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"description": "CARDULES ISMN SR 60 delivers Isosorbide Mononitrate IP 60mg in a sustained-release tablet form, designed for long-term prevention of angina in patients with coronary artery disease. Produced by Steris Healthcare Pvt Ltd, this formulation ensures steady drug release over 12-24 hours, optimizing cardiovascular protection with once-daily dosing convenience. It supports heart health by enhancing blood flow without the peaks and troughs of immediate-release options.\n\nProduct Overview\nCARDULES ISMN SR 60 contains Isosorbide Mononitrate IP 60mg per sustained-release tablet, a pure nitrate metabolite that bypasses first-pass liver metabolism for consistent bioavailability. The SR technology employs a polymer matrix to gradually liberate the active ingredient, maintaining therapeutic plasma levels throughout the day and minimizing tolerance development associated with frequent dosing. Available in strips of 10 tablets, it features a film-coated exterior for easy swallowing and gastro-resistant properties to protect against stomach acid degradation.\n\nThis higher 60mg strength suits patients requiring intensified prophylaxis after initial titration from lower doses like 30mg or 40mg. It integrates seamlessly into comprehensive cardiac regimens alongside beta-blockers, statins, or aspirin, under cardiologist supervision. Quality manufacturing adheres to IP standards, ensuring purity above 99% with low impurity profiles for safety in chronic use.\n\nKey Uses\nCARDULES ISMN SR 60 primarily prevents chronic stable angina pectoris by dilating coronary arteries and reducing myocardial oxygen demand during exertion. Patients experience fewer episodes of chest tightness, pressure, or discomfort triggered by physical activity, stress, or cold exposure.\n\nIt manages coronary artery disease (CAD) by improving collateral circulation and easing ischemia in narrowed vessels. Often prescribed post-angioplasty or alongside lifestyle modifications, it stabilizes symptoms for enhanced daily functioning.\n\nAdditionally, it supports adjunctive therapy in congestive heart failure or post-myocardial infarction recovery, where vasodilation unloads the heart. Not for acute attacks—use sublingual nitroglycerin instead—but vital for long-term risk reduction.\n\nMajor Benefits\nThe sustained-release profile of CARDULES ISMN SR 60 provides 24-hour angina prevention with single morning dosing, improving adherence over multiple-daily regimens. This steady vasodilation lowers preload via venous pooling and afterload via arterial relaxation, cutting oxygen consumption by up to 20-30% during stress.\n\nPatients report increased exercise tolerance, with treadmill tests showing delayed onset of ST-segment depression. Enhanced myocardial perfusion boosts energy levels, enabling return to work, hobbies, or family activities without fear of sudden symptoms.\n\nCompared to shorter-acting nitrates, tolerance buildup is slower due to a nitrate-free interval built into once-daily use. Cost-effective at higher strengths, it reduces overall healthcare visits and hospitalization risks from unstable angina.\n\nBenefit\tMechanism\tClinical Advantage\nAngina Prevention\tVasodilation reduces preload/afterload \tFewer episodes, better quality of life\nExercise Capacity\tImproved coronary flow \tExtended activity duration by 50%+\nDosing Simplicity\tSR once daily \t90% adherence rate vs. multiple doses\nHeart Protection\tLowers ischemia risk. \tReduced MI recurrence\nPotential Side Effects\nCommon effects include headache (orthostatic or throbbing), especially in the first week, resolving with hydration and dose acclimation—acetaminophen helps manage it. Dizziness, lightheadedness, or postural hypotension may occur; rise slowly from sitting.\n\nGastrointestinal upset like nausea or flushing affects 5-10% initially. Avoid alcohol or PDE5 inhibitors (e.g., sildenafil) to prevent severe hypotension.\n\nRarely, reflex tachycardia, rash, or methemoglobinemia arises; monitor liver enzymes in prolonged use. Contraindicated in severe anemia, glaucoma, or recent PDE5 intake—discontinue if allergic reactions appear.\n\nDosage Guidelines\nInitiate at 30-40mg daily, titrating to 60mg once in the morning on an empty stomach for optimal absorption. Swallow whole; do not crush. A 10-12 hour nitrate-free window (nighttime) prevents tolerance.\n\nAdjust for renal/hepatic impairment; max 120mg/day. Store below 25°C. Regular ECG and BP checks ensure efficacy.\nConclusion\nCARDULES ISMN SR 60 stands as a cornerstone in angina prophylaxis, empowering CAD patients with reliable, sustained vascular relief from Steris Healthcare. Consistent use alongside diet, exercise, and smoking cessation maximizes outcomes, but cardiologist oversight remains essential for safety",
