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{ "products": [ { "_id": "6666b9a99f460208a41a62d2", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "tadalafil and dapoxetine tablets", "description": "DAPOXETINE LONG \nDAPOXITIME LONG is a potent combination tablet containing Tadalafil 10mg and Dapoxetine 30mg, crafted to tackle erectile dysfunction (ED) and premature ejaculation (PE) in men aged 18-64. This dual-action formula empowers men to achieve firmer erections, extend intercourse duration, and regain sexual confidence effectively. Designed for on-demand use, it offers a convenient solution for enhancing intimate experiences without daily dosing.​\n\nProduct Overview\nDAPOXETINE LONG stands out as an innovative pharmaceutical from Steris Healthcare, blending two clinically proven active ingredients into a single tablet. Tadalafil, a PDE5 inhibitor, relaxes penile blood vessels to boost blood flow during arousal, enabling strong, sustainable erections lasting up to 36 hours. Dapoxetine, a selective serotonin reuptake inhibitor (SSRI), modulates serotonin levels in the brain to delay ejaculation reflexes, providing better ejaculatory control.​\n\nThis synergistic pairing addresses the root causes of common male sexual challenges, making DAPOXITIME LONG ideal for men experiencing both ED and PE concurrently. Unlike single-ingredient treatments, it delivers comprehensive results in one easy-to-swallow tablet, typically taken 1-3 hours before anticipated sexual activity with water. Available through trusted pharmacies like Steris Online, it prioritizes discretion and efficacy for modern lifestyles.​\n\nKey Uses\nDAPOXITIME LONG primarily treats erectile dysfunction, where men struggle to attain or maintain an erection sufficient for satisfactory intercourse. It also effectively manages premature ejaculation, defined as ejaculation occurring sooner than desired, often within one minute of penetration.​\n\nBeyond core indications, the medication enhances overall sexual stamina, allowing couples to enjoy prolonged intimacy without performance pressure. Men with mixed symptoms find it particularly valuable, as it restores natural sexual rhythms and fosters deeper partner satisfaction. Clinical data supports its role in reducing related distress, making it a go-to for revitalizing bedroom dynamics.​\n\nMechanism of Action\nTadalafil inhibits phosphodiesterase type 5 (PDE5) enzymes, preventing cyclic guanosine monophosphate (cGMP) breakdown. This promotes smooth muscle relaxation in the corpus cavernosum, facilitating increased arterial inflow and reduced venous outflow for robust erections upon stimulation.​\n\nDapoxetine rapidly absorbs into the bloodstream, peaking within 1-2 hours, to elevate synaptic serotonin. This heightens sensory thresholds and prolongs intravaginal ejaculatory latency time (IELT) by 2-3 fold, as shown in phase 3 trials. The combination ensures Tadalafil's prolonged window aligns seamlessly with Dapoxetine's quick-onset control, optimizing dual benefits without interference.​\n\nKey Benefits\nSuperior Erection Quality: Tadalafil delivers reliable, long-lasting hardness, outperforming shorter-acting alternatives for spontaneous encounters.​\n\nExtended Intercourse Duration: Dapoxetine significantly boosts IELT, transforming brief encounters into fulfilling sessions averaging 3-4 times longer.​\n\nBoosted Confidence: Dual relief from ED and PE alleviates anxiety, enhancing self-esteem and relationship intimacy.​\n\nConvenience and Flexibility: On-demand dosing up to 36 hours of readiness eliminates rigid schedules, fitting busy lives seamlessly.​\n\nPartner Satisfaction: Improved performance leads to mutual pleasure, strengthening emotional bonds and reducing interpersonal distress.​\n\nThese advantages position DAPOXETINE LONG as a game-changer, backed by pooled efficacy data showing consistent improvements across demographics.​\n\nDosage and Administration\nTake one DAPOXITIME LONG tablet orally with a full glass of water 1-3 hours prior to sexual activity. Avoid grapefruit juice, heavy meals, or alcohol, as they may delay absorption or amplify side effects. Do not exceed one tablet per 24 hours or use more than once daily.​\n\nStart with the standard 10mg Tadalafil/30mg Dapoxetine dose; healthcare providers may adjust based on response and tolerance. Sexual stimulation remains essential, as the medication enhances natural physiology rather than initiating arousal independently. Store in a cool, dry place away from children.​\n\nPotential Side Effects\nCommon mild effects include headache, dizziness, nausea, flushing, nasal congestion, and indigestion, often resolving as the body adjusts. Dapoxetine-specific reactions like fatigue, dry mouth, or insomnia occur in about 10-20% of users initially.​\n\nLess frequent but notable are blurred vision from Tadalafil or back pain or diarrhea from Dapoxetine. Rare serious issues like priapism (prolonged erection >4 hours), sudden vision/hearing loss, or severe allergic reactions (rash, swelling) demand immediate medical attention. Most resolve without intervention, but monitoring is advised during early use.​\n\nPrecautions and Contraindications\nAvoid if allergic to either component or with nitrates, riociguat, alpha-blockers, or severe heart/liver/kidney issues. Consult a doctor for a history of low blood pressure, seizures, depression, glaucoma, or bleeding disorders. Not for women, children under 18, or men over 64 without guidance.​\n\nLifestyle tips: Stay hydrated, limit alcohol to prevent orthostatic hypotension, and disclose all medications to avoid interactions like with antifungals or HIV protease inhibitors. Regular checkups ensure safe, ongoing use.​\n\nConclusion\nDAPOXITIME LONG redefines male sexual wellness by merging Tadalafil's enduring erection support with Dapoxetine's precise ejaculation control, delivering unmatched performance gains. Men embracing this therapy report heightened satisfaction, confidence, and harmony in relationships, transforming intimacy from a concern to a strength. Prioritize professional consultation to tailor it to your health profile and unlock its full potential safely.​\n\n", "price": 355.0, "discountamount": 107.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "ED", "Call", "SSRI", "Email", "penis", "ORDER", "climax", "control", "WhatsApp", "erections", "Tadalafil", "blood flow", "information", "combination", "sterispharma", "sterisonline", "single tablet", "PDE5 inhibitor", "DAPOXITIME LONG", "Dapoxetine Long", "erectile dysfunction", "premature ejaculation", "comprehensive solution", "sexual health concerns", "selective serotonin reuptake inhibitor" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1636, "imageuri": "https://productimages.withfloats.com/actual/6666b9ac117f82c50b0351e7.png", "tileimageuri": "https://productimages.withfloats.com/tile/6666b9ac117f82c50b0351e7.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-10T08:30:33.181Z", "updatedon": "2025-12-18T07:57:35.962Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/tadalafil-and-dapoxetine-tablets/1636", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "DAPOXITIME LONG ", "category": "", "tags": [ "DAPOXITIME LONG", "Tadalafil (10mg)", "Dapoxetine (30mg)", "", "dapoxetine 30mg uses", "dapoxetine 30mg price in india", "", "dapoxetine 30mg uses in hindi", "", "dapoxetine 30mg side effects", "", "relaxes penile blood vessels to boost blood flow during arousal", "male sexual challenges.", "sexual activity .", "Partner Satisfaction." ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "69942f823b20a66d9dcf9458", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Indacaterol Maleate and Glycopyrronium Bromide", "description": "GLYCOPRESS INDUS™ is a modern dual bronchodilator therapy formulated with Indacaterol Maleate and Glycopyrronium Bromide, designed for the long-term maintenance treatment of chronic obstructive pulmonary disease (COPD). This advanced inhalation formulation combines two complementary mechanisms of action to deliver sustained airway relaxation, improved lung function, and enhanced breathing comfort.\n\nCOPD is a progressive respiratory condition characterized by airflow limitation, chronic inflammation, and episodes of breathlessness. Effective management requires consistent bronchodilation to keep the airways open and reduce daily symptoms. GLYCOPRESS INDUS™ addresses this need through a once-daily maintenance approach that targets airway narrowing through dual pharmacological pathways.\n\nManufactured under strict quality standards, GLYCOPRESS INDUS™ ensures reliable dosing, stability, and optimal pulmonary delivery when used with the recommended inhalation device. It is intended for regular use and not for the treatment of sudden breathing emergencies.\n\nComposition and Mechanism of Action\n\nGLYCOPRESS INDUS™ combines two long-acting bronchodilators:\n\n1. Indacaterol Maleate (Long-Acting Beta2-Agonist – LABA)\n\nIndacaterol stimulates beta2-adrenergic receptors located in the smooth muscles of the airways. Activation of these receptors causes the muscles to relax, resulting in bronchodilation. This effect:\n\nReduces airway resistance\n\nImproves airflow\n\nDecreases breathlessness\n\nSupports 24-hour bronchodilation\n\nIndacaterol is known for its rapid onset and prolonged duration of action, making it effective for once-daily therapy.\n\n2. Glycopyrronium Bromide (Long-Acting Muscarinic Antagonist – LAMA)\n\nGlycopyrronium blocks muscarinic receptors in the bronchial smooth muscles. These receptors normally respond to acetylcholine, which causes airway constriction. By inhibiting this response, glycopyrronium:\n\nPrevents bronchospasm\n\nReduces airway tightening\n\nPromotes sustained airway relaxation\n\nDual-Action Advantage\n\nThe combination of LABA and LAMA in GLYCOPRESS INDUS™ provides enhanced bronchodilation compared to either agent alone. While indacaterol actively relaxes airway muscles, glycopyrronium prevents them from tightening. This complementary action ensures comprehensive and sustained airway management.\n\nIndications and Uses\n\nGLYCOPRESS INDUS™ is indicated for:\n\nMaintenance treatment of chronic obstructive pulmonary disease (COPD)\n\nChronic bronchitis management\n\nEmphysema management\n\nLong-term airflow limitation therapy\n\nIt is important to understand that GLYCOPRESS INDUS™:\n\nIs not a rescue inhaler\n\nShould not be used for sudden acute bronchospasm\n\nIs not intended for primary asthma treatment unless prescribed by a physician\n\nPatients should always keep a short-acting bronchodilator available for emergency relief.\n\nKey Benefits of GLYCOPRESS INDUS™\n1. Once-Daily Dosing Convenience\n\nGLYCOPRESS INDUS™ is formulated for once-daily administration, improving adherence and simplifying treatment routines.\n\n2. Dual Bronchodilation for Superior Airway Control\n\nThe LABA + LAMA combination provides broader and more effective airway relaxation compared to single-agent therapy.\n\n3. Rapid Onset with Sustained Effect\n\nIndacaterol provides quick bronchodilation, while glycopyrronium maintains airway openness for up to 24 hours.\n\n4. Improved Lung Function\n\nRegular use can enhance lung performance parameters, such as improved airflow measurements and reduced air trapping.