Home> Products> severe renal impairment

{ "products": [ { "_id": "68d51d9a26579f4bc195771a", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Glimepiride IP1 mg, Voglibose IP 0.2 MG & Metformin Hydrochloride IP 500 mg ", "description": "GLIMITERIS MV1 0.2 is an advanced fixed-dose combination (FDC) medication designed for adults with Type 2 Diabetes Mellitus (T2DM) who require more than lifestyle modifications or single/dual therapy to maintain optimal blood sugar levels. This innovative formulation brings together the power of three well-established antidiabetic agents—Glimepiride (1 mg), Voglibose (0.2 mg), and Metformin Hydrochloride SR (500 mg)—to provide comprehensive glycemic control.\n\nIt is particularly effective for patients struggling with postprandial hyperglycemia, fasting glucose regulation, and HbA1c reduction, making it a preferred choice in cases of poorly controlled diabetes.\n\n \n\nMechanism of Action\nThe therapeutic benefit of GLIMITERIS MV1 0.2 comes from the unique synergy of its three components, each targeting different aspects of glucose metabolism:\n\n1. Glimepiride (1 mg) – Sulfonylurea\nStimulates insulin secretion by activating pancreatic beta cells.\n\nProvides a long-lasting effect with comparatively lower hypoglycemia risk than older sulfonylureas.\n\nHelps reduce both fasting and postprandial glucose levels.\n\n2. Voglibose (0.2 mg) – Alpha-Glucosidase Inhibitor\nDelays the breakdown and absorption of carbohydrates in the intestine.\n\nMinimizes post-meal glucose spikes (PPBG).\n\nActs locally in the gut and has minimal systemic absorption, which reduces systemic side effects.\n\n3. Metformin Hydrochloride SR (500 mg) – Biguanide\nDecreases hepatic glucose production (gluconeogenesis).\n\nImproves peripheral insulin sensitivity, enhancing glucose uptake in muscles.\n\nDoes not cause hypoglycemia on its own.\n\nThe sustained-release (SR) formulation ensures extended control and reduces gastrointestinal side effects.\n\n \n\nIndications\nGLIMITERIS MV1 0.2 is indicated for:\n\nAdults with Type 2 Diabetes Mellitus.\n\nPatients inadequately controlled with monotherapy or dual therapy.\n\nManagement of fasting and postprandial hyperglycemia.\n\nLong-term HbA1c reduction as part of a comprehensive diabetes care plan.\n\n \n\nKey Benefits\n✅ Comprehensive Blood Sugar Control – Acts on fasting, post-meal, and long-term HbA1c levels.\n✅ Postprandial Spike Management – Voglibose effectively controls carbohydrate-induced sugar surges.\n✅ Reduced Pill Burden – Combines three medicines into a single tablet.\n✅ Lower Hypoglycemia Risk – Metformin and Voglibose balance out Glimepiride’s insulin-secreting effect.\n✅ Weight Management Support – Metformin may promote modest weight loss or prevent weight gain.\n✅ Improved Tolerability – SR formulation of Metformin enhances gastrointestinal comfort.\n\n \n\nDosage and Administration\nRecommended dose: One tablet once or twice daily with meals, or as directed by the physician.\n\nAdministration tips:\n\nTake with the first bite of a main meal to maximize Voglibose’s effect.\n\nSwallow whole with water; do not crush or chew the SR tablet.\n\nDose adjustments: Based on blood sugar monitoring, clinical response, and renal/hepatic function.\n\n \n\nContraindications\nGLIMITERIS MV1 0.2 is not suitable for patients with:\n\nType 1 diabetes or diabetic ketoacidosis.\n\nSevere renal impairment (eGFR <30 mL/min/1.73 m²).\n\nHepatic dysfunction.\n\nSevere gastrointestinal diseases.\n\nHistory of lactic acidosis.\n\nHypersensitivity to Glimepiride, Voglibose, or Metformin.\n\nPregnancy and lactation (unless strictly advised by a physician).\n\n \n\nWarnings and Precautions\nHypoglycemia: Risk is higher when combined with other antidiabetics or with missed meals.\n\nLactic Acidosis: A rare but life-threatening effect of Metformin—renal function monitoring is essential.\n\nGI Side Effects: Voglibose and Metformin may cause bloating, flatulence, or diarrhea (usually temporary).\n\nVitamin B12 Monitoring: Long-term Metformin use may reduce B12 absorption.\n\nLiver and Kidney Function: Regular monitoring is recommended for safe long-term use.\n\n \n\nAdverse Effects\nCommon:\nGlimepiride: Mild hypoglycemia, dizziness, slight weight gain.\n\nVoglibose: Gas, abdominal discomfort, mild diarrhea.\n\nMetformin SR: Nausea, bloating, metallic taste, loose stools.\n\nRare but Serious:\nLactic acidosis (from Metformin).\n\nSevere hypoglycemia (especially if meals are skipped).\n\nAllergic reactions such as rash, itching, or swelling.\n\nElevated liver enzymes.\n\nSeek medical attention if symptoms such as rapid breathing, confusion, severe fatigue, or muscle pain occur.\n\n \n\nDrug Interactions\nIncreased hypoglycemia risk: With insulin, beta-blockers, and sulfonylureas.\n\nReduced Metformin efficacy: With corticosteroids, estrogens, and diuretics.\n\nLactic acidosis risk: Higher with alcohol or iodinated contrast agents. ", "price": 263.0, "discountamount": 80.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2182, "imageuri": "https://productimages.withfloats.com/actual/68d51d9cdf1a4ca2c252370a.png", "tileimageuri": "https://productimages.withfloats.com/tile/68d51d9cdf1a4ca2c252370a.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-09-25T10:46:50.098Z", "updatedon": "2025-10-02T11:20:20.402Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/glimepiride-ip1-mg-voglibose-ip-0-2-mg-metformin-hydrochloride-ip-500-mg-/2182", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "GLIMITERIS MV1 0.2", "category": "", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "68c29ba02244c906e7790e2b", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "TELAVINCE 300", "description": "TELAVINCE 300 is a high-quality antiviral medication containing Tenofovir Disoproxil Fumarate 300 mg, specifically formulated for the effective management of HIV-1 infection and chronic Hepatitis B in adults and adolescents. Manufactured under strict pharmaceutical standards, TELAVINCE 300 offers consistent, potent, and clinically proven antiviral action, helping to suppress viral replication and improve immune function.