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"name": "risedronate sodium tablets ip 35 mg",
"description": "Risedronate Sodium Tablets IP 35 mg\n\nMaintaining strong and healthy bones becomes increasingly important with age, especially for individuals at risk of osteoporosis or bone loss. Risedronate Sodium Tablets IP 35 mg is a clinically proven medication widely prescribed to strengthen bones, reduce fracture risk, and improve overall skeletal health. If you are considering this treatment, this buyer-focused guide will help you understand everything—from how it works to its benefits, dosage, precautions, and what to check before purchasing.\n\nWhat are Risedronate Sodium Tablets IP 35 mg?\n\nRisedronate Sodium Tablets IP 35 mg contains risedronate sodium, a medication that belongs to a class called bisphosphonates. These drugs are specifically designed to prevent bone breakdown and increase bone density.\n\nIt is commonly used to treat and prevent the following:\n\nOsteoporosis in postmenopausal women\nOsteoporosis in men\nBone loss due to long-term steroid use\nPaget’s disease of bone\n\nThis once-weekly dosage (35 mg) is convenient and effective for long-term bone health management.\n\nHow Do Risedronate Sodium Tablets IP 35 mg Work?\n\nBones are constantly being renewed through a process called bone remodeling, where old bone is broken down and new bone is formed. In conditions like osteoporosis, bone breakdown occurs faster than formation, leading to weak and fragile bones.\n\nMechanism of Action:\nRisedronate inhibits osteoclasts (cells responsible for bone breakdown)\nSlows down bone loss\nHelps maintain or increase bone density\nReduces the risk of fractures, especially in the spine and hips\n\nBy restoring balance in bone remodeling, this medication strengthens bones over time.\n\nKey Benefits of Risedronate Sodium Tablets IP 35 mg\n1. Strengthens Bones\n\nHelps increase bone mineral density, making bones stronger and less prone to fractures.\n\n2. Reduces Fracture Risk\n\nSignificantly lowers the risk of spine, hip, and other bone fractures.\n\n3. Convenient Weekly Dosage\n\nThe 35 mg tablet is typically taken once a week, improving patient compliance.\n\n4. Effective for Long-Term Use\n\nSuitable for ongoing treatment under medical supervision.\n\n5. Proven Clinical Safety\n\nWidely used and trusted by healthcare professionals worldwide.\n\nWho Should Consider Buying Risedronate Sodium Tablets IP 35 mg?\n\nThis medication is suitable for:\n\nPostmenopausal women at risk of osteoporosis\nMen diagnosed with low bone density\nPatients on long-term corticosteroid therapy\nIndividuals with a history of fractures due to weak bones\nPatients diagnosed with Paget’s disease\n\nImportant: Always consult a healthcare professional before starting this medication.\n\nDosage and Administration\n\nProper usage is crucial to ensure effectiveness and reduce side effects.\n\nGeneral Guidelines:\nUsually taken once weekly (same day each week)\nTake the tablet first thing in the morning\nSwallow with a full glass of plain water (not juice or milk)\nTake on an empty stomach\nImportant Instructions:\nDo not lie down for at least 30 minutes after taking the tablet\nAvoid eating or drinking anything else for 30 minutes\nDo not crush or chew the tablet\n\nFollowing these instructions helps prevent irritation of the esophagus and improves absorption.\n\nPossible Side Effects\n\nLike all medications, Risedronate Sodium Tablets IP 35 mg may cause side effects.\n\nCommon Side Effects:\nStomach pain\nIndigestion\nNausea\nJoint or muscle pain\nLess Common but Serious Side Effects:\nDifficulty swallowing\nSevere chest pain\nJaw pain (rare, associated with osteonecrosis)\nUnusual thigh bone fractures (rare)\n\nIf you experience severe or persistent symptoms, seek medical attention immediately.\n\nPrecautions and Warnings\n\nBefore using this medication, consider the following:\n\nMedical Conditions:\nInform your doctor if you have esophageal disorders\nPatients with kidney problems should use caution\nLow calcium levels should be corrected before starting treatment\nPregnancy and Breastfeeding:\nNot recommended unless prescribed\nConsult your doctor for guidance\nDrug Interactions:\n\nRisedronate may interact with the following:\n\nCalcium supplements\nAntacids\nIron supplements\n\nThese should be taken at a different time of day to avoid interference with absorption.\n\nStorage Instructions\n\nTo maintain the quality of the medication:\n\nStore in a cool, dry place\nKeep away from moisture and sunlight\nMaintain temperature below 25°C\nKeep out of reach of children\nBuying Guide: What to Check Before Purchase\n\nWhen purchasing Risedronate Sodium Tablets IP 35 mg, ensure the following:\n\nIt is prescribed by a qualified doctor\nThe product is from a reputable pharmaceutical brand\nPackaging is intact and properly sealed\nExpiry date is valid\nPurchased from a licensed pharmacy\n\nBulk buyers and distributors should source from trusted suppliers to ensure consistent quality and authenticity.\n\nWhy Choose Risedronate Sodium Tablets IP 35 mg?\n\nThis medication stands out due to:\n\nProven effectiveness in improving bone health\nConvenient once-weekly dosing\nReduced risk of fractures\nLong-term safety when monitored\nCost-effective treatment option\n\nFor individuals seeking reliable osteoporosis management, this tablet offers a practical and effective solution.\n\nFrequently Asked Questions (FAQs)\n1. How long does it take to see results?\n\nBone improvement may take several months, but fracture risk reduction begins earlier.\n\n2. Can I take it daily?\n\nNo, the 35 mg dose is typically taken once weekly.\n\n3. Is it safe for long-term use?\n\nYes, under medical supervision with regular monitoring.\n\n4. Can I take it with food?\n\nNo, it should be taken on an empty stomach for proper absorption.\n\n5. Do I need supplements with this medication?\n\nDoctors often recommend calcium and vitamin D supplements alongside treatment.\n\nLifestyle Tips for Better Bone Health\n\nTo maximize the benefits of Risedronate Sodium Tablets IP 35 mg:\n\nMaintain a calcium-rich diet\nEnsure adequate vitamin D intake\nEngage in weight-bearing exercises\nAvoid smoking and excessive alcohol consumption\nGet regular bone density tests\nConclusion\n\nRisedronate Sodium Tablets IP 35 mg is a trusted and effective solution for managing osteoporosis and improving bone strength. With its proven ability to reduce fracture risk and enhance bone density, it plays a vital role in long-term skeletal health.\n\nFor best results, follow your doctor’s instructions carefully, maintain a healthy lifestyle, and ensure regular medical check-ups. Choosing the right treatment today can significantly improve your bone health and overall quality of life in the future.",
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"name": "tiapride hydrochloride tablets",
"description": "TIAPRADE 50 tablets, containing Tiapride Hydrochloride 50mg, offer targeted relief for behavioral disorders and movement issues. This atypical antipsychotic helps manage symptoms like agitation and dyskinesia effectively.\n\nProduct Description\nTIAPRADE 50 is a prescription medication featuring Tiapride Hydrochloride as its active ingredient, each tablet delivering precisely 50mg of this compound. Manufactured to high pharmaceutical standards, these tablets are designed for oral administration, typically taken with water after meals to enhance absorption and minimize stomach upset. Tiapride belongs to the class of selective dopamine D2 and D3 receptor antagonists, distinguishing it from typical antipsychotics by its lower risk of extrapyramidal side effects. This makes TIAPRADE 50 particularly suitable for vulnerable populations, including the elderly.\n\nThe tablets are compact, film-coated for easy swallowing, and come in blister packs that protect against moisture and light. As a non-sedating option in many cases, TIAPRADE 50 supports daily functioning without excessive drowsiness, aligning with modern psychiatric care needs. For SEO optimization targeting “Tiapride Hydrochloride Tablets” or “TIAPRADE 50 uses,” this product stands out for its versatility in treating neuropsychiatric conditions.\n\nKey Uses and Applications\nTIAPRADE 50 excels in managing a range of psychiatric and neurological conditions rooted in dopamine imbalance. Primarily, it treats schizophrenia by controlling negative symptoms such as social withdrawal, lack of emotion, and poor concentration, helping patients reintegrate into society.\n\nIt is highly effective for behavioral disorders, including agitation, aggression, and impulsivity, especially in elderly patients with dementia or alcohol withdrawal syndrome. Clinically, TIAPRADE 50 addresses dyskinesia—involuntary movements of limbs or face—often linked to Parkinson's disease or long-term antipsychotic use. Other applications include Tourette's syndrome, tics, chorea in Huntington's disease, and even acute alcohol dependence delirium tremens.\n\nIn hospital settings, such as during COVID-19-related agitation, TIAPRADE 50 has shown promise due to its favorable safety profile. Dosage typically starts at 100-200mg three times daily (2-4 tablets of TIAPRADE 50), adjustable up to 600mg/day based on severity, age, and response. Full effects may take 4-6 weeks, so consistent use under medical supervision is essential.