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{ "products": [ { "_id": "6a86e496cc4491de1ed77dfd", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Etoricoxib & Cyclobenzaprine Hydrochloride Tablets", "description": "ERITOCOX BENZ 90/5 is a fixed-dose combination tablet pairing Etoricoxib 90 mg, a selective COX-2 anti-inflammatory, with Cyclobenzaprine Hydrochloride 5 mg, a centrally acting muscle relaxant. It is prescribed for short-term relief of acute musculoskeletal problems where pain, swelling, and muscle tightness occur together — think a sudden low-back strain, a stiff neck, or a flare-up of arthritis where the surrounding muscles clamp down defensively. Rather than treating the inflammation alone or the spasm alone, this tablet addresses both mechanisms in one dose, which can mean fewer pills and a more complete response for short, acute episodes. It is a prescription-only (Schedule H) medicine, produced under WHO-GMP and ISO-certified manufacturing standards by Steris Healthcare Pvt. Ltd. Typical side effects include drowsiness, dry mouth, and mild stomach upset; because the combination carries cardiovascular, gastrointestinal, and kidney considerations, it should only be used under a doctor's supervision. This page walks through what the tablet does, how it works, correct usage, safety information, and answers to the questions people most often ask.\n\nWhat Is ERITOCOX BENZ 90/5?\n\nPain from an acute back injury, a wrenched neck, or an arthritis episode almost never travels alone — it tends to bring a tense, guarded muscle along with it that makes every movement feel worse. ERITOCOX BENZ 90/5 was formulated with that pattern in mind, folding two separate mechanisms into a single tablet rather than requiring two prescriptions.\n\nActive Ingredient\tStrength\tRole\nEtoricoxib\t90 mg\tSelective COX-2 inhibitor for inflammatory pain\nCyclobenzaprine Hydrochloride\t5 mg\tCentrally acting skeletal muscle relaxant\n\nEach tablet is manufactured by Steris Healthcare Pvt. Ltd., a WHO-GMP and ISO-certified pharmaceutical company, so every batch meets verified potency and quality benchmarks.\n\nWhy This Combination Makes Sense\n\nMusculoskeletal pain is rarely a single-track problem. When tissue is injured or irritated, inflammation flares up locally — and nearby muscles frequently respond by tightening protectively. That protective tightening, the spasm, often becomes a pain generator of its own. Treat only the inflammation and the spasm can linger; treat only the spasm and the underlying inflammation keeps driving discomfort.\n\nERITOCOX BENZ 90/5 is built to intervene on both fronts at once:\n\nEtoricoxib addresses the chemical cascade responsible for pain and swelling at the injured site.\nCyclobenzaprine works through the central nervous system to calm the muscle guarding that so often rides alongside that pain.\nMechanism of Action: How ERITOCOX BENZ 90/5 Works\n\nEtoricoxib selectively inhibits the COX-2 enzyme — the enzyme the body ramps up at sites of tissue damage or irritation to manufacture prostaglandins, the chemical messengers behind pain, swelling, and localized heat. Because it targets COX-2 specifically rather than blocking both COX-1 and COX-2 the way older, non-selective NSAIDs do, etoricoxib is designed to control inflammatory pain while leaving more of the COX-1 activity that protects the stomach lining relatively undisturbed.\n\nCyclobenzaprine Hydrochloride takes a different route entirely — its primary site of action is the brainstem, not the muscle fiber itself. By dampening excessive motor signaling sent to skeletal muscle, it reduces spasm and stiffness without producing the broad muscle weakness that a directly-acting muscle agent might cause.\n\nPut together, the tablet delivers a two-pronged effect: peripheral anti-inflammatory action from etoricoxib, layered with central muscle relaxation from cyclobenzaprine.\n\n[Reviewer placeholder: insert verified pharmacokinetic data (onset, half-life, bioavailability) once confirmed by medical/regulatory team — do not publish unverified figures.]\n\nClinical Uses of ERITOCOX BENZ 90/5\n\nA physician may prescribe this combination for short-term management of acute conditions where pain, inflammation, and spasm show up together, including:\n\nCondition\tTypical Presentation\nAcute lower back pain\tPain with associated muscle guarding/spasm\nNeck strain / cervical spasm\tStiff, restricted neck movement\nSprains, strains, overuse injuries\tMusculoskeletal trauma with inflammatory pain\nOsteoarthritis flare-ups\tJoint pain accompanied by surrounding muscle tightness\nPostural or occupational muscle pain\tWork- or posture-related inflammation and tension\nMovement restriction linked to spasm\tReduced range of motion driven by muscular guarding\n\nSuitability for any of the above must be confirmed by a doctor based on your specific diagnosis and medical history.\n\nKey Benefits of ERITOCOX BENZ 90/5\nOne tablet, two mechanisms — anti-inflammatory pain relief and muscle-spasm relief combined, simplifying an otherwise two-drug regimen.\nSite-focused inflammation control — etoricoxib's COX-2 selectivity is intended to concentrate its effect where inflammation is actually active.\nA comparatively gentler GI footprint — COX-2-selective action is generally linked to lower gastrointestinal irritation risk than older non-selective NSAIDs, though vigilance is still warranted.\nLoosens spasm-related stiffness — cyclobenzaprine's central action helps release tight, guarded muscles restricting movement.\nAids functional recovery — easing both pain and spasm can make it more realistic to resume light activity, stretching, or physiotherapy once your doctor clears you.\nStreamlined short-course dosing — a once-daily schedule (as prescribed) cuts down pill burden versus taking an NSAID and a muscle relaxant separately.\nDosage & Administration\n\nThe following is general reference information — your doctor's specific prescription always takes precedence.\n\nTake ERITOCOX BENZ 90/5 exactly as prescribed, generally once a day, with or without food.\nSwallow the tablet whole with water; avoid crushing or chewing unless your doctor tells you otherwise.\nTreatment is typically short — anywhere from a few days to roughly two weeks — reflecting the acute, self-limiting nature of most pain-and-spasm episodes.\nIf a dose is missed, take it as soon as you remember, but skip it entirely if the next dose is nearly due. Never double up to make up for a missed dose.\nDo not extend the treatment period or adjust your dose independently, even if symptoms haven't fully resolved.\nSide Effects of ERITOCOX BENZ 90/5\nCommon Side Effects\nDrowsiness or sleepiness\nDizziness\nDry mouth\nHeadache\nStomach discomfort or indigestion\nNausea\nFatigue\nMild elevation in blood pressure in some individuals\nSerious Side Effects — Seek Medical Help Promptly\nSigns of gastrointestinal bleeding, such as black stools or vomiting blood\nA severe allergic reaction — swelling of the face or throat, breathing difficulty, or widespread rash\nChest pain, irregular heartbeat, or other symptoms suggestive of a cardiovascular event\nYellowing of the skin or eyes, which may point to liver involvement\nA noticeable drop in urine output, which may suggest kidney impairment\nSevere dizziness, confusion, or fainting\n\nIf any of these serious symptoms appear, stop the medicine and get medical attention immediately.\n\nPrecautions & Warnings\nShare your full medical history with your doctor before starting, including any heart, kidney, or liver conditions.\nUse cautiously — or avoid altogether — if you have a history of stomach ulcers or gastrointestinal bleeding.\nGenerally not advised for people with uncontrolled high blood pressure, existing heart disease, or a prior stroke, unless a doctor specifically clears its use.\nSteer clear of alcohol, since it can amplify cyclobenzaprine's sedative effect and add to gastrointestinal risk.\nCyclobenzaprine may cause drowsiness or dizziness — hold off on driving or operating machinery until you know how the tablet affects you.\nDon't combine ERITOCOX BENZ 90/5 with other NSAIDs, painkillers, or sedating medicines without checking with your doctor first.\nAvoid the medicine if you have known hypersensitivity to etoricoxib, cyclobenzaprine, or related compounds.\nNot generally recommended during pregnancy or breastfeeding unless a doctor specifically advises otherwise.\nAvoid combining with MAO inhibitors, or using shortly after stopping them.\nDrug Interactions to Flag With Your Doctor\n\nDisclose every prescription medicine, over-the-counter product, and supplement you take. Extra caution is needed around medicines affecting:\n\nBlood pressure regulation\nKidney function\nBlood clotting\nCentral nervous system activity (sedatives, other muscle relaxants)\nLiver metabolism\nOther anti-inflammatory or pain-relief medicines\nConclusion\n\nERITOCOX BENZ 90/5 brings Etoricoxib 90 mg and Cyclobenzaprine Hydrochloride 5 mg together to tackle a problem that rarely presents as a single issue — pain, inflammation, and muscle spasm that reinforce one another in acute musculoskeletal conditions. By acting on both the inflammatory and muscular sides of that cycle, it offers a more rounded short-term response than either ingredient could provide alone.\n\nGiven the genuine cardiovascular, gastrointestinal, kidney, and central-nervous-system considerations involved, ERITOCOX BENZ 90/5 is meant strictly for short, doctor-supervised courses — not casual or extended self-treatment. Always check with your doctor to confirm whether this combination is right for your condition, medical history, and current medications.\n\nPrescription only – consult your doctor.\n\nFrequently Asked Questions (Google & AI Mode / Voice Search Optimized)\n\n1. What is ERITOCOX BENZ 90/5 used for? It's typically prescribed for short-term relief of acute musculoskeletal issues — such as back pain, neck strain, or an arthritis flare-up — where pain, inflammation, and muscle spasm show up together.\n\n2. Is ERITOCOX BENZ 90/5 a muscle relaxant? It's a combination tablet: the muscle-relaxing effect comes from its Cyclobenzaprine Hydrochloride component, while Etoricoxib supplies the pain-relieving, anti-inflammatory action.\n\n3. Is Etoricoxib a strong painkiller? Etoricoxib is an effective selective COX-2 inhibitor typically used for moderate inflammation-related pain, such as arthritis or an acute musculoskeletal injury. Its appropriateness for your level of pain should be assessed by a doctor.\n\n4. Is Etoricoxib safe for the kidneys? As with other NSAIDs, etoricoxib can influence kidney function, particularly with extended use, higher doses, dehydration, or existing kidney disease. It should be used carefully and only under medical guidance if kidney health is a concern.\n\n5. Should ERITOCOX BENZ 90/5 be taken in the morning or at night? It's usually taken once a day at a time your doctor sets. Since cyclobenzaprine can cause drowsiness, many doctors lean toward an evening dose — but always stick to your specific prescription.\n\n6. What are the common side effects of ERITOCOX BENZ 90/5? Frequently reported effects include drowsiness, dizziness, dry mouth, headache, stomach discomfort, and mild fatigue. Most fade on their own, but persistent symptoms should be reported to your doctor.\n\n7. How fast does ERITOCOX BENZ 90/5 start working? Etoricoxib tends to absorb fairly quickly, and many people feel pain relief within roughly an hour, though onset can vary by individual and whether the tablet is taken with food.\n\n8. What should be avoided while on ERITOCOX BENZ 90/5? Skip alcohol, avoid taking other NSAIDs or painkillers without medical advice, and hold off on driving or operating machinery if you're feeling drowsy or dizzy.\n\n9. How many days can ERITOCOX BENZ 90/5 be taken? It's usually prescribed for a short stretch — a few days up to around two weeks — matching how acute conditions typically resolve. Anything longer needs your doctor's review.\n\n10. What are the benefits of ERITOCOX BENZ 90/5? It delivers combined relief from pain, inflammation, and muscle spasm in one tablet, which can make it easier to move normally and get back to daily activity sooner when used as directed.\n\n11. How safe is ERITOCOX BENZ 90/5? Taken exactly as prescribed and for the recommended duration, it's generally considered safe for most adults. It does carry cardiovascular, gastrointestinal, kidney, and liver-related risks that call for medical supervision, especially if you already have related conditions.\n\n12. Can ERITOCOX BENZ 90/5 be used for knee pain? Yes — its etoricoxib component is commonly used for joint pain tied to osteoarthritis or an acute injury, including the knee, by reducing the underlying inflammation. A doctor should confirm suitability first.\n\n13. Does ERITOCOX BENZ 90/5 cause drowsiness? Yes — drowsiness and dizziness are known effects linked to its cyclobenzaprine component. Avoid driving or tasks requiring full alertness until you know how it affects you.\n\n14. Can ERITOCOX BENZ 90/5 be bought without a prescription? No. This is a prescription-only medicine meant to be taken solely under a qualified doctor's supervision — it isn't meant for self-prescribing or extended use without medical oversight.\n\n15. Can ERITOCOX BENZ 90/5 be taken with food? It can generally be taken with or without food, though taking it with food may ease stomach discomfort for some people. Follow your doctor's specific instructions.\n\n16. Is ERITOCOX BENZ 90/5 habit-forming? Cyclobenzaprine isn't considered addictive with typical short-term use, but the tablet should still be taken only for the prescribed duration and not restarted on your own without medical advice.\n\n17. Who should avoid taking ERITOCOX BENZ 90/5? People with active stomach ulcers, significant heart, kidney, or liver disease, known hypersensitivity to NSAIDs, or those who are pregnant or breastfeeding should avoid it unless a doctor specifically clears its use.", "price": 222.0, "discountamount": 67.