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{ "products": [ { "_id": "69142bf71d499513a92e5772", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Nicorandil Tablets 5mg", "description": "Nicorandil Tablets 5 mg is a vasodilatory anti-anginal medication widely prescribed for the management and prevention of angina pectoris (chest pain) associated with coronary artery disease (CAD). Angina results from an imbalance between the heart’s oxygen demand and supply due to restricted blood flow in the coronary arteries. Nicorandil offers a dual mechanism of action — acting both as a nitrate-like vasodilator and a potassium channel opener, making it unique among anti-anginal agents.\n\nBy improving oxygen delivery to the myocardium and reducing cardiac workload, Nicorandil 5 mg Tablets provide effective relief from anginal pain and reduce the frequency and severity of ischemic episodes. It is also beneficial in preventing future attacks, improving exercise tolerance, and enhancing the overall quality of life in patients with chronic stable angina.\n\nComposition\n\nEach tablet contains:\n\nNicorandil IP – 5 mg\n\nExcipients – q.s.\n\nNicorandil tablets are available in film-coated form to ensure stability, easy swallowing, and optimal absorption. They are manufactured in compliance with Good Manufacturing Practices (GMP) standards to ensure safety, purity, and efficacy.\n\nPharmacological Action / Mechanism of Action\n\nNicorandil exhibits a dual mechanism that makes it distinct among anti-anginal drugs:\n\nNitrate-Like Effect:\nNicorandil acts as a nitric oxide (NO) donor. Nitric oxide activates guanylate cyclase, increasing cyclic GMP (cGMP) levels in vascular smooth muscle. This leads to relaxation of blood vessels, particularly veins and large arteries, thereby reducing preload and afterload on the heart. This nitrate-like activity lowers myocardial oxygen demand.\n\nPotassium Channel Opening Effect:\nNicorandil opens ATP-sensitive potassium (KATP) channels in vascular smooth muscle, resulting in arteriolar vasodilation. This increases coronary blood flow and improves oxygen supply to ischemic heart tissues.\n\nTogether, these effects reduce cardiac workload, enhance coronary perfusion, and prevent anginal pain by correcting the oxygen supply-demand mismatch in the heart muscle.\n\nUses and Indications\n\nNicorandil Tablets 5 mg are indicated for the treatment and prevention of angina pectoris in adults, particularly:\n\nChronic Stable Angina:\n\nHelps reduce the frequency and severity of chest pain associated with exertion or emotional stress.\n\nProphylaxis of Angina Attacks:\n\nUsed regularly to prevent anginal episodes, especially in patients with known coronary artery disease.\n\nAdjunct Therapy in Ischemic Heart Disease (IHD):\n\nCan be used alongside beta-blockers, calcium channel blockers, or antiplatelet drugs for enhanced symptom control and long-term protection.\n\nImprovement of Exercise Tolerance:\n\nReduces the likelihood of anginal pain during physical activity, enabling patients to perform daily tasks comfortably.\n\nIn some clinical cases, Nicorandil is also considered for post-myocardial infarction recovery, as it improves coronary perfusion, although this is at the discretion of a cardiologist.\n\nDosage and Administration\n\nRecommended Starting Dose: 5 mg to 10 mg twice daily.\n\nMaintenance Dose: May be increased gradually to 10–20 mg twice daily, depending on clinical response and tolerance.\n\nThe tablets should be swallowed whole with water, preferably at the same times each day.\n\nNicorandil should not be stopped abruptly; dosage tapering is recommended to avoid rebound angina.\n\nAlways follow the dosage instructions provided by the physician.\n\nKey Benefits\n\nDual Mechanism for Comprehensive Relief:\nCombines nitrate-like and potassium channel-opening properties for both arterial and venous dilation, providing superior protection against anginal attacks.\n\nImproves Coronary Blood Flow:\nDilates coronary arteries, increasing oxygen delivery to ischemic myocardial tissues.\n\nReduces Cardiac Workload:\nBy decreasing preload (venous return) and afterload (arterial resistance), Nicorandil minimizes the heart’s oxygen consumption.\n\nRapid Onset of Action:\nNicorandil acts within a short duration, offering quick relief from anginal discomfort.\n\nPrevents Future Angina Episodes:\nRegular use helps maintain steady control of chest pain, improving exercise capacity and quality of life.\n\nCompatible with Other Cardiac Medications:\nCan be safely used alongside antiplatelet agents, beta-blockers, ACE inhibitors, and statins as part of comprehensive cardiac care.\n\nFavorable Safety Profile:\nCompared to nitrates, Nicorandil carries a lower risk of tolerance development, making it suitable for long-term therapy.\n\nEnhances Myocardial Protection:\nNicorandil’s KATP channel activation provides additional cardioprotective effects by improving microvascular blood flow and limiting ischemic damage during stress.\n\nPrecautions and Warnings\n\nAlthough Nicorandil is generally well-tolerated, certain precautions are advised:\n\nHypotension:\nNicorandil may cause a drop in blood pressure due to vasodilation. Caution is advised in patients with hypotension or dehydration.\n\nConcurrent Use with Nitrates:\nShould not be used together with other nitrate medications to avoid severe hypotension.\n\nOral or Gastrointestinal Ulcers:\nRarely, Nicorandil may cause ulcerations in the mouth, intestines, or skin. Treatment should be discontinued if ulceration occurs.\n\nPatients with Low Blood Volume:\nUse cautiously in individuals with hypovolemia or those on diuretics.\n\nDriving and Machinery:\nDizziness or light-headedness may occur; avoid driving until effects are known.\n\nPregnancy and Lactation:\nShould be used only if prescribed by a physician when the potential benefits outweigh the risks.\n\nPossible Side Effects\n\nNicorandil is generally safe but may cause some side effects, particularly at the start of therapy or with higher doses. Common and rare adverse reactions include:\n\nCommon Side Effects:\n\nHeadache (due to vasodilation)\n\nFlushing or warmth sensation\n\nDizziness or light-headedness\n\nNausea or mild stomach upset\n\nFatigue or weakness\n\nLess Common / Rare Side Effects:\n\nHypotension (low blood pressure)\n\nPalpitations or tachycardia\n\nMouth ulcers, anal ulcers, or skin ulceration (uncommon but serious — discontinue if occurs)\n\nRash or allergic reaction\n\nVisual disturbances (rare and usually reversible)\n\nIf any severe reaction or persistent discomfort occurs, medical attention should be sought promptly.\n\nDrug Interactions\n\nAvoid concomitant use with nitrates or phosphodiesterase type-5 inhibitors (e.g., Sildenafil, Tadalafil), as it may cause a dangerous fall in blood pressure.\n\nCaution with antihypertensive drugs or diuretics, which may enhance hypotensive effects.\n\nAlcohol consumption can potentiate dizziness or hypotension and should be limited.\n\nStorage and Handling\n\nStore below 30°C, protected from moisture and direct sunlight.