", "improve blood flow", "severe side effects", "experience side effects", "healthcare provider immediately", "lying position nausea", "ongoing attack directions", "releasing nitric oxide", "improve exercise tolerance", "active pharmaceutical ingredient", "coronary artery disease" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2104, "imageuri": "https://productimages.withfloats.com/actual/681b2e1454203247c379193a.png", "tileimageuri": "https://productimages.withfloats.com/tile/681b2e1454203247c379193a.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-05-07T09:55:29.776Z", "updatedon": "2025-05-07T11:03:42.288Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/cardules-isdn-5/2104", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Isosorbide Dinitrate 5mg", "category": "CARDIOLOGYRANGE", "tags": [ "Isosorbide dinitrate 5 mg uses", "Isosorbide dinitrate uses", "Isosorbide Dinitrate 5 mg price", "Isosorbide dinitrate dosage" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "666975897e4bb91e3091ff69", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "CILOSTAZONE 100 ", "description": "CILOSTAZONE 100 \nCilostazol (100mg)\nIntroduction\nCILOSTAZONE 100 contains Cilostazol (100 mg), a potent medication used to treat the symptoms of intermittent claudication in individuals with peripheral artery disease (PAD). By improving blood flow and reducing pain during physical activity, Cilostazol enables patients to walk longer distances and engage more comfortably in daily activities.\n\nKey Ingredient and Its Benefits\nCilostazol (100 mg)\nImproved Blood Flow: Cilostazol works by inhibiting phosphodiesterase III, leading to an increase in cyclic AMP levels, which causes vasodilation and improves blood flow to the limbs.\nReduced Pain: It effectively reduces pain and discomfort in the legs associated with intermittent claudication, allowing patients to walk longer distances without pain.\nPlatelet Aggregation Inhibition: Cilostazol inhibits platelet aggregation, reducing the risk of blood clots and enhancing cardiovascular health.\nEnhanced Physical Activity: By alleviating symptoms of intermittent claudication, Cilostazol helps patients increase their physical activity and improve overall fitness.\nBenefits of CILOSTAZONE 100\nEffective Symptom Relief: CILOSTAZONE 100 provides robust relief from intermittent claudication symptoms, significantly reducing pain and discomfort in the legs.\nImproved Circulation: The medication enhances blood flow to the extremities, improving circulation and overall vascular health.\nIncreased Mobility: By reducing pain during walking, CILOSTAZONE 100 enables patients to increase their mobility and engage more actively in daily activities.\nPrevention of Blood Clots: Cilostazol’s platelet aggregation inhibition properties help prevent blood clot formation, reducing the risk of cardiovascular events.\nDosage and Administration\nDosage\nIntermittent Claudication: The typical dosage for adults is one tablet (100 mg) taken twice daily, 30 minutes before or 2 hours after breakfast and dinner. The dosage may be adjusted by the healthcare provider based on the patient’s response and specific health needs.\nAdministration\nOral Use: Swallow the tablet whole with a full glass of water. It should be taken on an empty stomach, either 30 minutes before or 2 hours after meals.\nConsistency: For optimal results, take CILOSTAZONE 100 at the same times each day to maintain consistent medication levels in your bloodstream.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order NOW \nhttps://www.sterisonline.com/product/cilostazone-100-133550", "price": 191.5, "discountamount": 57.45, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "mg", "PAD", "risk", "legs", "Order", "EMAIL", "limbs", "meals", "water", "adults", "dinner", "walking", "patients", "response", "Benefits", "Oral Use", "breakfast", "Prevention", "Cilostazol", "same times", "discomfort", "one tablet", "full glass", "individuals", "CILOSTAZONE", "extremities", "blood clots", "Consistency", "bloodstream", "information", "Introduction", "sterispharma", "vasodilation", "Reduced Pain", "sterisonline", "CALL/WHATSAPP", "robust relief", "empty stomach", "typical dosage", "Key Ingredient", "overall fitness", "optimal results", "daily activities", "longer distances", "potent medication", "cyclic AMP levels", "Increased Mobility", "Improved Blood Flow", "healthcare provider", "blood clot formation", "Improved Circulation", "cardiovascular events", "cardiovascular health", "specific health needs", "Administration Dosage", "phosphodiesterase III", "overall vascular health", "Effective Symptom Relief", "peripheral artery disease", "Enhanced Physical Activity", "consistent medication levels", "intermittent claudication symptoms", "platelet aggregation inhibition properties" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1815, "imageuri": "https://productimages.withfloats.com/actual/6669758c8c6c791fd3b357ad.png", "tileimageuri": "https://productimages.withfloats.com/tile/6669758c8c6c791fd3b357ad.