\n\nTenofovir Disoproxil Fumarate is a nucleotide reverse transcriptase inhibitor (NtRTI). It works by interfering with the enzyme reverse transcriptase, which is essential for viral replication in HIV and Hepatitis B viruses. By inhibiting this enzyme, TELAVINCE 300 reduces the amount of virus in the body, helping to prevent further immune system damage and liver complications.\n\n \nKey Indications:\n \n\nTELAVINCE 300 is indicated for:\n\nHIV-1 Infection: In combination with other antiretroviral agents for the treatment of HIV-1 in adults and adolescents (aged 12 years and older, weighing at least 35 kg).\n\nChronic Hepatitis B: For the treatment of chronic hepatitis B virus infection in adults and adolescents with compensated liver disease and evidence of active viral replication.\n\n \nMechanism of Action:\n \nTenofovir Disoproxil Fumarate is a prodrug of tenofovir, which, once absorbed and metabolized in the body, is converted into tenofovir diphosphate, the active form. Tenofovir diphosphate acts as a competitive inhibitor of reverse transcriptase, incorporating itself into the viral DNA chain and causing premature chain termination. This process disrupts the life cycle of the virus, significantly reducing its ability to multiply and spread.\n\n \nDosage and Administration:\n \n\nRecommended Dose for Adults and Adolescents (≥12 years, ≥35 kg): One tablet (300 mg) once daily, preferably with food.\n\nFor HIV Treatment: Administer in combination with other antiretroviral medications as per the treatment regimen.\n\nFor Chronic Hepatitis B: Monotherapy or as part of combination therapy, depending on patient condition and physician's assessment.\n\nDosage adjustments may be required in patients with renal impairment. Close monitoring is recommended for patients with existing kidney disease.\n\n \nKey Benefits of TELAVINCE 300:\n \n\nPotent Antiviral Action: Rapid and sustained suppression of HIV and HBV replication.\nOnce-Daily Dosing: Improves patient compliance and treatment adherence.\n\nBacked by Clinical Research: Proven efficacy in managing viral load and improving immune markers (CD4 count).\n\nTrusted Quality: Manufactured under GMP-certified facilities with stringent quality control processes.\n\nPart of First-Line Therapy: Recommended in various national and international treatment guidelines for HIV and Hepatitis B.\n\n \nSafety and Precautions:\n \n\nRenal Monitoring: Tenofovir may affect kidney function. Routine renal function tests are recommended before and during treatment.\n\nBone Mineral Density: Long-term use may reduce bone mineral density. Consider monitoring in patients at risk of osteopenia or osteoporosis.\n\nHepatic Flare: Discontinuation of therapy in hepatitis B patients may result in severe acute exacerbations. Liver function should be closely monitored post-treatment.\n\nLactic Acidosis and Hepatomegaly: Rare but serious side effects. Patients presenting symptoms such as abdominal pain, fatigue, or difficulty breathing should seek immediate medical attention.\n\n \n\nPossible Side Effects:\n \n\nMost patients tolerate TELAVINCE 300 well. However, some may experience:\n\nNausea\n\nDiarrhea\n\nHeadache\n\nFatigue\n\nRash\n\nDizziness\n\nDecreased bone mineral density\n\nRenal impairment (in rare cases)\n\nIf any side effects persist or worsen, consult a healthcare professional immediately.\n\n \nStorage Instructions:\n \n\nStore in a cool, dry place below 30°C.\n\nProtect from light and moisture.\n\nKeep out of reach of children.\n\n \n\nWhy Choose TELAVINCE 300?\n \n\nTELAVINCE 300 offers a dependable, clinically validated solution for the long-term management of HIV and Hepatitis B. With its once-daily dosing and proven effectiveness, TELAVINCE 300 is an ideal choice for patients and healthcare providers looking for quality, safety, and therapeutic reliability. It is manufactured by a trusted name in healthcare, ensuring every tablet meets global pharmaceutical standards.\n\n \nDisclaimer:\n \n\nThis product description is for informational purposes only and is not a substitute for professional medical advice. Always consult your doctor or healthcare provider before starting any medication.", "price": 1480.0, "discountamount": 444.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2179, "imageuri": "https://productimages.withfloats.com/actual/68c29ba3794abb27ab248d73.png", "tileimageuri": "https://productimages.withfloats.com/tile/68c29ba3794abb27ab248d73.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-09-11T09:51:28.508Z", "updatedon": "2025-09-11T09:51:28.508Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/telavince-300/2179", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Tenofovir Disoproxil Fumarate Tablets ip 300 mg", "category": "GENERAL RANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6891b0287b16001ae8bc9da2", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "CITICOTIME PM", "description": "CITICOTIME PM is a specialized formulation combining Citicoline 500mg and Piracetam 800mg in tablet form, designed to enhance brain health and cognitive functions. This combination harnesses the synergistic effects of two well-researched nootropic agents—citicoline and piracetam tablets—widely used in neurological therapies. Primarily, this medicine supports nerve cell nourishment, protects neurons from damage, and aids in improving memory, focus, and recovery in brain-related conditions such as stroke. Its unique formulation offers neuroprotection and cognitive enhancement, making it an important therapeutic option in treating stroke and other cognitive impairments.\n\nWhat is CITICOTIME PM?\nCITICOTIME PM contains a combination of two active ingredients: Citicoline 500mg, a neuroprotective compound that promotes brain cell repair and function, and Piracetam 800mg, which enhances neuronal communication and cognitive processes. Together, they work to support brain metabolism, improve blood flow, and strengthen cognitive resilience. This formulation is often prescribed to patients recovering from neurological injuries or those experiencing cognitive decline.