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{ "products": [ { "_id": "69942f823b20a66d9dcf9458", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Indacaterol Maleate and Glycopyrronium Bromide", "description": "GLYCOPRESS INDUS™ is a modern dual bronchodilator therapy formulated with Indacaterol Maleate and Glycopyrronium Bromide, designed for the long-term maintenance treatment of chronic obstructive pulmonary disease (COPD). This advanced inhalation formulation combines two complementary mechanisms of action to deliver sustained airway relaxation, improved lung function, and enhanced breathing comfort.\n\nCOPD is a progressive respiratory condition characterized by airflow limitation, chronic inflammation, and episodes of breathlessness. Effective management requires consistent bronchodilation to keep the airways open and reduce daily symptoms. GLYCOPRESS INDUS™ addresses this need through a once-daily maintenance approach that targets airway narrowing through dual pharmacological pathways.\n\nManufactured under strict quality standards, GLYCOPRESS INDUS™ ensures reliable dosing, stability, and optimal pulmonary delivery when used with the recommended inhalation device. It is intended for regular use and not for the treatment of sudden breathing emergencies.\n\nComposition and Mechanism of Action\n\nGLYCOPRESS INDUS™ combines two long-acting bronchodilators:\n\n1. Indacaterol Maleate (Long-Acting Beta2-Agonist – LABA)\n\nIndacaterol stimulates beta2-adrenergic receptors located in the smooth muscles of the airways. Activation of these receptors causes the muscles to relax, resulting in bronchodilation. This effect:\n\nReduces airway resistance\n\nImproves airflow\n\nDecreases breathlessness\n\nSupports 24-hour bronchodilation\n\nIndacaterol is known for its rapid onset and prolonged duration of action, making it effective for once-daily therapy.\n\n2. Glycopyrronium Bromide (Long-Acting Muscarinic Antagonist – LAMA)\n\nGlycopyrronium blocks muscarinic receptors in the bronchial smooth muscles. These receptors normally respond to acetylcholine, which causes airway constriction. By inhibiting this response, glycopyrronium:\n\nPrevents bronchospasm\n\nReduces airway tightening\n\nPromotes sustained airway relaxation\n\nDual-Action Advantage\n\nThe combination of LABA and LAMA in GLYCOPRESS INDUS™ provides enhanced bronchodilation compared to either agent alone. While indacaterol actively relaxes airway muscles, glycopyrronium prevents them from tightening. This complementary action ensures comprehensive and sustained airway management.\n\nIndications and Uses\n\nGLYCOPRESS INDUS™ is indicated for:\n\nMaintenance treatment of chronic obstructive pulmonary disease (COPD)\n\nChronic bronchitis management\n\nEmphysema management\n\nLong-term airflow limitation therapy\n\nIt is important to understand that GLYCOPRESS INDUS™:\n\nIs not a rescue inhaler\n\nShould not be used for sudden acute bronchospasm\n\nIs not intended for primary asthma treatment unless prescribed by a physician\n\nPatients should always keep a short-acting bronchodilator available for emergency relief.\n\nKey Benefits of GLYCOPRESS INDUS™\n1. Once-Daily Dosing Convenience\n\nGLYCOPRESS INDUS™ is formulated for once-daily administration, improving adherence and simplifying treatment routines.\n\n2. Dual Bronchodilation for Superior Airway Control\n\nThe LABA + LAMA combination provides broader and more effective airway relaxation compared to single-agent therapy.\n\n3. Rapid Onset with Sustained Effect\n\nIndacaterol provides quick bronchodilation, while glycopyrronium maintains airway openness for up to 24 hours.\n\n4. Improved Lung Function\n\nRegular use can enhance lung performance parameters, such as improved airflow measurements and reduced air trapping.\n\n5. Reduced Breathlessness\n\nPatients may experience decreased shortness of breath during physical activities, leading to greater independence.\n\n6. Lower Frequency of COPD Exacerbations\n\nConsistent airway maintenance can help reduce the likelihood of flare-ups and hospital visits.\n\n7. Enhanced Quality of Life\n\nBetter breathing control contributes to improved sleep, increased exercise tolerance, and overall well-being.\n\nDosage and Administration\n\nGLYCOPRESS INDUS™ should be used exactly as prescribed by a healthcare professional.\n\nGeneral Administration Guidelines:\n\nUse once daily at the same time each day.\n\nInhale using the provided inhalation device.\n\nDo not swallow capsules (if capsule-based system).\n\nDo not exceed the recommended dose.\n\nFollow inhaler technique instructions carefully.\n\nProper inhalation technique is essential for effective drug delivery. Healthcare providers should demonstrate correct usage during initial prescription.\n\nPossible Side Effects\n\nWhile GLYCOPRESS INDUS™ is generally well tolerated, some individuals may experience side effects.\n\nCommon Side Effects\n\nDry mouth\n\nCough\n\nThroat irritation\n\nHeadache\n\nNasal congestion\n\nMild tremor\n\nDizziness\n\nThese symptoms are often mild and may diminish with continued use.\n\nCardiovascular Effects\n\nDue to the beta2-agonist component (indacaterol), some patients may experience:\n\nIncreased heart rate\n\nPalpitations\n\nMild fluctuations in blood pressure\n\nPatients with pre-existing heart conditions should consult their physician before starting therapy.\n\nAnticholinergic Effects (from Glycopyrronium)\n\nDifficulty urinating\n\nBlurred vision\n\nWorsening of narrow-angle glaucoma\n\nIndividuals with urinary retention or glaucoma should use caution.\n\nRare but Serious Reactions\n\nParadoxical bronchospasm (worsening breathing immediately after inhalation)\n\nSevere allergic reactions\n\nSignificant cardiac rhythm disturbances\n\nImmediate medical attention should be sought if severe reactions occur.\n\nPrecautions and Warnings\n\nBefore starting GLYCOPRESS INDUS™, inform your healthcare provider if you have:\n\nCardiovascular disease\n\nArrhythmias\n\nHypertension\n\nHyperthyroidism\n\nDiabetes\n\nSeizure disorders\n\nGlaucoma\n\nProstate enlargement\n\nKidney impairment\n\nDrug Interactions\n\nCaution is required when using:\n\nOther long-acting beta2-agonists\n\nOther anticholinergic medications\n\nBeta-blockers\n\nDiuretics\n\nCertain antidepressants (e.g., MAO inhibitors)\n\nAlways provide a complete list of medications and supplements to your healthcare provider.\n\nWho Should Use GLYCOPRESS INDUS™?\n\nGLYCOPRESS INDUS™ is ideal for:\n\nAdults with moderate to severe COPD\n\nPatients not adequately controlled on single bronchodilator therapy\n\nIndividuals seeking a once-daily maintenance inhaler\n\nPatients requiring dual bronchodilation for improved symptom control\n\nIt is not typically recommended for pediatric patients unless specifically directed by a healthcare professional.\n\nIntegrating GLYCOPRESS INDUS™ into COPD Management\n\nFor optimal results, GLYCOPRESS INDUS™ should be part of a comprehensive COPD management plan that includes:\n\nSmoking cessation\n\nPulmonary rehabilitation programs\n\nRegular physical activity\n\nBalanced nutrition\n\nScheduled medical follow-ups\n\nAdherence to therapy and routine monitoring significantly improve long-term outcomes.\n\nStorage Instructions\n\nStore at room temperature\n\nProtect from moisture and direct sunlight\n\nKeep in original packaging until use\n\nKeep out of reach of children\nConclusion\nGLYCOPRESS INDUS™ (Indacaterol Maleate + Glycopyrronium Bromide) is a powerful dual bronchodilator designed to provide sustained airway control in individuals living with chronic obstructive pulmonary disease. By combining a long-acting beta2-agonist and a long-acting muscarinic antagonist, it offers comprehensive bronchodilation through two complementary pathways.", "price": 703.0, "discountamount": 211.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2308, "imageuri": "https://productimages.withfloats.com/actual/69942f8410196f5f212c916f.png", "tileimageuri": "https://productimages.withfloats.com/tile/69942f8410196f5f212c916f.