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{ "products": [ { "_id": "694cf85408591c1173b54c2f", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Pregabalin Epalrestat and Methylcobalamin Tablets", "description": "EPSTATE ED represents an advanced pharmaceutical formulation that combines three powerful therapeutic agents: Pregabalin, Epalrestat, and Methylcobalamin. This innovative triple-combination medication is specifically designed to address the complex pathophysiology of diabetic neuropathy and neuropathic pain conditions. By integrating multiple mechanisms of action, EPSTATE ED offers a comprehensive approach to managing nerve-related complications that significantly impact the quality of life for millions of individuals worldwide.\nThe formulation addresses not only the symptomatic relief of neuropathic pain but also targets the underlying metabolic derangements that contribute to nerve damage progression. This multi-pronged therapeutic strategy makes EPSTATE ED particularly valuable for patients who require more than symptomatic management alone.\nUnderstanding the Active Components\nPregabalin: The Neuropathic Pain Modulator\nPregabalin serves as the cornerstone analgesic component in EPSTATE ED. This anticonvulsant medication works by binding to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. Through this mechanism, Pregabalin reduces the release of excitatory neurotransmitters including glutamate, norepinephrine, and substance P. This reduction in neurotransmitter release effectively dampens the abnormal neural signaling that characterizes neuropathic pain conditions.\nThe molecule demonstrates excellent bioavailability and rapid absorption, allowing patients to experience relief within a relatively short timeframe. Its efficacy in managing various neuropathic pain syndromes has been extensively documented in clinical trials, establishing it as a first-line agent for diabetic peripheral neuropathy, postherpetic neuralgia, and other chronic neuropathic pain conditions.\nEpalrestat: The Aldose Reductase Inhibitor\nEpalrestat represents a unique addition to the formulation, functioning as a selective aldose reductase inhibitor. In diabetic conditions, excess glucose is converted to sorbitol through the polyol pathway, with aldose reductase serving as the rate-limiting enzyme. The accumulation of sorbitol within nerve cells leads to osmotic stress, depletion of myoinositol, and subsequent nerve dysfunction.\nBy inhibiting aldose reductase, Epalrestat prevents this harmful sorbitol accumulation, thereby addressing one of the fundamental metabolic abnormalities responsible for diabetic neuropathy. This disease-modifying approach distinguishes EPSTATE ED from purely symptomatic treatments. Epalrestat has been particularly well-studied in Asian populations and has demonstrated the ability to improve nerve conduction velocities and reduce subjective neuropathic symptoms over time.\nMethylcobalamin: The Neurotropic Vitamin\nMethylcobalamin, the bioactive form of Vitamin B12, completes the therapeutic triad in EPSTATE ED. Unlike cyanocobalamin, which requires conversion in the body, methylcobalamin is immediately available for utilization in crucial biochemical processes. It plays an indispensable role in myelin synthesis, the protective sheath surrounding nerve fibers that enables proper signal transmission.\nThis coenzyme participates in methionine synthesis and is essential for maintaining the structural and functional integrity of neurons. Methylcobalamin also facilitates nerve regeneration and has demonstrated neuroprotective properties in various experimental models. For patients with diabetic neuropathy, who often exhibit Vitamin B12 deficiency (sometimes exacerbated by metformin therapy), supplementation with methylcobalamin addresses both nutritional deficits and supports nerve health at a fundamental level.\nClinical Applications and Uses\nEPSTATE ED is primarily indicated for the comprehensive management of diabetic peripheral neuropathy, a condition affecting approximately 50% of individuals with long-standing diabetes. The symptoms of this condition range from tingling sensations and burning pain to numbness and loss of protective sensation, which can lead to serious complications including foot ulcers and amputations.\nBeyond diabetic neuropathy, EPSTATE ED may be prescribed for various neuropathic pain syndromes where the combination of pain relief, metabolic correction, and nerve support proves beneficial. Patients experiencing chronic nerve pain resulting from metabolic disturbances, nutritional deficiencies, or structural nerve damage may find this combination particularly effective.\nThe medication is typically recommended for adults who have not achieved adequate symptom control with single-agent therapy or who would benefit from the synergistic effects of the three components. Healthcare providers may prescribe EPSTATE ED when a patient requires both immediate symptom relief and long-term disease modification.