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"description": "CITICOTIME PM is a specialized formulation combining Citicoline 500mg and Piracetam 800mg in tablet form, designed to enhance brain health and cognitive functions. This combination harnesses the synergistic effects of two well-researched nootropic agents—citicoline and piracetam tablets—widely used in neurological therapies. Primarily, this medicine supports nerve cell nourishment, protects neurons from damage, and aids in improving memory, focus, and recovery in brain-related conditions such as stroke. Its unique formulation offers neuroprotection and cognitive enhancement, making it an important therapeutic option in treating stroke and other cognitive impairments.\n\nWhat is CITICOTIME PM?\nCITICOTIME PM contains a combination of two active ingredients: Citicoline 500mg, a neuroprotective compound that promotes brain cell repair and function, and Piracetam 800mg, which enhances neuronal communication and cognitive processes. Together, they work to support brain metabolism, improve blood flow, and strengthen cognitive resilience. This formulation is often prescribed to patients recovering from neurological injuries or those experiencing cognitive decline.\n\nUses of Citicoline and Piracetam Tablets\n\nTreatment and recovery support in stroke patients to restore brain function\n\nImprovement of memory, learning ability, and cognitive performance\n\nManagement of neurological disorders such as dementia and Alzheimer's disease\n\nNeuroprotection against brain cell damage caused by trauma or ischemia\n\nEnhancement of mental alertness and reduction of cognitive fatigue\n\nSupport in conditions involving cognitive impairment due to aging or injury\n\nCiticoline + Piracetam is used in the treatment of stroke. Citicoline + Piracetam is a combination of two medicines: Citicoline and Piracetam. Citicoline is a nerve protecting medicine. It works on the brain by nourishing the nerve cells, protects them from damage and improves their survival.\n\nCiticoline and Piracetam Tablets Dosage\nThe recommended dosage depends on the patient's condition, age, and response to therapy. Typically, CITICOTIME PM is taken once or twice daily as prescribed by a healthcare professional. Each tablet delivers Citicoline 500mg and Piracetam 800mg, providing an effective dose for neuroprotection and cognitive support. It should be swallowed whole with water, preferably after meals to reduce gastrointestinal discomfort. Dosage adjustments may be necessary in patients with kidney impairment or other comorbidities. It is critical to follow a doctor's prescribed dosage and not to self-medicate.\n\nSide Effects of Citicoline and Piracetam Tablets\nWhile generally well tolerated, some individuals may experience side effects, which are usually mild and temporary, including:\n\nHeadache\n\nNausea and stomach discomfort\n\nInsomnia or trouble sleeping\n\nNervousness or agitation\n\nDizziness and vertigo\n\nWeight gain in some cases\n\nRare allergic reactions such as skin rash or swelling\n\nChanges in blood pressure or heart rate (typically uncommon)\n\nIf severe side effects or allergic reactions occur, immediate medical attention is advised.\n\nPrecautions Before Using CITICOTIME PM\n\nConsult a doctor before use if you have a history of brain hemorrhage, bleeding disorders, or gastrointestinal ulcers.\n\nUse caution in elderly patients and those with renal or hepatic impairment.\n\nAvoid driving or operating heavy machinery until you know how the medicine affects you.\n\nDo not consume alcohol while taking this medication, as it may increase side effects like drowsiness or nervousness.\n\nInform your healthcare provider if you are pregnant, trying to conceive, or breastfeeding, as safety in these conditions is not fully established.\n\nDo not abruptly stop the medication without medical advice to avoid withdrawal symptoms such as muscle twitching.\n\nDrug Interactions: What Drugs Interact with CITICOTIME PM?\n\nAnticoagulants or blood thinners may increase the risk of bleeding.\n\nOther central nervous system (CNS) stimulants or depressants can enhance side effects like dizziness or drowsiness.\n\nMedications processed by kidneys require careful monitoring as both citicoline and piracetam are primarily excreted renally.\n\nAlcohol consumption can exacerbate side effects, especially sedation and nervousness.\n\nAlways inform your doctor about all medications and supplements you are taking to avoid harmful interactions.\n\nCITICOTIME PM, with citicoline 500mg and piracetam 800mg, is a reliable choice for managing stroke recovery and cognitive disorders by protecting and nourishing nerve cells, improving brain function, and supporting neuronal survival. Proper medical supervision is essential to maximize benefits and minimize risks associated with citicoline and piracetam tablets uses and dosage.",
