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{ "products": [ { "_id": "6662e4df2bed1f08484d7249", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Enzalutamide 160 mg Tablet", "description": "ENZULAMIDE 160\nEnzalutamide 160mg capsules represent a breakthrough in targeted therapy for advanced prostate cancer, specifically designed to inhibit androgen receptor signaling at multiple levels, slowing cancer progression even in castration-resistant cases. This oral medication, typically taken as a single daily 160mg dose (four 40mg capsules), binds directly to the androgen receptor, preventing nuclear translocation and DNA binding, which starves hormone-dependent prostate tumors of growth signals. Patients with metastatic castration-resistant prostate cancer (mCRPC), non-metastatic CRPC (nmCRPC), or metastatic castration-sensitive prostate cancer (mCSPC) benefit from its ability to delay disease advancement, reduce PSA levels, and extend progression-free survival.​\n\nAdministered continuously without cycling, enzalutamide 160mg maintains steady-state plasma levels for consistent anti-tumor activity, making it suitable for long-term management alongside standard care. Its role expands beyond initial hormone therapy failures, offering hope where traditional options falter.​\n\nProduct Uses: Targeting Advanced Prostate Cancer\nEnzalutamide 160mg primarily treats metastatic castration-resistant prostate cancer (mCRPC) post-chemotherapy or in pre-chemo settings, where tumors grow despite low testosterone. It excels in non-metastatic CRPC (nmCRPC) by delaying metastasis onset, with trials showing median metastasis-free survival exceeding 3 years versus placebo. In mCSPC, combination with ADT prolongs overall survival by months, reducing radiographic progression risks.​\n\nClinicians prescribe it for high-risk patients with rising PSA despite androgen deprivation therapy (ADT), as it shrinks tumors, alleviates bone pain from metastases, and improves quality of life metrics like urinary function and fatigue scores. Regular monitoring via PSA doubling time and imaging guides ongoing use.​\n\nKey Benefits of Enzalutamide 160mg\nEnzalutamide 160mg delivers transformative outcomes through potent androgen blockade:\n\nExtended Progression-Free Survival: PROSPER trial data indicate 97% risk reduction in metastasis or death for nmCRPC; ENZAMET shows 33% overall survival benefit in mCSPC.​\n\nPSA Response Rates: Over 78% achieve ≥50% PSA decline in mCRPC, correlating with radiographic stability and symptom palliation.​\n\nBone Metastasis Control: Lowers skeletal-related events by 30-40%, preserving mobility and reducing fracture incidence when paired with bone agents.​\n\nQuality of Life Preservation: FACT-P scores improve in pain, appetite, and emotional well-being domains, enabling patients to maintain daily activities longer.​\n\nOral Convenience: Once-daily dosing without food restrictions enhances adherence compared to infusions or multi-pill regimens.​\n\nThese advantages position enzalutamide 160mg as a cornerstone in modern prostate cancer protocols, particularly for fit patients tolerating its profile.​\n\nSide Effects: Managing Risks Effectively\nWhile effective, enzalutamide 160mg carries side effects from androgen suppression and receptor antagonism, affecting 70-90% of users to varying degrees. Most prove manageable with supportive care, dose holds, or adjustments, but vigilance remains essential.​\n\nCommon Side Effects\nFrequently reported (≥10%) issues include:\n\nFatigue/Asthenia (30-40%): Profound tiredness impacting daily tasks; rest, exercise, and stimulants like modafinil help.​\n\nHot Flashes (20-25%): Sudden heat waves; cooling strategies and SSRIs alleviate symptoms.​\n\nMusculoskeletal Pain (15-30%): Joint/muscle aches; NSAIDs or physical therapy provide relief.​\n\nDiarrhea/Constipation (10-20%): Alternating bowel changes; fiber, hydration, and laxatives balance gut function.​\n\nHypertension (10-15%): Blood pressure elevations; routine monitoring and antihypertensives control spikes.​\n\nThese transient effects often peak in first months, diminishing with acclimation.​\n\nSerious Side Effects\nSeek immediate care for:\n\nSeizures (1-2%): Risk higher with brain history; anticonvulsants or discontinuation advised.​\n\nFalls/Fractures (10-15%): Due to weakness, dizziness; fall precautions and bone density scans mitigate.​\n\nCardiovascular Events: Myocardial infarction, strokes (2-5%); lipid/BP checks essential.​\n\nPosterior Reversible Encephalopathy Syndrome (PRES): Rare confusion, seizures, vision loss; MRI confirms.​\n\nSevere Skin Reactions: Stevens-Johnson syndrome; rash monitoring critical.​\n\nBaseline neurological assessments and quarterly labs optimize safety.​\n\nDosage and Administration Guidelines\nSwallow four 40mg capsules whole once daily at the same time, with or without food, totaling 160mg. No dose reductions below 120mg recommended; hold for grade 3-4 toxicity, resuming at prior dose once resolved. Hepatic impairment (Child-Pugh B/C) warrants caution; renal adjustments unnecessary. Continue indefinitely unless progression or intolerance occurs.​\n\nPrecautions and Monitoring\nAvoid in seizure history without prophylaxis; women (especially pregnant) must not handle due to teratogenicity. Strong CYP2A4 inducers/inhibitors alter exposure—adjust accordingly. Elderly patients face amplified fall risks; annual DEXA scans track bone health. Regular PSA, testosterone, CBC, liver enzymes, and ECGs ensure proactive management.​\n\nConclusion\nEnzalutamide 160mg stands as a pivotal advancement in prostate cancer care, offering substantial delays in disease progression, symptom control, and survival gains for patients facing hormone-resistant stages. By meticulously balancing its robust benefits against manageable side effects through vigilant monitoring and supportive measures, individuals regain control over their health journey. Consult oncologists to integrate this therapy seamlessly, tailoring it to personal profiles for optimal, life-extending results\nEmail: info@sterispharma.com / contact@sterispharma.com\nCall/WhatsApp: 7877551268, 7849827488\n\n\n\n\n\n\n\n", "price": 5531.0, "discountamount": 1660.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "Call", "Email", "mCRPC", "growth", "doctor", "Dosage", "action", "fatigue", "product", "WhatsApp", "patients", "androgens", "ENZULAMIDE", "hot flashes", "information", "Enzalutamide", "sterisonline", "sterispharma", "cancer cells", "hypertension", "male hormones", "administration", "health condition", "Common side effects", "comprehensive advice", "healthcare professional", "potent anti-androgen medication", "metastatic castration-resistant prostate cancer" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1528, "imageuri": "https://productimages.withfloats.com/actual/667d2980c303c6d6ad1360bf.png", "tileimageuri": "https://productimages.withfloats.com/tile/667d2980c303c6d6ad1360bf.