\n\nUses of Citicoline and Piracetam Tablets\n\nTreatment and recovery support in stroke patients to restore brain function\n\nImprovement of memory, learning ability, and cognitive performance\n\nManagement of neurological disorders such as dementia and Alzheimer's disease\n\nNeuroprotection against brain cell damage caused by trauma or ischemia\n\nEnhancement of mental alertness and reduction of cognitive fatigue\n\nSupport in conditions involving cognitive impairment due to aging or injury\n\nCiticoline + Piracetam is used in the treatment of stroke. Citicoline + Piracetam is a combination of two medicines: Citicoline and Piracetam. Citicoline is a nerve protecting medicine. It works on the brain by nourishing the nerve cells, protects them from damage and improves their survival.\n\nCiticoline and Piracetam Tablets Dosage\nThe recommended dosage depends on the patient's condition, age, and response to therapy. Typically, CITICOTIME PM is taken once or twice daily as prescribed by a healthcare professional. Each tablet delivers Citicoline 500mg and Piracetam 800mg, providing an effective dose for neuroprotection and cognitive support. It should be swallowed whole with water, preferably after meals to reduce gastrointestinal discomfort. Dosage adjustments may be necessary in patients with kidney impairment or other comorbidities. It is critical to follow a doctor's prescribed dosage and not to self-medicate.\n\nSide Effects of Citicoline and Piracetam Tablets\nWhile generally well tolerated, some individuals may experience side effects, which are usually mild and temporary, including:\n\nHeadache\n\nNausea and stomach discomfort\n\nInsomnia or trouble sleeping\n\nNervousness or agitation\n\nDizziness and vertigo\n\nWeight gain in some cases\n\nRare allergic reactions such as skin rash or swelling\n\nChanges in blood pressure or heart rate (typically uncommon)\n\nIf severe side effects or allergic reactions occur, immediate medical attention is advised.\n\nPrecautions Before Using CITICOTIME PM\n\nConsult a doctor before use if you have a history of brain hemorrhage, bleeding disorders, or gastrointestinal ulcers.\n\nUse caution in elderly patients and those with renal or hepatic impairment.\n\nAvoid driving or operating heavy machinery until you know how the medicine affects you.\n\nDo not consume alcohol while taking this medication, as it may increase side effects like drowsiness or nervousness.\n\nInform your healthcare provider if you are pregnant, trying to conceive, or breastfeeding, as safety in these conditions is not fully established.\n\nDo not abruptly stop the medication without medical advice to avoid withdrawal symptoms such as muscle twitching.\n\nDrug Interactions: What Drugs Interact with CITICOTIME PM?\n\nAnticoagulants or blood thinners may increase the risk of bleeding.\n\nOther central nervous system (CNS) stimulants or depressants can enhance side effects like dizziness or drowsiness.\n\nMedications processed by kidneys require careful monitoring as both citicoline and piracetam are primarily excreted renally.\n\nAlcohol consumption can exacerbate side effects, especially sedation and nervousness.\n\nAlways inform your doctor about all medications and supplements you are taking to avoid harmful interactions.\n\nCITICOTIME PM, with citicoline 500mg and piracetam 800mg, is a reliable choice for managing stroke recovery and cognitive disorders by protecting and nourishing nerve cells, improving brain function, and supporting neuronal survival. Proper medical supervision is essential to maximize benefits and minimize risks associated with citicoline and piracetam tablets uses and dosage.", "price": 529.0, "discountamount": 159.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2155, "imageuri": "https://productimages.withfloats.com/actual/6891b02f5058847bfcd48899.png", "tileimageuri": "https://productimages.withfloats.com/tile/6891b02f5058847bfcd48899.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-08-05T07:18:00.92Z", "updatedon": "2025-08-05T07:18:00.92Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/citicotime-pm/2155", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "citicoline and piracetam tablets", "category": "NEUROLOGY RANGE", "tags": [ "citicoline and piracetam tablets" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "668e8611b9f7300708fe1240", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "TRIOGLIMITERIS 1/0.2 ", "description": "TRIOGLIMITERIS 1/0.2 \nVoglibose 0.2 mg, Glimepiride 1 mg & Metformin Hydrochloride 500 mg\nIntroduction\n\nTRIOGLIMITERIS 1/0.2 is a combination medication containing Voglibose, Glimepiride, and Metformin Hydrochloride. It is primarily used in the management of type 2 diabetes mellitus to improve glycemic control through different mechanisms of action targeting glucose metabolism.\n\nComposition\n\nVoglibose (0.2 mg): An alpha-glucosidase inhibitor that delays the digestion of carbohydrates in the intestine, thereby reducing postprandial blood glucose levels.\nGlimepiride (1 mg): A sulfonylurea derivative that stimulates insulin release from pancreatic beta cells, enhancing glucose uptake in peripheral tissues.\nMetformin Hydrochloride (500 mg): A biguanide that decreases hepatic glucose production, improves insulin sensitivity in peripheral tissues, and reduces intestinal glucose absorption.\nMechanism of Action\n\nTRIOGLIMITERIS 1/0.2 combines the actions of its components to achieve optimal glycemic control:\n\nVoglibose: Inhibits alpha-glucosidase enzymes in the intestine, delaying carbohydrate digestion and reducing the absorption of glucose after meals.\nGlimepiride: Stimulates insulin secretion from pancreatic beta cells in a glucose-dependent manner, thereby lowering blood glucose levels.\nMetformin Hydrochloride: Decreases hepatic glucose production through suppression of gluconeogenesis and enhances peripheral glucose uptake and utilization by improving insulin sensitivity.\nIndications\n\nTRIOGLIMITERIS 1/0.2 is indicated for:\n\nType 2 Diabetes Mellitus: Used to improve glycemic control in adults when diet, exercise, and monotherapy with metformin or sulfonylureas alone are not sufficient.\nDosage and Administration\n\nThe typical dosage of TRIOGLIMITERIS 1/0.2 is one tablet taken orally with meals, usually once or twice daily.\nDosage adjustments may be required based on individual patient response, blood glucose levels, and renal function.\nIt is essential to adhere to the prescribed dosage regimen to achieve optimal therapeutic outcomes.