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"description": "PATRICETAM 800 \nPiracetam (800mg)\nIntroduction:\n\nPATRICETAM 800 contains Piracetam (800 mg), a nootropic agent used to enhance cognitive functions, improve memory, and support neurological health. Piracetam is known for its neuroprotective properties and is widely used to treat cognitive impairments, dementia, and other neurological conditions.\nKey Features and Benefits:\n\nCognitive Enhancement: Piracetam is effective in improving various cognitive functions, including memory, attention, and learning capacity, making it beneficial for individuals with cognitive impairments.\nNeuroprotective Properties: Piracetam provides neuroprotection by enhancing the brain's resilience to damage from oxidative stress and neurotoxins, helping to maintain overall brain health.\nImproved Memory: By enhancing synaptic plasticity and communication between neurons, Piracetam helps improve short-term and long-term memory.\nIncreased Focus and Attention: Piracetam can enhance focus, attention, and mental clarity, which is beneficial for individuals with attention deficits or those needing improved concentration.\nSafe and Well-Tolerated: Piracetam is generally well-tolerated with a favorable safety profile, making it suitable for long-term use.\nDosage and Administration:\n\nInitial Dosage: The typical starting dose of PATRICETAM 800 is 800 mg taken two to three times daily. The dosage may be adjusted by a healthcare provider based on the patient's response to treatment and specific needs.\nMaintenance Dosage: The usual maintenance dose ranges from 2.4 grams to 4.8 grams per day, divided into two or three doses.\nAdministration: The tablet should be taken orally with water, with or without food. It is important to take Piracetam at the same time each day to maintain consistent medication levels in the bloodstream.\nMissed Dose: If a dose is missed, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not take a double dose to make up for a missed one.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order NOW\nhttps://www.sterisonline.com/product/patricetam-800-133600",
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"description": "Iron, Zinc, Folic Acid, and Vitamin B12 Tablets are a comprehensive nutritional formulation designed to support healthy blood formation, enhance immunity, and improve overall vitality. This advanced blend combines four essential micronutrients that play crucial roles in red blood cell development, cognitive function, metabolic balance, and immune health. The formulation is particularly valuable in preventing and managing nutrient deficiencies that can arise due to poor dietary intake, chronic illness, pregnancy, or increased physiological demands.\n\nIron is one of the most vital minerals for the human body, responsible for the production of hemoglobin — the protein in red blood cells that transports oxygen throughout the body. A deficiency in iron often results in fatigue, weakness, dizziness, and reduced physical performance. Complementing iron, Zinc is a key mineral involved in immune function, wound healing, DNA synthesis, and maintaining healthy skin and hair. It also plays a role in protecting cells from oxidative stress and supporting proper hormone function.\n\nFolic Acid (Vitamin B9) is essential for cell growth, DNA formation, and the development of healthy red blood cells. It is especially important for women of childbearing age, as it helps prevent neural tube defects during pregnancy. Vitamin B12 supports neurological health, energy metabolism, and red blood cell production. Together, Folic Acid and Vitamin B12 work synergistically to maintain healthy nerve function and prevent certain types of anemia.\n\nThis combination tablet is formulated to provide balanced supplementation, making it beneficial for individuals with nutritional deficiencies, pregnant and lactating women, adolescents, elderly individuals, and those recovering from illness or surgery.\n\nProduct Uses\n\nThis multi-nutrient tablet is recommended for:\n\nIron-deficiency anemia\nHelps increase hemoglobin levels and restore normal red blood cell production.\n\nFatigue, weakness, and low energy levels\nSupports oxygen transport and metabolic function.\n\nPregnancy and lactation\nEssential for fetal neural development and maintaining maternal health.