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"description": "CONARIS T100 is a potent antifungal medication formulated with Terbinafine 250 mg and Itraconazole 100 mg. This combination tablet is designed to treat a wide range of fungal infections affecting the skin, nails, and other body parts. Terbinafine and Itraconazole work synergistically to eliminate fungi effectively by targeting their cell membranes and inhibiting growth, providing faster relief from symptoms such as itching, redness, scaling, and discomfort.\n\nFungal infections are common in humid climates and among individuals with compromised immunity, and medications like CONARIS T100 are essential for managing stubborn and recurrent infections. This combination therapy is often prescribed by dermatologists and healthcare professionals for moderate to severe fungal conditions.\n\nUses\n\nCONARIS T100 is used in the treatment of several fungal infections, including:\n\nDermatophytosis (Ringworm): Effective against infections of the skin, hair, and nails caused by dermatophytes.\n\nOnychomycosis (Nail Fungus): Helps in treating fungal infections of fingernails and toenails.\n\nTinea Infections: Treats tinea corporis, tinea cruris, and tinea pedis (athlete’s foot).\n\nCandidiasis: Useful in managing Candida infections affecting the skin and mucous membranes.\n\nRecurrent or Resistant Fungal Infections: Provides stronger antifungal action in cases not responsive to monotherapy.\n\nBenefits\n1. Broad-Spectrum Antifungal Action\n\nThe combination of Terbinafine and Itraconazole ensures effective activity against a wide variety of fungal species, including dermatophytes and yeasts.\n\n2. Faster Symptom Relief\n\nBy targeting fungi at multiple levels, CONARIS T100 helps relieve itching, redness, scaling, and discomfort more quickly than single-agent therapy.\n\n3. Treats Nail and Skin Infections\n\nTerbinafine penetrates nails effectively, while Itraconazole enhances the antifungal spectrum, making the combination ideal for nail and skin fungal infections.\n\n4. Reduces Recurrence\n\nCombination therapy decreases the risk of fungal infections returning by ensuring complete eradication of the pathogen.\n\n5. Convenient Dosage Form\n\nAvailable as an oral tablet, making it easy to administer and suitable for long-term treatment if prescribed.\n\nDosage\n\nAdults: Usually, one tablet of CONARIS T100 daily, preferably after meals, or as directed by a healthcare professional.\n\nTreatment Duration: Varies depending on the type and severity of infection; may range from 2 to 12 weeks for skin infections and longer for nail infections.\n\nImportant: Do not self-adjust dosage or stop treatment prematurely, as incomplete therapy can lead to recurrence or resistance.\n\nSide Effects\n\nCONARIS T100 is generally well tolerated when used as prescribed. Mild side effects may include:\n\nNausea or vomiting\n\nStomach upset or diarrhea\n\nHeadache\n\nDizziness\n\nSerious Side Effects (Rare)\n\nLiver enzyme elevation (monitoring recommended for long-term use)\n\nAllergic reactions such as rash, itching, or swelling\n\nSevere gastrointestinal discomfort\n\nConsult a healthcare provider immediately if you experience jaundice, persistent fatigue, or severe allergic reactions.\n\nPrecautions and Warning\n\nPregnancy and Breastfeeding: Use only if prescribed by a doctor; safety during pregnancy is not fully established.\n\nLiver or Kidney Disorders: Dose adjustment or close monitoring may be required.\n\nDrug Interactions: Inform your doctor about all medications, especially antifungals, statins, or anticoagulants.\n\nAvoid Self-Medication: Fungal infections may mimic other skin conditions, so proper diagnosis is essential.\n\nAlcohol Consumption: Avoid alcohol as it may increase liver toxicity risk.\n\nStorage: Store in a cool, dry place away from direct sunlight and out of children’s reach.\n\nConclusion\n\nCONARIS T100, containing Terbinafine 250 mg and Itraconazole 100 mg, is a reliable and effective treatment for a wide spectrum of fungal infections, including skin, nail, and mucosal infections. Its dual-action antifungal mechanism provides faster symptom relief, reduces recurrence, and improves overall patient outcomes.\n\nWhen used under medical supervision and following prescribed dosage, CONARIS T100 offers a safe and convenient option for managing both common and stubborn fungal infections, ensuring better skin and nail health and enhanced quality of life.",