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-07T10:45:51.202Z", "updatedon": "2025-12-03T11:28:49.659Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/enzalutamide-160-mg-tablet/1528", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "ENZULAMIDE 160", "category": "Oncology", "tags": [ "enzalutamide 160 mg price in india", "enzalutamide 160 mg uses", "", "enzalutamide 160 mg side effects", "prostate cancer", "prostate tumors of growth signals", "metastatic castration-resistant prostate cancer" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6943af86161ad9de85f42b10", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Imatinib IP 400mg", "description": "IMATIFLOW 400, containing Imatinib IP 400mg, represents a breakthrough in targeted cancer therapy, offering patients a precise weapon against specific malignancies. This oral medication belongs to the class of tyrosine kinase inhibitors, revolutionizing treatment for conditions once deemed challenging to manage. By blocking abnormal proteins that fuel cancer cell growth, IMATIFLOW 400 helps restore normal cellular function and improves quality of life for many users.​\n\nProduct Overview\nIMATIFLOW 400 is a branded formulation of Imatinib mesylate 400mg, produced to high pharmaceutical standards for consistent efficacy and bioavailability. Each tablet delivers the active ingredient in a film-coated form, designed for once-daily administration with food to enhance absorption and minimize gastrointestinal upset. Developed for adult patients, it targets cancers driven by dysregulated tyrosine kinases like BCR-ABL, c-KIT, and PDGFR, making it a cornerstone in modern oncology protocols.​\n\nThe medication's mechanism hinges on competitive inhibition at the ATP-binding site of these kinases, halting downstream signaling pathways that promote uncontrolled proliferation, survival, and metastasis of malignant cells. Unlike traditional chemotherapy, which broadly attacks dividing cells, IMATIFLOW 400 spares most healthy tissues, leading to a more favorable safety profile. Clinical data from pivotal trials underscore its role as first-line therapy, with high response rates observed within months of initiation.​\n\nPrimary Uses\nIMATIFLOW 400 excels in treating chronic myeloid leukemia (CML), particularly in the chronic phase where it induces deep molecular responses in over 80% of patients. It suppresses the Philadelphia chromosome-positive cells hallmark of CML by inhibiting the BCR-ABL fusion protein, dramatically extending progression-free survival. For newly diagnosed patients, standard dosing starts at 400mg daily, often achieving complete cytogenetic remission.​\n\nIn gastrointestinal stromal tumors (GIST), IMATIFLOW 400 targets KIT or PDGFRA mutations, shrinking unresectable tumors and delaying progression in advanced cases. The recommended dose remains 400mg once daily, with potential escalation to 600-800mg for resistant strains, as per oncology guidelines. It also finds application in dermatofibrosarcoma protuberans (DFSP), aggressive systemic mastocytosis, and certain myelodysplastic syndromes, broadening its utility in precision medicine.​\n\nHealthcare providers monitor response via PCR for BCR-ABL transcripts in CML or imaging for GIST, adjusting therapy based on milestones like major molecular response. Patients with Ph+ acute lymphoblastic leukemia (ALL) may receive it adjunctively, enhancing outcomes when combined with chemotherapy. Overall, IMATIFLOW 400 transforms these diseases from fatal to chronically manageable.​\n\nKey Benefits\nOne standout benefit of IMATIFLOW 400 is its oral convenience, eliminating the need for frequent hospital visits associated with infusions. Response rates exceed 90% in early CML, with many patients achieving treatment-free remission after sustained deep responses, a paradigm shift from interferon-era therapies.​\n\nTumor control in GIST prevents life-threatening complications like bowel obstruction, improving survival from months to years. Its specificity reduces severe toxicities, allowing patients to maintain daily activities, work, and social engagements with minimal disruption. Long-term studies report 10-year survival rates above 80% in CML, underscoring durable efficacy.​\n\nAdditional advantages include cost-effectiveness over biologics and compatibility with supportive care like hydroxyurea for cytoreduction. Fluid retention, while common, responds well to diuretics, preserving cardiac function. For Indian patients, accessible pricing via brands like IMATIFLOW 400 supports equitable care in resource-limited settings.​\n\nPotential Side Effects\nWhile generally well-tolerated, IMATIFLOW 400 can cause edema (swelling in legs or face) in up to 70% of users, managed by dose reduction or supportive measures. Gastrointestinal issues like nausea, vomiting, and diarrhea affect 40-50%, often resolving with antiemetics and dietary adjustments.​\n\nMusculoskeletal pain, cramps, and fatigue occur frequently, alongside rash and abdominal discomfort. Hematologic effects include neutropenia or thrombocytopenia, necessitating regular blood counts. Rare but serious risks involve liver enzyme elevation, heart failure, or hemorrhage; prompt reporting of symptoms like shortness of breath or yellowing skin is crucial.​\n\nAvoid grapefruit juice, as it elevates drug levels, and inform doctors of concurrent medications like CYP3A4 inhibitors. Pregnancy category D status advises contraception, with monitoring for growth retardation in exposed fetuses. Dizziness may impair driving, so caution is essential during initial weeks.​\n\nDosage and Administration Guidelines\nSwallow IMATIFLOW 400 whole with a meal and full glass of water to optimize pharmacokinetics and reduce esophageal irritation. The standard adult dose for CML chronic phase is 400mg daily; for accelerated phase or blast crisis, 600mg. GIST dosing mirrors 400mg, titrated based on tolerance and response.​\n\nRenal or hepatic impairment requires dose adjustments—reduce to 300-400mg in moderate cases. Do not crush or chew tablets. Missed doses should be taken promptly unless near the next, avoiding doubles. Long-term use demands quarterly monitoring of CBC, liver function, and ECG.​\n\nPrecautions and Interactions\nPatients with a cardiac history need baseline echocardiograms, as QT prolongation or effusion risks exist. Drug interactions abound: St. John's wort induces metabolism, reducing efficacy; ketoconazole boosts levels. Vaccines, especially live ones, are contraindicated during therapy.