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2495, "imageuri": "https://productimages.withfloats.com/actual/6a86e4990f089c4695c57658.png", "tileimageuri": "https://productimages.withfloats.com/tile/6a86e4990f089c4695c57658.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-08-20T11:27:18.403Z", "updatedon": "2026-08-20T11:27:18.403Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/etoricoxib-cyclobenzaprine-hydrochloride-tablets/2495", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "ERITOCOX BENZ 90/5", "category": "", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6a5de55aa467a7e64774de83", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Teneligliptin 20mg,Pioglitazone 15mg & Metformin Hydrochloride (Sustained Release) 1000mg Tablets", "description": "TENELIGOLD PM 1000 brings together three antidiabetic agents — Teneligliptin 20 mg, Pioglitazone 15 mg, and Metformin Hydrochloride (Sustained Release) 1000 mg — in a single tablet built to support glycemic control in adults living with Type 2 Diabetes Mellitus (T2DM). Rather than relying on one pathway, this triple-action formula addresses blood glucose from several angles at once, offering a more rounded approach to sugar management.\n\nProduced under strict pharmaceutical quality benchmarks, TENELIGOLD PM 1000 works to sharpen the body's response to insulin, prompt insulin release in step with rising glucose, and rein in the liver's excess sugar output. It's typically brought into a treatment plan once lifestyle changes and single-drug therapy no longer keep blood sugar within target range.\n\nComposition\n\nEach sustained-release tablet delivers:\n\nTeneligliptin – 20 mg\nPioglitazone – 15 mg\nMetformin Hydrochloride (Sustained Release) – 1000 mg\n\nDosage Form: Sustained Release Tablets\n\nHow TENELIGOLD PM 1000 Works\n\nThis tablet pairs three well-known antidiabetic molecules so their effects complement one another.\n\n1. Teneligliptin 20 mg\n\nA DPP-4 inhibitor, Teneligliptin raises the body's incretin hormone activity, which in turn:\n\nTriggers insulin output only when glucose levels are elevated\nCurbs glucagon release\nFlattens the post-meal blood sugar rise\nKeeps hypoglycemia risk low\n\n2. Pioglitazone 15 mg\n\nBelonging to the Thiazolidinedione (TZD) family, Pioglitazone:\n\nSharpens the body's sensitivity to insulin\nHelps muscle tissue take up and use glucose more effectively\nCuts down insulin resistance\nAids sustained glycemic management over time\n\n3. Metformin SR 1000 mg\n\nA Biguanide-class agent, Metformin SR:\n\nSlows the liver's glucose output\nLimits how much glucose the intestines absorb\nBoosts insulin responsiveness\nDelivers steady blood sugar control across the day\n\nBecause it's released gradually, the sustained-release format is also gentler on the stomach than immediate-release versions.\n\nBenefits of TENELIGOLD PM 1000\n\nWell-Rounded Blood Sugar Control The three-pronged formula works to steady both fasting glucose and the spikes that follow meals.\n\nStronger HbA1c Improvement Used appropriately, this combination therapy may lower HbA1c more than a single-agent approach would.\n\nSharper Insulin Response Pioglitazone's role in easing insulin resistance means the insulin the body produces (or receives) does more work.\n\nSteady, All-Day Coverage Metformin SR's gradual release keeps blood sugar levels more consistent throughout the day.\n\nOne Tablet, Three Medicines Combining proven antidiabetic drugs into a single pill can make treatment simpler and support better adherence.\n\nA Foundation for Long-Term Care Sustained glycemic control, paired with healthy lifestyle habits, may help lower the risk of diabetes-related complications down the line.\n\nIndications\n\nTENELIGOLD PM 1000 is intended as an add-on to diet and exercise for improving blood sugar control in adults with Type 2 Diabetes Mellitus, particularly where a physician determines combination therapy is the right course.\n\nIt is not meant for Type 1 Diabetes Mellitus or diabetic ketoacidosis.\n\nKey Features\nTriple-combination antidiabetic tablet\nSustained-release Metformin component\nSupports both fasting and post-meal glucose control\nImproves insulin sensitivity\nEncourages glucose-responsive insulin release\nLowers hepatic glucose output\nOnce-daily dosing convenience, as prescribed\nManufactured to rigorous quality standards\nSuited to long-term diabetes management under medical guidance\nWho May Benefit?\n\nPhysicians may consider TENELIGOLD PM 1000 for adult T2DM patients who:\n\nContinue to have unmanaged blood sugar despite two-drug therapy\nNeed better HbA1c outcomes\nShow marked insulin resistance\nRequire broader glycemic coverage\nWould benefit from a sustained-release metformin option\n\nEvery treatment decision should be tailored by the prescribing doctor.\n\nDirections for Use\nTake exactly as directed by your physician.\nSwallow the tablet whole with water.\nNever crush, chew, or split the sustained-release tablet.\nTaking it with food is generally advised to ease stomach upset.\nPair the medicine with your prescribed diet and exercise plan for best results.\nPossible Side Effects\n\nAs with any medicine, TENELIGOLD PM 1000 can cause side effects, though not everyone will experience them.\n\nCommonly reported:\n\nNausea\nDiarrhea\nStomach discomfort\nHeadache\nSlight weight gain\nSwelling in the extremities (peripheral edema), linked mainly to pioglitazone\n\nLess common but serious:\n\nLactic acidosis (a metformin-related risk, more likely in vulnerable patients)\nWorsening heart failure (associated with pioglitazone in select patients)\nAllergic reactions\nAbnormal liver function\n\nSeek urgent medical care if severe weakness, breathing difficulty, chest pain, or ongoing abdominal pain develops.\n\nPrecautions\n\nTell your healthcare provider before starting TENELIGOLD PM 1000 if you have any of the following:\n\nKidney disease\nLiver disease\nHeart failure\nBladder cancer, present or past\nPancreatitis\nVitamin B12 deficiency\nSevere dehydration\nAn upcoming surgery or imaging test involving iodinated contrast dye\n\nRoutine checks of blood glucose, HbA1c, kidney function, liver function, and related markers are advised throughout treatment.\n\nStorage Instructions\nStore below 30°C.\nKeep away from moisture and direct sunlight.\nLeave in the original packaging.\nStore out of children's reach.\nWhy Choose TENELIGOLD PM 1000?\n\nTENELIGOLD PM 1000 brings three established antidiabetic medicines together in one sustained-release tablet, giving physicians a way to simplify a patient's regimen while still addressing multiple facets of Type 2 Diabetes. Through its complementary mechanisms, it offers a well-rounded route to blood sugar control for suitably selected adult patients under medical supervision.\n\nFrequently Asked Questions (FAQs)\n\nWhat is TENELIGOLD PM 1000 used for? It's prescribed to help manage Type 2 Diabetes Mellitus in adults whose blood sugar needs combination therapy alongside diet and exercise.\n\nIs TENELIGOLD PM 1000 meant to be taken every day? Yes, exactly as your physician prescribes. Don't adjust the dose on your own.\n\nCan TENELIGOLD PM 1000 lead to low blood sugar? Taken alone, the hypoglycemia risk is generally low, though it can rise if combined with insulin or sulfonylureas.\n\nCan I stop the medicine once my sugar levels normalize? No — diabetes is a long-term condition. Keep taking the medicine unless your doctor says otherwise.\n\nIs this medicine right for Type 1 Diabetes? No. It's formulated only for adults with Type 2 Diabetes Mellitus.\n\nShould TENELIGOLD PM 1000 be taken with food? Yes, taking it with meals is generally recommended to reduce stomach-related side effects.\n\nDoes it help bring down HbA1c? Yes — used as directed alongside lifestyle changes, it can support meaningful HbA1c improvement.\n\nPrescription only – consult your doctor.\n\n", "price": 385.0, "discountamount": 95.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2473, "imageuri": "https://productimages.withfloats.com/actual/6a5de55cdc76c6268e3fe287.png", "tileimageuri": "https://productimages.withfloats.com/tile/6a5de55cdc76c6268e3fe287.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-07-20T09:07:38.732Z", "updatedon": "2026-07-20T09:07:38.732Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//teneligliptin-20mg-pioglitazone-15mg-metformin-hydrochloride-sustained-release-1000mg-tablets/2473", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "TENELIGOLD PM 1000", "category": "DIABETIC RANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6a50a30c9e1ef0fb4df551b0", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "dorzolamide eye drops ip", "description": "Dorzolamide eye drops IP are a prescription ophthalmic solution used to lower elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. Dorzolamide belongs to a class of drugs called carbonic anhydrase inhibitors, which work by reducing the production of aqueous humor (the fluid inside the eye), thereby lowering pressure within the eye. It is typically used two to three times daily and begins measurably lowering eye pressure within about 2 hours, though consistent long-term use is essential for sustained control. Common side effects include a temporary bitter or unusual taste in the mouth, burning or stinging on instillation, and blurred vision. Because dorzolamide is chemically a sulfonamide derivative, it should be used cautiously in patients with known sulfa allergies or significant kidney impairment, and only under an ophthalmologist's supervision. It is a Schedule H prescription-only medicine in India.\n\nWhat Is Dorzolamide Eye Drops IP?\nDorzolamide Eye Drops IP is a topical prescription medication used primarily to manage glaucoma and ocular hypertension — conditions characterized by abnormally elevated pressure inside the eye that, if left uncontrolled, can damage the optic nerve and lead to progressive, irreversible vision loss.\nThe “IP” designation indicates the formulation conforms to standards set out in the Indian Pharmacopoeia, ensuring consistent quality, purity, and potency.\nDorzolamide belongs to the carbonic anhydrase inhibitor (CAI) class of anti-glaucoma medications. Unlike oral carbonic anhydrase inhibitors (such as acetazolamide), which act systemically and often cause more pronounced side effects, topical dorzolamide is designed to act locally within the eye, offering effective IOP reduction with comparatively lower systemic exposure — though some systemic absorption can still occur.\nIt is frequently prescribed either as a standalone treatment or in combination with other IOP-lowering agents, such as beta-blockers (e.g., timolol) or prostaglandin analogues, when a single agent does not achieve adequate pressure control.\n\nHow Does Dorzolamide Work? (Mechanism of Action)\n\nAqueous humor production – The ciliary body inside the eye continuously produces aqueous humor, the clear fluid that maintains intraocular pressure and nourishes ocular tissues.\nCarbonic anhydrase enzyme – This enzyme, found in the ciliary body, plays a key role in the chemical reactions that generate bicarbonate ions, which drive fluid secretion into the eye.\nEnzyme inhibition – Dorzolamide inhibits carbonic anhydrase (specifically the II isoenzyme) within the ciliary processes.\nReduced fluid production – With the enzyme inhibited, bicarbonate-dependent fluid transport slows down, resulting in decreased aqueous humor formation.\nLowered intraocular pressure – Less fluid production means less pressure buildup inside the eye, helping protect the optic nerve from pressure-related damage over time.\n\n\nClinical Indications\nIndicationDetailsOpen-angle glaucomaPrimary indication; helps control chronic elevated IOPOcular hypertensionUsed to reduce elevated eye pressure even before glaucoma-related damage occursAdjunct therapyCombined with beta-blockers or prostaglandin analogues when monotherapy is insufficientPost-laser or post-surgical IOP spikesSometimes used short-term under specialist guidance\n\nDosage & Administration\nParameterRecommendationStandard dose (monotherapy)One drop in the affected eye(s), three times dailyStandard dose (with other IOP-lowering drops)Often reduced to twice daily when combined, per doctor's instructionsOnset of actionMeasurable IOP reduction typically begins within about 2 hoursPeak effectGenerally within a few hours of instillationIf using multiple eye dropsSpace different eye medications at least 10 minutes apartMissed doseApply as soon as remembered; skip if near the next scheduled dose — do not double upDuration of useLong-term, ongoing therapy as glaucoma is a chronic condition requiring continuous management\nNote: Consistency is critical — missed doses can allow intraocular pressure to rise, increasing the risk of progressive optic nerve damage.