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"description": "OVOCYST M is a specialized sustained-release tablet combining Myoinositol 600mg and Metformin SR 500mg, primarily designed to address polycystic ovary syndrome (PCOS) and related metabolic issues in women. This formulation from Steris Healthcare Pvt Ltd targets insulin resistance, hormonal imbalances, and ovulatory dysfunction, making it a go-to option for restoring reproductive wellness. By improving insulin sensitivity and ovarian function, OVOCYST M supports regular cycles and fertility outcomes effectively.\n\nProduct Composition and Mechanism\nOVOCYST M features Myoinositol 600mg, a natural insulin signaling mediator that enhances cellular health and oocyte quality in PCOS patients. Paired with Metformin SR 500mg, a sustained-release biguanide that lowers hepatic glucose production and boosts peripheral insulin uptake, this duo tackles root causes like hyperinsulinemia. The SR technology ensures gradual release, minimizing digestive upset while providing prolonged metabolic support throughout the day.\n\nThis synergistic action restores ovulatory cycles by balancing hormones such as FSH and LH, reducing androgen excess common in PCOS. Women experiencing anovulation or irregular menses find OVOCYST M particularly beneficial as it promotes follicular development without aggressive interventions.\n\nKey Uses of OVOCYST M\nOVOCYST M excels in managing PCOS symptoms, including irregular menstrual cycles and infertility linked to insulin resistance. Healthcare providers often prescribe it for hyperandrogenism, where elevated male hormones cause hirsutism or acne, alongside metabolic syndrome features like obesity.\n\nSupports fertility treatments by improving egg quality and implantation rates in assisted reproduction.\nAids weight management in PCOS by curbing insulin-driven fat accumulation.\nRegulates blood sugar in prediabetic women with PCOS, preventing progression to type 2 diabetes.\nTypically taken once or twice daily with meals, the dosage aligns with physician guidance for optimal results over 4-12 weeks.\n\nMajor Benefits for PCOS and Beyond\nOne standout advantage of OVOCYST M is its ability to normalize ovulation, with studies showing improved cycle regularity in up to 70-80% of users. By enhancing insulin sensitivity, it reduces hyperinsulinemia, alleviating symptoms like fatigue and cravings that hinder daily life.\n\nPromotes modest weight loss (2-5kg over months) through better metabolic control, boosting self-esteem and mobility.\n\nEnhances fertility by maturing oocytes and lowering miscarriage risks in PCOS pregnancies.\n\nLowers androgen levels, clearing skin issues and reducing unwanted hair growth for aesthetic and emotional relief.\n\nLong-term use under supervision sustains these gains, fostering holistic health improvements like better energy and mood stability.\n\nPotential Side Effects and Precautions\nWhile generally well-tolerated, OVOCYST M may cause mild gastrointestinal effects such as nausea, flatulence, or a metallic taste from Metformin. These often subside with time or food intake, thanks to the SR formulation's gentler profile.\n\nRare but serious risks include lactic acidosis in those with kidney/liver issues, warranting avoidance in such cases. Precautions involve monitoring blood sugar, avoiding during acute illnesses, and consulting doctors if pregnant or breastfeeding.\n\nCommon: Bloating or diarrhea, manageable by starting low dose.\n\nConsult promptly for persistent vomiting or weakness.\n\nConclusion\nOVOCYST M stands as a reliable, science-backed ally for women battling PCOS, insulin resistance, and fertility hurdles through its potent Myoinositol 600mg and Metformin SR 500mg blend. Delivering tangible benefits like restored cycles, weight control, and enhanced conception chances, it empowers proactive reproductive health management. Always pair with lifestyle tweaks like balanced diet and exercise for peak efficacy, and rely on professional oversight for safe, sustained results—transforming challenges into opportunities for vitality.",