\nSide Effects\n\nCommon side effects of TRIOGLIMITERIS 1/0.2 may include:\n\nHypoglycemia (especially when used in combination with insulin or other antidiabetic medications)\nGastrointestinal disturbances (such as nausea, vomiting, diarrhea, or abdominal discomfort)\nWeight gain (mainly associated with sulfonylureas)\nMore severe side effects can include:\n\nAllergic reactions (rash, itching, swelling)\nLactic acidosis (rare but serious adverse effect associated with metformin use)\nHepatic dysfunction (monitor liver function tests periodically)\nPrecautions\n\nUse with caution in patients with renal impairment, hepatic dysfunction, or other significant medical conditions that may affect drug metabolism or excretion.\nRegular monitoring of blood glucose levels, renal function, and liver function is recommended during treatment with TRIOGLIMITERIS 1/0.2.\nAvoid use in patients with type 1 diabetes mellitus or diabetic ketoacidosis.\nDrug Interactions\n\nTRIOGLIMITERIS 1/0.2 may interact with other medications affecting blood glucose levels, such as insulin, other oral antidiabetic agents, or drugs that affect renal function or hepatic metabolism. Close monitoring and dose adjustments may be necessary.\nConclusion\n\nTRIOGLIMITERIS 1/0.2 provides a comprehensive approach to managing type 2 diabetes mellitus by combining Voglibose, Glimepiride, and Metformin Hydrochloride. This combination targets different aspects of glucose metabolism, enhancing insulin secretion, reducing hepatic glucose production, and delaying carbohydrate absorption in the intestine. Proper dosage, administration, and monitoring for side effects are essential to achieve and maintain optimal glycemic control in diabetic patients using TRIOGLIMITERIS 1/0.2. Consultation with a healthcare provider is recommended for personalized treatment plans and management of diabetes with this medication.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order NOW\n", "price": 195.0, "discountamount": 58.5, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "500 mg", "0.2 mg", "one tablet", "Weight gain", "Glimepiride 1", "metformin use", "Proper dosage", "Glimepiride (1", "dosage regimen", "typical dosage", "renal function", "insulin release", "drug metabolism", "Lactic acidosis", "Close monitoring", "dose adjustments", "renal impairment", "diabetic patients", "insulin secretion", "different aspects", "Drug Interactions", "other medications", "Regular monitoring", "Dosage adjustments", "Allergic reactions", "peripheral tissues", "hepatic metabolism", "glucose metabolism", "insulin sensitivity", "healthcare provider", "Hepatic dysfunction", "Common side effects", "abdominal discomfort", "different mechanisms", "liver function tests", "diabetic ketoacidosis", "pancreatic beta cells", "combination medication", "carbohydrate digestion", "comprehensive approach", "serious adverse effect", "Metformin Hydrochloride", "carbohydrate absorption", "sulfonylurea derivative", "glucose-dependent manner", "optimal glycemic control", "type 1 diabetes mellitus", "type 2 diabetes mellitus", "More severe side effects", "alpha-glucosidase enzymes", "peripheral glucose uptake", "hepatic glucose production", "alpha-glucosidase inhibitor", "individual patient response", "personalized treatment plans", "optimal therapeutic outcomes", "Gastrointestinal disturbances", "intestinal glucose absorption", "other antidiabetic medications", "other oral antidiabetic agents", "postprandial blood glucose levels", "other significant medical conditions" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1939, "imageuri": "https://productimages.withfloats.com/actual/668e86143a68154e11e7d822.jpeg", "tileimageuri": "https://productimages.withfloats.com/tile/668e86143a68154e11e7d822.jpeg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-07-10T13:01:05.875Z", "updatedon": "2024-07-10T13:01:05.875Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/trioglimiteris-1-0-2-/1939", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "TRIOGLIMITERIS 1/0.2 ", "category": "DIABETIC RANGE", "tags": [ "glimepiride 1mg+metformin 500mg+voglibose 0.2 mg", "Glimepiride 2mg Metformin 500mg Voglibose 0.2 mg b", "glimepiride 2mg+metformin 500mg+voglibose 0.2 mg", "voglibose glimepiride & metformin hydrochloride (s", "voglibose glimepiride + metformin hydrochloride us", "glimepiride 1mg+metformin 500mg+voglibose 0.3 mg", "glimepiride 2mg+metformin 500mg+voglibose 0.2 mg g", "" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "668e7ff07e47881008f6860e", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "TRIMETAZ CR 80 ", "description": "TRIMETAZ CR 80 \nTrimetazidine (80mg)\nIntroduction\nTRIMETAZ CR 80 is a medication containing Trimetazidine hydrochloride, formulated to treat angina pectoris and certain other cardiovascular conditions. It is known for its metabolic effects on the heart muscle, improving myocardial efficiency and reducing symptoms associated with ischemic heart disease.\n\nComposition\n\nTrimetazidine (80mg): The active ingredient, Trimetazidine, acts as a cellular metabolic agent that enhances myocardial glucose utilization and improves energy production in the heart muscle.\nMechanism of Action\nTrimetazidine exerts its therapeutic effects through several mechanisms:\n\nMetabolic Regulation: Shifts myocardial energy substrate utilization from fatty acids toward glucose oxidation, which is more efficient and requires less oxygen.\nAnti-ischemic Effect: Protects the heart against ischemic damage by preserving cellular energy metabolism and reducing oxidative stress.\nImprovement in Symptomatology: Reduces angina symptoms such as chest pain, shortness of breath, and exercise intolerance by enhancing myocardial function.\nIndications\nTRIMETAZ CR 80 is indicated for:\n\nChronic Stable Angina Pectoris: Used as adjunctive therapy in patients who are inadequately controlled with other anti-anginal medications.\nIschemic Heart Disease: Helps improve myocardial function and reduce symptoms associated with coronary artery disease.\nDosage and Administration\n\nThe usual dosage of TRIMETAZ CR 80 is one tablet (80mg) taken orally twice daily, preferably with meals.\nThe extended-release formulation ensures sustained therapeutic levels of Trimetazidine throughout the day.\nDosage adjustments may be necessary based on individual patient response and tolerance.