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"description": "BENZTETRA 25 contains the active ingredient tetrabenazine 25mg, a specialized medication used primarily to manage involuntary movements associated with neurological disorders. Tetrabenazine is classified as a vesicular monoamine transporter 2 (VMAT2) inhibitor and works by regulating the levels of neurotransmitters such as dopamine, serotonin, norepinephrine, and histamine in the brain. This correction of chemical imbalances helps reduce excessive and uncontrolled muscle movements. BENZTETRA 25 is especially valuable for patients suffering from movement disorders that significantly impact their daily functioning. It helps improve motor control, thereby enhancing quality of life for those affected. This medication is prescribed mainly to treat chorea—a movement disorder characterized by jerky, irregular, and uncontrollable muscle movements—that is caused by Huntington disease.\n\nWhat is BENZTETRA 25?\nBENZTETRA 25 is a therapeutic tablet containing tetrabenazine 25mg, designed to treat involuntary movements (chorea) linked to Huntington disease. It does not cure Huntington disease nor address cognitive or psychiatric symptoms of the disease but effectively reduces the severity of abnormal movements by altering neurotransmitter activity in the brain.\n\nUses of BENZTETRA 25\n\nTo treat chorea (a movement disorder) that is caused by Huntington disease.\n\nTo control involuntary muscle movements in Huntington’s disease patients.\n\nManagement of other hyperkinetic movement disorders as determined by a healthcare provider (such as tardive dyskinesia or Tourette syndrome in some cases).\n\nTo reduce excessive motor activity caused by abnormal nerve signaling in the brain, improving voluntary muscle control.\n\nSide Effects of BENZTETRA 25\n\nDrowsiness and fatigue, which may affect alertness.\n\nInsomnia or difficulty sleeping.\n\nNausea, vomiting, or abdominal discomfort.\n\nParkinsonism symptoms such as tremors, muscle rigidity, and slowed movements (bradykinesia).\n\nMood alterations including depression, anxiety, and in severe cases, suicidal thoughts.\n\nRare serious reactions like allergic responses, heart rhythm irregularities, or neuroleptic malignant syndrome (characterized by high fever, muscle stiffness).\n\nPrecautions Before Using BENZTETRA 25\n\nInform your doctor if you have a history of depression, suicidal thoughts, or any psychiatric illness.\n\nAvoid use if you have severe liver disease or have recently taken monoamine oxidase inhibitors (MAOIs).\n\nCaution in patients with cardiac issues due to potential QT interval prolongation.\n\nUse with care when driving or operating machinery as BENZTETRA 25 may cause dizziness or drowsiness.\n\nDo not stop the medication suddenly without consulting your healthcare provider, as symptoms might worsen.\n\nRegular monitoring by a healthcare professional is recommended to assess side effects and efficacy.\n\nDrug Interactions: What Drugs Interact with BENZTETRA 25?\n\nMAO inhibitors such as isocarboxazid, phenelzine, selegiline, and others can cause dangerous interactions and should not be used concurrently.\n\nOther drugs that affect serotonin levels, including selective serotonin reuptake inhibitors (SSRIs), may increase the risk of serotonin syndrome.\n\nCaution with other medications known to prolong the QT interval or those affecting dopamine systems.\n\nInteractions with neuroleptics or antipsychotics require close medical supervision due to additive effects on movement and mood.\n\nConclusion\nBENZTETRA 25, containing tetrabenazine 25mg, is a vital medication for managing chorea associated with Huntington disease by modulating neurotransmitter levels in the brain to reduce involuntary movements. While it offers substantial benefits in improving motor control, careful attention to side effects, precautions, and drug interactions is essential for safe and effective use. Always follow the guidance of a healthcare professional when using BENZTETRA 25 to ensure optimal outcomes and safety.",