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-12T10:16:41.937Z", "updatedon": "2024-06-27T06:01:08.361Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/cilostazone-100-/1815", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CILOSTAZONE 100 ", "category": "NEUROLOGY RANGE", "tags": [ "CILOSTAZONE 100", "Cilostazol 100mg price", "Cilostazol 100mg", "Cilostazol (100mg) usess", "", "Cilostazol mechanism of action", "cilostazol side effects" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "665ee8be7b387b17ecbcbde3", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": " SACUBRIGHT 200 ", "description": "SACUBRIGHT 200 \nSacubitril (97mg), Valsartan (103mg)\nSACUBRIGHT 200 is a combination medication containing two active ingredients: Sacubitril (97mg) and Valsartan (103mg). This combination is designed to provide dual inhibition of the renin-angiotensin-aldosterone system (RAAS) for the treatment of heart failure with reduced ejection fraction (HFrEF).\n\nSacubitril is a neprilysin inhibitor, while Valsartan is an angiotensin II receptor blocker (ARB). Together, they work synergistically to improve cardiovascular outcomes in patients with HFrEF by targeting different pathways involved in the pathophysiology of heart failure.\n\nNeprilysin is an enzyme responsible for the degradation of natriuretic peptides, which play a crucial role in regulating blood pressure and fluid balance. By inhibiting neprilysin, Sacubitril increases the levels of natriuretic peptides, leading to vasodilation, natriuresis, and diuresis, which helps reduce blood pressure, preload, and afterload on the heart.\n\nValsartan, as an ARB, blocks the effects of angiotensin II, a vasoconstrictor and stimulator of aldosterone secretion. By antagonizing the angiotensin II type 1 (AT1) receptors, Valsartan dilates blood vessels, reduces blood pressure, and attenuates the deleterious effects of angiotensin II on cardiac remodeling and fibrosis.\n\nSACUBRIGHT 200 is indicated for the treatment of symptomatic HFrEF in patients with New York Heart Association (NYHA) class II-IV heart failure. Clinical studies have demonstrated that this combination therapy reduces the risk of cardiovascular death and hospitalization for heart failure compared to traditional therapy with angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) alone.\n\nAs with any medication, SACUBRIGHT 200 may cause side effects, including hypotension, hyperkalemia, renal impairment, and angioedema. Patients should be monitored regularly for these adverse effects, especially during initiation and dose titration.\n\nOverall, SACUBRIGHT 200 represents an innovative approach to the management of HFrEF, offering superior efficacy and cardiovascular benefits compared to standard therapy. However, it should only be used under the supervision of a healthcare professional experienced in the management of heart failure and in accordance with established treatment guidelines.\n\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order Now\nhttps://www.sterisonline.com/product/sacubright-200-134307\n\n\n\n", "price": 740.0, "discountamount": 222.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "ARB", "risk", "RAAS", "EMAIL", "Order", "levels", "diuresis", "fibrosis", "patients", "Valsartan", "stimulator", "initiation", "angioedema", "SACUBRIGHT", "accordance", "management", "Sacubitril", "natriuresis", "degradation", "information", "supervision", "hypotension", "sterisonline", "sterispharma", "hyperkalemia", "vasodilation", "side effects", "crucial role", "CALL/WHATSAPP", "fluid balance", "blood vessels", "dose titration", "AT1) receptors", "blood pressure", "dual inhibition", "adverse effects", "pathophysiology", "hospitalization", "vasoconstrictor", "standard therapy", "renal impairment", "Clinical studies", "symptomatic HFrEF", "superior