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{ "products": [ { "_id": "6a26bc218e598f29a23bee80", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "indomethacin and paracetamol capsules", "description": "Indomethacin and Paracetamol Capsules: Complete Guide to Uses, Benefits, Composition, and Safety\nWhat Are Indomethacin and Paracetamol Capsules?\n\nIndomethacin and Paracetamol Capsules are a combination medication used to relieve pain, reduce inflammation, and control fever associated with various acute and chronic conditions. This combination brings together the powerful anti-inflammatory action of Indomethacin and the well-established pain-relieving and fever-reducing properties of Paracetamol, making it an effective treatment option for patients experiencing musculoskeletal pain, arthritis-related discomfort, headaches, post-operative pain, and fever.\n\nThe dual-action formula is designed to provide faster and more comprehensive symptom relief compared to single-ingredient therapies. Healthcare professionals often prescribe this combination when pain and inflammation occur together and require effective management.\n\nComposition of Indomethacin and Paracetamol Capsules\n\nThe formulation contains the following active pharmaceutical ingredients:\n\nIndomethacin\n\nA potent non-steroidal anti-inflammatory drug (NSAID) that helps reduce inflammation, swelling, stiffness, and pain.\n\nParacetamol (Acetaminophen)\n\nAn analgesic and antipyretic agent used to relieve pain and reduce fever.\n\nTogether, these ingredients provide a balanced approach to managing pain, inflammation, and elevated body temperature.\n\nHow Do Indomethacin and Paracetamol Capsules Work?\n\nIndomethacin and Paracetamol Capsules work through complementary mechanisms to deliver effective relief from painful and inflammatory conditions.\n\nIndomethacin Action\n\nIndomethacin inhibits cyclooxygenase (COX) enzymes responsible for producing prostaglandins, which are chemicals that contribute to inflammation, pain, and swelling. By reducing prostaglandin production, Indomethacin helps alleviate discomfort and improve mobility.\n\nParacetamol Action\n\nParacetamol acts primarily within the central nervous system to block pain signals and regulate body temperature. It effectively reduces fever and enhances overall pain control.\n\nThe combination provides broader symptom relief by addressing both peripheral inflammation and central pain perception.\n\nComposition Benefits of Indomethacin and Paracetamol Capsules\n\nThe combination offers multiple therapeutic benefits:\n\nEffective pain management\nStrong anti-inflammatory action\nFever reduction\nImproved mobility and comfort\nFaster symptom relief\nBetter patient compliance through combination therapy\nMechanism of Each Ingredient\nIndomethacin\nMechanism of Action\n\nIndomethacin belongs to the NSAID class and works by inhibiting cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes. These enzymes are involved in the production of prostaglandins that cause inflammation and pain.\n\nTherapeutic Effects\nReduces inflammation\nRelieves joint pain\nMinimizes swelling\nImproves flexibility and movement\nControls pain associated with arthritis and musculoskeletal disorders\nParacetamol\nMechanism of Action\n\nParacetamol acts centrally by inhibiting pain-mediating pathways in the brain and affecting the hypothalamic heat-regulating center.\n\nTherapeutic Effects\nReduces fever\nRelieves mild to moderate pain\nImproves patient comfort\nEnhances overall pain management when combined with NSAIDs\nKey Benefits of Indomethacin and Paracetamol Capsules\nPowerful Pain Relief\n\nThe combination effectively manages moderate to severe pain caused by inflammatory and non-inflammatory conditions.\n\nDual Action Formula\n\nProvides both anti-inflammatory and analgesic effects for comprehensive symptom control.\n\nEffective Fever Reduction\n\nParacetamol helps lower elevated body temperature associated with infections and inflammatory diseases.\n\nImproved Joint Mobility\n\nIndomethacin reduces stiffness and swelling, making movement easier and more comfortable.\n\nFaster Recovery Support\n\nBy controlling pain and inflammation, the capsules help patients return to normal daily activities sooner.\n\nConvenient Combination Therapy\n\nCombines two trusted therapeutic agents into a single dosage form for improved treatment adherence.\n\nUses of Indomethacin and Paracetamol Capsules\n\nHealthcare professionals may prescribe Indomethacin and Paracetamol Capsules for various conditions, including:\n\nOsteoarthritis\n\nHelps relieve:\n\nJoint pain\nSwelling\nStiffness\nReduced mobility\nRheumatoid Arthritis\n\nProvides symptomatic relief from chronic inflammation and discomfort.\n\nAnkylosing Spondylitis\n\nHelps reduce spinal pain and stiffness associated with inflammatory conditions.\n\nAcute Musculoskeletal Pain\n\nUseful for:\n\nMuscle injuries\nLigament strains\nSports injuries\nBack pain\nGouty Arthritis\n\nIndomethacin is particularly effective in managing acute gout attacks and associated inflammation.\n\nDental Pain\n\nProvides relief from pain and swelling following dental procedures or infections.\n\nPost-Operative Pain\n\nSupports pain management after surgical interventions.\n\nFever Associated with Painful Conditions\n\nParacetamol helps control elevated body temperature while Indomethacin addresses inflammation.\n\nHeadache and Migraine\n\nMay be used under medical supervision for inflammatory headaches and migraine-related discomfort.\n\nWhy Choose Indomethacin and Paracetamol Capsules?\nComprehensive Symptom Relief\n\nThe combination targets pain, inflammation, and fever simultaneously.\n\nTrusted Active Ingredients\n\nBoth Indomethacin and Paracetamol have long-established clinical use in pain management.\n\nEnhanced Pain Control\n\nCombining two different mechanisms of action often provides superior relief compared to monotherapy.\n\nEffective for Inflammatory Conditions\n\nParticularly beneficial in arthritis, gout, and musculoskeletal disorders.\n\nImproved Patient Convenience\n\nA single capsule provides multiple therapeutic benefits, reducing the need for separate medications.\n\nSuitable for Short-Term Pain Management\n\nOften prescribed for acute painful conditions requiring rapid symptom control.\n\nImportant Safety Information\n\nBefore using Indomethacin and Paracetamol Capsules, consider the following precautions:\n\nUse Only as Prescribed\n\nTake the medication exactly as directed by your healthcare professional.\n\nAvoid Exceeding Recommended Dosage\n\nOveruse may increase the risk of serious side effects, including liver damage and gastrointestinal complications.\n\nGastrointestinal Precautions\n\nIndomethacin may cause:\n\nStomach irritation\nGastric ulcers\nGastrointestinal bleeding\n\nPatients with a history of ulcers should consult their physician before use.\n\nLiver Disease Warning\n\nParacetamol should be used cautiously in patients with liver impairment.\n\nKidney Function Monitoring\n\nPatients with kidney disease may require dose adjustments and regular monitoring.\n\nCardiovascular Considerations\n\nNSAIDs may increase cardiovascular risks in certain patients.\n\nPregnancy and Breastfeeding\n\nUse only if specifically recommended by a healthcare provider after evaluating the benefits and risks.\n\nAlcohol Consumption\n\nAvoid alcohol while taking this medication as it may increase the risk of liver and stomach-related side effects.\n\nDrug Interactions\n\nInform your healthcare provider if you are taking:\n\nBlood thinners\nOther NSAIDs\nCorticosteroids\nAntihypertensive medicines\nDiuretics\nAntidiabetic medications\nPossible Side Effects\n\nLike all medications, Indomethacin and Paracetamol Capsules may cause side effects in some individuals.\n\nCommon side effects include:\n\nNausea\nVomiting\nIndigestion\nStomach pain\nHeadache\nDizziness\nDrowsiness\nHeartburn\n\nSeek immediate medical attention if you experience:\n\nSevere allergic reactions\nDifficulty breathing\nBlack or bloody stools\nSevere abdominal pain\nYellowing of the skin or eyes\nUnusual bleeding\nStorage Instructions\nStore in a cool, dry place.\nProtect from moisture and direct sunlight.\nKeep the capsules in their original packaging.\nKeep out of reach of children.\nDo not use after the expiry date mentioned on the package.\nConclusion\n\nIndomethacin and Paracetamol Capsules are an effective combination therapy for managing pain, inflammation, and fever associated with a wide range of medical conditions. The anti-inflammatory power of Indomethacin combined with the analgesic and antipyretic effects of Paracetamol provides comprehensive symptom relief and improved patient comfort.", "price": 65.0, "discountamount": 19.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2450, "imageuri": "https://productimages.withfloats.com/actual/6a26bc233932ef9eb0a842e7.png", "tileimageuri": "https://productimages.withfloats.com/tile/6a26bc233932ef9eb0a842e7.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-06-08T12:57:05.96Z", "updatedon": "2026-06-08T12:57:05.96Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/indomethacin-and-paracetamol-capsules/2450", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "INDOMATHS P 25/325 CAPSULES", "category": "ORTHOLOGYRANG", "tags": [ "indomethacin and paracetamol capsules" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6a03166b3678f86a626aca60", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "glycopyrrolate formoterol fumarate and budesonide inhalation", "description": "Glycopyrrolate Formoterol Fumarate and Budesonide Inhalation\nWhen patients and healthcare providers search for a reliable inhalation therapy for chronic respiratory conditions, Glycopyrrolate + Formoterol Fumarate + Budesonide inhalation stands out as a modern triple-combination treatment designed to support long-term breathing management. This combination is commonly prescribed in patients requiring advanced maintenance therapy for chronic airway obstruction and inflammation.\nThe three active ingredients work together to help open the airways, reduce inflammation, and improve overall lung function. Triple-combination inhalation therapy is widely used in chronic respiratory management and is commonly prescribed for adults needing long-term control of airway symptoms. \nWhat is Glycopyrrolate Formoterol Fumarate and Budesonide Inhalation?\nThis inhalation contains three clinically proven medicines:\n1. Glycopyrrolate\nGlycopyrrolate helps relax airway muscles by blocking muscarinic receptors. This action keeps air passages open for easier breathing.\n2. Formoterol Fumarate\nFormoterol is a long-acting bronchodilator that helps maintain airway relaxation for extended periods.\n3. Budesonide\nBudesonide reduces airway inflammation, swelling, and irritation, helping lower flare-ups in chronic respiratory disease.