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"name": "Ursodeoxycholic Acid 600 mg",
"description": "Ursodeoxycholic Acid 600 mg is a clinically trusted and widely prescribed medication used in the management of liver and gallbladder disorders. Belonging to the class of bile acid derivatives, it plays a vital role in improving liver function and dissolving certain types of gallstones without surgery. This medicine is commonly prescribed to patients suffering from cholestatic liver diseases, such as primary biliary cholangitis (PBC), non-alcoholic fatty liver disease (NAFLD), and bile reflux gastritis.\n\nIn the Indian healthcare setting, Ursodeoxycholic Acid (also known as UDCA) has become a cornerstone therapy for liver protection. It is known not only for its effectiveness in improving bile flow but also for its anti-inflammatory, immunomodulatory, and cytoprotective properties. The 600 mg strength formulation provides an optimal dose for adult patients, ensuring consistent bile regulation and liver cell protection.\n\nProduced under stringent quality control by leading pharmaceutical companies like Steris Healthcare Pvt. Ltd., Ursodeoxycholic Acid 600 mg ensures purity, efficacy, and patient safety. This makes it a dependable choice for clinicians and patients managing chronic liver diseases in India.\n\nWhat is Ursodeoxycholic Acid?\n\nUrsodeoxycholic Acid (UDCA) is a naturally occurring bile acid that is present in small amounts in the human body. It is synthesized and used as a medication to treat liver and gallbladder conditions by altering bile composition and reducing the production of toxic bile acids.\n\nChemically, Ursodeoxycholic Acid is a hydrophilic bile acid, meaning it has a high affinity for water and helps replace harmful hydrophobic bile acids that can damage liver cells. It is known for its ability to protect hepatocytes (liver cells) from injury, enhance bile secretion, and dissolve cholesterol-based gallstones.\n\nBy reducing bile cholesterol saturation and promoting bile flow, UDCA helps maintain liver function, especially in conditions where bile flow is obstructed or impaired.\n\nMechanism of Action\n\nThe therapeutic action of Ursodeoxycholic Acid is multifaceted:\n\nBile Flow Regulation:\nUDCA improves bile secretion and reduces bile stasis (retention). This helps in clearing toxic bile acids from the liver, thereby preventing inflammation and fibrosis.\n\nCytoprotective Effect:\nIt stabilizes the hepatocyte (liver cell) membrane and reduces damage caused by bile acid-induced oxidative stress.\n\nImmunomodulatory Action:\nUrsodeoxycholic Acid reduces autoimmune destruction of bile ducts in diseases like primary biliary cholangitis by modulating immune response.\n\nCholesterol Reduction:\nUDCA decreases the cholesterol content of bile and suppresses hepatic cholesterol synthesis, leading to the gradual dissolution of cholesterol gallstones.\n\nAntifibrotic and Anti-inflammatory Role:\nBy reducing inflammation and fibrosis markers, UDCA helps slow the progression of chronic liver diseases.\n\nTherapeutic Uses of Ursodeoxycholic Acid 600 mg\n\nUrsodeoxycholic Acid 600 mg tablets are prescribed for a wide range of liver and gallbladder-related conditions. Below are the major medical indications:\n\n1. Primary Biliary Cholangitis (PBC):\n\nOne of the most common uses of UDCA is in treating primary biliary cholangitis, an autoimmune condition that causes slow, progressive destruction of bile ducts within the liver. Ursodeoxycholic Acid helps improve bile flow, reduce bilirubin levels, and delay the need for liver transplantation in many patients.