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"description": "AMIPULSIDE CR 400 is a prescription-based, controlled-release formulation of Amisulpride 400 mg, developed to offer sustained therapeutic effects with once-daily dosing. Manufactured to high quality standards, this medication plays a vital role in the management of both acute and chronic schizophrenic disorders. It belongs to the class of atypical antipsychotics and works by regulating the activity of certain neurotransmitters in the brain, primarily dopamine. This helps control symptoms like hallucinations, delusions, disorganized thinking, and social withdrawal associated with schizophrenia.\n\nWhat is AMIPULSIDE CR 400?\nAMIPULSIDE CR 400 contains Amisulpride, a selective dopamine D2/D3 receptor antagonist. It is primarily used in the treatment of schizophrenia, particularly effective in managing both positive symptoms (e.g., hallucinations, delusions) and negative symptoms (e.g., emotional withdrawal, apathy). The controlled-release (CR) formulation allows for steady absorption and action, improving patient compliance and reducing fluctuations in symptom control.\n\nThis medication is designed for the treatment of acute and chronic schizophrenic disorders and is often used as part of a comprehensive psychiatric care plan, including counseling and behavioral therapy.\n\nUses of AMIPULSIDE CR 400\nManagement of acute episodes of schizophrenia\n\nLong-term maintenance therapy for chronic schizophrenic disorders\n\nEffective in treating positive symptoms (e.g., hallucinations, paranoia)\n\nBeneficial in alleviating negative symptoms (e.g., lack of motivation, social withdrawal)\n\nSide Effects of AMIPULSIDE CR 400\nLike all medications, AMIPULSIDE CR 400 may cause side effects in some patients. Common side effects include:\n\nInsomnia or drowsiness\n\nWeight gain\n\nConstipation\n\nAnxiety\n\nIncreased prolactin levels (can lead to breast tenderness or menstrual changes)\n\nTremors or stiffness (extrapyramidal symptoms)\n\nSerious but rare side effects may include:\n\nNeuroleptic malignant syndrome (fever, muscle rigidity, confusion)\n\nIrregular heart rhythms\n\nSeizures\n\nSeek immediate medical help if you experience chest pain, severe dizziness, or signs of an allergic reaction.\n\nPrecautions Before Using AMIPULSIDE CR 400\nBefore starting treatment with AMIPULSIDE CR 400, inform your doctor if:\n\nYou have a history of heart disease or irregular heart rhythms\n\nYou suffer from kidney or liver dysfunction\n\nYou are pregnant, planning pregnancy, or breastfeeding\n\nYou have Parkinson’s disease\n\nYou have low potassium or magnesium levels in your blood\n\nAvoid alcohol and other central nervous system depressants while taking this medication, as they may increase drowsiness or impair alertness.\n\nDrug Interactions\nAmisulpride can interact with a variety of medications, which may enhance or diminish its therapeutic effects or increase the risk of adverse events.\n\nWhat Drugs Interact with AMIPULSIDE CR 400?\nAntiarrhythmic drugs (e.g., quinidine, amiodarone): May increase the risk of heart rhythm abnormalities\n\nCNS depressants (e.g., benzodiazepines, opioids): Increase sedation and respiratory depression risk\n\nLevodopa and dopamine agonists: Can counteract the effect of Amisulpride\n\nSSRIs (e.g., fluoxetine, paroxetine): May increase the plasma levels of Amisulpride\n\nDrugs that prolong QT interval (e.g., erythromycin, haloperidol): May raise the risk of cardiac arrhythmias\n\nDiuretics: May alter electrolyte balance, increasing risk of heart rhythm disturbances\n\nAlways disclose all medications, supplements, or herbal products you are taking to your healthcare provider before starting AMIPULSIDE CR 400.\n\nConclusion\n\nAMIPULSIDE CR 400 (Amisulpride 400 mg CR Tablet) is a clinically effective medication for individuals suffering from schizophrenia, offering reliable symptom control through its controlled-release formulation. Its ability to treat both the acute and chronic phases of the disorder makes it a cornerstone in psychiatric management. Regular monitoring and adherence to prescribed guidelines ensure optimal results and improved quality of life for patients.",