\n\n5. Reduced Breathlessness\n\nPatients may experience decreased shortness of breath during physical activities, leading to greater independence.\n\n6. Lower Frequency of COPD Exacerbations\n\nConsistent airway maintenance can help reduce the likelihood of flare-ups and hospital visits.\n\n7. Enhanced Quality of Life\n\nBetter breathing control contributes to improved sleep, increased exercise tolerance, and overall well-being.\n\nDosage and Administration\n\nGLYCOPRESS INDUS™ should be used exactly as prescribed by a healthcare professional.\n\nGeneral Administration Guidelines:\n\nUse once daily at the same time each day.\n\nInhale using the provided inhalation device.\n\nDo not swallow capsules (if capsule-based system).\n\nDo not exceed the recommended dose.\n\nFollow inhaler technique instructions carefully.\n\nProper inhalation technique is essential for effective drug delivery. Healthcare providers should demonstrate correct usage during initial prescription.\n\nPossible Side Effects\n\nWhile GLYCOPRESS INDUS™ is generally well tolerated, some individuals may experience side effects.\n\nCommon Side Effects\n\nDry mouth\n\nCough\n\nThroat irritation\n\nHeadache\n\nNasal congestion\n\nMild tremor\n\nDizziness\n\nThese symptoms are often mild and may diminish with continued use.\n\nCardiovascular Effects\n\nDue to the beta2-agonist component (indacaterol), some patients may experience:\n\nIncreased heart rate\n\nPalpitations\n\nMild fluctuations in blood pressure\n\nPatients with pre-existing heart conditions should consult their physician before starting therapy.\n\nAnticholinergic Effects (from Glycopyrronium)\n\nDifficulty urinating\n\nBlurred vision\n\nWorsening of narrow-angle glaucoma\n\nIndividuals with urinary retention or glaucoma should use caution.\n\nRare but Serious Reactions\n\nParadoxical bronchospasm (worsening breathing immediately after inhalation)\n\nSevere allergic reactions\n\nSignificant cardiac rhythm disturbances\n\nImmediate medical attention should be sought if severe reactions occur.\n\nPrecautions and Warnings\n\nBefore starting GLYCOPRESS INDUS™, inform your healthcare provider if you have:\n\nCardiovascular disease\n\nArrhythmias\n\nHypertension\n\nHyperthyroidism\n\nDiabetes\n\nSeizure disorders\n\nGlaucoma\n\nProstate enlargement\n\nKidney impairment\n\nDrug Interactions\n\nCaution is required when using:\n\nOther long-acting beta2-agonists\n\nOther anticholinergic medications\n\nBeta-blockers\n\nDiuretics\n\nCertain antidepressants (e.g., MAO inhibitors)\n\nAlways provide a complete list of medications and supplements to your healthcare provider.\n\nWho Should Use GLYCOPRESS INDUS™?\n\nGLYCOPRESS INDUS™ is ideal for:\n\nAdults with moderate to severe COPD\n\nPatients not adequately controlled on single bronchodilator therapy\n\nIndividuals seeking a once-daily maintenance inhaler\n\nPatients requiring dual bronchodilation for improved symptom control\n\nIt is not typically recommended for pediatric patients unless specifically directed by a healthcare professional.\n\nIntegrating GLYCOPRESS INDUS™ into COPD Management\n\nFor optimal results, GLYCOPRESS INDUS™ should be part of a comprehensive COPD management plan that includes:\n\nSmoking cessation\n\nPulmonary rehabilitation programs\n\nRegular physical activity\n\nBalanced nutrition\n\nScheduled medical follow-ups\n\nAdherence to therapy and routine monitoring significantly improve long-term outcomes.\n\nStorage Instructions\n\nStore at room temperature\n\nProtect from moisture and direct sunlight\n\nKeep in original packaging until use\n\nKeep out of reach of children\nConclusion\nGLYCOPRESS INDUS™ (Indacaterol Maleate + Glycopyrronium Bromide) is a powerful dual bronchodilator designed to provide sustained airway control in individuals living with chronic obstructive pulmonary disease. By combining a long-acting beta2-agonist and a long-acting muscarinic antagonist, it offers comprehensive bronchodilation through two complementary pathways.", "price": 703.0, "discountamount": 211.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2308, "imageuri": "https://productimages.withfloats.com/actual/69942f8410196f5f212c916f.png", "tileimageuri": "https://productimages.withfloats.com/tile/69942f8410196f5f212c916f.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-02-17T09:06:10.4Z", "updatedon": "2026-02-17T09:06:10.4Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/indacaterol-maleate-and-glycopyrronium-bromide/2308", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "GLYCOPRESS INDUS", "category": "ASTHMARANGE", "tags": [ "indacaterol maleate and glycopyrronium bromide inhalation powder dosage", "indacaterol maleate and glycopyrronium bromide dry powder inhaler use", "indacaterol maleate and glycopyrronium bromide COPD maintenance therapy", "indacaterol maleate and glycopyrronium bromide combination therapy side effects", "indacaterol maleate and glycopyrronium bromide unit dose inhalation capsules", "indacaterol maleate and glycopyrronium bromide nebulization instructions", "what is indacaterol maleate and glycopyrronium bromide used for", "how to use indacaterol maleate and glycopyrronium bromide inhaler", "buy indacaterol maleate and glycopyrronium bromide inhaler online" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69901185ae41895d8787c4d0", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Trazodone Hydrochloride", "description": "TORRANE 100 is a pharmaceutical formulation containing Trazodone Hydrochloride 100 mg as its active ingredient. This prescription medication belongs to the class of serotonin antagonist and reuptake inhibitors (SARIs), primarily designed to address major depressive disorder and associated sleep disturbances. TORRANE 100 represents a therapeutic solution that combines antidepressant properties with sedative effects, making it a versatile option for patients struggling with depression, particularly when accompanied by insomnia or anxiety symptoms.\nThe formulation comes in tablet form, designed for oral administration, and works by modulating serotonin levels in the brain. Unlike many traditional antidepressants, TORRANE 100 offers a unique mechanism of action that sets it apart in the treatment landscape, providing relief not only from depressive symptoms but also addressing sleep-related issues that often accompany mental health conditions.\nHow TORRANE 100 Works\nTORRANE 100 operates through a dual mechanism that influences brain chemistry. The active ingredient, Trazodone Hydrochloride, primarily inhibits the reuptake of serotonin—a neurotransmitter crucial for mood regulation—while simultaneously blocking certain serotonin receptors. This balanced approach helps restore emotional equilibrium and promotes a sense of well-being.\nThe medication's sedative properties stem from its antihistamine effects and alpha-adrenergic blocking activity, which contribute to its effectiveness in treating insomnia. When taken as prescribed, TORRANE 100 typically begins working within one to two weeks for depressive symptoms, though sleep improvements may be noticed sooner, often within the first few days of treatment.\nPrimary Uses and Applications\nTORRANE 100 is indicated for several therapeutic purposes:\nMajor Depressive Disorder: The primary indication for TORRANE 100 is the treatment of depression. Patients experiencing persistent sadness, loss of interest in daily activities, changes in appetite, or feelings of worthlessness may benefit from this medication under proper medical supervision.\nInsomnia Associated with Depression: One of the distinguishing features of TORRANE 100 is its effectiveness in treating sleep disturbances linked to depression. The medication helps patients fall asleep faster and maintain sleep throughout the night without causing the same dependency concerns associated with traditional sleeping pills.\nAnxiety Disorders: Healthcare providers sometimes prescribe TORRANE 100 off-label for anxiety disorders, as the medication's calming properties can help reduce excessive worry and tension.\nChronic Pain Management: In some cases, medical professionals utilize TORRANE 100 as part of a comprehensive pain management strategy, particularly for conditions involving neuropathic pain.\nKey Benefits of TORRANE 100\nThe therapeutic advantages of TORRANE 100 extend beyond simple symptom management:\nDual Action Formula: Unlike medications that target only depression or only sleep, TORRANE 100 addresses both concerns simultaneously, reducing the need for multiple prescriptions and simplifying treatment regimens.\nLower Addiction Potential: Compared to benzodiazepines and other sedative-hypnotics, TORRANE 100 carries a significantly lower risk of dependency, making it a safer long-term option for patients requiring ongoing sleep support.\nImproved Sleep Architecture: The medication promotes natural sleep patterns without severely disrupting REM sleep, which is essential for cognitive function and emotional processing.\nFewer Sexual Side Effects: Unlike many selective serotonin reuptake inhibitors (SSRIs), TORRANE 100 typically causes fewer sexual dysfunction issues, which can improve treatment adherence and quality of life.\nMood Stabilization: Patients often experience gradual improvement in overall mood, reduced irritability, and enhanced emotional resilience as treatment progresses.\nAnxiety Reduction: The anxiolytic properties help diminish racing thoughts and physical tension that often accompany depressive episodes.\nEnhanced Daily Functioning: By improving both mood and sleep quality, TORRANE 100 helps patients regain energy, concentration, and motivation to engage in daily activities and maintain relationships.\nPotential Side Effects\nWhile TORRANE 100 is generally well-tolerated, patients should be aware of possible adverse reactions:\nCommon Side Effects: Drowsiness and dizziness are the most frequently reported effects, particularly when initiating treatment or adjusting dosage. Dry mouth, blurred vision, constipation, and headaches may also occur but typically diminish as the body adjusts to the medication.\nOrthostatic Hypotension: Some patients experience a drop in blood pressure upon standing, leading to lightheadedness. Rising slowly from sitting or lying positions can help minimize this effect.\nGastrointestinal Disturbances: Nausea, vomiting, or changes in appetite may occur, though taking the medication with food often reduces these symptoms.\nWeight Changes: Some individuals may experience weight gain or loss during treatment.\nSerious but Rare Side Effects: Though uncommon, patients should seek immediate medical attention if experiencing priapism (prolonged painful erection), irregular heartbeat, severe dizziness, fainting, or signs of serotonin syndrome (confusion, rapid heartbeat, severe muscle stiffness).\nCardiac Considerations: TORRANE 100 may cause changes in heart rhythm, particularly in patients with pre-existing cardiac conditions.\nWithdrawal Symptoms: Abrupt discontinuation may lead to withdrawal effects; therefore, dosage should be tapered gradually under medical supervision.\nImportant Safety Considerations\nPatients should inform their healthcare provider about all medications, supplements, and herbal products they're taking, as TORRANE 100 can interact with numerous substances. Alcohol should be avoided, as it can intensify sedative effects. The medication may impair judgment and coordination, so caution is advised when driving or operating machinery until individual response is established.