\n\nHow TIAPRADE 50 Works\nTIAPRADE 50 modulates dopamine activity in the brain's limbic system, blocking overactive D2 receptors without strongly affecting other neurotransmitters like serotonin or histamine. This selective action reduces psychotic symptoms, calms agitation, and suppresses abnormal movements while preserving cognitive function.\n\nUnlike broader antipsychotics, Tiapride's mechanism minimizes motor side effects, making it ideal for long-term dyskinesia management. It stabilizes mood swings in mania or schizophrenia, promoting clearer thinking and emotional balance. Patients often report improved sleep patterns and reduced anxiety within days, though optimal benefits build gradually.\n\nFor “Tiapride Hydrochloride Tablets mechanism,” this targeted dopamine inhibition underpins its efficacy across disorders, supported by decades of clinical data.\n\nKey Benefits\nTIAPRADE 50 delivers multifaceted benefits, enhancing quality of life for those with psychiatric challenges.\n\nRapid Symptom Control: Quickly reduces agitation and aggression, vital for elderly care or acute episodes.\n\nLow Extrapyramidal Risk: Unlike older antipsychotics, it rarely causes stiffness or tremors, ideal for dyskinesia patients.\n\nElderly-Friendly: Mild sedation profile supports geriatric use without impairing mobility or cognition.\n\nVersatile for Comorbidities: Effective in alcohol withdrawal, tics, and schizophrenia, reducing polypharmacy needs.\n\nImproved Daily Functioning: Boosts social engagement, attention, and emotional expression in psychosis.\n\nStudies affirm its tolerability, with many patients tolerating doses up to 600 mg daily long-term. Benefits extend to headache relief in some neurological cases and better outcomes in Tourette's management.\n\nBenefit\tTarget Condition\tAdvantage Over Alternatives\nAgitation Reduction\tElderly Behavioral Disorders\tLess sedation than benzodiazepines \nDyskinesia Control\tParkinson's-Related\tMinimal motor worsening \nNegative Symptom Relief\tSchizophrenia\tPreserves cognition \nWithdrawal Support\tAlcohol Dependence\tSafer in delirium tremens \nPotential Side Effects\nWhile generally well-tolerated, TIAPRADE 50 may cause mild, transient side effects that resolve with time or dose adjustment.\n\nCommon effects include drowsiness, dizziness, headache, insomnia, fatigue, and agitation—often fading after the first week. Less frequent are tremor, increased salivation, vertigo, orthostatic hypotension (dizziness on standing), and emotional blunting.\n\nRarely, overdose risks low blood pressure, sedation, or convulsions; seek immediate help if suspected. Avoid abrupt cessation to prevent rebound symptoms. Most resolve without intervention, but persistent issues warrant medical review.\n\nContraindications and Precautions\nDo not use TIAPRADE 50 if you have prolactinoma, pheochromocytoma, severe kidney/liver disease, heart conditions, convulsions history, or allergies to Tiapride. It's contraindicated in pregnancy, breastfeeding, children under 15, and those with epilepsy.\n\nPrecautions include monitoring prolactin levels, blood pressure, and liver function. Avoid alcohol, as it amplifies sedation. Drive cautiously until the effects are known. Drug interactions with antihypertensives or CNS depressants require dose tweaks.\n\nDosage Guidelines\nStart with 50-100mg (1-2 TIAPRADE 50 tablets) three times daily, post-meals. Maximum 600mg/day for adults; elderly may need lower doses (300mg/day). Adjust per response, not exceeding 4-6 weeks without reassessment. Swallow whole; store below 30°C.\n\nConclusion\nTIAPRADE 50 (Tiapride Hydrochloride Tablets 50 mg) stands as a reliable, SEO-highlighted solution for agitation, dyskinesia, schizophrenia, and behavioral disorders, balancing efficacy with safety. Its dopamine-selective action delivers key benefits like symptom control and preserved function, outweighing manageable side effects for suitable patients. Consult your doctor to integrate TIAPRADE 50 into your care plan for optimal mental health outcomes—empowering calmer, more productive lives.",
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"name": "Trazodone Hydrochloride 25 mg",
"description": "Mental health is just as important as physical health, yet it is often overlooked. Sleep disturbances, anxiety, and depression can deeply affect daily functioning, relationships, and overall quality of life. TORRANE 25, formulated with Trazodone Hydrochloride 25 mg, is a prescription medication designed to help individuals manage symptoms of depression and associated sleep disturbances.\n\nTORRANE 25 works by restoring the balance of certain neurotransmitters in the brain, particularly serotonin. By improving mood and promoting restful sleep, it supports emotional stability and mental well-being. This medication is often prescribed in low doses to help with insomnia related to depression or anxiety disorders.\n\nProduct Description\n\nTORRANE 25 contains Trazodone Hydrochloride 25 mg, an antidepressant that belongs to the class of serotonin antagonist and reuptake inhibitors (SARIs). Unlike traditional antidepressants that focus solely on serotonin reuptake inhibition, trazodone has a dual mechanism of action that enhances serotonin activity while also blocking certain serotonin receptors.\n\nThis unique action not only helps improve mood but also has calming and sedative properties, making it beneficial for patients who experience difficulty sleeping. The 25 mg dosage is often used as a starting dose or for patients who require lower strength for sleep-related issues.\n\nTORRANE 25 is formulated in tablet form for oral administration and is typically prescribed under medical supervision.\n\nHow TORRANE 25 Works\n\nThe effectiveness of TORRANE 25 lies in its influence on brain chemistry. Depression and anxiety disorders are often associated with imbalances in neurotransmitters, particularly serotonin.\n\nMechanism of Action\n\nSerotonin Reuptake Inhibition\nTrazodone prevents the reabsorption (reuptake) of serotonin into nerve cells, increasing its availability in the brain.\n\nSerotonin Receptor Antagonism\nIt blocks specific serotonin receptors that are linked to anxiety and sleep disturbances, providing calming effects.\n\nMild Sedative Effect\nThe medication has antihistaminic properties that promote relaxation and improve sleep quality.\n\nMood Stabilization\nBy enhancing serotonin activity, TORRANE 25 helps improve mood, reduce feelings of sadness, and enhance emotional balance.\n\nThis combined mechanism makes it particularly useful for patients with depression accompanied by insomnia.\n\nUses of TORRANE 25\n\nTORRANE 25 is commonly prescribed for:\n\nMajor depressive disorder (MDD)\n\nDepression associated with anxiety\n\nInsomnia related to depression\n\nSleep disturbances\n\nAnxiety-related symptoms\n\nWhile primarily indicated for depression, it is frequently used in lower doses to manage sleep problems due to its sedative properties.\n\nKey Benefits of TORRANE 25\n1. Improves Mood\n\nBy increasing serotonin levels, it helps reduce symptoms of depression such as sadness, hopelessness, and irritability.\n\n2. Promotes Restful Sleep\n\nIts calming effect makes it beneficial for individuals suffering from insomnia.\n\n3. Reduces Anxiety\n\nBlocking certain serotonin receptors can help alleviate anxiety symptoms.\n\n4. Enhances Daily Functioning\n\nImproved sleep and mood contribute to better focus, productivity, and overall quality of life.\n\n5. Lower Risk of Dependence\n\nUnlike some sleep medications, trazodone has a lower risk of dependency when used as prescribed.\n\nDosage and Administration\n\nThe dosage of Trazodone Hydrochloride 25 mg depends on the condition being treated and the patient’s medical history.\n\nFor sleep disturbances: 25–50 mg at bedtime.\n\nFor depression: Higher doses may be prescribed gradually under supervision.\n\nTablets should be taken after meals to reduce the risk of stomach upset. It is important to follow the physician’s instructions carefully and not adjust the dose without consultation.\n\nSide Effects of TORRANE 25\n\nLike all medications, TORRANE 25 may cause side effects. Most are mild and manageable, especially during the initial phase of treatment.\n\nCommon Side Effects\n\nDrowsiness\n\nDizziness\n\nDry mouth\n\nHeadache\n\nNausea\n\nBlurred vision\n\nConstipation\n\nThese side effects usually subside as the body adjusts to the medication.\n\nSerious Side Effects\n\nAlthough rare, serious side effects may occur:\n\nIrregular heartbeat\n\nSevere dizziness or fainting\n\nMood changes or worsening depression\n\nSuicidal thoughts (particularly in young adults)\n\nPriapism (prolonged painful erection in males)\n\nImmediate medical attention is required if any severe symptoms appear.\n\nPrecautions and Warnings\n\nInform your doctor about any history of heart disease, liver problems, or bipolar disorder.\n\nAvoid alcohol, as it may increase drowsiness.\n\nDo not operate heavy machinery until you know how the medication affects you.\n\nPregnant or breastfeeding women should consult their doctor before use.\n\nAbrupt discontinuation may cause withdrawal symptoms; tapering under medical supervision is recommended.\n\nWho Should Use TORRANE 25?\n\nTORRANE 25 is suitable for adults diagnosed with depression, anxiety-related disorders, or sleep disturbances. It is particularly helpful for individuals who struggle with both mood issues and insomnia.\n\nHowever, it should only be taken under prescription and regular follow-up with a healthcare professional.\n\nStorage Instructions\n\nStore at room temperature below 25°C.\n\nKeep away from moisture and direct sunlight.\n\nKeep out of reach of children.\nConclusion\nTORRANE 25 (Trazodone Hydrochloride 25 mg) is a versatile and effective medication used to manage depression and sleep disturbances. Its unique mechanism of action enhances serotonin levels while promoting relaxation, making it particularly beneficial for individuals experiencing mood disorders accompanied by insomnia.",