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-02-17T09:06:10.4Z", "updatedon": "2026-02-17T09:06:10.4Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/indacaterol-maleate-and-glycopyrronium-bromide/2308", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "GLYCOPRESS INDUS", "category": "ASTHMARANGE", "tags": [ "indacaterol maleate and glycopyrronium bromide inhalation powder dosage", "indacaterol maleate and glycopyrronium bromide dry powder inhaler use", "indacaterol maleate and glycopyrronium bromide COPD maintenance therapy", "indacaterol maleate and glycopyrronium bromide combination therapy side effects", "indacaterol maleate and glycopyrronium bromide unit dose inhalation capsules", "indacaterol maleate and glycopyrronium bromide nebulization instructions", "what is indacaterol maleate and glycopyrronium bromide used for", "how to use indacaterol maleate and glycopyrronium bromide inhaler", "buy indacaterol maleate and glycopyrronium bromide inhaler online" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6958e93754131a1a1c764ad4", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Aspirin IP 75 mg, Atorvastatin Calcium IP 40 mg", "description": "Introduction\n\nCardiovascular diseases remain one of the leading causes of illness and mortality worldwide, often developing silently over years before showing noticeable symptoms. Conditions such as heart attacks, strokes, and blocked arteries are frequently linked to two major factors: high cholesterol levels and abnormal blood clot formation. Managing these risks early and effectively is crucial for long-term heart health.\n\nATOVASTRIN AV 40/75 is a scientifically formulated combination medicine that brings together two well-established and widely trusted cardiovascular agents—Aspirin IP 75 mg and Atorvastatin Calcium IP 40 mg. This dual-action therapy is designed to protect the heart and blood vessels by addressing both clot formation and cholesterol management in a single tablet.\n\nBy combining these two essential medicines, ATOVASTRIN AV 40/75 simplifies treatment, improves patient compliance, and provides comprehensive cardiovascular protection for individuals at risk of heart-related complications.\n\nComposition\n\nEach film-coated tablet contains:\n\nAspirin IP 75 mg\n\nAtorvastatin Calcium IP equivalent to Atorvastatin 40 mg\n\nBrand Name: ATOVASTRIN AV 40/75\nDosage Form: Oral tablet\n\nHow ATOVASTRIN AV 40/75 Works\n\nATOVASTRIN AV 40/75 works through a complementary and synergistic mechanism, targeting two major contributors to cardiovascular disease.\n\nRole of Aspirin IP 75 mg\n\nAspirin at a low dose acts as an antiplatelet agent. It prevents platelets in the blood from sticking together and forming clots. Blood clots can block arteries supplying the heart or brain, leading to heart attacks or strokes. By reducing platelet aggregation, Aspirin helps maintain smooth blood flow.\n\nRole of Atorvastatin Calcium IP 40 mg\n\nAtorvastatin belongs to the statin class of medicines. It works by inhibiting an enzyme involved in cholesterol production in the liver. This results in:\n\nReduced levels of LDL (bad cholesterol)\n\nModerate increase in HDL (good cholesterol)\n\nLower triglyceride levels\n\nTogether, these effects slow the progression of plaque buildup in arteries and reduce the risk of cardiovascular events.\n\nUses of ATOVASTRIN AV 40/75\n1. Prevention of Heart Attack\n\nATOVASTRIN AV 40/75 is commonly prescribed to patients with a history of heart attack or those at high risk, helping prevent future cardiac events.\n\n2. Stroke Prevention\n\nBy preventing clot formation and improving lipid profiles, this combination reduces the risk of ischemic stroke, particularly in high-risk individuals.\n\n3. Management of High Cholesterol\n\nAtorvastatin effectively lowers cholesterol levels, especially LDL cholesterol, which is a major contributor to artery blockage.\n\n4. Post-Angioplasty or Bypass Care\n\nPatients who have undergone angioplasty, stent placement, or bypass surgery often receive this combination to prevent clot formation and recurrence of blockages.\n\n5. Coronary Artery Disease (CAD)\n\nATOVASTRIN AV 40/75 plays a key role in the long-term management of coronary artery disease by protecting blood vessels and improving circulation.\n\nKey Benefits of ATOVASTRIN AV 40/75\n1. Dual Cardiovascular Protection\n\nThis combination offers both antiplatelet and lipid-lowering effects, providing broad-spectrum heart protection in a single tablet.\n\n2. Reduces Risk of Blood Clots\n\nLow-dose Aspirin minimizes the chances of clot formation, ensuring uninterrupted blood flow to vital organs.\n\n3. Lowers Bad Cholesterol Levels\n\nAtorvastatin significantly reduces LDL cholesterol, which helps prevent plaque buildup in arteries.\n\n4. Slows Progression of Atherosclerosis\n\nBy improving cholesterol balance and preventing clots, the medicine slows the narrowing and hardening of arteries.\n\n5. Improves Treatment Compliance\n\nA single combination tablet reduces pill burden, making it easier for patients to follow long-term therapy.\n\n6. Suitable for Long-Term Use\n\nWhen taken under medical supervision, ATOVASTRIN AV 40/75 is effective and safe for extended use.\n\n7. Proven Clinical Ingredients\n\nBoth Aspirin and Atorvastatin are extensively researched and widely recommended in cardiovascular guidelines.\n\nDosage and Administration\n\nUsually taken once daily, preferably at the same time each day\n\nCan be taken with or after food to reduce stomach irritation\n\nSwallow the tablet whole with water; do not crush or chew\n\nThe exact dosage and duration depend on the patient’s medical condition, cholesterol levels, and risk factors, as determined by a healthcare professional.\n\nPossible Side Effects of ATOVASTRIN AV 40/75\n\nMost patients tolerate ATOVASTRIN AV 40/75 well. However, some side effects may occur.\n\nCommon Side Effects\n\nMild stomach pain\n\nNausea\n\nIndigestion\n\nHeadache\n\nMuscle aches\n\nLess Common Side Effects\n\nDizziness\n\nIncreased liver enzymes\n\nDiarrhea or constipation\n\nFatigue\n\nRare but Serious Side Effects\n\nGastrointestinal bleeding (associated with Aspirin)\n\nSevere muscle pain or weakness\n\nLiver function abnormalities\n\nAllergic reactions\n\nPatients are advised to report unusual muscle pain, dark urine, or persistent stomach discomfort to their doctor promptly.\n\nPrecautions and Warnings\n\nLiver Disease: Use cautiously in patients with liver disorders; regular liver function tests are recommended.\n\nBleeding Risk: Aspirin increases bleeding tendency; inform your doctor before surgery or dental procedures.\n\nAlcohol Intake: Excessive alcohol consumption should be avoided.\n\nPregnancy & Breastfeeding: Not recommended unless clearly prescribed by a doctor.\n\nDrug Interactions: Inform your physician about all other medications, including painkillers, anticoagulants, or herbal supplements.\n\nWho Should Avoid ATOVASTRIN AV 40/75?\n\nPatients with active liver disease\n\nIndividuals with bleeding disorders\n\nThose allergic to Aspirin or Atorvastatin\n\nPregnant women, unless advised by a physician\n\nStorage Instructions\n\nStore below 25°C\n\nProtect from moisture and direct sunlight\n\nKeep out of reach of children\n\nDo not use after the expiry date\n\nConclusion\nATOVASTRIN AV 40/75 (Aspirin IP 75 mg + Atorvastatin Calcium IP 40 mg) is a powerful and reliable combination therapy designed to address two of the most critical risk factors in cardiovascular disease—blood clot formation and high cholesterol levels. By offering comprehensive heart protection in a single tablet, it simplifies long-term treatment while enhancing patient compliance.", "price": 267.0, "discountamount": 81.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2263, "imageuri": "https://productimages.withfloats.com/actual/6958e9c81a64c8a440502a4f.png", "tileimageuri": "https://productimages.withfloats.com/tile/6958e9c81a64c8a440502a4f.