\nPregnant women, nursing mothers, and individuals with certain medical conditions should discuss the risks and benefits with their healthcare provider before starting TORRANE 100. Regular monitoring and follow-up appointments are essential to ensure optimal therapeutic outcomes and promptly address any concerns.\nConclusion\nTORRANE 100 represents a valuable therapeutic option for individuals battling depression, particularly when complicated by sleep disturbances. Its unique pharmacological profile offers comprehensive relief by addressing multiple symptoms simultaneously, potentially improving treatment adherence and quality of life. The medication's relatively favorable side effect profile, combined with lower addiction potential compared to traditional sleep aids, makes it an attractive choice for long-term management.", "price": 105.0, "discountamount": 32.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2304, "imageuri": "https://productimages.withfloats.com/actual/69901186e8395ed6920a6b9a.png", "tileimageuri": "https://productimages.withfloats.com/tile/69901186e8395ed6920a6b9a.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-02-14T06:09:09.093Z", "updatedon": "2026-02-14T09:19:42.439Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/trazodone-hydrochloride/2304", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "TORRANE 100", "category": "NEUROLOGY RANGE", "tags": [ "trazodone hydrochloride 100 mg tablet uses", "what is trazodone hydrochloride 100 mg used for", "trazodone hydrochloride 100 mg for sleep dosage", "trazodone hydrochloride 100 mg side effects in adults", "how long does trazodone hydrochloride 100 mg last", "trazodone hydrochloride 100 mg for anxiety reviews", "trazodone hydrochloride 100 mg weight gain risk", "trazodone hydrochloride 100 mg for insomnia effectiveness", "can I take trazodone hydrochloride 100 mg every night", "trazodone hydrochloride 100 mg liver side effects", "buy trazodone hydrochloride 100 mg online prescription", "trazodone hydrochloride 100 mg generic brand name", "trazodone hydrochloride 100 mg vs melatonin for sleep", "trazodone hydrochloride 100 mg vs mirtazapine" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6989adebfa5708ebdc6e8eee", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Clindamycin and Nicotinamide gel", "description": "VIGA BRIGHT Gel is an advanced dermatological formulation that combines two powerful active ingredients—Clindamycin and Nicotinamide—to deliver comprehensive acne treatment and skin brightening benefits. This scientifically formulated topical gel represents a breakthrough in skincare technology, addressing multiple skin concerns simultaneously. Designed for individuals struggling with acne, blemishes, hyperpigmentation, and uneven skin tone, VIGA BRIGHT Gel offers a dual-action approach that not only treats existing skin problems but also prevents future breakouts while promoting a naturally luminous complexion.\nThe unique synergy between Clindamycin, a proven antibiotic agent, and Nicotinamide, a form of Vitamin B3 known for its anti-inflammatory and skin-brightening properties, makes VIGA BRIGHT Gel a comprehensive solution for achieving healthier, clearer, and more radiant skin. This dermatologist-recommended formulation is suitable for various skin types and can be seamlessly integrated into daily skincare routines.\nUnderstanding the Active Ingredients\nClindamycin is a lincosamide antibiotic that works by inhibiting bacterial protein synthesis, effectively targeting the Propionibacterium acnes bacteria responsible for inflammatory acne. When applied topically, it penetrates the skin layers to combat bacterial growth at the source, reducing inflammation and preventing new acne lesions from forming.\nNicotinamide, also known as Niacinamide or Vitamin B3, is a water-soluble vitamin with remarkable skin-enhancing properties. It works at the cellular level to improve skin barrier function, reduce inflammation, regulate sebum production, and diminish hyperpigmentation. The combination of these two ingredients in VIGA BRIGHT Gel creates a powerful treatment that addresses acne while simultaneously improving overall skin quality and appearance.\nHow to Use VIGA BRIGHT Gel\nFor optimal results, proper application of VIGA BRIGHT Gel is essential. Begin by thoroughly cleansing your face with a gentle, non-comedogenic cleanser and pat your skin dry with a clean towel. Once your skin is completely dry, take a small amount of VIGA BRIGHT Gel—approximately a pea-sized quantity is sufficient for the entire face—and apply it evenly to the affected areas or as directed by your dermatologist.\nThe gel should be applied in a thin layer, avoiding the immediate eye area, lips, and any broken or irritated skin. Gently massage the gel into your skin using upward, circular motions until it is fully absorbed. For best results, use VIGA BRIGHT Gel once or twice daily, preferably in the evening before bedtime, as this allows the active ingredients to work effectively overnight when skin regeneration is at its peak.\nConsistency is crucial when using VIGA BRIGHT Gel. While some users may notice improvements within two to four weeks, optimal results typically appear after eight to twelve weeks of regular use. Always follow your healthcare provider's instructions regarding frequency and duration of application, and avoid using more product than recommended, as this will not accelerate results and may increase the risk of side effects.\nKey Benefits of VIGA BRIGHT Gel\nEffective Acne Treatment: The Clindamycin component powerfully combats acne-causing bacteria, significantly reducing inflammatory acne lesions including papules, pustules, and nodules. Regular use helps clear existing breakouts and prevents new ones from forming.\nSkin Brightening and Even Tone: Nicotinamide works to inhibit melanin transfer to skin cells, effectively reducing dark spots, post-inflammatory hyperpigmentation, and acne scars. This results in a noticeably brighter, more even-toned complexion over time.\nAnti-Inflammatory Action: Both active ingredients possess anti-inflammatory properties that calm redness, reduce swelling, and soothe irritated skin, making it particularly beneficial for sensitive, acne-prone skin.\nSebum Regulation: Nicotinamide helps regulate excessive oil production, addressing one of the primary causes of acne while preventing pores from becoming clogged with excess sebum.\nImproved Skin Texture: With continued use, VIGA BRIGHT Gel refines skin texture, minimizing the appearance of enlarged pores and creating a smoother, more refined complexion.\nEnhanced Skin Barrier Function: Nicotinamide strengthens the skin's natural protective barrier, improving moisture retention and protecting against environmental aggressors and irritants.\nReduced Acne Scarring: By addressing inflammation early and promoting healthy skin cell turnover, VIGA BRIGHT Gel helps minimize the formation of acne scars and gradually fades existing marks.\nNon-Comedogenic Formula: The gel-based formulation is lightweight and non-greasy, making it suitable for oily and combination skin types without clogging pores or causing additional breakouts.\nPotential Side Effects and Precautions\nWhile VIGA BRIGHT Gel is generally well-tolerated, some users may experience mild side effects, particularly during the initial weeks of use as the skin adjusts to the active ingredients.\nCommon Side Effects may include mild dryness, slight peeling or flaking, temporary redness at application sites, tingling or stinging sensation upon application, and mild itching. These effects are typically temporary and often subside as your skin acclimates to the treatment.\nLess Common Side Effects might involve contact dermatitis, increased skin sensitivity to sunlight, burning sensation, or excessive dryness. If these symptoms persist or worsen, discontinue use and consult your dermatologist.\nImportant Precautions: Always perform a patch test before full application, especially if you have sensitive skin. Apply a small amount to your inner forearm and wait 24 hours to check for adverse reactions. Avoid contact with eyes, mouth, nostrils, and mucous membranes; if accidental contact occurs, rinse thoroughly with water. Use a broad-spectrum sunscreen with SPF 30 or higher during daytime, as the treatment may increase sun sensitivity.\nPregnant or breastfeeding women should consult their healthcare provider before using VIGA BRIGHT Gel. Inform your dermatologist about all medications and skincare products you're currently using to avoid potential interactions. Do not use on broken, wounded, or eczematous skin without medical supervision.\nMaximizing Results with VIGA BRIGHT Gel\nTo achieve the best possible outcomes, incorporate VIGA BRIGHT Gel into a comprehensive skincare routine. Maintain consistency in application, stay hydrated by drinking adequate water throughout the day, and protect your skin from sun exposure with appropriate sunscreen. Avoid using harsh exfoliants or alcohol-based products that may cause additional irritation, and be patient—visible improvements in skin clarity and tone develop gradually with regular use.\nConclusion\nVIGA BRIGHT Gel represents a sophisticated approach to treating acne while simultaneously addressing pigmentation concerns and promoting overall skin health. The intelligent combination of clindamycin and Nicotinamide offers a comprehensive solution for individuals seeking clearer, brighter, and more radiant skin. By targeting acne-causing bacteria, reducing inflammation, regulating oil production, and brightening skin tone, this advanced formulation delivers multiple benefits in a single, convenient product.", "price": 125.0, "discountamount": 38.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2297, "imageuri": "https://productimages.withfloats.com/actual/6989aded9d6c96009e4b0b7d.png", "tileimageuri": "https://productimages.withfloats.com/tile/6989aded9d6c96009e4b0b7d.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-02-09T09:50:35.058Z", "updatedon": "2026-02-09T09:50:35.058Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/clindamycin-and-nicotinamide-gel/2297", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "VIGA BRIGHT Gel", "category": "Dermatology", "tags": [ "clindamycin and nicotinamide gel uses", "clindamycin nicotinamide gel benefits", "clindamycin nicotinamide gel how to use", "clindamycin nicotinamide gel side effects", "clindamycin and nicotinamide gel composition", "clindamycin nicotinamide gel for acne", "clindamycin nicotinamide gel for pimples", "clindamycin nicotinamide gel for acne scars", "clindamycin nicotinamide topical gel", "clindamycin nicotinamide gel 1 percent", "clindamycin nicotinamide gel tube", "what is clindamycin and nicotinamide gel", "is clindamycin nicotinamide gel safe", "how long does clindamycin nicotinamide gel take to work", "who should use clindamycin nicotinamide gel", "clindamycin with nicotinamide gel", "nicotinamide clindamycin acne gel" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "696f2a8662728a2493fefee6", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Rabeprazole Sodium and Cinitapride Capsules", "description": "Rabeprazole Sodium and Cinitapride Capsules (RABISTRUM CT): Complete Product Overview\n\nDigestive disorders such as acidity, gastroesophageal reflux disease (GERD), and functional dyspepsia have become increasingly common due to changing lifestyles, stress, irregular eating habits, and dietary choices. These conditions not only cause discomfort but can significantly affect daily life, sleep quality, and overall well-being. Rabeprazole Sodium and Cinitapride Capsules, marketed under the brand name RABISTRUM CT, offer an advanced and effective solution for managing acid-related and motility-related gastrointestinal disorders.