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"name": "amoxicillin 200 mg and clavulanic acid 28.5 mg",
"description": "CLAVAMOXY LS ORAL SUSPENSION is a pediatric antibiotic formulation designed to treat various bacterial infections in children. It combines Amoxycillin, a broad-spectrum penicillin antibiotic, with Clavulanic Acid, a beta-lactamase inhibitor that enhances Amoxycillin’s effectiveness. This combination provides powerful protection against bacteria that have developed resistance to standard antibiotics. It is commonly prescribed for respiratory tract infections, urinary tract infections, skin infections, and ear infections in children.\n\nKey Ingredients\nAmoxycillin (200mg)\n\nA widely used penicillin-type antibiotic that fights bacteria by inhibiting their cell wall synthesis.\n\nEffective against both gram-positive and gram-negative bacteria.\n\nClavulanic Acid (28.5mg)\n\nA beta-lactamase inhibitor that prevents bacterial enzymes from breaking down Amoxycillin.\n\nBroadens the spectrum of antibacterial activity.\n\nSterile Water for Injections IP (30 ml)\n\nActs as a solvent to reconstitute the dry powder before administration.\n\nEnsures accurate dosing and safe oral delivery.\n\nKey Benefits\nProvides a broad-spectrum antibacterial effect suitable for a variety of infections.\n\nEspecially effective in treating infections caused by beta-lactamase producing bacteria.\n\nFormulated as a liquid suspension, making it easy to administer to infants and children.\n\nOffers fast relief from symptoms like fever, pain, and inflammation related to infections.\n\nHelps prevent the recurrence of infections by eliminating the root cause.\n\nHow Does It Work?\nCLAVAMOXY LS ORAL SUSPENSION works through a dual mechanism:\n\nAmoxycillin interferes with the bacteria's ability to form cell walls, leading to the breakdown and death of the bacteria.\n\nClavulanic Acid prevents the bacteria from producing beta-lactamase enzymes, which are responsible for resisting many antibiotics.\n\nTogether, they make a potent combination that overcomes antibiotic resistance and ensures effective treatment.\n\nDirections for Use\nShake the bottle well before each use to ensure uniform suspension.\n\nAdminister the prescribed dose using a measuring spoon or syringe provided with the medication.\n\nDosage should be based on body weight and the severity of infection, as directed by a pediatrician.\n\nIt is usually taken every 8 or 12 hours, depending on the child’s medical condition.\n\nComplete the full course even if the child starts feeling better to prevent bacterial resistance.\n\nStore the reconstituted suspension in a refrigerator and use within the specified time frame (typically 7 days).\n\nDo not freeze and keep it out of reach of children.\n\nSide Effects\nDiarrhea – commonly due to changes in gut bacteria.\n\nNausea or vomiting – especially if taken on an empty stomach.\n\nSkin rash or itching – may indicate an allergic reaction.\n\nAbdominal pain or bloating – usually mild and temporary.\n\nThrush (oral fungal infection) – may occur with prolonged use.\n\nSevere allergic reactions (rare) – such as difficulty breathing or swelling of face/lips should be reported immediately.\n",
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"description": "DIOWELPREX 250 ORAL SOLUTION \nDivalproex (250mg/5ml)\nIntroduction\nDIOWELPREX 250 ORAL SOLUTION contains Divalproex (250mg/5ml), an anticonvulsant and mood-stabilizing medication used to treat various neurological and psychiatric conditions. It is particularly effective in managing epilepsy, bipolar disorder, and preventing migraine headaches.\n\nComposition\n\nDivalproex Sodium (250mg/5ml): A stable coordination compound comprised of sodium valproate and valproic acid in a 1:1 molar relationship, providing a source of valproate ion which exhibits anticonvulsant and mood-stabilizing properties.\nMechanism of Action\nDivalproex works by increasing the levels of gamma-aminobutyric acid (GABA) in the brain, an inhibitory neurotransmitter that helps calm neuronal activity. It stabilizes electrical activity in the brain, reducing the frequency and severity of seizures, stabilizing mood in bipolar disorder, and preventing migraine headaches by altering the way nerves send signals.\n\nIndications\nDIOWELPREX 250 ORAL SOLUTION is indicated for:\n\nEpilepsy: Used to control various types of seizures including complex partial seizures and simple and complex absence seizures.\nBipolar Disorder: Helps in the management of manic episodes associated with bipolar disorder.