\nSide Effects\nCommon side effects may include:\n\nHeadache\nDizziness\nNausea\nGastrointestinal disturbances (such as abdominal pain or diarrhea)\nSevere side effects are rare but may include:\n\nAllergic reactions (rash, itching, swelling)\nExtrapyramidal symptoms (involuntary movements)\nHepatic dysfunction (monitor liver function tests periodically)\nPrecautions\n\nUse with caution in patients with severe renal impairment or hepatic dysfunction, as Trimetazidine metabolism may be altered.\nMonitor patients for signs of extrapyramidal symptoms, especially in patients with Parkinson's disease or other movement disorders.\nAvoid abrupt discontinuation of Trimetazidine, as it may worsen angina symptoms.\nDrug Interactions\n\nTrimetazidine may interact with other medications that affect myocardial metabolism or cardiac function, including beta-blockers and calcium channel blockers. Close monitoring is recommended when used concomitantly.\nConclusion\nTRIMETAZ CR 80 is a valuable therapeutic option for managing chronic stable angina pectoris and ischemic heart disease by improving myocardial efficiency and reducing symptoms associated with cardiac ischemia. Its mechanism of action, focusing on metabolic modulation and anti-ischemic effects, makes it an effective adjunctive therapy in patients with inadequate symptom control on standard anti-anginal medications. Proper dosage, administration, and monitoring for side effects are essential to ensure safe and effective use of TRIMETAZ CR 80 in cardiovascular patients. Consultation with a healthcare provider is recommended for personalized treatment plans and management of cardiac conditions with TRIMETAZ CR 80.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order NOW\n\n", "price": 435.0, "discountamount": 130.5, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "one tablet", "chest pain", "less oxygen", "fatty acids", "TRIMETAZ CR", "usual dosage", "heart muscle", "Proper dosage", "effective use", "abdominal pain", "angina symptoms", "ischemic damage", "Close monitoring", "cardiac ischemia", "oxidative stress", "cardiac function", "Drug Interactions", "active ingredient", "glucose oxidation", "metabolic effects", "energy production", "other medications", "Dosage adjustments", "Allergic reactions", "adjunctive therapy", "several mechanisms", "cardiac conditions", "healthcare provider", "Hepatic dysfunction", "myocardial function", "therapeutic effects", "Severe side effects", "Common side effects", "metabolic modulation", "Metabolic Regulation", "liver function tests", "involuntary movements", "anti-ischemic effects", "myocardial efficiency", "myocardial metabolism", "abrupt discontinuation", "ischemic heart disease", "Extrapyramidal symptoms", "cardiovascular patients", "coronary artery disease", "severe renal impairment", "Trimetazidine metabolism", "cellular metabolic agent", "other movement disorders", "calcium channel blockers", "cellular energy metabolism", "inadequate symptom control", "Trimetazidine hydrochloride", "valuable therapeutic option", "individual patient response", "extended-release formulation", "sustained therapeutic levels", "personalized treatment plans", "Gastrointestinal disturbances", "other anti-anginal medications", "myocardial glucose utilization", "Chronic Stable Angina Pectoris", "other cardiovascular conditions", "standard anti-anginal medications", "myocardial energy substrate utilization" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1938, "imageuri": "https://productimages.withfloats.com/actual/668e7ff3f07c99c3af8e8504.jpeg", "tileimageuri": "https://productimages.withfloats.com/tile/668e7ff3f07c99c3af8e8504.jpeg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-07-10T12:34:56.538Z", "updatedon": "2024-07-10T12:34:56.538Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/trimetaz-cr-80-/1938", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "TRIMETAZ CR 80 ", "category": "CARDIOLOGYRANGE", "tags": [ "Trimetazidine 80mg price", "Trimetazidine 35 mg uses", "Trimetazidine 80 mg brand name", "When to stop taking trimetazidine", "Trimetazidine hydrochloride extended release CAPSU", "Trimetazidine mechanism of action", "Trimetazidine 35 mg brand name", "" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "668e745ca846511e502f9489", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Fabrical D3 6L ", "description": "Fabrical D3 6L \nCholecalciferol Vitamin D3 (600,000IU) Injection\nIntroduction\nFabrical D3 6L is a potent vitamin D3 (Cholecalciferol) injection, providing 600,000 IU per dose. This high-dose formulation is designed to address severe vitamin D deficiency and support overall bone health. It is particularly useful for individuals who cannot achieve adequate vitamin D levels through oral supplements or dietary intake.\n\nComposition\n\nCholecalciferol (Vitamin D3) 600,000 IU: A fat-soluble vitamin essential for the absorption of calcium and phosphorus in the body, playing a crucial role in maintaining bone health and calcium homeostasis.\nMechanism of Action\nCholecalciferol (Vitamin D3) undergoes hydroxylation in the liver to form 25-hydroxyvitamin D, which is then converted in the kidneys to its active form, calcitriol (1,25-dihydroxyvitamin D). Calcitriol enhances the intestinal absorption of calcium and phosphorus, supports bone mineralization, and modulates immune function.\n\nIndications\nFabrical D3 6L is indicated for:\n\nSevere Vitamin D Deficiency: To rapidly correct low levels of vitamin D.\nOsteoporosis: To support bone health and prevent fractures.\nHypocalcemia: To assist in the treatment of low calcium levels due to hypoparathyroidism or other conditions.\nRickets and Osteomalacia: To treat and prevent bone disorders caused by vitamin D deficiency.\nMalabsorption Syndromes: In conditions like Crohn’s disease, celiac disease, and bariatric surgery where vitamin D absorption is impaired.\nDosage and Administration\n\nAdult Dosage: Typically, a single dose of 600,000 IU is administered intramuscularly. The frequency of administration depends on the severity of deficiency and the patient's response to treatment.\nAdministration: The injection should be administered by a healthcare professional. It is important to monitor serum calcium and vitamin D levels during treatment to avoid hypercalcemia and vitamin D toxicity.