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-03T10:02:31.638Z", "updatedon": "2026-01-23T06:45:15.28Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/aspirin-ip-75-mg-atorvastatin-calcium-ip-40-mg/2263", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "ATOVASTRIN AV 40/75", "category": "CARDIOLOGYRANGE", "tags": [ "aspirin 75", "tab aspirin 75", "aspirin 75 mg uses", "aspirin 75 mg tablet uses", "Moderate increase in HDL (good cholesterol)", "heart attack .", "helping prevent future cardiac events.", "Stroke Prevention.", "bypass surgery often receive this combination .", "Lowers Bad Cholesterol Levels", "atorvastatin calcium 40 mg", "atorvastatin calcium 40 mg tablet", "atorvastatin calcium 40 mg used for.", "atorvastatin calcium 40 mg price.", "atorvastatin calcium 40 mg uses", "atorvastatin calcium 40", "how much calcium is in atorvastatin calcium 40 mg.", "what is atorvastatin calcium 40 mg used for.", "atorvastatin calcium 40 mg side effects" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6958dbfa1063d98b1e8f2fe1", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Benidipine 4mg", "description": "BENIPRIME 4, containing Benidipine 4 mg, offers effective management for high blood pressure and related heart conditions. This calcium channel blocker helps relax blood vessels to improve blood flow and reduce strain on the heart. Patients often find it reliable for daily control of hypertension symptoms.\n\nWhat is BENIPRIME 4?\nBENIPRIME 4 is a branded tablet from Steris Healthcare Pvt Ltd, featuring 4 mg of Benidipine as the active ingredient. Benidipine belongs to the dihydropyridine class of calcium channel blockers, designed specifically for cardiovascular health. Each tablet delivers a precise dose in a user-friendly form, typically packaged in strips of 10 for convenient use. Manufactured under strict quality standards, it targets essential needs in hypertension care, making it a staple in many treatment plans across India.\n​\n\nThis medication stands out due to its triple action on L-type, N-type, and T-type calcium channels, providing broader vascular protection compared to some other blockers. Doctors prescribe it for adults dealing with persistent high blood pressure or chest pain, often starting at this 4 mg strength for balanced efficacy. Unlike generic options, BENIPRIME 4 ensures consistent absorption and formulation tailored for Indian patients, with pricing around Rs 62-89 per strip after discounts.\n​\n\nHow BENIPRIME 4 Works\nBenidipine in BENIPRIME 4 blocks calcium entry into smooth muscle cells of blood vessels and heart muscles. This action causes vasodilation, widening arteries to lower resistance and ease blood flow. By reducing systolic and diastolic pressure, it lightens the heart's workload without drastically slowing the heartbeat.\n​\n\nThe unique blockade of multiple calcium channels also boosts nitric oxide production, offering antioxidant effects and protection against artery hardening. This sustained mechanism provides 24-hour control, ideal for once-daily dosing after breakfast. Over time, it may even reduce urinary protein and triglycerides, supporting kidney and metabolic health in hypertensives.\n​\n\nKey Uses of BENIPRIME 4\nBENIPRIME 4 primarily treats essential hypertension, helping prevent strokes, heart attacks, and kidney damage. It effectively manages angina pectoris by enhancing coronary blood supply, reducing chest pain episodes during activity.\n​\n\nPhysicians also use it for renal parenchymal hypertension, where kidney issues elevate blood pressure. In emergencies like hypertensive crises or subarachnoid hemorrhage, higher doses prove beneficial, though 4mg serves as maintenance. For arrhythmia or anal fissures linked to vascular strain, it offers supportive relief.\n​\n\nLowers high blood pressure in adults, including severe cases with dose adjustments.\n​\n\nEases angina symptoms, improving exercise tolerance and daily life quality.\n​\n\nProtects renal function in proteinuric patients by stabilizing vessels.\n​\n\nDosage and Administration\nTake BENIPRIME 4 as 4 mg once daily, swallowed whole after a meal to minimize stomach upset. Doctors may adjust to 2-8mg based on response, age, or kidney/liver status, never exceeding 8 mg daily without monitoring. Consistency in timing ensures steady levels for optimal pressure control.\n​\n\nMissed doses require prompt intake if remembered soon, but skip if near the next one—avoid doubles. Pair with lifestyle changes like low-salt diets and exercise for best results. Always consult for personalization, especially in elderly or comorbid patients.\n​\n\nKey Benefits\nBENIPRIME 4 excels in long-term blood pressure reduction, with studies showing sustained drops in brachial-ankle pulse wave velocity beyond mere pressure effects. It protects the heart and kidneys through anti-sclerotic and antioxidant actions, lowering cardiovascular event risks.\n​\n\nPatients experience fewer angina attacks, better endurance, and improved quality of life. The once-daily regimen boosts adherence, while vascular selectivity minimizes reflex tachycardia common in other blockers. Clinical data indicate reduced C-reactive protein and aldosterone, curbing inflammation and fibrosis.\n​\n\nBenefit\tDescription\tSupporting Evidence\nBP Control\tReduces systolic/diastolic pressure effectively over 24 hours \n​\tLong-term studies show persistent effects post-treatment \n​\nHeart Protection\tImproves coronary flow, cuts angina frequency \n​\tMyocardial protection via NO stimulation \n​\nRenal Support\tLowers proteinuria, aids kidney hypertension \n​\tAnti-oxidative vascular benefits \n​\nAdherence Ease\tOnce-daily dosing with sustained release \n​\tHigh membrane affinity for lasting action \n​\nAdditional perks include potential triglyceride reduction and osteoblast stimulation for bone health in hypertensives.\n\nPotential Side Effects\nMost users tolerate BENIPRIME 4 well, with mild, transient effects resolving spontaneously. Common issues include headache, dizziness, flushing, ankle swelling, palpitations, fatigue, nausea, and sleepiness.\n​\n\nLess frequent are constipation, abdominal pain, tinnitus, shoulder stiffness, urinary frequency, or elevated liver enzymes. Rare serious reactions involve severe hypotension, rash, itching, or allergic responses—seek immediate care if these arise. Monitor blood pressure during initiation to avoid drops.\n\nHeart-related: Palpitations, chest pressure\n​\n\nNervous system: Dizziness, headache\n\nSkin/Vascular: Flushing, edema.\n\nGI: Nausea, constipation\n​\n\nLiver/kidney patients need caution; inform doctors of history.\n\n\nPrecautions and Interactions\nAvoid in hypotension, severe aortic stenosis, or hypersensitivity to dihydropyridines. Use cautiously in liver/kidney impairment, pregnancy, or breastfeeding—benefits must outweigh risks. Grapefruit juice may amplify effects; limit alcohol.\n​\n\nIt interacts with beta-blockers, digoxin, or CYP3A4 inhibitors like ketoconazole, potentially enhancing hypotension. Regular monitoring of BP, electrolytes, and renal function is advised during therapy. Abrupt stop may rebound pressure; taper under guidance.\n​\nConclusion\nBENIPRIME 4 with Benidipine 4 mg empowers reliable hypertension and angina control through innovative calcium channel action. Balancing potent benefits like organ protection and ease of use against manageable side effects, it fits seamlessly into modern cardiac care. Consult healthcare providers for tailored integration with lifestyle for lasting heart health. ", "price": 89.0, "discountamount": 27.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2261, "imageuri": "https://productimages.withfloats.com/actual/6958dbfc615a7d157715572f.jpg", "tileimageuri": "https://productimages.withfloats.com/tile/6958dbfc615a7d157715572f.jpg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-03T09:06:02.841Z", "updatedon": "2026-01-03T09:06:02.841Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/benidipine-4mg/2261", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "BENIPRIME 4", "category": "CARDIOLOGYRANGE", "tags": [ "benidipine 4mg", "benidipine 4mg tab", "benidipine hydrochloride uses.", "benidipine.", "benidipine 4 mg", "benidipine 4", "benidipine maximum dose", "benidipine 4 mg uses.", "benidipine price" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6948e738796e72bd2659934b", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "micronized purified flavonoid fraction", "description": "Product Name: FLAVOSHIELD 500\nActive Ingredients: Micronized Purified Flavonoid Fraction (MPFF) 500mg, containing Diosmin 450mg and Hesperidin 50mg.