\n\nImmune system support\nZinc and B12 enhance immunity and help the body fight infections.\n\nNutritional supplementation in adolescents\nSupports rapid growth and cognitive development.\n\nPost-surgery recovery or chronic illness\nHelps rebuild energy and replenish depleted nutrient stores.\n\nVegetarians and vegans\nParticularly beneficial for those at risk of Vitamin B12 deficiency due to dietary limitations.\n\nKey Benefits\n1. Promotes Healthy Blood Formation\n\nIron, Folic Acid, and Vitamin B12 work together to support hemoglobin synthesis and prevent different types of anemia, ensuring adequate oxygen supply to body tissues.\n\n2. Boosts Energy and Reduces Fatigue\n\nBy supporting red blood cell production and metabolic processes, the tablet helps reduce tiredness and improves overall stamina.\n\n3. Enhances Immune Function\n\nZinc strengthens immune response, supports wound healing, and protects cells from damage caused by free radicals.\n\n4. Supports Pregnancy Health\n\nFolic Acid reduces the risk of birth defects, while Iron and Vitamin B12 help maintain healthy blood levels in pregnant women.\n\n5. Improves Cognitive and Nerve Health\n\nVitamin B12 supports nerve integrity, cognitive performance, and mental clarity.\n\n6. Supports Growth and Development\n\nIdeal for adolescents and children undergoing periods of rapid growth requiring additional micronutrients.\n\n7. Maintains Healthy Skin, Hair, and Nails\n\nZinc contributes to tissue repair, while Iron and B12 support healthy cell growth.\n\nPossible Side Effects\n\nWhile generally well tolerated, some individuals may experience:\n\nMild stomach upset or nausea\n\nConstipation or diarrhea\n\nMetallic taste in the mouth (due to iron)\n\nAllergic reactions such as rash or itching (rare)\n\nHeadaches or dizziness in sensitive individuals\n\nDark-colored stools (harmless side effect of iron)\n\nPeople with iron overload disorders, kidney issues, or specific medical conditions should consult a healthcare provider before use.\n\nConclusion\n\nIron, Zinc, Folic Acid, and Vitamin B12 Tablets offer a powerful and well-balanced supplement for improving blood health, boosting immunity, and enhancing overall vitality. This combination supports essential biological processes ranging from oxygen transport and cell growth to neurological function and immune defense. Whether used to prevent anemia, support pregnancy, increase energy levels, or promote healthy development, these tablets serve as a reliable and effective nutritional solution. Incorporating this supplement into daily health routines can contribute significantly to long-term well-being, strength, and resilience.",
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"description": "DRIPHORM E OMEGA is a premium formulation that combines the scientifically proven benefits of Omega-3 Fatty Acids with the antioxidant power of Vitamin E. These softgel capsules are designed to enhance overall wellness by delivering essential nutrients that play a crucial role in heart health, cognitive function, eye protection, and immune support. Omega-3s, especially EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), are vital fatty acids the body cannot produce on its own. Vitamin E adds an extra layer of cellular protection by fighting oxidative stress and supporting skin health.\n\nIdeal for adults seeking improved cardiovascular function, better mental clarity, or enhanced physical well-being, DRIPHORM E OMEGA provides a balanced and effective daily supplementation.\n\nUses\n\nDRIPHORM E OMEGA Softgel Capsules are used for:\n\nMaintaining healthy heart function and cholesterol levels\n\nEnhancing brain health, memory, and focus\n\nSupporting eye health and protecting vision\n\nReducing inflammation and improving joint mobility\n\nStrengthening immunity and overall resilience\n\nSupporting skin nourishment and delaying signs of aging\n\nManaging nutritional deficiencies related to inadequate Omega-3 intake\n\nThese uses make the capsules suitable for people with busy lifestyles, older adults, and individuals seeking comprehensive nutritional support.\n\nBenefits\n1. Promotes Heart Health\n\nOmega-3 fatty acids help maintain normal triglyceride levels and support healthy blood circulation. Their anti-inflammatory properties contribute to improved cardiovascular performance and long-term heart protection.\n\n2. Enhances Brain and Cognitive Function\n\nDHA is essential for optimal brain structure and performance. Regular intake supports mental clarity, sharper focus, and improved memory function—beneficial for students, working professionals, and aging individuals.