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{ "products": [ { "_id": "6a7722af7f45a0190eb37920", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Tolperisone Hydrochloride & Paracetamol Tablets", "description": "TOPERITIME P 150/325: Dual-Action Relief for Musculoskeletal Pain and Spasms\nTOPERITIME P 150/325 is a prescription combination therapy formulated to treat acute musculoskeletal discomfort, muscle stiffness, and associated inflammatory pain. By uniting a centrally acting muscle relaxant with a proven analgesic, this film-coated tablet addresses both the neurological and physical aspects of muscle strain, restoring movement and facilitating recovery.\n\nActive Ingredients\nEach film-coated tablet contains:\n\nTolperisone Hydrochloride (150 mg): A muscle relaxant targeting involuntary contractions within the central nervous system.\n\nParacetamol (325 mg): A widely recognized analgesic and antipyretic agent that blocks pain signal transmission.\n\nAvailable in blister packaging and dispensed strictly under a licensed physician's order.\n\nTherapeutic Mechanism\nPainful muscle conditions often create a feedback loop where localized pain triggers involuntary spasms, which in turn exacerbate the pain. TOPERITIME P 150/325 disrupts this cycle through a two-pronged mechanism:\n\nNeuromuscular Regulation: Tolperisone Hydrochloride acts on the spinal cord and brainstem reflexes to inhibit hyperactive nerve impulses driving muscle tension. Unlike traditional skeletal muscle relaxants, it achieves this with minimal central nervous system depression, significantly reducing the likelihood of heavy sedation.\n\nNociceptive Blocking: Paracetamol inhibits prostaglandin synthesis within the central nervous system, raising the body's overall pain threshold and attenuating pain signals originating from injured tissues.\n\nBy simultaneously relaxing tight muscle fibers and dampening pain sensation, the formulation provides comprehensive symptomatic relief.\n\nClinical Indications\nHealthcare professionals may prescribe TOPERITIME P 150/325 for various acute and subacute conditions characterized by pain and hypertonia, including:\n\nAcute muscle spasms and athletic injuries\n\nAcute or chronic lower back pain (lumbago)\n\nCervical spine discomfort and stiff neck\n\nCervical and lumbar spondylosis\n\nFrozen shoulder (adhesive capsulitis)\n\nPost-operative or post-traumatic muscle recovery\n\nGeneralized connective tissue or orthopedic pain\n\nKey Clinical Features\nBalanced Dual Action: Simultaneously targets involuntary contractions and pain sensation.\n\nLow-Sedation Profile: Tolperisone allows patients to maintain daily function without severe daytime drowsiness typical of older relaxants.\n\nEnhanced Mobility: Reduces joint and tissue stiffness, enabling better engagement in physical rehabilitation.\n\nStreamlined Regimen: Combines two therapeutic agents into a single convenient dosage form.\n\nUsage Guidelines\nThis medication must be taken strictly in accordance with a medical prescription.\n\nAdministration: Swallow the tablet whole with water. Do not crush, chew, or split the film-coated tablet.\n\nTiming: Take immediately after a meal to reduce potential gastrointestinal upset, unless directed otherwise by a doctor.\n\nCompliance: Complete the full course prescribed by your physician, and do not alter the recommended dosage.\n\nPotential Side Effects\nWhile generally well-tolerated, some individuals may experience mild side effects, including:\n\nGastrointestinal distress or mild nausea\n\nTransient dizziness or lightheadedness\n\nHeadaches\n\nGeneral fatigue or muscular weakness\n\nRare: Hypersensitivity reactions or cutaneous skin rashes (discontinue use and consult a physician immediately if severe symptoms appear).\n\nSafety Precautions and Considerations\nConsult a medical practitioner prior to initiating treatment if any of the following apply:\n\nPre-existing hepatic (liver) or renal (kidney) impairment\n\nKnown hypersensitivity to Tolperisone, Paracetamol, or related compounds\n\nPregnancy, plans for pregnancy, or active breastfeeding\n\nHistory of chronic alcohol dependency (due to increased liver sensitivity with Paracetamol)\n\nConcurrent use of other medications, particularly other products containing Paracetamol or central nervous system depressants\n\nStorage and Handling\nStore in a cool, dry area below 25°C (77°F).\n\nProtect from direct light, heat, and moisture.\n\nKeep strictly out of reach of children and pets.\n\nCheck the packaging expiration date before administration.\n\nFrequently Asked Questions\nWhat primary conditions does TOPERITIME P 150/325 treat?\n\nIt is indicated for short-term relief from acute musculoskeletal pain, muscle spasms, neck strains, backaches, and related orthopedic disorders.\n\nWhy is Tolperisone combined with Paracetamol?\n\nTolperisone eases muscle tightness at the neurological level, while Paracetamol lowers overall pain perception, creating a synergistic effect that addresses both spasm and pain together.\n\nWill this medication cause severe drowsiness?\n\nTolperisone is specifically designed to exert less sedating activity compared to older muscle relaxants. However, individual sensitivity varies, so caution is advised when driving or operating machinery until individual tolerance is established.\n\nIs TOPERITIME P 150/325 available over the counter?\n\nNo. It requires a valid medical prescription and direct supervision by a registered healthcare professional.", "price": 95.0, "discountamount": 29.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2493, "imageuri": "https://productimages.withfloats.com/actual/6a7722b0ed25653efa18364e.png", "tileimageuri": "https://productimages.withfloats.com/tile/6a7722b0ed25653efa18364e.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-08-08T12:35:59.075Z", "updatedon": "2026-08-08T12:35:59.075Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/tolperisone-hydrochloride-paracetamol-tablets/2493", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "TOPERITIME P 150/325", "category": "ORTHOLOGYRANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69662101a96bbf383231d700", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "FABRICAL MG K₂7", "description": "FABRICAL MG K₂7 represents a scientifically advanced nutritional supplement that combines essential minerals and vitamins in a synergistic formulation designed to support optimal bone health, cardiovascular function, and overall metabolic wellness. This innovative product brings together six critical nutrients—Calcium Citrate Maleate, Magnesium Bisglycinate, Vitamin D3, Vitamin K2-7 (Menaquinone-7), Zinc, and Methylcobalamin—in precise therapeutic ratios that maximize bioavailability and clinical effectiveness.\nUnlike conventional calcium supplements that focus solely on calcium supplementation, FABRICAL MG K₂7 adopts a comprehensive, multi-nutrient approach that addresses the complex interplay between various micronutrients essential for skeletal integrity, neuromuscular function, immune competence, and metabolic regulation. This sophisticated formulation reflects current understanding of nutritional biochemistry, recognizing that optimal health outcomes require balanced supplementation rather than isolated nutrient provision.\nThe product has been meticulously formulated to address the growing epidemic of nutritional deficiencies affecting diverse populations, from elderly individuals experiencing age-related bone loss to young adults with suboptimal dietary intake, pregnant women with increased nutritional demands, and individuals with chronic conditions affecting nutrient absorption or utilization. FABRICAL MG K₂7 serves as a convenient, evidence-based solution for maintaining nutritional adequacy and supporting long-term health across various life stages.\nDetailed Understanding of FABRICAL MG K₂7 Components\nCalcium Citrate Maleate: Superior Calcium Bioavailability\nCalcium Citrate Maleate represents the premium form of calcium supplementation, offering significantly enhanced absorption compared to traditional calcium carbonate. This advanced calcium complex demonstrates approximately 25-30% better bioavailability, making it particularly valuable for individuals with reduced gastric acid production, including elderly populations and those taking proton pump inhibitors or H2-receptor antagonists. Unlike calcium carbonate, which requires acidic conditions for optimal dissolution, Calcium Citrate Maleate can be absorbed efficiently regardless of meal timing or stomach pH, providing greater flexibility and convenience.\nThe maleate component further enhances calcium absorption and utilization by supporting cellular energy metabolism and mitochondrial function. This sophisticated formulation ensures that supplemented calcium reaches target tissues—bones, teeth, muscles, and nerves—where it performs essential physiological functions rather than accumulating in soft tissues where it could potentially contribute to unwanted calcification.\nMagnesium Bisglycinate: The Gentle Magnesium Choice\nMagnesium Bisglycinate, also known as magnesium glycinate, stands as one of the most bioavailable and well-tolerated forms of magnesium supplementation. This chelated form, where magnesium is bound to two molecules of the amino acid glycine, offers exceptional absorption rates approaching 80-90% while minimizing the gastrointestinal side effects—particularly diarrhea—commonly associated with other magnesium forms like magnesium oxide or sulfate.\nMagnesium plays over 300 enzymatic roles throughout the body, making it indispensable for energy production, protein synthesis, muscle and nerve function, blood glucose control, and blood pressure regulation. Within FABRICAL MG K₂7, magnesium works synergistically with calcium, maintaining the critical calcium-magnesium balance essential for proper muscular contraction and relaxation, cardiovascular rhythm stability, and skeletal mineralization.\nVitamin D3: The Sunshine Vitamin in Its Active Form\nVitamin D3 (cholecalciferol) represents the most bioactive form of vitamin D, identical to what human skin synthesizes upon ultraviolet B exposure. This fat-soluble vitamin functions more accurately as a hormone, regulating calcium absorption from the intestines, maintaining serum calcium and phosphorus concentrations within optimal ranges, and modulating bone remodeling by both osteoblasts and osteoclasts.\nBeyond skeletal functions, Vitamin D3 exerts profound influences on immune system regulation, cellular differentiation and proliferation, neuromuscular function, and inflammation modulation. Vitamin D receptors exist throughout the body—in tissues ranging from the brain and heart to immune cells and muscle—highlighting its systemic importance. The inclusion of Vitamin D3 in FABRICAL MG K₂7 ensures that supplemented calcium can be effectively absorbed and utilized, preventing the futility of calcium supplementation in vitamin D-deficient states.