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"name": "Lopinavir 200mg Ritonavir 50mg",
"description": "RITONATERIS LP is a combination formulation containing Lopinavir and Ritonavir, two well-established antiretroviral agents that work together to inhibit viral replication. This fixed-dose combination is designed to enhance the effectiveness of treatment by improving drug levels and prolonging the action of lopinavir in the body.\n\nLopinavir belongs to the class of protease inhibitors, which act by blocking the protease enzyme essential for viral maturation. Ritonavir, although also a protease inhibitor, is primarily used here as a pharmacokinetic enhancer. It slows down the metabolism of lopinavir, allowing higher and more sustained concentrations in the bloodstream. This synergy makes RITONATERIS LP a reliable option in combination therapy regimens.\n\nManufactured with strict quality standards, RITONATERIS LP ensures consistent potency, stability, and performance. The formulation is intended for use as part of a broader therapeutic approach under professional supervision.\n\nUses of RITONATERIS LP\n\nRITONATERIS LP is primarily used in the management of viral infections where protease inhibition is required, particularly in combination regimens. It is not used as a standalone option but rather as part of a comprehensive treatment strategy.\n\nKey Uses Include:\n\nSuppression of viral replication by inhibiting protease enzyme activity\n\nReducing viral load when used in combination with other compatible agents\n\nSupporting long-term viral control strategies\n\nEnhancing treatment effectiveness through boosted drug exposure\n\nThis combination has been widely studied and utilized due to its dependable action and synergistic mechanism.\n\nHow RITONATERIS LP Works\n\nThe effectiveness of RITONATERIS LP lies in its dual-action mechanism:\n\nLopinavir\n\nInhibits the viral protease enzyme\n\nPrevents the virus from producing mature, infectious particles\n\nReduces the ability of the virus to multiply and spread\n\nRitonavir\n\nInhibits liver enzymes responsible for breaking down lopinavir\n\nIncreases the concentration and duration of lopinavir in the blood\n\nEnhances overall treatment efficiency\n\nTogether, these actions lead to sustained viral suppression and improved therapeutic outcomes when used correctly.\n\nKey Benefits of RITONATERIS LP\n1. Enhanced Effectiveness\n\nThe presence of ritonavir boosts lopinavir levels, ensuring consistent activity and reducing the risk of sub-therapeutic exposure.\n\n2. Proven Combination Strategy\n\nThe lopinavir-ritonavir combination has a long history of clinical use, making it a trusted choice in combination-based regimens.\n\n3. Reduced Dosing Complexity\n\nFixed-dose combinations like RITONATERIS LP simplify dosing schedules, which can improve adherence and continuity.\n\n4. Broad Compatibility\n\nRITONATERIS LP can be integrated into various combination protocols as advised by professionals.\n\n5. Stable and Reliable Formulation\n\nManufactured under controlled conditions, the product ensures uniform quality and performance across batches.\n\nDosage and Administration\n\nThe dosage of RITONATERIS LP depends on individual factors such as age, treatment plan, and combination regimen. It should always be taken exactly as prescribed.\n\nGeneral guidance includes:\n\nTablets are usually taken orally\n\nOften recommended with food to improve absorption\n\nConsistent timing helps maintain stable drug levels\n\nDo not alter the dose or discontinue use without professional guidance, as this may affect effectiveness.\n\nPossible Side Effects of RITONATERIS LP\n\nLike all combination formulations, RITONATERIS LP may cause side effects in some individuals. These effects are generally manageable and vary in intensity.\n\nCommon Side Effects\n\nNausea or vomiting\n\nDiarrhea or abdominal discomfort\n\nHeadache\n\nFatigue\n\nMild skin reactions\n\nThese effects often improve as the body adjusts to the formulation.\n\nLess Common Side Effects\n\nChanges in lipid levels\n\nAltered taste sensation\n\nSleep disturbances\n\nSerious Side Effects (Require Immediate Attention)\n\nSevere abdominal pain\n\nSigns of liver dysfunction such as yellowing of skin or eyes\n\nSevere allergic reactions\n\nIrregular heartbeat\n\nPrompt medical attention is necessary if serious reactions occur.\n\nPrecautions and Warnings\n\nInform your professional advisor about all other products you are using to avoid interactions\n\nRegular monitoring may be required to assess response and tolerance\n\nNot recommended without supervision in individuals with pre-existing liver conditions\n\nAdherence to the prescribed schedule is critical for effectiveness\n\nStorage Instructions\n\nStore at room temperature\n\nKeep away from moisture and direct sunlight\n\nKeep out of reach of children\nConclusion\nRITONATERIS LP, containing Lopinavir and Ritonavir, is a well-established combination designed to deliver reliable and sustained viral suppression as part of a broader therapeutic strategy. By combining a potent protease inhibitor with a pharmacokinetic enhancer, this formulation maximizes effectiveness while maintaining manageable dosing.",
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"name": "FABRICAL MG K₂7",
"description": "FABRICAL MG K₂7 represents a scientifically advanced nutritional supplement that combines essential minerals and vitamins in a synergistic formulation designed to support optimal bone health, cardiovascular function, and overall metabolic wellness. This innovative product brings together six critical nutrients—Calcium Citrate Maleate, Magnesium Bisglycinate, Vitamin D3, Vitamin K2-7 (Menaquinone-7), Zinc, and Methylcobalamin—in precise therapeutic ratios that maximize bioavailability and clinical effectiveness.\nUnlike conventional calcium supplements that focus solely on calcium supplementation, FABRICAL MG K₂7 adopts a comprehensive, multi-nutrient approach that addresses the complex interplay between various micronutrients essential for skeletal integrity, neuromuscular function, immune competence, and metabolic regulation. This sophisticated formulation reflects current understanding of nutritional biochemistry, recognizing that optimal health outcomes require balanced supplementation rather than isolated nutrient provision.\nThe product has been meticulously formulated to address the growing epidemic of nutritional deficiencies affecting diverse populations, from elderly individuals experiencing age-related bone loss to young adults with suboptimal dietary intake, pregnant women with increased nutritional demands, and individuals with chronic conditions affecting nutrient absorption or utilization. FABRICAL MG K₂7 serves as a convenient, evidence-based solution for maintaining nutritional adequacy and supporting long-term health across various life stages.\nDetailed Understanding of FABRICAL MG K₂7 Components\nCalcium Citrate Maleate: Superior Calcium Bioavailability\nCalcium Citrate Maleate represents the premium form of calcium supplementation, offering significantly enhanced absorption compared to traditional calcium carbonate. This advanced calcium complex demonstrates approximately 25-30% better bioavailability, making it particularly valuable for individuals with reduced gastric acid production, including elderly populations and those taking proton pump inhibitors or H2-receptor antagonists. Unlike calcium carbonate, which requires acidic conditions for optimal dissolution, Calcium Citrate Maleate can be absorbed efficiently regardless of meal timing or stomach pH, providing greater flexibility and convenience.\nThe maleate component further enhances calcium absorption and utilization by supporting cellular energy metabolism and mitochondrial function. This sophisticated formulation ensures that supplemented calcium reaches target tissues—bones, teeth, muscles, and nerves—where it performs essential physiological functions rather than accumulating in soft tissues where it could potentially contribute to unwanted calcification.\nMagnesium Bisglycinate: The Gentle Magnesium Choice\nMagnesium Bisglycinate, also known as magnesium glycinate, stands as one of the most bioavailable and well-tolerated forms of magnesium supplementation. This chelated form, where magnesium is bound to two molecules of the amino acid glycine, offers exceptional absorption rates approaching 80-90% while minimizing the gastrointestinal side effects—particularly diarrhea—commonly associated with other magnesium forms like magnesium oxide or sulfate.