\n\nKey Benefits\n\nEffectively lowers intraocular pressure in both glaucoma and ocular hypertension\nActs locally in the eye, generally producing lower systemic side effects compared to oral carbonic anhydrase inhibitors\nCan be used as monotherapy or in combination with other classes of glaucoma medication for enhanced pressure control\nHelps protect the optic nerve from pressure-related damage with consistent long-term use\nAvailable in a well-established, pharmacopoeia-standardized formulation (IP grade)\nSuitable for long-term, chronic disease management in glaucoma patients\n\n\nPrecautions\n\nUse strictly as prescribed and do not adjust dosing without consulting your ophthalmologist\nInform your doctor if you have a known sulfonamide (sulfa) allergy, since dorzolamide is chemically related to sulfa drugs\nUse with caution in patients with significant kidney (renal) impairment, due to potential for systemic absorption\nNot typically recommended in patients with severe corneal disease without specialist evaluation\nIf using contact lenses, remove before instillation and reinsert only after the interval advised by your doctor\nRegular eye pressure monitoring and follow-up visits are essential during treatment\nInform your doctor of all other eye medications and systemic drugs you are using\nAvoid touching the dropper tip to the eye or any surface to prevent contamination\n\n\nSide Effects\nCommon (Usually Mild and Temporary)\n\nTemporary bitter or unusual taste in the mouth after application\nBurning or stinging sensation on instillation\nBlurred vision immediately after use\nEye redness or itching\nMild eye discomfort\n\nLess Common / Serious (Consult Your Doctor Promptly)\n\nSigns of an allergic reaction (rash, swelling, severe itching)\nPersistent eye pain or significant vision changes\nSigns of corneal problems (persistent redness, discharge, sensitivity to light)\nSystemic effects related to sulfonamide sensitivity, in rare cases\n\nIf any serious or persistent symptom occurs, discontinue use and contact your ophthalmologist immediately.\n\nComparison: Dorzolamide vs. Other Anti-Glaucoma Therapies\nTreatmentClassMechanismKey ConsiderationDorzolamide eye dropsCarbonic anhydrase inhibitorReduces aqueous humor productionSulfa-related caution; often used as adjunct therapyTimolol eye dropsBeta-blockerReduces aqueous humor production via a different pathwayCaution in asthma, heart conditionsLatanoprost / prostaglandin analoguesProstaglandin analogueIncreases aqueous humor outflowOnce-daily dosing; may darken iris/eyelash growthBrimonidineAlpha-2 agonistReduces production and increases outflowCan cause drowsiness, dry mouthOral acetazolamideSystemic carbonic anhydrase inhibitorReduces aqueous humor production systemicallyMore pronounced systemic side effects than topical dorzolamide\n\nKey Statistics (Placeholder — Pending Clinical Reviewer Verification)\nMetricValueAverage IOP reduction achieved with dorzolamide monotherapy[Placeholder – insert verified clinical trial statistic]Prevalence of open-angle glaucoma in adults over 40[Placeholder – insert epidemiological reference]Proportion of patients requiring combination glaucoma therapy[Placeholder – insert verified reference]\nAll statistics above are placeholders and must be verified and populated by a qualified clinical reviewer prior to publication.\n\nExpert Insight\n\n[Placeholder — Expert quote pending. To be added only after review and approval by a licensed ophthalmologist/medical reviewer associated with Steris Healthcare. Do not fabricate or publish without sign-off.]\n\n\nPrice of Dorzolamide Eye Drops IP\nThe price of dorzolamide eye drops IP varies depending on pack size, brand, and region. For current pricing, availability, and prescription verification, please consult your ophthalmologist or an authorized pharmacy.\nPrescription only – consult your doctor.\n\nConclusion\nDorzolamide Eye Drops IP play a well-established role in the long-term management of glaucoma and ocular hypertension, offering targeted, localized reduction of intraocular pressure through carbonic anhydrase inhibition. Whether used alone or alongside other classes of IOP-lowering medication, consistent, correctly timed use is essential to protect the optic nerve from progressive, irreversible damage. Because dorzolamide is a sulfonamide derivative with potential for systemic absorption, patients with sulfa allergies or kidney impairment should discuss suitability carefully with their ophthalmologist. As with all glaucoma therapy, regular monitoring and adherence to the prescribed regimen — rather than occasional or as-needed use — are what ultimately safeguard long-term vision.\n\nFrequently Asked Questions\n\n1. What is dorzolamide eye drops used for?\nDorzolamide eye drops are used to lower elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension, helping protect the optic nerve from pressure-related damage.\n\n2. How long does it take dorzolamide to lower eye pressure?\nDorzolamide typically begins measurably lowering intraocular pressure within about 2 hours of application, though consistent, long-term use is needed to maintain stable pressure control over time.\n\n3. What are the side effects of dorzolamide?\nCommon side effects include a temporary bitter or unusual taste in the mouth, burning or stinging upon application, blurred vision, and mild eye redness or discomfort. Less commonly, allergic reactions or persistent eye irritation can occur and should be reported to a doctor.\n4. Does dorzolamide affect the kidneys?\nDorzolamide is a sulfonamide derivative, and although it is applied topically with generally low systemic absorption, caution is advised in patients with significant kidney impairment. Patients with known kidney disease or sulfa allergies should inform their doctor before starting treatment.\n\n5. How often should dorzolamide eye drops be used?\nDorzolamide is typically used three times daily as monotherapy, or twice daily when combined with other glaucoma medications, exactly as directed by your ophthalmologist.\n\n6. Can dorzolamide be used with other glaucoma eye drops?\nYes, dorzolamide is commonly combined with beta-blockers, prostaglandin analogues, or other IOP-lowering agents when a single medication does not achieve adequate pressure control. Different eye drops should be spaced at least 10 minutes apart.\n\n7. Is dorzolamide safe for long-term use?\nYes, dorzolamide is designed for long-term, ongoing use in chronic glaucoma management, provided it is used under regular ophthalmologist supervision with periodic eye pressure monitoring.\n\n8. Who should not use dorzolamide eye drops?\nPatients with known hypersensitivity to sulfonamides, significant kidney impairment, or specific contraindications identified by their doctor should use dorzolamide only under close medical supervision, if at all.\n\n9. Does dorzolamide cause blurred vision?\nTemporary blurred vision can occur immediately after applying dorzolamide. This is usually short-lived, but if it persists, you should consult your ophthalmologist.\n\n10. Can dorzolamide eye drops be used with contact lenses?\nIt's generally recommended to remove contact lenses before applying dorzolamide and reinsert them only after the interval advised by your doctor, as certain preservatives in eye drops can affect contact lens materials.\n\n11. What happens if I miss a dose of dorzolamide?\nApply the missed dose as soon as you remember, unless it is almost time for your next scheduled dose — in that case, skip the missed dose and continue your regular schedule. Do not double up doses.\n\n12. Why does dorzolamide cause a bitter taste?\nThe bitter taste occurs because a small amount of the eye drop drains through the tear duct into the nasal passage and throat, where it can be tasted. This is a recognized, generally harmless effect of topical carbonic anhydrase inhibitors.\n13. Is dorzolamide the same as timolol eye drops?\nNo. Dorzolamide is a carbonic anhydrase inhibitor, while timolol is a beta-blocker. Both lower eye pressure but through different mechanisms, and they are sometimes prescribed together for enhanced effect.\n\n14. Can dorzolamide be used during pregnancy?\nUse during pregnancy or breastfeeding should only occur under direct medical supervision. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding before starting dorzolamide.\n\n15. How is dorzolamide different from oral glaucoma medications?\nTopical dorzolamide acts locally in the eye and generally causes fewer systemic side effects than oral carbonic anhydrase inhibitors like acetazolamide, which act throughout the body and can cause more pronounced systemic effects.\n16. Can stopping dorzolamide suddenly cause problems?\nStopping dorzolamide abruptly can allow intraocular pressure to rise again, increasing the risk of progressive optic nerve damage. Always consult your ophthalmologist before discontinuing treatment.\n\n17. Does dorzolamide need to be refrigerated?\nStorage requirements can vary by brand and formulation; always follow the storage instructions printed on your specific product's packaging or as advised by your pharmacist.", "price": 350.0, "discountamount": 105.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2470, "imageuri": "https://productimages.withfloats.com/actual/6a50a30e9569e07de66607f4.png", "tileimageuri": "https://productimages.withfloats.com/tile/6a50a30e9569e07de66607f4.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-07-10T07:45:16.262Z", "updatedon": "2026-07-10T07:45:16.262Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//dorzolamide-eye-drops-ip/2470", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CIPVISION DORZONIX 2%", "category": "Opthalmology Range", "tags": [ "dorzolamide eye drops ip", "dorzolamide eye drops", "dorzolamide eye drops uses", "dorzolamide eye drops uses in hindi", "dorzolamide eye drops price", "dorzolamide eye drops ip", "dorzolamide eye drops brand name", "dorzolamide eye drops brands" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6a5092283075a19d4f2db6bd", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Cyclosporine Eye Drops 0.05% w/v", "description": "Cyclosporine eye drops 0.05% are a prescription ophthalmic emulsion used to treat chronic dry eye disease (keratoconjunctivitis sicca) caused by ocular surface inflammation. Unlike lubricating tear substitutes that only manage symptoms, cyclosporine works as a calcineurin-inhibitor immunomodulator that calms the underlying inflammation suppressing your eyes' natural tear production. It is not a steroid. The standard dose is one drop in each affected eye, twice daily, about 12 hours apart, and visible improvement in tear production typically takes 6–12 weeks, with full benefit sometimes taking up to 3–6 months of consistent use. Common side effects include temporary burning, stinging, redness, and watery eyes at the time of instillation. It is a Schedule H prescription-only medicine in India and should be used only under a qualified ophthalmologist's guidance.\n\nWhat Is Cyclosporine Eye Drops 0.05%?\nCyclosporine eye drops 0.05% (ophthalmic emulsion) is a prescription formulation designed to manage chronic dry eye disease, a condition in which the eyes fail to produce enough tears or produce tears of poor quality, often because of an underlying inflammatory process on the ocular surface and in the lacrimal (tear-producing) gland.\nThis formulation is commonly prescribed for patients whose dry eye is presumed to be due to ocular inflammation — for example, those with moderate to severe dry eye, keratoconjunctivitis sicca, or dry eye associated with conditions like Sjögren's syndrome, that has not responded adequately to artificial tears alone.\nCyclosporine belongs to a class of drugs called calcineurin inhibitors. It differs fundamentally from corticosteroid eye drops, which suppress inflammation broadly and carry risks like raised intraocular pressure and cataract formation with long-term use. Cyclosporine instead selectively dampens the T-cell-mediated inflammatory response that is thought to suppress tear gland function, allowing the eye's own tear-producing mechanism to gradually recover.\n\nHow Do Cyclosporine Eye Drops Work? (Mechanism of Action)\n\nInflammation on the ocular surface – In chronic dry eye, T-lymphocytes infiltrate the conjunctiva and lacrimal gland, triggering a self-perpetuating inflammatory cycle.\nCalcineurin inhibition – Cyclosporine binds to a cellular protein (cyclophilin) and blocks calcineurin, an enzyme required to activate T-cells.\nReduced T-cell activation – With calcineurin blocked, T-cells cannot produce the inflammatory signals (such as interleukin-2) that damage the lacrimal gland and conjunctival tissue.\nRestoration of tear production – As local inflammation subsides over weeks to months, the lacrimal gland's ability to produce natural tears gradually improves.\nImproved tear film stability – With reduced inflammation and increased natural tear volume, patients typically notice less dryness, grittiness, and ocular surface damage over time.\n\nThis is why cyclosporine drops are described as disease-modifying for dry eye rather than purely symptomatic — they address a root inflammatory cause instead of simply lubricating the eye.\n\nClinical Indications\nIndicationDetailsChronic dry eye disease (keratoconjunctivitis sicca)Primary approved use; especially where tear production is suppressed due to ocular inflammationModerate to severe dry eye not controlled by artificial tearsSecond-line option when lubricants alone are insufficientDry eye associated with autoimmune conditionsE.g., Sjögren's syndrome-related dry eye, under specialist supervisionPost-refractive surgery dry eye (select cases)Sometimes used off-label under ophthalmologist guidance\n\nDosage & Administration\nParameterRecommendationStandard doseOne drop in each affected eye, twice dailyDosing intervalApproximately 12 hours apartContact lens useRemove lenses before instillation; wait at least 15 minutes before reinsertingOnset of noticeable effectUsually 6–12 weeksFull therapeutic benefitMay take up to 3–6 months of continuous useMissed doseContinue with next scheduled dose; do not double upDiscontinuationOnly under medical advice — symptoms may return if stopped prematurely\nNote: Cyclosporine eye drops are for long-term, continuous use as directed by your ophthalmologist. Improvement is gradual, not immediate, and consistent daily use is essential for benefit.