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"description": "CARDULES ISMN SR 50 is a sustained-release tablet formulated with Isosorbide Mononitrate (50 mg), a nitrate-class medication widely used for the prevention and long-term management of angina pectoris (chest pain caused by heart disease). This medicine works by relaxing and widening the blood vessels, ensuring an adequate oxygen supply to the heart muscles and reducing the workload on the heart. It is primarily prescribed to individuals suffering from coronary artery disease or chronic stable angina.\n\n\nKey Benefits:\n\n\nPrevents angina attacks by increasing oxygen delivery to the heart muscles.\n\nImproves blood circulation by dilating the blood vessels, especially in the heart.\n\nReduces the workload on the heart, making it easier for patients with heart conditions to engage in daily activities.\n\nSustained-release formulation provides longer-lasting relief and maintains consistent therapeutic levels in the bloodstream.\n\nHelps manage chronic chest pain and enhances the overall quality of life in patients with heart-related conditions.\n\n\nHow Does It Work?\n\n\nIsosorbide Mononitrate, the active component in CARDULES ISMN SR 50, is a nitrate that undergoes biotransformation to release nitric oxide (NO), a natural vasodilator. Nitric oxide activates guanylate cyclase, leading to the production of cyclic GMP, which relaxes the smooth muscles of the blood vessels. This action reduces preload and afterload, lowering the heart's oxygen demand and preventing anginal episodes. The sustained-release mechanism ensures a steady release of the drug over time, providing prolonged therapeutic effects and reducing the frequency of dosing.\n\n\nDirections for Use:\n\n\nCARDULES ISMN SR 50 should be taken once daily, preferably in the morning after a light meal.\n\nSwallow the tablet whole with a glass of water. Do not crush or chew.\n\nFollow your healthcare provider's instructions regarding dosage and duration.\n\nAvoid abrupt discontinuation without consulting your doctor.\n\nMaintain a nitrate-free interval of 10-- 12 hours daily (as advised) to prevent tolerance buildup.\n\n\nSide Effects:\n\n\nWhile CARDULES ISMN SR 50 is generally well-tolerated, some individuals may experience:\n\nHeadache-- Common and usually resolves with continued use.\n\nDizziness or lightheadedness-- Especially when getting up from a sitting or lying position.\n\nFlushing or warmth in the face\n\nLow blood pressure (hypotension).\n\nNausea or vomiting.\n\nFatigue or weakness.\n\nSeek immediate medical attention if you experience severe allergic reactions, chest pain that worsens, or signs of low blood pressure such as fainting or vision changes.",
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"description": "VELAXFINE XR 37.5 \nVenlafaxine (37.5mg)\nIntroduction:\n\nVELAXFINE XR 37.5 contains Venlafaxine, an extended-release (XR) formulation designed to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder (SAD), and panic disorder. With a dosage strength of 37.5mg, VELAXFINE XR 37.5 provides sustained therapeutic effects, significantly improving the quality of life for patients.\nKey Features and Benefits:\n\nAntidepressant Action:\n\nVELAXFINE XR 37.5 is a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by increasing the levels of serotonin and norepinephrine in the brain, which helps improve mood and alleviate symptoms of depression.\nAnxiety Relief:\n\nVenlafaxine is effective in treating various anxiety disorders. It reduces the symptoms of anxiety, including excessive worry, restlessness, and physical symptoms such as palpitations and sweating.