\n\n3. Strengthens Eye Health\n\nOmega-3s help protect the retina and support overall visual acuity. Consistent use may reduce eye strain and dryness, especially for individuals with prolonged screen exposure.\n\n4. Boosts Skin, Hair & Nail Health\n\nVitamin E offers powerful antioxidant support that helps slow down skin aging, improve skin elasticity, and protect against environmental damage. Combined with Omega-3s, it nourishes skin from within, reduces dryness, and promotes healthy hair growth.\n\n5. Reduces Inflammation & Supports Joint Mobility\n\nOmega-3 fatty acids are known for reducing inflammation, helping relieve joint stiffness and improving flexibility. This makes DRIPHORM E OMEGA ideal for athletes, fitness enthusiasts, and individuals with joint discomfort.\n\n6. Antioxidant Protection & Immunity Boost\n\nVitamin E protects cells from oxidative damage and enhances immune response. With regular intake, the body becomes more resilient to stress and environmental toxins.\n\nDosage\n\nTake DRIPHORM E OMEGA as advised by your physician or healthcare professional. A common recommendation is one softgel capsule once or twice daily, preferably with meals to improve absorption. Do not exceed the recommended dosage unless directed by a healthcare provider.\n\nSide Effects\n\nAlthough generally safe and well tolerated, some individuals may experience:\n\nMild digestive discomfort\n\nFishy burps or aftertaste\n\nNausea\n\nLoose stools\n\nHeadache\n\nThese side effects are usually temporary. If symptoms persist or worsen, discontinue use and consult your doctor.\n\nPrecautions and Warning\n\nPregnant or breastfeeding women should seek medical advice before use.\n\nPeople with fish allergies should avoid this product or consult a doctor.\n\nIndividuals with bleeding disorders, or those taking blood thinners, should use the product under medical supervision.\n\nKeep out of reach of children.\n\nStore in a cool, dry place away from moisture and direct sunlight.\n\nDo not use if the seal is broken or the product has expired.\n\nConsult your physician before use if you have underlying medical conditions or are taking long-term medications.\n\nConclusion\n\nDRIPHORM E OMEGA Omega-3 Fatty Acid and Vitamin E Softgel Capsules offer a complete wellness solution by supporting heart health, boosting brain function, protecting eyesight, and enhancing immunity. With its powerful antioxidant and anti-inflammatory benefits, this supplement is ideal for anyone seeking improved vitality, balanced nutrition, and long-term health support. Make DRIPHORM E OMEGA a part of your daily routine to nourish your body, elevate your energy, and strengthen your overall well-being.",
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"name": "Miltefosine Capsules",
"description": "Miltefosine Capsules are an important oral medication widely recognized for their effectiveness in treating Visceral Leishmaniasis (Kala-azar), Cutaneous Leishmaniasis, and certain protozoal infections. As the first and only oral drug approved for the treatment of Leishmaniasis, Miltefosine has significantly transformed patient care by offering a convenient and reliable alternative to painful injectable therapies. The medication belongs to the class of alkylphosphocholine drugs and is known for its potent antiparasitic and cytotoxic actions.\n\nMiltefosine Capsules are typically prescribed by healthcare professionals when a confirmed diagnosis of Leishmaniasis has been made, or when the patient is not responding adequately to other modes of therapy. Its high absorption rate, ease of administration, and consistent therapeutic activity make it a cornerstone in parasitic infection management across endemic regions.\n\nWhat Are Miltefosine Capsules?\n\nMiltefosine is an oral antiparasitic medication designed to eliminate Leishmania parasites by disrupting their cell membranes and metabolic functions. It was originally studied for anticancer activities but later found to be highly effective against various Leishmania species. Unlike conventional treatment options that require hospitalization and injections, Miltefosine offers a non-invasive, at-home oral therapy option, improving both patient comfort and compliance.\n\nMiltefosine Capsules are generally marketed in different strengths such as 50 mg. The duration of treatment usually ranges between 28–30 days depending on the medical condition and severity.\n\nUses of Miltefosine Capsules\n\nMiltefosine Capsules are primarily prescribed for:\n\n1. Visceral Leishmaniasis (Kala-azar)\n\nThis is a severe, life-threatening parasitic disease affecting internal organs such as the spleen, liver, and bone marrow. Miltefosine is considered one of the most effective oral treatment options for Kala-azar and is widely used in India and other tropical regions where the disease is endemic.