\nTogether, these three medicines create a comprehensive treatment option for respiratory maintenance therapy. \nKey Buyer Benefits of This Inhalation\nHealthcare professionals and procurement teams often choose this inhalation because of its multiple benefits:\nSuperior Triple Action\nInstead of prescribing multiple inhalers, this triple combination provides three therapeutic actions in one inhalation device.\nImproved Lung Function\nPatients may experience better airflow and improved breathing comfort with regular prescribed use.\nReduced Respiratory Flare-Ups\nClinical use shows that triple therapy can help reduce worsening episodes in chronic airway disease. \nBetter Patient Compliance\nA single inhaler may improve convenience and adherence to treatment plans.\nCommon Uses of Glycopyrrolate Formoterol Fumarate and Budesonide Inhalation\nThis inhalation is commonly prescribed for:\n\n\nChronic Obstructive Pulmonary Disease (COPD)\n\n\nChronic bronchitis\n\n\nAirflow limitation disorders\n\n\nLong-term respiratory maintenance therapy\n\n\nPhysician-directed asthma maintenance in appropriate patients\n\n\nThis medicine is for maintenance treatment and is not intended for immediate relief of sudden breathing attacks. \nHow Does This Triple Combination Work?\nEach component contributes differently:\nGlycopyrrolate reduces airway tightening.\nFormoterol Fumarate keeps air passages open for longer periods.\nBudesonide controls airway inflammation.\nThis combined mechanism helps support easier breathing and better respiratory stability.\nWhy Buyers Choose This Product\nHospitals, distributors, pharmacies, and healthcare procurement teams often look for products that offer:\n\n\nHigh therapeutic value\n\n\nReliable respiratory support\n\n\nEasy inhalation administration\n\n\nReduced need for multiple inhalers\n\n\nStrong physician acceptance\n\n\nBecause this product combines anti-inflammatory and bronchodilator benefits, it remains a preferred respiratory care option.\nDosage and Administration\nThe exact dosage should always be prescribed by a healthcare professional.\nTypical maintenance inhalation regimens are taken twice daily depending on formulation and clinical need. Patients should rinse their mouth after use to help reduce local side effects. \nImportant Usage Tips\n\n\nShake inhaler before use\n\n\nUse exactly as prescribed\n\n\nDo not exceed recommended doses\n\n\nPrime inhaler if instructed\n\n\nStore in a cool and dry place\n\n\nPossible Side Effects\nLike all prescription medicines, some users may experience side effects such as:\n\n\nDry mouth\n\n\nThroat irritation\n\n\nHoarseness\n\n\nMild cough\n\n\nHeadache\n\n\nOral fungal infection\n\n\nFast heartbeat in some patients\n\n\nMost effects are manageable under medical supervision. \nSafety Precautions\nBefore using this inhalation, patients should inform their doctor if they have:\n\n\nHeart disease\n\n\nHigh blood pressure\n\n\nDiabetes\n\n\nThyroid disorders\n\n\nKidney problems\n\n\nLiver disease\n\n\nGlaucoma\n\n\nPregnant or breastfeeding patients should use it only under medical supervision.\nPackaging and Commercial Availability\nThis product is generally available in metered-dose inhaler packaging suitable for:\n\n\nHospitals\n\n\nMedical distributors\n\n\nExport buyers\n\n\nRetail pharmacies\n\n\nRespiratory specialty clinics\n\n\nBulk procurement options may be available depending on manufacturer and supply chain requirements.\nWhy This Inhalation is a Smart Healthcare Purchase\nFor medical buyers and respiratory specialists, Glycopyrrolate Formoterol Fumarate and Budesonide Inhalation offers:\n\n\nTriple mechanism support\n\n\nTrusted respiratory treatment profile\n\n\nStrong prescription demand\n\n\nGrowing market acceptance\n\n\nLong-term patient care utility\n\n\nConclusion\nIf you are searching for an advanced respiratory maintenance solution, Glycopyrrolate Formoterol Fumarate and Budesonide Inhalation delivers comprehensive airway support through bronchodilation and anti-inflammatory action. Whether for hospital procurement, pharmacy distribution, or physician prescribing needs, this triple-combination inhalation remains a high-demand therapeutic option in respiratory medicine.\n", "price": 885.0, "discountamount": 266.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2417, "imageuri": "https://productimages.withfloats.com/actual/6a03166ee67a7c906d87cf8d.png", "tileimageuri": "https://productimages.withfloats.com/tile/6a03166ee67a7c906d87cf8d.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-05-12T12:00:43.79Z", "updatedon": "2026-06-04T07:57:03.191Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//glycopyrrolate-formoterol-fumarate-and-budesonide-inhalation/2417", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "BUDEPRESS PLUS INH", "category": "ASTHMARANGE", "tags": [ "glycopyrrolate formoterol fumarate and budesonide inhalation", "buy budesonide glycopyrrolate formoterol fumarate", "budesonide glycopyrrolate formoterol fumarate", "glycopyrrolate formoterol fumarate", "Glycopyrrolate Formoterol Fumarate and Budesonide Inhalation", "Buy Glycopyrrolate Formoterol Budesonide Inhaler Online", "Triple Combination Inhaler for COPD Treatment", "Asthma Treatment Inhaler with Budesonide and Formoterol", "Budesonide Formoterol Glycopyrrolate Inhalation Therapy", "Prescription Inhaler for COPD and Asthma Management", "Glycopyrrolate Formoterol Budesonide Inhaler Product Image", "Best Triple Therapy Inhaler for Breathing Disorders", "Budesonide Glycopyrrolate Formoterol Inhaler for Lung Care", "Budesonide, glycopyrrolate, formoterol brand name", "glycopyrrolate formoterol fumarate and budesonide inhalation in hindi", "glycopyrrolate formoterol fumarate and budesonide inhalation price", "glycopyrrolate formoterol fumarate and budesonide inhalation price in india" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "696f2a8662728a2493fefee6", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Rabeprazole Sodium and Cinitapride Capsules", "description": "Rabeprazole Sodium and Cinitapride Capsules (RABISTRUM CT): Complete Product Overview\n\nDigestive disorders such as acidity, gastroesophageal reflux disease (GERD), and functional dyspepsia have become increasingly common due to changing lifestyles, stress, irregular eating habits, and dietary choices. These conditions not only cause discomfort but can significantly affect daily life, sleep quality, and overall well-being. Rabeprazole Sodium and Cinitapride Capsules, marketed under the brand name RABISTRUM CT, offer an advanced and effective solution for managing acid-related and motility-related gastrointestinal disorders.\n\nRABISTRUM CT combines two proven medicines that work together to reduce stomach acid production and improve digestive movement, providing faster and longer-lasting relief from symptoms such as heartburn, bloating, nausea, and indigestion.\n\nWhat is RABISTRUM CT?\n\nRABISTRUM CT is a fixed-dose combination of:\n\nRabeprazole Sodium – a proton pump inhibitor (PPI)\n\nCinitapride – a prokinetic agent\n\nThis dual-action formulation is designed to address both the excess acid production and delayed gastric emptying that commonly occur in acid-peptic disorders. By targeting the root causes of digestive discomfort, RABISTRUM CT provides comprehensive relief and promotes better digestive health.\n\nUses of Rabeprazole Sodium and Cinitapride Capsules\n\nRABISTRUM CT is commonly prescribed for the treatment of:\n\nGastroesophageal reflux disease (GERD)\n\nAcid reflux and heartburn\n\nFunctional dyspepsia\n\nChronic gastritis\n\nPeptic ulcer disease\n\nBloating and post-meal fullness\n\nNausea and vomiting related to gastric motility issues\n\nThis combination is particularly beneficial for patients who experience persistent symptoms despite using acid-suppressing therapy alone.\n\nHow RABISTRUM CT Works\n\nRABISTRUM CT works through a dual-mechanism approach that provides effective and balanced digestive relief.\n\nRole of Rabeprazole Sodium\n\nRabeprazole Sodium belongs to the proton pump inhibitor class and works by:\n\nBlocking the final step of acid production in the stomach\n\nReducing excess gastric acid secretion\n\nAllowing healing of inflamed or damaged stomach and esophageal lining\n\nThis helps relieve symptoms such as burning sensation, acid regurgitation, and stomach pain.\n\nRole of Cinitapride\n\nCinitapride is a gastroprokinetic agent that works by:\n\nEnhancing stomach and intestinal motility\n\nImproving gastric emptying\n\nReducing bloating, nausea, and fullness\n\nStrengthening lower esophageal sphincter tone to prevent reflux\n\nTogether, these actions make RABISTRUM CT more effective than single-drug therapy in many digestive conditions.\n\nKey Benefits of RABISTRUM CT\n\nRABISTRUM CT offers several advantages for patients suffering from acid-related and motility disorders:\n\n1. Comprehensive Digestive Relief\n\nBy reducing acid production and improving gut movement, it treats the root cause of symptoms rather than providing temporary relief.\n\n2. Effective Management of GERD\n\nRABISTRUM CT helps control acid reflux, preventing heartburn and acid regurgitation, especially during nighttime.\n\n3. Reduces Bloating and Fullness\n\nCinitapride improves gastric emptying, making patients feel lighter and more comfortable after meals.\n\n4. Faster Symptom Improvement\n\nThe combined action leads to quicker relief compared to monotherapy.\n\n5. Improves Quality of Life\n\nRelief from chronic digestive discomfort helps improve appetite, sleep, and daily functioning.\n\nDosage and Administration\n\nThe dosage of RABISTRUM CT should be determined by a healthcare professional based on the patient’s condition and response to treatment. Generally:\n\nThe capsule is taken once daily, preferably before meals\n\nIt should be swallowed whole with water\n\nDo not crush or chew the capsule\n\nFor best results, patients should follow dietary advice, avoid trigger foods, and maintain regular meal timings.\n\nPossible Side Effects of RABISTRUM CT\n\nLike all medicines, Rabeprazole Sodium and Cinitapride Capsules may cause side effects in some individuals.\n\nCommon Side Effects\n\nHeadache\n\nDiarrhea\n\nNausea\n\nAbdominal discomfort\n\nDry mouth\n\nDizziness\n\nThese side effects are usually mild and tend to resolve as the body adjusts to the medication.\n\nLess Common but Serious Side Effects\n\nPersistent diarrhea\n\nAllergic reactions such as rash or itching\n\nIrregular heartbeat (rare)\n\nLong-term use may affect vitamin B12 absorption\n\nPatients should consult a doctor if side effects persist or worsen.\n\nPrecautions and Warnings\n\nRABISTRUM CT should be used under medical supervision\n\nPatients with liver disease should inform their doctor before use\n\nLong-term use should be monitored to avoid nutritional deficiencies\n\nPregnant and breastfeeding women should consult a healthcare provider\n\nAvoid alcohol as it may worsen stomach irritation\n\nWho Should Use RABISTRUM CT?