\n\nKey Benefits\n\nTargets the underlying inflammatory cause of chronic dry eye rather than only masking symptoms\nCan increase natural tear production over sustained use\nGenerally well tolerated for long-term use, since it is not a steroid and does not carry steroid-related risks like elevated eye pressure or cataract with routine use\nMay reduce dependence on frequent artificial tear instillation over time\nSuitable for long-term maintenance therapy in chronic, relapsing dry eye disease\nCan improve comfort during visually demanding tasks (screen use, reading, driving) affected by chronic dryness\n\n\nPrecautions\n\nUse strictly as prescribed by an ophthalmologist; do not self-medicate\nNot intended for immediate relief of dry eye symptoms — artificial tears may be used concurrently for interim comfort as advised by your doctor\nShould not be used in the presence of an active ocular infection unless specifically directed by a physician\nInform your doctor if you are pregnant, breastfeeding, or have any known hypersensitivity to cyclosporine or emulsion components\nAvoid touching the dropper tip to the eye or any surface to prevent contamination\nIf wearing contact lenses, remove before application and reinsert only after 15 minutes\nDo not use expired or previously opened single-use vials, if applicable to your product format\nRegular ophthalmic follow-up is recommended to monitor treatment response\n\n\nSide Effects\nCommon (Usually Mild and Temporary)\n\nBurning or stinging sensation upon instillation\nEye redness\nWatery eyes (excessive tearing)\nEye discomfort or a feeling of something in the eye\nTemporary blurred vision immediately after application\n\nLess Common / Serious (Consult Your Doctor Promptly)\n\nPersistent or worsening eye pain\nSigns of eye infection (discharge, significant redness, swelling)\nVisual disturbance that does not resolve\nSigns of an allergic reaction (eyelid swelling, itching, rash)\n\nIf any serious or persistent symptom occurs, discontinue use and consult your ophthalmologist immediately.\n\nComparison: Cyclosporine Eye Drops vs. Other Dry Eye Treatments\nTreatmentMechanismOnset of ActionLong-Term Use ProfileCyclosporine 0.05% dropsCalcineurin inhibitor; reduces inflammation, restores natural tear productionWeeks to monthsGenerally suitable for continuous long-term useArtificial tears / lubricantsSymptomatic lubrication onlyImmediate, short-livedSafe but does not address inflammation; frequent reapplication neededCorticosteroid eye dropsBroad anti-inflammatory actionFast (days)Not recommended for long-term use due to risk of raised IOP, cataractLifitegrast ophthalmic solutionLFA-1 antagonist; blocks a different inflammatory pathwayWeeksAlternative option, mechanism differs from cyclosporine\n\nKey Statistics (Placeholder — Pending Clinical Reviewer Verification)\nMetricValueReported patients showing improved tear production at 6 months[Placeholder – insert verified clinical trial statistic]Prevalence of chronic dry eye disease in adults[Placeholder – insert epidemiological reference]Average time to symptomatic improvement[Placeholder – insert verified reference range]\nAll statistics above are placeholders and must be verified and populated by a qualified clinical reviewer prior to publication.\n\nExpert Insight\n\n[Placeholder — Expert quote pending. To be added only after review and approval by a licensed ophthalmologist/medical reviewer associated with Steris Healthcare. Do not fabricate or publish without sign-off.]\n\n\nPrice of Cyclosporine Eye Drops 0.05%\nThe price of cyclosporine eye drops 0.05% varies depending on pack size, brand, and region. For current pricing, availability, and prescription verification, please consult your ophthalmologist or authorized pharmacy.\nPrescription only – consult your doctor.\n\nConclusion\nCyclosporine eye drops 0.05% represent a meaningful shift in how chronic dry eye disease is managed — moving beyond temporary lubrication to address the underlying inflammatory process that suppresses natural tear production. For patients with moderate to severe dry eye that hasn't responded well to artificial tears alone, this calcineurin-inhibitor therapy offers a disease-modifying option that, with consistent long-term use, can meaningfully improve ocular comfort and tear film health. Because benefits build gradually over weeks to months, patience and adherence to the prescribed twice-daily regimen are essential. As with any prescription ophthalmic therapy, cyclosporine eye drops should only be used under the guidance of a qualified ophthalmologist, who can confirm suitability, monitor progress, and adjust care as needed.\n\nFrequently Asked Questions\n\n1. What are cyclosporine 0.05% eye drops used for?\nCyclosporine 0.05% eye drops are used to treat chronic dry eye disease caused by ocular surface inflammation. They help increase natural tear production in patients whose tear glands are suppressed due to inflammation, particularly when artificial tears alone aren't enough.\n\n2. How long can I use cyclosporine eye drops?\nCyclosporine eye drops are typically used long-term, as chronic dry eye is an ongoing condition. Many patients continue therapy for months to years under regular ophthalmologist supervision, since symptoms can return if the medication is stopped.\n\n3. Is Cyclomune a steroid?\nNo. Cyclomune (a brand of cyclosporine ophthalmic emulsion) is not a steroid. It is a calcineurin-inhibitor immunomodulator that works differently from steroid eye drops and does not carry the same risk of raised eye pressure or cataract associated with long-term steroid use.\n4. How quickly do cyclosporine eye drops start working?\nMost patients begin noticing improvement in tear production and dry eye symptoms within 6 to 12 weeks, though full benefit may take up to 3 to 6 months of consistent, twice-daily use.\n\n5. Can cyclosporine damage eyes?\nWhen used exactly as prescribed, cyclosporine eye drops are generally considered safe for long-term use. Temporary burning, stinging, or watering can occur at the time of instillation, but serious eye damage is uncommon. Any persistent pain, vision changes, or signs of infection should be reported to your ophthalmologist promptly.\n\n6. How much are cyclosporine 0.05% eye drops?\nPricing varies by brand, pack size, and region. Since this is a prescription-only medicine, please check current pricing with your prescribing doctor or a licensed pharmacy.\n\n7. Is cyclosporine a steroid?\nNo. Cyclosporine is a calcineurin inhibitor, a category of immunomodulating medication that is pharmacologically distinct from corticosteroids (steroids), even though both can reduce inflammation.\n\n8. Can I wear contact lenses while using cyclosporine eye drops?\nContact lenses should be removed before applying the drops and can typically be reinserted after about 15 minutes, unless your ophthalmologist gives different instructions.\n9. What happens if I stop using cyclosporine eye drops suddenly?\nStopping suddenly may cause dry eye symptoms to gradually return, since the underlying inflammation is no longer being managed. Always consult your doctor before discontinuing treatment.\n\n10. Can cyclosporine eye drops be used with artificial tears?\nYes, in many cases artificial tears can be used alongside cyclosporine drops for additional comfort, especially during the initial weeks before cyclosporine's full effect develops. Confirm timing and spacing with your doctor.\n\n11. Who should not use cyclosporine eye drops?\nPatients with known hypersensitivity to cyclosporine or its components, active untreated eye infections, or specific contraindications identified by their doctor should not use this medication without medical clearance.\n\n12. Are cyclosporine eye drops safe during pregnancy?\nUse during pregnancy or breastfeeding should only occur under medical supervision. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding before starting treatment.\n\n13. What is the difference between cyclosporine eye drops and lubricating eye drops?\nLubricating (artificial tear) drops provide temporary symptomatic relief by adding moisture to the eye, while cyclosporine drops target the underlying inflammation responsible for reduced natural tear production, offering a longer-term, disease-modifying approach.\n\n14. Can children use cyclosporine eye drops?\nUse in children should only be under the direct guidance and prescription of a pediatric ophthalmologist, based on individual clinical assessment.\n\n15. Do cyclosporine eye drops cause blurred vision?\nTemporary blurred vision can occur immediately after instillation in some patients. This usually resolves quickly. If blurred vision persists, consult your doctor.\n\n16. Can cyclosporine eye drops be used with other eye medications?\nOther eye medications, including other prescription drops, should only be combined with cyclosporine under your ophthalmologist's guidance, with appropriate spacing between different drops.\n\n17. Why do cyclosporine eye drops take so long to work?\nBecause cyclosporine works by gradually reducing chronic inflammation in the lacrimal gland and ocular surface rather than providing instant lubrication, visible improvement in natural tear production takes weeks to months rather than being immediate.", "price": 495.0, "discountamount": 149.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2468, "imageuri": "https://productimages.withfloats.com/actual/6a50922a464ced2a630398a1.png", "tileimageuri": "https://productimages.withfloats.com/tile/6a50922a464ced2a630398a1.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-07-10T06:33:12.096Z", "updatedon": "2026-07-10T06:33:12.096Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//cyclosporine-eye-drops-0-05-w-v/2468", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CIPVISION CYCLOPURE 0.5 mg", "category": "Opthalmology Range", "tags": [ "Cyclosporine Eye Drops 0.05% w/v", "cyclosporine eye drops", "cyclosporine eye drops uses", "cyclosporine eye drops ip 0.05 w/v", "cyclosporine eye drops price", "cyclosporine eye drops uses in hindi", "cyclosporine eye drops side effects", "cyclosporine eye drops 0.05", "cyclosporine eye drops brand name", "cyclosporine eye drops india" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69662101a96bbf383231d700", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "FABRICAL MG K₂7", "description": "FABRICAL MG K₂7 represents a scientifically advanced nutritional supplement that combines essential minerals and vitamins in a synergistic formulation designed to support optimal bone health, cardiovascular function, and overall metabolic wellness. This innovative product brings together six critical nutrients—Calcium Citrate Maleate, Magnesium Bisglycinate, Vitamin D3, Vitamin K2-7 (Menaquinone-7), Zinc, and Methylcobalamin—in precise therapeutic ratios that maximize bioavailability and clinical effectiveness.\nUnlike conventional calcium supplements that focus solely on calcium supplementation, FABRICAL MG K₂7 adopts a comprehensive, multi-nutrient approach that addresses the complex interplay between various micronutrients essential for skeletal integrity, neuromuscular function, immune competence, and metabolic regulation. This sophisticated formulation reflects current understanding of nutritional biochemistry, recognizing that optimal health outcomes require balanced supplementation rather than isolated nutrient provision.\nThe product has been meticulously formulated to address the growing epidemic of nutritional deficiencies affecting diverse populations, from elderly individuals experiencing age-related bone loss to young adults with suboptimal dietary intake, pregnant women with increased nutritional demands, and individuals with chronic conditions affecting nutrient absorption or utilization. FABRICAL MG K₂7 serves as a convenient, evidence-based solution for maintaining nutritional adequacy and supporting long-term health across various life stages.\nDetailed Understanding of FABRICAL MG K₂7 Components\nCalcium Citrate Maleate: Superior Calcium Bioavailability\nCalcium Citrate Maleate represents the premium form of calcium supplementation, offering significantly enhanced absorption compared to traditional calcium carbonate. This advanced calcium complex demonstrates approximately 25-30% better bioavailability, making it particularly valuable for individuals with reduced gastric acid production, including elderly populations and those taking proton pump inhibitors or H2-receptor antagonists. Unlike calcium carbonate, which requires acidic conditions for optimal dissolution, Calcium Citrate Maleate can be absorbed efficiently regardless of meal timing or stomach pH, providing greater flexibility and convenience.\nThe maleate component further enhances calcium absorption and utilization by supporting cellular energy metabolism and mitochondrial function. This sophisticated formulation ensures that supplemented calcium reaches target tissues—bones, teeth, muscles, and nerves—where it performs essential physiological functions rather than accumulating in soft tissues where it could potentially contribute to unwanted calcification.\nMagnesium Bisglycinate: The Gentle Magnesium Choice\nMagnesium Bisglycinate, also known as magnesium glycinate, stands as one of the most bioavailable and well-tolerated forms of magnesium supplementation. This chelated form, where magnesium is bound to two molecules of the amino acid glycine, offers exceptional absorption rates approaching 80-90% while minimizing the gastrointestinal side effects—particularly diarrhea—commonly associated with other magnesium forms like magnesium oxide or sulfate.\nMagnesium plays over 300 enzymatic roles throughout the body, making it indispensable for energy production, protein synthesis, muscle and nerve function, blood glucose control, and blood pressure regulation. Within FABRICAL MG K₂7, magnesium works synergistically with calcium, maintaining the critical calcium-magnesium balance essential for proper muscular contraction and relaxation, cardiovascular rhythm stability, and skeletal mineralization.\nVitamin D3: The Sunshine Vitamin in Its Active Form\nVitamin D3 (cholecalciferol) represents the most bioactive form of vitamin D, identical to what human skin synthesizes upon ultraviolet B exposure. This fat-soluble vitamin functions more accurately as a hormone, regulating calcium absorption from the intestines, maintaining serum calcium and phosphorus concentrations within optimal ranges, and modulating bone remodeling by both osteoblasts and osteoclasts.