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"name": "Terbinafine and Itraconazole Tablets 250/200mg",
"description": "CONARIS T200 is a potent antifungal combination tablet containing Terbinafine 250 mg and Itraconazole 200 mg, formulated to provide effective treatment for various fungal infections. Fungal infections of the skin, nails, and hair are common in India due to the hot and humid climate. These infections can cause itching, redness, scaling, and discomfort, affecting daily life and confidence.\n\nBy combining two powerful antifungal agents, CONARIS T200 targets fungal infections effectively, providing faster relief and improved recovery compared to monotherapy. Terbinafine works by inhibiting fungal cell growth, while Itraconazole disrupts fungal cell membrane formation, resulting in a comprehensive antifungal effect.\n\nUses\n\nCONARIS T200 is primarily prescribed for the management of:\n\nDermatophytosis (Ringworm, Tinea Infections)\nTreats fungal infections affecting skin, nails, and scalp.\n\nOnychomycosis (Fungal Nail Infection)\nHelps in eliminating nail fungus and promotes healthy nail growth.\n\nCandidiasis (Yeast Infections)\nEffective against mucocutaneous and superficial candidal infections.\n\nOther Superficial Fungal Infections\nUseful in treating skin infections caused by dermatophytes, yeasts, and other fungi.\n\nThis combination is particularly beneficial for chronic, resistant, or recurrent fungal infections.\n\nBenefits\n1. Broad-Spectrum Antifungal Activity\n\nThe dual action of Terbinafine and Itraconazole ensures effectiveness against a wide range of fungi, providing comprehensive treatment.\n\n2. Faster Symptom Relief\n\nPatients experience reduced itching, redness, scaling, and discomfort sooner than with single antifungal therapy.\n\n3. Promotes Healing\n\nSupports the restoration of healthy skin and nails, improving appearance and comfort.\n\n4. Reduces Recurrence\n\nThe combination therapy helps prevent fungal infections from returning, especially in chronic or resistant cases.\n\n5. Convenient Oral Administration\n\nOnce- or twice-daily tablet dosing improves patient compliance compared to topical treatments.\n\n6. Suitable for Adults\n\nFormulated for adult patients suffering from persistent fungal infections that require systemic therapy.\n\nDosage\n\nThe recommended dose of CONARIS T200 is usually one tablet once daily, or as directed by a physician.\n\nDuration of therapy depends on the type and severity of infection:\n\nSkin infections: Typically 2–4 weeks\n\nNail infections: May require 6–12 weeks or longer for full recovery\n\nImportant Instructions:\n\nSwallow the tablet whole with water.\n\nTake the medicine after food to reduce stomach upset.\n\nDo not skip doses and complete the full course even if symptoms improve.\n\nAlways follow the prescribing doctor’s instructions to ensure optimal results.\n\nSide Effects\n\nCONARIS T200 is generally well-tolerated, but some patients may experience mild side effects:\n\nNausea and vomiting\n\nStomach discomfort or indigestion\n\nHeadache\n\nDizziness\n\nSerious but Rare Side Effects\n\nLiver function disturbances\n\nAllergic reactions such as rash or swelling\n\nSevere gastrointestinal discomfort\n\nIf any unusual or severe symptoms appear, consult a healthcare professional immediately.\n\nPrecautions and Warning\n\nLiver and Kidney Disorders: Use with caution; liver function tests may be recommended during therapy.\n\nPregnancy and Breastfeeding: Consult your doctor before use; safety has not been fully established.