\n\nRABISTRUM CT is suitable for:\n\nAdults with GERD or chronic acidity\n\nPatients with functional dyspepsia and bloating\n\nIndividuals experiencing delayed gastric emptying\n\nPatients who do not respond adequately to PPIs alone\n\nIt is not recommended for children unless prescribed by a doctor.\n\nLifestyle Tips to Support Treatment\n\nTo enhance the effectiveness of RABISTRUM CT:\n\nEat smaller, frequent meals\n\nAvoid spicy, fatty, and acidic foods\n\nDo not lie down immediately after eating\n\nReduce stress through relaxation techniques\n\nMaintain a healthy weight\n\nConclusion\n\nRabeprazole Sodium and Cinitapride Capsules (RABISTRUM CT) provide a powerful and well-balanced solution for managing acid-related and digestive motility disorders. By combining acid suppression with improved gastric movement, RABISTRUM CT offers faster relief, longer-lasting results, and improved quality of life for patients struggling with chronic digestive discomfort.\n\nWhen used as prescribed and supported by healthy lifestyle choices, RABISTRUM CT becomes a reliable and effective option for comprehensive gastrointestinal care.", "price": 185.0, "discountamount": 55.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2281, "imageuri": "https://productimages.withfloats.com/actual/696f2a88356da1ccb9841c5b.png", "tileimageuri": "https://productimages.withfloats.com/tile/696f2a88356da1ccb9841c5b.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-20T07:11:02.268Z", "updatedon": "2026-03-12T11:25:45.263Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//rabeprazole-sodium-and-cinitapride-capsules/2281", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "RABISTRUM CT", "category": "GASTROLOGYRANGE", "tags": [ "rabeprazole sodium and cinitapride capsules uses", "rabeprazole cinitapride capsule combination", "rabeprazole sodium cinitapride capsules price", "rabeprazole and cinitapride capsules dosage", "rabeprazole cinitapride capsules for acidity", "rabeprazole sodium cinitapride capsules benefits", "best rabeprazole sodium and cinitapride capsules in India", "rabeprazole cinitapride capsules for acid reflux", "rabeprazole sodium and cinitapride capsules for GERD", "rabeprazole cinitapride capsules for indigestion", "rabeprazole sodium and cinitapride capsules side effects", "rabeprazole cinitapride capsules for gas and bloating", "rabeprazole sodium cinitapride capsules for gastritis", "rabeprazole cinitapride capsules for delayed gastric emptying", "rabeprazole sodium and cinitapride capsules for heartburn", "rabeprazole cinitapride capsules for functional dyspepsia", "rabeprazole sodium and cinitapride capsules manufacturer India", "rabeprazole cinitapride capsules pharma company", "rabeprazole sodium and cinitapride capsules wholesale supplier", "rabeprazole cinitapride capsules third party manufacturing", "when to take rabeprazole and cinitapride capsules", "rabeprazole sodium and cinitapride capsules before food", "rabeprazole cinitapride capsules how it works", "rabeprazole sodium cinitapride capsules daily use", "rabeprazole cinitapride capsules for stomach pain" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "696e129c1d5e7fc4677fb603", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "metformin hydrochloride 850 mg and Glimepiride 2 mg", "description": "Diabetes mellitus is one of the most common chronic lifestyle disorders worldwide, affecting millions of people and requiring long-term management. Type 2 diabetes, in particular, occurs when the body either does not produce enough insulin or cannot use insulin effectively. To manage this condition successfully, combination therapy is often recommended when a single medicine is not sufficient to control blood sugar levels.\n\nMetformin Hydrochloride 850 mg and Glimepiride 2 mg Tablets, marketed under the brand name SEIZMET G2 850, is a well-established and effective oral anti-diabetic combination. It is designed to control blood glucose levels through dual action, addressing both insulin resistance and inadequate insulin secretion.\n\nWhat is SEIZMET G2 850?\n\nSEIZMET G2 850 is a combination of two powerful anti-diabetic agents:\n\nMetformin Hydrochloride 850 mg\n\nGlimepiride 2 mg\n\nThis combination is widely prescribed for adults with Type 2 diabetes mellitus when diet, exercise, and monotherapy do not provide adequate glycemic control. By combining two complementary mechanisms, SEIZMET G2 850 helps achieve better and more stable blood sugar management.\n\nUses of Metformin Hydrochloride 850 mg and Glimepiride 2 mg Tablets\n\nThe primary use of SEIZMET G2 850 is the management of Type 2 diabetes mellitus. It is prescribed to:\n\nLower elevated blood glucose levels\n\nImprove insulin sensitivity\n\nEnhance insulin secretion from the pancreas\n\nPrevent diabetes-related complications\n\nThis medicine is especially beneficial for patients who experience persistent high blood sugar despite lifestyle modifications or single-drug therapy.\n\nHow SEIZMET G2 850 Works\n\nSEIZMET G2 850 works through a dual-action mechanism, ensuring effective blood sugar control throughout the day.\n\nRole of Metformin Hydrochloride\n\nMetformin primarily works by:\n\nReducing glucose production in the liver\n\nImproving insulin sensitivity in muscle and fat tissues\n\nDecreasing glucose absorption from the intestine\n\nIt does not cause excessive insulin release, which makes it less likely to cause hypoglycemia when used alone.\n\nRole of Glimepiride\n\nGlimepiride belongs to the sulfonylurea class and works by:\n\nStimulating the pancreas to release insulin\n\nImproving the body’s response to insulin\n\nLowering post-meal blood sugar spikes\n\nTogether, these actions make SEIZMET G2 850 a comprehensive and balanced treatment option for diabetes control.\n\nKey Benefits of SEIZMET G2 850\n\nSEIZMET G2 850 offers several important benefits for patients with Type 2 diabetes:\n\n1. Effective Blood Sugar Control\n\nThe combination ensures both fasting and post-prandial glucose levels remain within the target range.\n\n2. Dual Mechanism for Better Results\n\nBy addressing insulin resistance and insulin deficiency simultaneously, it provides superior glycemic control compared to single-drug therapy.\n\n3. Reduces Risk of Diabetes Complications\n\nProper blood sugar control helps reduce the risk of complications such as nerve damage, kidney disease, eye problems, and cardiovascular disorders.\n\n4. Improves Quality of Life\n\nStable glucose levels lead to better energy levels, improved well-being, and fewer diabetes-related symptoms.\n\n5. Convenient Combination Therapy\n\nCombining two medicines in one tablet improves patient compliance and simplifies daily medication routines.\n\nDosage and Administration\n\nThe dosage of SEIZMET G2 850 should be determined by a healthcare professional based on:\n\nBlood glucose levels\n\nAge and body weight\n\nKidney and liver function\n\nIndividual response to treatment\n\nThe tablet is usually taken once or twice daily with meals to reduce the risk of stomach upset and hypoglycemia. Patients should take the medicine at the same time each day for best results.\n\nIt is important to follow dietary advice, regular exercise, and blood glucose monitoring alongside medication.\n\nPossible Side Effects of SEIZMET G2 850\n\nLike all medicines, Metformin Hydrochloride 850 mg and Glimepiride 2 mg Tablets may cause side effects in some individuals.\n\nCommon Side Effects\n\nNausea\n\nDiarrhea\n\nAbdominal discomfort\n\nHeadache\n\nDizziness\n\nThese side effects are usually mild and temporary and often improve as the body adjusts to the medication.\n\nLess Common but Serious Side Effects\n\nHypoglycemia (low blood sugar), especially if meals are skipped\n\nLactic acidosis (rare but serious, associated with metformin)\n\nAllergic reactions such as skin rash or itching\n\nLiver function abnormalities\n\nPatients should seek medical attention if they experience symptoms such as excessive sweating, confusion, extreme weakness, breathing difficulty, or persistent stomach pain.\n\nPrecautions and Warnings\n\nSEIZMET G2 850 should be used only under medical supervision.\n\nPatients with kidney, liver, or heart disease should inform their doctor before use.\n\nAlcohol consumption should be avoided, as it may increase the risk of side effects.\n\nPregnant and breastfeeding women should consult their doctor before taking this medicine.\n\nRegular monitoring of blood sugar levels is essential to avoid hypoglycemia or uncontrolled diabetes.\n\nWho Should Use SEIZMET G2 850?\n\nSEIZMET G2 850 is suitable for:\n\nAdults diagnosed with Type 2 diabetes\n\nPatients inadequately controlled on metformin or glimepiride alone\n\nIndividuals requiring combination therapy for better glycemic control\n\nIt is not recommended for Type 1 diabetes or diabetic ketoacidosis.\n\nConclusion\n\nMetformin Hydrochloride 850 mg and Glimepiride 2 mg Tablets (SEIZMET G2 850) is a trusted and effective combination therapy for the management of Type 2 diabetes mellitus. By combining the benefits of metformin and glimepiride, it offers comprehensive blood sugar control, reduces the risk of long-term complications, and improves overall quality of life.", "price": 102.0, "discountamount": 30.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2280, "imageuri": "https://productimages.withfloats.com/actual/696e12d9cb45a8390116f1bf.png", "tileimageuri": "https://productimages.withfloats.com/tile/696e12d9cb45a8390116f1bf.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-19T11:16:44.772Z", "updatedon": "2026-03-13T11:01:31.908Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//metformin-hydrochloride-850-mg-and-glimepiride-2-mg/2280", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "SEIZMET G2 850", "category": "DIABETIC RANGE", "tags": [ "metformin hydrochloride 850 mg and glimepiride 2 mg tablets", "metformin 850 mg glimepiride 2 mg combination tablet", "glimepiride 2 mg with metformin 850 mg tablets", "metformin glimepiride fixed dose combination tablets", "metformin 850 mg glimepiride 2 mg dosage", "metformin glimepiride tablets for type 2 diabetes", "metformin and glimepiride tablets uses in diabetes", "metformin 850 mg glimepiride 2 mg for blood sugar control", "metformin glimepiride tablets mechanism of action", "metformin glimepiride tablets benefits", "metformin 850 mg glimepiride 2 mg side effects", "metformin glimepiride tablets precautions", "glimepiride metformin tablets safety in diabetes", "metformin glimepiride tablets contraindications", "metformin glimepiride tablets warnings", "metformin glimepiride tablets dosage guidelines", "how to take metformin 850 mg and glimepiride 2 mg tablets", "metformin glimepiride tablets before or after food", "metformin glimepiride tablets daily dose", "metformin glimepiride tablets price in India" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69623e6c95697555dd1afd67", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Esomeprazole and Itopride", "description": "ESMOSTRUM IT: Comprehensive Product Guide\nProduct Overview\nESMOSTRUM IT is an advanced pharmaceutical formulation that combines two potent active ingredients—Esomeprazole and Itopride—to provide comprehensive relief from gastrointestinal disorders. This dual-action medication represents a significant advancement in the management of acid-related digestive conditions and motility disorders. By combining a proton pump inhibitor with a prokinetic agent, ESMOSTRUM IT addresses both the underlying causes and symptomatic manifestations of various digestive ailments, offering patients a complete therapeutic solution in a single, convenient dosage form.