\nMagnesium plays over 300 enzymatic roles throughout the body, making it indispensable for energy production, protein synthesis, muscle and nerve function, blood glucose control, and blood pressure regulation. Within FABRICAL MG K₂7, magnesium works synergistically with calcium, maintaining the critical calcium-magnesium balance essential for proper muscular contraction and relaxation, cardiovascular rhythm stability, and skeletal mineralization.\nVitamin D3: The Sunshine Vitamin in Its Active Form\nVitamin D3 (cholecalciferol) represents the most bioactive form of vitamin D, identical to what human skin synthesizes upon ultraviolet B exposure. This fat-soluble vitamin functions more accurately as a hormone, regulating calcium absorption from the intestines, maintaining serum calcium and phosphorus concentrations within optimal ranges, and modulating bone remodeling by both osteoblasts and osteoclasts.\nBeyond skeletal functions, Vitamin D3 exerts profound influences on immune system regulation, cellular differentiation and proliferation, neuromuscular function, and inflammation modulation. Vitamin D receptors exist throughout the body—in tissues ranging from the brain and heart to immune cells and muscle—highlighting its systemic importance. The inclusion of Vitamin D3 in FABRICAL MG K₂7 ensures that supplemented calcium can be effectively absorbed and utilized, preventing the futility of calcium supplementation in vitamin D-deficient states.\nVitamin K2-7: The Missing Link in Bone and Cardiovascular Health\nVitamin K2-7, specifically the menaquinone-7 (MK-7) form, represents perhaps the most revolutionary component of FABRICAL MG K₂7. This long-chain vitamin K2 demonstrates superior bioavailability and longer half-life compared to vitamin K1 (phylloquinone) found in green vegetables or shorter-chain K2 forms. Vitamin K2-7's critical function involves activating proteins responsible for proper calcium utilization—specifically matrix Gla protein (MGP) and osteocalcin.\nOsteocalcin, produced by bone-building osteoblasts, requires vitamin K2-dependent carboxylation to become active and effectively bind calcium into bone matrix, strengthening skeletal structure. Simultaneously, Vitamin K2-7 activates MGP, which prevents calcium deposition in arterial walls and soft tissues, directing calcium away from cardiovascular structures where it contributes to atherosclerosis and arterial stiffness. This dual action—promoting bone calcification while preventing vascular calcification—makes Vitamin K2-7 uniquely valuable, addressing the “calcium paradox” where individuals may simultaneously experience osteoporosis and arterial calcification.\nZinc: The Multifunctional Essential Mineral\nZinc, incorporated into FABRICAL MG K₂7 in highly bioavailable form, serves numerous critical physiological functions spanning immune competence, wound healing, protein synthesis, DNA synthesis, and cellular division. Regarding bone health specifically, zinc influences bone metabolism by supporting osteoblast activity and collagen synthesis, contributing to bone matrix formation and mineralization. Zinc also functions as a cofactor for alkaline phosphatase, an enzyme essential for bone mineralization.\nBeyond skeletal contributions, zinc supports immune system function, acting as a critical component of innumerable enzymes involved in immune cell development and function. Zinc deficiency impairs both innate and adaptive immunity, increasing susceptibility to infections. The mineral also supports sensory function (taste and smell), cognitive function, reproductive health, and skin integrity.\nMethylcobalamin: The Bioactive Vitamin B12\nMethylcobalamin represents the active, coenzyme form of vitamin B12, requiring no metabolic conversion to exert biological activity. This form demonstrates superior neurological benefits compared to cyanocobalamin, the synthetic form commonly used in supplements. Methylcobalamin directly participates in methionine synthesis and methylation reactions critical for nervous system health, DNA synthesis, red blood cell formation, and homocysteine metabolism.\nElevated homocysteine, resulting from inadequate B12 status, associates with increased cardiovascular disease risk, cognitive decline, and bone fragility. By supporting homocysteine conversion to methionine, methylcobalamin in FABRICAL MG K₂7 contributes to cardiovascular protection and potentially supports bone health through mechanisms independent of its well-established neurological and hematological roles.\nPrimary Uses and Clinical Applications of FABRICAL MG K₂7\nComprehensive Bone Health Support\nThe primary indication for FABRICAL MG K₂7 centers on comprehensive bone health support across various life stages and clinical scenarios. The formulation addresses all critical aspects of skeletal health: providing adequate calcium substrate for mineralization, ensuring calcium absorption through Vitamin D3, directing calcium into bone matrix via Vitamin K2-7, supporting bone matrix formation through magnesium and zinc, and protecting against homocysteine-related bone fragility through methylcobalamin.\nThis makes FABRICAL MG K₂7 particularly valuable for:\nOsteoporosis Prevention and Management: Postmenopausal women and elderly men experiencing age-related bone loss benefit from the formulation's comprehensive approach, potentially slowing bone density decline and reducing fracture risk.\nGrowing Children and Adolescents: During peak bone-building years, FABRICAL MG K₂7 supports optimal skeletal development, helping children and teenagers achieve maximum peak bone mass—a critical determinant of lifelong skeletal health.\nPregnancy and Lactation: Women during pregnancy and breastfeeding experience dramatically increased calcium demands. FABRICAL MG K₂7 helps prevent maternal bone density loss while supporting fetal skeletal development.\nCardiovascular Protection Through Proper Calcium Distribution\nThe Vitamin K2-7 component positions FABRICAL MG K₂7 as more than a bone health supplement—it's a cardiovascular protective formulation. By activating matrix Gla protein, the supplement helps prevent arterial calcification, potentially reducing cardiovascular disease risk. This dual benefit addresses the concerning observation that some individuals taking calcium supplements without adequate Vitamin K2 may experience increased cardiovascular events due to inappropriate calcium deposition in arterial walls.\nNeurological and Cognitive Support\nThe methylcobalamin component provides neurological support, particularly valuable for elderly individuals at risk for vitamin B12 deficiency due to reduced intrinsic factor production or those taking medications that impair B12 absorption (such as metformin or proton pump inhibitors). Adequate B12 status supports cognitive function, mood regulation, nerve conduction, and may help prevent peripheral neuropathy.\nImmune System Enhancement\nBoth zinc and vitamin D3 within FABRICAL MG K₂7 contribute significantly to immune competence. Vitamin D modulates both innate and adaptive immunity, while zinc supports immune cell development and function. This immune support proves particularly relevant during seasonal illness peaks or for individuals with compromised immunity.\nMuscle Function and Exercise Performance\nMagnesium's role in muscle contraction and relaxation, combined with calcium's involvement in excitation-contraction coupling, makes FABRICAL MG K₂7 valuable for athletes and physically active individuals. The formulation may help prevent exercise-associated muscle cramps, support recovery, and maintain electrolyte balance.\nKey Benefits of FABRICAL MG K₂7\nEnhanced Bioavailability and Absorption\nUnlike basic supplements using inferior ingredient forms, FABRICAL MG K₂7 utilizes premium, highly bioavailable compounds:\n\nCalcium Citrate Maleate offers superior absorption compared to calcium carbonate\nMagnesium Bisglycinate provides excellent absorption without gastrointestinal distress\nVitamin D3 is more potent than D2\nVitamin K2-7 (MK-7) has longer half-life and better tissue distribution than K1 or shorter-chain K2 forms\nMethylcobalamin is the active B12 form requiring no conversion\n\nThis superior bioavailability means lower doses can achieve therapeutic effects, reducing pill burden and potential adverse effects while maximizing benefits.\nSynergistic Nutrient Interactions\nFABRICAL MG K₂7's formulation recognizes that nutrients work together, not in isolation:\n\nVitamin D3 enhances calcium absorption while Vitamin K2-7 directs where that calcium goes\nMagnesium supports Vitamin D activation and calcium metabolism\nZinc supports bone matrix formation complementing calcium's role in mineralization\nMethylcobalamin supports methylation pathways that may influence bone health\n\nThis synergy delivers benefits exceeding what individual nutrients could provide separately.\nComprehensive Rather Than Fragmented Nutritional Support\nRather than requiring multiple separate supplements, FABRICAL MG K₂7 provides comprehensive support in a single, convenient formulation. This simplification improves compliance, reduces costs compared to purchasing individual supplements, and eliminates concerns about nutrient imbalances from uncoordinated supplementation.\nProtection Against the Calcium Paradox\nPerhaps the most significant benefit stems from the Vitamin K2-7 inclusion, which addresses the calcium paradox—simultaneously strengthening bones while protecting cardiovascular health by preventing arterial calcification. This represents a critical advancement over traditional calcium supplements that may inadvertently increase cardiovascular risk when taken without adequate Vitamin K2.