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"description": "DIOWELPREX 250 ORAL SOLUTION \nDivalproex (250mg/5ml)\nIntroduction\nDIOWELPREX 250 ORAL SOLUTION contains Divalproex (250mg/5ml), an anticonvulsant and mood-stabilizing medication used to treat various neurological and psychiatric conditions. It is particularly effective in managing epilepsy, bipolar disorder, and preventing migraine headaches.\n\nComposition\n\nDivalproex Sodium (250mg/5ml): A stable coordination compound comprised of sodium valproate and valproic acid in a 1:1 molar relationship, providing a source of valproate ion which exhibits anticonvulsant and mood-stabilizing properties.\nMechanism of Action\nDivalproex works by increasing the levels of gamma-aminobutyric acid (GABA) in the brain, an inhibitory neurotransmitter that helps calm neuronal activity. It stabilizes electrical activity in the brain, reducing the frequency and severity of seizures, stabilizing mood in bipolar disorder, and preventing migraine headaches by altering the way nerves send signals.\n\nIndications\nDIOWELPREX 250 ORAL SOLUTION is indicated for:\n\nEpilepsy: Used to control various types of seizures including complex partial seizures and simple and complex absence seizures.\nBipolar Disorder: Helps in the management of manic episodes associated with bipolar disorder.\nMigraine Prophylaxis: Used to prevent migraine headaches.\nDosage and Administration\n\nEpilepsy: The initial dose is typically 10-15 mg/kg/day, gradually increased as needed and tolerated to achieve optimal clinical response.\nBipolar Disorder: The initial dose is generally 750 mg/day, given in divided doses, adjusted according to clinical response.\nMigraine Prophylaxis: The initial dose is usually 250 mg twice daily, adjusted as necessary.\nIt is essential to follow the prescribed dosage and administration instructions provided by a healthcare professional. The oral solution should be measured accurately using a dosing syringe or cup to ensure the correct dose is administered.\nSide Effects\nCommon side effects may include:\n\nNausea\nDrowsiness\nDizziness\nTremor\nHair loss\nWeight gain\nGastrointestinal disturbances\nMore severe side effects can include:\n\nLiver damage\nPancreatitis\nThrombocytopenia (low platelet count)\nHyperammonemia (high levels of ammonia in the blood)\nPrecautions\n\nLiver Function: Regular monitoring of liver function tests is recommended due to the risk of hepatotoxicity.\nPancreatitis: Patients should be monitored for signs of pancreatitis.\nPregnancy: Divalproex is associated with an increased risk of congenital malformations and should be used during pregnancy only if absolutely necessary and prescribed by a healthcare provider.\nBleeding Disorders: Caution is advised in patients with known bleeding disorders due to the risk of thrombocytopenia.\nDrug Interactions\n\nAntiepileptic Drugs: Concurrent use with other antiepileptic drugs may require dosage adjustments.\nWarfarin: May enhance the anticoagulant effect, necessitating close monitoring of INR levels.\nTopiramate: Co-administration can lead to hyperammonemia and encephalopathy.\nAlcohol: Should be avoided as it can exacerbate the side effects of Divalproex and further impair mental and motor skills.\nConclusion\nDIOWELPREX 250 ORAL SOLUTION is an effective medication for managing epilepsy, bipolar disorder, and preventing migraines. With its active ingredient Divalproex, it helps stabilize neuronal activity and mood. Proper dosage and administration under the guidance of a healthcare professional are essential to maximize benefits and minimize potential side effects. Regular monitoring and adherence to medical advice ensure the safe and effective use of DIOWELPREX 250 ORAL SOLUTION.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order NOW\n",
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"description": "BENZTETRA 25 contains the active ingredient tetrabenazine 25mg, a specialized medication used primarily to manage involuntary movements associated with neurological disorders. Tetrabenazine is classified as a vesicular monoamine transporter 2 (VMAT2) inhibitor and works by regulating the levels of neurotransmitters such as dopamine, serotonin, norepinephrine, and histamine in the brain. This correction of chemical imbalances helps reduce excessive and uncontrolled muscle movements. BENZTETRA 25 is especially valuable for patients suffering from movement disorders that significantly impact their daily functioning. It helps improve motor control, thereby enhancing quality of life for those affected. This medication is prescribed mainly to treat chorea—a movement disorder characterized by jerky, irregular, and uncontrollable muscle movements—that is caused by Huntington disease.\n\nWhat is BENZTETRA 25?\nBENZTETRA 25 is a therapeutic tablet containing tetrabenazine 25mg, designed to treat involuntary movements (chorea) linked to Huntington disease. It does not cure Huntington disease nor address cognitive or psychiatric symptoms of the disease but effectively reduces the severity of abnormal movements by altering neurotransmitter activity in the brain.\n\nUses of BENZTETRA 25\n\nTo treat chorea (a movement disorder) that is caused by Huntington disease.\n\nTo control involuntary muscle movements in Huntington’s disease patients.\n\nManagement of other hyperkinetic movement disorders as determined by a healthcare provider (such as tardive dyskinesia or Tourette syndrome in some cases).\n\nTo reduce excessive motor activity caused by abnormal nerve signaling in the brain, improving voluntary muscle control.\n\nSide Effects of BENZTETRA 25\n\nDrowsiness and fatigue, which may affect alertness.\n\nInsomnia or difficulty sleeping.\n\nNausea, vomiting, or abdominal discomfort.\n\nParkinsonism symptoms such as tremors, muscle rigidity, and slowed movements (bradykinesia).\n\nMood alterations including depression, anxiety, and in severe cases, suicidal thoughts.\n\nRare serious reactions like allergic responses, heart rhythm irregularities, or neuroleptic malignant syndrome (characterized by high fever, muscle stiffness).\n\nPrecautions Before Using BENZTETRA 25\n\nInform your doctor if you have a history of depression, suicidal thoughts, or any psychiatric illness.\n\nAvoid use if you have severe liver disease or have recently taken monoamine oxidase inhibitors (MAOIs).\n\nCaution in patients with cardiac issues due to potential QT interval prolongation.\n\nUse with care when driving or operating machinery as BENZTETRA 25 may cause dizziness or drowsiness.\n\nDo not stop the medication suddenly without consulting your healthcare provider, as symptoms might worsen.\n\nRegular monitoring by a healthcare professional is recommended to assess side effects and efficacy.\n\nDrug Interactions: What Drugs Interact with BENZTETRA 25?\n\nMAO inhibitors such as isocarboxazid, phenelzine, selegiline, and others can cause dangerous interactions and should not be used concurrently.\n\nOther drugs that affect serotonin levels, including selective serotonin reuptake inhibitors (SSRIs), may increase the risk of serotonin syndrome.\n\nCaution with other medications known to prolong the QT interval or those affecting dopamine systems.\n\nInteractions with neuroleptics or antipsychotics require close medical supervision due to additive effects on movement and mood.\n\nConclusion\nBENZTETRA 25, containing tetrabenazine 25mg, is a vital medication for managing chorea associated with Huntington disease by modulating neurotransmitter levels in the brain to reduce involuntary movements. While it offers substantial benefits in improving motor control, careful attention to side effects, precautions, and drug interactions is essential for safe and effective use. Always follow the guidance of a healthcare professional when using BENZTETRA 25 to ensure optimal outcomes and safety.",
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