\nThe synergistic combination of Esomeprazole and Itopride makes ESMOSTRUM IT particularly effective for individuals suffering from gastroesophageal reflux disease (GERD), functional dyspepsia, and other conditions where both excessive acid production and impaired gastric motility contribute to discomfort and disease progression.\nActive Pharmaceutical Ingredients\nEsomeprazole\nEsomeprazole is the S-isomer of omeprazole and belongs to the class of medications known as proton pump inhibitors (PPIs). It works by specifically and irreversibly blocking the hydrogen-potassium adenosine triphosphatase enzyme system (the proton pump) located in the gastric parietal cells. This mechanism effectively reduces gastric acid secretion, providing sustained relief from acid-related symptoms and allowing damaged esophageal and gastric tissue to heal.\nItopride\nItopride is a prokinetic agent that enhances gastrointestinal motility through a dual mechanism of action. It acts as both a dopamine D2 receptor antagonist and an acetylcholinesterase inhibitor. By blocking dopamine receptors, it removes the inhibitory effect of dopamine on gastrointestinal motility, while its acetylcholinesterase inhibition increases acetylcholine levels, further promoting coordinated gastric contractions and improved gastric emptying.\nTherapeutic Uses and Indications\nESMOSTRUM IT is prescribed for a wide range of gastrointestinal conditions where both acid suppression and enhanced motility are therapeutically beneficial:\nGastroesophageal Reflux Disease (GERD)\nESMOSTRUM IT provides exceptional relief for patients suffering from GERD, a chronic condition where stomach acid frequently flows back into the esophagus. The esomeprazole component reduces acid production, while itopride improves the tone of the lower esophageal sphincter and accelerates gastric emptying, thereby reducing the frequency and severity of reflux episodes.\nFunctional Dyspepsia\nFor patients experiencing persistent or recurrent upper abdominal discomfort without an identifiable organic cause, ESMOSTRUM IT addresses multiple pathophysiological mechanisms. It relieves symptoms such as early satiety, postprandial fullness, epigastric pain, and bloating by normalizing gastric acid levels and improving gastric accommodation and emptying.\nPeptic Ulcer Disease\nESMOSTRUM IT aids in the healing of gastric and duodenal ulcers by creating an optimal healing environment through sustained acid suppression. The prokinetic action of itopride helps prevent stasis of gastric contents, which can exacerbate ulcer symptoms.\nNon-Ulcer Dyspepsia\nMany patients experience dyspeptic symptoms without evidence of ulceration. ESMOSTRUM IT effectively manages these symptoms by addressing both acid hypersecretion and delayed gastric emptying, two key factors in non-ulcer dyspepsia.\nGastroparesis-Related Symptoms\nIn conditions where gastric emptying is significantly delayed, the itopride component of ESMOSTRUM IT helps restore more normal gastric motility patterns, reducing associated symptoms like nausea, vomiting, and abdominal distension.\nKey Benefits and Advantages\nDual Mechanism of Action\nThe primary advantage of ESMOSTRUM IT lies in its comprehensive approach to gastrointestinal health. Rather than addressing only acid production or motility in isolation, this combination therapy tackles both aspects simultaneously, providing more complete symptom relief and better therapeutic outcomes.\nSuperior Acid Suppression\nEsomeprazole offers more consistent and prolonged acid suppression compared to many other acid-reducing medications. It provides sustained relief throughout the day and night, allowing patients to experience fewer breakthrough symptoms and better quality of life.\nEnhanced Gastric Motility\nThe itopride component specifically targets motility issues without crossing the blood-brain barrier significantly, meaning it provides prokinetic benefits with minimal central nervous system side effects. This results in improved gastric emptying, reduced bloating, and decreased feelings of fullness after meals.\nRapid Symptom Relief\nMany patients experience noticeable improvement in their symptoms within the first few days of treatment with ESMOSTRUM IT. The combination therapy addresses multiple symptom pathways simultaneously, leading to faster and more comprehensive relief.\nImproved Quality of Life\nBy effectively managing symptoms such as heartburn, regurgitation, nausea, bloating, and early satiety, ESMOSTRUM IT significantly enhances patients' daily functioning and overall well-being. Patients report better sleep quality, improved dietary tolerance, and reduced anxiety related to their digestive symptoms.\nConvenient Dosing\nThe combination of two active ingredients in a single formulation improves medication adherence by reducing pill burden. Patients appreciate the simplicity of taking one medication instead of multiple separate preparations.\nMucosal Healing Properties\nBeyond symptom relief, ESMOSTRUM IT promotes actual healing of damaged esophageal and gastric mucosa. The reduced acid environment created by esomeprazole allows inflamed and eroded tissue to regenerate properly.\nReduced Risk of Complications\nBy effectively controlling acid reflux and improving gastric emptying, ESMOSTRUM IT helps prevent potential complications of chronic GERD, such as esophageal strictures, Barrett's esophagus, and respiratory complications from aspiration.\nDosage and Administration\nESMOSTRUM IT should be taken exactly as prescribed by a healthcare professional. Typically, the medication is administered orally, preferably before meals to optimize its therapeutic effects. The standard dosing regimen usually involves once or twice daily administration, though individual requirements may vary based on the severity of the condition and patient response.\nThe medication should be swallowed whole with water and should not be crushed, chewed, or split, as this may affect the drug's release mechanism and therapeutic efficacy. Patients should maintain regular dosing schedules to ensure optimal acid suppression and motility enhancement throughout the day.\nSide Effects and Safety Considerations\nLike all medications, ESMOSTRUM IT may cause side effects in some individuals, though not everyone experiences them. Understanding potential adverse effects helps patients identify and report concerning symptoms promptly.\nCommon Side Effects\nGastrointestinal Effects: Some patients may experience diarrhea, constipation, abdominal pain, nausea, or flatulence, particularly during initial treatment. These effects are usually mild and often resolve as the body adjusts to the medication.\nHeadache: Mild to moderate headaches occur in a small percentage of patients and typically diminish with continued use.\nDizziness: Some individuals may experience lightheadedness or dizziness, particularly when standing up quickly.\nDry Mouth: Reduced saliva production may occur, leading to oral dryness and discomfort.\nLess Common Side Effects\nSkin Reactions: Rash, itching, or other dermatological manifestations may develop in sensitive individuals.\nSleep Disturbances: Some patients report insomnia or unusual dreams while taking the medication.\nIncreased Prolactin Levels: Itopride may cause mild elevation in prolactin levels, though clinical manifestations are rare.\nTaste Alterations: Changes in taste perception or metallic taste may occur temporarily.\nSerious Side Effects (Rare)\nWhile uncommon, certain serious adverse effects require immediate medical attention:\n\nSevere allergic reactions including difficulty breathing, facial swelling, or severe skin reactions\nSevere diarrhea that persists or contains blood\nIrregular heartbeat or palpitations\nMuscle weakness or pain\nSeizures or tremors\nSigns of liver problems including jaundice, dark urine, or persistent nausea\n\nLong-Term Considerations\nExtended use of proton pump inhibitors like esomeprazole has been associated with certain risks that patients should discuss with their healthcare providers:\n\nPotential reduction in calcium, magnesium, and vitamin B12 absorption\nSlightly increased risk of bone fractures with prolonged use\nPossible increased susceptibility to certain gastrointestinal infections\nRare cases of kidney problems\n\nRegular monitoring and periodic assessment by healthcare professionals help minimize these risks while maintaining therapeutic benefits.\nPrecautions and Contraindications\nPatients should inform their healthcare provider about all existing medical conditions, particularly liver disease, kidney problems, osteoporosis, low magnesium levels, or any gastrointestinal bleeding. ESMOSTRUM IT may interact with certain medications, including blood thinners, antifungals, HIV medications, and certain antibiotics. A complete medication review ensures safe and effective therapy.\nPregnant or breastfeeding women should only use ESMOSTRUM IT under strict medical supervision, as the safety profile in these populations requires careful consideration of potential risks and benefits.\nLifestyle Recommendations\nFor optimal therapeutic outcomes, patients taking ESMOSTRUM IT should complement their medication regimen with appropriate lifestyle modifications:\n\nAvoid trigger foods that exacerbate acid reflux, such as spicy foods, citrus, chocolate, caffeine, and alcohol\nMaintain a healthy body weight to reduce abdominal pressure\nEat smaller, more frequent meals rather than large portions\nAvoid lying down immediately after eating; wait at least two to three hours\nElevate the head of the bed if nighttime symptoms occur\nQuit smoking, as tobacco use significantly worsens reflux symptoms\nManage stress through relaxation techniques, as stress can exacerbate digestive symptoms\n\nConclusion\nESMOSTRUM IT represents a sophisticated and effective pharmaceutical solution for individuals struggling with complex gastrointestinal disorders involving both acid hypersecretion and impaired motility. By combining the powerful acid-suppressing capabilities of esomeprazole with the prokinetic benefits of itopride, this medication offers comprehensive symptom management that addresses the multifaceted nature of digestive disorders.", "price": 182.0, "discountamount": 54.