​\n\nRegular dermatologic checks mitigate skin cancer risk from prolonged use. Hydration combats fluid retention, and low-salt diets aid management. Steris Healthcare emphasizes patient education via counseling on adherence for optimal outcomes.​\n\nConclusion\nIMATIFLOW 400 (Imatinib IP 400mg) stands as a testament to targeted therapy's power, offering robust control over CML, GIST, and related cancers with a balance of efficacy and manageability. Its benefits in prolonging life and enhancing daily functioning far outweigh transient side effects for most when monitored diligently. Consult oncologists for personalized plans, ensuring this innovative treatment maximizes hope and health in the fight against cancer.", "price": 1827.0, "discountamount": 540.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2249, "imageuri": "https://productimages.withfloats.com/actual/6943b026ca1b0dcfc6c37820.png", "tileimageuri": "https://productimages.withfloats.com/tile/6943b026ca1b0dcfc6c37820.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-18T07:38:46.766Z", "updatedon": "2025-12-18T07:41:25.851Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/imatinib-ip-400mg/2249", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "IMATIFLOW 400", "category": "NEPHROLOGYRANGE", "tags": [ "Imatinib IP 400mg", "offering robust control over CML.", "related cancers with a balance of efficacy and manageability.", "innovative treatment maximizes hope and health in the fight against cancer.", "cancer therapy.", "fuel cancer cell growth.", "chemotherapy." ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6937c92e461b07808ef722e4", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Cyclosporine 100mg", "description": "Cyclosporine, marketed under the brand name CYCLOPURE 100, is a potent immunosuppressant medication widely used in clinical settings to prevent organ transplant rejection and to manage various autoimmune disorders. Available as a 100mg oral capsule, CYCLOPURE 100 plays a critical role in modulating the immune system, helping patients maintain graft survival and control symptoms of immune-related diseases.\n\nProduct Description\nCYCLOPURE 100 contains cyclosporine, a cyclic polypeptide consisting of 11 amino acids, derived from the fungus Tolypocladium inflatum. It selectively inhibits the activity of T-lymphocytes, a subset of white blood cells that play a central role in immune response. By targeting these immune cells, cyclosporine helps prevent the body’s immune system from attacking transplanted organs, such as kidneys, liver, or heart, and reduces inflammation in autoimmune diseases.\n\nThe capsules are formulated for oral administration, with each capsule containing 100mg of cyclosporine. This dosage provides an effective balance between immunosuppression and safety for most adult patients, although dosing must be carefully tailored by healthcare providers based on patient response, therapeutic drug monitoring, and condition severity.\n\nUses of CYCLOPURE 100\nCYCLOPURE 100 is primarily indicated for the following medical purposes:\n\nPrevention of Organ Transplant Rejection: It is commonly prescribed to recipients of kidney, liver, heart, or other organ transplants to prevent acute and chronic rejection by suppressing immune responses that target the graft.\n\nAutoimmune Disease Management: Cyclosporine is effective in treating autoimmune disorders such as rheumatoid arthritis, psoriasis, and certain types of nephrotic syndrome. By reducing immune system overactivity, it helps alleviate symptoms such as joint inflammation, skin lesions, and kidney damage.\n\nSevere Atopic Dermatitis: In cases where conventional treatments are ineffective, cyclosporine may be used to control symptoms of severe eczema by modulating immune hyper-reactivity.\n\nOther Off-Label Uses: Occasionally, cyclosporine is used for other immune-mediated conditions like uveitis, Crohn’s disease, and some forms of lupus nephritis depending on physician discretion.\n\nKey Benefits\nEffective Immunosuppression: CYCLOPURE 100 is known for its potent ability to suppress immune responses selectively, significantly reducing the risk of organ rejection after transplantation and improving graft survival rates.\n\nVersatility in Autoimmune Conditions: Beyond organ transplantation, cyclosporine’s immunomodulatory effects provide relief in autoimmune diseases by controlling inflammation and immune overactivity that cause tissue damage.\n\nImprovement in Quality of Life: By controlling disease symptoms such as joint pain, skin inflammation, or kidney impairment, CYCLOPURE 100 enables patients to experience improved physical comfort and daily functioning.\n\nOral Administration Convenience: The capsule form ensures ease of use and better patient compliance compared to injectable immunosuppressants, allowing therapy to be managed on an outpatient basis.\n\nTherapeutic Drug Monitoring: The availability of blood level monitoring helps customize dosage and maximize therapeutic effects while minimizing toxicity.\n\nSide Effects and Precautions\nWhile CYCLOPURE 100 is highly beneficial, it carries a risk of side effects due to its immunosuppressive nature and systemic effects. Common, less severe side effects include:\n\nGingival hyperplasia (gum overgrowth)\n\nTremors or mild neurological symptoms\n\nHypertension (high blood pressure)\n\nIncreased hair growth (hypertrichosis)\n\nGastrointestinal disturbances (nausea, diarrhea)\n\nMore serious adverse effects, which require immediate medical attention, can include:\n\nNephrotoxicity: Cyclosporine can affect kidney function; regular monitoring of kidney function tests is essential.\n\nIncreased Risk of Infections: Suppression of the immune system increases vulnerability to bacterial, viral, and fungal infections.\n\nHepatotoxicity: Liver function should be monitored as cyclosporine may cause elevated liver enzymes or more severe liver damage.\n\nMalignancies: Long-term use has been associated with an increased risk of certain cancers, particularly lymphomas and skin cancers.\n\nElectrolyte Imbalances: Hypomagnesemia and hyperkalemia are possible and require monitoring.\n\nPatients must inform their healthcare providers about other medications they take, as cyclosporine has significant drug interactions that can affect its blood levels and toxicity risk, including with antibiotics, antifungals, anticonvulsants, and others.