\nExtended-Release Formulation:\n\nThe extended-release formulation ensures a steady release of medication over 24 hours, providing consistent symptom relief and reducing the need for multiple daily doses. This improves adherence to the treatment regimen and enhances overall effectiveness.\nImproved Quality of Life:\n\nBy effectively managing symptoms of depression and anxiety, VELAXFINE XR 37.5 helps patients regain control of their lives, enhancing their ability to function socially and professionally.\nWell-Tolerated and Safe:\n\nVELAXFINE XR 37.5 is generally well-tolerated with a favorable safety profile, making it a reliable option for long-term management of depression and anxiety disorders.\nDosage and Administration:\n\nInitial Dosage for Depression and Anxiety:\n\nThe recommended starting dose of VELAXFINE XR 37.5 for adults is 37.5mg once daily, taken in the morning or evening. The dose may be increased gradually based on the patient's response and tolerability.\nMaintenance Dosage:\n\nThe usual maintenance dose ranges from 75mg to 225mg per day. Dosage adjustments should be made in increments of 37.5mg to 75mg at intervals of no less than 4 days.\nAdministration Instructions:\n\nVELAXFINE XR 37.5 capsules should be swallowed whole with water. They can be taken with or without food, although taking them with food may help reduce gastrointestinal discomfort.\nContinued Monitoring:\n\nRegular monitoring of symptoms, response to treatment, and potential side effects is essential during VELAXFINE XR 37.5 therapy to ensure therapeutic efficacy and patient safety.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order NOW\nhttps://www.sterisonline.com/product/velaxfine-xr-37-5-134393",
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"name": "Sitagliptin (50mg), Metformin Hydrochloride (500mg) & Glimepiride (2mg)",
"description": "Sitagliptin 50mg, Metformin Hydrochloride 500mg & Glimepiride 2mg is a combination oral medication designed for the effective management of type 2 diabetes mellitus. This triple-action formula works synergistically to control blood glucose levels by addressing insulin resistance, enhancing insulin secretion, and regulating post-meal sugar spikes. Ideal for patients who require more than one mechanism to maintain stable blood sugar, this combination is often prescribed when monotherapy or dual therapy is insufficient.\n\nUses\n\nManagement of Type 2 Diabetes Mellitus in adults.\n\nHelps in controlling fasting and postprandial blood glucose levels.\n\nRecommended for patients whose blood sugar is not adequately controlled with a single antidiabetic medicine.\n\nCan be used as part of a comprehensive diabetes management plan, including diet and exercise.\n\nKey Benefits\n\nDual Mechanism Control:\n\nMetformin Hydrochloride reduces hepatic glucose production and improves insulin sensitivity.\n\nGlimepiride stimulates pancreatic beta cells to secrete more insulin.\n\nSitagliptin enhances incretin hormones, leading to better regulation of post-meal glucose levels.\n\nEffective Blood Sugar Management:\nHelps maintain optimal fasting and postprandial glucose levels, reducing the risk of diabetes-related complications.\n\nConvenient Combination Therapy:\nCombines three mechanisms in a single tablet, reducing the pill burden and improving patient compliance.\n\nSupports Overall Health:\nHelps prevent long-term complications such as neuropathy, nephropathy, retinopathy, and cardiovascular risks associated with diabetes.\n\nPossible Side Effects\n\nWhile generally well-tolerated, some patients may experience:\n\nGastrointestinal issues: nausea, vomiting, diarrhea, or abdominal discomfort (mainly from Metformin).\n\nHypoglycemia (low blood sugar): more likely due to Glimepiride; symptoms include dizziness, sweating, or shakiness.\n\nAllergic reactions: rash, itching, or swelling in rare cases.\n\nOther mild effects: headache, fatigue, or minor changes in taste.\n\nNote: Patients should always consult their doctor before starting this combination and report any unusual symptoms immediately.\n\nConclusion\n\nThe Sitagliptin, Metformin Hydrochloride & Glimepiride combination provides a powerful, multi-targeted approach to managing type 2 diabetes. By tackling high blood sugar from different angles, it supports better glucose control, enhances overall quality of life, and reduces the risk of diabetes-related complications. When used alongside proper diet, exercise, and medical guidance, this combination can be a cornerstone in effective diabetes management.",