\nMigraine Prophylaxis: Used to prevent migraine headaches.\nDosage and Administration\n\nEpilepsy: The initial dose is typically 10-15 mg/kg/day, gradually increased as needed and tolerated to achieve optimal clinical response.\nBipolar Disorder: The initial dose is generally 750 mg/day, given in divided doses, adjusted according to clinical response.\nMigraine Prophylaxis: The initial dose is usually 250 mg twice daily, adjusted as necessary.\nIt is essential to follow the prescribed dosage and administration instructions provided by a healthcare professional. The oral solution should be measured accurately using a dosing syringe or cup to ensure the correct dose is administered.\nSide Effects\nCommon side effects may include:\n\nNausea\nDrowsiness\nDizziness\nTremor\nHair loss\nWeight gain\nGastrointestinal disturbances\nMore severe side effects can include:\n\nLiver damage\nPancreatitis\nThrombocytopenia (low platelet count)\nHyperammonemia (high levels of ammonia in the blood)\nPrecautions\n\nLiver Function: Regular monitoring of liver function tests is recommended due to the risk of hepatotoxicity.\nPancreatitis: Patients should be monitored for signs of pancreatitis.\nPregnancy: Divalproex is associated with an increased risk of congenital malformations and should be used during pregnancy only if absolutely necessary and prescribed by a healthcare provider.\nBleeding Disorders: Caution is advised in patients with known bleeding disorders due to the risk of thrombocytopenia.\nDrug Interactions\n\nAntiepileptic Drugs: Concurrent use with other antiepileptic drugs may require dosage adjustments.\nWarfarin: May enhance the anticoagulant effect, necessitating close monitoring of INR levels.\nTopiramate: Co-administration can lead to hyperammonemia and encephalopathy.\nAlcohol: Should be avoided as it can exacerbate the side effects of Divalproex and further impair mental and motor skills.\nConclusion\nDIOWELPREX 250 ORAL SOLUTION is an effective medication for managing epilepsy, bipolar disorder, and preventing migraines. With its active ingredient Divalproex, it helps stabilize neuronal activity and mood. Proper dosage and administration under the guidance of a healthcare professional are essential to maximize benefits and minimize potential side effects. Regular monitoring and adherence to medical advice ensure the safe and effective use of DIOWELPREX 250 ORAL SOLUTION.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order NOW\n",
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"name": "Nicorandil Tablets 5mg",
"description": "Nicorandil Tablets 5 mg is a vasodilatory anti-anginal medication widely prescribed for the management and prevention of angina pectoris (chest pain) associated with coronary artery disease (CAD). Angina results from an imbalance between the heart’s oxygen demand and supply due to restricted blood flow in the coronary arteries. Nicorandil offers a dual mechanism of action — acting both as a nitrate-like vasodilator and a potassium channel opener, making it unique among anti-anginal agents.\n\nBy improving oxygen delivery to the myocardium and reducing cardiac workload, Nicorandil 5 mg Tablets provide effective relief from anginal pain and reduce the frequency and severity of ischemic episodes. It is also beneficial in preventing future attacks, improving exercise tolerance, and enhancing the overall quality of life in patients with chronic stable angina.\n\nComposition\n\nEach tablet contains:\n\nNicorandil IP – 5 mg\n\nExcipients – q.s.\n\nNicorandil tablets are available in film-coated form to ensure stability, easy swallowing, and optimal absorption. They are manufactured in compliance with Good Manufacturing Practices (GMP) standards to ensure safety, purity, and efficacy.\n\nPharmacological Action / Mechanism of Action\n\nNicorandil exhibits a dual mechanism that makes it distinct among anti-anginal drugs:\n\nNitrate-Like Effect:\nNicorandil acts as a nitric oxide (NO) donor. Nitric oxide activates guanylate cyclase, increasing cyclic GMP (cGMP) levels in vascular smooth muscle. This leads to relaxation of blood vessels, particularly veins and large arteries, thereby reducing preload and afterload on the heart. This nitrate-like activity lowers myocardial oxygen demand.\n\nPotassium Channel Opening Effect:\nNicorandil opens ATP-sensitive potassium (KATP) channels in vascular smooth muscle, resulting in arteriolar vasodilation. This increases coronary blood flow and improves oxygen supply to ischemic heart tissues.