\n\nKeep out of reach of children.\n\nDo not use tablets past the expiry date or if the packaging is damaged.\n\nConclusion\n\nNicorandil Tablets 5 mg offer a modern and effective approach to managing angina pectoris, providing reliable relief through their dual-action mechanism. By combining nitrate-like vasodilation with potassium channel opening, Nicorandil ensures both oxygen supply improvement and reduction of cardiac workload — the cornerstone of angina management.\n\nIt is well-tolerated, fast-acting, and suitable for long-term therapy, making it a preferred choice for patients with chronic stable angina. Regular use under medical supervision helps reduce the frequency of chest pain, improve physical endurance, and enhance the overall quality of life in individuals with coronary artery disease.", "price": 381.0, "discountamount": 115.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2202, "imageuri": "https://productimages.withfloats.com/actual/69142c03b53db80943abd33d.png", "tileimageuri": "https://productimages.withfloats.com/tile/69142c03b53db80943abd33d.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-12T06:40:55.795Z", "updatedon": "2025-12-09T05:59:32.564Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/nicorandil-tablets-5mg/2202", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MAYORANDIL 5 ", "category": "CARDIOLOGYRANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "68d51d9a26579f4bc195771a", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Glimepiride IP1 mg, Voglibose IP 0.2 MG & Metformin Hydrochloride IP 500 mg ", "description": "GLIMITERIS MV1 0.2 is an advanced fixed-dose combination (FDC) medication designed for adults with Type 2 Diabetes Mellitus (T2DM) who require more than lifestyle modifications or single/dual therapy to maintain optimal blood sugar levels. This innovative formulation brings together the power of three well-established antidiabetic agents—Glimepiride (1 mg), Voglibose (0.2 mg), and Metformin Hydrochloride SR (500 mg)—to provide comprehensive glycemic control.\n\nIt is particularly effective for patients struggling with postprandial hyperglycemia, fasting glucose regulation, and HbA1c reduction, making it a preferred choice in cases of poorly controlled diabetes.\n\n \n\nMechanism of Action\nThe therapeutic benefit of GLIMITERIS MV1 0.2 comes from the unique synergy of its three components, each targeting different aspects of glucose metabolism:\n\n1. Glimepiride (1 mg) – Sulfonylurea\nStimulates insulin secretion by activating pancreatic beta cells.\n\nProvides a long-lasting effect with comparatively lower hypoglycemia risk than older sulfonylureas.\n\nHelps reduce both fasting and postprandial glucose levels.\n\n2. Voglibose (0.2 mg) – Alpha-Glucosidase Inhibitor\nDelays the breakdown and absorption of carbohydrates in the intestine.\n\nMinimizes post-meal glucose spikes (PPBG).\n\nActs locally in the gut and has minimal systemic absorption, which reduces systemic side effects.\n\n3. Metformin Hydrochloride SR (500 mg) – Biguanide\nDecreases hepatic glucose production (gluconeogenesis).\n\nImproves peripheral insulin sensitivity, enhancing glucose uptake in muscles.\n\nDoes not cause hypoglycemia on its own.\n\nThe sustained-release (SR) formulation ensures extended control and reduces gastrointestinal side effects.\n\n \n\nIndications\nGLIMITERIS MV1 0.2 is indicated for:\n\nAdults with Type 2 Diabetes Mellitus.\n\nPatients inadequately controlled with monotherapy or dual therapy.\n\nManagement of fasting and postprandial hyperglycemia.\n\nLong-term HbA1c reduction as part of a comprehensive diabetes care plan.\n\n \n\nKey Benefits\n✅ Comprehensive Blood Sugar Control – Acts on fasting, post-meal, and long-term HbA1c levels.\n✅ Postprandial Spike Management – Voglibose effectively controls carbohydrate-induced sugar surges.\n✅ Reduced Pill Burden – Combines three medicines into a single tablet.\n✅ Lower Hypoglycemia Risk – Metformin and Voglibose balance out Glimepiride’s insulin-secreting effect.\n✅ Weight Management Support – Metformin may promote modest weight loss or prevent weight gain.\n✅ Improved Tolerability – SR formulation of Metformin enhances gastrointestinal comfort.\n\n \n\nDosage and Administration\nRecommended dose: One tablet once or twice daily with meals, or as directed by the physician.\n\nAdministration tips:\n\nTake with the first bite of a main meal to maximize Voglibose’s effect.\n\nSwallow whole with water; do not crush or chew the SR tablet.\n\nDose adjustments: Based on blood sugar monitoring, clinical response, and renal/hepatic function.\n\n \n\nContraindications\nGLIMITERIS MV1 0.2 is not suitable for patients with:\n\nType 1 diabetes or diabetic ketoacidosis.\n\nSevere renal impairment (eGFR <30 mL/min/1.73 m²).\n\nHepatic dysfunction.\n\nSevere gastrointestinal diseases.\n\nHistory of lactic acidosis.\n\nHypersensitivity to Glimepiride, Voglibose, or Metformin.\n\nPregnancy and lactation (unless strictly advised by a physician).\n\n \n\nWarnings and Precautions\nHypoglycemia: Risk is higher when combined with other antidiabetics or with missed meals.\n\nLactic Acidosis: A rare but life-threatening effect of Metformin—renal function monitoring is essential.\n\nGI Side Effects: Voglibose and Metformin may cause bloating, flatulence, or diarrhea (usually temporary).\n\nVitamin B12 Monitoring: Long-term Metformin use may reduce B12 absorption.\n\nLiver and Kidney Function: Regular monitoring is recommended for safe long-term use.\n\n \n\nAdverse Effects\nCommon:\nGlimepiride: Mild hypoglycemia, dizziness, slight weight gain.\n\nVoglibose: Gas, abdominal discomfort, mild diarrhea.\n\nMetformin SR: Nausea, bloating, metallic taste, loose stools.\n\nRare but Serious:\nLactic acidosis (from Metformin).\n\nSevere hypoglycemia (especially if meals are skipped).\n\nAllergic reactions such as rash, itching, or swelling.\n\nElevated liver enzymes.\n\nSeek medical attention if symptoms such as rapid breathing, confusion, severe fatigue, or muscle pain occur.\n\n \n\nDrug Interactions\nIncreased hypoglycemia risk: With insulin, beta-blockers, and sulfonylureas.\n\nReduced Metformin efficacy: With corticosteroids, estrogens, and diuretics.\n\nLactic acidosis risk: Higher with alcohol or iodinated contrast agents. ", "price": 263.0, "discountamount": 80.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2182, "imageuri": "https://productimages.withfloats.com/actual/68d51d9cdf1a4ca2c252370a.png", "tileimageuri": "https://productimages.withfloats.com/tile/68d51d9cdf1a4ca2c252370a.