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{ "products": [ { "_id": "6957b1f01063d98b1e8f2f17", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Opipramol Dihydrochloride 100 mg", "description": "OPIRAPROL 100, featuring Opipramol Dihydrochloride 100 mg, stands out as a reliable medication from Steris Healthcare Pvt Ltd designed to address anxiety disorders and related somatic issues. This tricyclic compound offers targeted relief by modulating brain chemicals for better emotional balance. Patients often find it helps restore daily functionality without the heavier sedation of some alternatives.\n​\n\nProduct Overview\nOPIRAPROL 100 contains 100 mg of Opipramol Dihydrochloride per tablet, a dibenzazepine derivative primarily classified as an anxiolytic with antidepressant properties. Manufactured by Steris Healthcare Pvt Ltd, it targets generalized anxiety disorder (GAD) and somatoform disorders, where physical symptoms like unexplained pain or fatigue stem from psychological stress. Unlike typical antidepressants that focus solely on serotonin reuptake, Opipramol acts as a sigma-1 receptor agonist, influencing calcium signaling and neurotransmitter release for a calming effect.\n​\n\nThe formulation ensures steady absorption, making it suitable for adults needing moderate to higher dosing. Each pack typically includes 10 tablets, priced accessibly for ongoing therapy under medical supervision. Steris emphasizes quality with WHO-GMP certification, positioning OPIRAPROL 100 as a trusted option in India's mental health market.\n​\n\nHow It Works\nOpipramol Dihydrochloride in OPIRAPROL 100 primarily binds to sigma receptors in the brain, promoting translocation to cell membranes and enhancing neurotransmitter modulation, especially serotonin and dopamine. This biphasic action first reduces acute tension and insomnia, then stabilizes mood over time by downregulating sigma-2 sites during chronic use.\n​\n\nIt also exhibits mild antihistamine and anticholinergic effects, contributing to its sedative properties without strong reuptake inhibition like classic tricyclics. By calming overactive neural pathways, it alleviates the cycle of worry and physical unease, allowing clearer thinking and restful sleep. Clinical studies highlight its efficacy in somatoform cases, where patients fixate on bodily sensations amplified by anxiety.\n​\n\nKey Uses\nHealthcare providers prescribe OPIRAPROL 100 for several interconnected conditions rooted in anxiety.\n\nGeneralized anxiety disorder, easing excessive worry, restlessness, and irritability that disrupt work and relationships.\n​\n\nSomatoform disturbances target fatigue, pain, or gastrointestinal issues without clear organic cause.\n​\n\nMild depressive episodes with prominent anxiety, supporting mood without full antidepressant escalation.\n​\n\nAdjunctive therapy for sleep bruxism or insomnia linked to stress, based on emerging evidence.\n​\n\nIn practice, it suits patients in high-stress environments, like urban professionals in Jaipur facing daily pressures, helping them regain focus and productivity.\n​\n\nKey Benefits\nUsers of OPIRAPROL 100 report transformative effects that extend beyond symptom relief.\n\nRapid anxiety reduction promotes mental clarity, enabling better concentration and decision-making in daily tasks.\n​\n\nMood stabilization balances emotional swings, fostering stronger interpersonal connections and resilience.\n​\n\nEnhanced sleep quality combats insomnia, leading to refreshed mornings and sustained energy.\n​\n\nImproved daily functioning boosts productivity, which is vital for professionals balancing career and personal life.\n​\n\nLower sedation profile compared to benzodiazepines allows safe use during daytime hours.\n​\n\nLong-term, it enhances quality of life by breaking anxiety cycles, with many patients noting fewer somatic complaints after consistent use.\n​\n\nDosage Guidelines\nTake OPIRAPROL 100 as directed, typically 100 mg once or twice daily for adults, swallowed whole with water, with or without food. Start low to assess tolerance, adjusting up to 300 mg daily for severe cases under supervision.\n​\n\nFor children over 6, dosing follows 3 mg/kg body weight, but adult use predominates. Maintain consistent timing to stabilize blood levels, and taper gradually to avoid withdrawal. Missed doses should resume normally without doubling.\n\nPotential Side Effects\nMost side effects of OPIRAPROL 100 are mild and diminish with time, but monitoring remains essential.\n\nCommon ones (1-10%) include dry mouth, nasal congestion, fatigue, dizziness, and orthostatic hypotension, often resolving as the body adjusts.\n\nOccasional (0.1-1%) effects encompass constipation, weight gain, tremor, blurred vision, tachycardia, and mild liver enzyme elevation.\nRare issues (<0.1%) like allergic rashes, urinary retention, confusion, or leukopenia require immediate medical attention, especially in elderly patients or those with heart conditions.\n​\nPrecautions\nAvoid OPIRAPROL 100 in acute glaucoma, urinary retention, ileus, or uncontrolled epilepsy due to anticholinergic risks.\n​\nPregnant or lactating women need doctor approval, as safety data limits use. Steer clear of alcohol and CNS depressants to prevent amplified drowsiness.\n\nMonitor heart rhythm in bradycardia patients and liver function during prolonged therapy. Abrupt stops can trigger rebound anxiety.\nWhen to Consult a Doctor\nSeek prompt advice if side effects intensify, mood worsens paradoxically, or new symptoms like chest pain emerge. Regular check-ins ensure optimal dosing, particularly for those on interacting meds like MAOIs.\n​\nConclusion\nOPIRAPROL 100 with Opipramol Dihydrochloride 100 mg delivers effective, balanced relief for anxiety and somatic disorders, empowering users toward calmer, more productive lives. Backed by Steris Healthcare's commitment to quality, it bridges the gap between symptom management and holistic well-being when used responsibly. Always prioritize professional guidance to maximize benefits while minimizing risks.\n", "price": 154.0, "discountamount": 46.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2259, "imageuri": "https://productimages.withfloats.com/actual/6957b22c6b1ead52de1e2df4.png", "tileimageuri": "https://productimages.withfloats.com/tile/6957b22c6b1ead52de1e2df4.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-02T11:54:24.869Z", "updatedon": "2026-03-13T07:53:58.661Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/opipramol-dihydrochloride-100-mg/2259", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "OPIRAPROL 100", "category": "NEUROLOGYRANGE", "tags": [ "opipramol dihydrochloride.", "opipramol dihydrochloride tablets uses.", "opipramol dihydrochloride tablets uses in hindi.", "opipramol dihydrochloride tablets.", "opipramol dihydrochloride uses.", "opipramol dihydrochloride side effects", "opipramol dihydrochloride tablet.", "what is opipramol dihydrochloride.", "side effects of opipramol dihydrochloride.", "opipramol dihydrochloride dosage.", "opipramol dihydrochloride tablet for anxiety disorder", "medicine for generalized anxiety disorder treatment", "tablet for anxiety and stress management", "medication for nervous tension and anxiety", "how opipramol dihydrochloride works for anxiety", "opipramol vs amitriptyline for anxiety", "medicines for stress and anxiety relief", "opipramol dihydrochloride tablets supplier india" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6662e74687f0960e14a2d95a", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Gefitinib 250mg", "description": "\n\nGEFISTERIS 250 is a premium pharmaceutical formulation containing Gefitinib 250mg, a breakthrough targeted therapy medication manufactured by Steris Healthcare. This innovative oral medication represents a significant advancement in the treatment of non-small cell lung cancer (NSCLC), offering patients a precise, scientifically-designed approach to combating one of the world's most challenging malignancies. GEFISTERIS 250 is specifically engineered to target the underlying molecular mechanisms that drive certain types of lung cancer, providing hope and extended survival for patients who carry specific genetic mutations.\nAs a tyrosine kinase inhibitor, GEFISTERIS 250 works at the cellular level to interrupt the signals that tell cancer cells to grow and divide. This targeted approach differs fundamentally from traditional chemotherapy, which affects both healthy and cancerous cells. By focusing specifically on cancer cells with epidermal growth factor receptor (EGFR) mutations, GEFISTERIS 250 offers a more refined treatment strategy with potentially fewer systemic side effects and improved quality of life during treatment.\nUnderstanding Gefitinib 250mg: The Science Behind GEFISTERIS 250\nGefitinib 250mg, the active pharmaceutical ingredient in GEFISTERIS 250, belongs to a revolutionary class of medications known as epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs). The development of this medication marked a paradigm shift in oncology, moving from one-size-fits-all chemotherapy approaches to personalized, mutation-specific treatments.\nThe EGFR protein is found on the surface of cells and plays a crucial role in cell growth and division. In normal cells, EGFR activation is carefully regulated. However, in certain lung cancers, mutations in the EGFR gene cause the receptor to remain constantly active, sending continuous signals for the cell to grow, divide, and survive—leading to uncontrolled cancer growth. GEFISTERIS 250 works by blocking the tyrosine kinase activity of the mutated EGFR protein, effectively turning off the growth signal and causing cancer cells to stop proliferating and eventually die.\nThis precision targeting is what makes GEFISTERIS 250 particularly effective for patients whose tumors harbor activating EGFR mutations, particularly the common exon 19 deletions or exon 21 L858R substitution mutations. Before initiating treatment with GEFISTERIS 250, patients undergo molecular testing to confirm the presence of these mutations, ensuring that the therapy is appropriately matched to their specific cancer biology.\nPrimary Uses and Indications of GEFISTERIS 250\nGEFISTERIS 250 is primarily indicated for the treatment of adult patients with metastatic non-small cell lung cancer whose tumors have specific EGFR mutations. The medication is approved for both first-line treatment in newly diagnosed patients and for those whose disease has progressed after platinum-based chemotherapy.\nFirst-Line Treatment: When EGFR mutations are detected in treatment-naïve patients, GEFISTERIS 250 offers an excellent first-line option, often providing superior progression-free survival compared to traditional chemotherapy regimens. Patients starting with targeted therapy typically experience better tolerability and quality of life during initial treatment phases.\nSecond-Line and Beyond: For patients whose cancer has progressed after chemotherapy, GEFISTERIS 250 provides an effective alternative treatment option, particularly when EGFR mutation testing was not performed initially or when the mutation status was unknown at the time of first treatment.