\nBeyond skeletal functions, Vitamin D3 exerts profound influences on immune system regulation, cellular differentiation and proliferation, neuromuscular function, and inflammation modulation. Vitamin D receptors exist throughout the body—in tissues ranging from the brain and heart to immune cells and muscle—highlighting its systemic importance. The inclusion of Vitamin D3 in FABRICAL MG K₂7 ensures that supplemented calcium can be effectively absorbed and utilized, preventing the futility of calcium supplementation in vitamin D-deficient states.\nVitamin K2-7: The Missing Link in Bone and Cardiovascular Health\nVitamin K2-7, specifically the menaquinone-7 (MK-7) form, represents perhaps the most revolutionary component of FABRICAL MG K₂7. This long-chain vitamin K2 demonstrates superior bioavailability and longer half-life compared to vitamin K1 (phylloquinone) found in green vegetables or shorter-chain K2 forms. Vitamin K2-7's critical function involves activating proteins responsible for proper calcium utilization—specifically matrix Gla protein (MGP) and osteocalcin.\nOsteocalcin, produced by bone-building osteoblasts, requires vitamin K2-dependent carboxylation to become active and effectively bind calcium into bone matrix, strengthening skeletal structure. Simultaneously, Vitamin K2-7 activates MGP, which prevents calcium deposition in arterial walls and soft tissues, directing calcium away from cardiovascular structures where it contributes to atherosclerosis and arterial stiffness. This dual action—promoting bone calcification while preventing vascular calcification—makes Vitamin K2-7 uniquely valuable, addressing the “calcium paradox” where individuals may simultaneously experience osteoporosis and arterial calcification.\nZinc: The Multifunctional Essential Mineral\nZinc, incorporated into FABRICAL MG K₂7 in highly bioavailable form, serves numerous critical physiological functions spanning immune competence, wound healing, protein synthesis, DNA synthesis, and cellular division. Regarding bone health specifically, zinc influences bone metabolism by supporting osteoblast activity and collagen synthesis, contributing to bone matrix formation and mineralization. Zinc also functions as a cofactor for alkaline phosphatase, an enzyme essential for bone mineralization.\nBeyond skeletal contributions, zinc supports immune system function, acting as a critical component of innumerable enzymes involved in immune cell development and function. Zinc deficiency impairs both innate and adaptive immunity, increasing susceptibility to infections. The mineral also supports sensory function (taste and smell), cognitive function, reproductive health, and skin integrity.\nMethylcobalamin: The Bioactive Vitamin B12\nMethylcobalamin represents the active, coenzyme form of vitamin B12, requiring no metabolic conversion to exert biological activity. This form demonstrates superior neurological benefits compared to cyanocobalamin, the synthetic form commonly used in supplements. Methylcobalamin directly participates in methionine synthesis and methylation reactions critical for nervous system health, DNA synthesis, red blood cell formation, and homocysteine metabolism.\nElevated homocysteine, resulting from inadequate B12 status, associates with increased cardiovascular disease risk, cognitive decline, and bone fragility. By supporting homocysteine conversion to methionine, methylcobalamin in FABRICAL MG K₂7 contributes to cardiovascular protection and potentially supports bone health through mechanisms independent of its well-established neurological and hematological roles.\nPrimary Uses and Clinical Applications of FABRICAL MG K₂7\nComprehensive Bone Health Support\nThe primary indication for FABRICAL MG K₂7 centers on comprehensive bone health support across various life stages and clinical scenarios. The formulation addresses all critical aspects of skeletal health: providing adequate calcium substrate for mineralization, ensuring calcium absorption through Vitamin D3, directing calcium into bone matrix via Vitamin K2-7, supporting bone matrix formation through magnesium and zinc, and protecting against homocysteine-related bone fragility through methylcobalamin.\nThis makes FABRICAL MG K₂7 particularly valuable for:\nOsteoporosis Prevention and Management: Postmenopausal women and elderly men experiencing age-related bone loss benefit from the formulation's comprehensive approach, potentially slowing bone density decline and reducing fracture risk.\nGrowing Children and Adolescents: During peak bone-building years, FABRICAL MG K₂7 supports optimal skeletal development, helping children and teenagers achieve maximum peak bone mass—a critical determinant of lifelong skeletal health.\nPregnancy and Lactation: Women during pregnancy and breastfeeding experience dramatically increased calcium demands. FABRICAL MG K₂7 helps prevent maternal bone density loss while supporting fetal skeletal development.\nCardiovascular Protection Through Proper Calcium Distribution\nThe Vitamin K2-7 component positions FABRICAL MG K₂7 as more than a bone health supplement—it's a cardiovascular protective formulation. By activating matrix Gla protein, the supplement helps prevent arterial calcification, potentially reducing cardiovascular disease risk. This dual benefit addresses the concerning observation that some individuals taking calcium supplements without adequate Vitamin K2 may experience increased cardiovascular events due to inappropriate calcium deposition in arterial walls.\nNeurological and Cognitive Support\nThe methylcobalamin component provides neurological support, particularly valuable for elderly individuals at risk for vitamin B12 deficiency due to reduced intrinsic factor production or those taking medications that impair B12 absorption (such as metformin or proton pump inhibitors). Adequate B12 status supports cognitive function, mood regulation, nerve conduction, and may help prevent peripheral neuropathy.\nImmune System Enhancement\nBoth zinc and vitamin D3 within FABRICAL MG K₂7 contribute significantly to immune competence. Vitamin D modulates both innate and adaptive immunity, while zinc supports immune cell development and function. This immune support proves particularly relevant during seasonal illness peaks or for individuals with compromised immunity.\nMuscle Function and Exercise Performance\nMagnesium's role in muscle contraction and relaxation, combined with calcium's involvement in excitation-contraction coupling, makes FABRICAL MG K₂7 valuable for athletes and physically active individuals. The formulation may help prevent exercise-associated muscle cramps, support recovery, and maintain electrolyte balance.\nKey Benefits of FABRICAL MG K₂7\nEnhanced Bioavailability and Absorption\nUnlike basic supplements using inferior ingredient forms, FABRICAL MG K₂7 utilizes premium, highly bioavailable compounds:\n\nCalcium Citrate Maleate offers superior absorption compared to calcium carbonate\nMagnesium Bisglycinate provides excellent absorption without gastrointestinal distress\nVitamin D3 is more potent than D2\nVitamin K2-7 (MK-7) has longer half-life and better tissue distribution than K1 or shorter-chain K2 forms\nMethylcobalamin is the active B12 form requiring no conversion\n\nThis superior bioavailability means lower doses can achieve therapeutic effects, reducing pill burden and potential adverse effects while maximizing benefits.\nSynergistic Nutrient Interactions\nFABRICAL MG K₂7's formulation recognizes that nutrients work together, not in isolation:\n\nVitamin D3 enhances calcium absorption while Vitamin K2-7 directs where that calcium goes\nMagnesium supports Vitamin D activation and calcium metabolism\nZinc supports bone matrix formation complementing calcium's role in mineralization\nMethylcobalamin supports methylation pathways that may influence bone health\n\nThis synergy delivers benefits exceeding what individual nutrients could provide separately.\nComprehensive Rather Than Fragmented Nutritional Support\nRather than requiring multiple separate supplements, FABRICAL MG K₂7 provides comprehensive support in a single, convenient formulation. This simplification improves compliance, reduces costs compared to purchasing individual supplements, and eliminates concerns about nutrient imbalances from uncoordinated supplementation.\nProtection Against the Calcium Paradox\nPerhaps the most significant benefit stems from the Vitamin K2-7 inclusion, which addresses the calcium paradox—simultaneously strengthening bones while protecting cardiovascular health by preventing arterial calcification. This represents a critical advancement over traditional calcium supplements that may inadvertently increase cardiovascular risk when taken without adequate Vitamin K2.\nSupport Across Multiple Physiological Systems\nBeyond bones, FABRICAL MG K₂7 benefits:\n\nCardiovascular System: Through arterial protection and homocysteine management\nNervous System: Via methylcobalamin's neurological support\nImmune System: Through vitamin D3 and zinc's immunomodulatory effects\nMuscular System: Via magnesium and calcium's roles in contraction\nMetabolic System: Through magnesium's involvement in glucose metabolism\n\nThis multi-system support delivers value far exceeding simple bone health supplementation.\nPotential Side Effects and Safety Considerations\nGenerally Well-Tolerated with Minimal Side Effects\nFABRICAL MG K₂7, when taken as directed, demonstrates excellent tolerability in most individuals. The selection of highly bioavailable, gentle nutrient forms specifically minimizes adverse effects common with inferior formulations.\nMild Gastrointestinal Effects\nSome users may initially experience mild digestive symptoms including:\n\nSlight nausea, particularly if taken on an empty stomach\nMinor bloating or gas\nMild constipation (though less likely than with calcium carbonate formulations)\n\nThese effects typically resolve within a few days as the body adjusts and can be minimized by taking the supplement with meals and ensuring adequate hydration.\nRare Allergic Reactions\nAlthough uncommon, some individuals may experience hypersensitivity to ingredients or excipients in the formulation. Signs include rash, itching, or swelling. Discontinuation and medical consultation are warranted if such reactions occur.\nConsiderations for Specific Populations\nIndividuals on Anticoagulants: Vitamin K2, while generally safer regarding coagulation than K1, may theoretically interact with warfarin. Patients on anticoagulation therapy should consult healthcare providers before starting FABRICAL MG K₂7, though recent evidence suggests K2 supplementation at consistent doses may not significantly affect INR stability.\nKidney Disease Patients: Individuals with chronic kidney disease should consult nephrologists before supplementing with calcium, magnesium, or vitamin D due to altered mineral metabolism and increased calcification risks in renal impairment.\nHypercalcemia Risk: Those with conditions predisposing to elevated calcium (hyperparathyroidism, sarcoidosis, certain cancers) should avoid supplementation without medical supervision.\nImportance of Appropriate Dosing\nExceeding recommended doses may increase adverse effect risks including:\n\nHypercalcemia (excessive calcium) causing nausea, constipation, kidney stones\nHypermagnesemia (excessive magnesium) causing diarrhea, cardiac abnormalities\nVitamin D toxicity (though requiring very high doses sustained over time)\n\nFollowing manufacturer's recommendations and consulting healthcare providers regarding individual needs ensures safe, effective use.\nRecommended Usage and Dosage Guidelines\nFABRICAL MG K₂7 should be taken according to manufacturer recommendations, typically one to two tablets daily with meals for optimal absorption of fat-soluble vitamins (D3 and K2-7). Taking the supplement with food containing some dietary fat further enhances absorption of these critical nutrients while minimizing potential gastrointestinal discomfort.\nConsistency in timing supports optimal benefits, as regular daily supplementation maintains stable nutrient levels. For individuals on multiple medications, spacing FABRICAL MG K₂7 administration at least two hours from certain medications (particularly thyroid hormones, bisphosphonates, or antibiotics) prevents potential absorption interference.\nIndividual requirements vary based on age, sex, dietary intake, health status, and specific deficiency risks. Healthcare provider consultation helps determine whether standard dosing suffices or whether adjustments are warranted. Periodic monitoring of vitamin D levels and other relevant biomarkers may be recommended to ensure supplementation achieves therapeutic goals without overshooting into excess.\nConclusion: FABRICAL MG K₂7 as a Comprehensive Nutritional Solution\nFABRICAL MG K₂7 stands as a sophisticated, scientifically formulated nutritional supplement that transcends traditional approaches to bone health support. By combining six synergistic nutrients in highly bioavailable forms, this innovative product addresses the complex, interconnected nature of skeletal health, cardiovascular protection, neurological function, and overall metabolic wellness.\nThe formulation's greatest strength lies in its comprehensive approach—recognizing that optimal health outcomes require balanced nutrition rather than isolated nutrient provision. The inclusion of Vitamin K2-7 particularly distinguishes FABRICAL MG K₂7 from conventional calcium supplements, addressing the critical calcium paradox and ensuring supplemented calcium strengthens bones while protecting cardiovascular structures.