efficacy", "different pathways", "cardiac remodeling", "combination therapy", "deleterious effects", "innovative approach", "traditional therapy", "treatment guidelines", "neprilysin inhibitor", "cardiovascular death", "natriuretic peptides", "angiotensin II type 1", "aldosterone secretion", "two active ingredients", "combination medication", "cardiovascular outcomes", "cardiovascular benefits", "healthcare professional", "reduced ejection fraction", "New York Heart Association", "angiotensin receptor blockers", "angiotensin II receptor blocker", "NYHA) class II-IV heart failure", "renin-angiotensin-aldosterone system", "angiotensin-converting enzyme (ACE) inhibitors" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1279, "imageuri": "https://productimages.withfloats.com/actual/665ee8c06030c166b1a41ef3.png", "tileimageuri": "https://productimages.withfloats.com/tile/665ee8c06030c166b1a41ef3.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-04T10:13:18.717Z", "updatedon": "2024-06-04T10:13:18.717Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/-sacubright-200-/1279", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Sacubitril (97mg), Valsartan (103mg)", "category": "CARDIOLOGYRANGE", "tags": null, "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "68e7a474f3481c1f16d3b038", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Sitagliptin (50mg), Metformin Hydrochloride (500mg) & Glimepiride (2mg)", "description": "Sitagliptin 50mg, Metformin Hydrochloride 500mg & Glimepiride 2mg is a combination oral medication designed for the effective management of type 2 diabetes mellitus. This triple-action formula works synergistically to control blood glucose levels by addressing insulin resistance, enhancing insulin secretion, and regulating post-meal sugar spikes. Ideal for patients who require more than one mechanism to maintain stable blood sugar, this combination is often prescribed when monotherapy or dual therapy is insufficient.\n\nUses\n\nManagement of Type 2 Diabetes Mellitus in adults.\n\nHelps in controlling fasting and postprandial blood glucose levels.\n\nRecommended for patients whose blood sugar is not adequately controlled with a single antidiabetic medicine.\n\nCan be used as part of a comprehensive diabetes management plan, including diet and exercise.\n\nKey Benefits\n\nDual Mechanism Control:\n\nMetformin Hydrochloride reduces hepatic glucose production and improves insulin sensitivity.\n\nGlimepiride stimulates pancreatic beta cells to secrete more insulin.\n\nSitagliptin enhances incretin hormones, leading to better regulation of post-meal glucose levels.\n\nEffective Blood Sugar Management:\nHelps maintain optimal fasting and postprandial glucose levels, reducing the risk of diabetes-related complications.\n\nConvenient Combination Therapy:\nCombines three mechanisms in a single tablet, reducing the pill burden and improving patient compliance.\n\nSupports Overall Health:\nHelps prevent long-term complications such as neuropathy, nephropathy, retinopathy, and cardiovascular risks associated with diabetes.\n\nPossible Side Effects\n\nWhile generally well-tolerated, some patients may experience:\n\nGastrointestinal issues: nausea, vomiting, diarrhea, or abdominal discomfort (mainly from Metformin).\n\nHypoglycemia (low blood sugar): more likely due to Glimepiride; symptoms include dizziness, sweating, or shakiness.\n\nAllergic reactions: rash, itching, or swelling in rare cases.\n\nOther mild effects: headache, fatigue, or minor changes in taste.\n\nNote: Patients should always consult their doctor before starting this combination and report any unusual symptoms immediately.\n\nConclusion\n\nThe Sitagliptin, Metformin Hydrochloride & Glimepiride combination provides a powerful, multi-targeted approach to managing type 2 diabetes. By tackling high blood sugar from different angles, it supports better glucose control, enhances overall quality of life, and reduces the risk of diabetes-related complications. When used alongside proper diet, exercise, and medical guidance, this combination can be a cornerstone in effective diabetes management.", "price": 180.0, "discountamount": 54.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2185, "imageuri": "https://productimages.withfloats.com/actual/68e7a47b040520d37b5e6b34.png", "tileimageuri": "https://productimages.withfloats.com/tile/68e7a47b040520d37b5e6b34.