\nThe medication is taken orally as a once-daily tablet, offering significant convenience compared to intravenous chemotherapy that requires hospital visits and lengthy infusion times. This oral administration allows patients to maintain greater independence and normalcy in their daily lives while receiving effective cancer treatment.\nKey Benefits of GEFISTERIS 250\n1. Targeted Cancer Fighting Action\nThe primary benefit of GEFISTERIS 250 lies in its precision targeting mechanism. Unlike conventional chemotherapy that attacks all rapidly dividing cells in the body, GEFISTERIS 250 specifically targets cancer cells bearing EGFR mutations. This selective action means that healthy cells are largely spared, resulting in a more favorable side effect profile and better preservation of normal bodily functions during treatment.\n2. Superior Efficacy in EGFR-Mutant NSCLC\nClinical trials have consistently demonstrated that GEFISTERIS 250 and other EGFR-TKIs provide superior progression-free survival compared to chemotherapy in patients with EGFR-mutant NSCLC. Response rates typically range from 60-80% in appropriate patient populations, with many patients experiencing significant tumor shrinkage and symptomatic improvement within weeks of starting treatment.\n3. Improved Quality of Life\nPatients taking GEFISTERIS 250 often report better quality of life compared to those receiving traditional chemotherapy. The medication's targeted nature results in fewer debilitating side effects such as severe nausea, hair loss, and profound fatigue. Many patients can continue working, traveling, and engaging in normal daily activities while on treatment.\n4. Convenient Oral Administration\nGEFISTERIS 250's once-daily oral dosing eliminates the need for frequent hospital visits for intravenous chemotherapy infusions. Patients take one tablet daily at home, providing tremendous convenience and reducing the burden of treatment. This ease of administration contributes significantly to treatment adherence and patient satisfaction.\n5. Rapid Symptom Relief\nMany patients experience rapid improvement in cancer-related symptoms such as cough, shortness of breath, chest pain, and fatigue within the first few weeks of GEFISTERIS 250 treatment. This quick symptomatic relief can dramatically improve quality of life even before significant tumor shrinkage is visible on imaging studies.\n6. Extended Survival Benefits\nLong-term data demonstrates that appropriate use of EGFR-TKIs like GEFISTERIS 250 contributes to extended overall survival in patients with EGFR-mutant lung cancer. When used as part of a comprehensive treatment strategy, including potential sequential therapies after progression, patients can achieve survival times that were unimaginable before the advent of targeted therapies.\n7. Manageable Side Effect Profile\nWhile GEFISTERIS 250 does cause side effects, they are generally more manageable than those associated with traditional chemotherapy. Most side effects can be effectively controlled with supportive medications, dose modifications, or temporary treatment interruptions, allowing patients to continue benefiting from therapy.\n8. Quality Manufacturing by Steris Healthcare\nGEFISTERIS 250 benefits from Steris Healthcare's commitment to pharmaceutical excellence. Each tablet undergoes rigorous quality testing to ensure consistent potency, purity, and bioavailability. This quality assurance means patients receive reliable, effective medication with every dose.\nSide Effects of GEFISTERIS 250 (Gefitinib 250mg)\nWhile GEFISTERIS 250 offers significant therapeutic benefits, patients should be aware of potential side effects. Understanding these effects enables early recognition and appropriate management.\nCommon Side Effects (Affecting 20% or More of Patients):\nSkin Reactions: The most characteristic side effect of GEFISTERIS 250 is an acne-like rash, typically appearing on the face, chest, and back within the first few weeks of treatment. This rash, while cosmetically concerning for some patients, actually correlates with better treatment response. The rash can be managed with topical antibiotics, moisturizers, and sun protection. In severe cases, temporary dose reduction may be necessary.\nDiarrhea: Approximately 50-60% of patients experience diarrhea of varying severity. Mild diarrhea can often be managed with dietary modifications and over-the-counter anti-diarrheal medications like loperamide. Patients should stay well-hydrated and contact their healthcare provider if diarrhea becomes severe or persistent, as dose adjustments may be needed.\nNail Changes: Some patients develop paronychia (nail bed inflammation) or other nail abnormalities. Proper nail care, avoiding trauma to the nail beds, and wearing protective gloves during housework can help minimize these effects.\nDry Skin: Many patients experience skin dryness and itching. Regular use of fragrance-free moisturizers, gentle cleansers, and avoidance of hot showers can help manage these symptoms.\nMouth Sores: Oral mucositis or stomatitis can develop in some patients. Good oral hygiene, avoiding spicy or acidic foods, and using alcohol-free mouthwashes can provide relief.\nLess Common but Serious Side Effects:\nInterstitial Lung Disease (ILD): While rare (1-2% of patients), ILD is the most serious potential side effect of GEFISTERIS 250. Symptoms include sudden onset or worsening of respiratory symptoms such as difficulty breathing, cough, or fever. This requires immediate medical attention and usually necessitates permanent discontinuation of the medication.\nLiver Function Abnormalities: Elevated liver enzymes can occur, requiring regular monitoring through blood tests. Most cases are asymptomatic and reversible with dose modification or temporary discontinuation.\nEye Problems: Dry eyes, corneal erosion, or other ocular issues may develop. Regular use of lubricating eye drops and ophthalmological evaluation when symptoms occur can prevent serious complications.\nGastrointestinal Perforation: Though rare, serious gastrointestinal complications including perforation can occur, particularly in patients with underlying GI conditions.\nManagement Strategies:\nMost side effects can be effectively managed through:\n\nProactive supportive care and prophylactic measures\nDose modifications (reduction to 250mg every other day in some cases)\nTemporary treatment interruptions allowing recovery\nSymptomatic treatment with appropriate medications\nPatient education about early recognition and reporting of symptoms\n\nPatients should maintain open communication with their healthcare team, reporting any new or worsening symptoms promptly. Regular monitoring through clinical visits and laboratory testing helps identify and address side effects before they become serious.\nDosage and Administration Guidelines\nThe standard dose of GEFISTERIS 250 is one 250mg tablet taken orally once daily, with or without food. The tablet should be swallowed whole with water and should not be crushed or chewed. If a dose is missed and it's been less than 12 hours since the scheduled time, patients should take the missed dose. If more than 12 hours have passed, skip the missed dose and resume the regular schedule—never double up on doses.\nTreatment continues until disease progression or unacceptable toxicity occurs. Some patients remain on GEFISTERIS 250 for months or even years if they continue to benefit without prohibitive side effects. Dose modifications may be necessary based on individual tolerance, typically reducing the frequency to every other day rather than lowering the individual dose.\nPrecautions and Important Considerations\nPatients taking GEFISTERIS 250 should be aware of several important precautions. The medication can cause harm to developing fetuses, so women of childbearing potential must use effective contraception during treatment and for at least two weeks after the last dose. Breastfeeding should be avoided during treatment and for two weeks after completion.\nGEFISTERIS 250 can interact with medications that affect stomach acid, including proton pump inhibitors and H2-receptor antagonists. If antacids are needed, they should be taken several hours apart from GEFISTERIS 250. The medication may also interact with certain other drugs metabolized by the liver, so patients should inform their healthcare provider about all medications, supplements, and herbal products they're taking.\nRegular monitoring is essential during GEFISTERIS 250 treatment, including periodic liver function tests, pulmonary symptom assessment, and clinical evaluation for skin and other toxicities. Patients should avoid prolonged sun exposure and use high-SPF sunscreen, as the medication can increase photosensitivity.\nConclusion\nGEFISTERIS 250 represents a transformative treatment option for patients with EGFR-mutant non-small cell lung cancer, offering targeted, effective therapy with a manageable side effect profile. Manufactured by Steris Healthcare with unwavering commitment to quality and patient outcomes, GEFISTERIS 250 delivers Gefitinib 250mg in a formulation designed for optimal bioavailability and consistent therapeutic effect.\nThe medication's precision targeting of cancer-driving mutations, combined with convenient oral administration and generally tolerable side effects, makes GEFISTERIS 250 an excellent choice for eligible patients. While side effects do occur and require monitoring and management, the potential benefits—including tumor response, symptom improvement, extended progression-free survival, and enhanced quality of life—often significantly outweigh the risks for appropriately selected patients.\nSuccess with GEFISTERIS 250 requires partnership between patients and their healthcare teams. Molecular testing to confirm EGFR mutation status before treatment, adherence to the prescribed regimen, proactive management of side effects, and regular monitoring all contribute to optimal outcomes. For many patients with EGFR-mutant lung cancer, GEFISTERIS 250 offers not just treatment, but genuine hope for extended, quality life.\nAs personalized medicine continues to evolve, medications like GEFISTERIS 250 exemplify the power of matching treatments to individual tumor characteristics. Steris Healthcare's commitment to delivering this advanced therapy with assured quality and accessibility ensures that more patients can benefit from the remarkable advances in targeted cancer treatment that Gefitinib 250mg represents.\n", "price": 2760.0, "discountamount": 828.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "food", "Call", "Uses", "Rash", "Note", "NSCLC", "Email", "nausea", "Dosage", "spread", "WhatsApp", "diarrhea", "Gefitinib", "treatment", "One tablet", "GEFISTERIS", "information", "sterispharma", "consultation", "sterisonline", "Side Effects", "cancer cells", "targeted therapy", "Regular monitoring", "healthcare provider", "small cell lung cancer", "healthcare professional", "specific EGFR mutations", "epidermal growth factor receptor", "potential liver function alterations" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1530, "imageuri": "https://productimages.withfloats.com/actual/667d25ffb56721898510e93e.png", "tileimageuri": "https://productimages.withfloats.com/tile/667d25ffb56721898510e93e.