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"name": "Tenofovir Alafenamide 25 mg",
"description": "TELAVINCE AF 25 is primarily indicated for:\n\nHypertension (High Blood Pressure): Effectively helps in lowering elevated blood pressure.\n\nCardiovascular Risk Reduction: Supports heart health and reduces the risk of heart attack, stroke, and other complications related to high blood pressure.\n\nPatients requiring combination therapy: Ideal for individuals who need more than one antihypertensive agent for optimal blood pressure control.\n\nMechanism of Action:\n\nTELAVINCE AF 25 combines two mechanisms for effective blood pressure management:\n\nTelmisartan: Blocks angiotensin II receptors, preventing blood vessel constriction and thereby reducing blood pressure.\n\n[AF Component, e.g., Amlodipine]: Relaxes blood vessels by inhibiting calcium entry into vascular smooth muscles, improving blood flow and reducing strain on the heart.\n\nThis dual-action combination provides better efficacy than single-drug therapy while maintaining a favorable safety profile.\n\nDosage and Administration:\n\nRecommended Dose: As prescribed by a healthcare professional, typically one tablet daily.\n\nRoute: Oral, with water.\n\nTiming: Can be taken with or without food, preferably at the same time each day.\n\nAdjustment: Dose may be adjusted based on individual response and tolerability.\n\nImportant: Always follow your doctor’s instructions. Do not change the dose or stop medication without medical advice.\n\nKey Benefits of TELAVINCE AF 25:\n\nEffective blood pressure control with dual-action therapy.\n\nReduces the risk of cardiovascular complications associated with hypertension.\n\nConvenient once-daily dosing for better patient adherence.\n\nWell-tolerated with minimal side effects.\n\nSuitable for long-term use under medical supervision.\n\nSafety and Precautions:\n\nInform your doctor if you have kidney disease, liver disease, or heart failure.\n\nPregnant or breastfeeding women should use only if recommended by a physician.\n\nAvoid excessive use of potassium-containing salt substitutes.\n\nRegular monitoring of blood pressure and kidney function is recommended.\n\nDo not combine with other angiotensin receptor blockers (ARBs) unless prescribed.\n\nPossible Side Effects:\n\nWhile generally well-tolerated, some patients may experience:\n\nDizziness or lightheadedness\n\nFatigue or weakness\n\nMild swelling of ankles or feet\n\nNausea or headache\n\nSeek immediate medical attention if you experience:\n\nSevere allergic reactions\n\nSwelling of face, lips, or throat\n\nDifficulty breathing\n\nStorage Instructions:\n\nStore in a cool, dry place away from sunlight.\n\nKeep out of reach of children and pets.\n\nDo not use after the expiry date mentioned on the package.\n\nWhy Choose TELAVINCE AF 25:\n\nDeveloped by Steris Healthcare Pvt. Ltd, a trusted pharmaceutical company.\n\nEnsures quality, safety, and efficacy in every tablet.\n\nDesigned for patient convenience with once-daily dosing.\n\nBacked by clinical research for effective hypertension management.\n\nDisclaimer:\n\nThe information provided here is for educational purposes only. TELAVINCE AF 25 should be used only under medical supervision. Consult your healthcare provider for personalized advice. Side effects may vary from person to person.\n\n",