\n\n2. Cutaneous Leishmaniasis\n\nIt causes skin lesions, ulcers, and disfiguring scars. Miltefosine works by targeting the parasite in skin tissues, promoting faster healing and reducing complications.\n\n3. Mucocutaneous Leishmaniasis\n\nThough less common, this form affects mucous membranes of the nose, mouth, and throat. Miltefosine plays a major role in preventing progressive tissue destruction.\n\n4. Off-Label Uses\n\nIn some cases, doctors may prescribe Miltefosine for:\n\nCertain protozoal infections\n\nAmoebic keratitis (rare condition affecting the eye)\n\nParasitic infections resistant to other treatments\n\nHowever, these uses should only be followed under strict medical supervision.\n\nHow Miltefosine Works\n\nMiltefosine acts directly on parasitic cells by:\n\nDisrupting cell membrane integrity\n\nInterfering with phospholipid metabolism\n\nTriggering apoptosis-like cell death in parasites\n\nWeakening parasite reproduction and survival\n\nThis multi-target mechanism makes Miltefosine one of the most powerful oral antiparasitic medications available today.\n\nKey Benefits of Miltefosine Capsules\n1. Highly Effective Oral Treatment\n\nUnlike older treatments requiring multiple injections, Miltefosine provides a simple oral dosage, eliminating the need for hospitalization or painful procedures.\n\n2. Excellent Patient Compliance\n\nThe convenience of taking capsules at home significantly improves adherence to treatment, especially in rural or resource-limited areas.\n\n3. Strong Activity Against Leishmania Species\n\nMiltefosine’s broad-spectrum antiparasitic properties make it effective against several strains of Leishmania responsible for different clinical presentations of the disease.\n\n4. Lower Risk of Severe Treatment Complications\n\nCompared to traditional injectable therapies like antimonials, Miltefosine has a better safety profile when used under medical supervision.\n\n5. Reduces Disease Transmission\n\nBy effectively eliminating parasites from the body, Miltefosine helps reduce the overall disease burden in endemic communities.\n\n6. Faster Healing of Skin Lesions\n\nPatients with Cutaneous Leishmaniasis experience faster recovery, reduced lesion size, and minimal scarring when treatment is taken on time.\n\n7. Well-Studied and Recommended\n\nMiltefosine is recommended by WHO and national health authorities in many countries as a frontline treatment for Kala-azar.\n\nPossible Side Effects of Miltefosine Capsules\n\nWhile generally well tolerated, Miltefosine may cause certain side effects. Most of these are mild to moderate and subside as the body adapts to the medication.\n\nCommon Side Effects\n\nNausea and vomiting\n\nDiarrhea\n\nAbdominal discomfort\n\nLoss of appetite\n\nTemporary weakness or fatigue\n\nModerate Side Effects\n\nElevated liver enzymes\n\nMild kidney function changes\n\nSkin reactions such as redness or itching\n\nSevere, But Less Common Side Effects\n\nNephrotoxicity (kidney-related issues)\n\nHepatotoxicity (liver-related issues)\n\nSevere gastrointestinal upset\n\nVision-related disturbances in very rare cases\n\nImportant Warning for Women\n\nMiltefosine is NOT recommended during pregnancy as it can cause fetal harm. Women of childbearing age must use reliable contraception during treatment and for at least 3 months after therapy.\n\nPrecautions\n\nPatients with the following conditions should use Miltefosine cautiously:\n\nLiver or kidney disease\n\nPregnancy or breastfeeding\n\nSevere dehydration\n\nUncontrolled vomiting or diarrhea\n\nAlways follow the dosage exactly as prescribed by a healthcare professional.\n\nConclusion\n\nMiltefosine Capsules have revolutionized the treatment of various forms of Leishmaniasis by offering a powerful, effective, and convenient oral therapy option. Their ability to target parasitic infections through multiple mechanisms makes them a trusted solution in endemic regions. Whether used for Visceral, Cutaneous, or Mucocutaneous Leishmaniasis, Miltefosine provides significant therapeutic benefits, faster recovery, and improved patient compliance.",
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"name": "Nicorandil Tablets 5mg",