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-07T10:56:06.808Z", "updatedon": "2026-04-15T10:04:00.767Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//gefitinib-250mg/1530", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "GEFISTERIS 250", "category": "Oncology", "tags": [ "gefitinib 250 mg uses", "gefitinib 250 mg online purchase", "gefitinib 250 mg tablets price in india", "non-small cell lung cancer (NSCLC).", "triggered by chemotherapy.", "cancer biology.", "Superior Efficacy in EGFR-Mutant NSCLC", "gefitinib 250mg", "gefitinib 250mg tablet", "gefitinib 250mg tab", "gefitinib 250 mg tablet uses in lung cancer", "gefitinib tablets 250 mg dosage and benefits", "gefitinib 250 mg price in india", "gefitinib 250 mg EGFR inhibitor for NSCLC treatment india" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6662e4df2bed1f08484d7249", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Enzalutamide 160 mg Tablet", "description": "ENZULAMIDE 160\nEnzalutamide 160mg capsules represent a breakthrough in targeted therapy for advanced prostate cancer, specifically designed to inhibit androgen receptor signaling at multiple levels, slowing cancer progression even in castration-resistant cases. This oral medication, typically taken as a single daily 160mg dose (four 40mg capsules), binds directly to the androgen receptor, preventing nuclear translocation and DNA binding, which starves hormone-dependent prostate tumors of growth signals. Patients with metastatic castration-resistant prostate cancer (mCRPC), non-metastatic CRPC (nmCRPC), or metastatic castration-sensitive prostate cancer (mCSPC) benefit from its ability to delay disease advancement, reduce PSA levels, and extend progression-free survival.​\n\nAdministered continuously without cycling, enzalutamide 160mg maintains steady-state plasma levels for consistent anti-tumor activity, making it suitable for long-term management alongside standard care. Its role expands beyond initial hormone therapy failures, offering hope where traditional options falter.​\n\nProduct Uses: Targeting Advanced Prostate Cancer\nEnzalutamide 160mg primarily treats metastatic castration-resistant prostate cancer (mCRPC) post-chemotherapy or in pre-chemo settings, where tumors grow despite low testosterone. It excels in non-metastatic CRPC (nmCRPC) by delaying metastasis onset, with trials showing median metastasis-free survival exceeding 3 years versus placebo. In mCSPC, combination with ADT prolongs overall survival by months, reducing radiographic progression risks.​\n\nClinicians prescribe it for high-risk patients with rising PSA despite androgen deprivation therapy (ADT), as it shrinks tumors, alleviates bone pain from metastases, and improves quality of life metrics like urinary function and fatigue scores. Regular monitoring via PSA doubling time and imaging guides ongoing use.​\n\nKey Benefits of Enzalutamide 160mg\nEnzalutamide 160mg delivers transformative outcomes through potent androgen blockade:\n\nExtended Progression-Free Survival: PROSPER trial data indicate 97% risk reduction in metastasis or death for nmCRPC; ENZAMET shows 33% overall survival benefit in mCSPC.​\n\nPSA Response Rates: Over 78% achieve ≥50% PSA decline in mCRPC, correlating with radiographic stability and symptom palliation.​\n\nBone Metastasis Control: Lowers skeletal-related events by 30-40%, preserving mobility and reducing fracture incidence when paired with bone agents.​\n\nQuality of Life Preservation: FACT-P scores improve in pain, appetite, and emotional well-being domains, enabling patients to maintain daily activities longer.​\n\nOral Convenience: Once-daily dosing without food restrictions enhances adherence compared to infusions or multi-pill regimens.​\n\nThese advantages position enzalutamide 160mg as a cornerstone in modern prostate cancer protocols, particularly for fit patients tolerating its profile.​\n\nSide Effects: Managing Risks Effectively\nWhile effective, enzalutamide 160mg carries side effects from androgen suppression and receptor antagonism, affecting 70-90% of users to varying degrees. Most prove manageable with supportive care, dose holds, or adjustments, but vigilance remains essential.​\n\nCommon Side Effects\nFrequently reported (≥10%) issues include:\n\nFatigue/Asthenia (30-40%): Profound tiredness impacting daily tasks; rest, exercise, and stimulants like modafinil help.​\n\nHot Flashes (20-25%): Sudden heat waves; cooling strategies and SSRIs alleviate symptoms.​\n\nMusculoskeletal Pain (15-30%): Joint/muscle aches; NSAIDs or physical therapy provide relief.​\n\nDiarrhea/Constipation (10-20%): Alternating bowel changes; fiber, hydration, and laxatives balance gut function.​\n\nHypertension (10-15%): Blood pressure elevations; routine monitoring and antihypertensives control spikes.​\n\nThese transient effects often peak in first months, diminishing with acclimation.​\n\nSerious Side Effects\nSeek immediate care for:\n\nSeizures (1-2%): Risk higher with brain history; anticonvulsants or discontinuation advised.​\n\nFalls/Fractures (10-15%): Due to weakness, dizziness; fall precautions and bone density scans mitigate.​\n\nCardiovascular Events: Myocardial infarction, strokes (2-5%); lipid/BP checks essential.​\n\nPosterior Reversible Encephalopathy Syndrome (PRES): Rare confusion, seizures, vision loss; MRI confirms.​\n\nSevere Skin Reactions: Stevens-Johnson syndrome; rash monitoring critical.​\n\nBaseline neurological assessments and quarterly labs optimize safety.​\n\nDosage and Administration Guidelines\nSwallow four 40mg capsules whole once daily at the same time, with or without food, totaling 160mg. No dose reductions below 120mg recommended; hold for grade 3-4 toxicity, resuming at prior dose once resolved. Hepatic impairment (Child-Pugh B/C) warrants caution; renal adjustments unnecessary. Continue indefinitely unless progression or intolerance occurs.​\n\nPrecautions and Monitoring\nAvoid in seizure history without prophylaxis; women (especially pregnant) must not handle due to teratogenicity. Strong CYP2A4 inducers/inhibitors alter exposure—adjust accordingly. Elderly patients face amplified fall risks; annual DEXA scans track bone health. Regular PSA, testosterone, CBC, liver enzymes, and ECGs ensure proactive management.​\n\nConclusion\nEnzalutamide 160mg stands as a pivotal advancement in prostate cancer care, offering substantial delays in disease progression, symptom control, and survival gains for patients facing hormone-resistant stages. By meticulously balancing its robust benefits against manageable side effects through vigilant monitoring and supportive measures, individuals regain control over their health journey. Consult oncologists to integrate this therapy seamlessly, tailoring it to personal profiles for optimal, life-extending results\nEmail: info@sterispharma.com / contact@sterispharma.com\nCall/WhatsApp: 7877551268, 7849827488\n\n\n\n\n\n\n\n", "price": 5531.0, "discountamount": 1660.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "Call", "Email", "mCRPC", "growth", "doctor", "Dosage", "action", "fatigue", "product", "WhatsApp", "patients", "androgens", "ENZULAMIDE", "hot flashes", "information", "Enzalutamide", "sterisonline", "sterispharma", "cancer cells", "hypertension", "male hormones", "administration", "health condition", "Common side effects", "comprehensive advice", "healthcare professional", "potent anti-androgen medication", "metastatic castration-resistant prostate cancer" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1528, "imageuri": "https://productimages.withfloats.com/actual/667d2980c303c6d6ad1360bf.png", "tileimageuri": "https://productimages.withfloats.com/tile/667d2980c303c6d6ad1360bf.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-07T10:45:51.202Z", "updatedon": "2026-03-12T07:58:25.307Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//enzalutamide-160-mg-tablet/1528", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "ENZULAMIDE 160", "category": "Oncology", "tags": [ "enzalutamide 160 mg price in india", "enzalutamide 160 mg uses", "", "enzalutamide 160 mg side effects", "prostate cancer", "prostate tumors of growth signals", "metastatic castration-resistant prostate cancer", "enzalutamide 160 mg tablet uses", "enzalutamide 160 mg tablet dosage", "enzalutamide 160 mg tablet price in india", "enzalutamide 160 mg tablet composition", "enzalutamide 160 mg tablet benefits", "enzalutamide 160 mg tablet side effects", "enzalutamide 160 mg tablet how it works", "enzalutamide 160 mg tablet mechanism of action", "enzalutamide tablets 160 mg information", "enzalutamide 160 mg tablet cost", "enzalutamide 160 mg tablet supplier india", "enzalutamide 160 mg tablet manufacturer", "enzalutamide 160 mg tablet wholesale price", "enzalutamide 160 mg tablet availability in india", "what is enzalutamide 160 mg tablet", "enzalutamide 160 mg tablet treatment use", "enzalutamide 160 mg tablet precautions", "enzalutamide 160 mg tablet alternatives", "enzalutamide 160 mg tablet substitute", "enzalutamide 160 mg tablet india", "enzalutamide 160 mg tablet near me", "enzalutamide 160 mg tablet online india" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6662e3b87247ae19c482b97c", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Enzalutamide 40mg", "description": "Enzalutamide 40 mg capsules represent a breakthrough in targeted therapy for advanced prostate cancer, particularly in metastatic castration-resistant prostate cancer (mCRPC) and metastatic castration-sensitive prostate cancer (mCSPC). This second-generation androgen receptor inhibitor works by disrupting multiple steps in the androgen signaling pathway, offering patients a chance to slow disease progression, reduce tumor burden, and extend survival even after other treatments fail. Administered as a once-daily oral capsule, enzalutamide 40 mg provides four capsules per day (total 160 mg), making it convenient for long-term use in clinical settings where hormone therapy alone proves insufficient.​\n\nPatients often turn to enzalutamide when facing rising PSA levels despite androgen deprivation therapy (ADT), experiencing bone pain, or dealing with cancer spread to lymph nodes or distant sites. Its high affinity for androgen receptors—5-8 times stronger than first-generation antiandrogens like bicalutamide—ensures potent blockade without agonist activity, translating to real-world benefits like delayed chemotherapy needs and improved quality of life during treatment.​\n\nProduct Use and Indications\nEnzalutamide 40 mg primarily treats metastatic castration-resistant prostate cancer (mCRPC) in patients previously treated with docetaxel or progressing despite ADT. The FDA and EMA approvals extend to non-metastatic CRPC (nmCRPC) with high-risk biochemical recurrence and metastatic castration-sensitive prostate cancer (mCSPC) alongside ADT, based on landmark trials like AFFIRM, PREVAIL, PROSPER, and ARCHES.​\n\nKey uses include:\n\nSlowing tumor growth in hormone-refractory stages by inhibiting androgen-driven proliferation.\n\nReducing skeletal-related events like fractures or spinal cord compression in bone metastases.\n\nDelaying progression to chemotherapy in pre-chemotherapy mCRPC, with PREVAIL showing 17-month median radiographic progression-free survival (rPFS) versus 4 months for placebo.