\nPresentation: Oral Tablets\n\nUnveiling FLAVOSHIELD 500: A Deep Dive into Advanced Venous and Vascular Wellness\nIn the intricate network of the human circulatory system, veins perform the silent, relentless task of returning blood to the heart against gravity. When this system faces strain, it can manifest through discomfort, heaviness, and visible changes that impact both physical well-being and quality of life. Enter FLAVOSHIELD 500, a sophisticated pharmaceutical-grade formulation designed to fortify venous health at its core. Powered by a Micronized Purified Flavonoid Fraction (MPFF)—a precise blend of 450mg Diosmin and 50mg Hesperidin—FLAVOSHIELD 500 represents a pinnacle in venoactive therapy. This comprehensive description explores the product, its mechanism, multifaceted uses, key benefits, safety profile, and its role in a holistic health strategy.\n\nWhat is FLAVOSHIELD 500? The Science of MPFF\nFLAVOSHIELD 500 is not a simple herbal supplement; it is a clinically researched, standardized medical treatment. Its active core, the Micronized Purified Flavonoid Fraction, is derived from citrus fruits but undergoes a specialized purification and micronization process. This technological advancement is crucial:\n\nPurification: Ensures a consistent, high-potency concentration of the active flavonoid molecules, Diosmin and Hesperidin, free from plant impurities.\nMicronization: Reduces the particle size of the flavonoids dramatically, increasing their surface area. This leads to significantly enhanced absorption in the gastrointestinal tract, ensuring that a much higher percentage of the active dose reaches the bloodstream and, ultimately, the target venous tissues. Compared to non-micronized diosmin, MPFF offers up to 30% greater bioavailability, making FLAVOSHIELD 500 a more effective and reliable choice.\nThis synergy of Diosmin and Hesperidin works on multiple physiological pathways to restore venous tone and capillary integrity.\n\nPrimary Uses and Therapeutic Applications\nFLAVOSHIELD 500 is indicated for the management of various stages of chronic venous disorders and related conditions:\n\nChronic Venous Disease (CVD) & Venous Insufficiency: This is the primary use. It alleviates the distressing symptoms stemming from weakened vein walls and faulty valves in the legs. These include:\n\nHeaviness and Fatigue: The pervasive feeling of weight and tiredness in the legs, especially after prolonged standing or sitting.\nPain and Aching: Dull, throbbing, or cramping pain that improves with elevation.\nSwelling (Edema): Reduction of ankle and lower leg swelling caused by fluid leakage from capillaries.\nNocturnal Cramps: Relief from painful muscle spasms that often occur at night.\nHemorrhoidal Disease (Acute and Chronic): MPFF is a cornerstone in hemorrhoid management. It treats acute hemorrhoidal attacks by reducing bleeding, pain, and discharge. For chronic cases, it helps prevent recurrences by decreasing capillary fragility and inflammation in the anal venous plexus.\n\nPost-Phlebitic Syndrome: Following deep vein thrombosis (DVT), patients often suffer from chronic leg swelling, pain, and skin changes. FLAVOSHIELD 500 can be part of the management plan to improve microcirculation and reduce symptoms.\n\nSupport Post-Sclerotherapy or Surgical Procedures: It is commonly used after vein stripping, laser ablation, or sclerotherapy to support healing, reduce postoperative swelling and bruising, and help consolidate results.\n\nKey Benefits and Mechanism of Action: The Multi-Target Approach\nThe efficacy of FLAVOSHIELD 500 stems from its multi-faceted pharmacological actions on the venous and lymphatic systems:\n\nVenotonic Action: It increases venous tone and elasticity by promoting the contraction of smooth muscle in the vein walls. This helps veins propel blood more efficiently upward, reducing pooling and pressure. Think of it as “tightening” slackened venous structures.\n\nCapillary-Protective & Anti-Inflammatory Effects: It strengthens capillary walls (reduces capillary permeability) and inhibits the release of inflammatory mediators (like prostaglandins and leukotrienes). This dual action minimizes the leakage of fluid, proteins, and inflammatory cells into surrounding tissues, thereby directly addressing edema (swelling) and inflammation. This is particularly vital in hemorrhoidal tissue.\n\nLymphatic Enhancement: FLAVOSHIELD 500 has been shown to increase lymphatic drainage by boosting the frequency and intensity of lymphatic contractions. This provides an additional route for removing excess interstitial fluid and proteins, further reducing swelling.\n\nAntioxidant Activity: The flavonoids scavenge harmful free radicals, protecting venous and capillary endothelial cells from oxidative stress, which is a contributing factor in chronic venous disease.\n\nImprovement of Microcirculation: By reducing blood viscosity and inhibiting red blood cell aggregation, it improves blood flow in the smallest vessels, enhancing oxygen delivery and waste removal at the tissue level.\n\nPatient-Centric Benefits:\n\nRapid Symptom Relief: Patients often report a noticeable decrease in leg heaviness and pain within the first few weeks of treatment.\nEnhanced Quality of Life: Restores the ability to stand, walk, and engage in daily activities with greater comfort and less discomfort.\nReduced Reliance on Pain Medication: By addressing the underlying inflammation and pain of venous issues and hemorrhoids, it can decrease the need for NSAIDs.\nComplement to Compression Therapy: Works synergistically with compression stockings, often allowing for better tolerance and compliance with compression wear.\nSide Effects and Safety Profile: What to Expect\nFLAVOSHIELD 500 is generally very well-tolerated, with a low incidence of side effects, which are typically mild and transient. This excellent safety profile is a result of its natural origin and high purification.\n\nCommon Side Effects (Rare and usually mild):\n\nGastrointestinal: Some individuals may experience mild, transient digestive disturbances such as nausea, stomach pain, diarrhea, or heartburn. Taking the tablet with a meal can often mitigate this.\nNeurological: Occasional reports of headache or dizziness.\nAllergic Reactions: Very rare cases of skin rash or itching have been reported.\nImportant Safety Considerations:\n\nPregnancy and Lactation: While no teratogenic effects have been demonstrated, as a precaution, use during pregnancy (especially the first trimester) and breastfeeding should only be under the direct supervision of a physician who has weighed the benefits against potential risks.\nDrug Interactions: No significant pharmacokinetic drug interactions have been formally reported. However, as with any medication, it is prudent to inform your doctor about all other medicines and supplements you are taking.\nContraindications: Hypersensitivity to any of the components (Diosmin, Hesperidin, or excipients in the tablet) is a contraindication.\nCrucial Note: FLAVOSHIELD 500 is a treatment for symptoms and a stabilizer of venous function, not a cure for underlying venous valve incompetence. It does not replace definitive interventional treatments (like ablation or surgery) for advanced varicose veins when they are medically indicated. It is essential to receive a proper diagnosis from a healthcare professional to rule out other causes of leg swelling or pain (e.g., cardiac, renal, or hepatic origin).\n\nConclusion: FLAVOSHIELD 500 – A Cornerstone of Comprehensive Venous Care\nIn conclusion, FLAVOSHIELD 500 stands as a robust, scientifically validated agent in the realm of vascular health. Its advanced MPFF technology, combining 450mg of micronized Diosmin with 50mg of Hesperidin, delivers enhanced bioavailability and a powerful, multi-target action that addresses the root causes of venous discomfort: poor tone, capillary fragility, inflammation, and impaired lymphatic drainage.\n\nWhether battling the daily fatigue of heavy legs, managing the acute distress of a hemorrhoidal flare-up, or supporting recovery after a venous procedure, FLAVOSHIELD 500 offers a reliable and well-tolerated therapeutic option. Its benefits in improving symptoms and quality of life are clear, backed by a strong body of clinical evidence.