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2273, "imageuri": "https://productimages.withfloats.com/actual/69623e6fd8491171373812e3.png", "tileimageuri": "https://productimages.withfloats.com/tile/69623e6fd8491171373812e3.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-10T11:56:28.061Z", "updatedon": "2026-04-21T09:38:56.999Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//esomeprazole-and-itopride/2273", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "ESMOSTRUM IT", "category": "GASTROLOGYRANGE", "tags": [ "esomeprazole and itopride", "esomeprazole and itopride capsules uses in hindi", "esomeprazole and itopride capsules uses", "esomeprazole and itopride brand name", "esomeprazole and itopride hydrochloride", "esomeprazole and itopride capsules", "esomeprazole and itopride uses", "esomeprazole and itopride hydrochloride capsules", "esomeprazole and itopride hydrochloride uses", "esomeprazole and itopride hydrochloride price", "esomeprazole and itopride hydrochloride price in india", "buy online Esomeprazole and Itopride" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "695b65af2800555f6696a6cf", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Cinacalcet 60 mg Tablet", "description": "CINASELECT 60: Comprehensive Guide to Cinacalcet 60 mg Tablets\nProduct Overview\nCINASELECT 60 is a pharmaceutical formulation containing Cinacalcet hydrochloride 60 mg as its active ingredient. This medication represents a significant advancement in the management of calcium metabolism disorders, particularly in patients with chronic kidney disease and parathyroid conditions. As a calcimimetic agent, CINASELECT 60 works by mimicking the action of calcium on tissues, helping to restore hormonal balance and mineral homeostasis in the body.\nThe 60 mg dosage strength offers an effective therapeutic option for patients requiring moderate to higher-level intervention in managing parathyroid hormone levels and associated calcium imbalances. CINASELECT 60 is manufactured under strict quality control standards, ensuring consistency, purity, and efficacy in every tablet.\nUnderstanding How CINASELECT 60 Works\nCINASELECT 60 operates through a sophisticated mechanism that targets the calcium-sensing receptors located on the surface of parathyroid gland cells. These receptors play a crucial role in regulating parathyroid hormone secretion, which in turn controls calcium and phosphorus levels in the bloodstream.\nWhen you take CINASELECT 60, the active ingredient cinacalcet binds to these calcium-sensing receptors, increasing their sensitivity to extracellular calcium. This enhanced sensitivity tricks the parathyroid glands into “thinking” there is more calcium present in the blood than there actually is. As a result, the glands reduce their production and release of parathyroid hormone (PTH).\nBy lowering PTH levels, CINASELECT 60 subsequently reduces calcium levels in the blood and decreases the amount of phosphorus absorbed from the intestines. This cascade effect helps restore the delicate mineral balance that is often disrupted in patients with kidney disease or parathyroid disorders.\nPrimary Therapeutic Uses\nSecondary Hyperparathyroidism in Chronic Kidney Disease\nThe primary indication for CINASELECT 60 is the treatment of secondary hyperparathyroidism in adult patients with chronic kidney disease (CKD) who are on dialysis. When kidneys fail to function properly, they cannot adequately regulate calcium and phosphorus levels, leading to excessive parathyroid hormone production. This condition can result in serious complications including bone disease, cardiovascular calcification, and increased mortality risk.\nCINASELECT 60 helps manage this condition by controlling PTH levels, thereby reducing the risk of bone complications such as osteitis fibrosa cystica and preventing the dangerous deposition of calcium in blood vessels and soft tissues.\nHypercalcemia in Parathyroid Carcinoma\nCINASELECT 60 is also indicated for treating hypercalcemia (elevated blood calcium levels) in patients with parathyroid carcinoma, a rare malignant tumor of the parathyroid glands. In these cases, the medication helps control the dangerously high calcium levels that can lead to kidney stones, bone pain, digestive issues, and neurological symptoms.\nPrimary Hyperparathyroidism\nFor patients with severe hypercalcemia due to primary hyperparathyroidism who cannot undergo parathyroidectomy or for whom surgery has failed, CINASELECT 60 offers a valuable medical management option. This provides relief for patients who are not surgical candidates due to advanced age, comorbidities, or other contraindications.\nKey Benefits of CINASELECT 60\nEffective PTH Control\nClinical studies have demonstrated that CINASELECT 60 significantly reduces parathyroid hormone levels in a dose-dependent manner. This reduction helps prevent the cascade of complications associated with elevated PTH, including bone mineral loss and cardiovascular calcification.\nImproved Calcium-Phosphorus Balance\nBy reducing PTH secretion, CINASELECT 60 helps normalize serum calcium and phosphorus levels. This is particularly important in dialysis patients, where mineral imbalances can lead to serious complications affecting bone health, cardiovascular function, and overall quality of life.\nReduced Cardiovascular Risk\nElevated calcium and phosphorus levels contribute to vascular calcification, a major risk factor for cardiovascular disease in patients with chronic kidney disease. By managing these mineral levels, CINASELECT 60 may help reduce the risk of cardiovascular complications, which are the leading cause of death in dialysis patients.\nBone Health Preservation\nUncontrolled secondary hyperparathyroidism leads to renal osteodystrophy, a condition characterized by abnormal bone metabolism. CINASELECT 60 helps protect bone integrity by normalizing PTH levels, potentially reducing fracture risk and preserving bone mineral density.\nAlternative to Surgery\nFor patients with primary hyperparathyroidism or parathyroid carcinoma who cannot undergo surgery, CINASELECT 60 provides an effective medical management option. This is particularly valuable for elderly patients or those with multiple comorbidities that make surgery risky.\nQuality of Life Improvement\nBy controlling symptoms associated with hypercalcemia and hyperparathyroidism, such as bone pain, muscle weakness, fatigue, and digestive issues, CINASELECT 60 can significantly improve patients' overall quality of life and functional capacity.\nConvenient Oral Administration\nCINASELECT 60 is administered orally, making it more convenient than injectable alternatives. This allows for outpatient management and reduces the burden on healthcare facilities and patients.\nPotential Side Effects and Adverse Reactions\nCommon Side Effects\nPatients taking CINASELECT 60 may experience several common side effects, which typically include nausea and vomiting, occurring in approximately 20-30% of patients. These gastrointestinal symptoms are usually mild to moderate and may improve over time as the body adjusts to the medication.\nDiarrhea is another frequent complaint, affecting roughly 20% of users. Some patients also report muscle pain or myalgia, dizziness, loss of appetite, and asthenia (general weakness or fatigue).\nSerious Side Effects Requiring Medical Attention\nHypocalcemia: The most significant risk associated with CINASELECT 60 is the development of low calcium levels in the blood. Severe hypocalcemia can lead to paresthesias (tingling sensations), muscle cramps or spasms, tetany, seizures, and QT interval prolongation on electrocardiogram, which can predispose to dangerous heart rhythm abnormalities.\nGastrointestinal Bleeding: There have been reports of gastrointestinal hemorrhage in patients taking cinacalcet, particularly in those with risk factors such as gastritis, ulcers, or concurrent use of other medications that increase bleeding risk.\nAdynamic Bone Disease: Oversuppression of PTH can lead to adynamic bone disease, a condition where bone turnover becomes abnormally low, potentially weakening bones despite normalized calcium levels.\nCardiovascular Effects: Some patients may experience worsening heart failure or arrhythmias, particularly if hypocalcemia develops. Close monitoring is essential in patients with underlying cardiovascular disease.\nAllergic Reactions: Though rare, hypersensitivity reactions including rash, urticaria, and angioedema have been reported.\nPrecautions and Contraindications\nCINASELECT 60 should not be used in patients with serum calcium levels below the normal range. It requires careful dose adjustment and monitoring in patients with hepatic impairment. The medication may interact with drugs metabolized by the CYP2D6 enzyme system and with medications that affect gastric pH.\nPregnant or breastfeeding women should use CINASELECT 60 only if clearly needed, as its safety in these populations has not been fully established. Regular monitoring of serum calcium, phosphorus, and PTH levels is essential throughout treatment.\nDosage and Administration Guidelines\nCINASELECT 60 should be taken orally with food or shortly after a meal, as this improves absorption and reduces gastrointestinal side effects. Tablets should be swallowed whole and not crushed, chewed, or divided.\nThe typical starting dose for secondary hyperparathyroidism is lower than 60 mg, with gradual titration based on PTH and calcium levels. The 60 mg strength is often used as part of the dose escalation process or as a maintenance dose once optimal PTH control is achieved.\nDose adjustments should be made no more frequently than every two to four weeks, as it takes this long to see the full effect of a dose change on PTH levels. Treatment should be individualized based on laboratory values and clinical response.\nMonitoring Requirements\nPatients on CINASELECT 60 require regular monitoring of serum calcium, phosphorus, and intact PTH levels. Calcium levels should be checked within one week of starting treatment or after any dose adjustment, and then monthly once stable. PTH levels should be measured one to four weeks after initiation or dose adjustment, then every one to three months during maintenance therapy.\nAdditionally, patients should be monitored for signs and symptoms of hypocalcemia, particularly during the initial treatment period. Electrocardiogram monitoring may be appropriate in patients at risk for QT prolongation.\nStorage and Handling\nCINASELECT 60 should be stored at room temperature, away from moisture and direct sunlight. The medication should be kept in its original container with the lid tightly closed to protect from humidity. Keep out of reach of children and pets. Do not use past the expiration date printed on the package.