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-10-09T12:03:00.012Z", "updatedon": "2025-10-09T12:03:00.012Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/sitagliptin-50mg-metformin-hydrochloride-500mg-glimepiride-2mg-/2185", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "ST GLIPTIN GM", "category": "", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "68e63e06f3481c1f16d3ae51", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Tenofovir Alafenamide 25 mg", "description": "TELAVINCE AF 25 is primarily indicated for:\n\nHypertension (High Blood Pressure): Effectively helps in lowering elevated blood pressure.\n\nCardiovascular Risk Reduction: Supports heart health and reduces the risk of heart attack, stroke, and other complications related to high blood pressure.\n\nPatients requiring combination therapy: Ideal for individuals who need more than one antihypertensive agent for optimal blood pressure control.\n\nMechanism of Action:\n\nTELAVINCE AF 25 combines two mechanisms for effective blood pressure management:\n\nTelmisartan: Blocks angiotensin II receptors, preventing blood vessel constriction and thereby reducing blood pressure.\n\n[AF Component, e.g., Amlodipine]: Relaxes blood vessels by inhibiting calcium entry into vascular smooth muscles, improving blood flow and reducing strain on the heart.\n\nThis dual-action combination provides better efficacy than single-drug therapy while maintaining a favorable safety profile.\n\nDosage and Administration:\n\nRecommended Dose: As prescribed by a healthcare professional, typically one tablet daily.\n\nRoute: Oral, with water.\n\nTiming: Can be taken with or without food, preferably at the same time each day.\n\nAdjustment: Dose may be adjusted based on individual response and tolerability.\n\nImportant: Always follow your doctor’s instructions. Do not change the dose or stop medication without medical advice.\n\nKey Benefits of TELAVINCE AF 25:\n\nEffective blood pressure control with dual-action therapy.\n\nReduces the risk of cardiovascular complications associated with hypertension.\n\nConvenient once-daily dosing for better patient adherence.\n\nWell-tolerated with minimal side effects.\n\nSuitable for long-term use under medical supervision.\n\nSafety and Precautions:\n\nInform your doctor if you have kidney disease, liver disease, or heart failure.\n\nPregnant or breastfeeding women should use only if recommended by a physician.\n\nAvoid excessive use of potassium-containing salt substitutes.\n\nRegular monitoring of blood pressure and kidney function is recommended.\n\nDo not combine with other angiotensin receptor blockers (ARBs) unless prescribed.\n\nPossible Side Effects:\n\nWhile generally well-tolerated, some patients may experience:\n\nDizziness or lightheadedness\n\nFatigue or weakness\n\nMild swelling of ankles or feet\n\nNausea or headache\n\nSeek immediate medical attention if you experience:\n\nSevere allergic reactions\n\nSwelling of face, lips, or throat\n\nDifficulty breathing\n\nStorage Instructions:\n\nStore in a cool, dry place away from sunlight.\n\nKeep out of reach of children and pets.\n\nDo not use after the expiry date mentioned on the package.\n\nWhy Choose TELAVINCE AF 25:\n\nDeveloped by Steris Healthcare Pvt. Ltd, a trusted pharmaceutical company.\n\nEnsures quality, safety, and efficacy in every tablet.\n\nDesigned for patient convenience with once-daily dosing.\n\nBacked by clinical research for effective hypertension management.\n\nDisclaimer:\n\nThe information provided here is for educational purposes only. TELAVINCE AF 25 should be used only under medical supervision. Consult your healthcare provider for personalized advice. Side effects may vary from person to person.\n\n", "price": 1566.0, "discountamount": 470.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2184, "imageuri": "https://productimages.withfloats.com/actual/68e63e0d931b4d6a7310ae2a.png", "tileimageuri": "https://productimages.withfloats.com/tile/68e63e0d931b4d6a7310ae2a.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-10-08T10:33:42.289Z", "updatedon": "2025-10-08T10:35:29.464Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/tenofovir-alafenamide-25-mg/2184", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Steris Healthcare Pvt. Ltd.", "category": "GENERAL RANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "68e63c17e7475f0f453d4b6e", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Tenofovir (300mg), Emtricitabine (200mg) & Efavirenz (600 mg)", "description": "TELAVINCE EM is primarily indicated for the management of:\n\nHypertension (High Blood Pressure): Helps in reducing elevated blood pressure effectively.