\n\nDrug Interactions: Inform your doctor about other medications, particularly antacids, anticoagulants, or statins.\n\nAllergy: Avoid if allergic to Terbinafine, Itraconazole, or any other ingredient in the tablet.\n\nAlcohol Consumption: Limit alcohol intake, as it may increase the risk of liver-related side effects.\n\nConclusion\n\nCONARIS T200 (Terbinafine 250 mg + Itraconazole 200 mg) is an effective and trusted antifungal combination for the treatment of a variety of superficial and chronic fungal infections. By targeting fungi through dual mechanisms, it provides faster relief, promotes healing, and helps prevent recurrence. With proper dosing, adherence to medical advice, and monitoring for side effects, CONARIS T200 offers a comprehensive solution for adults dealing with persistent fungal infections, helping restore healthy skin, nails, and overall comfort.",
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"description": "PUMACOXIB PCM, featuring Polmacoxib 2mg and Paracetamol 325mg, delivers targeted relief from pain, inflammation, and fever associated with conditions like osteoarthritis and rheumatoid arthritis. This combination tablet works synergistically, with Polmacoxib inhibiting the COX-2 enzyme to curb inflammatory prostaglandins, while Paracetamol blocks pain signals in the brain. Patients often experience faster mobility and daily comfort from this dual-action formula.\n\nProduct Overview and Composition\nPUMACOXIB PCM stands out as a modern pharmaceutical solution crafted for effective management of acute and chronic pain issues. Each tablet contains precisely 2mg of Polmacoxib, a selective COX-2 inhibitor that precisely targets inflammation without broadly affecting other body processes, and 325mg of Paracetamol, a trusted analgesic and antipyretic. This balanced formulation ensures comprehensive coverage against discomfort from joint disorders, muscle strains, or post-injury swelling.\n\nThe medication's design emphasizes safety and efficacy, making it suitable for ortho patients and those with inflammatory conditions. Produced under high-quality standards, PUMACOXIB PCM offers a convenient single-dose approach to symptom control. Regular use as prescribed supports sustained joint health and reduces reliance on multiple drugs.\n\nKey Uses of PUMACOXIB PCM\nPUMACOXIB PCM proves highly effective for osteoarthritis, particularly in hip and knee joints, where it alleviates pain, stiffness, and swelling. Rheumatoid arthritis patients benefit from its ability to ease flare-ups, improving grip strength and movement. It also addresses general body aches, back pain, and muscle soreness from injuries or overuse.\n\nBeyond arthritis, the tablet manages post-surgical discomfort and inflammatory responses in conditions like tendonitis. For fever accompanying pain, such as in flu-related joint issues, Paracetamol component provides prompt temperature reduction. Healthcare providers often recommend it for short-term acute pain or longer-term chronic management under supervision.\n\nMajor Benefits and Advantages\nOne primary benefit of PUMACOXIB PCM lies in its rapid onset, delivering long-lasting pain relief that enhances daily activities without constant redosing. The selective COX-2 action of Polmacoxib minimizes gastrointestinal risks compared to traditional NSAIDs, allowing safer use for stomach-sensitive individuals. Combined with Paracetamol, it offers fever control alongside anti-inflammatory effects, creating a versatile tool for multifaceted symptoms.\n\nUsers report improved mobility and quality of life, with reduced joint stiffness enabling better exercise adherence and work productivity. Its lower side effect profile supports extended use in chronic cases, outperforming single-agent therapies in noninferiority studies against alternatives like etoricoxib combinations. Overall, PUMACOXIB PCM promotes holistic pain management with fewer disruptions to routine.\n\nFast-acting dual relief for pain and swelling.\n\nEnhanced joint flexibility for arthritis sufferers.\n\nSafer stomach profile for prolonged therapy.