\nFor individuals seeking to support bone density, prevent osteoporosis, ensure adequate nutritional status during life stages of increased demand, or simply maintain optimal health through evidence-based supplementation, FABRICAL MG K₂7 offers a convenient, effective solution backed by nutritional science. Its excellent tolerability, superior ingredient quality, and multi-system benefits make it suitable for diverse populations from growing adolescents to active adults and elderly individuals concerned about age-related health challenges.\nAs with any nutritional supplement, FABRICAL MG K₂7 works best as part of a comprehensive health strategy including balanced nutrition, regular physical activity, adequate sleep, stress management, and appropriate medical care. It complements rather than replaces healthy lifestyle practices, providing nutritional insurance that helps fill gaps in modern diets while supporting long-term wellness.\nWhether you're proactively supporting your skeletal health, addressing identified nutritional deficiencies, or seeking comprehensive multi-nutrient support, FABRICAL MG K₂7 represents a premium choice that combines scientific sophistication with practical convenience, delivering measurable benefits that support vibrant health across all life stages.\n\nDisclaimer: This information is for educational purposes and does not constitute medical advice. Individual nutritional needs vary significantly based on numerous factors. Consult qualified healthcare professionals before starting any supplement regimen, particularly if you have existing health conditions, take medications, are pregnant or nursing, or have specific health concerns. Keep supplements out of reach of children and store according to manufacturer recommendations to maintain product integrity and safety.", "price": 250.0, "discountamount": 75.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2274, "imageuri": "https://productimages.withfloats.com/actual/696621081f531945cbd90a0c.png", "tileimageuri": "https://productimages.withfloats.com/tile/696621081f531945cbd90a0c.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-13T10:40:01.051Z", "updatedon": "2026-06-09T10:20:10.642Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//fabrical-mg-k-7/2274", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "FABRICAL MG K₂7", "category": "ORTHOLOGYRANG", "tags": [ "calcium citrate maleate magnesium bisglycinate tablets", "calcium citrate maleate with vitamin d3 k2 mk7", "magnesium bisglycinate with methylcobalamin tablets", "calcium citrate maleate vitamin k2-7 tablets", "best calcium citrate maleate tablets for bones", "magnesium bisglycinate tablets for muscle cramps", "methylcobalamin zinc tablets for nerve health", "calcium citrate maleate tablets for osteoporosis", "best calcium supplement with k2-7 for bone strength", "vitamin k2-7 mk7 with calcium benefits", "bone strength tablets with calcium magnesium zinc", "vitamin d3 k2 calcium tablets for elderly", "calcium citrate maleate tablets price in india", "best calcium magnesium vitamin d3 k2 tablets", "best bone health tablets with vitamin k2-7", "calcium magnesium zinc methylcobalamin tablets" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6960c83f3056ad8a5a1aecba", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Cinnarizine and Domperidone Tablets ", "description": "CLANARIZINE DOM represents an advanced pharmaceutical combination that brings together two potent therapeutic agents—Cinnarizine and Domperidone—in a single convenient tablet formulation. This innovative combination medication addresses multiple aspects of vestibular disorders, motion sickness, and associated nausea and vomiting, providing comprehensive relief for patients suffering from these debilitating conditions. Manufactured under stringent quality control standards, CLANARIZINE DOM offers a synergistic approach to managing symptoms that significantly impact quality of life and daily functioning.The combination of Cinnarizine and Domperidone in CLANARIZINE DOM is based on sound pharmacological principles. While Cinnarizine works primarily on the vestibular system to reduce dizziness and vertigo, Domperidone acts as an effective antiemetic to control nausea and vomiting. Together, these two active ingredients provide more comprehensive symptom control than either agent alone, making CLANARIZINE DOM an excellent choice for patients experiencing vestibular disturbances accompanied by gastrointestinal symptoms.This combination therapy is particularly valuable because vertigo, dizziness, and motion sickness are frequently accompanied by nausea and vomiting. Patients suffering from these conditions often find that addressing only one aspect of their symptoms provides insufficient relief. CLANARIZINE DOM's dual-action formula tackles both the underlying vestibular dysfunction and the accompanying gastrointestinal distress, offering patients a more complete therapeutic solution that improves both comfort and functional capacity.Understanding the Active IngredientsCinnarizine is a calcium channel blocker with specific antihistaminic and vestibular suppressant properties. Unlike systemic calcium channel blockers used for cardiovascular conditions, Cinnarizine selectively acts on the blood vessels in the inner ear and brain, improving blood flow to these areas. This enhanced circulation helps reduce the frequency and severity of vertigo attacks while also preventing motion sickness. Cinnarizine also possesses mild antihistaminic effects that contribute to its anti-nausea properties, though this is not its primary mechanism of action.The medication works by blocking calcium channels in the vestibular system, which helps stabilize the sensory organs responsible for balance. By reducing the excessive stimulation of the vestibular apparatus, Cinnarizine decreases the sensation of spinning or imbalance that characterizes vertigo. Additionally, its vasodilatory effects improve microcirculation in the inner ear, which can be beneficial for conditions where reduced blood flow contributes to symptoms.Domperidone is a peripheral dopamine antagonist that acts primarily as a prokinetic and antiemetic agent. Unlike some antiemetic medications that cross the blood-brain barrier and cause sedation or extrapyramidal side effects, Domperidone works predominantly in the peripheral nervous system. It blocks dopamine receptors in the chemoreceptor trigger zone (CTZ) located outside the blood-brain barrier, effectively preventing nausea and vomiting without causing significant central nervous system effects.Domperidone also enhances gastrointestinal motility by promoting coordinated contractions of the stomach and upper small intestine. This prokinetic effect helps empty the stomach more efficiently, reducing feelings of fullness, bloating, and discomfort that often accompany vestibular disorders. By accelerating gastric emptying, Domperidone also reduces the likelihood of gastroesophageal reflux, which can exacerbate nausea in some patients.The combination of these two medications in CLANARIZINE DOM creates a complementary therapeutic effect. While Cinnarizine addresses the vestibular component of dizziness and vertigo, Domperidone manages the gastrointestinal symptoms that frequently accompany these conditions. This dual approach provides more comprehensive symptom relief and improves overall treatment outcomes compared to monotherapy with either agent alone.Clinical Applications and UsesCLANARIZINE DOM is indicated for a wide range of conditions characterized by vertigo, dizziness, and associated nausea. Understanding these clinical applications helps healthcare providers select appropriate candidates for this combination therapy.Vestibular Disorders: The primary indication for CLANARIZINE DOM includes various vestibular disorders that cause vertigo and imbalance. These conditions include Ménière's disease, benign paroxysmal positional vertigo (BPPV), vestibular neuritis, and labyrinthitis. Patients with these disorders experience episodes of spinning sensation, loss of balance, and often severe nausea. CLANARIZINE DOM helps reduce the frequency and intensity of vertigo attacks while controlling the accompanying gastrointestinal symptoms.Motion Sickness: CLANARIZINE DOM is highly effective for preventing and treating motion sickness, whether related to travel by car, boat, airplane, or amusement park rides. The medication can be taken prophylactically before travel or at the onset of symptoms. The combination is particularly useful for individuals who experience severe nausea and vomiting with motion sickness, as Domperidone provides powerful antiemetic effects that complement Cinnarizine's anti-motion-sickness properties.Migraine-Associated Vertigo: Many patients with migraines experience vestibular symptoms, including dizziness, vertigo, and motion sensitivity, either during migraine attacks or as independent episodes. CLANARIZINE DOM can help manage these vestibular manifestations of migraine, reducing both the vertigo and the nausea that often accompany migraine headaches.Post-Concussion Syndrome: Following head injuries, some patients develop persistent dizziness, balance problems, and nausea as part of post-concussion syndrome. CLANARIZINE DOM may provide symptomatic relief for these patients during their recovery period, though it should be used as part of a comprehensive treatment approach that includes rest, gradual return to activities, and vestibular rehabilitation when appropriate.Cerebrovascular Insufficiency: In older adults with reduced blood flow to the brain, symptoms such as dizziness, vertigo, tinnitus (ringing in the ears), and cognitive difficulties may develop. Cinnarizine's vasodilatory properties can improve cerebral circulation, potentially reducing these symptoms. The addition of Domperidone helps manage any associated nausea.Radiation-Induced or Chemotherapy-Induced Nausea: While not a primary indication, some healthcare providers use CLANARIZINE DOM as adjunctive therapy for patients undergoing cancer treatment who experience both nausea and dizziness. Domperidone's strong antiemetic properties are particularly valuable in this context.Key Benefits of CLANARIZINE DOMThe unique combination of Cinnarizine and Domperidone in CLANARIZINE DOM offers numerous advantages that make it a preferred choice for managing vestibular disorders and associated symptoms.Comprehensive Symptom Control: The primary benefit of CLANARIZINE DOM is its ability to address multiple symptoms simultaneously. Rather than requiring patients to take separate medications for vertigo and nausea, this combination provides unified treatment in a single tablet. This comprehensive approach improves symptom control across the full spectrum of vestibular disorder manifestations, from the spinning sensation to the gastrointestinal distress that often accompanies it.Improved Patient Compliance: Taking multiple medications can be burdensome, particularly for patients who feel dizzy or nauseated. CLANARIZINE DOM simplifies the treatment regimen by combining two medications in one tablet, making it easier for patients to adhere to their prescribed therapy. Better compliance translates to better outcomes, as consistent medication use is essential for managing chronic vestibular conditions.Synergistic Therapeutic Effects: The combination of Cinnarizine and Domperidone creates synergistic effects that enhance overall efficacy. While Cinnarizine reduces vestibular stimulation and improves inner ear blood flow, Domperidone prevents nausea and promotes gastric emptying. This dual action addresses both the cause and consequences of vestibular dysfunction, providing more complete relief than either medication alone.Reduced Central Nervous System Side Effects: Because Domperidone works primarily in the peripheral nervous system rather than crossing the blood-brain barrier extensively, CLANARIZINE DOM causes less sedation and fewer cognitive effects compared to some alternative antiemetic medications. This allows patients to maintain better alertness and function during treatment, which is particularly important for those who need to continue working or performing daily activities.Enhanced Quality of Life: Vertigo and chronic dizziness significantly impair quality of life, limiting mobility, social interactions, and occupational functioning. The nausea and vomiting that accompany these conditions add another layer of disability. By effectively controlling both vestibular and gastrointestinal symptoms, CLANARIZINE DOM helps restore patients' ability to engage in normal activities, improving overall life satisfaction and functional independence.Fast Onset of Action: CLANARIZINE DOM provides relatively rapid symptom relief, with many patients experiencing improvement within 30 minutes to 2 hours after taking the medication. This quick onset is particularly valuable for acute episodes of vertigo or when taking the medication prophylactically before situations that might trigger motion sickness.Suitable for Long-Term Use: For patients with chronic vestibular disorders requiring ongoing treatment, CLANARIZINE DOM is generally safe for extended use when properly monitored by a healthcare provider. The medication maintains its effectiveness over time without significant tolerance development, making it suitable for long-term symptom management.Improved Gastric Emptying: The prokinetic effects of Domperidone benefit not only nausea but also other gastrointestinal symptoms such as early satiety, bloating, and upper abdominal discomfort. Patients with vestibular disorders often develop gastroparesis or delayed gastric emptying secondary to their condition, and Domperidone addresses this issue effectively.Vascular Benefits: Cinnarizine's ability to improve blood flow to the inner ear and brain provides additional benefits beyond symptom control. Enhanced microcirculation may support healing and recovery in conditions where vascular insufficiency contributes to vestibular dysfunction.Side Effects and Safety ConsiderationsLike all medications, CLANARIZINE DOM can cause side effects, though not everyone experiences them. Understanding potential adverse effects helps patients recognize when to seek medical attention and allows healthcare providers to monitor therapy appropriately.Common Side Effects:The most frequently reported side effect of CLANARIZINE DOM is drowsiness or sedation, occurring in approximately 10-20% of patients. This effect is primarily attributable to Cinnarizine's antihistaminic properties. Patients should avoid driving or operating machinery until they know how the medication affects them. Taking the medication at bedtime can minimize daytime drowsiness for some patients.Dry mouth is another common side effect, affecting roughly 10-15% of patients. This occurs due to anticholinergic effects and can be managed by sipping water frequently, chewing sugar-free gum, or using saliva substitutes if severe. Maintaining good oral hygiene is important to prevent dental problems associated with reduced saliva production.Mild gastrointestinal symptoms, including constipation, abdominal discomfort, or changes in bowel habits, may occur. While Domperidone promotes gastric emptying, it can occasionally alter bowel motility. These effects are usually mild and resolve with continued use or dose adjustment.", "price": 55.0, "discountamount": 17.