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-09-25T10:46:50.098Z", "updatedon": "2025-12-02T06:31:16.051Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/glimepiride-ip1-mg-voglibose-ip-0-2-mg-metformin-hydrochloride-ip-500-mg-/2182", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "GLIMITERIS MV1 0.2", "category": "", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "68bc22e83c3803d861d696a9", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Cefpodoxime Proxetil Tablets IP 200 mg", "description": "CEPHODOXIAA 200 is a broad-spectrum oral antibiotic from Steris Healthcare Pvt. Ltd., containing Cefpodoxime Proxetil 200 mg. It belongs to the third-generation cephalosporin class, designed to combat a wide range of bacterial infections effectively. With its high bioavailability, safety profile, and proven efficacy, it is trusted in clinical practice for managing both respiratory and urinary tract infections.\nUsage and Benefits\nCEPHODOXIAA 200 is prescribed for the treatment of bacterial infections caused by susceptible microorganisms, including:\n\nRespiratory tract infections (bronchitis, pneumonia, sinusitis, pharyngitis, tonsillitis)\n\nUrinary tract infections (cystitis, pyelonephritis)\n\nEar infections (otitis media)\n\nSkin and soft tissue infections\n\nCertain sexually transmitted infections (like gonorrhea)\n\nCommunity-acquired infections where cephalosporins are indicated\n\nBenefits:\n\nBroad-spectrum antibacterial activity against gram-positive and gram-negative organisms\n\nHigh tolerability and oral bioavailability\n\nConvenient twice-daily dosing\n\nEffective alternative when resistance to other antibiotics is suspected\n\nDosage and Administration\nAdults: Typical dose is 200 mg every 12 hours, depending on the severity of the infection.\n\nChildren: Dose is weight-adjusted, usually prescribed in suspension form.\n\nDuration: Treatment typically lasts 5–14 days depending on the infection type and clinical response.\n\nAdministration Tips:\n\nTake with food to enhance absorption.\n\nComplete the full course even if symptoms improve early.\n\nDo not double the dose if a dose is missed—take it as soon as remembered unless it is nearly time for the next dose.\n\nSide Effects\nLike all medicines, CEPHODOXIAA 200 may cause mild to moderate side effects. Common ones include:\n\nGastrointestinal upset (nausea, diarrhea, abdominal pain)\n\nHeadache or dizziness\n\nSkin rash or itching\n\nRare but serious side effects:\n\nSevere allergic reactions (swelling, difficulty breathing)\n\nPseudomembranous colitis (persistent diarrhea)\n\nLiver enzyme elevations\n\nDrug Interactions\nAntacids & H2 blockers: May reduce absorption of Cefpodoxime. Take at least 2–3 hours apart.\n\nBlood thinners (e.g., warfarin): May increase risk of bleeding.\n\nOther antibiotics: Avoid concurrent use unless directed by a doctor to prevent resistance.\n\nAlways inform your physician of all medications and supplements you are taking before starting therapy.\n\nConclusion\nCEPHODOXIAA 200 (Cefpodoxime Proxetil 200 mg) from Steris Healthcare Pvt. Ltd. is a reliable, broad-spectrum antibiotic used in the management of common bacterial infections. With its excellent safety profile, ease of oral administration, and clinical efficacy, it remains a preferred choice for doctors worldwide. Patients should adhere strictly to prescribed dosage and complete the treatment course to ensure optimal results and prevent antibiotic resistance.", "price": 173.0, "discountamount": 52.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2173, "imageuri": "https://productimages.withfloats.com/actual/69294e18b456de02c99ff75f.png", "tileimageuri": "https://productimages.withfloats.com/tile/69294e18b456de02c99ff75f.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-09-06T12:02:48.098Z", "updatedon": "2025-12-09T06:14:09.48Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/cefpodoxime-proxetil-tablets-ip-200-mg/2173", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CEPHODOXIAA 200", "category": "GENERAL RANGE", "tags": [ "Cefpodoxime Proxetil 200 mg", "bacterial infections", "Broad-spectrum antibacterial activity", "CEPHODOXIAA 200", "urinary tract infections" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "685d3aee734cdee72771a953", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "rifaximin 200", "description": "RIFAXEMANIA 200 is a targeted intestinal antibiotic that contains Rifaximin 200 mg. This medication is widely used to treat gastrointestinal infections without affecting the rest of the body. Because of its poor absorption into the bloodstream, it works directly in the digestive tract, helping to treat infections like traveler’s diarrhea, IBS-D (Irritable Bowel Syndrome with Diarrhea), and complications related to liver conditions such as hepatic encephalopathy. RIFAXEMANIA 200 is formulated in tablet form, offering convenience, precision, and effective relief.\n\nWhat is Rifaximin 200 mg?\nRifaximin 200 mg is a non-systemic, semi-synthetic antibiotic derived from the rifamycin group. It functions by binding to bacterial RNA polymerase, preventing bacteria from multiplying. Since it stays confined to the gastrointestinal tract and is not absorbed significantly into the bloodstream, it’s ideal for treating localized gut infections.\n\nThis unique property makes the rifaximin 200 tablet suitable for conditions that do not require full-body antibiotic exposure, ensuring effective treatment with minimal side effects.\n\nUses of Rifaximin 200 Tablet\nRifaximin 200 mg is prescribed in tablet form to treat a variety of gut-related conditions. Common uses include the treatment of traveler’s diarrhea caused by non-invasive strains of E. coli, reducing the recurrence of hepatic encephalopathy in individuals with chronic liver disease, and relieving symptoms associated with IBS-D such as diarrhea, bloating, and abdominal pain.\n\nAdditionally, rifaximin is sometimes used to manage small intestinal bacterial overgrowth (SIBO), functional digestive disorders, and as part of combination therapy in certain inflammatory bowel conditions. These rifaximin 200 mg uses make it a valuable option for both acute and chronic digestive health management.\n\nSide Effects of Rifaximin 200 mg\nRifaximin is generally considered safe and well-tolerated due to its low systemic absorption. However, like all medications, some individuals may experience side effects. These can include nausea, abdominal pain, bloating, headache, constipation, or mild diarrhea. In rare cases, allergic skin reactions or fatigue may occur.\n\nMost of these effects are mild and temporary. If symptoms persist or worsen, it is advisable to contact a healthcare professional for further evaluation.\n\nPrecautions Before Using RIFAXEMANIA 200\nBefore using RIFAXEMANIA 200, patients should consider a few important precautions. Anyone with a known allergy to rifaximin or related antibiotics in the rifamycin class should avoid this medication. It should also be used cautiously in people with moderate to severe liver disease, as systemic absorption may be higher in such cases.\n\nPregnant or breastfeeding individuals should only use this product after consulting a physician. Rifaximin 200 mg is not recommended in cases of bloody diarrhea or fever, where a more systemic antibiotic may be required. Proper diagnosis and physician supervision are essential before starting treatment.