\nVitamin K2-7: The Missing Link in Bone and Cardiovascular Health\nVitamin K2-7, specifically the menaquinone-7 (MK-7) form, represents perhaps the most revolutionary component of FABRICAL MG K₂7. This long-chain vitamin K2 demonstrates superior bioavailability and longer half-life compared to vitamin K1 (phylloquinone) found in green vegetables or shorter-chain K2 forms. Vitamin K2-7's critical function involves activating proteins responsible for proper calcium utilization—specifically matrix Gla protein (MGP) and osteocalcin.\nOsteocalcin, produced by bone-building osteoblasts, requires vitamin K2-dependent carboxylation to become active and effectively bind calcium into bone matrix, strengthening skeletal structure. Simultaneously, Vitamin K2-7 activates MGP, which prevents calcium deposition in arterial walls and soft tissues, directing calcium away from cardiovascular structures where it contributes to atherosclerosis and arterial stiffness. This dual action—promoting bone calcification while preventing vascular calcification—makes Vitamin K2-7 uniquely valuable, addressing the “calcium paradox” where individuals may simultaneously experience osteoporosis and arterial calcification.\nZinc: The Multifunctional Essential Mineral\nZinc, incorporated into FABRICAL MG K₂7 in highly bioavailable form, serves numerous critical physiological functions spanning immune competence, wound healing, protein synthesis, DNA synthesis, and cellular division. Regarding bone health specifically, zinc influences bone metabolism by supporting osteoblast activity and collagen synthesis, contributing to bone matrix formation and mineralization. Zinc also functions as a cofactor for alkaline phosphatase, an enzyme essential for bone mineralization.\nBeyond skeletal contributions, zinc supports immune system function, acting as a critical component of innumerable enzymes involved in immune cell development and function. Zinc deficiency impairs both innate and adaptive immunity, increasing susceptibility to infections. The mineral also supports sensory function (taste and smell), cognitive function, reproductive health, and skin integrity.\nMethylcobalamin: The Bioactive Vitamin B12\nMethylcobalamin represents the active, coenzyme form of vitamin B12, requiring no metabolic conversion to exert biological activity. This form demonstrates superior neurological benefits compared to cyanocobalamin, the synthetic form commonly used in supplements. Methylcobalamin directly participates in methionine synthesis and methylation reactions critical for nervous system health, DNA synthesis, red blood cell formation, and homocysteine metabolism.\nElevated homocysteine, resulting from inadequate B12 status, associates with increased cardiovascular disease risk, cognitive decline, and bone fragility. By supporting homocysteine conversion to methionine, methylcobalamin in FABRICAL MG K₂7 contributes to cardiovascular protection and potentially supports bone health through mechanisms independent of its well-established neurological and hematological roles.\nPrimary Uses and Clinical Applications of FABRICAL MG K₂7\nComprehensive Bone Health Support\nThe primary indication for FABRICAL MG K₂7 centers on comprehensive bone health support across various life stages and clinical scenarios. The formulation addresses all critical aspects of skeletal health: providing adequate calcium substrate for mineralization, ensuring calcium absorption through Vitamin D3, directing calcium into bone matrix via Vitamin K2-7, supporting bone matrix formation through magnesium and zinc, and protecting against homocysteine-related bone fragility through methylcobalamin.\nThis makes FABRICAL MG K₂7 particularly valuable for:\nOsteoporosis Prevention and Management: Postmenopausal women and elderly men experiencing age-related bone loss benefit from the formulation's comprehensive approach, potentially slowing bone density decline and reducing fracture risk.\nGrowing Children and Adolescents: During peak bone-building years, FABRICAL MG K₂7 supports optimal skeletal development, helping children and teenagers achieve maximum peak bone mass—a critical determinant of lifelong skeletal health.\nPregnancy and Lactation: Women during pregnancy and breastfeeding experience dramatically increased calcium demands. FABRICAL MG K₂7 helps prevent maternal bone density loss while supporting fetal skeletal development.\nCardiovascular Protection Through Proper Calcium Distribution\nThe Vitamin K2-7 component positions FABRICAL MG K₂7 as more than a bone health supplement—it's a cardiovascular protective formulation. By activating matrix Gla protein, the supplement helps prevent arterial calcification, potentially reducing cardiovascular disease risk. This dual benefit addresses the concerning observation that some individuals taking calcium supplements without adequate Vitamin K2 may experience increased cardiovascular events due to inappropriate calcium deposition in arterial walls.\nNeurological and Cognitive Support\nThe methylcobalamin component provides neurological support, particularly valuable for elderly individuals at risk for vitamin B12 deficiency due to reduced intrinsic factor production or those taking medications that impair B12 absorption (such as metformin or proton pump inhibitors). Adequate B12 status supports cognitive function, mood regulation, nerve conduction, and may help prevent peripheral neuropathy.\nImmune System Enhancement\nBoth zinc and vitamin D3 within FABRICAL MG K₂7 contribute significantly to immune competence. Vitamin D modulates both innate and adaptive immunity, while zinc supports immune cell development and function. This immune support proves particularly relevant during seasonal illness peaks or for individuals with compromised immunity.\nMuscle Function and Exercise Performance\nMagnesium's role in muscle contraction and relaxation, combined with calcium's involvement in excitation-contraction coupling, makes FABRICAL MG K₂7 valuable for athletes and physically active individuals. The formulation may help prevent exercise-associated muscle cramps, support recovery, and maintain electrolyte balance.\nKey Benefits of FABRICAL MG K₂7\nEnhanced Bioavailability and Absorption\nUnlike basic supplements using inferior ingredient forms, FABRICAL MG K₂7 utilizes premium, highly bioavailable compounds:\n\nCalcium Citrate Maleate offers superior absorption compared to calcium carbonate\nMagnesium Bisglycinate provides excellent absorption without gastrointestinal distress\nVitamin D3 is more potent than D2\nVitamin K2-7 (MK-7) has longer half-life and better tissue distribution than K1 or shorter-chain K2 forms\nMethylcobalamin is the active B12 form requiring no conversion\n\nThis superior bioavailability means lower doses can achieve therapeutic effects, reducing pill burden and potential adverse effects while maximizing benefits.\nSynergistic Nutrient Interactions\nFABRICAL MG K₂7's formulation recognizes that nutrients work together, not in isolation:\n\nVitamin D3 enhances calcium absorption while Vitamin K2-7 directs where that calcium goes\nMagnesium supports Vitamin D activation and calcium metabolism\nZinc supports bone matrix formation complementing calcium's role in mineralization\nMethylcobalamin supports methylation pathways that may influence bone health\n\nThis synergy delivers benefits exceeding what individual nutrients could provide separately.\nComprehensive Rather Than Fragmented Nutritional Support\nRather than requiring multiple separate supplements, FABRICAL MG K₂7 provides comprehensive support in a single, convenient formulation. This simplification improves compliance, reduces costs compared to purchasing individual supplements, and eliminates concerns about nutrient imbalances from uncoordinated supplementation.\nProtection Against the Calcium Paradox\nPerhaps the most significant benefit stems from the Vitamin K2-7 inclusion, which addresses the calcium paradox—simultaneously strengthening bones while protecting cardiovascular health by preventing arterial calcification. This represents a critical advancement over traditional calcium supplements that may inadvertently increase cardiovascular risk when taken without adequate Vitamin K2.\nSupport Across Multiple Physiological Systems\nBeyond bones, FABRICAL MG K₂7 benefits:\n\nCardiovascular System: Through arterial protection and homocysteine management\nNervous System: Via methylcobalamin's neurological support\nImmune System: Through vitamin D3 and zinc's immunomodulatory effects\nMuscular System: Via magnesium and calcium's roles in contraction\nMetabolic System: Through magnesium's involvement in glucose metabolism\n\nThis multi-system support delivers value far exceeding simple bone health supplementation.\nPotential Side Effects and Safety Considerations\nGenerally Well-Tolerated with Minimal Side Effects\nFABRICAL MG K₂7, when taken as directed, demonstrates excellent tolerability in most individuals. The selection of highly bioavailable, gentle nutrient forms specifically minimizes adverse effects common with inferior formulations.\nMild Gastrointestinal Effects\nSome users may initially experience mild digestive symptoms including:\n\nSlight nausea, particularly if taken on an empty stomach\nMinor bloating or gas\nMild constipation (though less likely than with calcium carbonate formulations)\n\nThese effects typically resolve within a few days as the body adjusts and can be minimized by taking the supplement with meals and ensuring adequate hydration.\nRare Allergic Reactions\nAlthough uncommon, some individuals may experience hypersensitivity to ingredients or excipients in the formulation. Signs include rash, itching, or swelling. Discontinuation and medical consultation are warranted if such reactions occur.\nConsiderations for Specific Populations\nIndividuals on Anticoagulants: Vitamin K2, while generally safer regarding coagulation than K1, may theoretically interact with warfarin. Patients on anticoagulation therapy should consult healthcare providers before starting FABRICAL MG K₂7, though recent evidence suggests K2 supplementation at consistent doses may not significantly affect INR stability.\nKidney Disease Patients: Individuals with chronic kidney disease should consult nephrologists before supplementing with calcium, magnesium, or vitamin D due to altered mineral metabolism and increased calcification risks in renal impairment.\nHypercalcemia Risk: Those with conditions predisposing to elevated calcium (hyperparathyroidism, sarcoidosis, certain cancers) should avoid supplementation without medical supervision.