​\n\nIn mCSPC, ARCHES trial data demonstrated 61% risk reduction in progression or death when combined with ADT. Clinicians monitor PSA response (≥50% decline in 70-80% of patients) and imaging every 3 months to assess efficacy.​\n\nMechanism of Action\nEnzalutamide 40 mg exerts a threefold blockade on androgen receptor (AR) signaling: it competitively inhibits androgen binding to AR (with affinity rivaling dihydrotestosterone), prevents nuclear translocation of the ligand-receptor complex, and disrupts DNA binding and coactivator recruitment at androgen response elements. This comprehensive inhibition downregulates oncogenes like TMPRSS2-ERG fusion genes common in prostate cancer, inducing apoptosis and halting cell proliferation without lowering systemic testosterone levels.​\n\nUnlike earlier antiandrogens, enzalutamide avoids partial agonist effects, ensuring pure antagonism even in AR-overexpressing tumors. Its active metabolite, N-desmethyl enzalutamide (via CYP2C8), contributes 30% to activity, with steady-state levels achieved in 4 weeks.​\n\nKey Benefits\nExtended Progression-Free Survival: In PREVAIL (pre-chemo mCRPC), median overall survival reached 32.4 months versus 30.2 for placebo; PROSPER (nmCRPC) delayed metastasis by 22 months.​\n\nPSA Response and Tumor Shrinkage: 78% PSA90 response rate; radiographic responses in 29% with measurable disease.​\n\nQuality of Life Preservation: Delays pain progression (hazard ratio 0.40) and chemotherapy (by 17 months), maintaining daily function.​\n\nBone Protection: Reduces fractures by 30% in high-risk patients via AR inhibition in osteoblasts.​\n\nCombination Synergy: Enhances ADT efficacy in mCSPC, cutting death risk by 33% per ARCHES.​\n\nThese benefits position enzalutamide 40 mg as a cornerstone in modern prostate cancer protocols, especially for fit patients tolerating oral therapy.​\n\nSide Effects\nEnzalutamide 40 mg carries a manageable profile, with most effects dose-related and reversible upon discontinuation.\n\nCommon Side Effects\nFatigue/Asthenia (34-50%): Often mild, peaking in first months; rest and nutrition help.\n\nArthralgia/Myalgia (14-21%): Joint/muscle pain managed with NSAIDs.\n\nHot Flashes (20%): Androgen blockade mimic; hydration aids.\n\nHeadache/Dizziness (12-19%): Transient; avoid driving if severe.\n\nHypertension (6-13%): Monitor BP monthly; antihypertensives as needed.\n\nGI Issues (diarrhea 12%, nausea 11%): Antiemetics support compliance.​\n\nSerious Side Effects\nSeizures (0.9%): Highest risk in epileptics or brain mets; EEG baseline, avoid triggers.\n\nPosterior Reversible Encephalopathy (PRES): Rare (<0.1%); headache, confusion—MRI confirms.\n\nFalls/Fractures (15% increased risk): Due to weakness/falls; DEXA scans recommended.\n\nCardiac Events (2-5%): MI/arrhythmias; ECG monitoring in CVD history.\n\nHepatic Injury (1%): ALT/AST elevation; monthly labs first 3 months.​\n\nDiscontinuation occurs in 8-10%; supportive care mitigates most.​\n\nDosage and Administration\nStandard dose: 160 mg (four 40 mg capsules) once daily, with or without food. Swallow intact; no crushing. Adjust for CYP2A4 inducers (e.g., rifampin—increase to 240 mg) or strong inhibitors (reduce to 80 mg). Continue until progression/toxicity; no dose interruptions beyond 28 days without reassessment.​\n\nPrecautions and Monitoring\nContraindicated in pregnancy (teratogenic; absolute contraception for men/ partners). Screen for seizure history; CYP2C8/3A4 interactions (e.g., ketoconazole). Baseline LFTs, PSA, testosterone; imaging q8-12 weeks. Elderly (>75) monitor falls.​\nConclusion\nEnzalutamide 40 mg stands as a transformative therapy, empowering prostate cancer patients with prolonged control over aggressive disease through precise AR inhibition. Balancing robust efficacy—evidenced by landmark trials delaying metastasis and death—with proactive side effect management, it enhances survival and daily living. Patients achieve meaningful milestones, from family events to travel, underscoring its role in personalized oncology. Consult oncologists for integration into care plans, ensuring optimal outcomes in this challenging journey.\nEmail: info@sterispharma.com / contact@sterispharma.com\nCall/WhatsApp: 7877551268, 7849827488\n\n\n\n\n\n\n\n\n", "price": 10781.0, "discountamount": 3235.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "Call", "Email", "doctor", "product", "fatigue", "WhatsApp", "treatment", "schedules", "ENZULAMIDE", "monitoring", "hot flashes", "information", "sterisonline", "hypertension", "sterispharma", "prostate cancer", "Enzalutamide 40mg", "prescribed dosages", "androgen receptors", "cancer cell growth", "Common side effects", "comprehensive guidance" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1527, "imageuri": "https://productimages.withfloats.com/actual/667d2a356c582d228f45a098.png", "tileimageuri": "https://productimages.withfloats.com/tile/667d2a356c582d228f45a098.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-07T10:40:56.587Z", "updatedon": "2026-03-16T08:18:18.117Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//enzalutamide-40mg/1527", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "ENZULAMIDE 40", "category": "Oncology", "tags": [ "enzalutamide 40 mg side effects", "enzalutamide 40 mg brands in india", "enzalutamide 40 mg uses in hindi", "enzalutamide 40 mg dosage", "advanced prostate cancer", "prostate cancer", "metastatic castration-resistant prostate cancer", "enzalutamide 40mg tablets", "enzalutamide 40 mg capsule", "enzalutamide 40mg uses", "enzalutamide 40mg dosage", "enzalutamide 40mg price in india", "enzalutamide 40mg composition", "enzalutamide 40mg working mechanism", "enzalutamide 40mg side effects", "enzalutamide 40mg benefits", "enzalutamide 40mg drug information", "enzalutamide 40mg therapy details", "enzalutamide 40mg oral capsule", "enzalutamide 40mg treatment option", "enzalutamide 40mg pharmaceutical uses", "enzalutamide 40mg branded tablets", "enzalutamide 40mg generic medicine", "enzalutamide 40mg manufacturer in india", "what is enzalutamide 40mg used for", "how enzalutamide 40mg works", "is enzalutamide 40mg safe", "enzalutamide 40mg tablet information", "enzalutamide 40mg dosage guidelines" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6661a57d8da3a81d5c6a17dd", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Mycophenolate mofetil 500mg", "description": "MYCOPLASM M 500\nMycophenolate mofetil (500mg)\nMycoplasm M 500 is a medication containing Mycophenolate Mofetil in a 500mg dose. Mycophenolate Mofetil is an immunosuppressive drug used to prevent rejection in organ transplantation, particularly kidney, heart, and liver transplants. It works by inhibiting the proliferation of T and B lymphocytes, which are involved in the immune response that leads to rejection.\n\nThis medication is typically prescribed in combination with other immunosuppressants as part of a comprehensive transplant treatment regimen. It is important to take Mycoplasm M 500 exactly as prescribed by your healthcare provider to ensure optimal therapeutic outcomes and to minimize the risk of rejection or other complications.\n\nCommon side effects of Mycophenolate Mofetil may include gastrointestinal disturbances such as nausea, vomiting, diarrhea, and abdominal pain. It can also increase the risk of infections due to its immunosuppressive effects. Patients should be monitored regularly by their healthcare provider while taking this medication to assess for any potential adverse effects and to adjust the dosage as needed.\n\nMycoplasm M 500 should not be used in pregnant women or those planning to become pregnant without consulting a healthcare professional, as it can cause harm to the developing fetus. Additionally, it may interact with other medications, so it is important to inform your doctor about all the medications you are currently taking before starting Mycoplasm M 500 therapy.For further information:\nEmail: info@sterispharma.com / contact@sterispharma.com\nCall/WhatsApp: 7877551268, 7849827488\nORDER Now: \n\n\n\n\nMycophenolate mofetil 500 mg stands as a cornerstone in modern immunosuppressive therapy, primarily designed to prevent organ transplant rejection in kidney, heart, and liver recipients. As a prodrug, it rapidly converts to its active form, mycophenolic acid (MPA), which selectively targets the proliferation of T and B lymphocytes—key players in immune responses that can attack transplanted organs. This medication, available in convenient 500 mg tablets, offers reliable protection against acute rejection episodes, making it an essential component in post-transplant regimens worldwide.​\n\nProduct Uses\nMycophenolate mofetil 500 mg finds its primary application in solid organ transplantation, where it helps maintain long-term graft survival. For kidney transplant patients, it is typically administered alongside corticosteroids and calcineurin inhibitors like cyclosporine or tacrolimus to suppress the immune system's overreaction to the new organ. In heart and liver transplants, it plays a similar role, reducing the incidence of rejection by inhibiting antibody production and cell-mediated immunity.​\n\nBeyond transplants, healthcare providers increasingly use mycophenolate mofetil 500 mg for various autoimmune conditions. It effectively manages lupus nephritis by curbing inflammation in the kidneys, showing superior efficacy over traditional therapies in preserving renal function. Rheumatoid arthritis patients benefit from its ability to dampen joint inflammation, while those with dermatomyositis or scleroderma experience reduced skin and muscle involvement. Off-label, it treats inflammatory bowel diseases like Crohn's disease and even certain skin disorders such as pemphigus vulgaris, where immune-mediated blistering threatens quality of life.​\n\nKey Benefits\nThe therapeutic advantages of mycophenolate mofetil 500 mg extend far beyond basic immunosuppression, offering patients enhanced outcomes and improved daily living.\n\nSuperior Graft Protection: Clinical data highlight reduced acute rejection rates by up to 50% when combined with standard regimens, leading to better long-term organ function and survival.​\n\nSelective Lymphocyte Targeting: By depleting guanosine nucleotides in T and B cells via inosine monophosphate dehydrogenase (IMPDH) inhibition, it spares other cell types, minimizing broad toxicity seen with older immunosuppressants.​\n\nAnti-Inflammatory Effects: MPA inhibits adhesion molecule glycosylation, preventing lymphocyte recruitment to inflamed sites, which alleviates symptoms in autoimmune flares.​\n\nOral Convenience: The 500 mg formulation allows flexible dosing—typically 1 gram twice daily—without the need for injections, improving patient adherence.​\n\nVersatility Across Conditions: Proven efficacy in lupus, vasculitis, and myositis expands its utility, often allowing steroid dose reduction and fewer relapses.​\n\nCardiovascular and Anticancer Potential: Emerging evidence suggests it delays graft atherosclerosis by reducing lipid oxidation and may hinder tumor progression in certain malignancies due to its impact on nucleotide synthesis.