\n\nDrug Interactions with Rifaximin 200 mg\nAlthough rifaximin is minimally absorbed into the bloodstream, it may still interact with certain medications, particularly in patients with liver impairment. For example, cyclosporine can significantly raise blood levels of rifaximin, requiring dose adjustments.\n\nOther drugs that may interact include warfarin (where INR monitoring is necessary), oral contraceptives (as effectiveness may decrease), and antiepileptic medications (which may have altered therapeutic effects). Always inform your doctor about all current medications, including over-the-counter supplements and herbal products, before starting rifaximin 200 tablet.\n\nWhy RIFAXEMANIA 200 is Recommended\nRIFAXEMANIA 200 offers precise and localized antibacterial action in the intestines without exposing the rest of the body to unnecessary drug effects. This makes it a preferred option for managing conditions like traveler’s diarrhea, hepatic encephalopathy, and IBS-D. Its convenient tablet form, reliable safety profile, and effectiveness in reducing symptoms make it a valuable part of modern gastrointestinal therapy.\n\nConclusion\nRIFAXEMANIA 200, containing Rifaximin 200 mg, is a clinically effective and safe treatment for bacterial infections limited to the gastrointestinal tract. With minimal absorption and a strong local antibacterial effect, it helps address common and chronic digestive conditions while minimizing adverse effects. Whether you are managing liver-related complications or looking for relief from persistent diarrhea and gut discomfort, RIFAXEMANIA 200 delivers dependable results.\n\nAlways follow your healthcare provider’s instructions for dosage and duration to ensure the best possible outcomes.\n\n", "price": 149.0, "discountamount": 45.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": [ "rifaxemania 200", "rifaxemania 200 patients", "breastfeeding individuals", "valuable part", "current medications", "antiepileptic medications", "cases pregnant", "mild diarrhea", "effective relief", "rifaxemania 200rifaxemania 200", "rifaximin 200 mg", "persistent diarrhea", "safe treatment", "clinically effective", "preferred option", "herbal products", "overthecounter supplements", "oral contraceptives", "inr monitoring", "minimally absorbed", "physician supervision", "bloody diarrhea", "rifamycin class", "related antibiotics", "important precautions", "evaluation precautions", "welltolerated due", "valuable option", "combination therapy", "diarrhea bloating", "hepatic encephalopathy", "noninvasive strains", "tablet form", "absorbed significantly", "stays confined", "rifamycin group", "works directly", "poor absorption", "symptoms persist", "relieving symptoms", "liver impairment", "healthcare professional", "coli reducing", "complications related", "systemic absorption", "treat infections", "gastrointestinal tract", "minimal absorption", "managing conditions", "systemic antibiotic", "liver conditions", "reducing symptoms make", "treat gastrointestinal infections", "low systemic absorption", "managing liverrelated complications", "travelers diarrhea caused", "unique property makes", "minimal side effects", "chronic digestive conditions", "inflammatory bowel conditions", "gutrelated conditions common", "digestive tract helping", "healthcare providers instructions", "severe liver disease", "generally considered safe", "chronic liver disease", "targeted intestinal antibiotic", "minimizing adverse effects", "bacterial infections limited", "unnecessary drug effects", "altered therapeutic effects", "experience side effects", "helps address common", "localized antibacterial action", "required proper diagnosis" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2138, "imageuri": "https://productimages.withfloats.com/actual/685d3af25609b7ccc73e989b.png", "tileimageuri": "https://productimages.withfloats.com/tile/685d3af25609b7ccc73e989b.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-06-26T12:19:58.961Z", "updatedon": "2025-12-08T09:03:06.758Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/rifaximin-200/2138", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "RIFAXEMANIA 200", "category": "GASTROLOGYRANGE", "tags": [ "rifaximin 200", "rifaximin 200 mg uses in hindi", "rifaximin 200 mg uses" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "666c15c3d89239081848a6ac", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "ZIPRANODE 40 ", "description": "ZIPRANODE 40 \nZiprasidone Capsules (40mg)\nIntroduction:\n\nZIPRANODE 40 contains Ziprasidone, an atypical antipsychotic medication, at a dosage strength of 40mg. It is designed for the treatment of schizophrenia and the manic or mixed episodes associated with bipolar disorder. ZIPRANODE 40 works by modulating the activity of neurotransmitters in the brain, helping to stabilize mood and reduce psychotic symptoms.\nKey Features and Benefits:\n\nAntipsychotic Action:\n\nZIPRANODE 40 is effective in treating the symptoms of schizophrenia, including hallucinations, delusions, thought disorders, and social withdrawal. It helps restore balance to neurotransmitters in the brain, particularly dopamine and serotonin.\nMood Stabilization:\n\nZiprasidone is also used to manage manic or mixed episodes in bipolar disorder. It helps control mood swings, reducing the intensity and frequency of manic episodes and helping patients maintain a stable mood.\nDual Mechanism of Action:\n\nZIPRANODE 40 acts as both a serotonin and dopamine receptor antagonist. This dual mechanism of action helps in effectively managing a broad range of symptoms associated with schizophrenia and bipolar disorder.\nFavorable Side Effect Profile:\n\nCompared to other antipsychotics, Ziprasidone has a lower risk of causing weight gain and metabolic disturbances, making it a preferred option for long-term management of psychiatric conditions.\nDosage and Administration:\n\nInitial Dosage for Schizophrenia:\n\nThe recommended starting dose of ZIPRANODE 40 for adults with schizophrenia is 20mg twice daily. The dose can be increased gradually based on the patient’s response and tolerability, up to a maximum of 80mg twice daily.\nInitial Dosage for Bipolar Disorder:\n\nFor the treatment of manic or mixed episodes in bipolar disorder, the initial dose is 40mg twice daily. The dose can be adjusted based on clinical response, with a usual range of 40-80mg twice daily.\nAdministration Instructions:\n\nZIPRANODE 40 capsules should be taken orally with food to enhance absorption. Swallow the capsules whole with water. Do not crush or chew the capsules.\nContinued Monitoring:\n\nRegular monitoring of symptoms, side effects, and overall health is essential during ZIPRANODE 40 therapy to ensure therapeutic efficacy and patient safety.