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2271, "imageuri": "https://productimages.withfloats.com/actual/6960c8410b0da405bc908e58.png", "tileimageuri": "https://productimages.withfloats.com/tile/6960c8410b0da405bc908e58.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-09T09:19:59.281Z", "updatedon": "2026-03-12T09:24:10.244Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//cinnarizine-and-domperidone-tablets-/2271", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CLANARIZINE DOM", "category": "NEUROLOGY RANGE", "tags": [ "cinnarizine and domperidone tablet uses", "what is cinnarizine & domperidone tablet used for", "cinnarizine domperidone combination medicine benefits", "how cinnarizine domperidone tablet works", "cinnarizine domperidone tablet for vertigo treatment", "cinnarizine domperidone tablet for inner ear problem", "cinnarizine domperidone tablet for balance disorder", "cinnarizine domperidone tablet for travel sickness", "cinnarizine domperidone tablet for gastric nausea", "cinnarizine & domperidone tablet price in india", "cinnarizine domperidone tablet brand name", "cinnarizine domperidone tablet manufacturer in india" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6958dbfa1063d98b1e8f2fe1", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Benidipine 4mg", "description": "BENIPRIME 4, containing Benidipine 4 mg, offers effective management for high blood pressure and related heart conditions. This calcium channel blocker helps relax blood vessels to improve blood flow and reduce strain on the heart. Patients often find it reliable for daily control of hypertension symptoms.\n\nWhat is BENIPRIME 4?\nBENIPRIME 4 is a branded tablet from Steris Healthcare Pvt Ltd, featuring 4 mg of Benidipine as the active ingredient. Benidipine belongs to the dihydropyridine class of calcium channel blockers, designed specifically for cardiovascular health. Each tablet delivers a precise dose in a user-friendly form, typically packaged in strips of 10 for convenient use. Manufactured under strict quality standards, it targets essential needs in hypertension care, making it a staple in many treatment plans across India.\n​\n\nThis medication stands out due to its triple action on L-type, N-type, and T-type calcium channels, providing broader vascular protection compared to some other blockers. Doctors prescribe it for adults dealing with persistent high blood pressure or chest pain, often starting at this 4 mg strength for balanced efficacy. Unlike generic options, BENIPRIME 4 ensures consistent absorption and formulation tailored for Indian patients, with pricing around Rs 62-89 per strip after discounts.\n​\n\nHow BENIPRIME 4 Works\nBenidipine in BENIPRIME 4 blocks calcium entry into smooth muscle cells of blood vessels and heart muscles. This action causes vasodilation, widening arteries to lower resistance and ease blood flow. By reducing systolic and diastolic pressure, it lightens the heart's workload without drastically slowing the heartbeat.\n​\n\nThe unique blockade of multiple calcium channels also boosts nitric oxide production, offering antioxidant effects and protection against artery hardening. This sustained mechanism provides 24-hour control, ideal for once-daily dosing after breakfast. Over time, it may even reduce urinary protein and triglycerides, supporting kidney and metabolic health in hypertensives.\n​\n\nKey Uses of BENIPRIME 4\nBENIPRIME 4 primarily treats essential hypertension, helping prevent strokes, heart attacks, and kidney damage. It effectively manages angina pectoris by enhancing coronary blood supply, reducing chest pain episodes during activity.\n​\n\nPhysicians also use it for renal parenchymal hypertension, where kidney issues elevate blood pressure. In emergencies like hypertensive crises or subarachnoid hemorrhage, higher doses prove beneficial, though 4mg serves as maintenance. For arrhythmia or anal fissures linked to vascular strain, it offers supportive relief.\n​\n\nLowers high blood pressure in adults, including severe cases with dose adjustments.\n​\n\nEases angina symptoms, improving exercise tolerance and daily life quality.\n​\n\nProtects renal function in proteinuric patients by stabilizing vessels.\n​\n\nDosage and Administration\nTake BENIPRIME 4 as 4 mg once daily, swallowed whole after a meal to minimize stomach upset. Doctors may adjust to 2-8mg based on response, age, or kidney/liver status, never exceeding 8 mg daily without monitoring. Consistency in timing ensures steady levels for optimal pressure control.\n​\n\nMissed doses require prompt intake if remembered soon, but skip if near the next one—avoid doubles. Pair with lifestyle changes like low-salt diets and exercise for best results. Always consult for personalization, especially in elderly or comorbid patients.\n​\n\nKey Benefits\nBENIPRIME 4 excels in long-term blood pressure reduction, with studies showing sustained drops in brachial-ankle pulse wave velocity beyond mere pressure effects. It protects the heart and kidneys through anti-sclerotic and antioxidant actions, lowering cardiovascular event risks.\n​\n\nPatients experience fewer angina attacks, better endurance, and improved quality of life. The once-daily regimen boosts adherence, while vascular selectivity minimizes reflex tachycardia common in other blockers. Clinical data indicate reduced C-reactive protein and aldosterone, curbing inflammation and fibrosis.\n​\n\nBenefit\tDescription\tSupporting Evidence\nBP Control\tReduces systolic/diastolic pressure effectively over 24 hours \n​\tLong-term studies show persistent effects post-treatment \n​\nHeart Protection\tImproves coronary flow, cuts angina frequency \n​\tMyocardial protection via NO stimulation \n​\nRenal Support\tLowers proteinuria, aids kidney hypertension \n​\tAnti-oxidative vascular benefits \n​\nAdherence Ease\tOnce-daily dosing with sustained release \n​\tHigh membrane affinity for lasting action \n​\nAdditional perks include potential triglyceride reduction and osteoblast stimulation for bone health in hypertensives.\n\nPotential Side Effects\nMost users tolerate BENIPRIME 4 well, with mild, transient effects resolving spontaneously. Common issues include headache, dizziness, flushing, ankle swelling, palpitations, fatigue, nausea, and sleepiness.\n​\n\nLess frequent are constipation, abdominal pain, tinnitus, shoulder stiffness, urinary frequency, or elevated liver enzymes. Rare serious reactions involve severe hypotension, rash, itching, or allergic responses—seek immediate care if these arise. Monitor blood pressure during initiation to avoid drops.\n\nHeart-related: Palpitations, chest pressure\n​\n\nNervous system: Dizziness, headache\n\nSkin/Vascular: Flushing, edema.\n\nGI: Nausea, constipation\n​\n\nLiver/kidney patients need caution; inform doctors of history.\n\n\nPrecautions and Interactions\nAvoid in hypotension, severe aortic stenosis, or hypersensitivity to dihydropyridines. Use cautiously in liver/kidney impairment, pregnancy, or breastfeeding—benefits must outweigh risks. Grapefruit juice may amplify effects; limit alcohol.\n​\n\nIt interacts with beta-blockers, digoxin, or CYP3A4 inhibitors like ketoconazole, potentially enhancing hypotension. Regular monitoring of BP, electrolytes, and renal function is advised during therapy. Abrupt stop may rebound pressure; taper under guidance.\n​\nConclusion\nBENIPRIME 4 with Benidipine 4 mg empowers reliable hypertension and angina control through innovative calcium channel action. Balancing potent benefits like organ protection and ease of use against manageable side effects, it fits seamlessly into modern cardiac care. Consult healthcare providers for tailored integration with lifestyle for lasting heart health. ", "price": 89.0, "discountamount": 27.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2261, "imageuri": "https://productimages.withfloats.com/actual/6958dbfc615a7d157715572f.jpg", "tileimageuri": "https://productimages.withfloats.com/tile/6958dbfc615a7d157715572f.jpg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-03T09:06:02.841Z", "updatedon": "2026-03-13T06:54:02.808Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//benidipine-4mg/2261", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "BENIPRIME 4", "category": "CARDIOLOGYRANGE", "tags": [ "benidipine 4mg", "benidipine 4mg tab", "benidipine hydrochloride uses.", "benidipine.", "benidipine 4 mg", "benidipine 4", "benidipine maximum dose", "benidipine 4 mg uses.", "benidipine price" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "694d14f6274fc8b97e9b7120", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Mirtazapine 30mg", "description": "MIRTAZPRIME 30 is a pharmaceutical formulation containing Mirtazapine 30mg as per Indian Pharmacopoeia (IP) standards. This prescription medication belongs to a class of drugs known as tetracyclic antidepressants and represents an advanced therapeutic option for individuals struggling with major depressive disorder and related mental health conditions. Manufactured under stringent quality control measures, MIRTAZPRIME 30 offers patients a reliable and effective solution for managing depression while also addressing associated symptoms such as insomnia and anxiety.\nMirtazapine, the active pharmaceutical ingredient in MIRTAZPRIME 30, works through a unique dual mechanism that distinguishes it from other antidepressants. Unlike selective serotonin reuptake inhibitors (SSRIs), mirtazapine enhances the release of both norepinephrine and serotonin in the brain by blocking specific receptors. This innovative approach not only helps alleviate depressive symptoms but also provides sedative effects that can be particularly beneficial for patients experiencing sleep disturbances alongside depression.\nTherapeutic Uses and Applications\nMIRTAZPRIME 30 is primarily indicated for the treatment of major depressive disorder (MDD), a serious mental health condition characterized by persistent feelings of sadness, hopelessness, and loss of interest in daily activities. The medication has demonstrated significant efficacy in clinical trials, showing improvement in mood, energy levels, and overall quality of life for patients suffering from depression.\nBeyond its primary indication, healthcare providers may prescribe MIRTAZPRIME 30 for various off-label uses based on clinical judgment and patient needs. The medication has shown promise in managing generalized anxiety disorder, where excessive worry and tension interfere with daily functioning. Its sedative properties make it particularly valuable for patients experiencing insomnia related to depression or anxiety, as it can help restore healthy sleep patterns without the need for additional sleep medications.\nThe 30mg dosage strength represents a therapeutic level commonly prescribed for maintenance treatment after initial dose titration. Patients typically begin with lower doses and gradually increase to 30mg as their body adjusts to the medication and their symptoms require more robust management. This dosage provides an optimal balance between therapeutic efficacy and side effect management for many individuals.\nMIRTAZPRIME 30 may also be considered for patients who have not responded adequately to other antidepressant therapies, offering an alternative mechanism of action that can break through treatment-resistant depression. Additionally, its appetite-stimulating effects can be beneficial for patients experiencing significant weight loss due to depression or other medical conditions.\nKey Benefits and Therapeutic Advantages\nThe benefits of MIRTAZPRIME 30 extend beyond simple symptom relief, offering patients a multifaceted approach to mental health recovery. One of the most significant advantages is its relatively rapid onset of action compared to many other antidepressants. While most SSRIs require several weeks to demonstrate meaningful clinical improvement, patients taking mirtazapine often experience some relief from symptoms within one to two weeks, with continued improvement over subsequent weeks.\nThe dual neurotransmitter action of MIRTAZPRIME 30 provides comprehensive coverage of depressive symptoms. By enhancing both serotonergic and noradrenergic neurotransmission, the medication addresses the complex neurochemical imbalances underlying depression more thoroughly than single-mechanism antidepressants. This broader action can result in more complete symptom resolution and better overall outcomes.\nSleep improvement represents another crucial benefit of MIRTAZPRIME 30. The medication's sedative properties, particularly pronounced at lower doses, help patients fall asleep faster and enjoy more restorative sleep throughout the night. This is especially valuable since sleep disturbances are both a symptom and an exacerbating factor in depression. Better sleep quality contributes to improved daytime functioning, energy levels, and emotional regulation.