\n\nConclusion\nCYCLOPURE 100 (Cyclosporine 100mg) stands as a cornerstone immunosuppressant medication that plays a vital role in preventing organ rejection and managing autoimmune diseases. Its targeted immunosuppressive action effectively reduces disease burden, enhances graft survival, and improves patients’ quality of life. Although it entails risks of side effects, careful medical supervision, therapeutic drug monitoring, and adherence to prescribed dosing protocols effectively mitigate these concerns.\n\nFor patients undergoing organ transplantation or those with autoimmune conditions unresponsive to standard therapies, CYCLOPURE 100 provides a valuable therapeutic solution. Always consult a healthcare professional before starting or adjusting therapy with CYCLOPURE 100 to ensure the safest and most effective use tailored to individual clinical needs.", "price": 1014.0, "discountamount": 305.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2239, "imageuri": "https://productimages.withfloats.com/actual/6937c930ed26b2c06ce34f7e.jpeg", "tileimageuri": "https://productimages.withfloats.com/tile/6937c930ed26b2c06ce34f7e.jpeg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-09T07:01:02.399Z", "updatedon": "2025-12-09T07:01:02.399Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/cyclosporine-100mg/2239", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CYCLOPURE 100", "category": "NEUROLOGY RANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69316145bf2a5ce08905eadf", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Temozolomide 250 mg", "description": "Temozolomide 250 mg, marketed under the brand name TMOZOLMIDE 250 by Steris Healthcare, is a potent chemotherapy drug primarily used to treat certain aggressive brain tumors such as glioblastoma multiforme (GBM) and anaplastic astrocytoma. Its mechanism of action involves alkylation of DNA, which damages the cancer cells’ DNA strands, leading to their programmed death and inhibition of tumor growth. This effect is achieved through the addition of a methyl group at the O6 and N7 positions of guanine in DNA. Tumor cells damaged by this process are unable to reproduce and eventually die, making Temozolomide an effective agent in chemotherapy regimens[,].​\n\nWhat are the Benefits of Temozolomide 250 mg?\nTemozolomide 250 mg offers significant benefits for patients battling brain cancers. It crosses the blood-brain barrier effectively, which allows it to reach tumor cells inside the brain where many other drugs cannot penetrate. This expands its efficacy in treating primary brain tumors and certain metastatic tumors that have spread to the brain. In clinical settings, it has been shown to improve progression-free survival rates and, in some cases, overall survival when used with radiation therapy or alone during maintenance treatment phases[,].​\n\nKey Benefits of Temozolomide 250 mg\nEffective treatment of aggressive brain tumors like glioblastoma multiforme and anaplastic astrocytoma.\n\nCan be administered orally, offering convenience compared to intravenous chemotherapy.\n\nAbility to cross the blood-brain barrier ensuring targeted therapy within the central nervous system.\n\nWell-established as part of the standard Stupp protocol (combined with radiotherapy).\n\nMay improve quality of life by slowing tumor progression and managing symptoms associated with brain tumors[,].​\n\nSide Effects of Temozolomide 250 mg\nWhile Temozolomide is effective, it may cause side effects common to chemotherapy medications due to its impact on both cancerous and healthy rapidly dividing cells.\n\nCommon Side Effects of Temozolomide 250 mg\nNausea and vomiting, which can sometimes be severe.\n\nFatigue and weakness.\n\nHair thinning or hair loss.\n\nConstipation or diarrhea.\n\nLoss of appetite.\n\nMouth sores or changes in taste.\n\nDizziness or headache.\n\nMild skin rashes or itching[,].​\n\nSerious Side Effects of Temozolomide 250 mg\nSignificant reduction in blood cell counts causing anemia, leukopenia, or thrombocytopenia (requiring close blood monitoring).\n\nSevere infections due to immune suppression.\n\nAllergic reactions including swelling, itching, or rash.\n\nLiver dysfunction or jaundice.\n\nSeizures or neurological symptoms.\n\nUnusual bleeding or bruising.\n\nSigns of severe allergic reaction like difficulty breathing[,].​\n\nAvailable Substitute for Temozolomide 250 mg\nThere are limited direct substitutes for Temozolomide due to its unique ability to treat brain tumors crossing the blood-brain barrier. Alternatives depend on tumor type and may include other chemotherapy drugs like lomustine (CCNU), carmustine (BCNU), or newer targeted therapies and immunotherapies under clinical trial. However, these alternatives may vary in efficacy and side effect profile and are generally used under oncologist guidance[,].\n\nDosage Guidelines for Temozolomide 250 mg\nThe dosage of Temozolomide 250 mg (TMOZOLMIDE 250) by Steris Healthcare is carefully tailored based on the type and stage of cancer, body surface area (BSA), and patient tolerance. The standard regimen for newly diagnosed glioblastoma is an oral dose of 75 mg/m² daily during radiotherapy, followed by maintenance cycles of 150 to 200 mg/m² for 5 days every 28 days. Dose adjustments are common based on blood counts and side effects. Strict adherence to the prescribed dosage schedule and monitoring are critical for safety and efficacy.", "price": 12187.0, "discountamount": 3657.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2229, "imageuri": "https://productimages.withfloats.com/actual/693161477743cf6a1359d094.jpg", "tileimageuri": "https://productimages.withfloats.com/tile/693161477743cf6a1359d094.jpg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-04T10:24:05.165Z", "updatedon": "2025-12-17T08:31:12.254Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/temozolomide-250-mg/2229", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "TMOZOLMIDE 250", "category": "Oncology", "tags": [ "Temozolomide 250 mg", "cancer", "brain tumors", "cancer cells", "Tumor cells", "chemotherapy", "TMOZOLMIDE 250" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6916c002d152b8cabef859ea", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Miltefosine Capsules", "description": "Miltefosine Capsules are an important oral medication widely recognized for their effectiveness in treating Visceral Leishmaniasis (Kala-azar), Cutaneous Leishmaniasis, and certain protozoal infections. As the first and only oral drug approved for the treatment of Leishmaniasis, Miltefosine has significantly transformed patient care by offering a convenient and reliable alternative to painful injectable therapies. The medication belongs to the class of alkylphosphocholine drugs and is known for its potent antiparasitic and cytotoxic actions.