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order NOW\nhttps://www.sterisonline.com/product/zipranode-40-133982", "price": 173.0, "discountamount": 51.9, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "80mg", "40mg", "food", "EMAIL", "water", "brain", "adults", "balance", "maximum", "activity", "patients", "Benefits", "serotonin", "intensity", "delusions", "treatment", "frequency", "absorption", "lower risk", "stable mood", "usual range", "broad range", "information", "weight gain", "mood swings", "initial dose", "sterisonline", "tolerability", "Key Features", "side effects", "sterispharma", "Introduction", "starting dose", "schizophrenia", "CALL/WHATSAPP", "hallucinations", "patient safety", "manic episodes", "overall health", "mixed episodes", "Dual Mechanism", "Initial Dosage", "dosage strength", "bipolar disorder", "thought disorders", "social withdrawal", "clinical response", "ZIPRANODE 40 acts", "neurotransmitters", "Mood Stabilization", "psychotic symptoms", "Regular monitoring", "Antipsychotic Action", "therapeutic efficacy", "ZIPRANODE 40 therapy", "Continued Monitoring", "long-term management", "Ziprasidone Capsules", "other antipsychotics", "ZIPRANODE 40 capsules", "psychiatric conditions", "metabolic disturbances", "Administration Instructions", "dopamine receptor antagonist", "Favorable Side Effect Profile", "atypical antipsychotic medication" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1913, "imageuri": "https://productimages.withfloats.com/actual/667d1364c134db5b38ba45ba.png", "tileimageuri": "https://productimages.withfloats.com/tile/667d1364c134db5b38ba45ba.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-14T10:04:51.679Z", "updatedon": "2025-12-17T06:00:36.304Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/zipranode-40-/1913", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "ZIPRANODE 40 ", "category": "NEUROLOGY RANGE", "tags": [ "Ziprasidone Capsules (40mg)", "ZIPRANODE 40", "", "ziprasidone side effects", "ziprasidone warnings", "ziprasidone side effects weight loss", "ziprasidone mechanism of action" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6661a73687f0960e14a2c739", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "mycophenolate sodium 360 mg", "description": "MYCOPLASM S 360 \nMycophenolate sodium 360 mg is an essential immunosuppressant medication designed to prevent organ transplant rejection, particularly for kidney, heart, and liver transplants. As the sodium salt of mycophenolic acid, it delivers 360 mg of the active moiety per tablet, providing targeted immune suppression to help patients maintain their new organs long-term. This product stands out for its enteric-coated formulation, which enhances gastrointestinal tolerability compared to other forms, making it a preferred choice in post-transplant care regimens.​\n\nUses of Mycophenolate Sodium 360 mg\nMycophenolate sodium 360 mg primarily serves as a prophylactic agent against acute rejection in adult and pediatric patients receiving allogeneic renal, cardiac, or hepatic transplants. It works alongside other immunosuppressants like cyclosporine and corticosteroids to create a balanced regimen that minimizes the risk of graft loss. Clinically, it proves effective in de novo transplant recipients, where starting therapy early post-surgery significantly reduces rejection episodes. Beyond transplants, off-label applications include managing refractory autoimmune conditions such as lupus nephritis or myasthenia gravis, where immune overactivity damages tissues.​\n\nThe drug targets the proliferation of T- and B-lymphocytes, key players in immune responses that can attack transplanted organs. In renal transplant patients, for instance, it helps preserve kidney function by curbing antibody-mediated rejection. Its role extends to maintenance therapy, where consistent dosing sustains immunosuppression without excessive toxicity. Healthcare providers often adjust it based on patient response and trough levels of the active metabolite, mycophenolic acid (MPA), ensuring optimal therapeutic outcomes.​\n\nKey Benefits of Mycophenolate Sodium 360 mg\nMycophenolate sodium 360 mg offers several advantages that make it a cornerstone in transplant medicine. One primary benefit is its selective inhibition of lymphocyte proliferation, sparing other cell types and reducing broad-spectrum immunosuppression risks. This leads to fewer opportunistic infections compared to older agents like azathioprine. The enteric coating minimizes upper GI upset, improving patient compliance—studies show higher adherence rates with this formulation.​\n\nEnhanced Graft Survival: Prolongs organ viability by effectively suppressing cell-mediated and humoral immunity, with clinical data showing reduced biopsy-proven rejection rates.\n\nImproved Tolerability: Lower incidence of nausea and diarrhea due to delayed-release technology, allowing twice-daily dosing without food restrictions.\n\nFlexible Dosing: Equivalent to 720 mg mycophenolate mofetil, but with predictable MPA exposure via enterohepatic recirculation for steady-state efficacy.\n\nPediatric Suitability: Approved for children over 2 years in renal transplants, supporting growth without compromising safety.\n\nCost-Effective Long-Term Option: Balances efficacy and side effect profile, potentially lowering overall healthcare costs from fewer rejections or hospitalizations.​\n\nPatients experience better quality of life, with sustained energy levels and fewer interruptions from acute rejection crises. Its metabolism to MPA via liver glucuronidation ensures reliable pharmacokinetics, even in patients with mild renal impairment.​\n\nSide Effects of Mycophenolate Sodium 360 mg\nWhile highly effective, mycophenolate sodium 360 mg carries risks typical of immunosuppressants, necessitating vigilant monitoring. Common adverse effects stem from its impact on rapidly dividing cells, particularly in the gut and bone marrow.\n\nCommon Side Effects\nGastrointestinal issues like diarrhea, nausea, vomiting, and abdominal pain, affecting up to 30-50% of users.\n\nHeadache, insomnia, and tremor, often mild and transient.\n\nInfections such as urinary tract or respiratory, due to moderated immunity.\n\nHypertension or peripheral edema, manageable with supportive care.\n\nLeukopenia or anemia, requiring periodic blood counts.​\n\nSerious Side Effects\nSevere myelosuppression leading to neutropenia or thrombocytopenia, which can increase infection or bleeding risks.\n\nProgressive multifocal leukoencephalopathy (PML), a rare brain infection linked to JC virus reactivation.\n\nGastrointestinal perforation or bleeding, especially in at-risk patients.\n\nIncreased malignancy risk, including lymphoma or skin cancers, over long-term use.\n\nHypersensitivity reactions like rash or anaphylaxis.​\n\nRegular complete blood counts, viral monitoring (e.g., CMV, BK virus), and skin exams mitigate these risks. Dose reductions or discontinuation may be needed if counts drop significantly.​\n\nMechanism of Action\nMycophenolate sodium 360 mg rapidly hydrolyzes to mycophenolic acid (MPA), a potent, reversible, non-competitive inhibitor of inosine-5'-monophosphate dehydrogenase (IMPDH). This enzyme catalyzes the rate-limiting step in de novo guanine nucleotide synthesis, depleting guanosine nucleotides essential for T- and B-cell DNA replication. Lymphocytes, reliant on this pathway, undergo proliferation arrest, suppressing both cell-mediated immunity and antibody production.