​\n\nThese benefits translate to fewer hospital readmissions, better quality of life, and cost savings in long-term care for transplant and autoimmune patients.​\n\nSide Effects\nWhile mycophenolate mofetil 500 mg provides robust immunosuppression, it carries risks typical of this drug class, necessitating vigilant monitoring.\n\nCommon side effects affect the gastrointestinal tract most prominently, with nausea, vomiting, diarrhea, and abdominal pain occurring in over 30% of users. These often improve with dose adjustments or enteric-coated alternatives, but hydration and antiemetics help manage them effectively.​\n\nHematologic issues like leukopenia, anemia, and thrombocytopenia arise due to bone marrow suppression, requiring regular complete blood counts—weekly initially, then monthly. Infections pose a significant threat, as suppressed immunity increases susceptibility to viral (e.g., CMV), bacterial, and fungal pathogens; prophylactic antivirals are standard.​\n\nLess frequent but notable effects include hypertension, tremor, insomnia, and elevated liver enzymes. Women face heightened risks of congenital malformations if used during pregnancy, mandating effective contraception and pregnancy testing. Rare severe reactions encompass progressive multifocal leukoencephalopathy (PML) from JC virus reactivation and hypersensitivity syndromes.​\n\nDosage and Administration Notes\nStandard dosing for renal transplants involves 1 gram (two 500 mg tablets) twice daily, starting within 72 hours post-surgery, with adjustments for renal impairment. Hepatic transplant patients may require higher initial doses due to metabolism differences. Always take on an empty stomach with water to optimize absorption, avoiding antacids that bind MPA.​\n\nPrecautions and Interactions\nPatients must avoid live vaccines, report fevers promptly, and undergo TB screening pre-treatment. Drug interactions with azathioprine, cholestyramine, or rifampin can alter levels, so pharmacists review regimens closely. Regular monitoring of MPA blood levels ensures therapeutic efficacy without toxicity.​\n\nConclusion\nMycophenolate mofetil 500 mg emerges as a transformative immunosuppressive agent, safeguarding transplanted organs and taming autoimmune storms with its precise mechanism of lymphocyte suppression and anti-inflammatory prowess. By delivering key benefits like reduced rejection, versatile applications, and manageable administration, it empowers patients to reclaim normalcy post-transplant or amid chronic illness. Despite potential side effects, proactive monitoring and personalized dosing mitigate risks, underscoring its value in contemporary medicine. For those navigating transplant recovery or autoimmune challenges, this medication offers hope and stability, backed by decades of clinical validation.\n\n", "price": 775.0, "discountamount": 256.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "part", "Call", "harm", "risk", "Email", "heart", "ORDER", "nausea", "kidney", "dosage", "doctor", "vomiting", "WhatsApp", "Patients", "diarrhea", "rejection", "infections", "500mg dose", "combination", "information", "sterisonline", "proliferation", "B lymphocytes", "abdominal pain", "pregnant women", "immune response", "developing fetus", "other medications", "liver transplants", "other complications", "healthcare provider", "Common side effects", "organ transplantation", "Mycophenolate mofetil", "immunosuppressive drug", "Mycoplasm M 500 therapy", "healthcare professional", "other immunosuppressants", "immunosuppressive effects", "potential adverse effects", "optimal therapeutic outcomes", "gastrointestinal disturbances", "comprehensive transplant treatment regimen" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1472, "imageuri": "https://productimages.withfloats.com/actual/6661a57fdd39d2ccddbc3bb9.jpg", "tileimageuri": "https://productimages.withfloats.com/tile/6661a57fdd39d2ccddbc3bb9.jpg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-06T12:03:09.216Z", "updatedon": "2026-03-12T08:00:39.14Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//mycophenolate-mofetil-500mg/1472", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MYCOPLASM M 500", "category": "NEPHROLOGYRANGE", "tags": [ "MYCOPLASM M 500", "Mycophenolate mofetil (500mg)", "Mycophenolate mofetil 500 mg tablet", "Mycophenolate mofetil 500 mg price", "Mycophenolate mofetil 500 mg dosage", "Mycophenolate mofetil uses", "Mycophenolate mofetil side effects", "mycophenolate mofetil 500mg tablet uses", "mycophenolate mofetil 500mg dosage for kidney transplant", "mycophenolate mofetil 500mg for autoimmune disease" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "662ba161f7fe09029cbf518e", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Temozolomide 100mg", "description": "TMOZOLMIDE 100\nTemodal 100mg Capsule stands as a cornerstone in oncology, specifically formulated with temozolomide 100mg to combat aggressive brain tumors like glioblastoma multiforme (GBM) and anaplastic astrocytoma. This oral alkylating agent crosses the blood-brain barrier effectively, delivering targeted chemotherapy that disrupts cancer cell DNA replication, halting tumor progression in adults with newly diagnosed or recurrent cases. Patients and caregivers often seek Temodal 100mg for its role in standard-of-care regimens, combining seamlessly with radiotherapy for enhanced survival outcomes in high-grade gliomas.​\n\nManufactured to rigorous standards, Temodal 100mg offers convenient capsule dosing, swallowed whole on an empty stomach to maximize bioavailability. Its proven track record in clinical settings makes it indispensable for neuro-oncology, where timely intervention can extend quality life years amid challenging diagnoses.​\n\nProduct Uses and Mechanism of Action\nTemodal 100mg Capsule primarily treats adult patients with newly diagnosed glioblastoma multiforme alongside radiotherapy, followed by maintenance monotherapy to prevent relapse. It also addresses refractory anaplastic astrocytoma—tumors that progress despite prior therapies—and recurrent malignant gliomas in children over three years, including brainstem glioma and high-grade astrocytoma.​\n\nThe mechanism hinges on temozolomide's rapid conversion to the active metabolite MTIC (5-(3-methyltriazen-1-yl)imidazole-4-carboxamide) at physiological pH, which methylates DNA at O6 and N7 guanine positions. This methylation induces DNA strand breaks during replication, triggering apoptosis in rapidly dividing glioma cells while sparing normal brain tissue to a degree. Unlike intravenous chemotherapies, Temodal 100mg achieves therapeutic CNS concentrations without specialized delivery, ideal for outpatient management.​\n\nIn practice, concomitant phase dosing (75 mg/m² daily with RT for 42 days) transitions to cycles of 150-200 mg/m² on days 1-5 every 28 days, tailored by body surface area and toxicity monitoring. This cyclical approach balances efficacy against cumulative myelosuppression, supporting long-term tumor control.​\n\nKey Benefits of Temodal 100mg Capsule\nTemodal 100mg delivers transformative benefits grounded in landmark trials:\n\nSuperior Survival in GBM: Concomitant temozolomide with RT extends median survival from 12.1 to 14.6 months, with 2-year survival rising from 10% to 26% per pivotal Phase III data.​\n\nMaintenance Therapy Efficacy: Post-RT cycles sustain progression-free survival up to 6-12 months in responders, delaying recurrence in MGMT-methylated tumors.​\n\nConvenient Oral Administration: Eliminates hospital visits, improving compliance for patients undergoing radiotherapy; rapid absorption (peak in 1 hour) ensures consistent exposure.​\n\nBlood-Brain Barrier Penetration: Achieves 30-40% cerebrospinal fluid levels, outperforming many alkylators in CNS malignancies.​\n\nPediatric Applicability: Effective in recurrent pediatric gliomas, with tolerance mirroring adults for ages 3+.​\n\nThese advantages position Temodal 100mg as a first-line essential, particularly for newly diagnosed cases where every month counts toward preserving cognitive function and independence.​\n\nReal-world use extends to off-label scenarios like metastatic melanoma or high-risk meningiomas under specialist oversight, though primary indications remain brain tumors. Its stability in acidic environments enhances reliability during storage and transit.​\n\nSide Effects of Temodal 100mg Capsule\nWhile Temodal 100mg offers life-prolonging potential, its myelotoxic profile demands vigilant hematologic monitoring. Common effects stem from DNA damage in rapidly proliferating bone marrow cells, peaking mid-cycle.​\n\nCommon Side Effects\nHematologic Toxicity: Neutropenia, thrombocytopenia (platelet nadir day 21-28), lymphopenia, and anemia affect 10-20%; febrile neutropenia occurs in vulnerable patients.​\n\nGastrointestinal Issues: Nausea (up to 50%), vomiting, constipation—mitigated by antiemetics like ondansetron taken 30 minutes prior.​\n\nNeurologic Symptoms: Fatigue, headache, ataxia, dizziness, or amnesia-like effects, often transient and RT-attributable.​\n\nOther: Alopecia, anorexia, rash, or elevated liver enzymes resolving post-cycle.​\n\nProphylactic measures like dose delays (if platelets <100 x 10⁹/L or neutrophils <1.5 x 10⁹/L) maintain tolerability; supportive care ensures most complete therapy.​\n\nSerious Side Effects\nRare but critical risks include:\n\nPancytopenia or Aplastic Anemia: Prolonged suppression risking infections or bleeding—mandatory weekly CBCs in early cycles.​\n\nSecondary Malignancies: Myeloid leukemia post-treatment (latency 1-5 years), hepatitis B reactivation.​\n\nOpportunistic Infections: Pneumocystis jirovecii pneumonia (PJP) prophylaxis with TMP-SMX recommended due to grade 3/4 lymphopenia.​\n\nNeurologic Deterioration: Status epilepticus, hemiplegia in advanced disease.​\n\nDiscontinue if non-hematologic CTC grade >2 persists; pregnant women face fetal toxicity—use contraception during and 6 months post-therapy.​\n\nDosage and Administration Guidelines\nInitiate Temodal 100mg at 75 mg/m² daily during RT (up to 49 days), escalating to 150 mg/m² (cycle 1) or 200 mg/m² (subsequent) for 5 days/23 off. Adjust downward for toxicity; hepatic/renal impairment rarely necessitates change unless severe. Capsules (5,20,100,250mg strengths) enable precise BSA-based dosing—e.g., ~100mg capsule for 70kg/m² patients.​\n\nPrecautions and Substitutes\nMonitor pregnancy status; avoid live vaccines. Substitutes include generic temozolomide capsules matching bioequivalence, though Temodal 100mg remains the reference standard. Interactions with valproic acid reduce clearance—increase dose 40% if co-administered.​\n\nConclusion\nTemodal 100mg Capsule empowers patients against glioblastoma's relentless advance, blending potent antineoplastic action with manageable administration for meaningful survival gains. From halting tumor growth via strategic DNA alkylation to fitting seamlessly into multimodal care, it embodies hope amid adversity—always under oncologist guidance to navigate toxicities and optimize outcomes. Embrace informed treatment; lives extend beyond statistics with vigilant care.\nFor further information:\nEmail: info@sterispharma.com / contact@sterispharma.com\nCall/WhatsApp: 7877551268, 7849827488\nBuy Now: \n", "price": 7400.0, "discountamount": 2220.