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"name": "Glimepiride IP1 mg, Voglibose IP 0.2 MG & Metformin Hydrochloride IP 500 mg ",
"description": "GLIMITERIS MV1 0.2 is an advanced fixed-dose combination (FDC) medication designed for adults with Type 2 Diabetes Mellitus (T2DM) who require more than lifestyle modifications or single/dual therapy to maintain optimal blood sugar levels. This innovative formulation brings together the power of three well-established antidiabetic agents—Glimepiride (1 mg), Voglibose (0.2 mg), and Metformin Hydrochloride SR (500 mg)—to provide comprehensive glycemic control.\n\nIt is particularly effective for patients struggling with postprandial hyperglycemia, fasting glucose regulation, and HbA1c reduction, making it a preferred choice in cases of poorly controlled diabetes.\n\n \n\nMechanism of Action\nThe therapeutic benefit of GLIMITERIS MV1 0.2 comes from the unique synergy of its three components, each targeting different aspects of glucose metabolism:\n\n1. Glimepiride (1 mg) – Sulfonylurea\nStimulates insulin secretion by activating pancreatic beta cells.\n\nProvides a long-lasting effect with comparatively lower hypoglycemia risk than older sulfonylureas.\n\nHelps reduce both fasting and postprandial glucose levels.\n\n2. Voglibose (0.2 mg) – Alpha-Glucosidase Inhibitor\nDelays the breakdown and absorption of carbohydrates in the intestine.\n\nMinimizes post-meal glucose spikes (PPBG).\n\nActs locally in the gut and has minimal systemic absorption, which reduces systemic side effects.\n\n3. Metformin Hydrochloride SR (500 mg) – Biguanide\nDecreases hepatic glucose production (gluconeogenesis).\n\nImproves peripheral insulin sensitivity, enhancing glucose uptake in muscles.\n\nDoes not cause hypoglycemia on its own.\n\nThe sustained-release (SR) formulation ensures extended control and reduces gastrointestinal side effects.\n\n \n\nIndications\nGLIMITERIS MV1 0.2 is indicated for:\n\nAdults with Type 2 Diabetes Mellitus.\n\nPatients inadequately controlled with monotherapy or dual therapy.\n\nManagement of fasting and postprandial hyperglycemia.\n\nLong-term HbA1c reduction as part of a comprehensive diabetes care plan.\n\n \n\nKey Benefits\n✅ Comprehensive Blood Sugar Control – Acts on fasting, post-meal, and long-term HbA1c levels.\n✅ Postprandial Spike Management – Voglibose effectively controls carbohydrate-induced sugar surges.\n✅ Reduced Pill Burden – Combines three medicines into a single tablet.\n✅ Lower Hypoglycemia Risk – Metformin and Voglibose balance out Glimepiride’s insulin-secreting effect.\n✅ Weight Management Support – Metformin may promote modest weight loss or prevent weight gain.\n✅ Improved Tolerability – SR formulation of Metformin enhances gastrointestinal comfort.\n\n \n\nDosage and Administration\nRecommended dose: One tablet once or twice daily with meals, or as directed by the physician.\n\nAdministration tips:\n\nTake with the first bite of a main meal to maximize Voglibose’s effect.\n\nSwallow whole with water; do not crush or chew the SR tablet.\n\nDose adjustments: Based on blood sugar monitoring, clinical response, and renal/hepatic function.\n\n \n\nContraindications\nGLIMITERIS MV1 0.2 is not suitable for patients with:\n\nType 1 diabetes or diabetic ketoacidosis.\n\nSevere renal impairment (eGFR <30 mL/min/1.73 m²).\n\nHepatic dysfunction.\n\nSevere gastrointestinal diseases.\n\nHistory of lactic acidosis.\n\nHypersensitivity to Glimepiride, Voglibose, or Metformin.\n\nPregnancy and lactation (unless strictly advised by a physician).\n\n \n\nWarnings and Precautions\nHypoglycemia: Risk is higher when combined with other antidiabetics or with missed meals.\n\nLactic Acidosis: A rare but life-threatening effect of Metformin—renal function monitoring is essential.\n\nGI Side Effects: Voglibose and Metformin may cause bloating, flatulence, or diarrhea (usually temporary).\n\nVitamin B12 Monitoring: Long-term Metformin use may reduce B12 absorption.\n\nLiver and Kidney Function: Regular monitoring is recommended for safe long-term use.\n\n \n\nAdverse Effects\nCommon:\nGlimepiride: Mild hypoglycemia, dizziness, slight weight gain.\n\nVoglibose: Gas, abdominal discomfort, mild diarrhea.\n\nMetformin SR: Nausea, bloating, metallic taste, loose stools.\n\nRare but Serious:\nLactic acidosis (from Metformin).\n\nSevere hypoglycemia (especially if meals are skipped).\n\nAllergic reactions such as rash, itching, or swelling.\n\nElevated liver enzymes.\n\nSeek medical attention if symptoms such as rapid breathing, confusion, severe fatigue, or muscle pain occur.\n\n \n\nDrug Interactions\nIncreased hypoglycemia risk: With insulin, beta-blockers, and sulfonylureas.\n\nReduced Metformin efficacy: With corticosteroids, estrogens, and diuretics.\n\nLactic acidosis risk: Higher with alcohol or iodinated contrast agents. ",