\n\nMiltefosine Capsules are typically prescribed by healthcare professionals when a confirmed diagnosis of Leishmaniasis has been made, or when the patient is not responding adequately to other modes of therapy. Its high absorption rate, ease of administration, and consistent therapeutic activity make it a cornerstone in parasitic infection management across endemic regions.\n\nWhat Are Miltefosine Capsules?\n\nMiltefosine is an oral antiparasitic medication designed to eliminate Leishmania parasites by disrupting their cell membranes and metabolic functions. It was originally studied for anticancer activities but later found to be highly effective against various Leishmania species. Unlike conventional treatment options that require hospitalization and injections, Miltefosine offers a non-invasive, at-home oral therapy option, improving both patient comfort and compliance.\n\nMiltefosine Capsules are generally marketed in different strengths such as 50 mg. The duration of treatment usually ranges between 28–30 days depending on the medical condition and severity.\n\nUses of Miltefosine Capsules\n\nMiltefosine Capsules are primarily prescribed for:\n\n1. Visceral Leishmaniasis (Kala-azar)\n\nThis is a severe, life-threatening parasitic disease affecting internal organs such as the spleen, liver, and bone marrow. Miltefosine is considered one of the most effective oral treatment options for Kala-azar and is widely used in India and other tropical regions where the disease is endemic.\n\n2. Cutaneous Leishmaniasis\n\nIt causes skin lesions, ulcers, and disfiguring scars. Miltefosine works by targeting the parasite in skin tissues, promoting faster healing and reducing complications.\n\n3. Mucocutaneous Leishmaniasis\n\nThough less common, this form affects mucous membranes of the nose, mouth, and throat. Miltefosine plays a major role in preventing progressive tissue destruction.\n\n4. Off-Label Uses\n\nIn some cases, doctors may prescribe Miltefosine for:\n\nCertain protozoal infections\n\nAmoebic keratitis (rare condition affecting the eye)\n\nParasitic infections resistant to other treatments\n\nHowever, these uses should only be followed under strict medical supervision.\n\nHow Miltefosine Works\n\nMiltefosine acts directly on parasitic cells by:\n\nDisrupting cell membrane integrity\n\nInterfering with phospholipid metabolism\n\nTriggering apoptosis-like cell death in parasites\n\nWeakening parasite reproduction and survival\n\nThis multi-target mechanism makes Miltefosine one of the most powerful oral antiparasitic medications available today.\n\nKey Benefits of Miltefosine Capsules\n1. Highly Effective Oral Treatment\n\nUnlike older treatments requiring multiple injections, Miltefosine provides a simple oral dosage, eliminating the need for hospitalization or painful procedures.\n\n2. Excellent Patient Compliance\n\nThe convenience of taking capsules at home significantly improves adherence to treatment, especially in rural or resource-limited areas.\n\n3. Strong Activity Against Leishmania Species\n\nMiltefosine’s broad-spectrum antiparasitic properties make it effective against several strains of Leishmania responsible for different clinical presentations of the disease.\n\n4. Lower Risk of Severe Treatment Complications\n\nCompared to traditional injectable therapies like antimonials, Miltefosine has a better safety profile when used under medical supervision.\n\n5. Reduces Disease Transmission\n\nBy effectively eliminating parasites from the body, Miltefosine helps reduce the overall disease burden in endemic communities.\n\n6. Faster Healing of Skin Lesions\n\nPatients with Cutaneous Leishmaniasis experience faster recovery, reduced lesion size, and minimal scarring when treatment is taken on time.\n\n7. Well-Studied and Recommended\n\nMiltefosine is recommended by WHO and national health authorities in many countries as a frontline treatment for Kala-azar.\n\nPossible Side Effects of Miltefosine Capsules\n\nWhile generally well tolerated, Miltefosine may cause certain side effects. Most of these are mild to moderate and subside as the body adapts to the medication.\n\nCommon Side Effects\n\nNausea and vomiting\n\nDiarrhea\n\nAbdominal discomfort\n\nLoss of appetite\n\nTemporary weakness or fatigue\n\nModerate Side Effects\n\nElevated liver enzymes\n\nMild kidney function changes\n\nSkin reactions such as redness or itching\n\nSevere, But Less Common Side Effects\n\nNephrotoxicity (kidney-related issues)\n\nHepatotoxicity (liver-related issues)\n\nSevere gastrointestinal upset\n\nVision-related disturbances in very rare cases\n\nImportant Warning for Women\n\nMiltefosine is NOT recommended during pregnancy as it can cause fetal harm. Women of childbearing age must use reliable contraception during treatment and for at least 3 months after therapy.\n\nPrecautions\n\nPatients with the following conditions should use Miltefosine cautiously:\n\nLiver or kidney disease\n\nPregnancy or breastfeeding\nSevere dehydration\nUncontrolled vomiting or diarrhea\n\nAlways follow the dosage exactly as prescribed by a healthcare professional.\n\nConclusion\n\nMiltefosine Capsules have revolutionized the treatment of various forms of Leishmaniasis by offering a powerful, effective, and convenient oral therapy option. Their ability to target parasitic infections through multiple mechanisms makes them a trusted solution in endemic regions. Whether used for Visceral, Cutaneous, or Mucocutaneous Leishmaniasis, Miltefosine provides significant therapeutic benefits, faster recovery, and improved patient compliance.", "price": 1350.0, "discountamount": 405.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2205, "imageuri": "https://productimages.withfloats.com/actual/6916c0042444cd45b3f0f253.png", "tileimageuri": "https://productimages.withfloats.com/tile/6916c0042444cd45b3f0f253.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-14T05:37:06.048Z", "updatedon": "2025-12-09T05:59:01.077Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/miltefosine-capsules/2205", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MILTEFOSE 50", "category": "GENERAL RANGE", "tags": [ "Miltefosine Capsules", "Visceral Leishmaniasis (Kala-azar)", "protozoal infections", "Cutaneous Leishmaniasis" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6891f29bfb7044dfb2d43adf", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "megestrol acetate 160 mg", "description": "MAGRAL 160 is a pharmaceutical medication containing megestrol acetate 160 mg, a synthetic progestin known for its potent antineoplastic and appetite-stimulating properties. This drug is primarily prescribed to manage significant health challenges such as unexplained weight loss, anorexia, and cachexia, especially in patients suffering from chronic conditions like cancer or AIDS. Additionally, megestrol acetate functions as a hormone therapy agent employed in the treatment of certain hormone-sensitive malignancies. Its dual action both supports tumor management and improves patients' nutritional status by stimulating appetite and promoting weight gain, thereby enhancing overall quality of life. The drug is regarded as a crucial option in oncology and palliative care for managing complex conditions related to hormone-dependent cancers and severe wasting syndromes.