\n\nConvenient all-in-one tablet for busy lifestyles.\n\nPotential Side Effects and Precautions\nWhile generally well-tolerated, PUMACOXIB PCM may cause mild effects like nausea, headache, or dizziness in some users, often resolving without intervention. Rare risks include allergic reactions such as rash or swelling, requiring immediate medical attention. Liver concerns arise with Paracetamol overuse, so adherence to dosage—one to two tablets daily—remains crucial.\n\nAvoid alcohol to prevent liver strain, and consult doctors for kidney, liver, or heart conditions before starting. Pregnant or breastfeeding individuals should seek guidance, as should those on blood thinners or other medications. Monitoring ensures optimal safety, with most experiencing minimal issues at recommended levels.\n\nCommon Side Effects\tLess Common Risks\tManagement Tips\nNausea, dizziness \tAllergic rash, swelling \tTake with food; hydrate well\nHeadache \tLiver strain (overdose) \tFollow dosage; avoid alcohol\nStomach discomfort \tHeart-related (rare) \tConsult for pre-existing issues\nDosage Guidelines and Best Practices\nSwallow PUMACOXIB PCM whole with water, once or twice daily, adjusting per physician advice based on pain severity. It works with or without meals, though food may ease minor stomach upset. For acute pain, short courses suffice; chronic use needs regular check-ups.\n\nDo not exceed prescribed amounts to safeguard against Paracetamol accumulation. Store in a cool, dry place away from children. Integrating lifestyle changes like light exercise amplifies results.\n\nConclusion\nPUMACOXIB PCM with Polmacoxib 2mg and Paracetamol 325mg transforms pain management by blending potent anti-inflammatory and analgesic actions into one reliable tablet. Its benefits in reducing inflammation, easing pain, and boosting mobility make it ideal for arthritis and related woes, all while prioritizing a favorable safety profile. Choose PUMACOXIB PCM for empowered, discomfort-free living—consult your healthcare provider today to integrate it into your wellness plan.",
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"name": "Gabapentin and Lidocaine Hydrochloride Gel ",
"description": "Gabapentin and Lidocaine Hydrochloride is a specialized combination therapy primarily used to manage neuropathic pain—pain resulting from nerve damage, irritation, or dysfunction. This blend unites two highly effective agents: gabapentin, an anticonvulsant widely used for nerve-related pain, and lidocaine hydrochloride, a fast-acting local anesthetic that numbs nerve signals in targeted areas. Together, they deliver both systemic and localized pain relief, making the product ideal for patients seeking comprehensive control of chronic or acute neuropathic symptoms.\n\nThis combination may appear in different formulations, such as topical creams, patches, or oral gabapentin used alongside lidocaine topical therapy. The synergistic action makes it especially beneficial for individuals who do not achieve adequate relief from a single medication. By addressing pain through two different mechanisms—central nerve modulation (gabapentin) and peripheral nerve numbing (lidocaine)—this combination delivers a balanced approach to pain management with reduced need for stronger systemic medications.\n\nGabapentin works by calming overactive nerve signals in the central nervous system. It binds to calcium channels in the brain and spinal cord, reducing the abnormal firing responsible for neuropathic discomfort. Lidocaine, on the other hand, blocks sodium channels in peripheral nerves, preventing pain signals from traveling to the brain. Together, they create a powerful relief profile suitable for various nerve-related conditions.\n\nUses of Gabapentin and Lidocaine Hydrochloride\n\nThis combination is commonly recommended for patients dealing with complex nerve pain. Typical uses include:\n\n1. Neuropathic Pain\n\nIdeal for conditions such as:\n\nPeripheral neuropathy\n\nDiabetic neuropathy\n\nChemotherapy-induced neuropathy\n\nPost-surgical nerve pain\n\n2. Postherpetic Neuralgia (PHN)\n\nPatients recovering from shingles often experience burning, sharp, or stabbing nerve pain. Lidocaine patches offer localized relief, while gabapentin reduces the intensity of nerve signaling.