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"description": "KATARINA DUSTING POWDER is a high-quality antifungal formulation designed to offer rapid relief from common skin fungal infections. Enriched with Ketoconazole 2% w/w, this medicated dusting powder is an effective topical treatment for conditions caused by dermatophytes and yeasts, including athlete’s foot, jock itch, ringworm, candidiasis, and tinea infections. It is developed for external use to provide soothing, itch-free skin and reduce fungal spread, making it ideal for use in humid conditions or for individuals prone to sweating and friction-related fungal outbreaks.\n\nWhat is Ketoconazole Dusting Powder?\nKetoconazole dusting powder is an antifungal medication available in a topical powder form. The active ingredient, ketoconazole 2% w/w, belongs to the class of imidazole antifungals that work by disrupting the fungal cell membrane, effectively killing the fungi or preventing its growth. The powder form helps in keeping the skin dry, reducing friction, and preventing recurrence of infections, especially in skin folds or moist areas.\n\nKetoconazole dusting powder is primarily used to treat fungal skin infections. It is effective against conditions like athlete's foot, jock itch, ringworm, and other superficial fungal infections. The powder works by inhibiting the growth of fungi and is typically applied to the affected area twice a day, or as directed by a healthcare professional.\n\nUses of KATARINA Dusting Powder\nKATARINA Dusting Powder is prescribed for the following conditions:\n\nAthlete’s foot (Tinea pedis): A fungal infection between the toes or on the soles.\n\nJock itch (Tinea cruris): Infection in the groin or inner thighs.\n\nRingworm (Tinea corporis): Circular red rash on the skin or scalp.\n\nTinea versicolor: A fungal infection causing discolored patches on the skin.\n\nCutaneous candidiasis: Yeast infection affecting skin folds.\n\nHelps in preventing fungal growth in people prone to excessive sweating and friction.\n\nSide Effects of Ketoconazole Dusting Powder\nKATARINA Dusting Powder is generally safe for most users when used as directed. However, some individuals may experience:\n\nSkin irritation\n\nRedness\n\nItching\n\nDryness or stinging at the application site\n\nIf these symptoms persist or worsen, stop usage and consult your doctor.\n\nPrecautions Before Using\n\nDo not apply the powder on broken or oozing skin.\n\nAvoid contact with eyes, nose, mouth, or mucous membranes.\n\nUse only on externally affected areas.\n\nWash and dry the area properly before application.\n\nAlways complete the course of treatment, even if symptoms subside early.\n\nIf you are pregnant or breastfeeding, consult your healthcare provider before use.\n\nNot recommended for children under 12 years unless prescribed.\n\nDrug Interactions: What Drugs Interact With Ketoconazole Powder?\nAlthough topical ketoconazole has minimal systemic absorption, interactions are rare. However, if you're using other topical medications or creams in the same area, inform your doctor or pharmacist. Avoid combining with other antifungal treatments unless advised, as it may cause skin irritation or reduce effectiveness.\n\nConclusion\nKATARINA DUSTING POWDER is your trusted solution for fast, effective, and soothing relief from fungal skin infections. Formulated with ketoconazole 2% w/w, it targets the root cause of infection, provides dryness, and prevents recurrence. With regular and appropriate use, it helps maintain healthy, itch-free skin. For optimal results, use as directed and maintain good hygiene practices. Choose KATARINA for comfort, protection, and skin confidence.",
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"description": "LONICAZOLE P is a powerful topical formulation designed to treat fungal skin infections effectively while providing rapid relief from itching and discomfort. Enriched with the antifungal potency of Luliconazole and the fast-acting anesthetic benefits of Pramoxine Hydrochloride, this dual-action cream offers both therapeutic treatment and symptomatic relief. Ideal for conditions like athlete’s foot, ringworm, jock itch, and candidiasis, LONICAZOLE P provides an advanced solution to restore skin health and comfort.\n\nKey Ingredients\nLuliconazole IP 1% w/w: A potent imidazole antifungal agent that targets and eliminates a wide range of fungal pathogens.\n\nPramoxine Hydrochloride 1% w/w: A local anesthetic that provides immediate relief from itching, burning, and pain associated with fungal infections.\n\nKey Benefits\nEffectively treats superficial fungal infections of the skin.\n\nProvides rapid and long-lasting relief from itching and irritation.\n\nReduces redness, scaling, and inflammation caused by fungal activity.\n\nCombines antifungal treatment with symptomatic relief in a single application.