\nImportance of Appropriate Dosing\nExceeding recommended doses may increase adverse effect risks including:\n\nHypercalcemia (excessive calcium) causing nausea, constipation, kidney stones\nHypermagnesemia (excessive magnesium) causing diarrhea, cardiac abnormalities\nVitamin D toxicity (though requiring very high doses sustained over time)\n\nFollowing manufacturer's recommendations and consulting healthcare providers regarding individual needs ensures safe, effective use.\nRecommended Usage and Dosage Guidelines\nFABRICAL MG K₂7 should be taken according to manufacturer recommendations, typically one to two tablets daily with meals for optimal absorption of fat-soluble vitamins (D3 and K2-7). Taking the supplement with food containing some dietary fat further enhances absorption of these critical nutrients while minimizing potential gastrointestinal discomfort.\nConsistency in timing supports optimal benefits, as regular daily supplementation maintains stable nutrient levels. For individuals on multiple medications, spacing FABRICAL MG K₂7 administration at least two hours from certain medications (particularly thyroid hormones, bisphosphonates, or antibiotics) prevents potential absorption interference.\nIndividual requirements vary based on age, sex, dietary intake, health status, and specific deficiency risks. Healthcare provider consultation helps determine whether standard dosing suffices or whether adjustments are warranted. Periodic monitoring of vitamin D levels and other relevant biomarkers may be recommended to ensure supplementation achieves therapeutic goals without overshooting into excess.\nConclusion: FABRICAL MG K₂7 as a Comprehensive Nutritional Solution\nFABRICAL MG K₂7 stands as a sophisticated, scientifically formulated nutritional supplement that transcends traditional approaches to bone health support. By combining six synergistic nutrients in highly bioavailable forms, this innovative product addresses the complex, interconnected nature of skeletal health, cardiovascular protection, neurological function, and overall metabolic wellness.\nThe formulation's greatest strength lies in its comprehensive approach—recognizing that optimal health outcomes require balanced nutrition rather than isolated nutrient provision. The inclusion of Vitamin K2-7 particularly distinguishes FABRICAL MG K₂7 from conventional calcium supplements, addressing the critical calcium paradox and ensuring supplemented calcium strengthens bones while protecting cardiovascular structures.\nFor individuals seeking to support bone density, prevent osteoporosis, ensure adequate nutritional status during life stages of increased demand, or simply maintain optimal health through evidence-based supplementation, FABRICAL MG K₂7 offers a convenient, effective solution backed by nutritional science. Its excellent tolerability, superior ingredient quality, and multi-system benefits make it suitable for diverse populations from growing adolescents to active adults and elderly individuals concerned about age-related health challenges.\nAs with any nutritional supplement, FABRICAL MG K₂7 works best as part of a comprehensive health strategy including balanced nutrition, regular physical activity, adequate sleep, stress management, and appropriate medical care. It complements rather than replaces healthy lifestyle practices, providing nutritional insurance that helps fill gaps in modern diets while supporting long-term wellness.\nWhether you're proactively supporting your skeletal health, addressing identified nutritional deficiencies, or seeking comprehensive multi-nutrient support, FABRICAL MG K₂7 represents a premium choice that combines scientific sophistication with practical convenience, delivering measurable benefits that support vibrant health across all life stages.\n\nDisclaimer: This information is for educational purposes and does not constitute medical advice. Individual nutritional needs vary significantly based on numerous factors. Consult qualified healthcare professionals before starting any supplement regimen, particularly if you have existing health conditions, take medications, are pregnant or nursing, or have specific health concerns. Keep supplements out of reach of children and store according to manufacturer recommendations to maintain product integrity and safety.", "price": 250.0, "discountamount": 75.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2274, "imageuri": "https://productimages.withfloats.com/actual/696621081f531945cbd90a0c.png", "tileimageuri": "https://productimages.withfloats.com/tile/696621081f531945cbd90a0c.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-13T10:40:01.051Z", "updatedon": "2026-06-09T10:20:10.642Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//fabrical-mg-k-7/2274", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "FABRICAL MG K₂7", "category": "ORTHOLOGYRANG", "tags": [ "calcium citrate maleate magnesium bisglycinate tablets", "calcium citrate maleate with vitamin d3 k2 mk7", "magnesium bisglycinate with methylcobalamin tablets", "calcium citrate maleate vitamin k2-7 tablets", "best calcium citrate maleate tablets for bones", "magnesium bisglycinate tablets for muscle cramps", "methylcobalamin zinc tablets for nerve health", "calcium citrate maleate tablets for osteoporosis", "best calcium supplement with k2-7 for bone strength", "vitamin k2-7 mk7 with calcium benefits", "bone strength tablets with calcium magnesium zinc", "vitamin d3 k2 calcium tablets for elderly", "calcium citrate maleate tablets price in india", "best calcium magnesium vitamin d3 k2 tablets", "best bone health tablets with vitamin k2-7", "calcium magnesium zinc methylcobalamin tablets" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69623e6c95697555dd1afd67", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Esomeprazole and Itopride", "description": "ESMOSTRUM IT: Comprehensive Product Guide\nProduct Overview\nESMOSTRUM IT is an advanced pharmaceutical formulation that combines two potent active ingredients—Esomeprazole and Itopride—to provide comprehensive relief from gastrointestinal disorders. This dual-action medication represents a significant advancement in the management of acid-related digestive conditions and motility disorders. By combining a proton pump inhibitor with a prokinetic agent, ESMOSTRUM IT addresses both the underlying causes and symptomatic manifestations of various digestive ailments, offering patients a complete therapeutic solution in a single, convenient dosage form.\nThe synergistic combination of Esomeprazole and Itopride makes ESMOSTRUM IT particularly effective for individuals suffering from gastroesophageal reflux disease (GERD), functional dyspepsia, and other conditions where both excessive acid production and impaired gastric motility contribute to discomfort and disease progression.\nActive Pharmaceutical Ingredients\nEsomeprazole\nEsomeprazole is the S-isomer of omeprazole and belongs to the class of medications known as proton pump inhibitors (PPIs). It works by specifically and irreversibly blocking the hydrogen-potassium adenosine triphosphatase enzyme system (the proton pump) located in the gastric parietal cells. This mechanism effectively reduces gastric acid secretion, providing sustained relief from acid-related symptoms and allowing damaged esophageal and gastric tissue to heal.\nItopride\nItopride is a prokinetic agent that enhances gastrointestinal motility through a dual mechanism of action. It acts as both a dopamine D2 receptor antagonist and an acetylcholinesterase inhibitor. By blocking dopamine receptors, it removes the inhibitory effect of dopamine on gastrointestinal motility, while its acetylcholinesterase inhibition increases acetylcholine levels, further promoting coordinated gastric contractions and improved gastric emptying.\nTherapeutic Uses and Indications\nESMOSTRUM IT is prescribed for a wide range of gastrointestinal conditions where both acid suppression and enhanced motility are therapeutically beneficial:\nGastroesophageal Reflux Disease (GERD)\nESMOSTRUM IT provides exceptional relief for patients suffering from GERD, a chronic condition where stomach acid frequently flows back into the esophagus. The esomeprazole component reduces acid production, while itopride improves the tone of the lower esophageal sphincter and accelerates gastric emptying, thereby reducing the frequency and severity of reflux episodes.\nFunctional Dyspepsia\nFor patients experiencing persistent or recurrent upper abdominal discomfort without an identifiable organic cause, ESMOSTRUM IT addresses multiple pathophysiological mechanisms. It relieves symptoms such as early satiety, postprandial fullness, epigastric pain, and bloating by normalizing gastric acid levels and improving gastric accommodation and emptying.\nPeptic Ulcer Disease\nESMOSTRUM IT aids in the healing of gastric and duodenal ulcers by creating an optimal healing environment through sustained acid suppression. The prokinetic action of itopride helps prevent stasis of gastric contents, which can exacerbate ulcer symptoms.\nNon-Ulcer Dyspepsia\nMany patients experience dyspeptic symptoms without evidence of ulceration. ESMOSTRUM IT effectively manages these symptoms by addressing both acid hypersecretion and delayed gastric emptying, two key factors in non-ulcer dyspepsia.\nGastroparesis-Related Symptoms\nIn conditions where gastric emptying is significantly delayed, the itopride component of ESMOSTRUM IT helps restore more normal gastric motility patterns, reducing associated symptoms like nausea, vomiting, and abdominal distension.\nKey Benefits and Advantages\nDual Mechanism of Action\nThe primary advantage of ESMOSTRUM IT lies in its comprehensive approach to gastrointestinal health. Rather than addressing only acid production or motility in isolation, this combination therapy tackles both aspects simultaneously, providing more complete symptom relief and better therapeutic outcomes.\nSuperior Acid Suppression\nEsomeprazole offers more consistent and prolonged acid suppression compared to many other acid-reducing medications. It provides sustained relief throughout the day and night, allowing patients to experience fewer breakthrough symptoms and better quality of life.\nEnhanced Gastric Motility\nThe itopride component specifically targets motility issues without crossing the blood-brain barrier significantly, meaning it provides prokinetic benefits with minimal central nervous system side effects. This results in improved gastric emptying, reduced bloating, and decreased feelings of fullness after meals.\nRapid Symptom Relief\nMany patients experience noticeable improvement in their symptoms within the first few days of treatment with ESMOSTRUM IT. The combination therapy addresses multiple symptom pathways simultaneously, leading to faster and more comprehensive relief.\nImproved Quality of Life\nBy effectively managing symptoms such as heartburn, regurgitation, nausea, bloating, and early satiety, ESMOSTRUM IT significantly enhances patients' daily functioning and overall well-being. Patients report better sleep quality, improved dietary tolerance, and reduced anxiety related to their digestive symptoms.