\nKey Benefits and Therapeutic Advantages\nComprehensive Multi-Mechanism Action\nThe primary advantage of EPSTATE ED lies in its multi-faceted approach to neuropathic conditions. Rather than addressing only pain symptoms, the formulation simultaneously tackles pain perception, underlying metabolic abnormalities, and nutritional support for nerve health. This comprehensive strategy may lead to superior outcomes compared to monotherapy approaches.\nEnhanced Pain Relief\nClinical evidence supporting Pregabalin's efficacy in neuropathic pain is substantial. Patients often report significant reductions in pain intensity, improved sleep quality due to decreased nocturnal pain, and enhanced ability to perform daily activities. The pain-relieving effects typically manifest within the first week of therapy and continue to improve with ongoing treatment.\nDisease Modification Potential\nUnlike purely symptomatic treatments, the inclusion of Epalrestat provides genuine disease-modifying potential. By targeting the polyol pathway, EPSTATE ED may slow the progression of nerve damage in diabetic patients. Long-term use may preserve nerve function and prevent the worsening of neuropathic symptoms, offering hope beyond mere symptom management.\nImproved Nerve Conduction and Function\nThe combination of metabolic correction through Epalrestat and neurotropic support via Methylcobalamin creates an environment conducive to nerve regeneration and functional improvement. Studies have demonstrated improvements in nerve conduction velocity parameters with similar combination therapies, suggesting potential restoration of nerve function rather than simple symptom masking.\nConvenience of Combination Therapy\nFor patients who would otherwise require multiple separate medications, EPSTATE ED offers the convenience of a single tablet containing all three therapeutic agents. This simplification of medication regimens improves compliance, reduces pill burden, and may enhance overall treatment outcomes.\nQuality of Life Enhancement\nThe cumulative effect of pain reduction, improved nerve function, and better metabolic control translates into meaningful quality of life improvements. Patients report better mobility, reduced interference of pain with daily activities, improved mood, and enhanced social functioning.\nPotential Side Effects and Safety Considerations\nCommon Side Effects\nAs with any pharmaceutical agent, EPSTATE ED may produce certain adverse effects. The most commonly reported side effects are primarily attributable to the Pregabalin component and include dizziness, somnolence, peripheral edema, dry mouth, blurred vision, weight gain, and difficulty with concentration or attention. These effects are generally mild to moderate and often diminish with continued therapy as the body adapts to the medication.\nGastrointestinal symptoms such as constipation or nausea may occur, though they are typically manageable with dietary modifications or symptomatic treatment. Some patients experience increased appetite leading to weight gain, which requires monitoring, particularly in diabetic individuals where weight management is crucial.\nSerious but Rare Adverse Events\nThough uncommon, certain serious adverse effects warrant immediate medical attention. These include allergic reactions manifesting as rash, itching, swelling, severe dizziness, or breathing difficulties. Pregabalin has been associated with rare cases of angioedema, which requires prompt discontinuation and medical intervention.\nMental health changes, including mood alterations, anxiety, depression, agitation, or suicidal thoughts, have been reported with Pregabalin use, particularly in individuals with pre-existing psychiatric conditions. Patients and caregivers should remain vigilant for behavioral changes and report them immediately to healthcare providers.\nDrug Interactions and Precautions\nEPSTATE ED may interact with other central nervous system depressants, including alcohol, opioids, benzodiazepines, and antihistamines, potentially intensifying sedation and cognitive impairment. Patients should inform their healthcare provider of all medications, supplements, and substances they consume.\nIndividuals with kidney impairment require dose adjustments since Pregabalin is primarily eliminated through renal excretion. Regular monitoring of renal function may be necessary during long-term therapy.\nSpecial Population Considerations\nPregnant or breastfeeding women should use EPSTATE ED only when clearly necessary and under strict medical supervision, as the safety profile in these populations has not been fully established. Elderly patients may be more susceptible to side effects, particularly dizziness and confusion, necessitating careful dose titration and monitoring.\nPatients should be advised against abrupt discontinuation of EPSTATE ED, as sudden cessation of Pregabalin may precipitate withdrawal symptoms including insomnia, nausea, headache, anxiety, and sweating. Gradual dose reduction under medical supervision is recommended when discontinuing therapy.