"description": "Nicorandil Tablets 5 mg is a vasodilatory anti-anginal medication widely prescribed for the management and prevention of angina pectoris (chest pain) associated with coronary artery disease (CAD). Angina results from an imbalance between the heart’s oxygen demand and supply due to restricted blood flow in the coronary arteries. Nicorandil offers a dual mechanism of action — acting both as a nitrate-like vasodilator and a potassium channel opener, making it unique among anti-anginal agents.\n\nBy improving oxygen delivery to the myocardium and reducing cardiac workload, Nicorandil 5 mg Tablets provide effective relief from anginal pain and reduce the frequency and severity of ischemic episodes. It is also beneficial in preventing future attacks, improving exercise tolerance, and enhancing the overall quality of life in patients with chronic stable angina.\n\nComposition\n\nEach tablet contains:\n\nNicorandil IP – 5 mg\n\nExcipients – q.s.\n\nNicorandil tablets are available in film-coated form to ensure stability, easy swallowing, and optimal absorption. They are manufactured in compliance with Good Manufacturing Practices (GMP) standards to ensure safety, purity, and efficacy.\n\nPharmacological Action / Mechanism of Action\n\nNicorandil exhibits a dual mechanism that makes it distinct among anti-anginal drugs:\n\nNitrate-Like Effect:\nNicorandil acts as a nitric oxide (NO) donor. Nitric oxide activates guanylate cyclase, increasing cyclic GMP (cGMP) levels in vascular smooth muscle. This leads to relaxation of blood vessels, particularly veins and large arteries, thereby reducing preload and afterload on the heart. This nitrate-like activity lowers myocardial oxygen demand.\n\nPotassium Channel Opening Effect:\nNicorandil opens ATP-sensitive potassium (KATP) channels in vascular smooth muscle, resulting in arteriolar vasodilation. This increases coronary blood flow and improves oxygen supply to ischemic heart tissues.\n\nTogether, these effects reduce cardiac workload, enhance coronary perfusion, and prevent anginal pain by correcting the oxygen supply-demand mismatch in the heart muscle.\n\nUses and Indications\n\nNicorandil Tablets 5 mg are indicated for the treatment and prevention of angina pectoris in adults, particularly:\n\nChronic Stable Angina:\n\nHelps reduce the frequency and severity of chest pain associated with exertion or emotional stress.\n\nProphylaxis of Angina Attacks:\n\nUsed regularly to prevent anginal episodes, especially in patients with known coronary artery disease.\n\nAdjunct Therapy in Ischemic Heart Disease (IHD):\n\nCan be used alongside beta-blockers, calcium channel blockers, or antiplatelet drugs for enhanced symptom control and long-term protection.\n\nImprovement of Exercise Tolerance:\n\nReduces the likelihood of anginal pain during physical activity, enabling patients to perform daily tasks comfortably.\n\nIn some clinical cases, Nicorandil is also considered for post-myocardial infarction recovery, as it improves coronary perfusion, although this is at the discretion of a cardiologist.\n\nDosage and Administration\n\nRecommended Starting Dose: 5 mg to 10 mg twice daily.\n\nMaintenance Dose: May be increased gradually to 10–20 mg twice daily, depending on clinical response and tolerance.\n\nThe tablets should be swallowed whole with water, preferably at the same times each day.\n\nNicorandil should not be stopped abruptly; dosage tapering is recommended to avoid rebound angina.\n\nAlways follow the dosage instructions provided by the physician.\n\nKey Benefits\n\nDual Mechanism for Comprehensive Relief:\nCombines nitrate-like and potassium channel-opening properties for both arterial and venous dilation, providing superior protection against anginal attacks.\n\nImproves Coronary Blood Flow:\nDilates coronary arteries, increasing oxygen delivery to ischemic myocardial tissues.\n\nReduces Cardiac Workload:\nBy decreasing preload (venous return) and afterload (arterial resistance), Nicorandil minimizes the heart’s oxygen consumption.\n\nRapid Onset of Action:\nNicorandil acts within a short duration, offering quick relief from anginal discomfort.\n\nPrevents Future Angina Episodes:\nRegular use helps maintain steady control of chest pain, improving exercise capacity and quality of life.\n\nCompatible with Other Cardiac Medications:\nCan be safely used alongside antiplatelet agents, beta-blockers, ACE inhibitors, and statins as part of comprehensive cardiac care.\n\nFavorable Safety Profile:\nCompared to nitrates, Nicorandil carries a lower risk of tolerance development, making it suitable for long-term therapy.\n\nEnhances Myocardial Protection:\nNicorandil’s KATP channel activation provides additional cardioprotective effects by improving microvascular blood flow and limiting ischemic damage during stress.\n\nPrecautions and Warnings\n\nAlthough Nicorandil is generally well-tolerated, certain precautions are advised:\n\nHypotension:\nNicorandil may cause a drop in blood pressure due to vasodilation. Caution is advised in patients with hypotension or dehydration.