\n\nRABISTRUM CT combines two proven medicines that work together to reduce stomach acid production and improve digestive movement, providing faster and longer-lasting relief from symptoms such as heartburn, bloating, nausea, and indigestion.\n\nWhat is RABISTRUM CT?\n\nRABISTRUM CT is a fixed-dose combination of:\n\nRabeprazole Sodium – a proton pump inhibitor (PPI)\n\nCinitapride – a prokinetic agent\n\nThis dual-action formulation is designed to address both the excess acid production and delayed gastric emptying that commonly occur in acid-peptic disorders. By targeting the root causes of digestive discomfort, RABISTRUM CT provides comprehensive relief and promotes better digestive health.\n\nUses of Rabeprazole Sodium and Cinitapride Capsules\n\nRABISTRUM CT is commonly prescribed for the treatment of:\n\nGastroesophageal reflux disease (GERD)\n\nAcid reflux and heartburn\n\nFunctional dyspepsia\n\nChronic gastritis\n\nPeptic ulcer disease\n\nBloating and post-meal fullness\n\nNausea and vomiting related to gastric motility issues\n\nThis combination is particularly beneficial for patients who experience persistent symptoms despite using acid-suppressing therapy alone.\n\nHow RABISTRUM CT Works\n\nRABISTRUM CT works through a dual-mechanism approach that provides effective and balanced digestive relief.\n\nRole of Rabeprazole Sodium\n\nRabeprazole Sodium belongs to the proton pump inhibitor class and works by:\n\nBlocking the final step of acid production in the stomach\n\nReducing excess gastric acid secretion\n\nAllowing healing of inflamed or damaged stomach and esophageal lining\n\nThis helps relieve symptoms such as burning sensation, acid regurgitation, and stomach pain.\n\nRole of Cinitapride\n\nCinitapride is a gastroprokinetic agent that works by:\n\nEnhancing stomach and intestinal motility\n\nImproving gastric emptying\n\nReducing bloating, nausea, and fullness\n\nStrengthening lower esophageal sphincter tone to prevent reflux\n\nTogether, these actions make RABISTRUM CT more effective than single-drug therapy in many digestive conditions.\n\nKey Benefits of RABISTRUM CT\n\nRABISTRUM CT offers several advantages for patients suffering from acid-related and motility disorders:\n\n1. Comprehensive Digestive Relief\n\nBy reducing acid production and improving gut movement, it treats the root cause of symptoms rather than providing temporary relief.\n\n2. Effective Management of GERD\n\nRABISTRUM CT helps control acid reflux, preventing heartburn and acid regurgitation, especially during nighttime.\n\n3. Reduces Bloating and Fullness\n\nCinitapride improves gastric emptying, making patients feel lighter and more comfortable after meals.\n\n4. Faster Symptom Improvement\n\nThe combined action leads to quicker relief compared to monotherapy.\n\n5. Improves Quality of Life\n\nRelief from chronic digestive discomfort helps improve appetite, sleep, and daily functioning.\n\nDosage and Administration\n\nThe dosage of RABISTRUM CT should be determined by a healthcare professional based on the patient’s condition and response to treatment. Generally:\n\nThe capsule is taken once daily, preferably before meals\n\nIt should be swallowed whole with water\n\nDo not crush or chew the capsule\n\nFor best results, patients should follow dietary advice, avoid trigger foods, and maintain regular meal timings.\n\nPossible Side Effects of RABISTRUM CT\n\nLike all medicines, Rabeprazole Sodium and Cinitapride Capsules may cause side effects in some individuals.\n\nCommon Side Effects\n\nHeadache\n\nDiarrhea\n\nNausea\n\nAbdominal discomfort\n\nDry mouth\n\nDizziness\n\nThese side effects are usually mild and tend to resolve as the body adjusts to the medication.\n\nLess Common but Serious Side Effects\n\nPersistent diarrhea\n\nAllergic reactions such as rash or itching\n\nIrregular heartbeat (rare)\n\nLong-term use may affect vitamin B12 absorption\n\nPatients should consult a doctor if side effects persist or worsen.\n\nPrecautions and Warnings\n\nRABISTRUM CT should be used under medical supervision\n\nPatients with liver disease should inform their doctor before use\n\nLong-term use should be monitored to avoid nutritional deficiencies\n\nPregnant and breastfeeding women should consult a healthcare provider\n\nAvoid alcohol as it may worsen stomach irritation\n\nWho Should Use RABISTRUM CT?\n\nRABISTRUM CT is suitable for:\n\nAdults with GERD or chronic acidity\n\nPatients with functional dyspepsia and bloating\n\nIndividuals experiencing delayed gastric emptying\n\nPatients who do not respond adequately to PPIs alone\n\nIt is not recommended for children unless prescribed by a doctor.\n\nLifestyle Tips to Support Treatment\n\nTo enhance the effectiveness of RABISTRUM CT:\n\nEat smaller, frequent meals\n\nAvoid spicy, fatty, and acidic foods\n\nDo not lie down immediately after eating\n\nReduce stress through relaxation techniques\n\nMaintain a healthy weight\n\nConclusion\n\nRabeprazole Sodium and Cinitapride Capsules (RABISTRUM CT) provide a powerful and well-balanced solution for managing acid-related and digestive motility disorders. By combining acid suppression with improved gastric movement, RABISTRUM CT offers faster relief, longer-lasting results, and improved quality of life for patients struggling with chronic digestive discomfort.\n\nWhen used as prescribed and supported by healthy lifestyle choices, RABISTRUM CT becomes a reliable and effective option for comprehensive gastrointestinal care.", "price": 185.0, "discountamount": 55.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2281, "imageuri": "https://productimages.withfloats.com/actual/696f2a88356da1ccb9841c5b.png", "tileimageuri": "https://productimages.withfloats.com/tile/696f2a88356da1ccb9841c5b.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-20T07:11:02.268Z", "updatedon": "2026-01-20T07:11:02.268Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/rabeprazole-sodium-and-cinitapride-capsules/2281", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "RABISTRUM CT", "category": "GASTROLOGYRANGE", "tags": [ "rabeprazole sodium and cinitapride capsules uses", "rabeprazole cinitapride capsule combination", "rabeprazole sodium cinitapride capsules price", "rabeprazole and cinitapride capsules dosage", "rabeprazole cinitapride capsules for acidity", "rabeprazole sodium cinitapride capsules benefits", "best rabeprazole sodium and cinitapride capsules in India", "rabeprazole cinitapride capsules for acid reflux", "rabeprazole sodium and cinitapride capsules for GERD", "rabeprazole cinitapride capsules for indigestion", "rabeprazole sodium and cinitapride capsules side effects", "rabeprazole cinitapride capsules for gas and bloating", "rabeprazole sodium cinitapride capsules for gastritis", "rabeprazole cinitapride capsules for delayed gastric emptying", "rabeprazole sodium and cinitapride capsules for heartburn", "rabeprazole cinitapride capsules for functional dyspepsia", "rabeprazole sodium and cinitapride capsules manufacturer India", "rabeprazole cinitapride capsules pharma company", "rabeprazole sodium and cinitapride capsules wholesale supplier", "rabeprazole cinitapride capsules third party manufacturing", "when to take rabeprazole and cinitapride capsules", "rabeprazole sodium and cinitapride capsules before food", "rabeprazole cinitapride capsules how it works", "rabeprazole sodium cinitapride capsules daily use", "rabeprazole cinitapride capsules for stomach pain" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69623e6c95697555dd1afd67", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Esomeprazole and Itopride", "description": "ESMOSTRUM IT: Comprehensive Product Guide\nProduct Overview\nESMOSTRUM IT is an advanced pharmaceutical formulation that combines two potent active ingredients—Esomeprazole and Itopride—to provide comprehensive relief from gastrointestinal disorders. This dual-action medication represents a significant advancement in the management of acid-related digestive conditions and motility disorders. By combining a proton pump inhibitor with a prokinetic agent, ESMOSTRUM IT addresses both the underlying causes and symptomatic manifestations of various digestive ailments, offering patients a complete therapeutic solution in a single, convenient dosage form.\nThe synergistic combination of Esomeprazole and Itopride makes ESMOSTRUM IT particularly effective for individuals suffering from gastroesophageal reflux disease (GERD), functional dyspepsia, and other conditions where both excessive acid production and impaired gastric motility contribute to discomfort and disease progression.\nActive Pharmaceutical Ingredients\nEsomeprazole\nEsomeprazole is the S-isomer of omeprazole and belongs to the class of medications known as proton pump inhibitors (PPIs). It works by specifically and irreversibly blocking the hydrogen-potassium adenosine triphosphatase enzyme system (the proton pump) located in the gastric parietal cells. This mechanism effectively reduces gastric acid secretion, providing sustained relief from acid-related symptoms and allowing damaged esophageal and gastric tissue to heal.\nItopride\nItopride is a prokinetic agent that enhances gastrointestinal motility through a dual mechanism of action. It acts as both a dopamine D2 receptor antagonist and an acetylcholinesterase inhibitor. By blocking dopamine receptors, it removes the inhibitory effect of dopamine on gastrointestinal motility, while its acetylcholinesterase inhibition increases acetylcholine levels, further promoting coordinated gastric contractions and improved gastric emptying.\nTherapeutic Uses and Indications\nESMOSTRUM IT is prescribed for a wide range of gastrointestinal conditions where both acid suppression and enhanced motility are therapeutically beneficial:\nGastroesophageal Reflux Disease (GERD)\nESMOSTRUM IT provides exceptional relief for patients suffering from GERD, a chronic condition where stomach acid frequently flows back into the esophagus. The esomeprazole component reduces acid production, while itopride improves the tone of the lower esophageal sphincter and accelerates gastric emptying, thereby reducing the frequency and severity of reflux episodes.\nFunctional Dyspepsia\nFor patients experiencing persistent or recurrent upper abdominal discomfort without an identifiable organic cause, ESMOSTRUM IT addresses multiple pathophysiological mechanisms. It relieves symptoms such as early satiety, postprandial fullness, epigastric pain, and bloating by normalizing gastric acid levels and improving gastric accommodation and emptying.\nPeptic Ulcer Disease\nESMOSTRUM IT aids in the healing of gastric and duodenal ulcers by creating an optimal healing environment through sustained acid suppression. The prokinetic action of itopride helps prevent stasis of gastric contents, which can exacerbate ulcer symptoms.