​\n\nMPA also hinders glycosylation of adhesion molecules on lymphocytes and monocytes, impeding their migration to graft sites. It reduces nitric oxide production in macrophages without affecting endothelial cells, curbing inflammation. Enterohepatic recirculation of the glucuronide metabolite (MPAG) prolongs MPA exposure, enhancing efficacy. Protein binding to albumin (around 97%) ensures targeted delivery, with clearance primarily renal for the inactive form.​\n\nDosage and Administration Guidelines\nStandard dosing for renal transplant is 720 mg (two 360 mg tablets) twice daily, starting within 72 hours post-surgery. Adjustments occur for hepatic or cardiac transplants, often alongside cyclosporine. Therapeutic drug monitoring of MPA AUC (area under curve) optimizes levels between 30-60 mcg·h/mL. Take on an empty stomach for best absorption, though food has minimal impact due to the coating.​\n\nPrecautions and Warnings\nAvoid in pregnancy (Category D) due to teratogenicity—use contraception and regular pregnancy tests. Contraindicated in active untreated infections. Monitor for GI bleeding in ulcerative colitis patients. Drug interactions with antacids, cholestyramine, or rifampin alter MPA levels. Live vaccines are prohibited.​\n\nConclusion\nMycophenolate sodium 360 mg represents a vital advancement in transplant immunosuppression, offering robust protection against rejection with a favorable benefit-risk profile. Its targeted action on lymphocytes, combined with improved GI tolerance, empowers patients to thrive post-transplant. By integrating it into comprehensive regimens with close monitoring, healthcare teams maximize graft success and patient well-being. Always consult a specialist for personalized guidance to harness its full potential safely.\nEmail: info@sterispharma.com / contact@sterispharma.com\nCall/WhatsApp: 7877551268, 7849827488\nORDER Now: \nhttps://www.sterisonline.com/product/mycoplasm-s-360-133670\n\n\n\n\n\n\n", "price": 767.0, "discountamount": 567.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "dose", "risk", "body", "part", "ORDER", "360mg", "Email", "cells", "dosage", "nausea", "vomiting", "schedule", "headache", "strength", "WhatsApp", "diarrhea", "activity", "rejection", "treatment", "infections", "supplements", "information", "MYCOPLASM S", "sterispharma", "sterisonline", "stomach pain", "blood counts", "immune system", "complications", "liver problems", "liver function", "other medications", "Regular monitoring", "medical conditions", "healthcare provider", "Common side effects", "Serious side effects", "white blood cell count", "potential drug interactions", "optimal therapeutic effects", "combination therapy regimen", "organ transplant recipients", "Mycophenolate Sodium therapy", "other immunosuppressive drugs" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1474, "imageuri": "https://productimages.withfloats.com/actual/6661a739c749b7962dbc08c6.jpg", "tileimageuri": "https://productimages.withfloats.com/tile/6661a739c749b7962dbc08c6.jpg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-06T12:10:30.488Z", "updatedon": "2025-12-04T07:44:09.122Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/mycophenolate-sodium-360-mg/1474", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MYCOPLASM S 360 ", "category": "Oncology", "tags": [ "MYCOPLASM S 360", "Mycophenolate sodium (360mg)", "Mycophenolate sodium 360 mg price", "Mycophenolate sodium 360 mg brands", "Mycophenolate sodium 360 mg side effects", "Myfortic 360 alternative", "Myfortic 500" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "666193e1db100e1fdc2dbb78", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "PRULITECH 600", "description": "PRULITECH 600 is a next-generation oral antibiotic formulated with Prulifloxacin (600mg), designed to combat a wide spectrum of bacterial infections efficiently. As a fluoroquinolone prodrug, Prulifloxacin ensures rapid conversion into its active form, delivering potent antibacterial action at the site of infection. Ideal for respiratory tract infections, urinary tract infections, and certain gastrointestinal infections, PRULITECH 600 is trusted for both its efficacy and patient convenience.\n\nKey Ingredient\nPrulifloxacin (600mg): A fluoroquinolone-class antibiotic that acts as a prodrug and is converted into Ulifloxacin after administration. This active metabolite offers strong tissue penetration and enhanced antibacterial activity.\n\nKey Benefits\nBroad-Spectrum Coverage: Effective against both Gram-positive and Gram-negative bacteria.\n\nFast-Acting Relief: Begins working quickly to reduce infection-related symptoms.\n\nOnce-Daily Dosage: Improves patient compliance and simplifies treatment regimens.\n\nWell-Absorbed Formulation: Offers high bioavailability and systemic distribution.\n\nSuitable for Various Infections: Effective for infections of the lungs, bladder, urinary tract, and digestive system.\n\nHow Does It Work?\nPrulifloxacin works by targeting and inhibiting bacterial enzymes DNA gyrase and topoisomerase IV, which are essential for bacterial DNA replication, repair, and transcription. Once ingested, it is metabolized into Ulifloxacin, which binds to these enzymes, effectively halting bacterial growth and eliminating the infection from within.\n\nDirections for Use\nTake one tablet of PRULITECH 600 once daily or as prescribed by your physician.\n\nSwallow the tablet whole with a full glass of water.\n\nIt can be taken with or without food but should not be consumed alongside dairy products, antacids, or iron supplements within 2 hours of use.\n\nComplete the full course of therapy even if symptoms subside early.\n\nSide Effects\nThough well-tolerated, PRULITECH 600 may cause mild side effects in some individuals, such as:\n\nNausea or gastrointestinal discomfort\n\nHeadache or dizziness\n\nMild rash or skin sensitivity to sunlight\n\nRarely, tendon discomfort or allergic reactions\n\nSeek medical advice if severe or persistent symptoms occur.\n\nConclusion\nPRULITECH 600, powered by Prulifloxacin 600mg, is a reliable and modern solution for treating complex bacterial infections with precision and speed. Its high tissue penetration, broad-spectrum activity, and patient-friendly dosage make it a preferred choice among healthcare professionals. For safe and effective results, always use under the guidance of a registered medical practitioner.", "price": 439.0, "discountamount": 132.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "skin", "Call", "risk", "ORDER", "Email", "brand", "Price", "600mg", "doctor", "nausea", "spread", "growth", "alcohol", "enzymes", "Purpose", "product", "WhatsApp", "headache", "diarrhea", "location", "allergies", "dizziness", "Conclusion", "one tablet", "medication", "Precautions", "instructions", "sterispharma", "sterisonline", "Prulifloxacin", "PRULIFLOX 600", "abdominal pain", "standard dosage", "optimal results", "local pharmacies", "concise overview", "active ingredient", "medical conditions", "Common side effects", "healthcare provider", "effective antibiotic", "soft tissue infections", "urinary tract infections", "broad-spectrum antibiotic", "bacterial DNA replication", "Serious allergic reactions", "gastrointestinal infections", "specific pricing information", "various bacterial infections", "respiratory tract infections" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1455, "imageuri": "https://productimages.withfloats.com/actual/6831a100b66d3990c342eee6.png", "tileimageuri": "https://productimages.withfloats.com/tile/6831a100b66d3990c342eee6.