\n\nConcurrent Use with Nitrates:\nShould not be used together with other nitrate medications to avoid severe hypotension.\n\nOral or Gastrointestinal Ulcers:\nRarely, Nicorandil may cause ulcerations in the mouth, intestines, or skin. Treatment should be discontinued if ulceration occurs.\n\nPatients with Low Blood Volume:\nUse cautiously in individuals with hypovolemia or those on diuretics.\n\nDriving and Machinery:\nDizziness or light-headedness may occur; avoid driving until effects are known.\n\nPregnancy and Lactation:\nShould be used only if prescribed by a physician when the potential benefits outweigh the risks.\n\nPossible Side Effects\n\nNicorandil is generally safe but may cause some side effects, particularly at the start of therapy or with higher doses. Common and rare adverse reactions include:\n\nCommon Side Effects:\n\nHeadache (due to vasodilation)\n\nFlushing or warmth sensation\n\nDizziness or light-headedness\n\nNausea or mild stomach upset\n\nFatigue or weakness\n\nLess Common / Rare Side Effects:\n\nHypotension (low blood pressure)\n\nPalpitations or tachycardia\n\nMouth ulcers, anal ulcers, or skin ulceration (uncommon but serious — discontinue if occurs)\n\nRash or allergic reaction\n\nVisual disturbances (rare and usually reversible)\n\nIf any severe reaction or persistent discomfort occurs, medical attention should be sought promptly.\n\nDrug Interactions\n\nAvoid concomitant use with nitrates or phosphodiesterase type-5 inhibitors (e.g., Sildenafil, Tadalafil), as it may cause a dangerous fall in blood pressure.\n\nCaution with antihypertensive drugs or diuretics, which may enhance hypotensive effects.\n\nAlcohol consumption can potentiate dizziness or hypotension and should be limited.\n\nStorage and Handling\n\nStore below 30°C, protected from moisture and direct sunlight.\n\nKeep out of reach of children.\n\nDo not use tablets past the expiry date or if the packaging is damaged.\n\nConclusion\n\nNicorandil Tablets 5 mg offer a modern and effective approach to managing angina pectoris, providing reliable relief through their dual-action mechanism. By combining nitrate-like vasodilation with potassium channel opening, Nicorandil ensures both oxygen supply improvement and reduction of cardiac workload — the cornerstone of angina management.\n\nIt is well-tolerated, fast-acting, and suitable for long-term therapy, making it a preferred choice for patients with chronic stable angina. Regular use under medical supervision helps reduce the frequency of chest pain, improve physical endurance, and enhance the overall quality of life in individuals with coronary artery disease.",
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"name": "Paracetamol Infusion ip",
"description": "Paracetamol Infusion IP is a sterile, non-pyrogenic, and clear solution of Paracetamol (Acetaminophen) formulated for intravenous administration. It is primarily used for the management of pain and fever when oral or rectal routes are not suitable, such as in hospitalized or post-operative patients. Recognized as one of the most widely used analgesic and antipyretic medications, Paracetamol Infusion IP offers rapid onset of action, consistent therapeutic effects, and excellent patient tolerance.\n\nThis formulation ensures precise and controlled delivery of Paracetamol directly into the bloodstream, allowing for faster relief and improved bioavailability compared to oral administration.\n\nComposition\n\nEach 100 mL of Paracetamol Infusion IP typically contains:\n\nParacetamol IP – 1000 mg (1% w/v)\n\nExcipients – as required for stability and isotonicity\n\nWater for Injection – q.s. to 100 mL\n\nThe infusion is usually supplied in ready-to-use glass or plastic bottles or flexible bags, ensuring sterility and ease of use in hospital settings.\n\nMechanism of Action\n\nParacetamol (acetaminophen) exerts its therapeutic effects primarily through central inhibition of prostaglandin synthesis. Unlike nonsteroidal anti-inflammatory drugs (NSAIDs), Paracetamol has minimal peripheral anti-inflammatory activity, making it a safer option for patients with gastrointestinal or platelet-related concerns.\n\nThe drug acts by:\n\nInhibiting the cyclooxygenase (COX) enzymes, particularly COX-3, within the central nervous system, thereby reducing the synthesis of prostaglandins responsible for fever and pain.\n\nModulating the endocannabinoid system and serotonergic pathways, enhancing its analgesic potential.\n\nAs a result, Paracetamol Infusion IP provides effective fever reduction (antipyretic) and pain relief (analgesic) without significant gastrointestinal irritation or bleeding risks.