\n\n2. Cholestatic Liver Diseases:\n\nIt is used to treat cholestatic conditions where bile secretion is impaired, such as:\n\nIntrahepatic cholestasis during pregnancy\n\nDrug-induced cholestasis\n\nChronic cholestatic hepatitis\n\nPost-surgical biliary obstruction\n\n3. Gallstone Dissolution (Cholesterol Gallstones):\n\nUrsodeoxycholic Acid 600 mg is effective in dissolving small, non-calcified cholesterol gallstones in patients who cannot undergo surgery. It works by reducing cholesterol saturation in bile, gradually breaking down gallstones over several months.\n\n4. Non-Alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic Steatohepatitis (NASH):\n\nIn patients with fatty liver or metabolic liver disorders, UDCA helps improve liver enzyme levels and reduces oxidative stress, supporting better liver health.\n\n5. Bile Reflux Gastritis:\n\nUDCA is used to relieve symptoms caused by bile reflux into the stomach, such as epigastric pain, bloating, and nausea.\n\n6. Cystic Fibrosis-Related Liver Disease:\n\nIt can be used to improve bile flow and prevent hepatic complications in patients with cystic fibrosis.\n\n7. Post Liver Transplantation:\n\nUDCA is sometimes used as supportive therapy to prevent graft-related cholestasis and maintain optimal liver function after transplantation.\n\nKey Benefits of Ursodeoxycholic Acid 600 mg\n1. Promotes Healthy Liver Function\n\nUrsodeoxycholic Acid supports liver detoxification and enhances bile secretion, reducing bile stasis and protecting hepatocytes from toxic damage.\n\n2. Dissolves Cholesterol Gallstones Naturally\n\nUnlike surgical interventions, UDCA provides a non-invasive way to dissolve cholesterol gallstones, especially in patients unfit for surgery.\n\n3. Protects Liver Cells from Damage\n\nUDCA stabilizes the hepatocyte membrane and reduces cell injury caused by bile acids, alcohol, or medications.\n\n4. Reduces Inflammation and Fibrosis\n\nIts anti-inflammatory and antifibrotic properties help slow down the progression of chronic liver diseases.\n\n5. Regulates Cholesterol Levels\n\nUrsodeoxycholic Acid lowers bile cholesterol concentration, which helps maintain a balanced lipid profile and prevents gallstone formation.\n\n6. Supports Recovery in Liver Disorders\n\nIn patients with hepatitis, fatty liver, or cirrhosis, UDCA helps improve liver enzyme levels (ALT, AST, ALP), signaling better liver recovery.\n\n7. Improves Digestive Function\n\nBy improving bile flow, UDCA enhances fat digestion and reduces symptoms like bloating, nausea, and postprandial discomfort.\n\n8. Safe for Long-Term Use\n\nWhen prescribed under medical supervision, Ursodeoxycholic Acid 600 mg is well-tolerated and safe for prolonged treatment of chronic liver diseases.\n\nDosage and Administration\n\nRecommended Dose: The typical adult dose of Ursodeoxycholic Acid ranges between 8–12 mg per kilogram of body weight per day, which equals about 600 mg once or twice daily depending on the patient’s condition.\n\nFormulation: Tablet form (Ursodeoxycholic Acid 600 mg)\n\nMode of Administration: Oral\n\nTiming: It should be taken with meals to enhance absorption and reduce gastrointestinal side effects.\n\nTreatment Duration:\n\nFor gallstone dissolution, therapy may last for 6 months to 2 years.\n\nFor chronic liver conditions, treatment may be long-term or lifelong under physician guidance.\n\nImportant Note:\nThe dosage should be individualized based on body weight, liver function, and medical condition. Patients must not self-medicate and should take the medicine only as prescribed by a healthcare professional.\n\nPrecautions and Warnings\n\nBefore using Ursodeoxycholic Acid 600 mg, patients should consider the following precautions:\n\nMedical Supervision Required:\nAlways use this medicine under the guidance of a doctor, particularly if you have a history of severe liver or gallbladder disease.\n\nAvoid in Certain Gallstones:\nUDCA is not effective for calcified or pigment gallstones.\n\nPregnancy and Breastfeeding:\nWhile UDCA is considered relatively safe during pregnancy, it should only be used when prescribed by a physician. Minimal amounts may pass into breast milk.\n\nMonitor Liver Function:\nRegular liver function tests (LFTs) are advised during treatment to monitor therapeutic response and liver health.