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "part", "body", "types", "drugs", "class", "nausea", "spread", "growth", "surgery", "fatigue", "vomiting", "capsules", "TMOZOLMIDE", "instructions", "Temozolomide", "cancer cells", "brain tumors", "glioblastoma", "unusual symptoms", "potent medication", "other medications", "radiation therapy", "blood cell counts", "healthcare provider", "Common side effects", "comprehensive treatment plan" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 773, "imageuri": "https://productimages.withfloats.com/actual/662ba164481840e7a7fdadc0.png", "tileimageuri": "https://productimages.withfloats.com/tile/662ba164481840e7a7fdadc0.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-04-26T12:43:13.957Z", "updatedon": "2026-03-12T08:07:02.773Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//temozolomide-100mg/773", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "TMOZOLMIDE 100", "category": "NEPHROLOGYRANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6abe4471401ae1a1106d67d9", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Bisoprolol 1.25mg", "description": "Bisoprolol 1.25mg is the smallest tablet strength of bisoprolol, a heart-selective beta-1 blocker. Doctors usually prescribe it to start treatment or to build up the dose gradually in people with high blood pressure, chronic stable heart failure, or fast heart rhythms. It suits older adults, people with mild heart failure, and anyone who reacts strongly to beta-blockers. The medicine slows the heartbeat and eases the force of each contraction, so the heart works less hard. BISOGARD 1.25 from Steris Healthcare Pvt. Ltd. comes in a strip pack of 15 tablets. It is a Schedule H medicine, so it must only be started, changed, or stopped on a doctor's advice.\n\nProduct Snapshot\n\nBrand: BISOGARD 1.25\nManufacturer/Marketer: Steris Healthcare Pvt. Ltd., a WHO-GMP and ISO-certified pharmaceutical company in India\nActive ingredient: Bisoprolol Fumarate 1.25mg\nForm: Tablet\nPack size: 15 tablets\nDrug class: Cardioselective beta-1 blocker\nLegal status: Schedule H (valid prescription required)\nAvailability: Through Steris Healthcare's authorized pharmacies and its B2B PCD franchise network across India\nWhat Is Bisoprolol 1.25mg?\n\nIf your doctor has just prescribed bisoprolol 1.25mg, you have been given the lowest dose on purpose. Bisoprolol is a cardioselective beta-1 blocker, meaning it acts mostly on receptors in the heart and has much less effect on the lungs and blood vessels. This is a major reason it is preferred over older, non-selective beta-blockers, especially for people who also have a mild breathing problem.\n\nThe 1.25mg tablet is not a “light” medicine for mild illness. It is a carefully chosen entry point. In heart failure, a weakened heart can struggle if its rate or pressure drops too quickly, so cardiologists follow a “start low, go slow” approach. Treatment begins at 1.25mg, the response is watched for one to two weeks, and the dose is raised step by step (commonly 2.5mg, 3.75mg, 5mg, 7.5mg, and up to 10mg) as the heart adapts. That is why BISOGARD 1.25 is often the first tablet a newly diagnosed heart failure patient takes.\n\nWhat Is Bisoprolol 1.25mg Used For?\n\nDoctors commonly prescribe this strength for:\n\nChronic heart failure (HFrEF): as the first step of dose titration in patients with a reduced ejection fraction, alongside ACE inhibitors/ARBs and diuretics\nHigh blood pressure: especially in older adults, people with low body weight, and those who are sensitive to blood-pressure-lowering drugs\nStable angina: to reduce the heart's oxygen demand and relieve chest discomfort\nAfter a heart attack: in selected patients, under a cardiologist's care\nHeart rate control in some arrhythmias: sometimes used off-label at a low dose to gently bring down a fast heart rate\n\nAt 1.25mg, bisoprolol is seldom meant as the long-term sole treatment for high blood pressure in an otherwise healthy adult. It is usually the first rung of a titration ladder, or a steady maintenance dose for patients who are unusually beta-blocker sensitive (older age, low body weight, or borderline low pressure or pulse).\n\nHow Does Bisoprolol Work?\n\nBisoprolol selectively blocks beta-1 adrenergic receptors, which are packed mainly into heart muscle. This leads to several effects:\n\nSlower heart rate: the heart has more time to fill and rest between beats\nGentler contractions: the heart muscle needs less oxygen and energy\nLess renin from the kidneys: this helps blood pressure fall gradually over time\nLower overall cardiac workload: a real advantage for a heart that already struggles to pump well, as in heart failure\nKey Benefits of BISOGARD 1.25\nA gentle starting dose, well suited to careful titration in frail or elderly patients\nHeart-focused action, with less effect on the lungs and peripheral blood vessels than non-selective beta-blockers\nOnce-daily dosing, which makes it easier to stay on treatment\nA guideline-recommended beta-blocker for HFrEF with well-established outcomes data [Reviewer note: insert specific outcome statistics/trial citation pending medical sign-off]\nMade by Steris Healthcare Pvt. Ltd. under WHO-GMP and ISO-certified standards\nDosage Guidance\nUsual starting dose (heart failure): 1.25mg once a day, preferably in the morning\nDose increases: typically every 1–2 weeks (2.5mg, 3.75mg, 5mg, 7.5mg, up to a maximum of 10mg daily), depending on how well you tolerate it and on your pulse and blood pressure\nHigh blood pressure (sensitive patients): 1.25mg to 5mg once daily, as set by your doctor\nHow to take it: at the same time every day, with or without food, swallowed whole with water\nIf you miss a dose: take it when you remember, unless the next dose is almost due. Never take a double dose.\nNever stop suddenly: abrupt withdrawal can cause a rebound rise in heart rate, blood pressure, or chest pain. The dose must be reduced gradually under medical supervision.\nIs It Better to Take Bisoprolol in the Morning or at Night?\n\nMost doctors advise a morning dose. Bisoprolol lowers pulse and blood pressure, and taking it early matches its action to your daytime activity. A night-time dose could add to the body's natural overnight dip in blood pressure and raise the chance of dizziness when getting up in the dark. Some people who feel tired during the day are told by their doctor to switch to the evening. Do not change your dosing time without your doctor's approval.\n\nSide Effects of Bisoprolol 1.25mg\n\nCommon side effects\n\nTiredness or fatigue\nDizziness or light-headedness, especially on standing quickly\nCold hands or feet\nSlow pulse (bradycardia)\nHeadache\nMild stomach upset (nausea, loose stools)\nDisturbed sleep\n\nSerious side effects (get medical help promptly)\n\nVery slow heartbeat or fainting\nIncreasing breathlessness or swollen legs/ankles, which may mean heart failure is worsening\nAllergic reaction: rash, swelling of the face or throat, trouble breathing\nCold, numb, or bluish fingers and toes\nWheezing or new breathing difficulty, particularly in people with asthma or COPD\nMood changes, low mood, or confusion\nWhat Are the Bad Side Effects of Bisoprolol?\n\nThe effects that need urgent attention are a dangerously slow pulse, fainting, signs of worsening heart failure (swelling, breathlessness), severe allergic reactions, and airway tightening in people with lung disease. These are uncommon at the 1.25mg dose, but anyone who notices them should seek medical help right away. [Reviewer note: specific incidence rates pending clinical/medical sign-off]\n\nSubstitutes & Comparable Beta-Blockers\nMolecule\tSelectivity\tTypical Use Case\nBisoprolol\tHighly cardioselective\tHeart failure titration, hypertension\nMetoprolol Succinate ER\tCardioselective\tHypertension, angina, heart failure\nAtenolol\tCardioselective (older agent)\tHypertension\nCarvedilol\tNon-selective with alpha-blocking action\tHeart failure (adds vasodilation)\nPropranolol\tNon-selective\tMigraine prevention, anxiety-related fast heartbeat, essential tremor\nPrecautions & Who Should Avoid Bisoprolol\nNot suitable for people with severe bradycardia, certain forms of heart block (unless a pacemaker is fitted), unstable or acutely decompensated heart failure, or severe uncontrolled asthma\nUse carefully in diabetes, because beta-blockers can hide the warning signs of low blood sugar\nTake care in peripheral vascular disease, as cold extremities or leg pain on walking may worsen\nNever stop it abruptly; always taper under a doctor's guidance\nTell your doctor about every medicine you use, especially other blood-pressure drugs, calcium channel blockers, and certain antiarrhythmics\nIn pregnancy and breastfeeding, use only if your doctor advises it after weighing benefits and risks\nIs Bisoprolol Safe for Kidneys?\n\nThe body clears bisoprolol through both the liver and the kidneys in roughly equal measure. It is generally considered safe for people with normal or mildly reduced kidney function. When kidney impairment is significant, drug levels in the blood can rise, so your doctor may lower the dose or monitor you more closely. Always tell your prescriber about any kidney disease before starting.\n\nIs Bisoprolol a High-Risk Medication?\n\nBisoprolol is not a narrow therapeutic index drug like tacrolimus or warfarin, where small dose differences matter greatly. Even so, it needs supervised use because it directly affects heart rate and blood pressure. The main dangers are stopping it suddenly, which can set off rebound cardiac events, and using it with certain existing rhythm disorders. Taken as prescribed and checked regularly, it has a long and reassuring safety record.\n\nDoes 1.25mg Bisoprolol Lower Blood Pressure?\n\nYes. Even the smallest dose measurably reduces heart rate and blood pressure by lightening the heart's workload and reducing renin-driven narrowing of blood vessels. At this strength the effect on blood pressure is fairly mild, which is exactly why it is a safe place to begin, especially for older adults or people starting heart failure treatment. The dose is then raised gradually to reach full benefit.\n\nFrequently Asked Questions\n\n1. What is 1.25 mg of bisoprolol used for?\nMainly as a low starting dose when building up treatment for chronic heart failure, and for high blood pressure in people who are very sensitive to beta-blockers, such as older adults.\n\n2. What are the bad side effects of bisoprolol?\nThe more serious ones are a very slow pulse, fainting, worsening heart failure signs (swelling, breathlessness), severe allergy, and breathing trouble in people with lung conditions.\n\n3. What are the common side effects of bisoprolol fumarate 1.25 mg tablets?\nTiredness, dizziness, cold hands and feet, mild headache, and a slightly slower pulse.\n\n4. Is it better to take bisoprolol in the morning or at night?\nMorning is usually preferred so its effect fits daytime activity, though your doctor may suggest evenings in some cases.\n\n5. What is the cost of bisoprolol?\nPrice depends on strength, pack size, and brand. Use the “Check Price” option above for current BISOGARD 1.25 pricing from Steris Healthcare.