\n\nIndications and Uses\n\nParacetamol Infusion IP is indicated for:\n\nManagement of Fever (Pyrexia):\n\nReduces elevated body temperature in adults and children.\n\nSuitable for patients unable to take oral medication due to nausea, vomiting, or unconsciousness.\n\nRelief of Mild to Moderate Pain:\n\nEffective in conditions like headaches, dental pain, menstrual cramps, and musculoskeletal pain.\n\nCommonly used as part of multimodal pain management after surgical procedures.\n\nPost-Operative and Trauma Pain:\n\nProvides fast, reliable pain relief in surgical recovery and trauma cases where oral medication is not feasible.\n\nAdjunct Therapy:\n\nCan be used alongside opioids to enhance analgesic effect and reduce opioid requirements.\n\nDosage and Administration\n\nAdults and adolescents (>50 kg): 1 g every 6 hours, not exceeding 4 g per day.\n\nAdults and adolescents (<50 kg): Dose adjusted based on body weight, typically 15 mg/kg every 6 hours.\n\nChildren (≥10 kg): 15 mg/kg per dose every 6 hours.\n\nThe infusion should be administered over 15 minutes, using aseptic technique. Paracetamol Infusion should not be mixed with other drugs in the same IV line unless compatibility is established.\n\nKey Benefits\n\nRapid Onset of Action:\nIntravenous administration ensures faster absorption and onset of relief compared to oral or rectal forms.\n\nHigh Bioavailability:\nSince it bypasses gastrointestinal metabolism, almost the entire dose reaches systemic circulation, providing consistent therapeutic effect.\n\nConvenience in Critical Care:\nIdeal for patients who are unconscious, post-surgery, or unable to tolerate oral medications.\n\nSafe and Well-Tolerated:\nHas minimal gastrointestinal side effects and no significant effect on platelets or renal function when used within the recommended dose range.\n\nEffective Multimodal Pain Relief:\nEnhances pain control when combined with opioids, allowing reduced opioid dosage and minimizing associated risks.\n\nStable Formulation:\nThe isotonic and sterile composition ensures patient safety, stability, and reduced risk of contamination.\n\nSuitable for Broad Patient Demographics:\nCan be used in adults, elderly patients, and children under proper medical supervision.\n\nPrecautions and Warnings\n\nWhile Paracetamol Infusion IP is generally safe, the following precautions should be observed:\n\nLiver Impairment:\nUse with caution in patients with hepatic insufficiency, chronic alcoholism, or pre-existing liver disease, as Paracetamol is primarily metabolized in the liver.\n\nRenal Impairment:\nDosage adjustment may be required in severe renal dysfunction.\n\nAvoid Overdose:\nExceeding the recommended dose can lead to severe liver toxicity and, in extreme cases, hepatic failure.\n\nDrug Interactions:\nConcomitant use with other Paracetamol-containing medications increases risk of overdose.\nCaution when used with hepatotoxic drugs or alcohol.\n\nPregnancy and Lactation:\nGenerally considered safe when used under medical supervision, though benefits should outweigh potential risks.\n\nPossible Side Effects\n\nAlthough rare and usually mild, Paracetamol Infusion IP may cause:\n\nAllergic Reactions:\nSkin rash, itching, urticaria, or swelling.\n\nHypotension:\nA transient drop in blood pressure may occur during infusion in some patients.\n\nLiver Toxicity:\nOverdose or prolonged use can lead to hepatocellular injury or elevated liver enzymes.\n\nInjection Site Reactions:\nMild pain, redness, or inflammation at the infusion site.\n\nBlood Disorders (Very Rare):\nThrombocytopenia or leukopenia may occur in extremely rare cases.\n\nIf any severe reaction such as jaundice, persistent vomiting, or allergic swelling occurs, medical attention should be sought immediately.\n\nStorage and Handling\n\nStore below 30°C, protected from light and freezing.\n\nDo not use if the solution appears cloudy or contains particles.\n\nSingle-use only; discard any unused portion after opening.\n\nConclusion\n\nParacetamol Infusion IP stands as a trusted, fast-acting, and safe intravenous formulation of one of the most widely used analgesic and antipyretic agents worldwide. Its ability to deliver rapid and predictable pain and fever relief makes it invaluable in hospitals, emergency care, and post-surgical settings.\n\nWith its favorable safety profile, high efficacy, and compatibility with multimodal pain management strategies, Paracetamol Infusion IP continues to be a first-line choice for clinicians seeking a reliable and well-tolerated solution for pain and fever management.",
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