\nConclusion\nCINASELECT 60 (Cinacalcet 60 mg) represents a valuable therapeutic option in the management of secondary hyperparathyroidism associated with chronic kidney disease, hypercalcemia in parathyroid carcinoma, and primary hyperparathyroidism in patients who cannot undergo surgery. Its unique mechanism as a calcimimetic agent provides effective control of parathyroid hormone secretion, helping to restore mineral balance and prevent serious complications.\nThe benefits of CINASELECT 60 extend beyond simple laboratory value normalization. By controlling PTH, calcium, and phosphorus levels, this medication helps preserve bone health, reduce cardiovascular calcification risk, and improve overall quality of life for patients dealing with complex metabolic disorders. For patients who are not surgical candidates, CINASELECT 60 offers hope and effective symptom management.\nHowever, like all medications, CINASELECT 60 must be used judiciously under close medical supervision. The risk of hypocalcemia and other potential side effects necessitates regular laboratory monitoring and open communication between patients and healthcare providers. Patients should report any concerning symptoms promptly and attend all scheduled follow-up appointments.", "price": 740.0, "discountamount": 222.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2266, "imageuri": "https://productimages.withfloats.com/actual/695b65ebf30763183f64d4f7.png", "tileimageuri": "https://productimages.withfloats.com/tile/695b65ebf30763183f64d4f7.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-05T07:18:07.264Z", "updatedon": "2026-05-01T06:30:26.075Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//cinacalcet-60-mg-tablet/2266", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CINASELECT 60", "category": "NEPHROLOGYRANGE", "tags": [ "cinacalcet 60 mg", "cinacalcet mechanism of action.", "cinacalcet uses", "tab cinacalcet.", "cinacalcet dose.", "cinacalcet structure.", "cinacalcet tab.", "calcium and phosphorus levels in the bloodstream.", "parathyroid hormone secretion.", "calcium metabolism disorders.", "chronic kidney disease and parathyroid conditions.", "cinacalcet 60 mg", "cinacalcet 60", "Cinacalcet Tablets 60 mg price in India", "Buy Cinacalcet Tablets 60 mg online", "Cinacalcet 60 mg wholesale price", "Buy Cinacalcet Tablets 60 mg", "Get Cinacalcet Tablets 60 mg at best price" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "694cf85408591c1173b54c2f", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Pregabalin Epalrestat and Methylcobalamin Tablets", "description": "EPSTATE ED represents an advanced pharmaceutical formulation that combines three powerful therapeutic agents: Pregabalin, Epalrestat, and Methylcobalamin. This innovative triple-combination medication is specifically designed to address the complex pathophysiology of diabetic neuropathy and neuropathic pain conditions. By integrating multiple mechanisms of action, EPSTATE ED offers a comprehensive approach to managing nerve-related complications that significantly impact the quality of life for millions of individuals worldwide.\nThe formulation addresses not only the symptomatic relief of neuropathic pain but also targets the underlying metabolic derangements that contribute to nerve damage progression. This multi-pronged therapeutic strategy makes EPSTATE ED particularly valuable for patients who require more than symptomatic management alone.\nUnderstanding the Active Components\nPregabalin: The Neuropathic Pain Modulator\nPregabalin serves as the cornerstone analgesic component in EPSTATE ED. This anticonvulsant medication works by binding to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. Through this mechanism, Pregabalin reduces the release of excitatory neurotransmitters including glutamate, norepinephrine, and substance P. This reduction in neurotransmitter release effectively dampens the abnormal neural signaling that characterizes neuropathic pain conditions.\nThe molecule demonstrates excellent bioavailability and rapid absorption, allowing patients to experience relief within a relatively short timeframe. Its efficacy in managing various neuropathic pain syndromes has been extensively documented in clinical trials, establishing it as a first-line agent for diabetic peripheral neuropathy, postherpetic neuralgia, and other chronic neuropathic pain conditions.\nEpalrestat: The Aldose Reductase Inhibitor\nEpalrestat represents a unique addition to the formulation, functioning as a selective aldose reductase inhibitor. In diabetic conditions, excess glucose is converted to sorbitol through the polyol pathway, with aldose reductase serving as the rate-limiting enzyme. The accumulation of sorbitol within nerve cells leads to osmotic stress, depletion of myoinositol, and subsequent nerve dysfunction.\nBy inhibiting aldose reductase, Epalrestat prevents this harmful sorbitol accumulation, thereby addressing one of the fundamental metabolic abnormalities responsible for diabetic neuropathy. This disease-modifying approach distinguishes EPSTATE ED from purely symptomatic treatments. Epalrestat has been particularly well-studied in Asian populations and has demonstrated the ability to improve nerve conduction velocities and reduce subjective neuropathic symptoms over time.\nMethylcobalamin: The Neurotropic Vitamin\nMethylcobalamin, the bioactive form of Vitamin B12, completes the therapeutic triad in EPSTATE ED. Unlike cyanocobalamin, which requires conversion in the body, methylcobalamin is immediately available for utilization in crucial biochemical processes. It plays an indispensable role in myelin synthesis, the protective sheath surrounding nerve fibers that enables proper signal transmission.\nThis coenzyme participates in methionine synthesis and is essential for maintaining the structural and functional integrity of neurons. Methylcobalamin also facilitates nerve regeneration and has demonstrated neuroprotective properties in various experimental models. For patients with diabetic neuropathy, who often exhibit Vitamin B12 deficiency (sometimes exacerbated by metformin therapy), supplementation with methylcobalamin addresses both nutritional deficits and supports nerve health at a fundamental level.\nClinical Applications and Uses\nEPSTATE ED is primarily indicated for the comprehensive management of diabetic peripheral neuropathy, a condition affecting approximately 50% of individuals with long-standing diabetes. The symptoms of this condition range from tingling sensations and burning pain to numbness and loss of protective sensation, which can lead to serious complications including foot ulcers and amputations.\nBeyond diabetic neuropathy, EPSTATE ED may be prescribed for various neuropathic pain syndromes where the combination of pain relief, metabolic correction, and nerve support proves beneficial. Patients experiencing chronic nerve pain resulting from metabolic disturbances, nutritional deficiencies, or structural nerve damage may find this combination particularly effective.\nThe medication is typically recommended for adults who have not achieved adequate symptom control with single-agent therapy or who would benefit from the synergistic effects of the three components. Healthcare providers may prescribe EPSTATE ED when a patient requires both immediate symptom relief and long-term disease modification.\nKey Benefits and Therapeutic Advantages\nComprehensive Multi-Mechanism Action\nThe primary advantage of EPSTATE ED lies in its multi-faceted approach to neuropathic conditions. Rather than addressing only pain symptoms, the formulation simultaneously tackles pain perception, underlying metabolic abnormalities, and nutritional support for nerve health. This comprehensive strategy may lead to superior outcomes compared to monotherapy approaches.\nEnhanced Pain Relief\nClinical evidence supporting Pregabalin's efficacy in neuropathic pain is substantial. Patients often report significant reductions in pain intensity, improved sleep quality due to decreased nocturnal pain, and enhanced ability to perform daily activities. The pain-relieving effects typically manifest within the first week of therapy and continue to improve with ongoing treatment.\nDisease Modification Potential\nUnlike purely symptomatic treatments, the inclusion of Epalrestat provides genuine disease-modifying potential. By targeting the polyol pathway, EPSTATE ED may slow the progression of nerve damage in diabetic patients. Long-term use may preserve nerve function and prevent the worsening of neuropathic symptoms, offering hope beyond mere symptom management.\nImproved Nerve Conduction and Function\nThe combination of metabolic correction through Epalrestat and neurotropic support via Methylcobalamin creates an environment conducive to nerve regeneration and functional improvement. Studies have demonstrated improvements in nerve conduction velocity parameters with similar combination therapies, suggesting potential restoration of nerve function rather than simple symptom masking.\nConvenience of Combination Therapy\nFor patients who would otherwise require multiple separate medications, EPSTATE ED offers the convenience of a single tablet containing all three therapeutic agents. This simplification of medication regimens improves compliance, reduces pill burden, and may enhance overall treatment outcomes.\nQuality of Life Enhancement\nThe cumulative effect of pain reduction, improved nerve function, and better metabolic control translates into meaningful quality of life improvements. Patients report better mobility, reduced interference of pain with daily activities, improved mood, and enhanced social functioning.\nPotential Side Effects and Safety Considerations\nCommon Side Effects\nAs with any pharmaceutical agent, EPSTATE ED may produce certain adverse effects. The most commonly reported side effects are primarily attributable to the Pregabalin component and include dizziness, somnolence, peripheral edema, dry mouth, blurred vision, weight gain, and difficulty with concentration or attention. These effects are generally mild to moderate and often diminish with continued therapy as the body adapts to the medication.\nGastrointestinal symptoms such as constipation or nausea may occur, though they are typically manageable with dietary modifications or symptomatic treatment. Some patients experience increased appetite leading to weight gain, which requires monitoring, particularly in diabetic individuals where weight management is crucial.\nSerious but Rare Adverse Events\nThough uncommon, certain serious adverse effects warrant immediate medical attention. These include allergic reactions manifesting as rash, itching, swelling, severe dizziness, or breathing difficulties. Pregabalin has been associated with rare cases of angioedema, which requires prompt discontinuation and medical intervention.