\nNon-Ulcer Dyspepsia\nMany patients experience dyspeptic symptoms without evidence of ulceration. ESMOSTRUM IT effectively manages these symptoms by addressing both acid hypersecretion and delayed gastric emptying, two key factors in non-ulcer dyspepsia.\nGastroparesis-Related Symptoms\nIn conditions where gastric emptying is significantly delayed, the itopride component of ESMOSTRUM IT helps restore more normal gastric motility patterns, reducing associated symptoms like nausea, vomiting, and abdominal distension.\nKey Benefits and Advantages\nDual Mechanism of Action\nThe primary advantage of ESMOSTRUM IT lies in its comprehensive approach to gastrointestinal health. Rather than addressing only acid production or motility in isolation, this combination therapy tackles both aspects simultaneously, providing more complete symptom relief and better therapeutic outcomes.\nSuperior Acid Suppression\nEsomeprazole offers more consistent and prolonged acid suppression compared to many other acid-reducing medications. It provides sustained relief throughout the day and night, allowing patients to experience fewer breakthrough symptoms and better quality of life.\nEnhanced Gastric Motility\nThe itopride component specifically targets motility issues without crossing the blood-brain barrier significantly, meaning it provides prokinetic benefits with minimal central nervous system side effects. This results in improved gastric emptying, reduced bloating, and decreased feelings of fullness after meals.\nRapid Symptom Relief\nMany patients experience noticeable improvement in their symptoms within the first few days of treatment with ESMOSTRUM IT. The combination therapy addresses multiple symptom pathways simultaneously, leading to faster and more comprehensive relief.\nImproved Quality of Life\nBy effectively managing symptoms such as heartburn, regurgitation, nausea, bloating, and early satiety, ESMOSTRUM IT significantly enhances patients' daily functioning and overall well-being. Patients report better sleep quality, improved dietary tolerance, and reduced anxiety related to their digestive symptoms.\nConvenient Dosing\nThe combination of two active ingredients in a single formulation improves medication adherence by reducing pill burden. Patients appreciate the simplicity of taking one medication instead of multiple separate preparations.\nMucosal Healing Properties\nBeyond symptom relief, ESMOSTRUM IT promotes actual healing of damaged esophageal and gastric mucosa. The reduced acid environment created by esomeprazole allows inflamed and eroded tissue to regenerate properly.\nReduced Risk of Complications\nBy effectively controlling acid reflux and improving gastric emptying, ESMOSTRUM IT helps prevent potential complications of chronic GERD, such as esophageal strictures, Barrett's esophagus, and respiratory complications from aspiration.\nDosage and Administration\nESMOSTRUM IT should be taken exactly as prescribed by a healthcare professional. Typically, the medication is administered orally, preferably before meals to optimize its therapeutic effects. The standard dosing regimen usually involves once or twice daily administration, though individual requirements may vary based on the severity of the condition and patient response.\nThe medication should be swallowed whole with water and should not be crushed, chewed, or split, as this may affect the drug's release mechanism and therapeutic efficacy. Patients should maintain regular dosing schedules to ensure optimal acid suppression and motility enhancement throughout the day.\nSide Effects and Safety Considerations\nLike all medications, ESMOSTRUM IT may cause side effects in some individuals, though not everyone experiences them. Understanding potential adverse effects helps patients identify and report concerning symptoms promptly.\nCommon Side Effects\nGastrointestinal Effects: Some patients may experience diarrhea, constipation, abdominal pain, nausea, or flatulence, particularly during initial treatment. These effects are usually mild and often resolve as the body adjusts to the medication.\nHeadache: Mild to moderate headaches occur in a small percentage of patients and typically diminish with continued use.\nDizziness: Some individuals may experience lightheadedness or dizziness, particularly when standing up quickly.\nDry Mouth: Reduced saliva production may occur, leading to oral dryness and discomfort.\nLess Common Side Effects\nSkin Reactions: Rash, itching, or other dermatological manifestations may develop in sensitive individuals.\nSleep Disturbances: Some patients report insomnia or unusual dreams while taking the medication.\nIncreased Prolactin Levels: Itopride may cause mild elevation in prolactin levels, though clinical manifestations are rare.\nTaste Alterations: Changes in taste perception or metallic taste may occur temporarily.\nSerious Side Effects (Rare)\nWhile uncommon, certain serious adverse effects require immediate medical attention:\n\nSevere allergic reactions including difficulty breathing, facial swelling, or severe skin reactions\nSevere diarrhea that persists or contains blood\nIrregular heartbeat or palpitations\nMuscle weakness or pain\nSeizures or tremors\nSigns of liver problems including jaundice, dark urine, or persistent nausea\n\nLong-Term Considerations\nExtended use of proton pump inhibitors like esomeprazole has been associated with certain risks that patients should discuss with their healthcare providers:\n\nPotential reduction in calcium, magnesium, and vitamin B12 absorption\nSlightly increased risk of bone fractures with prolonged use\nPossible increased susceptibility to certain gastrointestinal infections\nRare cases of kidney problems\n\nRegular monitoring and periodic assessment by healthcare professionals help minimize these risks while maintaining therapeutic benefits.\nPrecautions and Contraindications\nPatients should inform their healthcare provider about all existing medical conditions, particularly liver disease, kidney problems, osteoporosis, low magnesium levels, or any gastrointestinal bleeding. ESMOSTRUM IT may interact with certain medications, including blood thinners, antifungals, HIV medications, and certain antibiotics. A complete medication review ensures safe and effective therapy.\nPregnant or breastfeeding women should only use ESMOSTRUM IT under strict medical supervision, as the safety profile in these populations requires careful consideration of potential risks and benefits.\nLifestyle Recommendations\nFor optimal therapeutic outcomes, patients taking ESMOSTRUM IT should complement their medication regimen with appropriate lifestyle modifications:\n\nAvoid trigger foods that exacerbate acid reflux, such as spicy foods, citrus, chocolate, caffeine, and alcohol\nMaintain a healthy body weight to reduce abdominal pressure\nEat smaller, more frequent meals rather than large portions\nAvoid lying down immediately after eating; wait at least two to three hours\nElevate the head of the bed if nighttime symptoms occur\nQuit smoking, as tobacco use significantly worsens reflux symptoms\nManage stress through relaxation techniques, as stress can exacerbate digestive symptoms\n\nConclusion\nESMOSTRUM IT represents a sophisticated and effective pharmaceutical solution for individuals struggling with complex gastrointestinal disorders involving both acid hypersecretion and impaired motility. By combining the powerful acid-suppressing capabilities of esomeprazole with the prokinetic benefits of itopride, this medication offers comprehensive symptom management that addresses the multifaceted nature of digestive disorders.", "price": 182.0, "discountamount": 54.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2273, "imageuri": "https://productimages.withfloats.com/actual/69623e6fd8491171373812e3.png", "tileimageuri": "https://productimages.withfloats.com/tile/69623e6fd8491171373812e3.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-10T11:56:28.061Z", "updatedon": "2026-01-17T05:39:38.96Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/esomeprazole-and-itopride/2273", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "ESMOSTRUM IT", "category": "GASTROLOGYRANGE", "tags": [ "esomeprazole and itopride tablets", "esomeprazole itopride combination tablet", "esomeprazole with itopride capsules", "esomeprazole itopride medicine uses", "esomeprazole itopride dosage", "what is esomeprazole and itopride used for", "esomeprazole and itopride combination meaning", "how esomeprazole and itopride work together", "benefits of esomeprazole and itopride tablets", "esomeprazole itopride for acidity and gas", "esomeprazole and itopride for acid reflux", "esomeprazole and itopride tablets price", "esomeprazole itopride tablets price in india", "best brand of esomeprazole and itopride", "esomeprazole itopride tablets manufacturers", "can esomeprazole and itopride be taken together", "is esomeprazole and itopride safe", "how long to take esomeprazole itopride" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6960c83f3056ad8a5a1aecba", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Cinnarizine and Domperidone Tablets ", "description": "CLANARIZINE DOM represents an advanced pharmaceutical combination that brings together two potent therapeutic agents—Cinnarizine and Domperidone—in a single convenient tablet formulation. This innovative combination medication addresses multiple aspects of vestibular disorders, motion sickness, and associated nausea and vomiting, providing comprehensive relief for patients suffering from these debilitating conditions. Manufactured under stringent quality control standards, CLANARIZINE DOM offers a synergistic approach to managing symptoms that significantly impact quality of life and daily functioning.The combination of Cinnarizine and Domperidone in CLANARIZINE DOM is based on sound pharmacological principles. While Cinnarizine works primarily on the vestibular system to reduce dizziness and vertigo, Domperidone acts as an effective antiemetic to control nausea and vomiting. Together, these two active ingredients provide more comprehensive symptom control than either agent alone, making CLANARIZINE DOM an excellent choice for patients experiencing vestibular disturbances accompanied by gastrointestinal symptoms.This combination therapy is particularly valuable because vertigo, dizziness, and motion sickness are frequently accompanied by nausea and vomiting. Patients suffering from these conditions often find that addressing only one aspect of their symptoms provides insufficient relief. CLANARIZINE DOM's dual-action formula tackles both the underlying vestibular dysfunction and the accompanying gastrointestinal distress, offering patients a more complete therapeutic solution that improves both comfort and functional capacity.Understanding the Active IngredientsCinnarizine is a calcium channel blocker with specific antihistaminic and vestibular suppressant properties. Unlike systemic calcium channel blockers used for cardiovascular conditions, Cinnarizine selectively acts on the blood vessels in the inner ear and brain, improving blood flow to these areas. This enhanced circulation helps reduce the frequency and severity of vertigo attacks while also preventing motion sickness. Cinnarizine