\nConvenient Dosing\nThe combination of two active ingredients in a single formulation improves medication adherence by reducing pill burden. Patients appreciate the simplicity of taking one medication instead of multiple separate preparations.\nMucosal Healing Properties\nBeyond symptom relief, ESMOSTRUM IT promotes actual healing of damaged esophageal and gastric mucosa. The reduced acid environment created by esomeprazole allows inflamed and eroded tissue to regenerate properly.\nReduced Risk of Complications\nBy effectively controlling acid reflux and improving gastric emptying, ESMOSTRUM IT helps prevent potential complications of chronic GERD, such as esophageal strictures, Barrett's esophagus, and respiratory complications from aspiration.\nDosage and Administration\nESMOSTRUM IT should be taken exactly as prescribed by a healthcare professional. Typically, the medication is administered orally, preferably before meals to optimize its therapeutic effects. The standard dosing regimen usually involves once or twice daily administration, though individual requirements may vary based on the severity of the condition and patient response.\nThe medication should be swallowed whole with water and should not be crushed, chewed, or split, as this may affect the drug's release mechanism and therapeutic efficacy. Patients should maintain regular dosing schedules to ensure optimal acid suppression and motility enhancement throughout the day.\nSide Effects and Safety Considerations\nLike all medications, ESMOSTRUM IT may cause side effects in some individuals, though not everyone experiences them. Understanding potential adverse effects helps patients identify and report concerning symptoms promptly.\nCommon Side Effects\nGastrointestinal Effects: Some patients may experience diarrhea, constipation, abdominal pain, nausea, or flatulence, particularly during initial treatment. These effects are usually mild and often resolve as the body adjusts to the medication.\nHeadache: Mild to moderate headaches occur in a small percentage of patients and typically diminish with continued use.\nDizziness: Some individuals may experience lightheadedness or dizziness, particularly when standing up quickly.\nDry Mouth: Reduced saliva production may occur, leading to oral dryness and discomfort.\nLess Common Side Effects\nSkin Reactions: Rash, itching, or other dermatological manifestations may develop in sensitive individuals.\nSleep Disturbances: Some patients report insomnia or unusual dreams while taking the medication.\nIncreased Prolactin Levels: Itopride may cause mild elevation in prolactin levels, though clinical manifestations are rare.\nTaste Alterations: Changes in taste perception or metallic taste may occur temporarily.\nSerious Side Effects (Rare)\nWhile uncommon, certain serious adverse effects require immediate medical attention:\n\nSevere allergic reactions including difficulty breathing, facial swelling, or severe skin reactions\nSevere diarrhea that persists or contains blood\nIrregular heartbeat or palpitations\nMuscle weakness or pain\nSeizures or tremors\nSigns of liver problems including jaundice, dark urine, or persistent nausea\n\nLong-Term Considerations\nExtended use of proton pump inhibitors like esomeprazole has been associated with certain risks that patients should discuss with their healthcare providers:\n\nPotential reduction in calcium, magnesium, and vitamin B12 absorption\nSlightly increased risk of bone fractures with prolonged use\nPossible increased susceptibility to certain gastrointestinal infections\nRare cases of kidney problems\n\nRegular monitoring and periodic assessment by healthcare professionals help minimize these risks while maintaining therapeutic benefits.\nPrecautions and Contraindications\nPatients should inform their healthcare provider about all existing medical conditions, particularly liver disease, kidney problems, osteoporosis, low magnesium levels, or any gastrointestinal bleeding. ESMOSTRUM IT may interact with certain medications, including blood thinners, antifungals, HIV medications, and certain antibiotics. A complete medication review ensures safe and effective therapy.\nPregnant or breastfeeding women should only use ESMOSTRUM IT under strict medical supervision, as the safety profile in these populations requires careful consideration of potential risks and benefits.\nLifestyle Recommendations\nFor optimal therapeutic outcomes, patients taking ESMOSTRUM IT should complement their medication regimen with appropriate lifestyle modifications:\n\nAvoid trigger foods that exacerbate acid reflux, such as spicy foods, citrus, chocolate, caffeine, and alcohol\nMaintain a healthy body weight to reduce abdominal pressure\nEat smaller, more frequent meals rather than large portions\nAvoid lying down immediately after eating; wait at least two to three hours\nElevate the head of the bed if nighttime symptoms occur\nQuit smoking, as tobacco use significantly worsens reflux symptoms\nManage stress through relaxation techniques, as stress can exacerbate digestive symptoms\n\nConclusion\nESMOSTRUM IT represents a sophisticated and effective pharmaceutical solution for individuals struggling with complex gastrointestinal disorders involving both acid hypersecretion and impaired motility. By combining the powerful acid-suppressing capabilities of esomeprazole with the prokinetic benefits of itopride, this medication offers comprehensive symptom management that addresses the multifaceted nature of digestive disorders.", "price": 182.0, "discountamount": 54.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2273, "imageuri": "https://productimages.withfloats.com/actual/69623e6fd8491171373812e3.png", "tileimageuri": "https://productimages.withfloats.com/tile/69623e6fd8491171373812e3.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-10T11:56:28.061Z", "updatedon": "2026-04-21T09:38:56.999Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//esomeprazole-and-itopride/2273", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "ESMOSTRUM IT", "category": "GASTROLOGYRANGE", "tags": [ "esomeprazole and itopride", "esomeprazole and itopride capsules uses in hindi", "esomeprazole and itopride capsules uses", "esomeprazole and itopride brand name", "esomeprazole and itopride hydrochloride", "esomeprazole and itopride capsules", "esomeprazole and itopride uses", "esomeprazole and itopride hydrochloride capsules", "esomeprazole and itopride hydrochloride uses", "esomeprazole and itopride hydrochloride price", "esomeprazole and itopride hydrochloride price in india", "buy online Esomeprazole and Itopride" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6960c83f3056ad8a5a1aecba", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Cinnarizine and Domperidone Tablets ", "description": "CLANARIZINE DOM represents an advanced pharmaceutical combination that brings together two potent therapeutic agents—Cinnarizine and Domperidone—in a single convenient tablet formulation. This innovative combination medication addresses multiple aspects of vestibular disorders, motion sickness, and associated nausea and vomiting, providing comprehensive relief for patients suffering from these debilitating conditions. Manufactured under stringent quality control standards, CLANARIZINE DOM offers a synergistic approach to managing symptoms that significantly impact quality of life and daily functioning.The combination of Cinnarizine and Domperidone in CLANARIZINE DOM is based on sound pharmacological principles. While Cinnarizine works primarily on the vestibular system to reduce dizziness and vertigo, Domperidone acts as an effective antiemetic to control nausea and vomiting. Together, these two active ingredients provide more comprehensive symptom control than either agent alone, making CLANARIZINE DOM an excellent choice for patients experiencing vestibular disturbances accompanied by gastrointestinal symptoms.This combination therapy is particularly valuable because vertigo, dizziness, and motion sickness are frequently accompanied by nausea and vomiting. Patients suffering from these conditions often find that addressing only one aspect of their symptoms provides insufficient relief. CLANARIZINE DOM's dual-action formula tackles both the underlying vestibular dysfunction and the accompanying gastrointestinal distress, offering patients a more complete therapeutic solution that improves both comfort and functional capacity.Understanding the Active IngredientsCinnarizine is a calcium channel blocker with specific antihistaminic and vestibular suppressant properties. Unlike systemic calcium channel blockers used for cardiovascular conditions, Cinnarizine selectively acts on the blood vessels in the inner ear and brain, improving blood flow to these areas. This enhanced circulation helps reduce the frequency and severity of vertigo attacks while also preventing motion sickness. Cinnarizine also possesses mild antihistaminic effects that contribute to its anti-nausea properties, though this is not its primary mechanism of action.The medication works by blocking calcium channels in the vestibular system, which helps stabilize the sensory organs responsible for balance. By reducing the excessive stimulation of the vestibular apparatus, Cinnarizine decreases the sensation of spinning or imbalance that characterizes vertigo. Additionally, its vasodilatory effects improve microcirculation in the inner ear, which can be beneficial for conditions where reduced blood flow contributes to symptoms.Domperidone is a peripheral dopamine antagonist that acts primarily as a prokinetic and antiemetic agent. Unlike some antiemetic medications that cross the blood-brain barrier and cause sedation or extrapyramidal side effects, Domperidone works predominantly in the peripheral nervous system. It blocks dopamine receptors in the chemoreceptor trigger zone (CTZ) located outside the blood-brain barrier, effectively preventing nausea and vomiting without causing significant central nervous system effects.Domperidone also enhances gastrointestinal motility by promoting coordinated contractions of the stomach and upper small intestine. This prokinetic effect helps empty the stomach more efficiently, reducing feelings of fullness, bloating, and discomfort that often accompany vestibular disorders. By accelerating gastric emptying, Domperidone also reduces the likelihood of gastroesophageal reflux, which can exacerbate nausea in some patients.The combination of these two medications in CLANARIZINE DOM creates a complementary therapeutic effect. While Cinnarizine addresses the vestibular component of dizziness and vertigo, Domperidone manages the gastrointestinal symptoms that frequently accompany these conditions. This dual approach