\n\nHowever, optimal venous health is a holistic endeavor. FLAVOSHIELD 500 should be viewed as the pharmacological cornerstone of a broader management plan. This plan should include:\n\nMedical Supervision: Regular consultation with a vascular specialist or phlebologist.\nLifestyle Modifications: Weight management, regular low-impact exercise (walking, swimming), and elevation of the legs.\nCompression Therapy: The use of medically prescribed compression stockings when recommended.\nDietary Awareness: A fiber-rich diet to prevent constipation and straining.\nBy integrating FLAVOSHIELD 500 into this comprehensive approach, individuals can take proactive control of their venous health, shielding their vitality and comfort from the burdens of venous insufficiency. Always consult your healthcare provider to determine if FLAVOSHIELD 500 is appropriate for your specific condition and to establish the correct dosage and treatment duration.\n\nDisclaimer: This content is for informational purposes only and does not constitute medical advice. Always seek the guidance of a qualified healthcare professional with any questions regarding a medical condition or treatment. Do not delay seeking or disregard professional medical advice based on information contained here.", "price": 218.0, "discountamount": 66.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2250, "imageuri": "https://productimages.withfloats.com/actual/6948e7392f14bd83555d1409.png", "tileimageuri": "https://productimages.withfloats.com/tile/6948e7392f14bd83555d1409.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-22T06:37:44.038Z", "updatedon": "2026-02-20T06:30:16.4Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/micronized-purified-flavonoid-fraction/2250", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "FLAVOSHIELD 500", "category": "GENERAL RANGE", "tags": [ "A Deep Dive into Advanced Venous and Vascular Wellness", "human circulatory system", "blood to the heart against gravity.", "Powered by a Micronized Purified Flavonoid Fraction (MPFF)", "Hemorrhoidal Disease", "By reducing blood viscosity and inhibiting red blood cell aggregation", "holistic health strategy.", "Chronic Venous Insufficiency (CVI)", "Varicose Veins", "Hemorrhoids (Piles)", "Venous Ulcers", "Lymphedema", "Post-Surgical Venous Recovery", "micronized purified flavonoid fraction.", "micronized purified flavonoid fraction 500 mg tablet.", "micronized purified flavonoid fraction 1000 mg uses.", "micronized purified flavonoid fraction tablet uses.", "micronized purified flavonoid fraction uses in hindi", "micronized purified flavonoid fraction uses.", "tab micronized purified flavonoid fraction.", "micronized purified flavonoid fraction side effects.", "micronized purified flavonoid fraction 500 mg." ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69400227de5d3e57a9340a50", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Nebivolol and s-amlodipine Tablets 5/2.5 mg", "description": "NEBIVALVE AM is a combination tablet containing Nebivolol and S-Amlodipine, designed to provide effective management of hypertension (high blood pressure). Hypertension is a leading risk factor for cardiovascular diseases in India, including heart attacks, strokes, and kidney complications.\n\nThis dual-action formulation combines the benefits of Nebivolol, a cardio-selective beta-blocker, with S-Amlodipine, a calcium channel blocker, providing comprehensive blood pressure control. The combination helps relax blood vessels, improve blood flow, and reduce cardiac workload, offering a convenient and effective option for patients requiring combination therapy.\n\nUses\n\nNEBIVALVE AM is primarily prescribed for:\n\nEssential Hypertension\nLowers elevated blood pressure to reduce the risk of cardiovascular complications.\n\nCardiovascular Risk Reduction\nHelps in preventing heart attacks, strokes, and heart failure in high-risk patients.\n\nManagement of Stable Angina\nBy reducing cardiac workload and improving oxygen supply to the heart.\n\nCombination Therapy in Resistant Hypertension\nSuitable for patients who do not achieve target blood pressure with single-drug therapy.\n\nBenefits\n1. Dual Mechanism of Action\n\nNebivolol: Blocks beta-1 adrenergic receptors in the heart, reducing heart rate and cardiac output. It also promotes nitric oxide release, helping dilate blood vessels.\n\nS-Amlodipine: Relaxes vascular smooth muscles by blocking calcium channels, improving blood flow and reducing blood pressure.\n\n2. Effective Blood Pressure Control\n\nThe combination provides better blood pressure reduction compared to either drug alone, helping patients achieve their target levels faster.\n\n3. Cardiovascular Protection\n\nReduces strain on the heart, lowers risk of stroke, and supports overall heart health.\n\n4. Once-Daily Convenience\n\nThe tablet can be taken once daily, enhancing patient adherence to therapy.\n\n5. Well-Tolerated Formulation\n\nBoth Nebivolol and S-Amlodipine are generally well tolerated, minimizing side effects when used as prescribed.\n\nDosage\n\nTypical Dose: One tablet of NEBIVALVE AM once daily, preferably at the same time each day.\n\nAdministration: Swallow the tablet whole with water. Do not crush or chew.\n\nIndividualization: The dose may be adjusted by the physician based on blood pressure response and patient tolerability.\n\nLifestyle Measures: Continue dietary modifications, regular exercise, and salt restriction alongside medication for optimal results.\n\nImportant: Do not stop the medication abruptly without consulting your doctor, as sudden withdrawal may worsen blood pressure control or cardiac function.\n\nSide Effects\n\nNEBIVALVE AM is generally well tolerated, but some patients may experience mild side effects, including:\n\nDizziness or lightheadedness\n\nFatigue or weakness\n\nHeadache\n\nFlushing or swelling of ankles (edema)\n\nMild gastrointestinal discomfort\n\nRare but Serious Side Effects\n\nSlow heart rate (bradycardia)\n\nSevere hypotension (low blood pressure)\n\nWorsening of heart failure in susceptible patients\n\nAllergic reactions such as rash or swelling\n\nSeek immediate medical attention if severe symptoms such as fainting, chest pain, or shortness of breath occur.\n\nPrecautions and Warnings\n\nPregnancy and Breastfeeding: Use only if clearly indicated and prescribed by a doctor.\n\nHeart Conditions: Inform your doctor if you have heart failure, arrhythmia, or a recent heart attack.\n\nKidney or Liver Impairment: Dose adjustment may be necessary.\n\nDiabetes: Nebivolol may mask symptoms of low blood sugar; monitor blood glucose closely.\n\nDrug Interactions: Notify your doctor about all medications, especially other blood pressure drugs, anti-arrhythmics, or diuretics.\n\nAvoid Alcohol: Alcohol may increase the risk of hypotension or dizziness.\n\nRegular Monitoring: Blood pressure and heart rate should be monitored periodically during therapy.\n\nConclusion\n\nNEBIVALVE AM (Nebivolol and S-Amlodipine Tablets) is a safe and effective combination therapy for managing hypertension and reducing cardiovascular risks. By combining Nebivolol’s beta-blocking and vasodilatory effects with S-Amlodipine’s calcium channel blocking action, it provides superior blood pressure control and cardiovascular protection.", "price": 210.0, "discountamount": 63.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2246, "imageuri": "https://productimages.withfloats.com/actual/69400229d51eeda87e74dba0.png", "tileimageuri": "https://productimages.withfloats.com/tile/69400229d51eeda87e74dba0.