also possesses mild antihistaminic effects that contribute to its anti-nausea properties, though this is not its primary mechanism of action.The medication works by blocking calcium channels in the vestibular system, which helps stabilize the sensory organs responsible for balance. By reducing the excessive stimulation of the vestibular apparatus, Cinnarizine decreases the sensation of spinning or imbalance that characterizes vertigo. Additionally, its vasodilatory effects improve microcirculation in the inner ear, which can be beneficial for conditions where reduced blood flow contributes to symptoms.Domperidone is a peripheral dopamine antagonist that acts primarily as a prokinetic and antiemetic agent. Unlike some antiemetic medications that cross the blood-brain barrier and cause sedation or extrapyramidal side effects, Domperidone works predominantly in the peripheral nervous system. It blocks dopamine receptors in the chemoreceptor trigger zone (CTZ) located outside the blood-brain barrier, effectively preventing nausea and vomiting without causing significant central nervous system effects.Domperidone also enhances gastrointestinal motility by promoting coordinated contractions of the stomach and upper small intestine. This prokinetic effect helps empty the stomach more efficiently, reducing feelings of fullness, bloating, and discomfort that often accompany vestibular disorders. By accelerating gastric emptying, Domperidone also reduces the likelihood of gastroesophageal reflux, which can exacerbate nausea in some patients.The combination of these two medications in CLANARIZINE DOM creates a complementary therapeutic effect. While Cinnarizine addresses the vestibular component of dizziness and vertigo, Domperidone manages the gastrointestinal symptoms that frequently accompany these conditions. This dual approach provides more comprehensive symptom relief and improves overall treatment outcomes compared to monotherapy with either agent alone.Clinical Applications and UsesCLANARIZINE DOM is indicated for a wide range of conditions characterized by vertigo, dizziness, and associated nausea. Understanding these clinical applications helps healthcare providers select appropriate candidates for this combination therapy.Vestibular Disorders: The primary indication for CLANARIZINE DOM includes various vestibular disorders that cause vertigo and imbalance. These conditions include Ménière's disease, benign paroxysmal positional vertigo (BPPV), vestibular neuritis, and labyrinthitis. Patients with these disorders experience episodes of spinning sensation, loss of balance, and often severe nausea. CLANARIZINE DOM helps reduce the frequency and intensity of vertigo attacks while controlling the accompanying gastrointestinal symptoms.Motion Sickness: CLANARIZINE DOM is highly effective for preventing and treating motion sickness, whether related to travel by car, boat, airplane, or amusement park rides. The medication can be taken prophylactically before travel or at the onset of symptoms. The combination is particularly useful for individuals who experience severe nausea and vomiting with motion sickness, as Domperidone provides powerful antiemetic effects that complement Cinnarizine's anti-motion-sickness properties.Migraine-Associated Vertigo: Many patients with migraines experience vestibular symptoms, including dizziness, vertigo, and motion sensitivity, either during migraine attacks or as independent episodes. CLANARIZINE DOM can help manage these vestibular manifestations of migraine, reducing both the vertigo and the nausea that often accompany migraine headaches.Post-Concussion Syndrome: Following head injuries, some patients develop persistent dizziness, balance problems, and nausea as part of post-concussion syndrome. CLANARIZINE DOM may provide symptomatic relief for these patients during their recovery period, though it should be used as part of a comprehensive treatment approach that includes rest, gradual return to activities, and vestibular rehabilitation when appropriate.Cerebrovascular Insufficiency: In older adults with reduced blood flow to the brain, symptoms such as dizziness, vertigo, tinnitus (ringing in the ears), and cognitive difficulties may develop. Cinnarizine's vasodilatory properties can improve cerebral circulation, potentially reducing these symptoms. The addition of Domperidone helps manage any associated nausea.Radiation-Induced or Chemotherapy-Induced Nausea: While not a primary indication, some healthcare providers use CLANARIZINE DOM as adjunctive therapy for patients undergoing cancer treatment who experience both nausea and dizziness. Domperidone's strong antiemetic properties are particularly valuable in this context.Key Benefits of CLANARIZINE DOMThe unique combination of Cinnarizine and Domperidone in CLANARIZINE DOM offers numerous advantages that make it a preferred choice for managing vestibular disorders and associated symptoms.Comprehensive Symptom Control: The primary benefit of CLANARIZINE DOM is its ability to address multiple symptoms simultaneously. Rather than requiring patients to take separate medications for vertigo and nausea, this combination provides unified treatment in a single tablet. This comprehensive approach improves symptom control across the full spectrum of vestibular disorder manifestations, from the spinning sensation to the gastrointestinal distress that often accompanies it.Improved Patient Compliance: Taking multiple medications can be burdensome, particularly for patients who feel dizzy or nauseated. CLANARIZINE DOM simplifies the treatment regimen by combining two medications in one tablet, making it easier for patients to adhere to their prescribed therapy. Better compliance translates to better outcomes, as consistent medication use is essential for managing chronic vestibular conditions.Synergistic Therapeutic Effects: The combination of Cinnarizine and Domperidone creates synergistic effects that enhance overall efficacy. While Cinnarizine reduces vestibular stimulation and improves inner ear blood flow, Domperidone prevents nausea and promotes gastric emptying. This dual action addresses both the cause and consequences of vestibular dysfunction, providing more complete relief than either medication alone.Reduced Central Nervous System Side Effects: Because Domperidone works primarily in the peripheral nervous system rather than crossing the blood-brain barrier extensively, CLANARIZINE DOM causes less sedation and fewer cognitive effects compared to some alternative antiemetic medications. This allows patients to maintain better alertness and function during treatment, which is particularly important for those who need to continue working or performing daily activities.Enhanced Quality of Life: Vertigo and chronic dizziness significantly impair quality of life, limiting mobility, social interactions, and occupational functioning. The nausea and vomiting that accompany these conditions add another layer of disability. By effectively controlling both vestibular and gastrointestinal symptoms, CLANARIZINE DOM helps restore patients' ability to engage in normal activities, improving overall life satisfaction and functional independence.Fast Onset of Action: CLANARIZINE DOM provides relatively rapid symptom relief, with many patients experiencing improvement within 30 minutes to 2 hours after taking the medication. This quick onset is particularly valuable for acute episodes of vertigo or when taking the medication prophylactically before situations that might trigger motion sickness.Suitable for Long-Term Use: For patients with chronic vestibular disorders requiring ongoing treatment, CLANARIZINE DOM is generally safe for extended use when properly monitored by a healthcare provider. The medication maintains its effectiveness over time without significant tolerance development, making it suitable for long-term symptom management.Improved Gastric Emptying: The prokinetic effects of Domperidone benefit not only nausea but also other gastrointestinal symptoms such as early satiety, bloating, and upper abdominal discomfort. Patients with vestibular disorders often develop gastroparesis or delayed gastric emptying secondary to their condition, and Domperidone addresses this issue effectively.Vascular Benefits: Cinnarizine's ability to improve blood flow to the inner ear and brain provides additional benefits beyond symptom control. Enhanced microcirculation may support healing and recovery in conditions where vascular insufficiency contributes to vestibular dysfunction.Side Effects and Safety ConsiderationsLike all medications, CLANARIZINE DOM can cause side effects, though not everyone experiences them. Understanding potential adverse effects helps patients recognize when to seek medical attention and allows healthcare providers to monitor therapy appropriately.Common Side Effects:The most frequently reported side effect of CLANARIZINE DOM is drowsiness or sedation, occurring in approximately 10-20% of patients. This effect is primarily attributable to Cinnarizine's antihistaminic properties. Patients should avoid driving or operating machinery until they know how the medication affects them. Taking the medication at bedtime can minimize daytime drowsiness for some patients.Dry mouth is another common side effect, affecting roughly 10-15% of patients. This occurs due to anticholinergic effects and can be managed by sipping water frequently, chewing sugar-free gum, or using saliva substitutes if severe. Maintaining good oral hygiene is important to prevent dental problems associated with reduced saliva production.Mild gastrointestinal symptoms, including constipation, abdominal discomfort, or changes in bowel habits, may occur. While Domperidone promotes gastric emptying, it can occasionally alter bowel motility. These effects are usually mild and resolve with continued use or dose adjustment.", "price": 55.0, "discountamount": 17.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2271, "imageuri": "https://productimages.withfloats.com/actual/6960c8410b0da405bc908e58.png", "tileimageuri": "https://productimages.withfloats.com/tile/6960c8410b0da405bc908e58.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-09T09:19:59.281Z", "updatedon": "2026-01-09T09:19:59.281Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/cinnarizine-and-domperidone-tablets-/2271", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CLANARIZINE DOM", "category": "NEUROLOGY RANGE", "tags": [ "cinnarizine and domperidone tablet uses", "what is cinnarizine & domperidone tablet used for", "cinnarizine domperidone combination medicine benefits", "how cinnarizine domperidone tablet works", "cinnarizine domperidone tablet for vertigo treatment", "cinnarizine domperidone tablet for inner ear problem", "cinnarizine domperidone tablet for balance disorder", "cinnarizine domperidone tablet for travel sickness", "cinnarizine domperidone tablet for gastric nausea", "cinnarizine & domperidone tablet price in india", "cinnarizine domperidone tablet brand name", "cinnarizine domperidone tablet manufacturer in india" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "694cf85408591c1173b54c2f", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Pregabalin Epalrestat and Methylcobalamin Tablets", "description": "EPSTATE ED represents an advanced pharmaceutical formulation that combines three powerful therapeutic agents: Pregabalin, Epalrestat, and Methylcobalamin. This innovative triple-combination medication is specifically designed to address the complex pathophysiology of diabetic neuropathy and neuropathic pain conditions. By integrating multiple mechanisms of action, EPSTATE ED offers a comprehensive approach to managing nerve-related complications that significantly impact the quality of life for millions of individuals worldwide.