provides more comprehensive symptom relief and improves overall treatment outcomes compared to monotherapy with either agent alone.Clinical Applications and UsesCLANARIZINE DOM is indicated for a wide range of conditions characterized by vertigo, dizziness, and associated nausea. Understanding these clinical applications helps healthcare providers select appropriate candidates for this combination therapy.Vestibular Disorders: The primary indication for CLANARIZINE DOM includes various vestibular disorders that cause vertigo and imbalance. These conditions include Ménière's disease, benign paroxysmal positional vertigo (BPPV), vestibular neuritis, and labyrinthitis. Patients with these disorders experience episodes of spinning sensation, loss of balance, and often severe nausea. CLANARIZINE DOM helps reduce the frequency and intensity of vertigo attacks while controlling the accompanying gastrointestinal symptoms.Motion Sickness: CLANARIZINE DOM is highly effective for preventing and treating motion sickness, whether related to travel by car, boat, airplane, or amusement park rides. The medication can be taken prophylactically before travel or at the onset of symptoms. The combination is particularly useful for individuals who experience severe nausea and vomiting with motion sickness, as Domperidone provides powerful antiemetic effects that complement Cinnarizine's anti-motion-sickness properties.Migraine-Associated Vertigo: Many patients with migraines experience vestibular symptoms, including dizziness, vertigo, and motion sensitivity, either during migraine attacks or as independent episodes. CLANARIZINE DOM can help manage these vestibular manifestations of migraine, reducing both the vertigo and the nausea that often accompany migraine headaches.Post-Concussion Syndrome: Following head injuries, some patients develop persistent dizziness, balance problems, and nausea as part of post-concussion syndrome. CLANARIZINE DOM may provide symptomatic relief for these patients during their recovery period, though it should be used as part of a comprehensive treatment approach that includes rest, gradual return to activities, and vestibular rehabilitation when appropriate.Cerebrovascular Insufficiency: In older adults with reduced blood flow to the brain, symptoms such as dizziness, vertigo, tinnitus (ringing in the ears), and cognitive difficulties may develop. Cinnarizine's vasodilatory properties can improve cerebral circulation, potentially reducing these symptoms. The addition of Domperidone helps manage any associated nausea.Radiation-Induced or Chemotherapy-Induced Nausea: While not a primary indication, some healthcare providers use CLANARIZINE DOM as adjunctive therapy for patients undergoing cancer treatment who experience both nausea and dizziness. Domperidone's strong antiemetic properties are particularly valuable in this context.Key Benefits of CLANARIZINE DOMThe unique combination of Cinnarizine and Domperidone in CLANARIZINE DOM offers numerous advantages that make it a preferred choice for managing vestibular disorders and associated symptoms.Comprehensive Symptom Control: The primary benefit of CLANARIZINE DOM is its ability to address multiple symptoms simultaneously. Rather than requiring patients to take separate medications for vertigo and nausea, this combination provides unified treatment in a single tablet. This comprehensive approach improves symptom control across the full spectrum of vestibular disorder manifestations, from the spinning sensation to the gastrointestinal distress that often accompanies it.Improved Patient Compliance: Taking multiple medications can be burdensome, particularly for patients who feel dizzy or nauseated. CLANARIZINE DOM simplifies the treatment regimen by combining two medications in one tablet, making it easier for patients to adhere to their prescribed therapy. Better compliance translates to better outcomes, as consistent medication use is essential for managing chronic vestibular conditions.Synergistic Therapeutic Effects: The combination of Cinnarizine and Domperidone creates synergistic effects that enhance overall efficacy. While Cinnarizine reduces vestibular stimulation and improves inner ear blood flow, Domperidone prevents nausea and promotes gastric emptying. This dual action addresses both the cause and consequences of vestibular dysfunction, providing more complete relief than either medication alone.Reduced Central Nervous System Side Effects: Because Domperidone works primarily in the peripheral nervous system rather than crossing the blood-brain barrier extensively, CLANARIZINE DOM causes less sedation and fewer cognitive effects compared to some alternative antiemetic medications. This allows patients to maintain better alertness and function during treatment, which is particularly important for those who need to continue working or performing daily activities.Enhanced Quality of Life: Vertigo and chronic dizziness significantly impair quality of life, limiting mobility, social interactions, and occupational functioning. The nausea and vomiting that accompany these conditions add another layer of disability. By effectively controlling both vestibular and gastrointestinal symptoms, CLANARIZINE DOM helps restore patients' ability to engage in normal activities, improving overall life satisfaction and functional independence.Fast Onset of Action: CLANARIZINE DOM provides relatively rapid symptom relief, with many patients experiencing improvement within 30 minutes to 2 hours after taking the medication. This quick onset is particularly valuable for acute episodes of vertigo or when taking the medication prophylactically before situations that might trigger motion sickness.Suitable for Long-Term Use: For patients with chronic vestibular disorders requiring ongoing treatment, CLANARIZINE DOM is generally safe for extended use when properly monitored by a healthcare provider. The medication maintains its effectiveness over time without significant tolerance development, making it suitable for long-term symptom management.Improved Gastric Emptying: The prokinetic effects of Domperidone benefit not only nausea but also other gastrointestinal symptoms such as early satiety, bloating, and upper abdominal discomfort. Patients with vestibular disorders often develop gastroparesis or delayed gastric emptying secondary to their condition, and Domperidone addresses this issue effectively.Vascular Benefits: Cinnarizine's ability to improve blood flow to the inner ear and brain provides additional benefits beyond symptom control. Enhanced microcirculation may support healing and recovery in conditions where vascular insufficiency contributes to vestibular dysfunction.Side Effects and Safety ConsiderationsLike all medications, CLANARIZINE DOM can cause side effects, though not everyone experiences them. Understanding potential adverse effects helps patients recognize when to seek medical attention and allows healthcare providers to monitor therapy appropriately.Common Side Effects:The most frequently reported side effect of CLANARIZINE DOM is drowsiness or sedation, occurring in approximately 10-20% of patients. This effect is primarily attributable to Cinnarizine's antihistaminic properties. Patients should avoid driving or operating machinery until they know how the medication affects them. Taking the medication at bedtime can minimize daytime drowsiness for some patients.Dry mouth is another common side effect, affecting roughly 10-15% of patients. This occurs due to anticholinergic effects and can be managed by sipping water frequently, chewing sugar-free gum, or using saliva substitutes if severe. Maintaining good oral hygiene is important to prevent dental problems associated with reduced saliva production.Mild gastrointestinal symptoms, including constipation, abdominal discomfort, or changes in bowel habits, may occur. While Domperidone promotes gastric emptying, it can occasionally alter bowel motility. These effects are usually mild and resolve with continued use or dose adjustment.", "price": 55.0, "discountamount": 17.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2271, "imageuri": "https://productimages.withfloats.com/actual/6960c8410b0da405bc908e58.png", "tileimageuri": "https://productimages.withfloats.com/tile/6960c8410b0da405bc908e58.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-09T09:19:59.281Z", "updatedon": "2026-03-12T09:24:10.244Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//cinnarizine-and-domperidone-tablets-/2271", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CLANARIZINE DOM", "category": "NEUROLOGY RANGE", "tags": [ "cinnarizine and domperidone tablet uses", "what is cinnarizine & domperidone tablet used for", "cinnarizine domperidone combination medicine benefits", "how cinnarizine domperidone tablet works", "cinnarizine domperidone tablet for vertigo treatment", "cinnarizine domperidone tablet for inner ear problem", "cinnarizine domperidone tablet for balance disorder", "cinnarizine domperidone tablet for travel sickness", "cinnarizine domperidone tablet for gastric nausea", "cinnarizine & domperidone tablet price in india", "cinnarizine domperidone tablet brand name", "cinnarizine domperidone tablet manufacturer in india" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6662aa04db100e1fdc2dcb68", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "VILDIABATE 100 ", "description": "VILDIABATE 100 \nVildagliptin (100mg)\nVILDIABATE 100 is a medication designed to manage type 2 diabetes mellitus by targeting specific aspects of glucose regulation. It contains Vildagliptin, an oral antidiabetic agent that belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors. Vildagliptin works by inhibiting the enzyme DPP-4, which is responsible for degrading incretin hormones like GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic peptide).\n\nHere are key points about VILDIABATE 100:\n\nMechanism of Action: Vildagliptin acts by inhibiting DPP-4, thereby increasing the levels of GLP-1 and GIP. These hormones play crucial roles in glucose metabolism:\n\nGLP-1 stimulates insulin secretion from pancreatic beta cells in a glucose-dependent manner. It also inhibits glucagon secretion, reduces appetite, and slows gastric emptying.\nGIP enhances insulin release in response to meals, contributing to postprandial glucose control.\nBlood Sugar Control: By enhancing insulin secretion and reducing glucagon levels, VILDIABATE 100 helps lower blood sugar levels, especially after meals. This mechanism targets both fasting and postprandial hyperglycemia, contributing to overall glycemic control.\n\nDosage and Administration: VILDIABATE 100 is typically taken orally once daily, preferably with a meal to maximize its effects on postprandial glucose levels. The dosage may vary depending on individual needs and response to treatment. It's essential to follow your healthcare provider's instructions regarding dosage and timing.