\n\nHelps restore the natural appearance and integrity of the skin.\n\nHow Does It Work?\nLuliconazole inhibits the synthesis of ergosterol, an essential component of fungal cell membranes. Without ergosterol, fungal cells lose structure and die, eliminating the infection.\n\nPramoxine Hydrochloride works by blocking nerve signals in the skin, thereby reducing the sensation of itchiness and discomfort almost immediately after application.\n\nDirections for Use\nClean and dry the affected area thoroughly before application.\n\nApply a thin layer of LONICAZOLE P cream to the infected area and surrounding skin once daily or as directed by your physician.\n\nRub in gently and allow the cream to absorb completely.\n\nContinue use for the full course of treatment, even if symptoms improve, to prevent recurrence.\n\nWash hands after application unless the hands are the area being treated.\n\nSide Effects\nMild burning, stinging, or redness at the site of application may occur.\n\nDryness or flaking of the skin may be observed in some cases.\n\nAllergic reactions such as rash, swelling, or itching (rare) should be reported to a healthcare provider.\n\nDiscontinue use and consult a doctor if irritation worsens or if there are signs of an allergic reaction.\n\n",
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"description": "TOPBETA GM Cream is a topical dermatological preparation specially formulated to treat a range of inflammatory and infectious skin disorders. It combines the potent anti-inflammatory action of Clobetasol Propionate, the antimicrobial efficacy of Neomycin Sulphate, and the antifungal power of Miconazole Nitrate. This makes it particularly effective in treating skin conditions where infection and inflammation coexist, such as infected eczema, fungal dermatitis, intertrigo, and athlete’s foot.\n\nKey Ingredients\nClobetasol Propionate: A strong corticosteroid that helps reduce inflammation, redness, itching, and skin irritation. It works by suppressing inflammatory chemicals in the skin.\n\nNeomycin Sulphate: A broad-spectrum antibiotic that kills or inhibits bacteria commonly responsible for secondary skin infections.\n\nMiconazole Nitrate: A powerful antifungal agent that disrupts fungal cell membranes, making it effective against yeast and dermatophyte infections.\n\nKey Benefits\nRelieves itching, swelling, and redness associated with inflammatory skin conditions\n\nTreats fungal and bacterial infections of the skin\n\nPrevents secondary infections in damaged or sensitive skin areas\n\nPromotes faster healing and restoration of normal skin\n\nIdeal for mixed infections where both fungi and bacteria are present\n\nHow Does It Work?\nTOPBETA GM Cream works through a synergistic mechanism:\n\nClobetasol Propionate suppresses the skin’s inflammatory response, helping to reduce the signs and symptoms of dermatitis, eczema, and allergic reactions.\n\nNeomycin Sulphate targets and destroys bacteria on the skin surface, preventing infections from spreading or worsening.\n\nMiconazole Nitrate acts on the fungal cell wall, stopping the growth and spread of fungi, helping resolve fungal infections at the source.\n\nTogether, these ingredients provide a comprehensive therapeutic effect against inflammation, bacterial infection, and fungal overgrowth.\n\nDirections for Use\nClean and dry the affected area thoroughly before application.\n\nApply a thin layer of the cream to the affected skin.\n\nGently massage until it is fully absorbed.\n\nUse twice daily or as directed by a healthcare professional.\n\nAvoid covering the treated area with bandages or dressings unless instructed.\n\nWash hands after application unless treating the hands.\n\nSide Effects\nAlthough well tolerated in most cases, some users may experience:\n\nMild burning or stinging at the site of application\n\nSkin thinning or dryness with prolonged use\n\nRedness, itching, or hypersensitivity reactions\n\nRare allergic responses such as rash or swelling\n\nDiscontinue use and consult a healthcare provider if any serious or persistent side effects occur.\n\nPrecautions\nFor external use only\n\nAvoid contact with eyes, nose, mouth, and mucous membranes\n\nNot recommended for use on broken or highly sensitive skin unless prescribed\n\nDo not use for extended periods without medical advice\n\nKeep out of reach of children\n\nConsult a doctor before use during pregnancy or breastfeeding\n\nConclusion\nTOPBETA GM Cream offers an effective, convenient, and targeted treatment for skin conditions involving infection and inflammation. With the combined strength of Clobetasol Propionate, Neomycin Sulphate, and Miconazole Nitrate, it provides fast relief from symptoms while addressing the root causes. Ideal for short-term use under medical guidance, it helps restore skin health, comfort, and protection.",
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