\nThe formulation addresses not only the symptomatic relief of neuropathic pain but also targets the underlying metabolic derangements that contribute to nerve damage progression. This multi-pronged therapeutic strategy makes EPSTATE ED particularly valuable for patients who require more than symptomatic management alone.\nUnderstanding the Active Components\nPregabalin: The Neuropathic Pain Modulator\nPregabalin serves as the cornerstone analgesic component in EPSTATE ED. This anticonvulsant medication works by binding to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. Through this mechanism, Pregabalin reduces the release of excitatory neurotransmitters including glutamate, norepinephrine, and substance P. This reduction in neurotransmitter release effectively dampens the abnormal neural signaling that characterizes neuropathic pain conditions.\nThe molecule demonstrates excellent bioavailability and rapid absorption, allowing patients to experience relief within a relatively short timeframe. Its efficacy in managing various neuropathic pain syndromes has been extensively documented in clinical trials, establishing it as a first-line agent for diabetic peripheral neuropathy, postherpetic neuralgia, and other chronic neuropathic pain conditions.\nEpalrestat: The Aldose Reductase Inhibitor\nEpalrestat represents a unique addition to the formulation, functioning as a selective aldose reductase inhibitor. In diabetic conditions, excess glucose is converted to sorbitol through the polyol pathway, with aldose reductase serving as the rate-limiting enzyme. The accumulation of sorbitol within nerve cells leads to osmotic stress, depletion of myoinositol, and subsequent nerve dysfunction.\nBy inhibiting aldose reductase, Epalrestat prevents this harmful sorbitol accumulation, thereby addressing one of the fundamental metabolic abnormalities responsible for diabetic neuropathy. This disease-modifying approach distinguishes EPSTATE ED from purely symptomatic treatments. Epalrestat has been particularly well-studied in Asian populations and has demonstrated the ability to improve nerve conduction velocities and reduce subjective neuropathic symptoms over time.\nMethylcobalamin: The Neurotropic Vitamin\nMethylcobalamin, the bioactive form of Vitamin B12, completes the therapeutic triad in EPSTATE ED. Unlike cyanocobalamin, which requires conversion in the body, methylcobalamin is immediately available for utilization in crucial biochemical processes. It plays an indispensable role in myelin synthesis, the protective sheath surrounding nerve fibers that enables proper signal transmission.\nThis coenzyme participates in methionine synthesis and is essential for maintaining the structural and functional integrity of neurons. Methylcobalamin also facilitates nerve regeneration and has demonstrated neuroprotective properties in various experimental models. For patients with diabetic neuropathy, who often exhibit Vitamin B12 deficiency (sometimes exacerbated by metformin therapy), supplementation with methylcobalamin addresses both nutritional deficits and supports nerve health at a fundamental level.\nClinical Applications and Uses\nEPSTATE ED is primarily indicated for the comprehensive management of diabetic peripheral neuropathy, a condition affecting approximately 50% of individuals with long-standing diabetes. The symptoms of this condition range from tingling sensations and burning pain to numbness and loss of protective sensation, which can lead to serious complications including foot ulcers and amputations.\nBeyond diabetic neuropathy, EPSTATE ED may be prescribed for various neuropathic pain syndromes where the combination of pain relief, metabolic correction, and nerve support proves beneficial. Patients experiencing chronic nerve pain resulting from metabolic disturbances, nutritional deficiencies, or structural nerve damage may find this combination particularly effective.\nThe medication is typically recommended for adults who have not achieved adequate symptom control with single-agent therapy or who would benefit from the synergistic effects of the three components. Healthcare providers may prescribe EPSTATE ED when a patient requires both immediate symptom relief and long-term disease modification.\nKey Benefits and Therapeutic Advantages\nComprehensive Multi-Mechanism Action\nThe primary advantage of EPSTATE ED lies in its multi-faceted approach to neuropathic conditions. Rather than addressing only pain symptoms, the formulation simultaneously tackles pain perception, underlying metabolic abnormalities, and nutritional support for nerve health. This comprehensive strategy may lead to superior outcomes compared to monotherapy approaches.\nEnhanced Pain Relief\nClinical evidence supporting Pregabalin's efficacy in neuropathic pain is substantial. Patients often report significant reductions in pain intensity, improved sleep quality due to decreased nocturnal pain, and enhanced ability to perform daily activities. The pain-relieving effects typically manifest within the first week of therapy and continue to improve with ongoing treatment.\nDisease Modification Potential\nUnlike purely symptomatic treatments, the inclusion of Epalrestat provides genuine disease-modifying potential. By targeting the polyol pathway, EPSTATE ED may slow the progression of nerve damage in diabetic patients. Long-term use may preserve nerve function and prevent the worsening of neuropathic symptoms, offering hope beyond mere symptom management.\nImproved Nerve Conduction and Function\nThe combination of metabolic correction through Epalrestat and neurotropic support via Methylcobalamin creates an environment conducive to nerve regeneration and functional improvement. Studies have demonstrated improvements in nerve conduction velocity parameters with similar combination therapies, suggesting potential restoration of nerve function rather than simple symptom masking.\nConvenience of Combination Therapy\nFor patients who would otherwise require multiple separate medications, EPSTATE ED offers the convenience of a single tablet containing all three therapeutic agents. This simplification of medication regimens improves compliance, reduces pill burden, and may enhance overall treatment outcomes.\nQuality of Life Enhancement\nThe cumulative effect of pain reduction, improved nerve function, and better metabolic control translates into meaningful quality of life improvements. Patients report better mobility, reduced interference of pain with daily activities, improved mood, and enhanced social functioning.\nPotential Side Effects and Safety Considerations\nCommon Side Effects\nAs with any pharmaceutical agent, EPSTATE ED may produce certain adverse effects. The most commonly reported side effects are primarily attributable to the Pregabalin component and include dizziness, somnolence, peripheral edema, dry mouth, blurred vision, weight gain, and difficulty with concentration or attention. These effects are generally mild to moderate and often diminish with continued therapy as the body adapts to the medication.\nGastrointestinal symptoms such as constipation or nausea may occur, though they are typically manageable with dietary modifications or symptomatic treatment. Some patients experience increased appetite leading to weight gain, which requires monitoring, particularly in diabetic individuals where weight management is crucial.\nSerious but Rare Adverse Events\nThough uncommon, certain serious adverse effects warrant immediate medical attention. These include allergic reactions manifesting as rash, itching, swelling, severe dizziness, or breathing difficulties. Pregabalin has been associated with rare cases of angioedema, which requires prompt discontinuation and medical intervention.\nMental health changes, including mood alterations, anxiety, depression, agitation, or suicidal thoughts, have been reported with Pregabalin use, particularly in individuals with pre-existing psychiatric conditions. Patients and caregivers should remain vigilant for behavioral changes and report them immediately to healthcare providers.\nDrug Interactions and Precautions\nEPSTATE ED may interact with other central nervous system depressants, including alcohol, opioids, benzodiazepines, and antihistamines, potentially intensifying sedation and cognitive impairment. Patients should inform their healthcare provider of all medications, supplements, and substances they consume.\nIndividuals with kidney impairment require dose adjustments since Pregabalin is primarily eliminated through renal excretion. Regular monitoring of renal function may be necessary during long-term therapy.\nSpecial Population Considerations\nPregnant or breastfeeding women should use EPSTATE ED only when clearly necessary and under strict medical supervision, as the safety profile in these populations has not been fully established. Elderly patients may be more susceptible to side effects, particularly dizziness and confusion, necessitating careful dose titration and monitoring.\nPatients should be advised against abrupt discontinuation of EPSTATE ED, as sudden cessation of Pregabalin may precipitate withdrawal symptoms including insomnia, nausea, headache, anxiety, and sweating. Gradual dose reduction under medical supervision is recommended when discontinuing therapy.\nDosage and Administration Guidelines\nThe appropriate dosage of EPSTATE ED is highly individualized and should be determined by a qualified healthcare professional based on the patient's specific condition, response to therapy, and tolerance. Typically, treatment begins with a lower dose that is gradually increased to achieve optimal therapeutic benefit while minimizing adverse effects.\nPatients should take EPSTATE ED exactly as prescribed, with or without food, at consistent times each day to maintain stable blood levels. Missing doses should be addressed by taking the forgotten dose as soon as remembered, unless it's nearly time for the next scheduled dose. Double dosing to compensate for missed doses is not recommended.\nRegular follow-up appointments allow healthcare providers to assess treatment efficacy, monitor for adverse effects, and make necessary dose adjustments. Patients should maintain open communication with their medical team regarding symptom improvement, side effects, and any concerns that arise during therapy.\nPatient Counseling and Lifestyle Recommendations\nMaximizing the benefits of EPSTATE ED extends beyond simply taking the medication. Patients should be counseled on complementary lifestyle measures that support neuropathy management. Maintaining optimal glycemic control remains paramount for diabetic patients, as blood sugar management directly impacts neuropathy progression regardless of medication.