\n\nEfficacy and Safety: Clinical studies have demonstrated the efficacy of Vildagliptin in lowering HbA1c levels (a marker of long-term glucose control) and improving glycemic parameters. It is generally well-tolerated, with common side effects including headache, nasopharyngitis (inflammation of the nose and throat), and upper respiratory tract infections. Serious side effects are rare but may include pancreatitis or hypersensitivity reactions.\n\nCombination Therapy: VILDIABATE 100 may be prescribed as monotherapy or in combination with other antidiabetic medications such as metformin or sulfonylureas. Combining medications with different mechanisms of action can provide synergistic benefits in managing diabetes.\n\nMonitoring and Follow-Up: Regular monitoring of blood sugar levels, kidney function, and other relevant parameters is important during treatment with VILDIABATE 100. Your healthcare provider may adjust the dosage or add/modify other medications based on your response and individual needs.\n\nLifestyle Modifications: In addition to medication, lifestyle modifications such as a healthy diet, regular exercise, weight management, and avoiding tobacco and excessive alcohol intake are essential components of diabetes management.\n\nIn conclusion, VILDIABATE 100 containing Vildagliptin is an effective oral antidiabetic medication that helps regulate blood sugar levels in patients with type 2 diabetes. It acts by enhancing insulin secretion and reducing postprandial glucose levels, contributing to improved glycemic control. However, it should be used under medical supervision, and adherence to prescribed dosage and lifestyle recommendations is crucial for optimal diabetes management.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order Now\nhttps://www.sterisonline.com/product/vildiabate-100-133452\n\n\n\n\n\n", "price": 275.0, "discountamount": 82.5, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "GIP", "nose", "GLP-1", "EMAIL", "class", "meals", "Order", "timing", "throat", "enzyme", "Safety", "Dosage", "marker", "tobacco", "fasting", "response", "addition", "appetite", "headache", "patients", "Efficacy", "metformin", "Follow-Up", "adherence", "treatment", "VILDIABATE", "conclusion", "key points", "information", "monotherapy", "healthy diet", "instructions", "sterisonline", "pancreatitis", "inflammation", "sterispharma", "HbA1c levels", "CALL/WHATSAPP", "sulfonylureas", "crucial roles", "Administration", "insulin release", "nasopharyngitis", "kidney function", "glucagon levels", "gastric emptying", "specific aspects", "Clinical studies", "individual needs", "regular exercise", "other medications", "Vildagliptin acts", "incretin hormones", "DPP-4) inhibitors", "weight management", "insulin secretion", "glucose metabolism", "glucose regulation", "glucagon secretion", "blood sugar levels", "Regular monitoring", "Combination Therapy", "glycemic parameters", "common side effects", "Blood Sugar Control", "medical supervision", "healthcare provider", "essential components", "synergistic benefits", "different mechanisms", "Serious side effects", "pancreatic beta cells", "dipeptidyl peptidase-4", "oral antidiabetic agent", "Lifestyle Modifications", "glucose-dependent manner", "excessive alcohol intake", "overall glycemic control", "type 2 diabetes mellitus", "lifestyle recommendations", "other relevant parameters", "long-term glucose control", "hypersensitivity reactions", "postprandial hyperglycemia", "optimal diabetes management", "postprandial glucose levels", "postprandial glucose control", "other antidiabetic medications", "upper respiratory tract infections", "effective oral antidiabetic medication", "glucose-dependent insulinotropic peptide" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1491, "imageuri": "https://productimages.withfloats.com/actual/6662aa0b364f23242470b3ca.png", "tileimageuri": "https://productimages.withfloats.com/tile/6662aa0b364f23242470b3ca.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-07T06:34:44.056Z", "updatedon": "2026-03-13T06:44:28.496Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//vildiabate-100-/1491", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "VILDIABATE 100 ", "category": "DIABETIC RANGE", "tags": [ "VILDIABATE 100", "Vildagliptin (100mg)", "Vildagliptin 100 mg uses", "Vildagliptin 100 mg price", "Vildagliptin 100 mg SR brand Name", "Vildagliptin 100 mg brands in India", "", "Vildagliptin 100 mg generic medicine", "Vildagliptin 100 mg side effects" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "665f081d8da3a81d5c69e8ec", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "GLIDAPAFLOZIN 10 ", "description": "GLIDAPAFLOZIN 10 \nDapagliflozin (10mg)\nIntroduction\nGLIDAPAFLOZIN 10 is a highly effective medication formulated specifically for the treatment of Type 2 diabetes. This oral tablet contains 10 mg of Dapagliflozin, an SGLT2 inhibitor that plays a crucial role in managing blood glucose levels and supporting overall cardiovascular health.\n\nMechanism of Action\n\nDapagliflozin (10 mg): Dapagliflozin operates by inhibiting the sodium-glucose cotransporter 2 (SGLT2) in the kidneys. This inhibition prevents the reabsorption of glucose back into the bloodstream, promoting the excretion of glucose through urine. This process not only helps lower blood sugar levels but also aids in calorie reduction and weight management.\nBenefits\nGLIDAPAFLOZIN 10 is particularly beneficial for patients looking to control their blood sugar levels effectively while also addressing other metabolic aspects like weight and blood pressure. It has been associated with cardiovascular benefits, making it a preferred choice for diabetic patients with heart-related concerns.\n\nDosage and Administration\n\nDosage: The recommended starting dose is one 10 mg tablet per day. Dosage adjustments should be based on individual efficacy and tolerability, under the guidance of a healthcare professional.\nAdministration: GLIDAPAFLOZIN 10 should be taken in the morning, with or without food. Consistency in taking the medication at the same time each day is important for maintaining stable glucose levels.\nSide Effects\nThe most common side effects of GLIDAPAFLOZIN 10 include genital and urinary tract infections due to the increased glucose in the urine. Patients may also experience signs of dehydration and low blood pressure. It is important for users to stay well-hydrated and monitor for signs of excessive urination and thirst.\n\nConclusion\nGLIDAPAFLOZIN 10 offers an effective, focused approach to managing Type 2 diabetes through its unique action on renal glucose processing. It simplifies diabetes management by providing a once-daily oral treatment that supports blood sugar control while potentially improving cardiovascular and metabolic health. As with any medication, it is crucial to consult a healthcare provider to tailor the treatment to individual needs and circumstances.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order Now\nhttps://www.sterisonline.com/product/glidapaflozin-10-133427\n\n\n\n\n\n", "price": 240.0, "discountamount": 72.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "day", "food", "Order", "signs", "users", "EMAIL", "urine", "thirst", "choice", "kidneys", "genital", "morning", "guidance", "same time", "Mechanism", "excretion", "Conclusion", "inhibition", "Consistency", "oral tablet", "dehydration", "information", "bloodstream", "Introduction", "reabsorption", "crucial role", "sterispharma", "tolerability", "sterisonline", "GLIDAPAFLOZIN", "circumstances", "CALL/WHATSAPP", "Dapagliflozin", "unique action", "starting dose", "oral treatment", "Type 2 diabetes", "SGLT2 inhibitor", "one 10 mg tablet", "metabolic health", "individual needs", "weight management", "diabetic patients", "calorie reduction", "blood sugar levels", "Dosage adjustments", "low blood pressure", "individual efficacy", "common side effects", "excessive urination", "diabetes management", "healthcare provider", "blood sugar control", "effective medication", "blood glucose levels", "stable glucose levels", "Administration Dosage", "heart-related concerns", "cardiovascular benefits", "healthcare professional", "other metabolic aspects", "urinary tract infections", "renal glucose processing", "effective, focused approach", "sodium-glucose cotransporter", "overall cardiovascular health" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1310, "imageuri": "https://productimages.withfloats.com/actual/665f0820c40ee9be019637c3.jpg", "tileimageuri": "https://productimages.withfloats.com/tile/665f0820c40ee9be019637c3.jpg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-04T12:27:09.955Z", "updatedon": "2026-03-13T05:48:27.403Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//glidapaflozin-10-/1310", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "GLIDAPAFLOZIN 10 ", "category": "DIABETIC RANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "665efdbd66170d1ff8cb13bf", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Dapaflozin 10 mg, Sitagliptin 100 mg & Metformin SR 500 mg", "description": "GLIDAPA 3D 10/100/500 SR \nDapaflozin 10 mg, Sitagliptin 100 mg & Metformin SR 500 mg\nIntroduction\nGLIDAPA 3D 10/100/500 SR is a sophisticated, multi-mechanism oral medication designed for the management of Type 2 diabetes. It combines Dapagliflozin (10 mg), Sitagliptin (100 mg), and Metformin (500 mg, sustained release), offering a robust, integrated approach to controlling high blood glucose levels.\n\nMechanism of Action\n\nDapagliflozin (10 mg): As an SGLT2 inhibitor, Dapagliflozin promotes the excretion of glucose through urine by blocking its reabsorption in the kidneys. This helps to lower blood sugar levels and also has benefits for weight loss and cardiovascular health.\nSitagliptin (100 mg): A DPP-4 inhibitor, Sitagliptin works by enhancing the body's own ability to lower blood glucose levels in response to meals. It does this by increasing the levels of incretin hormones, which affect the pancreas to produce more insulin and less glucagon.\nMetformin SR (500 mg): Metformin works primarily by reducing glucose production in the liver, improving insulin sensitivity, and lowering glucose absorption in the gut. The sustained-release (SR) formulation ensures a steady release over time, minimizing gastrointestinal side effects and maintaining more consistent blood sugar control.\nBenefits\nGLIDAPA 3D 10/100/500 SR provides a comprehensive treatment solution by addressing several key pathways in glucose metabolism, thereby reducing the risk of both hyperglycemia and associated complications. The combination of these three active substances in a single formulation enhances convenience and potentially improves adherence to treatment protocols.