\nDosage and Administration Guidelines\nThe appropriate dosage of EPSTATE ED is highly individualized and should be determined by a qualified healthcare professional based on the patient's specific condition, response to therapy, and tolerance. Typically, treatment begins with a lower dose that is gradually increased to achieve optimal therapeutic benefit while minimizing adverse effects.\nPatients should take EPSTATE ED exactly as prescribed, with or without food, at consistent times each day to maintain stable blood levels. Missing doses should be addressed by taking the forgotten dose as soon as remembered, unless it's nearly time for the next scheduled dose. Double dosing to compensate for missed doses is not recommended.\nRegular follow-up appointments allow healthcare providers to assess treatment efficacy, monitor for adverse effects, and make necessary dose adjustments. Patients should maintain open communication with their medical team regarding symptom improvement, side effects, and any concerns that arise during therapy.\nPatient Counseling and Lifestyle Recommendations\nMaximizing the benefits of EPSTATE ED extends beyond simply taking the medication. Patients should be counseled on complementary lifestyle measures that support neuropathy management. Maintaining optimal glycemic control remains paramount for diabetic patients, as blood sugar management directly impacts neuropathy progression regardless of medication.\nRegular physical activity, within individual capabilities, promotes circulation, supports nerve health, and may enhance the therapeutic effects of EPSTATE ED. Daily foot examinations become critical for diabetic patients to identify potential injuries early, preventing serious complications.\nNutritional optimization, including adequate intake of B vitamins, antioxidants, and essential nutrients, supports the neurotropic effects of Methylcobalamin. Avoiding alcohol and tobacco, both of which can exacerbate neuropathy, is strongly recommended.\nPatients should be cautioned about activities requiring alertness, such as driving or operating machinery, especially during the initial treatment phase when dizziness and somnolence may be more pronounced. These effects typically improve with continued therapy, but individual responses vary.\nConclusion\nEPSTATE ED represents a thoughtfully designed pharmaceutical formulation that addresses the multifaceted nature of diabetic neuropathy and neuropathic pain through its unique combination of Pregabalin, Epalrestat, and Methylcobalamin. This triple-action approach offers patients more than symptomatic relief—it provides genuine disease modification potential, nutritional support, and comprehensive nerve health optimization.\nThe synergistic effects of these three components create a therapeutic profile that is greater than the sum of its parts. While Pregabalin efficiently manages pain symptoms and improves quality of life in the short term, Epalrestat works to address underlying metabolic derangements that drive disease progression, and Methylcobalamin provides essential neurotropic support for nerve regeneration and function.\nFor patients struggling with the debilitating effects of neuropathic pain and diabetic neuropathy, EPSTATE ED offers renewed hope for better symptom control and potentially slowed disease progression. The convenience of combination therapy in a single tablet improves adherence and simplifies complex treatment regimens.\nHowever, EPSTATE ED is not without considerations. Potential side effects, though generally manageable, require awareness and monitoring. The medication is most effective when integrated into a comprehensive management plan that includes optimal glycemic control, lifestyle modifications, and regular medical supervision.\nUltimately, EPSTATE ED should be viewed as a valuable tool in the therapeutic arsenal against neuropathic conditions, best utilized under the guidance of knowledgeable healthcare professionals who can individualize treatment to each patient's unique needs and circumstances. With proper use, monitoring, and patient education, EPSTATE ED can significantly improve outcomes and quality of life for those affected by these challenging neurological conditions.", "price": 275.0, "discountamount": 82.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2253, "imageuri": "https://productimages.withfloats.com/actual/694cf859d25fa0b0657b1ac8.png", "tileimageuri": "https://productimages.withfloats.com/tile/694cf859d25fa0b0657b1ac8.