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-06T10:48:01.222Z", "updatedon": "2025-05-24T10:35:42.945Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/prulitech-600/1455", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "PRULITECH 600", "category": "GENERAL RANGE", "tags": [ "Prulifloxacin (600mg)", "Prulifloxacin 600 mg Uses in Hindi", "Prulifloxacin 600 mg dose", "Prulifloxacin 600 mg side effects", "Prulifloxacin vs levofloxacin" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6943af86161ad9de85f42b10", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Imatinib IP 400mg", "description": "IMATIFLOW 400, containing Imatinib IP 400mg, represents a breakthrough in targeted cancer therapy, offering patients a precise weapon against specific malignancies. This oral medication belongs to the class of tyrosine kinase inhibitors, revolutionizing treatment for conditions once deemed challenging to manage. By blocking abnormal proteins that fuel cancer cell growth, IMATIFLOW 400 helps restore normal cellular function and improves quality of life for many users.​\n\nProduct Overview\nIMATIFLOW 400 is a branded formulation of Imatinib mesylate 400mg, produced to high pharmaceutical standards for consistent efficacy and bioavailability. Each tablet delivers the active ingredient in a film-coated form, designed for once-daily administration with food to enhance absorption and minimize gastrointestinal upset. Developed for adult patients, it targets cancers driven by dysregulated tyrosine kinases like BCR-ABL, c-KIT, and PDGFR, making it a cornerstone in modern oncology protocols.​\n\nThe medication's mechanism hinges on competitive inhibition at the ATP-binding site of these kinases, halting downstream signaling pathways that promote uncontrolled proliferation, survival, and metastasis of malignant cells. Unlike traditional chemotherapy, which broadly attacks dividing cells, IMATIFLOW 400 spares most healthy tissues, leading to a more favorable safety profile. Clinical data from pivotal trials underscore its role as first-line therapy, with high response rates observed within months of initiation.​\n\nPrimary Uses\nIMATIFLOW 400 excels in treating chronic myeloid leukemia (CML), particularly in the chronic phase where it induces deep molecular responses in over 80% of patients. It suppresses the Philadelphia chromosome-positive cells hallmark of CML by inhibiting the BCR-ABL fusion protein, dramatically extending progression-free survival. For newly diagnosed patients, standard dosing starts at 400mg daily, often achieving complete cytogenetic remission.​\n\nIn gastrointestinal stromal tumors (GIST), IMATIFLOW 400 targets KIT or PDGFRA mutations, shrinking unresectable tumors and delaying progression in advanced cases. The recommended dose remains 400mg once daily, with potential escalation to 600-800mg for resistant strains, as per oncology guidelines. It also finds application in dermatofibrosarcoma protuberans (DFSP), aggressive systemic mastocytosis, and certain myelodysplastic syndromes, broadening its utility in precision medicine.​\n\nHealthcare providers monitor response via PCR for BCR-ABL transcripts in CML or imaging for GIST, adjusting therapy based on milestones like major molecular response. Patients with Ph+ acute lymphoblastic leukemia (ALL) may receive it adjunctively, enhancing outcomes when combined with chemotherapy. Overall, IMATIFLOW 400 transforms these diseases from fatal to chronically manageable.​\n\nKey Benefits\nOne standout benefit of IMATIFLOW 400 is its oral convenience, eliminating the need for frequent hospital visits associated with infusions. Response rates exceed 90% in early CML, with many patients achieving treatment-free remission after sustained deep responses, a paradigm shift from interferon-era therapies.​\n\nTumor control in GIST prevents life-threatening complications like bowel obstruction, improving survival from months to years. Its specificity reduces severe toxicities, allowing patients to maintain daily activities, work, and social engagements with minimal disruption. Long-term studies report 10-year survival rates above 80% in CML, underscoring durable efficacy.​\n\nAdditional advantages include cost-effectiveness over biologics and compatibility with supportive care like hydroxyurea for cytoreduction. Fluid retention, while common, responds well to diuretics, preserving cardiac function. For Indian patients, accessible pricing via brands like IMATIFLOW 400 supports equitable care in resource-limited settings.​\n\nPotential Side Effects\nWhile generally well-tolerated, IMATIFLOW 400 can cause edema (swelling in legs or face) in up to 70% of users, managed by dose reduction or supportive measures. Gastrointestinal issues like nausea, vomiting, and diarrhea affect 40-50%, often resolving with antiemetics and dietary adjustments.​\n\nMusculoskeletal pain, cramps, and fatigue occur frequently, alongside rash and abdominal discomfort. Hematologic effects include neutropenia or thrombocytopenia, necessitating regular blood counts. Rare but serious risks involve liver enzyme elevation, heart failure, or hemorrhage; prompt reporting of symptoms like shortness of breath or yellowing skin is crucial.​\n\nAvoid grapefruit juice, as it elevates drug levels, and inform doctors of concurrent medications like CYP3A4 inhibitors. Pregnancy category D status advises contraception, with monitoring for growth retardation in exposed fetuses. Dizziness may impair driving, so caution is essential during initial weeks.​\n\nDosage and Administration Guidelines\nSwallow IMATIFLOW 400 whole with a meal and full glass of water to optimize pharmacokinetics and reduce esophageal irritation. The standard adult dose for CML chronic phase is 400mg daily; for accelerated phase or blast crisis, 600mg. GIST dosing mirrors 400mg, titrated based on tolerance and response.​\n\nRenal or hepatic impairment requires dose adjustments—reduce to 300-400mg in moderate cases. Do not crush or chew tablets. Missed doses should be taken promptly unless near the next, avoiding doubles. Long-term use demands quarterly monitoring of CBC, liver function, and ECG.​\n\nPrecautions and Interactions\nPatients with a cardiac history need baseline echocardiograms, as QT prolongation or effusion risks exist. Drug interactions abound: St. John's wort induces metabolism, reducing efficacy; ketoconazole boosts levels. Vaccines, especially live ones, are contraindicated during therapy.