\n\nTogether, these effects reduce cardiac workload, enhance coronary perfusion, and prevent anginal pain by correcting the oxygen supply-demand mismatch in the heart muscle.\n\nUses and Indications\n\nNicorandil Tablets 5 mg are indicated for the treatment and prevention of angina pectoris in adults, particularly:\n\nChronic Stable Angina:\n\nHelps reduce the frequency and severity of chest pain associated with exertion or emotional stress.\n\nProphylaxis of Angina Attacks:\n\nUsed regularly to prevent anginal episodes, especially in patients with known coronary artery disease.\n\nAdjunct Therapy in Ischemic Heart Disease (IHD):\n\nCan be used alongside beta-blockers, calcium channel blockers, or antiplatelet drugs for enhanced symptom control and long-term protection.\n\nImprovement of Exercise Tolerance:\n\nReduces the likelihood of anginal pain during physical activity, enabling patients to perform daily tasks comfortably.\n\nIn some clinical cases, Nicorandil is also considered for post-myocardial infarction recovery, as it improves coronary perfusion, although this is at the discretion of a cardiologist.\n\nDosage and Administration\n\nRecommended Starting Dose: 5 mg to 10 mg twice daily.\n\nMaintenance Dose: May be increased gradually to 10–20 mg twice daily, depending on clinical response and tolerance.\n\nThe tablets should be swallowed whole with water, preferably at the same times each day.\n\nNicorandil should not be stopped abruptly; dosage tapering is recommended to avoid rebound angina.\n\nAlways follow the dosage instructions provided by the physician.\n\nKey Benefits\n\nDual Mechanism for Comprehensive Relief:\nCombines nitrate-like and potassium channel-opening properties for both arterial and venous dilation, providing superior protection against anginal attacks.\n\nImproves Coronary Blood Flow:\nDilates coronary arteries, increasing oxygen delivery to ischemic myocardial tissues.\n\nReduces Cardiac Workload:\nBy decreasing preload (venous return) and afterload (arterial resistance), Nicorandil minimizes the heart’s oxygen consumption.\n\nRapid Onset of Action:\nNicorandil acts within a short duration, offering quick relief from anginal discomfort.\n\nPrevents Future Angina Episodes:\nRegular use helps maintain steady control of chest pain, improving exercise capacity and quality of life.\n\nCompatible with Other Cardiac Medications:\nCan be safely used alongside antiplatelet agents, beta-blockers, ACE inhibitors, and statins as part of comprehensive cardiac care.\n\nFavorable Safety Profile:\nCompared to nitrates, Nicorandil carries a lower risk of tolerance development, making it suitable for long-term therapy.\n\nEnhances Myocardial Protection:\nNicorandil’s KATP channel activation provides additional cardioprotective effects by improving microvascular blood flow and limiting ischemic damage during stress.\n\nPrecautions and Warnings\n\nAlthough Nicorandil is generally well-tolerated, certain precautions are advised:\n\nHypotension:\nNicorandil may cause a drop in blood pressure due to vasodilation. Caution is advised in patients with hypotension or dehydration.\n\nConcurrent Use with Nitrates:\nShould not be used together with other nitrate medications to avoid severe hypotension.\n\nOral or Gastrointestinal Ulcers:\nRarely, Nicorandil may cause ulcerations in the mouth, intestines, or skin. Treatment should be discontinued if ulceration occurs.\n\nPatients with Low Blood Volume:\nUse cautiously in individuals with hypovolemia or those on diuretics.\n\nDriving and Machinery:\nDizziness or light-headedness may occur; avoid driving until effects are known.\n\nPregnancy and Lactation:\nShould be used only if prescribed by a physician when the potential benefits outweigh the risks.\n\nPossible Side Effects\n\nNicorandil is generally safe but may cause some side effects, particularly at the start of therapy or with higher doses. Common and rare adverse reactions include:\n\nCommon Side Effects:\n\nHeadache (due to vasodilation)\n\nFlushing or warmth sensation\n\nDizziness or light-headedness\n\nNausea or mild stomach upset\n\nFatigue or weakness\n\nLess Common / Rare Side Effects:\n\nHypotension (low blood pressure)\n\nPalpitations or tachycardia\n\nMouth ulcers, anal ulcers, or skin ulceration (uncommon but serious — discontinue if occurs)\n\nRash or allergic reaction\n\nVisual disturbances (rare and usually reversible)\n\nIf any severe reaction or persistent discomfort occurs, medical attention should be sought promptly.