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-15T12:42:15.327Z", "updatedon": "2026-01-08T06:58:17.841Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/nebivolol-and-s-amlodipine-tablets-5-2-5-mg/2246", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "NEBIVALVE AM", "category": "CARDIOLOGY", "tags": [ "nebivolol and s-amlodipine tablets", "nebivolol and s-amlodipine tablets uses", "nebivolol and s-amlodipine tablets uses in hindi", "nebivolol", "s-amlodipine tablets", "hypertension (high blood pressure)", "heart attacks", "strokes", "kidney complications", "blood pressure contro", "helps relax blood vessels", "improve blood flow", "Hypertension is a leading risk factor for cardiovascular diseases in India", "nebivolol and s amlodipine tablets", "nebivolol s amlodipine combination tablet", "nebivolol with s amlodipine tablets", "nebivolol + s amlodipine medicine", "nebivolol s amlodipine tablet uses", "nebivolol and s amlodipine tablets uses in hypertension", "nebivolol and s amlodipine tablets composition", "nebivolol and s amlodipine tablets dosage", "nebivolol and s amlodipine tablets benefits", "nebivolol and s amlodipine tablets for high blood pressure", "nebivolol and s amlodipine tablets how it works" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "693c0c9c0c30ac5c9f8203b4", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Isosorbide Mononitrate IP 30mg Tablets", "description": "CARDULES ISMN SR 30 tablets provide sustained-release Isosorbide Mononitrate IP 30mg, a nitrate medication designed for long-term management of angina in patients with coronary artery disease. This formulation from Steris Healthcare Pvt Ltd ensures steady vasodilation to improve heart blood flow and reduce chest pain episodes. It supports daily activities by minimizing oxygen demand on the heart muscle.​\nProduct Overview\nCARDULES ISMN SR 30 contains Isosorbide Mononitrate IP 30mg in a sustained-release matrix, allowing once-daily dosing for consistent therapeutic levels over 12-24 hours. The tablet's extended-release technology prevents peak-trough fluctuations common in immediate-release forms, promoting better patient compliance. Each film-coated tablet delivers precise bioavailability, with the active metabolite nitric oxide activating guanylate cyclase to boost cyclic GMP, relaxing vascular smooth muscle primarily in veins.​\n\nThis mechanism reduces preload (venous return to the heart) and afterload (arterial resistance), easing cardiac workload without significantly affecting heart rate. Unlike short-acting nitrates for acute relief, CARDULES ISMN SR 30 targets prophylaxis in chronic stable angina, often prescribed alongside beta-blockers or calcium channel blockers. Available in strips of 10 tablets, it undergoes rigorous quality testing at Steris facilities to meet IP standards, ensuring purity and stability.​\n\nKey Uses\nCARDULES ISMN SR 30 primarily prevents angina pectoris in coronary artery disease, where narrowed vessels limit oxygen supply during exertion. Patients experience fewer chest pain attacks during walking, climbing stairs, or stress.​\n\nIt manages chronic stable angina by enhancing myocardial perfusion, suitable for long-term therapy in adults over 18. Healthcare providers may use it adjunctively for coronary spasm or post-myocardial infarction prophylaxis to stabilize symptoms.​\n\nIn select cases, it aids heart failure management by offloading the heart, though not as monotherapy. Always initiate under cardiology supervision with dose titration to tolerance.​\n\nMajor Benefits\nThe sustained-release profile offers 24-hour protection with single morning dosing, improving adherence and lifestyle quality for active patients. It boosts exercise tolerance by 20-30% in trials, allowing longer physical efforts without angina onset.​\n\nBy dilating vessels, it decreases ischemia risk, potentially lowering hospitalization rates for acute episodes. Compared to placebo, users report halved attack frequency within weeks, enhancing daily productivity and emotional well-being.​\n\nBenefit\tMechanism\tPatient Outcome\nAngina Prevention\tVasodilation reduces preload/afterload ​\tFewer attacks, better exertion capacity\nSteady Relief\tSR formulation maintains levels ​\tOnce-daily convenience, no fluctuations\nHeart Protection\tImproves O2 delivery ​\tReduced ischemia, enhanced QoL\nCompliance Boost\tSimple regimen ​\tHigher adherence vs multiple doses\nAdditional perks include minimal impact on blood pressure in normotensives and compatibility with anti-anginals, making it versatile in combo therapy.\n\nPotential Side Effects\nCommon effects include headache (dose-related, often transient in first week), dizziness, or flushing due to vasodilation—hydrate and rise slowly to manage. Gastrointestinal upset like nausea occurs in 5-10% initially.​\n\nOrthostatic hypotension risks fainting, especially early; avoid alcohol or other vasodilators. Rare serious issues encompass severe hypotension, tachycardia, or methemoglobinemia with overdose—monitor blood pressure regularly.​\n\nAllergic reactions (rash, itching) or vision changes warrant discontinuation. Contraindicated in hypotension, glaucoma, or recent PDE5 inhibitor use; caution in anemia or hypothyroidism.​\n\nDosage Guidelines\nStart with 30mg once daily upon waking, swallowed whole without crushing. Titrate to 60mg if tolerated after 3-7 days, max 120mg/day. Take on empty stomach for optimal absorption; avoid late dosing to prevent nocturnal headaches.​\n\nAdjust for elderly or renal/hepatic impairment. Tolerance may develop—nitrate-free interval (evening) helps sustain efficacy. Store below 30°C.​\nConclusion\nCARDULES ISMN SR 30 empowers angina patients with reliable, once-daily prevention, restoring confidence in routine activities under Steris Healthcare's quality assurance. Its targeted vasodilation balances efficacy and tolerability for sustained heart health", "price": 65.0, "discountamount": 19.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2243, "imageuri": "https://productimages.withfloats.com/actual/693c0ca6391a3fa44b0608d8.png", "tileimageuri": "https://productimages.withfloats.com/tile/693c0ca6391a3fa44b0608d8.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-12T12:37:48.92Z", "updatedon": "2025-12-12T12:37:48.92Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/isosorbide-mononitrate-ip-30mg-tablets/2243", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CARDULES ISMN SR 30", "category": "", "tags": [ "Isosorbide Mononitrate IP 30mg Tablets", "coronary artery disease", "heart blood flow and reduce chest pain episodes", "oxygen demand on the heart muscle", "relaxing vascular smooth muscle primarily in veins" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69142bf71d499513a92e5772", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Nicorandil Tablets 5mg", "description": "Nicorandil Tablets 5 mg is a vasodilatory anti-anginal medication widely prescribed for the management and prevention of angina pectoris (chest pain) associated with coronary artery disease (CAD). Angina results from an imbalance between the heart’s oxygen demand and supply due to restricted blood flow in the coronary arteries. Nicorandil offers a dual mechanism of action — acting both as a nitrate-like vasodilator and a potassium channel opener, making it unique among anti-anginal agents.\n\nBy improving oxygen delivery to the myocardium and reducing cardiac workload, Nicorandil 5 mg Tablets provide effective relief from anginal pain and reduce the frequency and severity of ischemic episodes. It is also beneficial in preventing future attacks, improving exercise tolerance, and enhancing the overall quality of life in patients with chronic stable angina.\n\nComposition\n\nEach tablet contains:\n\nNicorandil IP – 5 mg\n\nExcipients – q.s.\n\nNicorandil tablets are available in film-coated form to ensure stability, easy swallowing, and optimal absorption. They are manufactured in compliance with Good Manufacturing Practices (GMP) standards to ensure safety, purity, and efficacy.\n\nPharmacological Action / Mechanism of Action\n\nNicorandil exhibits a dual mechanism that makes it distinct among anti-anginal drugs:\n\nNitrate-Like Effect:\nNicorandil acts as a nitric oxide (NO) donor. Nitric oxide activates guanylate cyclase, increasing cyclic GMP (cGMP) levels in vascular smooth muscle. This leads to relaxation of blood vessels, particularly veins and large arteries, thereby reducing preload and afterload on the heart. This nitrate-like activity lowers myocardial oxygen demand.\n\nPotassium Channel Opening Effect:\nNicorandil opens ATP-sensitive potassium (KATP) channels in vascular smooth muscle, resulting in arteriolar vasodilation. This increases coronary blood flow and improves oxygen supply to ischemic heart tissues.