\nRegular physical activity, within individual capabilities, promotes circulation, supports nerve health, and may enhance the therapeutic effects of EPSTATE ED. Daily foot examinations become critical for diabetic patients to identify potential injuries early, preventing serious complications.\nNutritional optimization, including adequate intake of B vitamins, antioxidants, and essential nutrients, supports the neurotropic effects of Methylcobalamin. Avoiding alcohol and tobacco, both of which can exacerbate neuropathy, is strongly recommended.\nPatients should be cautioned about activities requiring alertness, such as driving or operating machinery, especially during the initial treatment phase when dizziness and somnolence may be more pronounced. These effects typically improve with continued therapy, but individual responses vary.\nConclusion\nEPSTATE ED represents a thoughtfully designed pharmaceutical formulation that addresses the multifaceted nature of diabetic neuropathy and neuropathic pain through its unique combination of Pregabalin, Epalrestat, and Methylcobalamin. This triple-action approach offers patients more than symptomatic relief—it provides genuine disease modification potential, nutritional support, and comprehensive nerve health optimization.\nThe synergistic effects of these three components create a therapeutic profile that is greater than the sum of its parts. While Pregabalin efficiently manages pain symptoms and improves quality of life in the short term, Epalrestat works to address underlying metabolic derangements that drive disease progression, and Methylcobalamin provides essential neurotropic support for nerve regeneration and function.\nFor patients struggling with the debilitating effects of neuropathic pain and diabetic neuropathy, EPSTATE ED offers renewed hope for better symptom control and potentially slowed disease progression. The convenience of combination therapy in a single tablet improves adherence and simplifies complex treatment regimens.\nHowever, EPSTATE ED is not without considerations. Potential side effects, though generally manageable, require awareness and monitoring. The medication is most effective when integrated into a comprehensive management plan that includes optimal glycemic control, lifestyle modifications, and regular medical supervision.\nUltimately, EPSTATE ED should be viewed as a valuable tool in the therapeutic arsenal against neuropathic conditions, best utilized under the guidance of knowledgeable healthcare professionals who can individualize treatment to each patient's unique needs and circumstances. With proper use, monitoring, and patient education, EPSTATE ED can significantly improve outcomes and quality of life for those affected by these challenging neurological conditions.", "price": 275.0, "discountamount": 82.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2253, "imageuri": "https://productimages.withfloats.com/actual/694cf859d25fa0b0657b1ac8.png", "tileimageuri": "https://productimages.withfloats.com/tile/694cf859d25fa0b0657b1ac8.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-25T08:39:48.947Z", "updatedon": "2026-01-10T06:06:36.677Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/pregabalin-epalrestat-and-methylcobalamin-tablets/2253", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "EPSTATE ED", "category": "NEUROLOGYRANGE", "tags": [ "regabalin, Epalrestat, and Methylcobalamin.neuropathic pain conditions.", "Pregabalin, Epalrestat, and Methylcobalamin.", "neuropathic pain.", "diabetic neuropathy.", "sorbitol within nerve cells leads to osmotic stress.", "Epalrestat and neurotropic support via Methylcobalamin creates an environment .", "mood alterations, anxiety, depression, agitation.", "supports the neurotropic effects of Methylcobalamin." ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6948f4ee5837f90c86a7e578", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Elagolix 200mg ", "description": "Eligolux200 contains 200 mg of elagolix per tablet and is manufactured by Steris Healthcare Pvt Ltd in India as a prescription medication in packs of 3x10 tablets. Elagolix acts as a potent gonadotropin-releasing hormone (GnRH) receptor antagonist, binding competitively to GnRH receptors in the pituitary gland to rapidly reduce estrogen and progesterone levels without the initial flare-\nup seen in agonists. This mechanism starves endometrial-like tissue outside the uterus of hormonal stimulation, shrinking lesions and easing inflammation.\n\nAdminister Eligolux200 orally, swallowed whole with water, with or without food, typically starting within 7 days of menstrual onset. Standard dosing for severe cases involves 200mg twice daily for up to 6 months, or 150mg once daily extended to 24 months, adjusted by physicians based on tolerance and response. Store in a cool, dry place away from moisture and light, keeping out of children's reach.\n\nPrimary Uses\nEligolux200 targets moderate to severe endometriosis-associated pain, including dysmenorrhea (painful periods), nonmenstrual pelvic pain, and dyspareunia (painful intercourse). Endometriosis affects millions globally, causing tissue similar to the uterine lining to grow ectopically, leading to chronic inflammation, adhesions, and scarring. By dosing flexibly, Eligolux200 suits patients needing stronger suppression for intense symptoms, reducing reliance on opioids or surgery.\n\nClinical trials like Elaris EM-I and EM-II showed 75% dysmenorrhea reduction and 50-60% nonmenstrual pain relief at 6-12 months. It also curbs heavy menstrual bleeding in uterine fibroids, offering dual benefits for overlapping conditions. Physicians prescribe it when first-line NSAIDs or oral contraceptives fail, prioritizing non-invasive symptom control.\n​\n\nKey Benefits\nEligolix in Eligolux200 delivers rapid pain relief, with significant improvements in daily pain scales within 3 months versus placebo. Women report 47% better composite pelvic pain scores, enhancing daily activities, work productivity, and intimacy. Quality-of-life metrics improve consistently over 24 weeks, including reduced fatigue and better emotional well-being.\n​\n\nUnlike injectables, its oral form and dose-dependent estrogen suppression allow titration—lower doses minimize hypoestrogenic effects while higher 200mg dosing tackles severe pain. Studies confirm amenorrhea in 25% of users early on, slashing bleeding days by up to 50%. Long-term data up to 12 months with add-back therapy sustains efficacy, preserving bone health better than monotherapy. Patients regain control, avoiding invasive laparoscopies and reclaiming normalcy.\n​\n\nBenefit\tEvidence from Trials'\tImpact on Patients\nDysmenorrhea Reduction:\t75% at 6 months \n​\tFewer missed workdays\nNonmenstrual Pain Relief:\t50-60% improvement \n​\tEnhanced mobility\nBleeding Control:\t14% bleeding days vs. 24% baseline \n​\tImproved hygiene, anemia prevention\nQuality of Life\tSustained over 24 weeks \n​\tBetter sleep, relationships\nPotential Side Effects\nCommon side effects of Eligolux200 mirror hypoestrogenic states: hot flashes, night sweats, headache, and nausea, each affecting about 10% of users. These often lessen as the body adjusts, with 69.5% overall adverse event rate over 24 weeks, mostly mild. Mood changes like irritability or depression occur less commonly, warranting mood monitoring.\n​\n\nBone mineral density (BMD) loss poses a key concern—200mg twice daily causes -1.5% to -2.4% drops at lumbar spine and hip after 6 months, attenuated with calcium/vitamin D or add-back therapy. Rare serious risks include suicidal thoughts, liver enzyme elevations, or allergic reactions like anaphylaxis. Discontinuation due to events stays low at 4-12%. No deaths are linked directly to treatment in trials.\n​\n\nSide Effect Category\tFrequency\tManagement\nVasomotor (Hot Flashes)\t9.9-10% \n​\tLifestyle cooling, dose adjustment\nNeurologic (Headache)\t9.9% \n​\tHydration, analgesics\nBone Loss\tUp to 2.4% at 6 months \n​\tDEXA scans, supplements\nMood Changes\tLess common \n​\tPsychiatric screening\nPrecautions and Contraindications\nAvoid Eligolux200 in pregnancy (risk of early loss), known osteoporosis, severe hepatic impairment, or with strong OATP1B1 inhibitors like cyclosporine or gemfibrozil. Women of childbearing age need effective non-hormonal contraception during and 28 days post-therapy, as it impairs recognition of pregnancy via amenorrhea. Not for pediatrics under 18 or geriatrics lacking data.\n\nScreen for depression history, liver function, and BMD before starting; monitor quarterly. Drug interactions abound with rifampin (reduces levels) or over 50 others like clarithromycin—inform physicians fully. Breastfeeding lacks safety data; weigh risks. Regular blood/urine tests track efficacy and safety.\n​\n\nDosage Guidelines\nInitiate Eligolux200 at 150mg daily for milder cases, escalating to 200mg BID for dyspareunia or severe pain, max 6 months at higher dose. Miss a dose? Take promptly unless near the next; never double. Duration caps at 24 months total, with liver-adjusted lower dosing. Pair with add-back for extended use to curb BMD loss.\n​\n\nPhysicians tailor based on response: 74-77% complete 6-month trials. Swallow intact; no crushing.\n​\n\nClinical Evidence\nPhase III trials (Elaris EM-I/II) randomized 1689 women, proving both doses superior to placebo for co-primary endpoints of dysmenorrhea and nonmenstrual pain. Open-label extensions to 24 weeks maintained gains. A 12-month study with add-back showed persistent relief and <1% additional BMD loss versus placebo. Real-world use echoes this, positioning Eligolix as first oral GnRH antagonist approved for endometriosis.\n​\n\nVersus relugolix, Eligolix offers comparable pelvic pain reduction with adjustable dosing. Indian brands like Eligolux200 align with global standards.\n​\n\nConclusion\nEligolux200 transforms endometriosis management, delivering substantial pain relief and functional gains through precise hormonal control. Balancing robust benefits against manageable risks like BMD monitoring empowers women toward symptom-free lives. Consult healthcare providers for personalized integration into care plans.\n", "price": 1000.0, "discountamount": 300.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2251, "imageuri": "https://productimages.withfloats.com/actual/694a2b9f403179ac7e958ef6.png", "tileimageuri": "https://productimages.withfloats.com/tile/694a2b9f403179ac7e958ef6.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-22T07:36:14.316Z", "updatedon": "2026-01-02T09:51:07.877Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/elagolix-200mg-/2251", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "ELIGOLUX 200", "category": "Gynaecology", "tags": [ "Elagolix Tablets 200mg", "Elagolix acts as a potent gonadotropin-releasing hormone.", "nonmenstrual pelvic pain.", "adhesions, and scarring", "preserving bone health better than monotherapy.", "avoiding invasive laparoscopies and reclaiming normalcy.", "pituitary gland to rapidly reduce estrogen and progesterone.", "tab elagolix 200mg", "elagolix 200mg.", "elagolix.", "elagolix 200.", "elagolix tablets", "elagolix tablets uses.", "elagolix 200 mg price.", "elagolix mechanism of action.", "elagolix 200 mg uses.", "tab elagolixtab elagolix." ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false } ], "hasmoreitems": false, "isapirequest": false, "totalresults": 27, "query": null, "floatingpoint": null }