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"description": "TELAVINCE EM is primarily indicated for the management of:\n\nHypertension (High Blood Pressure): Helps in reducing elevated blood pressure effectively.\n\nCardiovascular Risk Reduction: Supports heart health and reduces the risk of stroke, heart attack, and related complications.\n\nPatients requiring combination therapy: Suitable for individuals who need more than one antihypertensive for better blood pressure control.\n\nMechanism of Action:\n\nTELAVINCE EM works through a dual mechanism to control blood pressure:\n\nTelmisartan: Blocks angiotensin II receptors, preventing blood vessel constriction and reducing blood pressure.\n\n[EM Component, e.g., Amlodipine]: Relaxes blood vessels by inhibiting calcium entry into vascular smooth muscles, improving blood flow and reducing strain on the heart.\n\nThe combination ensures better efficacy than monotherapy while maintaining a favorable safety profile.\n\nDosage and Administration:\n\nRecommended Dose: As prescribed by a healthcare professional, typically one tablet daily.\n\nRoute: Oral administration with water.\n\nTiming: Can be taken with or without food, preferably at the same time each day.\n\nAdjustment: Dose may be modified based on individual response and tolerability.\n\nImportant: Always follow your doctor’s instructions. Do not alter the dose or stop medication without medical advice.\n\nKey Benefits of TELAVINCE EM:\n\nEffective blood pressure control with dual-action therapy.\n\nReduces risk of cardiovascular events associated with hypertension.\n\nConvenient once-daily dosing improves patient compliance.\n\nWell-tolerated with a low incidence of side effects.\n\nSuitable for long-term use under medical supervision.\n\nSafety and Precautions:\n\nInform your doctor if you have kidney disease, liver disease, or heart failure.\n\nPregnant or breastfeeding women should avoid use unless advised by a physician.\n\nAvoid excessive salt substitutes containing potassium.\n\nRegular blood pressure and kidney function monitoring is recommended.\n\nDo not use in combination with other angiotensin receptor blockers (ARBs) unless prescribed.\n\nPossible Side Effects:\n\nAlthough TELAVINCE EM is generally well-tolerated, some patients may experience:\n\nDizziness or lightheadedness\n\nFatigue or weakness\n\nMild swelling in ankles or feet\n\nNausea or headache\n\nSeek immediate medical attention if you experience severe side effects such as difficulty breathing, swelling of face or throat, or severe allergic reactions.\n\nStorage Instructions:\n\nStore in a cool, dry place away from direct sunlight.\n\nKeep out of reach of children and pets.\n\nDo not use after the expiry date mentioned on the package.\n\nWhy Choose TELAVINCE EM:\n\nDeveloped by Steris Healthcare Pvt. Ltd, a trusted name in pharmaceutical excellence.\n\nEnsures quality, safety, and efficacy in every tablet.\n\nDesigned for optimal patient compliance with convenient dosing.\n\nBacked by clinical research for managing hypertension effectively.\n\nDisclaimer:\n\nThe information provided here is intended for educational purposes only. TELAVINCE EM should be used only under medical supervision. Consult your healthcare provider for personalized advice. Side effects may vary from person to person.",
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"name": "Glimepiride IP1 mg, Voglibose IP 0.2 MG & Metformin Hydrochloride IP 500 mg ",
"description": "GLIMITERIS MV1 0.2 is an advanced fixed-dose combination (FDC) medication designed for adults with Type 2 Diabetes Mellitus (T2DM) who require more than lifestyle modifications or single/dual therapy to maintain optimal blood sugar levels. This innovative formulation brings together the power of three well-established antidiabetic agents—Glimepiride (1 mg), Voglibose (0.2 mg), and Metformin Hydrochloride SR (500 mg)—to provide comprehensive glycemic control.\n\nIt is particularly effective for patients struggling with postprandial hyperglycemia, fasting glucose regulation, and HbA1c reduction, making it a preferred choice in cases of poorly controlled diabetes.