\n\nTogether, these effects reduce cardiac workload, enhance coronary perfusion, and prevent anginal pain by correcting the oxygen supply-demand mismatch in the heart muscle.\n\nUses and Indications\n\nNicorandil Tablets 5 mg are indicated for the treatment and prevention of angina pectoris in adults, particularly:\n\nChronic Stable Angina:\n\nHelps reduce the frequency and severity of chest pain associated with exertion or emotional stress.\n\nProphylaxis of Angina Attacks:\n\nUsed regularly to prevent anginal episodes, especially in patients with known coronary artery disease.\n\nAdjunct Therapy in Ischemic Heart Disease (IHD):\n\nCan be used alongside beta-blockers, calcium channel blockers, or antiplatelet drugs for enhanced symptom control and long-term protection.\n\nImprovement of Exercise Tolerance:\n\nReduces the likelihood of anginal pain during physical activity, enabling patients to perform daily tasks comfortably.\n\nIn some clinical cases, Nicorandil is also considered for post-myocardial infarction recovery, as it improves coronary perfusion, although this is at the discretion of a cardiologist.\n\nDosage and Administration\n\nRecommended Starting Dose: 5 mg to 10 mg twice daily.\n\nMaintenance Dose: May be increased gradually to 10–20 mg twice daily, depending on clinical response and tolerance.\n\nThe tablets should be swallowed whole with water, preferably at the same times each day.\n\nNicorandil should not be stopped abruptly; dosage tapering is recommended to avoid rebound angina.\n\nAlways follow the dosage instructions provided by the physician.\n\nKey Benefits\n\nDual Mechanism for Comprehensive Relief:\nCombines nitrate-like and potassium channel-opening properties for both arterial and venous dilation, providing superior protection against anginal attacks.\n\nImproves Coronary Blood Flow:\nDilates coronary arteries, increasing oxygen delivery to ischemic myocardial tissues.\n\nReduces Cardiac Workload:\nBy decreasing preload (venous return) and afterload (arterial resistance), Nicorandil minimizes the heart’s oxygen consumption.\n\nRapid Onset of Action:\nNicorandil acts within a short duration, offering quick relief from anginal discomfort.\n\nPrevents Future Angina Episodes:\nRegular use helps maintain steady control of chest pain, improving exercise capacity and quality of life.\n\nCompatible with Other Cardiac Medications:\nCan be safely used alongside antiplatelet agents, beta-blockers, ACE inhibitors, and statins as part of comprehensive cardiac care.\n\nFavorable Safety Profile:\nCompared to nitrates, Nicorandil carries a lower risk of tolerance development, making it suitable for long-term therapy.\n\nEnhances Myocardial Protection:\nNicorandil’s KATP channel activation provides additional cardioprotective effects by improving microvascular blood flow and limiting ischemic damage during stress.\n\nPrecautions and Warnings\n\nAlthough Nicorandil is generally well-tolerated, certain precautions are advised:\n\nHypotension:\nNicorandil may cause a drop in blood pressure due to vasodilation. Caution is advised in patients with hypotension or dehydration.\n\nConcurrent Use with Nitrates:\nShould not be used together with other nitrate medications to avoid severe hypotension.\n\nOral or Gastrointestinal Ulcers:\nRarely, Nicorandil may cause ulcerations in the mouth, intestines, or skin. Treatment should be discontinued if ulceration occurs.\n\nPatients with Low Blood Volume:\nUse cautiously in individuals with hypovolemia or those on diuretics.\n\nDriving and Machinery:\nDizziness or light-headedness may occur; avoid driving until effects are known.\n\nPregnancy and Lactation:\nShould be used only if prescribed by a physician when the potential benefits outweigh the risks.\n\nPossible Side Effects\n\nNicorandil is generally safe but may cause some side effects, particularly at the start of therapy or with higher doses. Common and rare adverse reactions include:\n\nCommon Side Effects:\n\nHeadache (due to vasodilation)\n\nFlushing or warmth sensation\n\nDizziness or light-headedness\n\nNausea or mild stomach upset\n\nFatigue or weakness\n\nLess Common / Rare Side Effects:\n\nHypotension (low blood pressure)\n\nPalpitations or tachycardia\n\nMouth ulcers, anal ulcers, or skin ulceration (uncommon but serious — discontinue if occurs)\n\nRash or allergic reaction\n\nVisual disturbances (rare and usually reversible)\n\nIf any severe reaction or persistent discomfort occurs, medical attention should be sought promptly.\n\nDrug Interactions\n\nAvoid concomitant use with nitrates or phosphodiesterase type-5 inhibitors (e.g., Sildenafil, Tadalafil), as it may cause a dangerous fall in blood pressure.\n\nCaution with antihypertensive drugs or diuretics, which may enhance hypotensive effects.\n\nAlcohol consumption can potentiate dizziness or hypotension and should be limited.\n\nStorage and Handling\n\nStore below 30°C, protected from moisture and direct sunlight.\n\nKeep out of reach of children.\n\nDo not use tablets past the expiry date or if the packaging is damaged.\n\nConclusion\n\nNicorandil Tablets 5 mg offer a modern and effective approach to managing angina pectoris, providing reliable relief through their dual-action mechanism. By combining nitrate-like vasodilation with potassium channel opening, Nicorandil ensures both oxygen supply improvement and reduction of cardiac workload — the cornerstone of angina management.\n\nIt is well-tolerated, fast-acting, and suitable for long-term therapy, making it a preferred choice for patients with chronic stable angina. Regular use under medical supervision helps reduce the frequency of chest pain, improve physical endurance, and enhance the overall quality of life in individuals with coronary artery disease.", "price": 381.0, "discountamount": 115.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2202, "imageuri": "https://productimages.withfloats.com/actual/69142c03b53db80943abd33d.png", "tileimageuri": "https://productimages.withfloats.com/tile/69142c03b53db80943abd33d.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-12T06:40:55.795Z", "updatedon": "2026-01-12T07:51:06.847Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/nicorandil-tablets-5mg/2202", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MAYORANDIL 5 ", "category": "CARDIOLOGYRANGE", "tags": [ "nicorandil tablets 5mg", "nicorandil 5 mg tablets uses", "nicorandil tablet 5mg benefits", "nicorandil 5mg medicine", "nicorandil tablets ip 5 mg", "what is nicorandil 5mg used for", "how does nicorandil tablet work", "nicorandil 5mg mechanism of action", "nicorandil tablets for angina treatment", "nicorandil tablet uses in heart disease", "nicorandil 5mg tablet price in india", "buy nicorandil 5mg tablets online", "nicorandil 5mg tablet brands", "nicorandil tablets manufacturer", "nicorandil tablets wholesale supplier" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "68e63e06f3481c1f16d3ae51", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Tenofovir Alafenamide 25 mg", "description": "TELAVINCE AF 25 is primarily indicated for:\n\nHypertension (High Blood Pressure): Effectively helps in lowering elevated blood pressure.\n\nCardiovascular Risk Reduction: Supports heart health and reduces the risk of heart attack, stroke, and other complications related to high blood pressure.\n\nPatients requiring combination therapy: Ideal for individuals who need more than one antihypertensive agent for optimal blood pressure control.\n\nMechanism of Action:\n\nTELAVINCE AF 25 combines two mechanisms for effective blood pressure management:\n\nTelmisartan: Blocks angiotensin II receptors, preventing blood vessel constriction and thereby reducing blood pressure.\n\n[AF Component, e.g., Amlodipine]: Relaxes blood vessels by inhibiting calcium entry into vascular smooth muscles, improving blood flow and reducing strain on the heart.\n\nThis dual-action combination provides better efficacy than single-drug therapy while maintaining a favorable safety profile.\n\nDosage and Administration:\n\nRecommended Dose: As prescribed by a healthcare professional, typically one tablet daily.\n\nRoute: Oral, with water.\n\nTiming: Can be taken with or without food, preferably at the same time each day.