\n\n3. Sciatica and Radicular Pain\n\nWhen pain radiates from the spine to the legs or arms due to nerve compression, this combination offers both deep and surface-level relief.\n\n4. Fibromyalgia\n\nGabapentin may reduce widespread nerve sensitivity, while lidocaine provides targeted relief in high-pain areas.\n\n5. Localized Musculoskeletal or Joint Pain With Nerve Involvement\n\nLidocaine can temporarily numb sensitive regions, while gabapentin addresses chronic nerve irritation.\n\nKey Benefits\n1. Dual-Action Pain Relief\n\nGabapentin works internally to stabilize nerve activity, while lidocaine provides immediate external numbing. This dual approach addresses pain from both ends.\n\n2. Reduced Need for Strong Systemic Painkillers\n\nMany patients experience significant relief without relying on opioids or sedatives.\n\n3. Rapid Onset from Lidocaine\n\nTopical lidocaine begins relieving pain within minutes by blocking peripheral nerve transmission.\n\n4. Long-Term Nerve Modulation from Gabapentin\n\nGabapentin’s central action builds gradually, offering sustained reduction of chronic nerve pain with consistent use.\n\n5. Versatile Application\n\nThe combination can be tailored to individual needs—oral gabapentin for long-term control and lidocaine patches or gel for targeted, immediate comfort.\n\n6. Improved Daily Function\n\nBy reducing constant nerve irritation, patients often regain mobility, sleep quality, and overall comfort.\n\nPossible Side Effects\nGabapentin Side Effects\n\nCommon:\n\nDizziness\n\nDrowsiness\n\nFatigue\n\nMild swelling in the legs\n\nCoordination problems\n\nLess common but important:\n\nMood changes\n\nBlurred vision\n\nDifficulty concentrating\n\nLidocaine Hydrochloride Side Effects\n\nCommon:\n\nSkin redness or irritation\n\nTemporary numbness\n\nMild burning or itching at application site\n\nRare but serious:\n\nAllergic reactions\n\nIrregular heartbeat (with excessive use)\n\nSystemic toxicity if large amounts are absorbed\n\nPatients should follow dosing instructions carefully and avoid applying lidocaine to broken skin unless instructed.\n\nConclusion\n\nThe combination of Gabapentin and Lidocaine Hydrochloride represents a powerful and effective solution for individuals struggling with neuropathic pain. By blending the internal nerve-calming effects of gabapentin with the fast-acting local numbing properties of lidocaine, this therapy covers multiple pain pathways simultaneously. It offers significant relief for conditions such as diabetic neuropathy, shingles-related pain, nerve compression syndromes, and chronic nerve-related disorders.",
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"description": "Sitagliptin 50 mg, Metformin Hydrochloride 1000 mg, and Glimepiride 2 mg is a triple-combination oral anti-diabetic medication formulated to achieve optimal blood sugar control in adults with Type 2 Diabetes Mellitus (T2DM). This unique blend brings together three complementary agents — Sitagliptin (a DPP-4 inhibitor), Metformin (a biguanide), and Glimepiride (a sulfonylurea) — that work through distinct mechanisms to enhance glucose regulation, improve insulin sensitivity, and support overall metabolic balance.\n\nThis advanced combination therapy is prescribed when monotherapy or dual therapy fails to achieve adequate glycemic control. It helps reduce both fasting plasma glucose (FPG) and postprandial glucose (PPG) levels, promoting stable long-term glycemic management.\n\nUses of Sitagliptin + Metformin + Glimepiride\n\nThis fixed-dose combination is primarily indicated for the management of Type 2 Diabetes Mellitus in adults. It is especially beneficial for patients whose blood sugar levels remain uncontrolled despite treatment with Metformin and Glimepiride or Metformin and Sitagliptin alone.