\n\nDrug Interactions:\nAvoid concurrent use with:\n\nAluminum-based antacids (reduce UDCA absorption)\n\nCholestyramine or Colestipol (interfere with bile acid absorption)\n\nCiclosporin or Estrogens (may alter bile composition)\n\nAlcohol Consumption:\nAlcohol can strain the liver and reduce the effectiveness of UDCA therapy. Patients should limit or avoid alcohol during treatment.\n\nGastrointestinal Disorders:\nUse with caution in patients with peptic ulcer, severe diarrhea, or gastrointestinal inflammation.\n\nPossible Side Effects of Ursodeoxycholic Acid 600 mg\n\nUrsodeoxycholic Acid is generally well-tolerated, but some patients may experience mild to moderate side effects. These are typically temporary and improve as the body adjusts to the medication.\n\nCommon Side Effects:\n\nDiarrhea or loose stools\n\nNausea and vomiting\n\nAbdominal discomfort\n\nIndigestion or bloating\n\nHeadache\n\nDizziness\n\nLess Common Side Effects:\n\nRash or itching (urticaria)\n\nIncreased liver enzymes (temporary)\n\nBack pain or joint pain\n\nCough or upper respiratory infection symptoms\n\nRare but Serious Side Effects:\n\nSevere right upper abdominal pain (may indicate gallstone complications)\n\nJaundice or dark urine (signs of liver stress)\n\nPersistent diarrhea or dehydration\n\nAllergic reaction (swelling, rash, or shortness of breath)\n\nNote:\nIf any of these side effects persist or worsen, it is important to inform your doctor immediately. Never stop or alter the dosage without consulting your healthcare provider.\n\nSafety in Special Populations\nPregnancy:\n\nUDCA is sometimes used to treat intrahepatic cholestasis of pregnancy (ICP) under strict medical supervision. While generally safe, dosage adjustment and monitoring are essential.\n\nLactation:\n\nIt is considered safe in breastfeeding mothers as minimal quantities are excreted into breast milk.\n\nElderly Patients:\n\nNo specific dosage adjustment is needed, but liver function should be monitored regularly.\n\nChildren:\n\nUrsodeoxycholic Acid can be prescribed in pediatric doses for liver-related disorders, particularly biliary atresia, under pediatric supervision.\n\nStorage and Handling\n\nStore in a cool, dry place below 25°C.\n\nProtect from moisture and direct sunlight.\n\nKeep out of reach of children.\n\nDo not use after the expiry date printed on the pack.\n\nClinical Efficacy and Research Insights\n\nClinical studies across India and globally have confirmed the efficacy of Ursodeoxycholic Acid in managing chronic liver and biliary diseases. Long-term use of UDCA has shown:\n\nImprovement in liver enzyme profiles (AST, ALT, ALP).\n\nReduction in bilirubin levels in cholestatic conditions.\n\nDelay in disease progression in primary biliary cholangitis.\n\nReduction in gallstone size and formation rate with consistent therapy.\n\nBetter quality of life scores among patients with chronic liver conditions.\n\nIts established safety profile and biochemical benefits make Ursodeoxycholic Acid a cornerstone therapy in hepatology.\n\nLifestyle and Dietary Recommendations During Treatment\n\nTo enhance the effectiveness of UDCA therapy and support liver health, patients are advised to:\n\nMaintain a Balanced Diet:\nInclude fresh fruits, vegetables, whole grains, and lean proteins. Avoid fatty, fried, and processed foods.\n\nStay Hydrated:\nDrink sufficient water to aid digestion and toxin elimination.\n\nLimit Alcohol and Caffeine:\nBoth can strain liver metabolism and interfere with medication effectiveness.\n\nExercise Regularly:\nModerate physical activity helps improve liver function and reduce fat accumulation.\n\nAvoid Self-Medication:\nConsult your doctor before using any over-the-counter supplements or herbal products.\n\nFrequently Asked Questions (FAQs)\n\nQ1. How long should Ursodeoxycholic Acid 600 mg be taken?\nThe duration depends on your condition. For gallstone dissolution, treatment may last 6–24 months. For chronic liver diseases, long-term therapy may be recommended.\n\nQ2. Can Ursodeoxycholic Acid cure liver disease completely?\nWhile it does not cure liver disease, UDCA can slow its progression, protect liver cells, and improve biochemical and clinical outcomes.