\nSide Effects\nCommon side effects may include:\n\nPain at the injection site\nMild gastrointestinal disturbances (nausea, vomiting)\nFatigue\nHeadache\nMore severe side effects can include:\n\nHypercalcemia (high calcium levels), which may present with symptoms like weakness, confusion, increased thirst and urination, and abdominal pain.\nHypervitaminosis D, resulting from excessive vitamin D intake.\nPrecautions\n\nHypercalcemia: Patients should be monitored for signs of elevated calcium levels.\nKidney Function: Use with caution in patients with renal impairment as vitamin D metabolism and excretion may be affected.\nPregnancy and Lactation: High doses of vitamin D should be used under medical supervision during pregnancy and lactation.\nDrug Interactions\n\nThiazide Diuretics: May increase the risk of hypercalcemia when used with vitamin D.\nAntiepileptic Drugs: Some antiepileptics may decrease vitamin D levels.\nGlucocorticoids: May reduce the effectiveness of vitamin D by impairing calcium absorption.\nConclusion\nFabrical D3 6L, with its high-dose Cholecalciferol (600,000 IU), provides an effective treatment for severe vitamin D deficiency and related conditions. Its ability to rapidly restore adequate vitamin D levels makes it an essential therapeutic option for individuals with significant deficiencies or those who have difficulty absorbing vitamin D. As with any high-dose supplementation, it is critical to use this medication under the guidance of a healthcare professional to ensure safety and efficacy, with regular monitoring to prevent potential side effects such as hypercalcemia and vitamin D toxicity.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order NOW\n", "price": 75.0, "discountamount": 22.5, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "600,000 IU", "High doses", "low levels", "vitamin D.", "single dose", "active form", "Adult Dosage", "crucial role", "serum calcium", "injection site", "abdominal pain", "celiac disease", "bone disorders", "dietary intake", "Fabrical D3 6L", "Kidney Function", "immune function", "other conditions", "renal impairment", "oral supplements", "Drug Interactions", "bariatric surgery", "potent vitamin D3", "related conditions", "regular monitoring", "therapeutic option", "Thiazide Diuretics", "calcium absorption", "Hypervitaminosis D", "low calcium levels", "vitamin D toxicity", "effective treatment", "Antiepileptic Drugs", "medical supervision", "calcium homeostasis", "bone mineralization", "25-hydroxyvitamin D", "fat-soluble vitamin", "overall bone health", "high calcium levels", "Common side effects", "vitamin D absorption", "vitamin D metabolism", "intestinal absorption", "high-dose formulation", "25-dihydroxyvitamin D", "potential side effects", "healthcare professional", "Malabsorption Syndromes", "elevated calcium levels", "significant deficiencies", "More severe side effects", "high-dose Cholecalciferol", "high-dose supplementation", "adequate vitamin D levels", "Cholecalciferol Vitamin D3", "excessive vitamin D intake", "severe vitamin D deficiency", "Mild gastrointestinal disturbances" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1934, "imageuri": "https://productimages.withfloats.com/actual/668e74610637666af0103bb2.jpeg", "tileimageuri": "https://productimages.withfloats.com/tile/668e74610637666af0103bb2.jpeg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-07-10T11:45:32.964Z", "updatedon": "2024-07-10T11:45:32.964Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/fabrical-d3-6l-/1934", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Fabrical D3 6L ", "category": "GENERAL RANGE", "tags": [ "Vitamin D 600 000 IU injection dosage", "Vitamin D Injection 600 000 price in India", "Vitamin D3 injection dosage for adults", "Vitamin D Injection 600 000 dosage price", "Vitamin D Injection 600 000 brand name", "Vitamin D injection 600 000 benefits" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "668e6a917a3a9f14c496085b", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "FLOCLOVIR 250 ", "description": "FLOCLOVIR 250 \nFamciclovir (250mg)\nIntroduction\nFLOCLOVIR 250 is an antiviral medication containing Famciclovir (250mg), primarily used to treat infections caused by herpes viruses, including herpes zoster (shingles), genital herpes, and cold sores. Famciclovir is a prodrug that is converted into penciclovir in the body, which then inhibits viral DNA replication, reducing the severity and duration of outbreaks.\n\nComposition\n\nFamciclovir (250mg): An antiviral agent that is effective against herpes simplex virus (HSV) types 1 and 2 and varicella-zoster virus (VZV).\nMechanism of Action\nFamciclovir is converted to penciclovir in the body. Penciclovir works by inhibiting the viral DNA polymerase enzyme, which is necessary for viral DNA synthesis and replication. By blocking this enzyme, penciclovir prevents the virus from multiplying, thereby controlling the infection and reducing symptoms.\n\nIndications\nFLOCLOVIR 250 is indicated for the treatment of:\n\nHerpes Zoster (Shingles): To reduce pain and accelerate healing of shingles rashes.\nGenital Herpes: For the treatment of initial and recurrent episodes of genital herpes, as well as for suppressive therapy to reduce the frequency of outbreaks.\nCold Sores (Herpes Labialis): To reduce the severity and duration of cold sores.\nDosage and Administration\n\nHerpes Zoster: The typical dosage is 500mg every 8 hours for 7 days.\nGenital Herpes (Initial Episode): 250mg three times daily for 5-10 days.\nGenital Herpes (Recurrent Episodes): 125mg twice daily for 5 days.\nSuppressive Therapy for Genital Herpes: 250mg twice daily.\nCold Sores: 1500mg as a single dose at the first sign of symptoms.\nDosage adjustments may be necessary for patients with renal impairment. It is crucial to start treatment at the first sign of an outbreak for maximum effectiveness.\nSide Effects\nCommon side effects may include:\n\nHeadache\nNausea\nDiarrhea\nFatigue\nAbdominal pain\nLess common but more severe side effects may include:\n\nAcute renal failure (particularly in patients with pre-existing kidney disease)\nAllergic reactions (rash, itching, swelling, severe dizziness, trouble breathing)\nPrecautions\n\nAllergy: Patients with a known allergy to Famciclovir, penciclovir, or any other components should avoid using this medication.\nRenal Impairment: Dosage adjustments are necessary for patients with kidney problems.