\n\nWhat is MAGRAL 160?\nMAGRAL 160 is an oral medication formulated with megestrol acetate 160 mg, a synthetic progestin hormone derivative. It works primarily by modulating hormone receptors and altering hormone levels that influence the growth of hormone-responsive tumors such as breast and endometrial cancers. Apart from its antineoplastic action, it stimulates appetite by acting on the hypothalamic centers responsible for hunger, helping patients suffering from severe weight loss regain a healthy appetite and weight.\nUses of MAGRAL 160\nTo treat hormone-dependent cancers, specifically advanced breast cancer and endometrial cancer.\nTo stimulate appetite and promote weight gain in patients experiencing anorexia, cachexia, or unexplained severe weight loss related to chronic illnesses like cancer or AIDS.\n\nTo manage wasting syndromes that lead to malnutrition and significant weight loss.\n\nTo serve as an antineoplastic agent in hormone-sensitive malignancies.\n\nIn short, MAGRAL 160 is primarily used to treat anorexia and cachexia or serious unexplained weight loss and is also used as an antineoplastic agent to treat certain types of malignancy.\n\nSide Effects of MAGRAL 160\n\nWeight gain (often desirable but can be excessive)\n\nFluid retention and edema (swelling)\n\nNausea and vomiting\n\nDiarrhea or constipation\n\nVaginal bleeding or spotting in women\n\nFatigue, weakness, and insomnia\n\nHeadache and dizziness\n\nIncreased risk of blood clots (deep vein thrombosis or pulmonary embolism)\n\nHormonal imbalances, such as decreased sex hormone levels, which can lead to sexual dysfunction or bone density loss\n\nAllergic reactions including rash or itching\n\nPatients should report severe or unusual symptoms, especially signs of blood clots such as limb swelling, chest pain, or sudden shortness of breath, immediately to their healthcare provider.\n\nPrecautions before Using MAGRAL 160\n\nInform your doctor if you are pregnant, breastfeeding, or planning to conceive as MAGRAL 160 is contraindicated in pregnancy.\n\nDisclose any history of blood clots, cardiovascular diseases, liver or kidney impairment.\n\nPatients with diabetes should monitor blood sugar closely as megestrol acetate may cause hyperglycemia.\n\nAvoid sudden discontinuation without medical advice to prevent potential hormonal withdrawal effects.\n\nRegular monitoring is required, including hormone levels and blood tests, to assess efficacy and safety during treatment.\n\nUse cautiously in patients at risk for deep vein thrombosis or pulmonary embolism due to increased clotting risks.\n\nDrug Interactions: What Drugs Interact with MAGRAL 160?\n\nCYP3A4 enzyme inducers (e.g., rifampin, phenytoin) may reduce the effectiveness of megestrol acetate by increasing its metabolism.\n\nConcurrent use with blood thinners (anticoagulants) requires careful monitoring as MAGRAL 160 might influence clotting parameters.\n\nCombining with drugs that affect hormonal pathways, such as other hormonal therapies or corticosteroids, may alter treatment outcomes.\n\nInteractions with diabetes medications might necessitate dose adjustment due to potential effects on blood sugar control.\n\nCareful medical supervision is necessary when used with immunosuppressants or other chemotherapy agents to avoid additive side effects or altered drug levels.\n\nConclusion\nMAGRAL 160, containing megestrol acetate 160 mg, is a clinically validated medication widely used to manage complex conditions such as hormone-dependent cancers as well as severe weight loss due to anorexia and cachexia. Its unique ability to act both as an antineoplastic agent and an appetite stimulant makes it invaluable in improving patient outcomes, nutritional status, and overall quality of life. Patients prescribed MAGRAL 160 should adhere strictly to their healthcare provider’s instructions and report any adverse effects promptly. This medication should always be used under medical supervision to ensure optimal benefits and minimize risks.", "price": 759.0, "discountamount": 228.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2156, "imageuri": "https://productimages.withfloats.com/actual/6891f2a0115b51057b971998.png", "tileimageuri": "https://productimages.withfloats.com/tile/6891f2a0115b51057b971998.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-08-05T12:01:31.195Z", "updatedon": "2025-12-02T06:52:57.983Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/megestrol-acetate-160-mg/2156", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MAGRAL 160", "category": "Gynaecology", "tags": [ "megestrol acetate 160 mg", "cancer or AIDS", "hormone derivative", "sex hormone levels" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "68832b7f217a4e897b4812dd", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "ranitidine dicyclomine hydrochloride and simethicone tablets", "description": "SMITHCON ACID TABLETS is a scientifically formulated oral medication designed to offer comprehensive relief from gastrointestinal disturbances such as acidity, gas, bloating, indigestion, and abdominal cramps. This tablet combines three powerful ingredients: Dicyclomine Hydrochloride 10 mg, Simethicone 20 mg, and Ranitidine Hydrochloride 150 mg. Together, these compounds address various symptoms of digestive distress and provide fast, effective, and lasting comfort.\n\nWhat is SMITHCON ACID TABLETS?\nSMITHCON ACID TABLETS is a combination medication containing three active ingredients:\n\nDicyclomine Hydrochloride 10 mg – An antispasmodic agent that works by relaxing the smooth muscles of the stomach and intestines, helping relieve painful cramps, spasms, and abdominal discomfort.\n\nSimethicone 20 mg – An anti-foaming agent that breaks down gas bubbles in the stomach and intestines, providing quick relief from bloating, fullness, and abdominal pressure.\n\nRanitidine Hydrochloride 150 mg – A histamine-2 (H2) receptor blocker that reduces the production of stomach acid, effectively treating heartburn, acid reflux, and indigestion.