\n\n6. Does 1.25 mg bisoprolol lower blood pressure?\nYes, though only modestly at this dose. The dose is often stepped up over time.\n\n7. Is bisoprolol safe for kidneys?\nGenerally yes for normal or mildly reduced kidney function. People with significant kidney impairment need dose adjustment and monitoring.\n\n8. Is bisoprolol a high-risk medication?\nIt is not a narrow therapeutic index drug, but it must never be stopped suddenly and should be used under medical supervision because of its direct effect on the heart.\n\n9. Can I take bisoprolol 1.25mg for the rest of my life?\nMany people with chronic heart failure or hypertension do take bisoprolol long term, but the dose usually rises as tolerated. Your doctor should review it regularly.\n\n10. What happens if I miss a dose of bisoprolol?\nTake it when you remember, unless the next dose is nearly due. In that case skip the missed one. Never take two together.\n\n11. Can bisoprolol 1.25mg cause weight gain?\nIt is not commonly reported at this dose. Fluid retention linked to heart failure itself should be reported to your doctor.\n\n12. Is bisoprolol safe for diabetic patients?\nIt can be used, with care, because beta-blockers may hide warning signs of low blood sugar such as a racing heartbeat.\n\n13. Can I stop taking bisoprolol suddenly if I feel fine?\nNo. Stopping abruptly can cause a rebound rise in heart rate, blood pressure, or chest pain. Reduce the dose gradually under medical guidance.\n\n14. Does bisoprolol interact with other blood pressure medicines?\nYes. Combining it with other drugs that lower heart rate or pressure (such as calcium channel blockers) can cause a very low pulse or pressure. Tell your doctor about all your medicines.\n\n15. Is BISOGARD 1.25 available without a prescription?\nNo. Bisoprolol is a Schedule H medicine in India and needs a valid prescription.\n\n16. How long does it take for bisoprolol 1.25mg to start working?\nSome effect on heart rate appears within hours, but the full benefit for blood pressure or heart failure symptoms builds over several weeks of regular use.\n\n17. Can pregnant women take bisoprolol?\nOnly if clearly necessary and prescribed by a doctor, as it may affect the baby's heart rate and growth.", "price": 39.0, "discountamount": 12.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2501, "imageuri": "https://productimages.withfloats.com/actual/6abe4474c205678e0b16a23a.png", "tileimageuri": "https://productimages.withfloats.com/tile/6abe4474c205678e0b16a23a.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-10-01T11:30:57.88Z", "updatedon": "2026-10-01T11:30:57.88Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//bisoprolol-1-25mg/2501", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Bisogard 1.25", "category": "CARDIOLOGYRANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6a9532d9dc13d720a47ea143", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Tolperisone Hydrochloride Sustained Release Tablets 450 mg", "description": "**Tolperisone hydrochloride** is a centrally acting muscle relaxant used to help reduce excessive muscle tone, stiffness, and muscle spasms associated with certain musculoskeletal and neurological conditions. Compared with some other centrally acting muscle relaxants, tolperisone is generally considered to have relatively limited sedative effects, although individual responses can vary.\n\n**TOPERITME 450** is formulated as a sustained-release tablet. This formulation is designed to release the active ingredient gradually, helping maintain its therapeutic effect over the prescribed dosing period.\n\nWhat TOPERITME 450 May Be Used For\n\nA healthcare professional may prescribe **TOPERITME 450** for conditions involving painful muscle tightness or spasms, including:\n\n* Painful muscle spasms\n* Selected musculoskeletal disorders\n* Neck and shoulder muscle stiffness\n* Lower back discomfort associated with muscle spasm\n* Cervical or lumbar spondylosis accompanied by muscle tightness\n* Muscle spasms associated with injury or trauma\n* Increased muscle tone associated with certain neurological conditions, when clinically appropriate\n\nThe decision to use tolperisone should be based on the patient's symptoms, diagnosis, and medical assessment.\n\nWhy TOPERITME 450 May Be Preferred\n\nTOPERITME 450 may offer several practical advantages when prescribed appropriately:\n\n* Sustained-release formulation for gradual drug delivery\n* Helps reduce muscle spasms and excessive muscle tension\n* May support improved movement when muscle stiffness is limiting mobility\n* Can help relieve discomfort associated with tight muscles\n* Convenient oral tablet formulation\n* Intended for use according to an individualized medical treatment plan\n\nPatients should always follow the dosage and duration recommended by their healthcare provider.\n\nMechanism of Action\n\n**Tolperisone hydrochloride** acts primarily through the central nervous system to reduce abnormal or excessive muscle activity. By modulating nerve signals involved in muscle tone and reflex activity, it can help decrease muscle stiffness and spasms.\n\nThe sustained-release formulation of **TOPERITME 450** is designed to release tolperisone progressively rather than all at once. This provides controlled delivery throughout the prescribed dosing interval.\n\n Dosage and Administration\n\nThe appropriate dose of **TOPERITME 450** should be determined by a qualified healthcare professional according to the patient's condition and treatment requirements.\n\nImportant administration instructions include:\n\n* Take the medicine exactly as prescribed.\n* Swallow the tablet whole with water.\n* Do not crush, chew, or split the sustained-release tablet unless specifically instructed by your doctor.\n* Maintain the prescribed dosing schedule.\n* If you forget a dose, seek guidance from your healthcare provider rather than taking an extra dose independently.\n\n Possible Side Effects\n\nSome individuals may experience side effects while taking **TOPERITME 450**. Potential reactions include:\n\n* Nausea\n* Dizziness\n* Headache\n* Weakness\n* Stomach discomfort\n* Allergic reactions\n\nNot everyone experiences side effects, and their severity can differ between individuals.\n\nIf serious allergic symptoms such as facial or throat swelling, breathing difficulty, or a severe unusual reaction occur, seek immediate medical attention.\n\nPrecautions to Discuss With Your Doctor\n\nBefore starting **TOPERITME 450**, inform your healthcare professional if you have:\n\n* Liver disease\n* Kidney disease\n* A previous history of drug allergies\n* Pregnancy or plans to become pregnant\n* Breastfeeding\n* Any other ongoing medical condition\n* Current use of prescription or over-the-counter medicines\n\nProviding a complete medication history can help your healthcare provider assess potential interactions and determine whether tolperisone is appropriate.\n\n Storage Guidelines\n\nFor proper storage of **TOPERITME 450**:\n\n* Keep the medicine in a cool and dry place.\n* Protect it from excessive moisture.\n* Keep the tablets away from direct sunlight.\n* Store according to the temperature instructions printed on the packaging.\n* Keep the medicine out of children's reach.\n* Do not use tablets after their stated expiry date.\n\nWhy Choose TOPERITME 450?\n\n**TOPERITME 450** contains tolperisone hydrochloride in a sustained-release formulation intended to provide controlled drug delivery. It may be selected by healthcare professionals for suitable patients experiencing muscle spasms, increased muscle tone, or stiffness associated with certain musculoskeletal conditions.\n\nTreatment should be individualized, and the medicine should be taken only according to professional medical advice.\n\n Frequently Asked Questions\n\nWhat is TOPERITME 450 prescribed for?\n\nTOPERITME 450 may be prescribed to help manage painful muscle spasms, stiffness, and increased muscle tone associated with selected musculoskeletal or neurological conditions.\n\nHow should I take TOPERITME 450?\n\nTake TOPERITME 450 exactly as prescribed and swallow the sustained-release tablet whole with water. Do not crush or chew it unless your healthcare professional specifically instructs you to do so.\n\nCan I stop TOPERITME 450 when my symptoms improve?\n\nDo not discontinue or modify your treatment without consulting your healthcare provider. The recommended treatment duration depends on your condition and individual response.\n\nIs TOPERITME 450 safe during pregnancy?\n\nUse during pregnancy should only be considered after consultation with a qualified healthcare professional, who can assess the potential benefits and risks for the individual patient.\n\nCan TOPERITME 450 cause drowsiness?\n\nSome individuals may experience dizziness or drowsiness, while others may not. If you experience impaired alertness, avoid driving or operating machinery until you know how the medicine affects you.", "price": 530.0, "discountamount": 159.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2500, "imageuri": "https://productimages.withfloats.com/actual/6a9532dd5c122cfb47f3b8bb.png", "tileimageuri": "https://productimages.withfloats.com/tile/6a9532dd5c122cfb47f3b8bb.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-08-31T07:52:57.389Z", "updatedon": "2026-08-31T07:52:57.389Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//tolperisone-hydrochloride-sustained-release-tablets-450-mg/2500", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "TOPERITIME 450", "category": "ORTHOPEDICS RANGE", "tags": [ "Tolperisone Hydrochloride Sustained Release Tablets 450 mg", "tolperisone hydrochloride uses", "tolperisone hydrochloride", "tolperisone hydrochloride use" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6a952f8fed078617ad2e762a", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Palmitoylethanolamide,Parsley Extract & Multivitamin Tablets", "description": "What Are Palmitoylethanolamide, Parsley Extract & Multivitamin Tablets?\n\nPalmitoylethanolamide, Parsley Extract & Multivitamin Tablets are a combination of nutritional supplements formulated with **palmitoylethanolamide (PEA), parsley extract, vitamins, and minerals**. The precise ingredients and quantities can differ between products, so the product label should always be checked for the exact composition and recommended serving.\n\nEach component has a different nutritional or biological role. **Palmitoylethanolamide (PEA)** is a naturally occurring fatty-acid amide that has been researched for its potential contribution to pain-related and inflammatory processes. Clinical research has shown particular interest in PEA for pain-management outcomes, especially when specific formulations such as micronized or ultramicronized PEA are used.\n\n**Parsley extract**, obtained from *Petroselinum crispum*, contains naturally occurring plant compounds, including flavonoids and phenolic constituents. Research has identified compounds such as apigenin and apiin in parsley and has demonstrated antioxidant activity in experimental settings. However, laboratory antioxidant activity should not be interpreted as proof that parsley extract prevents or treats a particular disease.