\n\nIts main objectives include:\n\nControlling elevated blood glucose levels in adults with Type 2 diabetes\n\nReducing the risk of diabetes-related complications such as neuropathy, nephropathy, and cardiovascular diseases\n\nSupporting better insulin utilization by the body\n\nComplementing diet, exercise, and lifestyle modification to maintain optimal glycemic balance\n\nMechanism of Action\n\nEach component of this combination plays a vital role in maintaining blood sugar control:\n\nSitagliptin (50 mg) – A Dipeptidyl Peptidase-4 (DPP-4) inhibitor that enhances the activity of incretin hormones. These hormones stimulate insulin release and suppress glucagon production when blood glucose levels rise, thereby improving post-meal glucose control.\n\nMetformin Hydrochloride (1000 mg) – A biguanide that lowers glucose production in the liver and increases the body’s sensitivity to insulin. It also decreases intestinal glucose absorption, making it an essential first-line therapy in diabetes management.\n\nGlimepiride (2 mg) – A sulfonylurea that stimulates pancreatic beta cells to release more insulin, especially when blood glucose levels are high. It works synergistically with Metformin and Sitagliptin for more effective glycemic control.\n\nKey Benefits\n\nTriple Mechanism for Superior Control:\nBy combining three potent agents, the medication addresses multiple pathways of glucose regulation—insulin secretion, insulin sensitivity, and hepatic glucose output—resulting in comprehensive and consistent control of blood sugar levels.\n\nEffective Glycemic Stability:\nThe combination helps maintain target HbA1c levels and reduces both fasting and post-meal glucose spikes without significant weight gain when used with proper diet and exercise.\n\nReduced Risk of Diabetic Complications:\nLong-term blood sugar control minimizes the risk of complications such as kidney disease, vision problems, nerve damage, and heart conditions associated with uncontrolled diabetes.\n\nConvenient Fixed-Dose Formulation:\nCombining three medications into a single tablet simplifies dosing schedules, improves patient adherence, and reduces pill burden, which is crucial for long-term treatment success.\n\nImproved Insulin Efficiency:\nEnhances the body's natural insulin response and glucose metabolism, allowing for smoother daily energy levels and reduced fatigue associated with hyperglycemia.\n\nPossible Side Effects\n\nWhile this combination is generally well tolerated, some patients may experience side effects, especially at the beginning of therapy. Common and rare side effects include:\n\nHypoglycemia (low blood sugar): More likely when meals are skipped or during excessive physical exertion. Symptoms include sweating, dizziness, and rapid heartbeat.\n\nGastrointestinal disturbances: Such as nausea, vomiting, diarrhea, abdominal discomfort, or loss of appetite (mostly due to Metformin).\n\nHeadache or Weakness: Usually mild and transient.\n\nAllergic reactions: Rarely, rash or itching may occur.\n\nLactic Acidosis (rare but serious): A potential complication of Metformin, particularly in patients with kidney impairment or excessive alcohol consumption.\n\nWeight gain: Mild weight gain may occur due to Glimepiride’s insulin-enhancing effect.\n\nPrecautions:\n\nRegular monitoring of blood sugar levels and kidney function is essential.\n\nAvoid alcohol and consult a doctor before using this medicine if you have liver or kidney disease.\n\nThe medication should not be used in patients with Type 1 diabetes or diabetic ketoacidosis.\n\nConclusion\n\nThe combination of Sitagliptin 50 mg, Metformin Hydrochloride 1000 mg, and Glimepiride 2 mg represents a powerful and balanced therapy for adults with Type 2 Diabetes Mellitus, especially those requiring triple-drug intervention to achieve desired glycemic control. Its multi-targeted approach ensures effective management of both fasting and postprandial glucose levels, thereby improving long-term metabolic health and reducing the risk of complications.",