\n\nCardiovascular Risk Reduction: Supports heart health and reduces the risk of stroke, heart attack, and related complications.\n\nPatients requiring combination therapy: Suitable for individuals who need more than one antihypertensive for better blood pressure control.\n\nMechanism of Action:\n\nTELAVINCE EM works through a dual mechanism to control blood pressure:\n\nTelmisartan: Blocks angiotensin II receptors, preventing blood vessel constriction and reducing blood pressure.\n\n[EM Component, e.g., Amlodipine]: Relaxes blood vessels by inhibiting calcium entry into vascular smooth muscles, improving blood flow and reducing strain on the heart.\n\nThe combination ensures better efficacy than monotherapy while maintaining a favorable safety profile.\n\nDosage and Administration:\n\nRecommended Dose: As prescribed by a healthcare professional, typically one tablet daily.\n\nRoute: Oral administration with water.\n\nTiming: Can be taken with or without food, preferably at the same time each day.\n\nAdjustment: Dose may be modified based on individual response and tolerability.\n\nImportant: Always follow your doctor’s instructions. Do not alter the dose or stop medication without medical advice.\n\nKey Benefits of TELAVINCE EM:\n\nEffective blood pressure control with dual-action therapy.\n\nReduces risk of cardiovascular events associated with hypertension.\n\nConvenient once-daily dosing improves patient compliance.\n\nWell-tolerated with a low incidence of side effects.\n\nSuitable for long-term use under medical supervision.\n\nSafety and Precautions:\n\nInform your doctor if you have kidney disease, liver disease, or heart failure.\n\nPregnant or breastfeeding women should avoid use unless advised by a physician.\n\nAvoid excessive salt substitutes containing potassium.\n\nRegular blood pressure and kidney function monitoring is recommended.\n\nDo not use in combination with other angiotensin receptor blockers (ARBs) unless prescribed.\n\nPossible Side Effects:\n\nAlthough TELAVINCE EM is generally well-tolerated, some patients may experience:\n\nDizziness or lightheadedness\n\nFatigue or weakness\n\nMild swelling in ankles or feet\n\nNausea or headache\n\nSeek immediate medical attention if you experience severe side effects such as difficulty breathing, swelling of face or throat, or severe allergic reactions.\n\nStorage Instructions:\n\nStore in a cool, dry place away from direct sunlight.\n\nKeep out of reach of children and pets.\n\nDo not use after the expiry date mentioned on the package.\n\nWhy Choose TELAVINCE EM:\n\nDeveloped by Steris Healthcare Pvt. Ltd, a trusted name in pharmaceutical excellence.\n\nEnsures quality, safety, and efficacy in every tablet.\n\nDesigned for optimal patient compliance with convenient dosing.\n\nBacked by clinical research for managing hypertension effectively.\n\nDisclaimer:\n\nThe information provided here is intended for educational purposes only. TELAVINCE EM should be used only under medical supervision. Consult your healthcare provider for personalized advice. Side effects may vary from person to person.", "price": 4715.0, "discountamount": 1415.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2183, "imageuri": "https://productimages.withfloats.com/actual/68e63c1a4302b5c8207e2858.png", "tileimageuri": "https://productimages.withfloats.com/tile/68e63c1a4302b5c8207e2858.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-10-08T10:25:27.075Z", "updatedon": "2025-10-08T10:36:46.57Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/tenofovir-300mg-emtricitabine-200mg-efavirenz-600-mg-/2183", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Steris Healthcare Pvt. Ltd.", "category": "GENERAL RANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "68d51d9a26579f4bc195771a", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Glimepiride IP1 mg, Voglibose IP 0.2 MG & Metformin Hydrochloride IP 500 mg ", "description": "GLIMITERIS MV1 0.2 is an advanced fixed-dose combination (FDC) medication designed for adults with Type 2 Diabetes Mellitus (T2DM) who require more than lifestyle modifications or single/dual therapy to maintain optimal blood sugar levels. This innovative formulation brings together the power of three well-established antidiabetic agents—Glimepiride (1 mg), Voglibose (0.2 mg), and Metformin Hydrochloride SR (500 mg)—to provide comprehensive glycemic control.