\nMental health changes, including mood alterations, anxiety, depression, agitation, or suicidal thoughts, have been reported with Pregabalin use, particularly in individuals with pre-existing psychiatric conditions. Patients and caregivers should remain vigilant for behavioral changes and report them immediately to healthcare providers.\nDrug Interactions and Precautions\nEPSTATE ED may interact with other central nervous system depressants, including alcohol, opioids, benzodiazepines, and antihistamines, potentially intensifying sedation and cognitive impairment. Patients should inform their healthcare provider of all medications, supplements, and substances they consume.\nIndividuals with kidney impairment require dose adjustments since Pregabalin is primarily eliminated through renal excretion. Regular monitoring of renal function may be necessary during long-term therapy.\nSpecial Population Considerations\nPregnant or breastfeeding women should use EPSTATE ED only when clearly necessary and under strict medical supervision, as the safety profile in these populations has not been fully established. Elderly patients may be more susceptible to side effects, particularly dizziness and confusion, necessitating careful dose titration and monitoring.\nPatients should be advised against abrupt discontinuation of EPSTATE ED, as sudden cessation of Pregabalin may precipitate withdrawal symptoms including insomnia, nausea, headache, anxiety, and sweating. Gradual dose reduction under medical supervision is recommended when discontinuing therapy.\nDosage and Administration Guidelines\nThe appropriate dosage of EPSTATE ED is highly individualized and should be determined by a qualified healthcare professional based on the patient's specific condition, response to therapy, and tolerance. Typically, treatment begins with a lower dose that is gradually increased to achieve optimal therapeutic benefit while minimizing adverse effects.\nPatients should take EPSTATE ED exactly as prescribed, with or without food, at consistent times each day to maintain stable blood levels. Missing doses should be addressed by taking the forgotten dose as soon as remembered, unless it's nearly time for the next scheduled dose. Double dosing to compensate for missed doses is not recommended.\nRegular follow-up appointments allow healthcare providers to assess treatment efficacy, monitor for adverse effects, and make necessary dose adjustments. Patients should maintain open communication with their medical team regarding symptom improvement, side effects, and any concerns that arise during therapy.\nPatient Counseling and Lifestyle Recommendations\nMaximizing the benefits of EPSTATE ED extends beyond simply taking the medication. Patients should be counseled on complementary lifestyle measures that support neuropathy management. Maintaining optimal glycemic control remains paramount for diabetic patients, as blood sugar management directly impacts neuropathy progression regardless of medication.\nRegular physical activity, within individual capabilities, promotes circulation, supports nerve health, and may enhance the therapeutic effects of EPSTATE ED. Daily foot examinations become critical for diabetic patients to identify potential injuries early, preventing serious complications.\nNutritional optimization, including adequate intake of B vitamins, antioxidants, and essential nutrients, supports the neurotropic effects of Methylcobalamin. Avoiding alcohol and tobacco, both of which can exacerbate neuropathy, is strongly recommended.\nPatients should be cautioned about activities requiring alertness, such as driving or operating machinery, especially during the initial treatment phase when dizziness and somnolence may be more pronounced. These effects typically improve with continued therapy, but individual responses vary.\nConclusion\nEPSTATE ED represents a thoughtfully designed pharmaceutical formulation that addresses the multifaceted nature of diabetic neuropathy and neuropathic pain through its unique combination of Pregabalin, Epalrestat, and Methylcobalamin. This triple-action approach offers patients more than symptomatic relief—it provides genuine disease modification potential, nutritional support, and comprehensive nerve health optimization.\nThe synergistic effects of these three components create a therapeutic profile that is greater than the sum of its parts. While Pregabalin efficiently manages pain symptoms and improves quality of life in the short term, Epalrestat works to address underlying metabolic derangements that drive disease progression, and Methylcobalamin provides essential neurotropic support for nerve regeneration and function.\nFor patients struggling with the debilitating effects of neuropathic pain and diabetic neuropathy, EPSTATE ED offers renewed hope for better symptom control and potentially slowed disease progression. The convenience of combination therapy in a single tablet improves adherence and simplifies complex treatment regimens.\nHowever, EPSTATE ED is not without considerations. Potential side effects, though generally manageable, require awareness and monitoring. The medication is most effective when integrated into a comprehensive management plan that includes optimal glycemic control, lifestyle modifications, and regular medical supervision.\nUltimately, EPSTATE ED should be viewed as a valuable tool in the therapeutic arsenal against neuropathic conditions, best utilized under the guidance of knowledgeable healthcare professionals who can individualize treatment to each patient's unique needs and circumstances. With proper use, monitoring, and patient education, EPSTATE ED can significantly improve outcomes and quality of life for those affected by these challenging neurological conditions.", "price": 275.0, "discountamount": 82.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2253, "imageuri": "https://productimages.withfloats.com/actual/694cf859d25fa0b0657b1ac8.png", "tileimageuri": "https://productimages.withfloats.com/tile/694cf859d25fa0b0657b1ac8.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-25T08:39:48.947Z", "updatedon": "2026-04-18T09:21:49.885Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//pregabalin-epalrestat-and-methylcobalamin-tablets/2253", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "EPSTATE ED", "category": "NEUROLOGYRANGE", "tags": [ "regabalin, Epalrestat, and Methylcobalamin.neuropathic pain conditions.", "Pregabalin, Epalrestat, and Methylcobalamin.", "neuropathic pain.", "diabetic neuropathy.", "sorbitol within nerve cells leads to osmotic stress.", "Epalrestat and neurotropic support via Methylcobalamin creates an environment .", "mood alterations, anxiety, depression, agitation.", "supports the neurotropic effects of Methylcobalamin.", "Pregabalin Epalrestat and Methylcobalamin Tablets", "epalrestat and methylcobalamin tablets uses", "epalrestat and methylcobalamin tablets in hindi", "pregabalin epalrestat and methylcobalamin tablets price jaipur", "pregabalin epalrestat and methylcobalamin tablets price india" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "691f0bfb7357125af3e94c2b", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Sucralfate Tinidazole and Povidone Iodine Ointment", "description": "Sucralfate, Tinidazole, and Povidone Iodine Ointment is an advanced multi-action topical formulation designed to promote rapid wound healing, prevent infection, and enhance tissue regeneration. This combination therapy is widely used in dermatology, surgery, gynecology, and general wound management due to its broad-spectrum antimicrobial activity and strong healing-supportive characteristics. Each active ingredient plays a unique and complementary role, making this ointment highly effective in managing acute and chronic wounds, ulcers, burns, and infected skin lesions.\n\nAt the core of the formulation, Sucralfate acts as a protective barrier over damaged tissues. It binds to proteins at the wound site, forming a protective layer that shields the area from external irritants and bacterial contamination. This barrier not only promotes faster healing but also enhances tissue regeneration by stimulating growth factors and improving blood supply to the injured surface.\n\nTinidazole, a potent antiprotozoal and antibacterial agent, further strengthens the formulation by targeting anaerobic bacteria and protozoa commonly responsible for wound infections. Its inclusion helps reduce microbial load, prevent secondary infections, and create an ideal environment for clean and complication-free healing.\n\nFinally, Povidone Iodine, a trusted antiseptic, provides broad-spectrum germicidal action against bacteria, fungi, viruses, and spores. It effectively reduces wound contamination, minimizes odor, and prevents colonization of harmful microorganisms. Together, these ingredients create a synergistic effect that supports comprehensive wound management.\n\nProduct Uses\n\nThis ointment is commonly prescribed for:\n\nDiabetic foot ulcers\nHelps control infection while promoting tissue repair in complex ulcers.\n\nPressure sores and bedsores\nProvides protection and healing acceleration for chronic wounds.\n\nBurns (first and second degree)\nPrevents infection and reduces healing time.\n\nMinor cuts, abrasions, and skin injuries\nIdeal for daily wound care and minor trauma.\n\nPost-surgical wounds\nHelps prevent infection and supports clean healing.\n\nInfected wounds or skin lesions\nEffective against wounds contaminated with anaerobic bacteria or other pathogens.\n\nGynecological wound care\nMay be used for episiotomy care or infected perineal wounds under medical supervision.\n\nKey Benefits\n1. Broad-Spectrum Antimicrobial Protection\n\nThe combination of Tinidazole and Povidone Iodine provides robust defense against bacteria, fungi, protozoa, and viruses, significantly reducing infection risk.\n\n2. Accelerated Healing and Tissue Regeneration\n\nSucralfate forms a protective layer that maintains moisture balance, promotes granulation tissue formation, and speeds up recovery.\n\n3. Reduced Inflammation and Discomfort\n\nBy minimizing bacterial load and shielding damaged tissues, the ointment helps reduce redness, swelling, and pain.\n\n4. Ideal for Complex and Chronic Wounds\n\nEspecially effective for ulcers, burns, and infected wounds where multiple layers of treatment are needed.\n\n5. Odor Control in Infected Wounds\n\nPovidone Iodine’s antimicrobial action helps reduce foul odor associated with infected or necrotic tissue.\n\n6. Safe and Well-Tolerated\n\nWhen used as directed, this combination ointment is suitable for a wide range of patients, including those with difficult-to-heal wounds.