\nSupport Across Multiple Physiological Systems\nBeyond bones, FABRICAL MG K₂7 benefits:\n\nCardiovascular System: Through arterial protection and homocysteine management\nNervous System: Via methylcobalamin's neurological support\nImmune System: Through vitamin D3 and zinc's immunomodulatory effects\nMuscular System: Via magnesium and calcium's roles in contraction\nMetabolic System: Through magnesium's involvement in glucose metabolism\n\nThis multi-system support delivers value far exceeding simple bone health supplementation.\nPotential Side Effects and Safety Considerations\nGenerally Well-Tolerated with Minimal Side Effects\nFABRICAL MG K₂7, when taken as directed, demonstrates excellent tolerability in most individuals. The selection of highly bioavailable, gentle nutrient forms specifically minimizes adverse effects common with inferior formulations.\nMild Gastrointestinal Effects\nSome users may initially experience mild digestive symptoms including:\n\nSlight nausea, particularly if taken on an empty stomach\nMinor bloating or gas\nMild constipation (though less likely than with calcium carbonate formulations)\n\nThese effects typically resolve within a few days as the body adjusts and can be minimized by taking the supplement with meals and ensuring adequate hydration.\nRare Allergic Reactions\nAlthough uncommon, some individuals may experience hypersensitivity to ingredients or excipients in the formulation. Signs include rash, itching, or swelling. Discontinuation and medical consultation are warranted if such reactions occur.\nConsiderations for Specific Populations\nIndividuals on Anticoagulants: Vitamin K2, while generally safer regarding coagulation than K1, may theoretically interact with warfarin. Patients on anticoagulation therapy should consult healthcare providers before starting FABRICAL MG K₂7, though recent evidence suggests K2 supplementation at consistent doses may not significantly affect INR stability.\nKidney Disease Patients: Individuals with chronic kidney disease should consult nephrologists before supplementing with calcium, magnesium, or vitamin D due to altered mineral metabolism and increased calcification risks in renal impairment.\nHypercalcemia Risk: Those with conditions predisposing to elevated calcium (hyperparathyroidism, sarcoidosis, certain cancers) should avoid supplementation without medical supervision.\nImportance of Appropriate Dosing\nExceeding recommended doses may increase adverse effect risks including:\n\nHypercalcemia (excessive calcium) causing nausea, constipation, kidney stones\nHypermagnesemia (excessive magnesium) causing diarrhea, cardiac abnormalities\nVitamin D toxicity (though requiring very high doses sustained over time)\n\nFollowing manufacturer's recommendations and consulting healthcare providers regarding individual needs ensures safe, effective use.\nRecommended Usage and Dosage Guidelines\nFABRICAL MG K₂7 should be taken according to manufacturer recommendations, typically one to two tablets daily with meals for optimal absorption of fat-soluble vitamins (D3 and K2-7). Taking the supplement with food containing some dietary fat further enhances absorption of these critical nutrients while minimizing potential gastrointestinal discomfort.\nConsistency in timing supports optimal benefits, as regular daily supplementation maintains stable nutrient levels. For individuals on multiple medications, spacing FABRICAL MG K₂7 administration at least two hours from certain medications (particularly thyroid hormones, bisphosphonates, or antibiotics) prevents potential absorption interference.\nIndividual requirements vary based on age, sex, dietary intake, health status, and specific deficiency risks. Healthcare provider consultation helps determine whether standard dosing suffices or whether adjustments are warranted. Periodic monitoring of vitamin D levels and other relevant biomarkers may be recommended to ensure supplementation achieves therapeutic goals without overshooting into excess.\nConclusion: FABRICAL MG K₂7 as a Comprehensive Nutritional Solution\nFABRICAL MG K₂7 stands as a sophisticated, scientifically formulated nutritional supplement that transcends traditional approaches to bone health support. By combining six synergistic nutrients in highly bioavailable forms, this innovative product addresses the complex, interconnected nature of skeletal health, cardiovascular protection, neurological function, and overall metabolic wellness.\nThe formulation's greatest strength lies in its comprehensive approach—recognizing that optimal health outcomes require balanced nutrition rather than isolated nutrient provision. The inclusion of Vitamin K2-7 particularly distinguishes FABRICAL MG K₂7 from conventional calcium supplements, addressing the critical calcium paradox and ensuring supplemented calcium strengthens bones while protecting cardiovascular structures.\nFor individuals seeking to support bone density, prevent osteoporosis, ensure adequate nutritional status during life stages of increased demand, or simply maintain optimal health through evidence-based supplementation, FABRICAL MG K₂7 offers a convenient, effective solution backed by nutritional science. Its excellent tolerability, superior ingredient quality, and multi-system benefits make it suitable for diverse populations from growing adolescents to active adults and elderly individuals concerned about age-related health challenges.\nAs with any nutritional supplement, FABRICAL MG K₂7 works best as part of a comprehensive health strategy including balanced nutrition, regular physical activity, adequate sleep, stress management, and appropriate medical care. It complements rather than replaces healthy lifestyle practices, providing nutritional insurance that helps fill gaps in modern diets while supporting long-term wellness.\nWhether you're proactively supporting your skeletal health, addressing identified nutritional deficiencies, or seeking comprehensive multi-nutrient support, FABRICAL MG K₂7 represents a premium choice that combines scientific sophistication with practical convenience, delivering measurable benefits that support vibrant health across all life stages.\n\nDisclaimer: This information is for educational purposes and does not constitute medical advice. Individual nutritional needs vary significantly based on numerous factors. Consult qualified healthcare professionals before starting any supplement regimen, particularly if you have existing health conditions, take medications, are pregnant or nursing, or have specific health concerns. Keep supplements out of reach of children and store according to manufacturer recommendations to maintain product integrity and safety.",
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"description": "ESMOSTRUM IT: Comprehensive Product Guide\nProduct Overview\nESMOSTRUM IT is an advanced pharmaceutical formulation that combines two potent active ingredients—Esomeprazole and Itopride—to provide comprehensive relief from gastrointestinal disorders. This dual-action medication represents a significant advancement in the management of acid-related digestive conditions and motility disorders. By combining a proton pump inhibitor with a prokinetic agent, ESMOSTRUM IT addresses both the underlying causes and symptomatic manifestations of various digestive ailments, offering patients a complete therapeutic solution in a single, convenient dosage form.\nThe synergistic combination of Esomeprazole and Itopride makes ESMOSTRUM IT particularly effective for individuals suffering from gastroesophageal reflux disease (GERD), functional dyspepsia, and other conditions where both excessive acid production and impaired gastric motility contribute to discomfort and disease progression.\nActive Pharmaceutical Ingredients\nEsomeprazole\nEsomeprazole is the S-isomer of omeprazole and belongs to the class of medications known as proton pump inhibitors (PPIs). It works by specifically and irreversibly blocking the hydrogen-potassium adenosine triphosphatase enzyme system (the proton pump) located in the gastric parietal cells. This mechanism effectively reduces gastric acid secretion, providing sustained relief from acid-related symptoms and allowing damaged esophageal and gastric tissue to heal.\nItopride\nItopride is a prokinetic agent that enhances gastrointestinal motility through a dual mechanism of action. It acts as both a dopamine D2 receptor antagonist and an acetylcholinesterase inhibitor. By blocking dopamine receptors, it removes the inhibitory effect of dopamine on gastrointestinal motility, while its acetylcholinesterase inhibition increases acetylcholine levels, further promoting coordinated gastric contractions and improved gastric emptying.\nTherapeutic Uses and Indications\nESMOSTRUM IT is prescribed for a wide range of gastrointestinal conditions where both acid suppression and enhanced motility are therapeutically beneficial:\nGastroesophageal Reflux Disease (GERD)\nESMOSTRUM IT provides exceptional relief for patients suffering from GERD, a chronic condition where stomach acid frequently flows back into the esophagus. The esomeprazole component reduces acid production, while itopride improves the tone of the lower esophageal sphincter and accelerates gastric emptying, thereby reducing the frequency and severity of reflux episodes.