\n\nDosage and Administration\n\nDosage: The recommended starting dose depends on the patient’s current treatment regimen and their specific health profile. Adjustments should be made based on effectiveness and tolerability, under the guidance of a healthcare professional.\nAdministration: This medication should be taken once daily in the morning, with or without food. The tablet should be swallowed whole to maintain the sustained release of Metformin.\nSide Effects\nPossible side effects of GLIDAPA 3D 10/100/500 SR include urinary tract and genital infections (due to Dapagliflozin), nausea or a sore throat (from Sitagliptin), and digestive issues such as diarrhea or abdominal pain (common with Metformin). Most side effects are manageable and tend to decrease over time.\n\nConclusion\nGLIDAPA 3D 10/100/500 SR is a versatile and effective option for those managing Type 2 diabetes, offering triple-action treatment in one convenient medication. It targets various aspects of diabetes management, improves glycemic control, and enhances overall quality of life. Patients are advised to maintain regular follow-ups with their healthcare provider to optimize treatment outcomes and manage any side effects.\nFor further information:\nEMAIL: info@sterispharma.com / contact@sterispharma.com \n Order Now\n", "price": 539.0, "discountamount": 162.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "gut", "time", "life", "risk", "food", "body", "urine", "liver", "EMAIL", "Order", "meals", "500 mg", "nausea", "tablet", "patient", "ability", "kidneys", "morning", "response", "diarrhea", "pancreas", "guidance", "benefits", "adherence", "versatile", "excretion", "Conclusion", "sore throat", "Sitagliptin", "weight loss", "Adjustments", "combination", "information", "convenience", "Introduction", "sterispharma", "Metformin SR", "reabsorption", "sterisonline", "urinary tract", "CALL/WHATSAPP", "hyperglycemia", "Dapagliflozin", "less glucagon", "effectiveness", "starting dose", "abdominal pain", "steady release", "overall quality", "SGLT2 inhibitor", "various aspects", "Type 2 diabetes", "DPP-4 inhibitor", "Dapaflozin 10 mg", "effective option", "digestive issues", "glycemic control", "Most side effects", "sustained release", "incretin hormones", "regular follow-ups", "genital infections", "blood sugar levels", "glucose metabolism", "glucose absorption", "glucose production", "treatment outcomes", "single formulation", "diabetes management", "insulin sensitivity", "healthcare provider", "treatment protocols", "several key pathways", "Administration Dosage", "Possible side effects", "cardiovascular health", "triple-action treatment", "specific health profile", "three active substances", "healthcare professional", "associated complications", "GLIDAPA 3D 10/100/500 SR", "current treatment regimen", "one convenient medication", "high blood glucose levels", "robust, integrated approach", "gastrointestinal side effects", "consistent blood sugar control", "comprehensive treatment solution", "sustained-release (SR) formulation", "sophisticated, multi-mechanism oral medication" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1300, "imageuri": "https://productimages.withfloats.com/actual/665efdc0e874b19df8b5f4ce.png", "tileimageuri": "https://productimages.withfloats.com/tile/665efdc0e874b19df8b5f4ce.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-04T11:42:53.803Z", "updatedon": "2026-03-13T07:20:46.914Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//dapaflozin-10-mg-sitagliptin-100-mg-metformin-sr-500-mg/1300", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "GLIDAPA 3D 10/100/500 SR ", "category": "DIABETIC RANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "665ef5bda743fd235821deeb", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "gliclazide 80 mg metformin 500 mg", "description": "GLICLAGLAZE M 80 \ngliclazide (80 mg), metformin (500 mg)\nIntroduction\nGLICLAGLAZE M 80 is a specialized medication formulated for individuals diagnosed with Type 2 diabetes, aiming to enhance blood sugar regulation. This oral medication combines Gliclazide (80 mg) with Metformin (500 mg), two effective antidiabetic agents that provide a synergistic effect to control high blood sugar.\n\nMechanism of Action\n\nGliclazide (80 mg): Belonging to the sulfonylurea class, gliclazide works by increasing insulin secretion from the pancreatic beta cells. It promotes a decrease in blood glucose levels and enhances the action of insulin in the body. Additionally, Gliclazide improves blood flow and has protective effects against the vascular complications of diabetes.\nMetformin (500 mg): Metformin reduces hepatic glucose production and improves insulin sensitivity by enhancing peripheral glucose uptake, particularly in muscle cells. This action helps lower blood glucose levels without the risk of inducing hypoglycemia and is associated with a potential reduction in body weight.\nBenefits\nGLICLAGLAZE M 80 offers a robust approach to managing Type 2 diabetes by targeting different aspects of the disease. The combination of Gliclazide and Metformin in this medication helps to control blood sugar more effectively than either component alone, potentially lowering the patient's risk of diabetes-related complications.\n\nDosage and Administration\n\nDosage: The starting dose should be adjusted based on the patient’s previous medication regimen, effectiveness, and tolerability. Dose adjustments should be made based on glycemic control, as assessed by regular monitoring of blood glucose levels.\nAdministration: It is recommended to take GLICLAGLAZE M 80 with meals to maximize drug absorption and minimize potential gastrointestinal side effects.\nSide Effects\nPotential side effects of GLICLAGLAZE M 80 include gastrointestinal symptoms like nausea and diarrhea, which usually improve over time. The risk of hypoglycemia exists but is moderated by the inclusion of metformin.\n\nConclusion\nGLICLAGLAZE M 80 represents an effective treatment solution for managing Type 2 diabetes, combining two powerful antidiabetic agents to improve glycemic control and reduce the risk of diabetes complications. Patients should maintain regular consultations with their healthcare provider to tailor their treatment plan according to their specific needs, ensuring the best possible outcomes in diabetes management.\nFor further information:\nEMAIL: info@sterispharma.com / contact@sterispharma.com \n Order Now\n\n\n\n\n\n\n", "price": 137.0, "discountamount": 41.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "risk", "time", "Order", "meals", "EMAIL", "nausea", "500 mg", "Action", "patient", "disease", "diarrhea", "Benefits", "decrease", "Mechanism", "Metformin", "component", "inclusion", "Conclusion", "blood flow", "gliclazide", "individuals", "information", "body weight", "combination", "Introduction", "muscle cells", "tolerability", "sterispharma", "hypoglycemia", "sterisonline", "starting dose", "effectiveness", "CALL/WHATSAPP", "GLICLAGLAZE M", "treatment plan", "specific needs", "Type 2 diabetes", "oral medication", "robust approach", "drug absorption", "high blood sugar", "Dose adjustments", "glycemic control", "different aspects", "insulin secretion", "regular monitoring", "sulfonylurea class", "synergistic effect", "protective effects", "healthcare provider", "insulin sensitivity", "potential reduction", "diabetes management", "blood glucose levels", "regular consultations", "pancreatic beta cells", "Administration Dosage", "best possible outcomes", "blood sugar regulation", "Potential side effects", "specialized medication", "diabetes complications", "vascular complications", "gastrointestinal symptoms", "peripheral glucose uptake", "hepatic glucose production", "previous medication regimen", "effective treatment solution", "diabetes-related complications", "two powerful antidiabetic agents", "two effective antidiabetic agents", "potential gastrointestinal side effects" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1287, "imageuri": "https://productimages.withfloats.com/actual/665ef5c0ca75628a5853ff45.png", "tileimageuri": "https://productimages.withfloats.com/tile/665ef5c0ca75628a5853ff45.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-04T11:08:45.584Z", "updatedon": "2026-03-13T05:37:48.45Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//gliclazide-80-mg-metformin-500-mg/1287", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "GLICLAGLAZE M 80 ", "category": "DIABETIC RANGE", "tags": [ "gliclazide 80 mg metformin 500 mg tablet uses", "gliclazide 80 mg metformin 500 mg dosage for diabetes", "gliclazide metformin 80 mg 500 mg side effects", "gliclazide metformin 80 mg 500 mg how it works" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6abe4471401ae1a1106d67d9", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Bisoprolol 1.25mg", "description": "Bisoprolol 1.25mg is the smallest tablet strength of bisoprolol, a heart-selective beta-1 blocker. Doctors usually prescribe it to start treatment or to build up the dose gradually in people with high blood pressure, chronic stable heart failure, or fast heart rhythms. It suits older adults, people with mild heart failure, and anyone who reacts strongly to beta-blockers. The medicine slows the heartbeat and eases the force of each contraction, so the heart works less hard. BISOGARD 1.25 from Steris Healthcare Pvt. Ltd. comes in a strip pack of 15 tablets. It is a Schedule H medicine, so it must only be started, changed, or stopped on a doctor's advice.\n\nProduct Snapshot\n\nBrand: BISOGARD 1.25\nManufacturer/Marketer: Steris Healthcare Pvt. Ltd., a WHO-GMP and ISO-certified pharmaceutical company in India\nActive ingredient: Bisoprolol Fumarate 1.25mg\nForm: Tablet\nPack size: 15 tablets\nDrug class: Cardioselective beta-1 blocker\nLegal status: Schedule H (valid prescription required)\nAvailability: Through Steris Healthcare's authorized pharmacies and its B2B PCD franchise network across India\nWhat Is Bisoprolol 1.25mg?\n\nIf your doctor has just prescribed bisoprolol 1.25mg, you have been given the lowest dose on purpose. Bisoprolol is a cardioselective beta-1 blocker, meaning it acts mostly on receptors in the heart and has much less effect on the lungs and blood vessels. This is a major reason it is preferred over older, non-selective beta-blockers, especially for people who also have a mild breathing problem.\n\nThe 1.25mg tablet is not a “light” medicine for mild illness. It is a carefully chosen entry point. In heart failure, a weakened heart can struggle if its rate or pressure drops too quickly, so cardiologists follow a “start low, go slow” approach. Treatment begins at 1.25mg, the response is watched for one to two weeks, and the dose is raised step by step (commonly 2.5mg, 3.75mg, 5mg, 7.5mg, and up to 10mg) as the heart adapts. That is why BISOGARD 1.25 is often the first tablet a newly diagnosed heart failure patient takes.\n\nWhat Is Bisoprolol 1.25mg Used For?