\n\nPossible Side Effects\n\nWhile generally safe, some individuals may experience:\n\nMild skin irritation or redness\n\nBurning or stinging sensation at the application site\n\nDryness or peeling of skin\n\nAllergic reactions (rare), such as rash or itching\n\nTemporary discoloration of skin due to Povidone Iodine\n\nSensitivity reactions in iodine-allergic individuals\n\nPatients with thyroid disorders, severe burns, or extensive wounds should use Povidone Iodine-containing products only under medical guidance.\n\nConclusion\n\nSucralfate, Tinidazole, and Povidone Iodine Ointment stands out as a highly effective and versatile wound-care solution. Its triple-action design—protective, antimicrobial, and regenerative—makes it ideal for managing complicated wounds, preventing infection, and supporting faster, cleaner healing. Whether used for chronic ulcers, burns, surgical wounds, or everyday skin injuries, this formulation offers a reliable and scientifically supported approach to comprehensive wound management. With its blend of protection, infection control, and healing enhancement, it remains a valuable tool for both healthcare professionals and patients seeking superior wound-care outcomes.", "price": 98.0, "discountamount": 29.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2214, "imageuri": "https://productimages.withfloats.com/actual/691f0bfde83a250c0e084bb9.png", "tileimageuri": "https://productimages.withfloats.com/tile/691f0bfde83a250c0e084bb9.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-20T12:39:23.314Z", "updatedon": "2026-03-26T05:41:50.903Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//sucralfate-tinidazole-and-povidone-iodine-ointment/2214", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Steris Healthcare Pvt. Ltd", "category": "GENERAL RANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69142bf71d499513a92e5772", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Nicorandil Tablets 5mg", "description": "Nicorandil Tablets 5 mg is a vasodilatory anti-anginal medication widely prescribed for the management and prevention of angina pectoris (chest pain) associated with coronary artery disease (CAD). Angina results from an imbalance between the heart’s oxygen demand and supply due to restricted blood flow in the coronary arteries. Nicorandil offers a dual mechanism of action — acting both as a nitrate-like vasodilator and a potassium channel opener, making it unique among anti-anginal agents.\n\nBy improving oxygen delivery to the myocardium and reducing cardiac workload, Nicorandil 5 mg Tablets provide effective relief from anginal pain and reduce the frequency and severity of ischemic episodes. It is also beneficial in preventing future attacks, improving exercise tolerance, and enhancing the overall quality of life in patients with chronic stable angina.\n\nComposition\n\nEach tablet contains:\n\nNicorandil IP – 5 mg\n\nExcipients – q.s.\n\nNicorandil tablets are available in film-coated form to ensure stability, easy swallowing, and optimal absorption. They are manufactured in compliance with Good Manufacturing Practices (GMP) standards to ensure safety, purity, and efficacy.\n\nPharmacological Action / Mechanism of Action\n\nNicorandil exhibits a dual mechanism that makes it distinct among anti-anginal drugs:\n\nNitrate-Like Effect:\nNicorandil acts as a nitric oxide (NO) donor. Nitric oxide activates guanylate cyclase, increasing cyclic GMP (cGMP) levels in vascular smooth muscle. This leads to relaxation of blood vessels, particularly veins and large arteries, thereby reducing preload and afterload on the heart. This nitrate-like activity lowers myocardial oxygen demand.\n\nPotassium Channel Opening Effect:\nNicorandil opens ATP-sensitive potassium (KATP) channels in vascular smooth muscle, resulting in arteriolar vasodilation. This increases coronary blood flow and improves oxygen supply to ischemic heart tissues.\n\nTogether, these effects reduce cardiac workload, enhance coronary perfusion, and prevent anginal pain by correcting the oxygen supply-demand mismatch in the heart muscle.\n\nUses and Indications\n\nNicorandil Tablets 5 mg are indicated for the treatment and prevention of angina pectoris in adults, particularly:\n\nChronic Stable Angina:\n\nHelps reduce the frequency and severity of chest pain associated with exertion or emotional stress.\n\nProphylaxis of Angina Attacks:\n\nUsed regularly to prevent anginal episodes, especially in patients with known coronary artery disease.\n\nAdjunct Therapy in Ischemic Heart Disease (IHD):\n\nCan be used alongside beta-blockers, calcium channel blockers, or antiplatelet drugs for enhanced symptom control and long-term protection.\n\nImprovement of Exercise Tolerance:\n\nReduces the likelihood of anginal pain during physical activity, enabling patients to perform daily tasks comfortably.\n\nIn some clinical cases, Nicorandil is also considered for post-myocardial infarction recovery, as it improves coronary perfusion, although this is at the discretion of a cardiologist.\n\nDosage and Administration\n\nRecommended Starting Dose: 5 mg to 10 mg twice daily.\n\nMaintenance Dose: May be increased gradually to 10–20 mg twice daily, depending on clinical response and tolerance.\n\nThe tablets should be swallowed whole with water, preferably at the same times each day.\n\nNicorandil should not be stopped abruptly; dosage tapering is recommended to avoid rebound angina.\n\nAlways follow the dosage instructions provided by the physician.\n\nKey Benefits\n\nDual Mechanism for Comprehensive Relief:\nCombines nitrate-like and potassium channel-opening properties for both arterial and venous dilation, providing superior protection against anginal attacks.\n\nImproves Coronary Blood Flow:\nDilates coronary arteries, increasing oxygen delivery to ischemic myocardial tissues.\n\nReduces Cardiac Workload:\nBy decreasing preload (venous return) and afterload (arterial resistance), Nicorandil minimizes the heart’s oxygen consumption.\n\nRapid Onset of Action:\nNicorandil acts within a short duration, offering quick relief from anginal discomfort.\n\nPrevents Future Angina Episodes:\nRegular use helps maintain steady control of chest pain, improving exercise capacity and quality of life.\n\nCompatible with Other Cardiac Medications:\nCan be safely used alongside antiplatelet agents, beta-blockers, ACE inhibitors, and statins as part of comprehensive cardiac care.\n\nFavorable Safety Profile:\nCompared to nitrates, Nicorandil carries a lower risk of tolerance development, making it suitable for long-term therapy.\n\nEnhances Myocardial Protection:\nNicorandil’s KATP channel activation provides additional cardioprotective effects by improving microvascular blood flow and limiting ischemic damage during stress.\n\nPrecautions and Warnings\n\nAlthough Nicorandil is generally well-tolerated, certain precautions are advised:\n\nHypotension:\nNicorandil may cause a drop in blood pressure due to vasodilation. Caution is advised in patients with hypotension or dehydration.\n\nConcurrent Use with Nitrates:\nShould not be used together with other nitrate medications to avoid severe hypotension.\n\nOral or Gastrointestinal Ulcers:\nRarely, Nicorandil may cause ulcerations in the mouth, intestines, or skin. Treatment should be discontinued if ulceration occurs.\n\nPatients with Low Blood Volume:\nUse cautiously in individuals with hypovolemia or those on diuretics.\n\nDriving and Machinery:\nDizziness or light-headedness may occur; avoid driving until effects are known.\n\nPregnancy and Lactation:\nShould be used only if prescribed by a physician when the potential benefits outweigh the risks.\n\nPossible Side Effects\n\nNicorandil is generally safe but may cause some side effects, particularly at the start of therapy or with higher doses. Common and rare adverse reactions include:\n\nCommon Side Effects:\n\nHeadache (due to vasodilation)\n\nFlushing or warmth sensation\n\nDizziness or light-headedness\n\nNausea or mild stomach upset\n\nFatigue or weakness\n\nLess Common / Rare Side Effects:\n\nHypotension (low blood pressure)\n\nPalpitations or tachycardia\n\nMouth ulcers, anal ulcers, or skin ulceration (uncommon but serious — discontinue if occurs)\n\nRash or allergic reaction\n\nVisual disturbances (rare and usually reversible)\n\nIf any severe reaction or persistent discomfort occurs, medical attention should be sought promptly.\n\nDrug Interactions\n\nAvoid concomitant use with nitrates or phosphodiesterase type-5 inhibitors (e.g., Sildenafil, Tadalafil), as it may cause a dangerous fall in blood pressure.\n\nCaution with antihypertensive drugs or diuretics, which may enhance hypotensive effects.\n\nAlcohol consumption can potentiate dizziness or hypotension and should be limited.\n\nStorage and Handling\n\nStore below 30°C, protected from moisture and direct sunlight.\n\nKeep out of reach of children.\n\nDo not use tablets past the expiry date or if the packaging is damaged.\n\nConclusion\n\nNicorandil Tablets 5 mg offer a modern and effective approach to managing angina pectoris, providing reliable relief through their dual-action mechanism. By combining nitrate-like vasodilation with potassium channel opening, Nicorandil ensures both oxygen supply improvement and reduction of cardiac workload — the cornerstone of angina management.\n\nIt is well-tolerated, fast-acting, and suitable for long-term therapy, making it a preferred choice for patients with chronic stable angina. Regular use under medical supervision helps reduce the frequency of chest pain, improve physical endurance, and enhance the overall quality of life in individuals with coronary artery disease.", "price": 381.0, "discountamount": 115.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2202, "imageuri": "https://productimages.withfloats.com/actual/69142c03b53db80943abd33d.png", "tileimageuri": "https://productimages.withfloats.com/tile/69142c03b53db80943abd33d.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-12T06:40:55.795Z", "updatedon": "2026-03-16T08:18:00.245Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//nicorandil-tablets-5mg/2202", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MAYORANDIL 5 ", "category": "CARDIOLOGYRANGE", "tags": [ "nicorandil tablets 5mg", "nicorandil 5 mg tablets uses", "nicorandil tablet 5mg benefits", "nicorandil 5mg medicine", "nicorandil tablets ip 5 mg", "what is nicorandil 5mg used for", "how does nicorandil tablet work", "nicorandil 5mg mechanism of action", "nicorandil tablets for angina treatment", "nicorandil tablet uses in heart disease", "nicorandil 5mg tablet price in india", "buy nicorandil 5mg tablets online", "nicorandil 5mg tablet brands", "nicorandil tablets manufacturer", "nicorandil tablets wholesale supplier" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false } ], "hasmoreitems": false, "isapirequest": false, "totalresults": 27, "query": null, "floatingpoint": null }

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