\nFunctional Dyspepsia\nFor patients experiencing persistent or recurrent upper abdominal discomfort without an identifiable organic cause, ESMOSTRUM IT addresses multiple pathophysiological mechanisms. It relieves symptoms such as early satiety, postprandial fullness, epigastric pain, and bloating by normalizing gastric acid levels and improving gastric accommodation and emptying.\nPeptic Ulcer Disease\nESMOSTRUM IT aids in the healing of gastric and duodenal ulcers by creating an optimal healing environment through sustained acid suppression. The prokinetic action of itopride helps prevent stasis of gastric contents, which can exacerbate ulcer symptoms.\nNon-Ulcer Dyspepsia\nMany patients experience dyspeptic symptoms without evidence of ulceration. ESMOSTRUM IT effectively manages these symptoms by addressing both acid hypersecretion and delayed gastric emptying, two key factors in non-ulcer dyspepsia.\nGastroparesis-Related Symptoms\nIn conditions where gastric emptying is significantly delayed, the itopride component of ESMOSTRUM IT helps restore more normal gastric motility patterns, reducing associated symptoms like nausea, vomiting, and abdominal distension.\nKey Benefits and Advantages\nDual Mechanism of Action\nThe primary advantage of ESMOSTRUM IT lies in its comprehensive approach to gastrointestinal health. Rather than addressing only acid production or motility in isolation, this combination therapy tackles both aspects simultaneously, providing more complete symptom relief and better therapeutic outcomes.\nSuperior Acid Suppression\nEsomeprazole offers more consistent and prolonged acid suppression compared to many other acid-reducing medications. It provides sustained relief throughout the day and night, allowing patients to experience fewer breakthrough symptoms and better quality of life.\nEnhanced Gastric Motility\nThe itopride component specifically targets motility issues without crossing the blood-brain barrier significantly, meaning it provides prokinetic benefits with minimal central nervous system side effects. This results in improved gastric emptying, reduced bloating, and decreased feelings of fullness after meals.\nRapid Symptom Relief\nMany patients experience noticeable improvement in their symptoms within the first few days of treatment with ESMOSTRUM IT. The combination therapy addresses multiple symptom pathways simultaneously, leading to faster and more comprehensive relief.\nImproved Quality of Life\nBy effectively managing symptoms such as heartburn, regurgitation, nausea, bloating, and early satiety, ESMOSTRUM IT significantly enhances patients' daily functioning and overall well-being. Patients report better sleep quality, improved dietary tolerance, and reduced anxiety related to their digestive symptoms.\nConvenient Dosing\nThe combination of two active ingredients in a single formulation improves medication adherence by reducing pill burden. Patients appreciate the simplicity of taking one medication instead of multiple separate preparations.\nMucosal Healing Properties\nBeyond symptom relief, ESMOSTRUM IT promotes actual healing of damaged esophageal and gastric mucosa. The reduced acid environment created by esomeprazole allows inflamed and eroded tissue to regenerate properly.\nReduced Risk of Complications\nBy effectively controlling acid reflux and improving gastric emptying, ESMOSTRUM IT helps prevent potential complications of chronic GERD, such as esophageal strictures, Barrett's esophagus, and respiratory complications from aspiration.\nDosage and Administration\nESMOSTRUM IT should be taken exactly as prescribed by a healthcare professional. Typically, the medication is administered orally, preferably before meals to optimize its therapeutic effects. The standard dosing regimen usually involves once or twice daily administration, though individual requirements may vary based on the severity of the condition and patient response.\nThe medication should be swallowed whole with water and should not be crushed, chewed, or split, as this may affect the drug's release mechanism and therapeutic efficacy. Patients should maintain regular dosing schedules to ensure optimal acid suppression and motility enhancement throughout the day.\nSide Effects and Safety Considerations\nLike all medications, ESMOSTRUM IT may cause side effects in some individuals, though not everyone experiences them. Understanding potential adverse effects helps patients identify and report concerning symptoms promptly.\nCommon Side Effects\nGastrointestinal Effects: Some patients may experience diarrhea, constipation, abdominal pain, nausea, or flatulence, particularly during initial treatment. These effects are usually mild and often resolve as the body adjusts to the medication.\nHeadache: Mild to moderate headaches occur in a small percentage of patients and typically diminish with continued use.\nDizziness: Some individuals may experience lightheadedness or dizziness, particularly when standing up quickly.\nDry Mouth: Reduced saliva production may occur, leading to oral dryness and discomfort.\nLess Common Side Effects\nSkin Reactions: Rash, itching, or other dermatological manifestations may develop in sensitive individuals.\nSleep Disturbances: Some patients report insomnia or unusual dreams while taking the medication.\nIncreased Prolactin Levels: Itopride may cause mild elevation in prolactin levels, though clinical manifestations are rare.\nTaste Alterations: Changes in taste perception or metallic taste may occur temporarily.\nSerious Side Effects (Rare)\nWhile uncommon, certain serious adverse effects require immediate medical attention:\n\nSevere allergic reactions including difficulty breathing, facial swelling, or severe skin reactions\nSevere diarrhea that persists or contains blood\nIrregular heartbeat or palpitations\nMuscle weakness or pain\nSeizures or tremors\nSigns of liver problems including jaundice, dark urine, or persistent nausea\n\nLong-Term Considerations\nExtended use of proton pump inhibitors like esomeprazole has been associated with certain risks that patients should discuss with their healthcare providers:\n\nPotential reduction in calcium, magnesium, and vitamin B12 absorption\nSlightly increased risk of bone fractures with prolonged use\nPossible increased susceptibility to certain gastrointestinal infections\nRare cases of kidney problems\n\nRegular monitoring and periodic assessment by healthcare professionals help minimize these risks while maintaining therapeutic benefits.\nPrecautions and Contraindications\nPatients should inform their healthcare provider about all existing medical conditions, particularly liver disease, kidney problems, osteoporosis, low magnesium levels, or any gastrointestinal bleeding. ESMOSTRUM IT may interact with certain medications, including blood thinners, antifungals, HIV medications, and certain antibiotics. A complete medication review ensures safe and effective therapy.\nPregnant or breastfeeding women should only use ESMOSTRUM IT under strict medical supervision, as the safety profile in these populations requires careful consideration of potential risks and benefits.\nLifestyle Recommendations\nFor optimal therapeutic outcomes, patients taking ESMOSTRUM IT should complement their medication regimen with appropriate lifestyle modifications:\n\nAvoid trigger foods that exacerbate acid reflux, such as spicy foods, citrus, chocolate, caffeine, and alcohol\nMaintain a healthy body weight to reduce abdominal pressure\nEat smaller, more frequent meals rather than large portions\nAvoid lying down immediately after eating; wait at least two to three hours\nElevate the head of the bed if nighttime symptoms occur\nQuit smoking, as tobacco use significantly worsens reflux symptoms\nManage stress through relaxation techniques, as stress can exacerbate digestive symptoms\n\nConclusion\nESMOSTRUM IT represents a sophisticated and effective pharmaceutical solution for individuals struggling with complex gastrointestinal disorders involving both acid hypersecretion and impaired motility. By combining the powerful acid-suppressing capabilities of esomeprazole with the prokinetic benefits of itopride, this medication offers comprehensive symptom management that addresses the multifaceted nature of digestive disorders.",
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"name": "Opipramol Dihydrochloride 100 mg",