\nPregnancy and Lactation: The safety of Famciclovir in pregnant or breastfeeding women has not been fully established. It should only be used if the potential benefits outweigh the risks.\nDrug Interactions\n\nProbenecid: May increase blood levels of Famciclovir, leading to increased risk of side effects.\nOther Antivirals: Combining with other antiviral drugs may enhance therapeutic effects but also increase the risk of side effects.\nConclusion\nFLOCLOVIR 250, with its active ingredient Famciclovir, provides an effective treatment option for managing herpes virus infections. By inhibiting viral replication, it helps reduce the severity and duration of outbreaks, offering relief to patients suffering from herpes zoster, genital herpes, and cold sores. As with any medication, it is essential to use FLOCLOVIR 250 as prescribed by a healthcare professional and to consult a doctor for any concerns or potential drug interactions. Proper use ensures optimal outcomes and minimizes the risk of side effects.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order NOW\n", "price": 312.0, "discountamount": 93.6, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "5 days", "7 days", "5-10 days", "Proper use", "first sign", "cold sores", "single dose", "Less common", "blood levels", "herpes zoster", "Abdominal pain", "typical dosage", "genital herpes", "herpes viruses", "shingles rashes", "Initial Episode", "Herpes Labialis", "antiviral agent", "kidney problems", "optimal outcomes", "Diarrhea Fatigue", "Other Antivirals", "other components", "renal impairment", "severe dizziness", "active ingredient", "viral replication", "Dosage adjustments", "Allergic reactions", "recurrent episodes", "potential benefits", "breastfeeding women", "suppressive therapy", "therapeutic effects", "severe side effects", "Common side effects", "Acute renal failure", "viral DNA synthesis", "antiviral medication", "herpes simplex virus", "maximum effectiveness", "other antiviral drugs", "viral DNA replication", "varicella-zoster virus", "healthcare professional", "herpes virus infections", "existing kidney disease", "effective treatment option", "potential drug interactions", "viral DNA polymerase enzyme" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1930, "imageuri": "https://productimages.withfloats.com/actual/668e6a94f07c99c3af8e5671.jpeg", "tileimageuri": "https://productimages.withfloats.com/tile/668e6a94f07c99c3af8e5671.jpeg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-07-10T11:03:45.437Z", "updatedon": "2024-07-10T11:03:45.437Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/floclovir-250-/1930", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "FLOCLOVIR 250 ", "category": "GENERAL RANGE", "tags": [ "Famciclovir 250mg dosage", "What is famciclovir 500 mg used for", "Famciclovir 250 mg price", "Famciclovir 500 mg dosage", "Is famciclovir an antibiotic", "Famciclovir side effects" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6666d38433ebd40c046c974f", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "MIRAGRON ER 50", "description": "MIRAGRON ER 50\nMirabegron (50mg)\nMirabegron ER 50 (Mirabegron 50mg) is a medication used to treat overactive bladder (OAB) symptoms like frequent urination, urgency, and incontinence. It belongs to a class of drugs called beta-3 adrenergic agonists, which work by relaxing the bladder muscles, reducing urinary frequency and urgency.\n\nDrug Class: Beta-3 Adrenergic Agonist\nIndications: Overactive Bladder (OAB)\nActive Ingredient: Mirabegron 50mg\nDosage Form: Extended-Release Tablet (ER)\nMechanism of Action: Stimulates beta-3 adrenergic receptors in the bladder, relaxing detrusor smooth muscle, and increasing bladder capacity.\nAdministration: Take orally, usually once daily with or without food.\nEffectiveness: Improves OAB symptoms, reducing urinary frequency and urgency.\nSide Effects: May include headache, hypertension, urinary tract infection, and constipation.\nContraindications: Hypersensitivity to mirabegron, severe uncontrolled hypertension, severe hepatic impairment.\nPrecautions: Monitor blood pressure during treatment, caution in patients with severe renal impairment.\nInteractions: May interact with CYP3A4 inhibitors/inducers, antimuscarinic agents, and digoxin.\nPregnancy/Breastfeeding: Use during pregnancy only if benefits outweigh risks, not recommended during breastfeeding.\nStorage: Store at room temperature away from moisture and heat.\nMirabegron ER 50 provides effective relief for OAB symptoms with a convenient once-daily dosing regimen. However, it's important to follow your healthcare provider's instructions and report any adverse effects promptly. For further information:\nEmail: info@sterispharma.com / contact@sterispharma.com\nCall/WhatsApp: 7877551268, 7849827488\nORDER Now: \nhttps://www.sterisonline.com/product/miragron-er-50-133492\n\n\n\n\n\n\n", "price": 329.0, "discountamount": 99.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "food", "heat", "drugs", "risks", "ORDER", "Email", "Action", "urgency", "Storage", "digoxin", "WhatsApp", "moisture", "headache", "benefits", "agonists", "patients", "pregnancy", "treatment", "Mechanism", "medication", "Drug Class", "Precautions", "MIRAGRON ER", "information", "instructions", "incontinence", "sterispharma", "constipation", "sterisonline", "Side Effects", "OAB symptoms", "Mirabegron ER", "OAB) symptoms", "Breastfeeding", "Effectiveness", "blood pressure", "Administration", "bladder muscles", "convenient once", "adverse effects", "room temperature", "effective relief", "Hypersensitivity", "bladder capacity", "Contraindications", "Active Ingredient", "urinary frequency", "frequent urination", "overactive bladder", "healthcare provider", "daily dosing regimen", "antimuscarinic agents", "detrusor smooth muscle", "severe renal impairment", "Extended-Release Tablet", "urinary tract infection", "severe hepatic impairment", "CYP3A4 inhibitors/inducers", "beta-3 adrenergic receptors", "Mirabegron 50mg Dosage Form", "severe uncontrolled hypertension", "Beta-3 Adrenergic Agonist Indications" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1666, "imageuri": "https://productimages.withfloats.com/actual/6666d387897f51544741f356.png", "tileimageuri": "https://productimages.withfloats.com/tile/6666d387897f51544741f356.