\n\nDrug Interactions\n\nAvoid concomitant use with nitrates or phosphodiesterase type-5 inhibitors (e.g., Sildenafil, Tadalafil), as it may cause a dangerous fall in blood pressure.\n\nCaution with antihypertensive drugs or diuretics, which may enhance hypotensive effects.\n\nAlcohol consumption can potentiate dizziness or hypotension and should be limited.\n\nStorage and Handling\n\nStore below 30°C, protected from moisture and direct sunlight.\n\nKeep out of reach of children.\n\nDo not use tablets past the expiry date or if the packaging is damaged.\n\nConclusion\n\nNicorandil Tablets 5 mg offer a modern and effective approach to managing angina pectoris, providing reliable relief through their dual-action mechanism. By combining nitrate-like vasodilation with potassium channel opening, Nicorandil ensures both oxygen supply improvement and reduction of cardiac workload — the cornerstone of angina management.\n\nIt is well-tolerated, fast-acting, and suitable for long-term therapy, making it a preferred choice for patients with chronic stable angina. Regular use under medical supervision helps reduce the frequency of chest pain, improve physical endurance, and enhance the overall quality of life in individuals with coronary artery disease.",
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"description": "TELAVINCE AF 25 is primarily indicated for:\n\nHypertension (High Blood Pressure): Effectively helps in lowering elevated blood pressure.\n\nCardiovascular Risk Reduction: Supports heart health and reduces the risk of heart attack, stroke, and other complications related to high blood pressure.\n\nPatients requiring combination therapy: Ideal for individuals who need more than one antihypertensive agent for optimal blood pressure control.\n\nMechanism of Action:\n\nTELAVINCE AF 25 combines two mechanisms for effective blood pressure management:\n\nTelmisartan: Blocks angiotensin II receptors, preventing blood vessel constriction and thereby reducing blood pressure.\n\n[AF Component, e.g., Amlodipine]: Relaxes blood vessels by inhibiting calcium entry into vascular smooth muscles, improving blood flow and reducing strain on the heart.\n\nThis dual-action combination provides better efficacy than single-drug therapy while maintaining a favorable safety profile.\n\nDosage and Administration:\n\nRecommended Dose: As prescribed by a healthcare professional, typically one tablet daily.\n\nRoute: Oral, with water.\n\nTiming: Can be taken with or without food, preferably at the same time each day.\n\nAdjustment: Dose may be adjusted based on individual response and tolerability.\n\nImportant: Always follow your doctor’s instructions. Do not change the dose or stop medication without medical advice.\n\nKey Benefits of TELAVINCE AF 25:\n\nEffective blood pressure control with dual-action therapy.\n\nReduces the risk of cardiovascular complications associated with hypertension.\n\nConvenient once-daily dosing for better patient adherence.\n\nWell-tolerated with minimal side effects.\n\nSuitable for long-term use under medical supervision.\n\nSafety and Precautions:\n\nInform your doctor if you have kidney disease, liver disease, or heart failure.\n\nPregnant or breastfeeding women should use only if recommended by a physician.\n\nAvoid excessive use of potassium-containing salt substitutes.\n\nRegular monitoring of blood pressure and kidney function is recommended.\n\nDo not combine with other angiotensin receptor blockers (ARBs) unless prescribed.\n\nPossible Side Effects:\n\nWhile generally well-tolerated, some patients may experience:\n\nDizziness or lightheadedness\n\nFatigue or weakness\n\nMild swelling of ankles or feet\n\nNausea or headache\n\nSeek immediate medical attention if you experience:\n\nSevere allergic reactions\n\nSwelling of face, lips, or throat\n\nDifficulty breathing\n\nStorage Instructions:\n\nStore in a cool, dry place away from sunlight.\n\nKeep out of reach of children and pets.\n\nDo not use after the expiry date mentioned on the package.\n\nWhy Choose TELAVINCE AF 25:\n\nDeveloped by Steris Healthcare Pvt. Ltd, a trusted pharmaceutical company.\n\nEnsures quality, safety, and efficacy in every tablet.\n\nDesigned for patient convenience with once-daily dosing.\n\nBacked by clinical research for effective hypertension management.\n\nDisclaimer:\n\nThe information provided here is for educational purposes only. TELAVINCE AF 25 should be used only under medical supervision. Consult your healthcare provider for personalized advice. Side effects may vary from person to person.\n\n",
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