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-25T08:39:48.947Z", "updatedon": "2026-04-18T09:21:49.885Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/pregabalin-epalrestat-and-methylcobalamin-tablets/2253", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "EPSTATE ED", "category": "NEUROLOGYRANGE", "tags": [ "regabalin, Epalrestat, and Methylcobalamin.neuropathic pain conditions.", "Pregabalin, Epalrestat, and Methylcobalamin.", "neuropathic pain.", "diabetic neuropathy.", "sorbitol within nerve cells leads to osmotic stress.", "Epalrestat and neurotropic support via Methylcobalamin creates an environment .", "mood alterations, anxiety, depression, agitation.", "supports the neurotropic effects of Methylcobalamin.", "Pregabalin Epalrestat and Methylcobalamin Tablets", "epalrestat and methylcobalamin tablets uses", "epalrestat and methylcobalamin tablets in hindi", "pregabalin epalrestat and methylcobalamin tablets price jaipur", "pregabalin epalrestat and methylcobalamin tablets price india" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6917218c6e3de7f45cff9997", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Gabapentin and Lidocaine Hydrochloride Gel ", "description": "Gabapentin and Lidocaine Hydrochloride is a specialized combination therapy primarily used to manage neuropathic pain—pain resulting from nerve damage, irritation, or dysfunction. This blend unites two highly effective agents: gabapentin, an anticonvulsant widely used for nerve-related pain, and lidocaine hydrochloride, a fast-acting local anesthetic that numbs nerve signals in targeted areas. Together, they deliver both systemic and localized pain relief, making the product ideal for patients seeking comprehensive control of chronic or acute neuropathic symptoms.\n\nThis combination may appear in different formulations, such as topical creams, patches, or oral gabapentin used alongside lidocaine topical therapy. The synergistic action makes it especially beneficial for individuals who do not achieve adequate relief from a single medication. By addressing pain through two different mechanisms—central nerve modulation (gabapentin) and peripheral nerve numbing (lidocaine)—this combination delivers a balanced approach to pain management with reduced need for stronger systemic medications.\n\nGabapentin works by calming overactive nerve signals in the central nervous system. It binds to calcium channels in the brain and spinal cord, reducing the abnormal firing responsible for neuropathic discomfort. Lidocaine, on the other hand, blocks sodium channels in peripheral nerves, preventing pain signals from traveling to the brain. Together, they create a powerful relief profile suitable for various nerve-related conditions.\n\nUses of Gabapentin and Lidocaine Hydrochloride\n\nThis combination is commonly recommended for patients dealing with complex nerve pain. Typical uses include:\n\n1. Neuropathic Pain\n\nIdeal for conditions such as:\n\nPeripheral neuropathy\n\nDiabetic neuropathy\n\nChemotherapy-induced neuropathy\n\nPost-surgical nerve pain\n\n2. Postherpetic Neuralgia (PHN)\n\nPatients recovering from shingles often experience burning, sharp, or stabbing nerve pain. Lidocaine patches offer localized relief, while gabapentin reduces the intensity of nerve signaling.\n\n3. Sciatica and Radicular Pain\n\nWhen pain radiates from the spine to the legs or arms due to nerve compression, this combination offers both deep and surface-level relief.\n\n4. Fibromyalgia\n\nGabapentin may reduce widespread nerve sensitivity, while lidocaine provides targeted relief in high-pain areas.\n\n5. Localized Musculoskeletal or Joint Pain With Nerve Involvement\n\nLidocaine can temporarily numb sensitive regions, while gabapentin addresses chronic nerve irritation.\n\nKey Benefits\n1. Dual-Action Pain Relief\n\nGabapentin works internally to stabilize nerve activity, while lidocaine provides immediate external numbing. This dual approach addresses pain from both ends.\n\n2. Reduced Need for Strong Systemic Painkillers\n\nMany patients experience significant relief without relying on opioids or sedatives.\n\n3. Rapid Onset from Lidocaine\n\nTopical lidocaine begins relieving pain within minutes by blocking peripheral nerve transmission.\n\n4. Long-Term Nerve Modulation from Gabapentin\n\nGabapentin’s central action builds gradually, offering sustained reduction of chronic nerve pain with consistent use.\n\n5. Versatile Application\n\nThe combination can be tailored to individual needs—oral gabapentin for long-term control and lidocaine patches or gel for targeted, immediate comfort.\n\n6. Improved Daily Function\n\nBy reducing constant nerve irritation, patients often regain mobility, sleep quality, and overall comfort.\n\nPossible Side Effects\nGabapentin Side Effects\n\nCommon:\n\nDizziness\n\nDrowsiness\n\nFatigue\n\nMild swelling in the legs\n\nCoordination problems\n\nLess common but important:\n\nMood changes\n\nBlurred vision\n\nDifficulty concentrating\n\nLidocaine Hydrochloride Side Effects\n\nCommon:\n\nSkin redness or irritation\n\nTemporary numbness\n\nMild burning or itching at application site\n\nRare but serious:\n\nAllergic reactions\n\nIrregular heartbeat (with excessive use)\n\nSystemic toxicity if large amounts are absorbed\n\nPatients should follow dosing instructions carefully and avoid applying lidocaine to broken skin unless instructed.