"description": "OPIRAPROL 100, featuring Opipramol Dihydrochloride 100 mg, stands out as a reliable medication from Steris Healthcare Pvt Ltd designed to address anxiety disorders and related somatic issues. This tricyclic compound offers targeted relief by modulating brain chemicals for better emotional balance. Patients often find it helps restore daily functionality without the heavier sedation of some alternatives.\n\n\nProduct Overview\nOPIRAPROL 100 contains 100 mg of Opipramol Dihydrochloride per tablet, a dibenzazepine derivative primarily classified as an anxiolytic with antidepressant properties. Manufactured by Steris Healthcare Pvt Ltd, it targets generalized anxiety disorder (GAD) and somatoform disorders, where physical symptoms like unexplained pain or fatigue stem from psychological stress. Unlike typical antidepressants that focus solely on serotonin reuptake, Opipramol acts as a sigma-1 receptor agonist, influencing calcium signaling and neurotransmitter release for a calming effect.\n\n\nThe formulation ensures steady absorption, making it suitable for adults needing moderate to higher dosing. Each pack typically includes 10 tablets, priced accessibly for ongoing therapy under medical supervision. Steris emphasizes quality with WHO-GMP certification, positioning OPIRAPROL 100 as a trusted option in India's mental health market.\n\n\nHow It Works\nOpipramol Dihydrochloride in OPIRAPROL 100 primarily binds to sigma receptors in the brain, promoting translocation to cell membranes and enhancing neurotransmitter modulation, especially serotonin and dopamine. This biphasic action first reduces acute tension and insomnia, then stabilizes mood over time by downregulating sigma-2 sites during chronic use.\n\n\nIt also exhibits mild antihistamine and anticholinergic effects, contributing to its sedative properties without strong reuptake inhibition like classic tricyclics. By calming overactive neural pathways, it alleviates the cycle of worry and physical unease, allowing clearer thinking and restful sleep. Clinical studies highlight its efficacy in somatoform cases, where patients fixate on bodily sensations amplified by anxiety.\n\n\nKey Uses\nHealthcare providers prescribe OPIRAPROL 100 for several interconnected conditions rooted in anxiety.\n\nGeneralized anxiety disorder, easing excessive worry, restlessness, and irritability that disrupt work and relationships.\n\n\nSomatoform disturbances target fatigue, pain, or gastrointestinal issues without clear organic cause.\n\n\nMild depressive episodes with prominent anxiety, supporting mood without full antidepressant escalation.\n\n\nAdjunctive therapy for sleep bruxism or insomnia linked to stress, based on emerging evidence.\n\n\nIn practice, it suits patients in high-stress environments, like urban professionals in Jaipur facing daily pressures, helping them regain focus and productivity.\n\n\nKey Benefits\nUsers of OPIRAPROL 100 report transformative effects that extend beyond symptom relief.\n\nRapid anxiety reduction promotes mental clarity, enabling better concentration and decision-making in daily tasks.\n\n\nMood stabilization balances emotional swings, fostering stronger interpersonal connections and resilience.\n\n\nEnhanced sleep quality combats insomnia, leading to refreshed mornings and sustained energy.\n\n\nImproved daily functioning boosts productivity, which is vital for professionals balancing career and personal life.\n\n\nLower sedation profile compared to benzodiazepines allows safe use during daytime hours.\n\n\nLong-term, it enhances quality of life by breaking anxiety cycles, with many patients noting fewer somatic complaints after consistent use.\n\n\nDosage Guidelines\nTake OPIRAPROL 100 as directed, typically 100 mg once or twice daily for adults, swallowed whole with water, with or without food. Start low to assess tolerance, adjusting up to 300 mg daily for severe cases under supervision.\n\n\nFor children over 6, dosing follows 3 mg/kg body weight, but adult use predominates. Maintain consistent timing to stabilize blood levels, and taper gradually to avoid withdrawal. Missed doses should resume normally without doubling.\n\nPotential Side Effects\nMost side effects of OPIRAPROL 100 are mild and diminish with time, but monitoring remains essential.\n\nCommon ones (1-10%) include dry mouth, nasal congestion, fatigue, dizziness, and orthostatic hypotension, often resolving as the body adjusts.\n\nOccasional (0.1-1%) effects encompass constipation, weight gain, tremor, blurred vision, tachycardia, and mild liver enzyme elevation.\nRare issues (<0.1%) like allergic rashes, urinary retention, confusion, or leukopenia require immediate medical attention, especially in elderly patients or those with heart conditions.\n\nPrecautions\nAvoid OPIRAPROL 100 in acute glaucoma, urinary retention, ileus, or uncontrolled epilepsy due to anticholinergic risks.\n\nPregnant or lactating women need doctor approval, as safety data limits use. Steer clear of alcohol and CNS depressants to prevent amplified drowsiness.\n\nMonitor heart rhythm in bradycardia patients and liver function during prolonged therapy. Abrupt stops can trigger rebound anxiety.\nWhen to Consult a Doctor\nSeek prompt advice if side effects intensify, mood worsens paradoxically, or new symptoms like chest pain emerge. Regular check-ins ensure optimal dosing, particularly for those on interacting meds like MAOIs.\n\nConclusion\nOPIRAPROL 100 with Opipramol Dihydrochloride 100 mg delivers effective, balanced relief for anxiety and somatic disorders, empowering users toward calmer, more productive lives. Backed by Steris Healthcare's commitment to quality, it bridges the gap between symptom management and holistic well-being when used responsibly. Always prioritize professional guidance to maximize benefits while minimizing risks.\n",
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"description": "LINALIGIP EMPAMET (Empagliflozin, Linagliptin, and Metformin Hydrochloride ER Tablets) stands out as a comprehensive triple therapy for adults with type 2 diabetes mellitus, combining three synergistic agents to tackle hyperglycemia from multiple angles. This once-daily extended-release formulation simplifies adherence while delivering robust glycemic control, weight management, and cardiovascular protection. Patients often seek it for its convenience in managing blood sugar levels when diet, exercise, and single agents fall short.\n\n\nProduct Description and Composition\nLINALIGIP EMPAMET features Empagliflozin (typically 10-25mg), Linagliptin (5 mg), and Metformin Hydrochloride ER (up to 1000mg) in a single tablet, designed for prolonged release to minimize gastrointestinal upset. Empagliflozin, an SGLT2 inhibitor, blocks glucose reabsorption in the kidneys, promoting its excretion via urine. Linagliptin, a DPP-4 inhibitor, enhances incretin hormones like GLP-1 to boost insulin secretion and suppress glucagon. Metformin ER reduces hepatic glucose production and improves insulin sensitivity without hypoglycemia risk.\n\n\nThis unique blend from Steris Healthcare ensures steady drug delivery over 24 hours, reducing peak-trough fluctuations for stable HbA1c reductions of 1.5-2.0%. The extended-release metformin coats the tablet core, dissolving gradually in the intestines for better tolerability compared to immediate-release forms. Ideal for Indian patients facing rising diabetes prevalence, it addresses insulin resistance, postprandial spikes, and caloric overload holistically.\n\n\nMechanism of Action\nThe triple mechanism targets key diabetes pathways: Empagliflozin inhibits SGLT2 in proximal renal tubules, lowering blood glucose by 70-90g daily through glycosuria, independent of insulin. Linagliptin selectively binds DPP-4, prolonging GLP-1 and GIP activity to stimulate glucose-dependent insulin release from beta cells and curb glucagon-mediated gluconeogenesis. Metformin activates AMPK in hepatocytes, inhibiting gluconeogenesis while enhancing peripheral glucose uptake.\n\n\nSynergy amplifies effects—SGLT2 inhibition provides insulin-independent control, DPP-4 boosts prandial responses, and metformin tackles fasting hyperglycemia—resulting in complementary HbA1c drops without overlapping toxicities. Clinical data show this combination yields superior efficacy over dual therapies, with added osmotic diuresis aiding fluid balance.\n\n\nUses and Indications\nLINALIGIP EMPAMET treats type 2 diabetes in adults, as adjunct to diet and exercise, especially when metformin alone or dual therapy inadequately controls glycemia. Primary uses include newly diagnosed patients needing intensification, those with obesity (due to weight loss from glycosuria), and high-risk cardiovascular profiles benefiting from empagliflozin's heart protection. It excels in managing postprandial hyperglycemia, fasting glucose, and preventing complications like nephropathy.\n\n\nPrescribed for patients intolerant to other agents or requiring simplified regimens, it suits Indian demographics with high metabolic syndrome rates. Not for type 1 diabetes or ketoacidosis; renal function (eGFR >45 mL/min) guides initiation.\n\n\nKey Benefits\nLINALIGIP EMPAMET offers multifaceted advantages for long-term diabetes management:\n\nSuperior Glycemic Control: Achieves 1.8% HbA1c reduction in trials, outperforming monotherapies by targeting multiple defects.\n\n\nWeight Loss: Empagliflozin induces 3-5kg loss via caloric excretion, countering metformin's neutral effect.\n\n\nCardiovascular and Renal Protection: Reduces major adverse cardiac events (MACE) by 14% and slows CKD progression, per EMPA-REG outcomes.\n\n\nLow Hypoglycemia Risk: Glucose-dependent actions of linagliptin and empagliflozin minimize lows, unlike sulfonylureas.\n\n\nConvenience: Single-tablet ER dosing improves compliance, vital for busy lifestyles in Jaipur and beyond.\n\n\nBlood Pressure Reduction: Mild diuretic effect lowers systolic BP by 3-5 mmHg.\n\n\nThese benefits enhance quality of life, reducing fatigue, neuropathy risks, and healthcare costs.\n\nSide Effects\nCommon side effects mirror individual components but occur less due to synergy:\n\nGastrointestinal: Metformin ER causes less nausea/diarrhea (10-15%) than IR forms; titrate slowly.