\n\nIt is particularly effective for patients struggling with postprandial hyperglycemia, fasting glucose regulation, and HbA1c reduction, making it a preferred choice in cases of poorly controlled diabetes.\n\n \n\nMechanism of Action\nThe therapeutic benefit of GLIMITERIS MV1 0.2 comes from the unique synergy of its three components, each targeting different aspects of glucose metabolism:\n\n1. Glimepiride (1 mg) – Sulfonylurea\nStimulates insulin secretion by activating pancreatic beta cells.\n\nProvides a long-lasting effect with comparatively lower hypoglycemia risk than older sulfonylureas.\n\nHelps reduce both fasting and postprandial glucose levels.\n\n2. Voglibose (0.2 mg) – Alpha-Glucosidase Inhibitor\nDelays the breakdown and absorption of carbohydrates in the intestine.\n\nMinimizes post-meal glucose spikes (PPBG).\n\nActs locally in the gut and has minimal systemic absorption, which reduces systemic side effects.\n\n3. Metformin Hydrochloride SR (500 mg) – Biguanide\nDecreases hepatic glucose production (gluconeogenesis).\n\nImproves peripheral insulin sensitivity, enhancing glucose uptake in muscles.\n\nDoes not cause hypoglycemia on its own.\n\nThe sustained-release (SR) formulation ensures extended control and reduces gastrointestinal side effects.\n\n \n\nIndications\nGLIMITERIS MV1 0.2 is indicated for:\n\nAdults with Type 2 Diabetes Mellitus.\n\nPatients inadequately controlled with monotherapy or dual therapy.\n\nManagement of fasting and postprandial hyperglycemia.\n\nLong-term HbA1c reduction as part of a comprehensive diabetes care plan.\n\n \n\nKey Benefits\n✅ Comprehensive Blood Sugar Control – Acts on fasting, post-meal, and long-term HbA1c levels.\n✅ Postprandial Spike Management – Voglibose effectively controls carbohydrate-induced sugar surges.\n✅ Reduced Pill Burden – Combines three medicines into a single tablet.\n✅ Lower Hypoglycemia Risk – Metformin and Voglibose balance out Glimepiride’s insulin-secreting effect.\n✅ Weight Management Support – Metformin may promote modest weight loss or prevent weight gain.\n✅ Improved Tolerability – SR formulation of Metformin enhances gastrointestinal comfort.\n\n \n\nDosage and Administration\nRecommended dose: One tablet once or twice daily with meals, or as directed by the physician.\n\nAdministration tips:\n\nTake with the first bite of a main meal to maximize Voglibose’s effect.\n\nSwallow whole with water; do not crush or chew the SR tablet.\n\nDose adjustments: Based on blood sugar monitoring, clinical response, and renal/hepatic function.\n\n \n\nContraindications\nGLIMITERIS MV1 0.2 is not suitable for patients with:\n\nType 1 diabetes or diabetic ketoacidosis.\n\nSevere renal impairment (eGFR <30 mL/min/1.73 m²).\n\nHepatic dysfunction.\n\nSevere gastrointestinal diseases.\n\nHistory of lactic acidosis.\n\nHypersensitivity to Glimepiride, Voglibose, or Metformin.\n\nPregnancy and lactation (unless strictly advised by a physician).\n\n \n\nWarnings and Precautions\nHypoglycemia: Risk is higher when combined with other antidiabetics or with missed meals.\n\nLactic Acidosis: A rare but life-threatening effect of Metformin—renal function monitoring is essential.\n\nGI Side Effects: Voglibose and Metformin may cause bloating, flatulence, or diarrhea (usually temporary).\n\nVitamin B12 Monitoring: Long-term Metformin use may reduce B12 absorption.\n\nLiver and Kidney Function: Regular monitoring is recommended for safe long-term use.\n\n \n\nAdverse Effects\nCommon:\nGlimepiride: Mild hypoglycemia, dizziness, slight weight gain.\n\nVoglibose: Gas, abdominal discomfort, mild diarrhea.\n\nMetformin SR: Nausea, bloating, metallic taste, loose stools.\n\nRare but Serious:\nLactic acidosis (from Metformin).\n\nSevere hypoglycemia (especially if meals are skipped).\n\nAllergic reactions such as rash, itching, or swelling.\n\nElevated liver enzymes.\n\nSeek medical attention if symptoms such as rapid breathing, confusion, severe fatigue, or muscle pain occur.\n\n \n\nDrug Interactions\nIncreased hypoglycemia risk: With insulin, beta-blockers, and sulfonylureas.\n\nReduced Metformin efficacy: With corticosteroids, estrogens, and diuretics.\n\nLactic acidosis risk: Higher with alcohol or iodinated contrast agents. 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