\n\nUses of SMITHCON ACID TABLETS:\nSMITHCON ACID TABLETS is used to treat a variety of gastrointestinal conditions, including:\n\nAcid indigestion and heartburn\n\nGastroesophageal reflux disease (GERD)\n\nFlatulence and bloating\n\nAbdominal cramps and spasms\n\nIrritable bowel syndrome (IBS)\n\nFunctional dyspepsia\n\nExcessive stomach acid production\n\nThe triple-action mechanism provides targeted relief from gas, acidity, and muscle spasms, making SMITHCON ACID TABLETS an ideal choice for patients experiencing multiple digestive complaints.\n\nSide Effects of SMITHCON ACID TABLETS:\nWhile generally well-tolerated, some patients may experience side effects such as:\n\nDry mouth\n\nDizziness or light-headedness\n\nNausea or constipation\n\nBlurred vision\n\nDrowsiness\n\nAllergic reactions (rare)\n\nHeadache or mild abdominal discomfort\n\nIf any of these symptoms persist or worsen, it is advised to consult a healthcare professional.\n\nPrecautions Before Using SMITHCON ACID TABLETS:\nBefore starting SMITHCON ACID TABLETS, inform your doctor if you have:\n\nGlaucoma\n\nEnlarged prostate\n\nObstructive gastrointestinal conditions\n\nLiver or kidney disease\n\nHeart conditions\n\nPregnancy or breastfeeding\n\nAvoid alcohol and activities requiring mental alertness if you experience drowsiness or dizziness while taking this medication.\n\nDrug Interactions: What Drugs Interact With SMITHCON ACID TABLETS?\nThe following medications may interact with SMITHCON ACID TABLETS:\n\nAnticholinergic drugs (may enhance side effects of dicyclomine)\n\nAntacids or sucralfate (may interfere with ranitidine absorption)\n\nKetoconazole, itraconazole (reduced absorption due to ranitidine)\n\nCNS depressants like alcohol, sedatives (increased risk of drowsiness)\n\nDigoxin or blood thinners (may be affected by changes in stomach acid levels)\n\nAlways inform your healthcare provider about all medications and supplements you are taking to avoid potential interactions.\n\nParaphrased Clinical Note:\nRanitidine, dicyclomine hydrochloride, and simethicone tablets are a combination medication used to treat various gastrointestinal issues. Ranitidine is an H2 blocker that reduces stomach acid production, helping with heartburn and indigestion. Dicyclomine is an antispasmodic that relaxes stomach and intestinal muscles, relieving cramps and pain. Simethicone helps to relieve gas and bloating by breaking down gas bubbles.\n\nConclusion:\nSMITHCON ACID TABLETS offers a dependable solution for those suffering from common gastrointestinal complaints such as acidity, gas, and abdominal pain. With its triple-action blend of dicyclomine hydrochloride 10mg, simethicone 20 mg, and ranitidine hydrochloride 150 mg, it provides swift and targeted relief for a better quality of life. Consult your physician before use and follow dosage guidelines to maximize its benefits.", "price": 70.0, "discountamount": 21.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2152, "imageuri": "https://productimages.withfloats.com/actual/68832b83093884639e4d0879.png", "tileimageuri": "https://productimages.withfloats.com/tile/68832b83093884639e4d0879.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-07-25T07:00:15.779Z", "updatedon": "2025-12-10T06:15:51.382Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/ranitidine-dicyclomine-hydrochloride-and-simethicone-tablets/2152", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "SMITHCON ACID TABLETS", "category": "GASTROLOGYRANGE", "tags": [ "dicyclomine hydrochloride and simethicone tablets" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "686e5df44c01bda1661052f0", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "ALFUGEM T 2.5/10", "description": "ALFUGEM T 2.5/10 is a scientifically formulated dual-action oral tablet that combines Alfuzosin 2.5 mg and Tadalafil 10 mg. This unique combination is primarily used for the treatment of benign prostatic hyperplasia (BPH) and erectile dysfunction (ED) in men. By blending a selective alpha-blocker (Alfuzosin) with a phosphodiesterase-5 (PDE5) inhibitor (Tadalafil), ALFUGEM T 2.5/10 offers an effective solution for patients who suffer from both urological conditions.\n\nThe combination of alfuzosin and tadalafil has been shown to have an additive relaxant effect on human detrusor and prostatic tissues in vitro, enhancing urinary flow and improving sexual function.\n\nWhat is ALFUGEM T 2.5/10?\nALFUGEM T 2.5/10 is a fixed-dose combination tablet that contains two active ingredients:\n\nAlfuzosin (2.5 mg) – an alpha-1 adrenergic receptor blocker that relaxes the muscles in the prostate and bladder neck.\n\nTadalafil (10 mg) – a PDE5 inhibitor that increases blood flow to the penis and also helps relax the smooth muscles in the prostate and bladder.\n\nTogether, they help relieve lower urinary tract symptoms (LUTS) associated with BPH and improve erectile function in men.\n\nUses of ALFUGEM T 2.5/10:\nTreatment of Benign Prostatic Hyperplasia (BPH)\n\nRelief of lower urinary tract symptoms (LUTS) such as weak stream, urgency, and incomplete bladder emptying\n\nManagement of erectile dysfunction (ED) in men\n\nMay be beneficial for patients with both BPH and ED as a once-daily treatment\n\nHow Does ALFUGEM T 2.5/10 Work?\nAlfuzosin works by blocking alpha-1 receptors in the prostate and bladder, leading to relaxation of smooth muscle and improved urine flow.\n\nTadalafil enhances nitric oxide activity, leading to vasodilation in the penile tissues and also relaxes the lower urinary tract muscles.\n\nThe additive relaxant effect of this combination on the prostate and bladder tissues helps improve both urinary and sexual symptoms.\n\nSide Effects of ALFUGEM T 2.5/10:\nLike all medications, ALFUGEM T 2.5/10 may cause some side effects. Common side effects include:\n\nDizziness or lightheadedness\n\nHeadache\n\nBack pain or muscle aches\n\nNasal congestion\n\nIndigestion\n\nFlushing\n\nLow blood pressure (hypotension) in some cases\n\nRare but serious side effects may include:\n\nFainting or severe dizziness\n\nPriapism (prolonged or painful erection)\n\nVision changes or sudden vision loss\n\nChest pain or irregular heartbeat\n\nPrecautions Before Using ALFUGEM T 2.5/10:\nConsult your doctor before use if you have a history of heart disease, liver/kidney problems, or hypotension.\n\nAvoid activities like driving or operating machinery if you feel dizzy after taking the tablet.\n\nDo not take with other PDE5 inhibitors or alpha-blockers unless prescribed.\n\nLimit alcohol intake, as it can increase the risk of dizziness or low blood pressure.\n\nNot recommended for use in women or children.\n\nDrug Interactions – What Drugs Interact with ALFUGEM T 2.5/10?