\n\nQ3. Can I take Ursodeoxycholic Acid on an empty stomach?\nIt is best taken with food to enhance absorption and minimize stomach upset.\n\nQ4. Does it interact with other medications?\nYes. Antacids, cholesterol-binding resins, and estrogens may interfere with UDCA absorption or activity. Always inform your doctor about all medications you’re taking.\n\nQ5. How long does it take to see results?\nLiver function improvement can often be observed within a few weeks, but gallstone dissolution may take several months of consistent use.\n\nConclusion\n\nUrsodeoxycholic Acid 600 mg is a trusted and clinically validated therapy for various liver and gallbladder conditions. Its unique ability to enhance bile flow, protect liver cells, and dissolve cholesterol gallstones makes it an indispensable part of hepatology treatment protocols.",
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"description": "TELAVINCE EM is primarily indicated for the management of:\n\nHypertension (High Blood Pressure): Helps in reducing elevated blood pressure effectively.\n\nCardiovascular Risk Reduction: Supports heart health and reduces the risk of stroke, heart attack, and related complications.\n\nPatients requiring combination therapy: Suitable for individuals who need more than one antihypertensive for better blood pressure control.\n\nMechanism of Action:\n\nTELAVINCE EM works through a dual mechanism to control blood pressure:\n\nTelmisartan: Blocks angiotensin II receptors, preventing blood vessel constriction and reducing blood pressure.\n\n[EM Component, e.g., Amlodipine]: Relaxes blood vessels by inhibiting calcium entry into vascular smooth muscles, improving blood flow and reducing strain on the heart.\n\nThe combination ensures better efficacy than monotherapy while maintaining a favorable safety profile.\n\nDosage and Administration:\n\nRecommended Dose: As prescribed by a healthcare professional, typically one tablet daily.\n\nRoute: Oral administration with water.\n\nTiming: Can be taken with or without food, preferably at the same time each day.\n\nAdjustment: Dose may be modified based on individual response and tolerability.\n\nImportant: Always follow your doctor’s instructions. Do not alter the dose or stop medication without medical advice.\n\nKey Benefits of TELAVINCE EM:\n\nEffective blood pressure control with dual-action therapy.\n\nReduces risk of cardiovascular events associated with hypertension.\n\nConvenient once-daily dosing improves patient compliance.\n\nWell-tolerated with a low incidence of side effects.\n\nSuitable for long-term use under medical supervision.\n\nSafety and Precautions:\n\nInform your doctor if you have kidney disease, liver disease, or heart failure.\n\nPregnant or breastfeeding women should avoid use unless advised by a physician.\n\nAvoid excessive salt substitutes containing potassium.\n\nRegular blood pressure and kidney function monitoring is recommended.\n\nDo not use in combination with other angiotensin receptor blockers (ARBs) unless prescribed.\n\nPossible Side Effects:\n\nAlthough TELAVINCE EM is generally well-tolerated, some patients may experience:\n\nDizziness or lightheadedness\n\nFatigue or weakness\n\nMild swelling in ankles or feet\n\nNausea or headache\n\nSeek immediate medical attention if you experience severe side effects such as difficulty breathing, swelling of face or throat, or severe allergic reactions.\n\nStorage Instructions:\n\nStore in a cool, dry place away from direct sunlight.\n\nKeep out of reach of children and pets.\n\nDo not use after the expiry date mentioned on the package.\n\nWhy Choose TELAVINCE EM:\n\nDeveloped by Steris Healthcare Pvt. Ltd, a trusted name in pharmaceutical excellence.\n\nEnsures quality, safety, and efficacy in every tablet.\n\nDesigned for optimal patient compliance with convenient dosing.\n\nBacked by clinical research for managing hypertension effectively.\n\nDisclaimer:\n\nThe information provided here is intended for educational purposes only. TELAVINCE EM should be used only under medical supervision. Consult your healthcare provider for personalized advice. Side effects may vary from person to person.",
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