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-10T10:20:52.551Z", "updatedon": "2024-06-29T10:24:07.117Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/miragron-er-50/1666", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MIRAGRON ER 50", "category": "UROLOGYRANGE", "tags": [ "MIRAGRON ER 50 mg", "Mirabegron 50mg", "", "mirabegron 50 mg uses", "", "mirabegron side effects", "", "mirabegron 50 mg price", "", "mirabegron dose", "mirabegron 50 mg and solifenacin" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6891f29bfb7044dfb2d43adf", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "MAGRAL 160", "description": "MAGRAL 160 is a pharmaceutical medication containing megestrol acetate 160 mg, a synthetic progestin known for its potent antineoplastic and appetite-stimulating properties. This drug is primarily prescribed to manage significant health challenges such as unexplained weight loss, anorexia, and cachexia, especially in patients suffering from chronic conditions like cancer or AIDS. Additionally, megestrol acetate functions as a hormone therapy agent employed in the treatment of certain hormone-sensitive malignancies. Its dual action both supports tumor management and improves patients' nutritional status by stimulating appetite and promoting weight gain, thereby enhancing overall quality of life. The drug is regarded as a crucial option in oncology and palliative care for managing complex conditions related to hormone-dependent cancers and severe wasting syndromes.\n\nWhat is MAGRAL 160?\nMAGRAL 160 is an oral medication formulated with megestrol acetate 160 mg, a synthetic progestin hormone derivative. It works primarily by modulating hormone receptors and altering hormone levels that influence the growth of hormone-responsive tumors such as breast and endometrial cancers. Apart from its antineoplastic action, it stimulates appetite by acting on the hypothalamic centers responsible for hunger, helping patients suffering from severe weight loss regain a healthy appetite and weight.\n\nUses of MAGRAL 160\n\nTo treat hormone-dependent cancers, specifically advanced breast cancer and endometrial cancer.\n\nTo stimulate appetite and promote weight gain in patients experiencing anorexia, cachexia, or unexplained severe weight loss related to chronic illnesses like cancer or AIDS.\n\nTo manage wasting syndromes that lead to malnutrition and significant weight loss.\n\nTo serve as an antineoplastic agent in hormone-sensitive malignancies.\n\nIn short, MAGRAL 160 is primarily used to treat anorexia and cachexia or serious unexplained weight loss and is also used as an antineoplastic agent to treat certain types of malignancy.\n\nSide Effects of MAGRAL 160\n\nWeight gain (often desirable but can be excessive)\n\nFluid retention and edema (swelling)\n\nNausea and vomiting\n\nDiarrhea or constipation\n\nVaginal bleeding or spotting in women\n\nFatigue, weakness, and insomnia\n\nHeadache and dizziness\n\nIncreased risk of blood clots (deep vein thrombosis or pulmonary embolism)\n\nHormonal imbalances, such as decreased sex hormone levels, which can lead to sexual dysfunction or bone density loss\n\nAllergic reactions including rash or itching\n\nPatients should report severe or unusual symptoms, especially signs of blood clots such as limb swelling, chest pain, or sudden shortness of breath, immediately to their healthcare provider.\n\nPrecautions before Using MAGRAL 160\n\nInform your doctor if you are pregnant, breastfeeding, or planning to conceive as MAGRAL 160 is contraindicated in pregnancy.\n\nDisclose any history of blood clots, cardiovascular diseases, liver or kidney impairment.\n\nPatients with diabetes should monitor blood sugar closely as megestrol acetate may cause hyperglycemia.\n\nAvoid sudden discontinuation without medical advice to prevent potential hormonal withdrawal effects.\n\nRegular monitoring is required, including hormone levels and blood tests, to assess efficacy and safety during treatment.\n\nUse cautiously in patients at risk for deep vein thrombosis or pulmonary embolism due to increased clotting risks.\n\nDrug Interactions: What Drugs Interact with MAGRAL 160?\n\nCYP3A4 enzyme inducers (e.g., rifampin, phenytoin) may reduce the effectiveness of megestrol acetate by increasing its metabolism.\n\nConcurrent use with blood thinners (anticoagulants) requires careful monitoring as MAGRAL 160 might influence clotting parameters.\n\nCombining with drugs that affect hormonal pathways, such as other hormonal therapies or corticosteroids, may alter treatment outcomes.\n\nInteractions with diabetes medications might necessitate dose adjustment due to potential effects on blood sugar control.\n\nCareful medical supervision is necessary when used with immunosuppressants or other chemotherapy agents to avoid additive side effects or altered drug levels.\n\nConclusion\nMAGRAL 160, containing megestrol acetate 160 mg, is a clinically validated medication widely used to manage complex conditions such as hormone-dependent cancers as well as severe weight loss due to anorexia and cachexia. Its unique ability to act both as an antineoplastic agent and an appetite stimulant makes it invaluable in improving patient outcomes, nutritional status, and overall quality of life. Patients prescribed MAGRAL 160 should adhere strictly to their healthcare provider’s instructions and report any adverse effects promptly. This medication should always be used under medical supervision to ensure optimal benefits and minimize risks.", "price": 810.0, "discountamount": 243.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2156, "imageuri": "https://productimages.withfloats.com/actual/6891f2a0115b51057b971998.png", "tileimageuri": "https://productimages.withfloats.com/tile/6891f2a0115b51057b971998.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-08-05T12:01:31.195Z", "updatedon": "2025-08-05T12:01:31.195Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/magral-160/2156", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "megestrol acetate 160 mg", "category": "Gynaecology", "tags": [ "megestrol acetate 160 mg" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false } ], "hasmoreitems": false, "isapirequest": false, "totalresults": 27, "query": null, "floatingpoint": null }