\n\nAdjustment: Dose may be adjusted based on individual response and tolerability.\n\nImportant: Always follow your doctor’s instructions. Do not change the dose or stop medication without medical advice.\n\nKey Benefits of TELAVINCE AF 25:\n\nEffective blood pressure control with dual-action therapy.\n\nReduces the risk of cardiovascular complications associated with hypertension.\n\nConvenient once-daily dosing for better patient adherence.\n\nWell-tolerated with minimal side effects.\n\nSuitable for long-term use under medical supervision.\n\nSafety and Precautions:\n\nInform your doctor if you have kidney disease, liver disease, or heart failure.\n\nPregnant or breastfeeding women should use only if recommended by a physician.\n\nAvoid excessive use of potassium-containing salt substitutes.\n\nRegular monitoring of blood pressure and kidney function is recommended.\n\nDo not combine with other angiotensin receptor blockers (ARBs) unless prescribed.\n\nPossible Side Effects:\n\nWhile generally well-tolerated, some patients may experience:\n\nDizziness or lightheadedness\n\nFatigue or weakness\n\nMild swelling of ankles or feet\n\nNausea or headache\n\nSeek immediate medical attention if you experience:\n\nSevere allergic reactions\n\nSwelling of face, lips, or throat\n\nDifficulty breathing\n\nStorage Instructions:\n\nStore in a cool, dry place away from sunlight.\n\nKeep out of reach of children and pets.\n\nDo not use after the expiry date mentioned on the package.\n\nWhy Choose TELAVINCE AF 25:\n\nDeveloped by Steris Healthcare Pvt. Ltd, a trusted pharmaceutical company.\n\nEnsures quality, safety, and efficacy in every tablet.\n\nDesigned for patient convenience with once-daily dosing.\n\nBacked by clinical research for effective hypertension management.\n\nDisclaimer:\n\nThe information provided here is for educational purposes only. TELAVINCE AF 25 should be used only under medical supervision. Consult your healthcare provider for personalized advice. Side effects may vary from person to person.\n\n", "price": 1566.0, "discountamount": 470.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2184, "imageuri": "https://productimages.withfloats.com/actual/68fccd73d1374009faa1f8c9.png", "tileimageuri": "https://productimages.withfloats.com/tile/68fccd73d1374009faa1f8c9.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-10-08T10:33:42.289Z", "updatedon": "2026-01-12T08:19:13.781Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/tenofovir-alafenamide-25-mg/2184", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "TELAVINCE AF25", "category": "GENERAL RANGE", "tags": [ "tenofovir alafenamide 25 mg uses in hindi", "what is tenofovir alafenamide 25 mg tablet used for", "tenofovir alafenamide 25 mg for hepatitis b treatment", "tenofovir alafenamide 25 mg mechanism of action", "tenofovir alafenamide 25 mg how it works", "tenofovir alafenamide 25 mg benefits and risks", "tenofovir alafenamide 25 mg tablet information", "tenofovir alafenamide 25 mg dosage guide", "tenofovir alafenamide 25 mg medicine details", "what is tenofovir alafenamide 25 mg used for", "is tenofovir alafenamide 25 mg safe", "is tenofovir alafenamide 25 mg safe", "does tenofovir alafenamide 25 mg damage kidneys" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "68e63c17e7475f0f453d4b6e", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "tenofovir emtricitabine efavirenz", "description": "TELAVINCE EM is primarily indicated for the management of:\n\nHypertension (High Blood Pressure): Helps in reducing elevated blood pressure effectively.\n\nCardiovascular Risk Reduction: Supports heart health and reduces the risk of stroke, heart attack, and related complications.\n\nPatients requiring combination therapy: Suitable for individuals who need more than one antihypertensive for better blood pressure control.\n\nMechanism of Action:\n\nTELAVINCE EM works through a dual mechanism to control blood pressure:\n\nTelmisartan: Blocks angiotensin II receptors, preventing blood vessel constriction and reducing blood pressure.\n\n[EM Component, e.g., Amlodipine]: Relaxes blood vessels by inhibiting calcium entry into vascular smooth muscles, improving blood flow and reducing strain on the heart.\n\nThe combination ensures better efficacy than monotherapy while maintaining a favorable safety profile.\n\nDosage and Administration:\n\nRecommended Dose: As prescribed by a healthcare professional, typically one tablet daily.\n\nRoute: Oral administration with water.\n\nTiming: Can be taken with or without food, preferably at the same time each day.\n\nAdjustment: Dose may be modified based on individual response and tolerability.\n\nImportant: Always follow your doctor’s instructions. Do not alter the dose or stop medication without medical advice.\n\nKey Benefits of TELAVINCE EM:\n\nEffective blood pressure control with dual-action therapy.\n\nReduces risk of cardiovascular events associated with hypertension.\n\nConvenient once-daily dosing improves patient compliance.\n\nWell-tolerated with a low incidence of side effects.\n\nSuitable for long-term use under medical supervision.\n\nSafety and Precautions:\n\nInform your doctor if you have kidney disease, liver disease, or heart failure.\n\nPregnant or breastfeeding women should avoid use unless advised by a physician.\n\nAvoid excessive salt substitutes containing potassium.\n\nRegular blood pressure and kidney function monitoring is recommended.\n\nDo not use in combination with other angiotensin receptor blockers (ARBs) unless prescribed.\n\nPossible Side Effects:\n\nAlthough TELAVINCE EM is generally well-tolerated, some patients may experience:\n\nDizziness or lightheadedness\n\nFatigue or weakness\n\nMild swelling in ankles or feet\n\nNausea or headache\n\nSeek immediate medical attention if you experience severe side effects such as difficulty breathing, swelling of face or throat, or severe allergic reactions.\n\nStorage Instructions:\n\nStore in a cool, dry place away from direct sunlight.\n\nKeep out of reach of children and pets.\n\nDo not use after the expiry date mentioned on the package.\n\nWhy Choose TELAVINCE EM:\n\nDeveloped by Steris Healthcare Pvt. Ltd, a trusted name in pharmaceutical excellence.\n\nEnsures quality, safety, and efficacy in every tablet.\n\nDesigned for optimal patient compliance with convenient dosing.\n\nBacked by clinical research for managing hypertension effectively.\n\nDisclaimer:\n\nThe information provided here is intended for educational purposes only. TELAVINCE EM should be used only under medical supervision. Consult your healthcare provider for personalized advice. Side effects may vary from person to person.", "price": 4715.0, "discountamount": 1415.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2183, "imageuri": "https://productimages.withfloats.com/actual/68fcce7d2c390674e0a52e8e.png", "tileimageuri": "https://productimages.withfloats.com/tile/68fcce7d2c390674e0a52e8e.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-10-08T10:25:27.075Z", "updatedon": "2026-01-09T06:53:36.178Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/tenofovir-emtricitabine-efavirenz/2183", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "TELAVINCE EM", "category": "GENERAL RANGE", "tags": [ "tenofovir emtricitabine efavirenz uses in hiv treatment", "how tenofovir emtricitabine efavirenz works", "tenofovir emtricitabine efavirenz combination explained", "what is tenofovir emtricitabine efavirenz tablet", "tenofovir emtricitabine efavirenz medicine details", "tenofovir emtricitabine efavirenz for hiv patients", "tenofovir emtricitabine efavirenz antiviral medicine", "tenofovir emtricitabine efavirenz drug information", "tenofovir emtricitabine efavirenz for hiv 1 infection", "hiv treatment with tenofovir emtricitabine efavirenz", "tenofovir emtricitabine efavirenz side effects", "tenofovir emtricitabine efavirenz long term effects", "is tenofovir emtricitabine efavirenz safe", "tenofovir emtricitabine efavirenz tablets ip", "what is tenofovir emtricitabine efavirenz used for", "who should take tenofovir emtricitabine efavirenz" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false } ], "hasmoreitems": false, "isapirequest": false, "totalresults": 27, "query": null, "floatingpoint": null }