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"description": "TELAVINCE AF 25 is primarily indicated for:\n\nHypertension (High Blood Pressure): Effectively helps in lowering elevated blood pressure.\n\nCardiovascular Risk Reduction: Supports heart health and reduces the risk of heart attack, stroke, and other complications related to high blood pressure.\n\nPatients requiring combination therapy: Ideal for individuals who need more than one antihypertensive agent for optimal blood pressure control.\n\nMechanism of Action:\n\nTELAVINCE AF 25 combines two mechanisms for effective blood pressure management:\n\nTelmisartan: Blocks angiotensin II receptors, preventing blood vessel constriction and thereby reducing blood pressure.\n\n[AF Component, e.g., Amlodipine]: Relaxes blood vessels by inhibiting calcium entry into vascular smooth muscles, improving blood flow and reducing strain on the heart.\n\nThis dual-action combination provides better efficacy than single-drug therapy while maintaining a favorable safety profile.\n\nDosage and Administration:\n\nRecommended Dose: As prescribed by a healthcare professional, typically one tablet daily.\n\nRoute: Oral, with water.\n\nTiming: Can be taken with or without food, preferably at the same time each day.\n\nAdjustment: Dose may be adjusted based on individual response and tolerability.\n\nImportant: Always follow your doctor’s instructions. Do not change the dose or stop medication without medical advice.\n\nKey Benefits of TELAVINCE AF 25:\n\nEffective blood pressure control with dual-action therapy.\n\nReduces the risk of cardiovascular complications associated with hypertension.\n\nConvenient once-daily dosing for better patient adherence.\n\nWell-tolerated with minimal side effects.\n\nSuitable for long-term use under medical supervision.\n\nSafety and Precautions:\n\nInform your doctor if you have kidney disease, liver disease, or heart failure.\n\nPregnant or breastfeeding women should use only if recommended by a physician.\n\nAvoid excessive use of potassium-containing salt substitutes.\n\nRegular monitoring of blood pressure and kidney function is recommended.\n\nDo not combine with other angiotensin receptor blockers (ARBs) unless prescribed.\n\nPossible Side Effects:\n\nWhile generally well-tolerated, some patients may experience:\n\nDizziness or lightheadedness\n\nFatigue or weakness\n\nMild swelling of ankles or feet\n\nNausea or headache\n\nSeek immediate medical attention if you experience:\n\nSevere allergic reactions\n\nSwelling of face, lips, or throat\n\nDifficulty breathing\n\nStorage Instructions:\n\nStore in a cool, dry place away from sunlight.\n\nKeep out of reach of children and pets.\n\nDo not use after the expiry date mentioned on the package.\n\nWhy Choose TELAVINCE AF 25:\n\nDeveloped by Steris Healthcare Pvt. Ltd, a trusted pharmaceutical company.\n\nEnsures quality, safety, and efficacy in every tablet.\n\nDesigned for patient convenience with once-daily dosing.\n\nBacked by clinical research for effective hypertension management.\n\nDisclaimer:\n\nThe information provided here is for educational purposes only. TELAVINCE AF 25 should be used only under medical supervision. Consult your healthcare provider for personalized advice. Side effects may vary from person to person.\n\n",
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"description": "GLIMITERIS MV1 0.2 is an advanced fixed-dose combination (FDC) medication designed for adults with Type 2 Diabetes Mellitus (T2DM) who require more than lifestyle modifications or single/dual therapy to maintain optimal blood sugar levels. This innovative formulation brings together the power of three well-established antidiabetic agents—Glimepiride (1 mg), Voglibose (0.2 mg), and Metformin Hydrochloride SR (500 mg)—to provide comprehensive glycemic control.\n\nIt is particularly effective for patients struggling with postprandial hyperglycemia, fasting glucose regulation, and HbA1c reduction, making it a preferred choice in cases of poorly controlled diabetes.