\n\nDoctors commonly prescribe this strength for:\n\nChronic heart failure (HFrEF): as the first step of dose titration in patients with a reduced ejection fraction, alongside ACE inhibitors/ARBs and diuretics\nHigh blood pressure: especially in older adults, people with low body weight, and those who are sensitive to blood-pressure-lowering drugs\nStable angina: to reduce the heart's oxygen demand and relieve chest discomfort\nAfter a heart attack: in selected patients, under a cardiologist's care\nHeart rate control in some arrhythmias: sometimes used off-label at a low dose to gently bring down a fast heart rate\n\nAt 1.25mg, bisoprolol is seldom meant as the long-term sole treatment for high blood pressure in an otherwise healthy adult. It is usually the first rung of a titration ladder, or a steady maintenance dose for patients who are unusually beta-blocker sensitive (older age, low body weight, or borderline low pressure or pulse).\n\nHow Does Bisoprolol Work?\n\nBisoprolol selectively blocks beta-1 adrenergic receptors, which are packed mainly into heart muscle. This leads to several effects:\n\nSlower heart rate: the heart has more time to fill and rest between beats\nGentler contractions: the heart muscle needs less oxygen and energy\nLess renin from the kidneys: this helps blood pressure fall gradually over time\nLower overall cardiac workload: a real advantage for a heart that already struggles to pump well, as in heart failure\nKey Benefits of BISOGARD 1.25\nA gentle starting dose, well suited to careful titration in frail or elderly patients\nHeart-focused action, with less effect on the lungs and peripheral blood vessels than non-selective beta-blockers\nOnce-daily dosing, which makes it easier to stay on treatment\nA guideline-recommended beta-blocker for HFrEF with well-established outcomes data [Reviewer note: insert specific outcome statistics/trial citation pending medical sign-off]\nMade by Steris Healthcare Pvt. Ltd. under WHO-GMP and ISO-certified standards\nDosage Guidance\nUsual starting dose (heart failure): 1.25mg once a day, preferably in the morning\nDose increases: typically every 1–2 weeks (2.5mg, 3.75mg, 5mg, 7.5mg, up to a maximum of 10mg daily), depending on how well you tolerate it and on your pulse and blood pressure\nHigh blood pressure (sensitive patients): 1.25mg to 5mg once daily, as set by your doctor\nHow to take it: at the same time every day, with or without food, swallowed whole with water\nIf you miss a dose: take it when you remember, unless the next dose is almost due. Never take a double dose.\nNever stop suddenly: abrupt withdrawal can cause a rebound rise in heart rate, blood pressure, or chest pain. The dose must be reduced gradually under medical supervision.\nIs It Better to Take Bisoprolol in the Morning or at Night?\n\nMost doctors advise a morning dose. Bisoprolol lowers pulse and blood pressure, and taking it early matches its action to your daytime activity. A night-time dose could add to the body's natural overnight dip in blood pressure and raise the chance of dizziness when getting up in the dark. Some people who feel tired during the day are told by their doctor to switch to the evening. Do not change your dosing time without your doctor's approval.\n\nSide Effects of Bisoprolol 1.25mg\n\nCommon side effects\n\nTiredness or fatigue\nDizziness or light-headedness, especially on standing quickly\nCold hands or feet\nSlow pulse (bradycardia)\nHeadache\nMild stomach upset (nausea, loose stools)\nDisturbed sleep\n\nSerious side effects (get medical help promptly)\n\nVery slow heartbeat or fainting\nIncreasing breathlessness or swollen legs/ankles, which may mean heart failure is worsening\nAllergic reaction: rash, swelling of the face or throat, trouble breathing\nCold, numb, or bluish fingers and toes\nWheezing or new breathing difficulty, particularly in people with asthma or COPD\nMood changes, low mood, or confusion\nWhat Are the Bad Side Effects of Bisoprolol?\n\nThe effects that need urgent attention are a dangerously slow pulse, fainting, signs of worsening heart failure (swelling, breathlessness), severe allergic reactions, and airway tightening in people with lung disease. These are uncommon at the 1.25mg dose, but anyone who notices them should seek medical help right away. [Reviewer note: specific incidence rates pending clinical/medical sign-off]\n\nSubstitutes & Comparable Beta-Blockers\nMolecule\tSelectivity\tTypical Use Case\nBisoprolol\tHighly cardioselective\tHeart failure titration, hypertension\nMetoprolol Succinate ER\tCardioselective\tHypertension, angina, heart failure\nAtenolol\tCardioselective (older agent)\tHypertension\nCarvedilol\tNon-selective with alpha-blocking action\tHeart failure (adds vasodilation)\nPropranolol\tNon-selective\tMigraine prevention, anxiety-related fast heartbeat, essential tremor\nPrecautions & Who Should Avoid Bisoprolol\nNot suitable for people with severe bradycardia, certain forms of heart block (unless a pacemaker is fitted), unstable or acutely decompensated heart failure, or severe uncontrolled asthma\nUse carefully in diabetes, because beta-blockers can hide the warning signs of low blood sugar\nTake care in peripheral vascular disease, as cold extremities or leg pain on walking may worsen\nNever stop it abruptly; always taper under a doctor's guidance\nTell your doctor about every medicine you use, especially other blood-pressure drugs, calcium channel blockers, and certain antiarrhythmics\nIn pregnancy and breastfeeding, use only if your doctor advises it after weighing benefits and risks\nIs Bisoprolol Safe for Kidneys?\n\nThe body clears bisoprolol through both the liver and the kidneys in roughly equal measure. It is generally considered safe for people with normal or mildly reduced kidney function. When kidney impairment is significant, drug levels in the blood can rise, so your doctor may lower the dose or monitor you more closely. Always tell your prescriber about any kidney disease before starting.\n\nIs Bisoprolol a High-Risk Medication?\n\nBisoprolol is not a narrow therapeutic index drug like tacrolimus or warfarin, where small dose differences matter greatly. Even so, it needs supervised use because it directly affects heart rate and blood pressure. The main dangers are stopping it suddenly, which can set off rebound cardiac events, and using it with certain existing rhythm disorders. Taken as prescribed and checked regularly, it has a long and reassuring safety record.\n\nDoes 1.25mg Bisoprolol Lower Blood Pressure?\n\nYes. Even the smallest dose measurably reduces heart rate and blood pressure by lightening the heart's workload and reducing renin-driven narrowing of blood vessels. At this strength the effect on blood pressure is fairly mild, which is exactly why it is a safe place to begin, especially for older adults or people starting heart failure treatment. The dose is then raised gradually to reach full benefit.\n\nFrequently Asked Questions\n\n1. What is 1.25 mg of bisoprolol used for?\nMainly as a low starting dose when building up treatment for chronic heart failure, and for high blood pressure in people who are very sensitive to beta-blockers, such as older adults.\n\n2. What are the bad side effects of bisoprolol?\nThe more serious ones are a very slow pulse, fainting, worsening heart failure signs (swelling, breathlessness), severe allergy, and breathing trouble in people with lung conditions.\n\n3. What are the common side effects of bisoprolol fumarate 1.25 mg tablets?\nTiredness, dizziness, cold hands and feet, mild headache, and a slightly slower pulse.\n\n4. Is it better to take bisoprolol in the morning or at night?\nMorning is usually preferred so its effect fits daytime activity, though your doctor may suggest evenings in some cases.\n\n5. What is the cost of bisoprolol?\nPrice depends on strength, pack size, and brand. Use the “Check Price” option above for current BISOGARD 1.25 pricing from Steris Healthcare.\n\n6. Does 1.25 mg bisoprolol lower blood pressure?\nYes, though only modestly at this dose. The dose is often stepped up over time.\n\n7. Is bisoprolol safe for kidneys?\nGenerally yes for normal or mildly reduced kidney function. People with significant kidney impairment need dose adjustment and monitoring.\n\n8. Is bisoprolol a high-risk medication?\nIt is not a narrow therapeutic index drug, but it must never be stopped suddenly and should be used under medical supervision because of its direct effect on the heart.\n\n9. Can I take bisoprolol 1.25mg for the rest of my life?\nMany people with chronic heart failure or hypertension do take bisoprolol long term, but the dose usually rises as tolerated. Your doctor should review it regularly.\n\n10. What happens if I miss a dose of bisoprolol?\nTake it when you remember, unless the next dose is nearly due. In that case skip the missed one. Never take two together.\n\n11. Can bisoprolol 1.25mg cause weight gain?\nIt is not commonly reported at this dose. Fluid retention linked to heart failure itself should be reported to your doctor.\n\n12. Is bisoprolol safe for diabetic patients?\nIt can be used, with care, because beta-blockers may hide warning signs of low blood sugar such as a racing heartbeat.\n\n13. Can I stop taking bisoprolol suddenly if I feel fine?\nNo. Stopping abruptly can cause a rebound rise in heart rate, blood pressure, or chest pain. Reduce the dose gradually under medical guidance.\n\n14. Does bisoprolol interact with other blood pressure medicines?\nYes. Combining it with other drugs that lower heart rate or pressure (such as calcium channel blockers) can cause a very low pulse or pressure. Tell your doctor about all your medicines.\n\n15. Is BISOGARD 1.25 available without a prescription?\nNo. Bisoprolol is a Schedule H medicine in India and needs a valid prescription.\n\n16. How long does it take for bisoprolol 1.25mg to start working?\nSome effect on heart rate appears within hours, but the full benefit for blood pressure or heart failure symptoms builds over several weeks of regular use.\n\n17. Can pregnant women take bisoprolol?\nOnly if clearly necessary and prescribed by a doctor, as it may affect the baby's heart rate and growth.", "price": 39.0, "discountamount": 12.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2501, "imageuri": "https://productimages.withfloats.com/actual/6abe4474c205678e0b16a23a.png", "tileimageuri": "https://productimages.withfloats.com/tile/6abe4474c205678e0b16a23a.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-10-01T11:30:57.88Z", "updatedon": "2026-10-01T11:30:57.88Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//bisoprolol-1-25mg/2501", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Bisogard 1.25", "category": "CARDIOLOGYRANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false } ], "hasmoreitems": false, "isapirequest": false, "totalresults": 27, "query": null, "floatingpoint": null }