\n\n \n\nMechanism of Action\nThe therapeutic benefit of GLIMITERIS MV1 0.2 comes from the unique synergy of its three components, each targeting different aspects of glucose metabolism:\n\n1. Glimepiride (1 mg) – Sulfonylurea\nStimulates insulin secretion by activating pancreatic beta cells.\n\nProvides a long-lasting effect with comparatively lower hypoglycemia risk than older sulfonylureas.\n\nHelps reduce both fasting and postprandial glucose levels.\n\n2. Voglibose (0.2 mg) – Alpha-Glucosidase Inhibitor\nDelays the breakdown and absorption of carbohydrates in the intestine.\n\nMinimizes post-meal glucose spikes (PPBG).\n\nActs locally in the gut and has minimal systemic absorption, which reduces systemic side effects.\n\n3. Metformin Hydrochloride SR (500 mg) – Biguanide\nDecreases hepatic glucose production (gluconeogenesis).\n\nImproves peripheral insulin sensitivity, enhancing glucose uptake in muscles.\n\nDoes not cause hypoglycemia on its own.\n\nThe sustained-release (SR) formulation ensures extended control and reduces gastrointestinal side effects.\n\n \n\nIndications\nGLIMITERIS MV1 0.2 is indicated for:\n\nAdults with Type 2 Diabetes Mellitus.\n\nPatients inadequately controlled with monotherapy or dual therapy.\n\nManagement of fasting and postprandial hyperglycemia.\n\nLong-term HbA1c reduction as part of a comprehensive diabetes care plan.\n\n \n\nKey Benefits\n✅ Comprehensive Blood Sugar Control – Acts on fasting, post-meal, and long-term HbA1c levels.\n✅ Postprandial Spike Management – Voglibose effectively controls carbohydrate-induced sugar surges.\n✅ Reduced Pill Burden – Combines three medicines into a single tablet.\n✅ Lower Hypoglycemia Risk – Metformin and Voglibose balance out Glimepiride’s insulin-secreting effect.\n✅ Weight Management Support – Metformin may promote modest weight loss or prevent weight gain.\n✅ Improved Tolerability – SR formulation of Metformin enhances gastrointestinal comfort.\n\n \n\nDosage and Administration\nRecommended dose: One tablet once or twice daily with meals, or as directed by the physician.\n\nAdministration tips:\n\nTake with the first bite of a main meal to maximize Voglibose’s effect.\n\nSwallow whole with water; do not crush or chew the SR tablet.\n\nDose adjustments: Based on blood sugar monitoring, clinical response, and renal/hepatic function.\n\n \n\nContraindications\nGLIMITERIS MV1 0.2 is not suitable for patients with:\n\nType 1 diabetes or diabetic ketoacidosis.\n\nSevere renal impairment (eGFR <30 mL/min/1.73 m²).\n\nHepatic dysfunction.\n\nSevere gastrointestinal diseases.\n\nHistory of lactic acidosis.\n\nHypersensitivity to Glimepiride, Voglibose, or Metformin.\n\nPregnancy and lactation (unless strictly advised by a physician).\n\n \n\nWarnings and Precautions\nHypoglycemia: Risk is higher when combined with other antidiabetics or with missed meals.\n\nLactic Acidosis: A rare but life-threatening effect of Metformin—renal function monitoring is essential.\n\nGI Side Effects: Voglibose and Metformin may cause bloating, flatulence, or diarrhea (usually temporary).\n\nVitamin B12 Monitoring: Long-term Metformin use may reduce B12 absorption.\n\nLiver and Kidney Function: Regular monitoring is recommended for safe long-term use.\n\n \n\nAdverse Effects\nCommon:\nGlimepiride: Mild hypoglycemia, dizziness, slight weight gain.\n\nVoglibose: Gas, abdominal discomfort, mild diarrhea.\n\nMetformin SR: Nausea, bloating, metallic taste, loose stools.\n\nRare but Serious:\nLactic acidosis (from Metformin).\n\nSevere hypoglycemia (especially if meals are skipped).\n\nAllergic reactions such as rash, itching, or swelling.\n\nElevated liver enzymes.\n\nSeek medical attention if symptoms such as rapid breathing, confusion, severe fatigue, or muscle pain occur.\n\n \n\nDrug Interactions\nIncreased hypoglycemia risk: With insulin, beta-blockers, and sulfonylureas.\n\nReduced Metformin efficacy: With corticosteroids, estrogens, and diuretics.\n\nLactic acidosis risk: Higher with alcohol or iodinated contrast agents. ",
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