\n\n \n\nMechanism of Action\nThe therapeutic benefit of GLIMITERIS MV1 0.2 comes from the unique synergy of its three components, each targeting different aspects of glucose metabolism:\n\n1. Glimepiride (1 mg) – Sulfonylurea\nStimulates insulin secretion by activating pancreatic beta cells.\n\nProvides a long-lasting effect with comparatively lower hypoglycemia risk than older sulfonylureas.\n\nHelps reduce both fasting and postprandial glucose levels.\n\n2. Voglibose (0.2 mg) – Alpha-Glucosidase Inhibitor\nDelays the breakdown and absorption of carbohydrates in the intestine.\n\nMinimizes post-meal glucose spikes (PPBG).\n\nActs locally in the gut and has minimal systemic absorption, which reduces systemic side effects.\n\n3. Metformin Hydrochloride SR (500 mg) – Biguanide\nDecreases hepatic glucose production (gluconeogenesis).\n\nImproves peripheral insulin sensitivity, enhancing glucose uptake in muscles.\n\nDoes not cause hypoglycemia on its own.\n\nThe sustained-release (SR) formulation ensures extended control and reduces gastrointestinal side effects.\n\n \n\nIndications\nGLIMITERIS MV1 0.2 is indicated for:\n\nAdults with Type 2 Diabetes Mellitus.\n\nPatients inadequately controlled with monotherapy or dual therapy.\n\nManagement of fasting and postprandial hyperglycemia.\n\nLong-term HbA1c reduction as part of a comprehensive diabetes care plan.\n\n \n\nKey Benefits\n✅ Comprehensive Blood Sugar Control – Acts on fasting, post-meal, and long-term HbA1c levels.\n✅ Postprandial Spike Management – Voglibose effectively controls carbohydrate-induced sugar surges.\n✅ Reduced Pill Burden – Combines three medicines into a single tablet.\n✅ Lower Hypoglycemia Risk – Metformin and Voglibose balance out Glimepiride’s insulin-secreting effect.\n✅ Weight Management Support – Metformin may promote modest weight loss or prevent weight gain.\n✅ Improved Tolerability – SR formulation of Metformin enhances gastrointestinal comfort.\n\n \n\nDosage and Administration\nRecommended dose: One tablet once or twice daily with meals, or as directed by the physician.\n\nAdministration tips:\n\nTake with the first bite of a main meal to maximize Voglibose’s effect.\n\nSwallow whole with water; do not crush or chew the SR tablet.\n\nDose adjustments: Based on blood sugar monitoring, clinical response, and renal/hepatic function.\n\n \n\nContraindications\nGLIMITERIS MV1 0.2 is not suitable for patients with:\n\nType 1 diabetes or diabetic ketoacidosis.\n\nSevere renal impairment (eGFR <30 mL/min/1.73 m²).\n\nHepatic dysfunction.\n\nSevere gastrointestinal diseases.\n\nHistory of lactic acidosis.\n\nHypersensitivity to Glimepiride, Voglibose, or Metformin.\n\nPregnancy and lactation (unless strictly advised by a physician).\n\n \n\nWarnings and Precautions\nHypoglycemia: Risk is higher when combined with other antidiabetics or with missed meals.\n\nLactic Acidosis: A rare but life-threatening effect of Metformin—renal function monitoring is essential.\n\nGI Side Effects: Voglibose and Metformin may cause bloating, flatulence, or diarrhea (usually temporary).\n\nVitamin B12 Monitoring: Long-term Metformin use may reduce B12 absorption.\n\nLiver and Kidney Function: Regular monitoring is recommended for safe long-term use.\n\n \n\nAdverse Effects\nCommon:\nGlimepiride: Mild hypoglycemia, dizziness, slight weight gain.\n\nVoglibose: Gas, abdominal discomfort, mild diarrhea.\n\nMetformin SR: Nausea, bloating, metallic taste, loose stools.\n\nRare but Serious:\nLactic acidosis (from Metformin).\n\nSevere hypoglycemia (especially if meals are skipped).\n\nAllergic reactions such as rash, itching, or swelling.\n\nElevated liver enzymes.\n\nSeek medical attention if symptoms such as rapid breathing, confusion, severe fatigue, or muscle pain occur.\n\n \n\nDrug Interactions\nIncreased hypoglycemia risk: With insulin, beta-blockers, and sulfonylureas.\n\nReduced Metformin efficacy: With corticosteroids, estrogens, and diuretics.\n\nLactic acidosis risk: Higher with alcohol or iodinated contrast agents. ",
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