\nUnlike many antidepressants that commonly cause sexual dysfunction, MIRTAZPRIME 30 has a relatively favorable profile in this regard. The medication is less likely to interfere with sexual function, making it an attractive option for patients who have experienced these troublesome side effects with other antidepressants. This characteristic can significantly improve treatment adherence and quality of life.\nThe appetite-stimulating effect, while considered a side effect by some, can be therapeutically beneficial for patients experiencing significant weight loss or poor appetite due to depression. MIRTAZPRIME 30 can help restore healthy eating patterns and reverse the physical decline that often accompanies severe depressive episodes.\nFurthermore, MIRTAZPRIME 30 does not typically cause the gastrointestinal side effects commonly associated with SSRI antidepressants, such as nausea, diarrhea, or stomach upset. This improved gastrointestinal tolerability enhances patient comfort and compliance with treatment regimens.\nPotential Side Effects and Safety Considerations\nWhile MIRTAZPRIME 30 offers numerous therapeutic benefits, patients should be aware of potential side effects that may occur during treatment. Understanding these effects helps patients make informed decisions and enables early identification of any concerning symptoms requiring medical attention.\nThe most commonly reported side effect is drowsiness or sedation, particularly during the initial weeks of treatment. This effect is typically most pronounced during the first few hours after taking the medication, which is why it's generally recommended for evening administration. Patients should exercise caution when driving, operating machinery, or engaging in activities requiring alertness until they understand how the medication affects them personally.\nIncreased appetite and weight gain represent another frequent side effect of MIRTAZPRIME 30. While beneficial for some patients, others may find this effect undesirable. Weight gain typically ranges from moderate to significant and appears to be dose-related. Patients concerned about weight should discuss dietary strategies and exercise plans with their healthcare provider.\nDry mouth is a common anticholinergic side effect that can cause discomfort but is generally manageable through increased fluid intake, sugar-free gum or candy, and good oral hygiene practices. Some patients may also experience dizziness, particularly when standing up quickly, due to the medication's effects on blood pressure regulation.\nConstipation may occur in some patients and can usually be managed through dietary modifications, increased fiber intake, adequate hydration, and regular physical activity. Less commonly, patients might experience confusion, abnormal dreams, or changes in thinking, particularly in older adults who may be more sensitive to the medication's effects.\nSerious side effects, while rare, require immediate medical attention. These include signs of allergic reactions such as rash, itching, swelling, severe dizziness, or difficulty breathing. Agranulocytosis, a dangerous decrease in white blood cells, is an extremely rare but serious complication that manifests as fever, sore throat, or signs of infection. Any unexplained fever or signs of infection should prompt immediate contact with a healthcare provider.\nSerotonin syndrome is another rare but potentially life-threatening condition that can occur when mirtazapine is combined with other medications affecting serotonin levels. Symptoms include agitation, hallucinations, rapid heartbeat, fever, excessive sweating, muscle stiffness, or coordination problems. Patients should inform their healthcare provider about all medications and supplements they are taking to avoid dangerous interactions.\nAbrupt discontinuation of MIRTAZPRIME 30 can lead to withdrawal symptoms, including nausea, anxiety, irritability, and flu-like symptoms. Therefore, any decision to stop the medication should be made in consultation with a healthcare provider who can develop an appropriate tapering schedule.\nImportant Usage Guidelines\nMIRTAZPRIME 30 should always be taken exactly as prescribed by a qualified healthcare professional. The medication is typically administered once daily, preferably in the evening before bedtime due to its sedative effects. Tablets should be swallowed whole with water and can be taken with or without food, though taking them with food may help reduce any stomach upset.\nConsistency in timing is important for maintaining stable blood levels of the medication and optimizing therapeutic effects. Patients should try to take their dose at approximately the same time each evening. If a dose is missed, it should be taken as soon as remembered unless it's close to the time for the next scheduled dose, in which case the missed dose should be skipped rather than doubling up.\nThe full therapeutic benefits of MIRTAZPRIME 30 may take several weeks to manifest. Patients should continue taking the medication as prescribed even if they don't feel immediate improvement. Premature discontinuation is a common reason for treatment failure in depression management.\nRegular follow-up appointments with the prescribing physician are essential for monitoring treatment response, adjusting dosages if necessary, and screening for potential side effects. Patients should maintain open communication with their healthcare team about their symptoms, concerns, and any changes in their condition.\nConclusion\nMIRTAZPRIME 30 represents a valuable therapeutic option in the comprehensive management of major depressive disorder and related conditions. Its unique mechanism of action, combining enhanced noradrenergic and serotonergic neurotransmission with sedative and appetite-stimulating properties, offers distinct advantages for carefully selected patients. The medication's ability to improve both mood symptoms and sleep disturbances makes it particularly useful for patients experiencing depression accompanied by insomnia.\nThe relatively favorable side effect profile, particularly regarding sexual function and gastrointestinal tolerability, enhances patient acceptance and adherence to treatment. While potential side effects such as sedation, increased appetite, and weight gain require monitoring and management, many patients find these effects tolerable compared to the debilitating symptoms of untreated depression.\nSuccess with MIRTAZPRIME 30, as with any antidepressant therapy, depends on proper patient selection, appropriate dosing, regular monitoring, and a comprehensive treatment approach that may include psychotherapy, lifestyle modifications, and social support alongside pharmacological intervention. Patients should work closely with their healthcare providers to optimize treatment outcomes and maintain long-term mental health wellness.\nThe decision to use MIRTAZPRIME 30 should always be made collaboratively between patient and physician, considering individual symptoms, treatment history, coexisting medical conditions, and personal preferences. With proper use under medical supervision, MIRTAZPRIME 30 can be an effective tool in helping patients reclaim their lives from the devastating effects of depression and move toward recovery and renewed well-being.", "price": 262.0, "discountamount": 79.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2254, "imageuri": "https://productimages.withfloats.com/actual/694d14f83d39ca31a28d046b.png", "tileimageuri": "https://productimages.withfloats.com/tile/694d14f83d39ca31a28d046b.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-25T10:41:58.966Z", "updatedon": "2026-03-13T07:46:51.004Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//mirtazapine-30mg/2254", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MIRTAZPRIME 30", "category": "NEUROLOGYRANGE", "tags": [ "MIRTAZPRIME 30", "Mirtazapine 30mg as per Indian Pharmacopoeia (IP) standards", "managing depression", "insomnia and anxiety.", "depression or anxiety.", "depredepressive episodes.", "helping patients reclaim their lives from the devastating effects of depression." ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "693c0c9c0c30ac5c9f8203b4", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Isosorbide Mononitrate IP 30mg Tablets", "description": "CARDULES ISMN SR 30 tablets provide sustained-release Isosorbide Mononitrate IP 30mg, a nitrate medication designed for long-term management of angina in patients with coronary artery disease. This formulation from Steris Healthcare Pvt Ltd ensures steady vasodilation to improve heart blood flow and reduce chest pain episodes. It supports daily activities by minimizing oxygen demand on the heart muscle.​\nProduct Overview\nCARDULES ISMN SR 30 contains Isosorbide Mononitrate IP 30mg in a sustained-release matrix, allowing once-daily dosing for consistent therapeutic levels over 12-24 hours. The tablet's extended-release technology prevents peak-trough fluctuations common in immediate-release forms, promoting better patient compliance. Each film-coated tablet delivers precise bioavailability, with the active metabolite nitric oxide activating guanylate cyclase to boost cyclic GMP, relaxing vascular smooth muscle primarily in veins.​\n\nThis mechanism reduces preload (venous return to the heart) and afterload (arterial resistance), easing cardiac workload without significantly affecting heart rate. Unlike short-acting nitrates for acute relief, CARDULES ISMN SR 30 targets prophylaxis in chronic stable angina, often prescribed alongside beta-blockers or calcium channel blockers. Available in strips of 10 tablets, it undergoes rigorous quality testing at Steris facilities to meet IP standards, ensuring purity and stability.​\n\nKey Uses\nCARDULES ISMN SR 30 primarily prevents angina pectoris in coronary artery disease, where narrowed vessels limit oxygen supply during exertion. Patients experience fewer chest pain attacks during walking, climbing stairs, or stress.​\n\nIt manages chronic stable angina by enhancing myocardial perfusion, suitable for long-term therapy in adults over 18. Healthcare providers may use it adjunctively for coronary spasm or post-myocardial infarction prophylaxis to stabilize symptoms.​\n\nIn select cases, it aids heart failure management by offloading the heart, though not as monotherapy. Always initiate under cardiology supervision with dose titration to tolerance.​\n\nMajor Benefits\nThe sustained-release profile offers 24-hour protection with single morning dosing, improving adherence and lifestyle quality for active patients. It boosts exercise tolerance by 20-30% in trials, allowing longer physical efforts without angina onset.​\n\nBy dilating vessels, it decreases ischemia risk, potentially lowering hospitalization rates for acute episodes. Compared to placebo, users report halved attack frequency within weeks, enhancing daily productivity and emotional well-being.​\n\nBenefit\tMechanism\tPatient Outcome\nAngina Prevention\tVasodilation reduces preload/afterload ​\tFewer attacks, better exertion capacity\nSteady Relief\tSR formulation maintains levels ​\tOnce-daily convenience, no fluctuations\nHeart Protection\tImproves O2 delivery ​\tReduced ischemia, enhanced QoL\nCompliance Boost\tSimple regimen ​\tHigher adherence vs multiple doses\nAdditional perks include minimal impact on blood pressure in normotensives and compatibility with anti-anginals, making it versatile in combo therapy.\n\nPotential Side Effects\nCommon effects include headache (dose-related, often transient in first week), dizziness, or flushing due to vasodilation—hydrate and rise slowly to manage. Gastrointestinal upset like nausea occurs in 5-10% initially.​\n\nOrthostatic hypotension risks fainting, especially early; avoid alcohol or other vasodilators. Rare serious issues encompass severe hypotension, tachycardia, or methemoglobinemia with overdose—monitor blood pressure regularly.​\n\nAllergic reactions (rash, itching) or vision changes warrant discontinuation. Contraindicated in hypotension, glaucoma, or recent PDE5 inhibitor use; caution in anemia or hypothyroidism.​\n\nDosage Guidelines\nStart with 30mg once daily upon waking, swallowed whole without crushing. Titrate to 60mg if tolerated after 3-7 days, max 120mg/day. Take on empty stomach for optimal absorption; avoid late dosing to prevent nocturnal headaches.​\n\nAdjust for elderly or renal/hepatic impairment. Tolerance may develop—nitrate-free interval (evening) helps sustain efficacy. Store below 30°C.​\nConclusion\nCARDULES ISMN SR 30 empowers angina patients with reliable, once-daily prevention, restoring confidence in routine activities under Steris Healthcare's quality assurance. Its targeted vasodilation balances efficacy and tolerability for sustained heart health", "price": 65.0, "discountamount": 19.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2243, "imageuri": "https://productimages.withfloats.com/actual/693c0ca6391a3fa44b0608d8.png", "tileimageuri": "https://productimages.withfloats.com/tile/693c0ca6391a3fa44b0608d8.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-12T12:37:48.92Z", "updatedon": "2026-03-14T08:21:58.091Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//isosorbide-mononitrate-ip-30mg-tablets/2243", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CARDULES ISMN SR 30", "category": "", "tags": [ "Isosorbide Mononitrate IP 30mg Tablets", "coronary artery disease", "heart blood flow and reduce chest pain episodes", "oxygen demand on the heart muscle", "relaxing vascular smooth muscle primarily in veins" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false } ], "hasmoreitems": false, "isapirequest": false, "totalresults": 27, "query": null, "floatingpoint": null }