\n\nThe multivitamin component supplies selected vitamins and minerals that contribute to normal nutritional requirements. Such supplements can be useful when dietary intake does not provide adequate amounts of particular nutrients, but they are intended to complement rather than replace a balanced diet.\n\nHow Do Palmitoylethanolamide, Parsley Extract & Multivitamin Tablets Work?\n\nThe combination works through the individual characteristics of its principal ingredients rather than through a single mechanism.\n\n1. Palmitoylethanolamide\n\nPalmitoylethanolamide (PEA) is an endogenous lipid compound found naturally in the body. It has been investigated for its potential analgesic, anti-inflammatory, and neuroprotective activities.\n\nClinical research has examined PEA in various pain-related and neurological settings. Evidence from randomized controlled trials has been particularly promising for pain-related outcomes. However, different PEA products can contain different formulations, and results from one preparation should not automatically be applied to every PEA supplement.\n\n 2. Parsley Extract\n\nParsley contains several naturally occurring phytochemicals, including flavonoids and phenolic compounds. These substances have demonstrated antioxidant properties in experimental research.\n\nThe presence of parsley extract therefore adds a plant-derived nutritional component to the formulation. However, human evidence remains more limited than laboratory research, so claims about disease prevention or treatment should be avoided unless supported by appropriate clinical evidence.\n\n3. Vitamins and Minerals\n\nThe multivitamin portion is designed to provide selected micronutrients that contribute to normal body functions. Vitamins and minerals participate in numerous physiological processes, including energy metabolism, immune function, nervous-system function, and maintenance of tissues.\n\nThe actual nutritional contribution depends on which vitamins and minerals are included and their quantities per tablet or serving.\n\nPotential Benefits of Palmitoylethanolamide, Parsley Extract & Multivitamin Tablets\n\nThe potential benefits of this combination depend on its exact formulation and the nutritional requirements of the individual.\n\nSupport for Pain-Management Strategies\n\nPEA is the component in this combination with the most relevant clinical research. Studies have evaluated PEA as a complementary nutritional approach in different pain conditions, with evidence showing particular interest in pain-related outcomes.\n\nHowever, the presence of PEA does not mean that every PEA-containing supplement is clinically proven to treat chronic pain, neuropathy, or other medical disorders.\n\nNutritional Support\n\nThe vitamin and mineral component can help increase nutrient intake when normal dietary consumption is inadequate.\n\nPeople with restricted diets, reduced food intake, or specific nutritional gaps may sometimes benefit from supplementation. However, supplements are not intended to replace a varied and nutritionally balanced diet.\n\nAntioxidant Nutritional Support\n\nParsley provides naturally occurring flavonoids and phenolic compounds that demonstrate antioxidant activity in experimental research.\n\nThese properties make parsley an interesting botanical ingredient in nutritional formulations, although laboratory findings do not necessarily establish a specific clinical benefit in humans.\n\nConvenient Combination Formula\n\nA combination tablet can offer convenience by bringing PEA, parsley extract, vitamins, and minerals together in one formulation.\n\nConsumers should focus on the actual quantities provided per tablet rather than simply the number of ingredients listed on the packaging.\n\nPalmitoylethanolamide, Parsley Extract & Multivitamin Tablets: Uses\n\nDepending on the specific product formulation and labeling, these tablets may be used as a nutritional supplement to\n\n* Support daily nutritional intake\n* Provide selected vitamins and minerals\n* Supply palmitoylethanolamide as part of a complementary wellness or pain-management approach\n* Provide naturally occurring compounds from parsley extract\n* Complement overall nutritional and antioxidant intake\n\nThese supplements should not be promoted as guaranteed treatments or cures for neuropathy, arthritis, inflammation, nerve injury, or other medical diseases.\n\n How to Select the Right Product\n\n 1. Check the PEA Quantity\n\nReview the label to determine the actual amount of **palmitoylethanolamide per tablet or daily serving**.\n\n 2. Consider the PEA Formulation\n\nDifferent clinical studies have evaluated different PEA preparations. Micronized, ultramicronized, and water-dispersible forms have received particular attention in clinical research.\n\n3. Review the Vitamin and Mineral Profile\n\nExamine the complete nutritional panel rather than assuming all multivitamin formulations contain the same nutrients and quantities.\n\n4. Avoid Nutrient Duplication\n\nIf you already use a multivitamin or individual supplements containing nutrients such as vitamin A, iron, zinc, or other minerals, compare the total daily intake to avoid unnecessary excess.\n\n 5. Check Product Information\n\nLook for transparent labeling, manufacturer details, batch information, expiry information, and appropriate quality-control details.\n\n 6. Choose According to Individual Requirements\n\nA product containing more ingredients or higher quantities is not necessarily more beneficial. Selection should be based on individual nutritional requirements and professional guidance when necessary.\n\nPossible Side Effects and Safety\n\nDietary supplements are generally well tolerated when appropriately formulated and used according to directions, but adverse effects and interactions can occur.\n\nPossible problems may include:\n\n* Nausea\n* Stomach discomfort\n* Changes in bowel habits\n* Headache\n* Sensitivity or allergic reactions to individual ingredients\n* Excessive intake of particular vitamins or minerals\n\nThe exact safety profile depends on the complete ingredient list and quantities in the individual product.\n\nPeople who take prescription medicines, have significant medical conditions, are pregnant or breastfeeding, or are preparing for surgery should discuss supplementation with a qualified healthcare professional.\n\nWho Should Use Extra Caution?\n\nAdditional care may be appropriate for individuals who:\n\n* Take several nutritional supplements\n* Regularly use prescription medicines\n* Have an existing medical condition\n* Are pregnant or breastfeeding\n* Have an allergy or sensitivity to an ingredient\n* Are preparing for surgery\n* Are considering supplementation for persistent or unexplained pain\n\nMultivitamins should also not be used as a substitute for a consistently varied diet.\n\nFrequently Asked Questions\n\n1. What are Palmitoylethanolamide, Parsley Extract & Multivitamin Tablets used for?\n\nThey are combination nutritional supplements containing PEA, parsley extract, vitamins, and minerals. Depending on the formulation, they may provide nutritional support and PEA as a complementary component of a wellness or pain-management approach.\n\n2. What are the main benefits of these tablets?\n\nPotential benefits depend on the formulation. PEA has been clinically studied mainly for pain-related outcomes; parsley provides naturally occurring plant compounds; and vitamins and minerals help support nutritional intake when dietary consumption is insufficient.\n\n3. Can Palmitoylethanolamide help with nerve pain?\n\nPEA has been investigated in several pain-related and neurological conditions, with clinical research showing promising findings for some pain outcomes. However, it should not automatically be considered a proven treatment for every type of nerve pain or neuropathy.\n\n4. Are Palmitoylethanolamide, Parsley Extract & Multivitamin Tablets safe?\n\nSafety depends on the ingredients, quantities, individual health status, and medicines being used. Most appropriately used basic nutritional supplements are tolerated by many people, but excessive nutrient intake and interactions can occur.\n\n5. What side effects can these tablets cause?\n\nPotential effects can include stomach discomfort, nausea, bowel changes, headache, or sensitivity to an ingredient. The exact side effects depend on the complete formulation.\n\n6. Can these tablets be taken with another multivitamin?\n\nCombining multivitamins should be approached carefully because overlapping ingredients can result in excessive intake of certain vitamins or minerals. Compare both labels before combining supplements.\n\n7. How should I choose palmitoylethanolamide tablets?\n\nCheck the PEA quantity, formulation, parsley extract amount, complete vitamin and mineral profile, serving instructions, manufacturer information, and product quality details.\n\n8. Can these tablets replace prescribed pain medicines?\n\nNo. A nutritional supplement should not automatically replace prescribed medication or professional medical care. Persistent, severe, worsening, or unexplained pain should be evaluated appropriately.\n\n9. Do multivitamins provide long-term health benefits?\n\nMultivitamins can increase nutrient intake when dietary intake is inadequate, but this does not mean they universally prevent chronic diseases or extend lifespan in healthy individuals.\n\n10. Can I take these tablets every day?\n\nFollow the dosage or serving instructions provided for the specific product. Taking more than the recommended amount does not necessarily provide greater benefits and may increase the risk of excessive nutrient intake.\n\nConclusion\n\nPalmitoylethanolamide, Parsley Extract & Multivitamin Tablets** combine **PEA, parsley extract, vitamins, and minerals** into a single nutritional formulation. PEA is the component with the most relevant clinical research, particularly in relation to pain-related outcomes, while parsley contributes naturally occurring botanical compounds and the multivitamin component supports dietary micronutrient intake.\n\nThe benefits and appropriate use of the combination depend on the exact formulation, ingredient quantities, and individual nutritional requirements. Therefore, consumers should review the complete product label and use the supplement according to its recommended directions.", "price": 579.0, "discountamount": 170.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2499, "imageuri": "https://productimages.withfloats.com/actual/6a952f923833cb5247c5da2d.png", "tileimageuri": "https://productimages.withfloats.com/tile/6a952f923833cb5247c5da2d.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-08-31T07:38:55.369Z", "updatedon": "2026-08-31T07:38:55.369Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//palmitoylethanolamide-parsley-extract-multivitamin-tablets/2499", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "PALMI URIDIN 600", "category": "NEUROLOGY RANGE", "tags": [ "Palmitoylethanolamide,Parsley Extract & Multivitamin Tablets", "palmitoylethanolamide", "multivitamin tablets", "best multivitamin tablets", "multivitamin tablets uses" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false } ], "hasmoreitems": false, "isapirequest": false, "totalresults": 27, "query": null, "floatingpoint": null }