​\n\nRegular dermatologic checks mitigate skin cancer risk from prolonged use. Hydration combats fluid retention, and low-salt diets aid management. Steris Healthcare emphasizes patient education via counseling on adherence for optimal outcomes.​\n\nConclusion\nIMATIFLOW 400 (Imatinib IP 400mg) stands as a testament to targeted therapy's power, offering robust control over CML, GIST, and related cancers with a balance of efficacy and manageability. Its benefits in prolonging life and enhancing daily functioning far outweigh transient side effects for most when monitored diligently. Consult oncologists for personalized plans, ensuring this innovative treatment maximizes hope and health in the fight against cancer.", "price": 1827.0, "discountamount": 540.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2249, "imageuri": "https://productimages.withfloats.com/actual/6943b026ca1b0dcfc6c37820.png", "tileimageuri": "https://productimages.withfloats.com/tile/6943b026ca1b0dcfc6c37820.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-18T07:38:46.766Z", "updatedon": "2025-12-18T07:41:25.851Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/imatinib-ip-400mg/2249", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "IMATIFLOW 400", "category": "NEPHROLOGYRANGE", "tags": [ "Imatinib IP 400mg", "offering robust control over CML.", "related cancers with a balance of efficacy and manageability.", "innovative treatment maximizes hope and health in the fight against cancer.", "cancer therapy.", "fuel cancer cell growth.", "chemotherapy." ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "694004d8504825bb23fa3c1f", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Terbinafine and Itraconazole Tablets 250/100 mg", "description": "CONARIS T100 is a potent antifungal medication formulated with Terbinafine 250 mg and Itraconazole 100 mg. This combination tablet is designed to treat a wide range of fungal infections affecting the skin, nails, and other body parts. Terbinafine and Itraconazole work synergistically to eliminate fungi effectively by targeting their cell membranes and inhibiting growth, providing faster relief from symptoms such as itching, redness, scaling, and discomfort.\n\nFungal infections are common in humid climates and among individuals with compromised immunity, and medications like CONARIS T100 are essential for managing stubborn and recurrent infections. This combination therapy is often prescribed by dermatologists and healthcare professionals for moderate to severe fungal conditions.\n\nUses\n\nCONARIS T100 is used in the treatment of several fungal infections, including:\n\nDermatophytosis (Ringworm): Effective against infections of the skin, hair, and nails caused by dermatophytes.\n\nOnychomycosis (Nail Fungus): Helps in treating fungal infections of fingernails and toenails.\n\nTinea Infections: Treats tinea corporis, tinea cruris, and tinea pedis (athlete’s foot).\n\nCandidiasis: Useful in managing Candida infections affecting the skin and mucous membranes.\n\nRecurrent or Resistant Fungal Infections: Provides stronger antifungal action in cases not responsive to monotherapy.\n\nBenefits\n1. Broad-Spectrum Antifungal Action\n\nThe combination of Terbinafine and Itraconazole ensures effective activity against a wide variety of fungal species, including dermatophytes and yeasts.\n\n2. Faster Symptom Relief\n\nBy targeting fungi at multiple levels, CONARIS T100 helps relieve itching, redness, scaling, and discomfort more quickly than single-agent therapy.\n\n3. Treats Nail and Skin Infections\n\nTerbinafine penetrates nails effectively, while Itraconazole enhances the antifungal spectrum, making the combination ideal for nail and skin fungal infections.\n\n4. Reduces Recurrence\n\nCombination therapy decreases the risk of fungal infections returning by ensuring complete eradication of the pathogen.\n\n5. Convenient Dosage Form\n\nAvailable as an oral tablet, making it easy to administer and suitable for long-term treatment if prescribed.\n\nDosage\n\nAdults: Usually, one tablet of CONARIS T100 daily, preferably after meals, or as directed by a healthcare professional.\n\nTreatment Duration: Varies depending on the type and severity of infection; may range from 2 to 12 weeks for skin infections and longer for nail infections.\n\nImportant: Do not self-adjust dosage or stop treatment prematurely, as incomplete therapy can lead to recurrence or resistance.\n\nSide Effects\n\nCONARIS T100 is generally well tolerated when used as prescribed. Mild side effects may include:\n\nNausea or vomiting\n\nStomach upset or diarrhea\n\nHeadache\n\nDizziness\n\nSerious Side Effects (Rare)\n\nLiver enzyme elevation (monitoring recommended for long-term use)\n\nAllergic reactions such as rash, itching, or swelling\n\nSevere gastrointestinal discomfort\n\nConsult a healthcare provider immediately if you experience jaundice, persistent fatigue, or severe allergic reactions.\n\nPrecautions and Warning\n\nPregnancy and Breastfeeding: Use only if prescribed by a doctor; safety during pregnancy is not fully established.\n\nLiver or Kidney Disorders: Dose adjustment or close monitoring may be required.\n\nDrug Interactions: Inform your doctor about all medications, especially antifungals, statins, or anticoagulants.\n\nAvoid Self-Medication: Fungal infections may mimic other skin conditions, so proper diagnosis is essential.\n\nAlcohol Consumption: Avoid alcohol as it may increase liver toxicity risk.\n\nStorage: Store in a cool, dry place away from direct sunlight and out of children’s reach.\n\nConclusion\n\nCONARIS T100, containing Terbinafine 250 mg and Itraconazole 100 mg, is a reliable and effective treatment for a wide spectrum of fungal infections, including skin, nail, and mucosal infections. Its dual-action antifungal mechanism provides faster symptom relief, reduces recurrence, and improves overall patient outcomes.\n\nWhen used under medical supervision and following prescribed dosage, CONARIS T100 offers a safe and convenient option for managing both common and stubborn fungal infections, ensuring better skin and nail health and enhanced quality of life.", "price": 184.0, "discountamount": 55.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2248, "imageuri": "https://productimages.withfloats.com/actual/694004da351fe1d6b98476e6.png", "tileimageuri": "https://productimages.withfloats.com/tile/694004da351fe1d6b98476e6.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-15T12:53:44.573Z", "updatedon": "2025-12-16T05:44:32.639Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/terbinafine-and-itraconazole-tablets-250-100-mg/2248", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CONARIS T100", "category": "DERMATALOGY", "tags": [ "terbinafine and itraconazole tablets", "terbinafine and itraconazole together", "terbinafine and itraconazole tablets uses", "terbinafine and itraconazole for nail fungus" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false } ], "hasmoreitems": false, "isapirequest": false, "totalresults": 27, "query": null, "floatingpoint": null }