\n\n\nGenitourinary: Empagliflozin raises UTI/genital mycotic infection risk (5-10%), managed with hygiene.\n\n\nVolume Depletion: Orthostatic hypotension in 2-3%, especially with diuretics.\n\n\nSerious effects include lactic acidosis (rare, <1/100,000 with metformin in eGFR >30), ketoacidosis (euglycemic, 0.1%), and acute kidney injury. Monitor for dehydration, pancreatitis signs, or bullous pemphigoid with linagliptin. Hypersensitivity rash or bone fractures warrant discontinuation.\n\n\nSide Effect Category\tFrequency\tManagement\nNausea and Diarrhea\tCommon (10%)\tTake with food, slow titration \n\nUTI/Mycotic Infections\tCommon (7%)\tHydration, antifungals \n\nHypoglycemia\tRare (<2%)\tWith insulin, dose adjust \n\nLactic Acidosis\tVery Rare.\tAvoid in renal/hepatic failure \n\nKetoacidosis\tRare (0.1%)\tCheck ketones if nausea \n\nDosage and Administration\nStart with Empagliflozin 10mg/Linagliptin 5mg/Metformin ER 1000mg once daily with morning meal to optimize absorption and reduce GI effects. Titrate metformin to 2000mg max based on tolerance; empagliflozin to 25mg if needed. Swallow whole; no crushing. Adjust for renal impairment (eGFR 30-45: max metformin 1000mg; <30 contraindicated). Elderly start low due to volume sensitivity.\n\n\nMissed dose: Take soon if less than 12 hours late; skip otherwise. Discontinue pre-surgery or contrast use.\n\nPrecautions and Warnings\nAssess eGFR before and 3-6 months after initiation; hold if <45. Caution in dehydration, heart failure, or liver disease risks lactic acidosis. Educate on ketoacidosis symptoms (nausea, fatigue) despite normal glucose. Avoid excessive alcohol; monitor BP in hypertensives. Pregnancy category D—use insulin instead. Breastfeeding is contraindicated.\n\n\nDrug interactions: Adding sulfonylureas/insulin heightens hypoglycemia; rifampin reduces linagliptin levels; ritonavir boosts empagliflozin exposure.\n\nFrequently Asked Questions\nWhat is LINALIGIP EMPAMET used for?\nControls type 2 diabetes via triple action on glucose excretion, incretins, and insulin sensitivity.\n\nDoes it cause weight gain?\nNo—it promotes 2-4 kg loss, unlike some antidiabetics.\n\n\nSafe for kidneys?\nRenal-protective; monitor eGFR.\n\n\nHypoglycemia risk?\nMinimal without sulfonylureas.\n\nConclusion\nLINALIGIP EMPAMET revolutionizes type 2 diabetes care with its potent, convenient triple therapy, delivering glycemic mastery, weight benefits, and cardioprotection unmatched by singles or duos. Backed by landmark trials, it empowers patients toward complication-free lives when integrated with lifestyle changes. Consult physicians for personalized dosing to harness its full potential safely.",
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"description": "IMATIFLOW 400, containing Imatinib IP 400mg, represents a breakthrough in targeted cancer therapy, offering patients a precise weapon against specific malignancies. This oral medication belongs to the class of tyrosine kinase inhibitors, revolutionizing treatment for conditions once deemed challenging to manage. By blocking abnormal proteins that fuel cancer cell growth, IMATIFLOW 400 helps restore normal cellular function and improves quality of life for many users.\n\nProduct Overview\nIMATIFLOW 400 is a branded formulation of Imatinib mesylate 400mg, produced to high pharmaceutical standards for consistent efficacy and bioavailability. Each tablet delivers the active ingredient in a film-coated form, designed for once-daily administration with food to enhance absorption and minimize gastrointestinal upset. Developed for adult patients, it targets cancers driven by dysregulated tyrosine kinases like BCR-ABL, c-KIT, and PDGFR, making it a cornerstone in modern oncology protocols.\n\nThe medication's mechanism hinges on competitive inhibition at the ATP-binding site of these kinases, halting downstream signaling pathways that promote uncontrolled proliferation, survival, and metastasis of malignant cells. Unlike traditional chemotherapy, which broadly attacks dividing cells, IMATIFLOW 400 spares most healthy tissues, leading to a more favorable safety profile. Clinical data from pivotal trials underscore its role as first-line therapy, with high response rates observed within months of initiation.\n\nPrimary Uses\nIMATIFLOW 400 excels in treating chronic myeloid leukemia (CML), particularly in the chronic phase where it induces deep molecular responses in over 80% of patients. It suppresses the Philadelphia chromosome-positive cells hallmark of CML by inhibiting the BCR-ABL fusion protein, dramatically extending progression-free survival. For newly diagnosed patients, standard dosing starts at 400mg daily, often achieving complete cytogenetic remission.\n\nIn gastrointestinal stromal tumors (GIST), IMATIFLOW 400 targets KIT or PDGFRA mutations, shrinking unresectable tumors and delaying progression in advanced cases. The recommended dose remains 400mg once daily, with potential escalation to 600-800mg for resistant strains, as per oncology guidelines. It also finds application in dermatofibrosarcoma protuberans (DFSP), aggressive systemic mastocytosis, and certain myelodysplastic syndromes, broadening its utility in precision medicine.\n\nHealthcare providers monitor response via PCR for BCR-ABL transcripts in CML or imaging for GIST, adjusting therapy based on milestones like major molecular response. Patients with Ph+ acute lymphoblastic leukemia (ALL) may receive it adjunctively, enhancing outcomes when combined with chemotherapy. Overall, IMATIFLOW 400 transforms these diseases from fatal to chronically manageable.\n\nKey Benefits\nOne standout benefit of IMATIFLOW 400 is its oral convenience, eliminating the need for frequent hospital visits associated with infusions. Response rates exceed 90% in early CML, with many patients achieving treatment-free remission after sustained deep responses, a paradigm shift from interferon-era therapies.\n\nTumor control in GIST prevents life-threatening complications like bowel obstruction, improving survival from months to years. Its specificity reduces severe toxicities, allowing patients to maintain daily activities, work, and social engagements with minimal disruption. Long-term studies report 10-year survival rates above 80% in CML, underscoring durable efficacy.\n\nAdditional advantages include cost-effectiveness over biologics and compatibility with supportive care like hydroxyurea for cytoreduction. Fluid retention, while common, responds well to diuretics, preserving cardiac function. For Indian patients, accessible pricing via brands like IMATIFLOW 400 supports equitable care in resource-limited settings.\n\nPotential Side Effects\nWhile generally well-tolerated, IMATIFLOW 400 can cause edema (swelling in legs or face) in up to 70% of users, managed by dose reduction or supportive measures. Gastrointestinal issues like nausea, vomiting, and diarrhea affect 40-50%, often resolving with antiemetics and dietary adjustments.\n\nMusculoskeletal pain, cramps, and fatigue occur frequently, alongside rash and abdominal discomfort. Hematologic effects include neutropenia or thrombocytopenia, necessitating regular blood counts. Rare but serious risks involve liver enzyme elevation, heart failure, or hemorrhage; prompt reporting of symptoms like shortness of breath or yellowing skin is crucial.\n\nAvoid grapefruit juice, as it elevates drug levels, and inform doctors of concurrent medications like CYP3A4 inhibitors. Pregnancy category D status advises contraception, with monitoring for growth retardation in exposed fetuses. Dizziness may impair driving, so caution is essential during initial weeks.\n\nDosage and Administration Guidelines\nSwallow IMATIFLOW 400 whole with a meal and full glass of water to optimize pharmacokinetics and reduce esophageal irritation. The standard adult dose for CML chronic phase is 400mg daily; for accelerated phase or blast crisis, 600mg. GIST dosing mirrors 400mg, titrated based on tolerance and response.\n\nRenal or hepatic impairment requires dose adjustments—reduce to 300-400mg in moderate cases. Do not crush or chew tablets. Missed doses should be taken promptly unless near the next, avoiding doubles. Long-term use demands quarterly monitoring of CBC, liver function, and ECG.\n\nPrecautions and Interactions\nPatients with a cardiac history need baseline echocardiograms, as QT prolongation or effusion risks exist. Drug interactions abound: St. John's wort induces metabolism, reducing efficacy; ketoconazole boosts levels. Vaccines, especially live ones, are contraindicated during therapy.\n\nRegular dermatologic checks mitigate skin cancer risk from prolonged use. Hydration combats fluid retention, and low-salt diets aid management. Steris Healthcare emphasizes patient education via counseling on adherence for optimal outcomes.\n\nConclusion\nIMATIFLOW 400 (Imatinib IP 400mg) stands as a testament to targeted therapy's power, offering robust control over CML, GIST, and related cancers with a balance of efficacy and manageability. Its benefits in prolonging life and enhancing daily functioning far outweigh transient side effects for most when monitored diligently. Consult oncologists for personalized plans, ensuring this innovative treatment maximizes hope and health in the fight against cancer.",
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