\nCertain drugs may interact with ALFUGEM T 2.5/10 and affect its effectiveness or increase the risk of side effects:\n\nAvoid or use with caution:\n\nNitrates (e.g., nitroglycerin) – can cause dangerous drops in blood pressure\n\nOther alpha-blockers – increased risk of hypotension\n\nAntifungals (e.g., ketoconazole, itraconazole)\n\nHIV protease inhibitors (e.g., ritonavir)\n\nAntibiotics (e.g., erythromycin, clarithromycin)\n\nBlood pressure medications – may enhance hypotensive effect\n\nGrapefruit juice – can alter the drug metabolism\n\nAlways inform your doctor about all the medications and supplements you are taking.\n\nConclusion:\nALFUGEM T 2.5/10 offers a comprehensive dual-action approach to managing two common male conditions – BPH and ED. With the clinically proven benefits of alfuzosin and tadalafil, this medication not only improves urinary flow and relieves prostate-related discomfort but also enhances sexual performance. Its synergistic relaxant effect on the bladder, prostate, and penile tissues makes it an ideal solution for men looking for convenience, efficacy, and improved quality of life.\n\nAlways follow your healthcare provider’s instructions for safe and effective use.", "price": 290.0, "discountamount": 87.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2143, "imageuri": "https://productimages.withfloats.com/actual/686e5df9e9241987c803df61.png", "tileimageuri": "https://productimages.withfloats.com/tile/686e5df9e9241987c803df61.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-07-09T12:17:56.999Z", "updatedon": "2025-12-02T07:17:45.264Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/alfugem-t-2-5-10/2143", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "alfuzosin and tadalafil", "category": "UROLOGYRANGE", "tags": [ "alfuzosin and tadalafil", "phosphodiesterase-5", "prostatic hyperplasia (BPH)", "Tadalafil" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "68272992e579986392b124bf", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Nintedanib 150mg", "description": "NINTEPRIDE 150 is a prescription medication that contains Nintedanib 150 mg, a targeted therapy used primarily in the treatment of idiopathic pulmonary fibrosis (IPF), systemic sclerosis-associated interstitial lung disease (SSc-ILD), and certain types of non-small cell lung cancer (NSCLC). It works by slowing the progression of fibrotic diseases, helping to maintain better lung function and improving the patient's quality of life.\n\nKey Ingredient\nNintedanib (150 mg)\nNintedanib is a tyrosine kinase inhibitor that blocks several growth factor receptors responsible for promoting fibrosis and tumor growth. It is an orally administered compound used in chronic and progressive lung conditions.\n\nKey Benefits\nHelps slow down the progression of idiopathic pulmonary fibrosis (IPF).\n\nImproves lung function and delays further decline in lung capacity.\n\nUsed as a treatment for systemic sclerosis-associated interstitial lung disease (SSc-ILD).\n\nBeneficial in certain types of advanced non-small cell lung cancer (NSCLC).\n\nTargets multiple pathways involved in fibrosis and tumor progression.\n\nProvides a convenient oral dosage form for chronic conditions.\n\nHow Does It Work?\nNINTEPRIDE 150 (Nintedanib 150 mg) works by inhibiting multiple receptor tyrosine kinases, including those for platelet-derived growth factor (PDGF), fibroblast growth factor (FGF), and vascular endothelial growth factor (VEGF). These growth factors are responsible for the development and progression of fibrosis and abnormal cell proliferation. By blocking these receptors, Nintedanib helps to:\n\nReduce the formation of scar tissue in the lungs.\n\nDecrease inflammation and tissue remodeling.\n\nInhibit tumor angiogenesis in certain cancer types.\n\nPreserve lung structure and function over time.\n\nDirections for Use\nNINTEPRIDE 150 should be taken orally, twice daily (usually one capsule in the morning and one in the evening).\n\nTake the capsule with food and water to reduce the risk of gastrointestinal side effects.\n\nDo not chew or crush the capsule; swallow it whole.\n\nTake the medication at the same times each day for optimal results.\n\nFollow the dosage and schedule prescribed by your healthcare provider.\n\nIf a dose is missed, skip it and continue with the next scheduled dose. Do not take a double dose.\n\nSide Effects\nNINTEPRIDE 150 may cause some common and serious side effects. It is important to report any persistent or severe symptoms to a healthcare professional.\n\nCommon Side Effects:\n\nDiarrhea\n\nNausea\n\nVomiting\n\nLoss of appetite\n\nWeight loss\n\nAbdominal pain\n\nLiver enzyme elevation\n\nSerious Side Effects:\n\nSevere liver problems\n\nBleeding complications\n\nGastrointestinal perforation\n\nHeart-related issues such as increased blood pressure or myocardial infarction\n\nHypersensitivity reactions including rash, itching, or swelling\n\nRegular liver function monitoring and clinical follow-up are essential while on NINTEPRIDE 150 to ensure safe and effective use.", "price": 987.0, "discountamount": 487.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": [ "nintepride 150", "tumor progression", "capsule swallow", "promoting fibrosis", "nintepride 150nintepride 150", "scheduled dose", "chronic conditions", "lung function", "prescription medication", "ensure safe", "clinical followup", "rash itching", "severe symptoms", "missed skip", "healthcare provider", "schedule prescribed", "time directions", "scar tissue", "growth factors", "lung capacity", "tumor growth", "patients quality", "targeted therapy", "nintedanib 150 mg", "side effects", "gastrointestinal side effects", "orally administered compound", "receptors nintedanib helps", "increased blood pressure", "optimal results follow", "lungs decrease inflammation", "abnormal cell proliferation", "tyrosine kinase inhibitor", "fibrotic diseases helping" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2116, "imageuri": "https://productimages.withfloats.com/actual/682729941972da8c8f537bca.png", "tileimageuri": "https://productimages.withfloats.com/tile/682729941972da8c8f537bca.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-05-16T12:03:30.781Z", "updatedon": "2025-12-02T08:36:59.846Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/nintedanib-150mg/2116", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Steris Healthcare Pvt Ltd", "category": "NEPHROLOGYRANGE", "tags": [ "Nintedanib 150 mg", "Nintedanib 150 mg price in India", "Nintedanib 150 mg brands in India", "Nintedanib 150 mg side effects" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false } ], "hasmoreitems": false, "isapirequest": false, "totalresults": 27, "query": null, "floatingpoint": null }