\n\nConclusion\n\nThe combination of Gabapentin and Lidocaine Hydrochloride represents a powerful and effective solution for individuals struggling with neuropathic pain. By blending the internal nerve-calming effects of gabapentin with the fast-acting local numbing properties of lidocaine, this therapy covers multiple pain pathways simultaneously. It offers significant relief for conditions such as diabetic neuropathy, shingles-related pain, nerve compression syndromes, and chronic nerve-related disorders.", "price": 250.0, "discountamount": 75.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2206, "imageuri": "https://productimages.withfloats.com/actual/6917218e632ad4b43b4993ca.png", "tileimageuri": "https://productimages.withfloats.com/tile/6917218e632ad4b43b4993ca.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-14T12:33:16.079Z", "updatedon": "2026-05-20T11:53:15.762Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//gabapentin-and-lidocaine-hydrochloride-gel-/2206", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "STARGAB LIDO", "category": "NEUROLOGYRANGE", "tags": [ "Gabapentin and Lidocaine Hydrochloride", "neuropathic pain", "nerve damage", "bladder dysfunctions.", "neuropathic symptoms" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "666c0208d89239081848a527", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "STARGAB 300 ", "description": "STARGAB 300 \nGabapentin 300 mg\nIntroduction:\n\nSTARGAB 300 contains Gabapentin, a versatile anticonvulsant and neuropathic pain agent widely used to manage conditions such as epilepsy and neuropathic pain. With a dosage strength of 300mg, STARGAB 300 aims to alleviate symptoms by modulating neurotransmitter release, thereby improving quality of life for patients.\nKey Features and Benefits:\n\nAnticonvulsant Action:\n\nSTARGAB 300 works by stabilizing electrical activity in the brain, making it an effective treatment for various types of seizures in patients with epilepsy. It helps reduce the frequency and severity of seizures, enhancing overall neurological stability.\nNeuropathic Pain Relief:\n\nGabapentin is particularly effective in managing neuropathic pain, which is pain caused by nerve damage. It helps reduce pain sensations, providing relief for conditions such as diabetic neuropathy, postherpetic neuralgia, and spinal cord injury-related pain.\nImproved Sleep Quality:\n\nPatients suffering from chronic pain often experience disrupted sleep. STARGAB 300 can improve sleep quality by alleviating pain, leading to better rest and overall well-being.\nMood Stabilization:\n\nIn addition to its primary uses, Gabapentin has been shown to have mood-stabilizing properties, making it beneficial for patients with mood disorders coexisting with neuropathic pain or epilepsy.\nWell-Tolerated and Safe:\n\nGabapentin is generally well-tolerated, with a favorable safety profile, making STARGAB 300 a reliable option for long-term management of neuropathic pain and seizures.\nDosage and Administration:\n\nInitial Dosage for Epilepsy:\n\nThe recommended starting dose of STARGAB 300 for epilepsy is 300mg once daily on the first day, 300mg twice daily on the second day, and 300mg three times daily on the third day. The dose can be gradually increased based on clinical response and tolerability, with a maintenance dose typically ranging from 900mg to 1800mg per day, divided into three doses.\nInitial Dosage for Neuropathic Pain:\n\nFor neuropathic pain, the initial dose is typically 300mg taken once daily, gradually increasing to 300mg three times daily, based on patient response and tolerability. The maintenance dose may range from 900mg to 3600mg per day, divided into multiple doses.\nAdministration Instructions:\n\nSTARGAB 300 tablets should be taken orally with or without food. It is advisable to take the medication at the same time each day to maintain consistent therapeutic levels in the bloodstream.\nContinued Monitoring:\n\nRegular monitoring of symptoms, pain levels, and potential side effects is essential during STARGAB 300 therapy to ensure therapeutic efficacy and patient safety.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order NOW\nhttps://www.sterisonline.com/product/stargab-300-134312", "price": 155.0, "discountamount": 46.5, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "mg", "rest", "life", "food", "brain", "EMAIL", "option", "epilepsy", "seizures", "addition", "symptoms", "severity", "Benefits", "patients", "same time", "first day", "third day", "frequency", "second day", "conditions", "Gabapentin", "medication", "information", "bloodstream", "pain levels", "three doses", "nerve damage", "Introduction", "sterispharma", "initial dose", "tolerability", "primary uses", "chronic pain", "Key Features", "sterisonline", "various types", "CALL/WHATSAPP", "starting dose", "multiple doses", "mood disorders", "patient safety", "Initial Dosage", "dosage strength", "pain sensations", "patient response", "maintenance dose", "clinical response", "Regular monitoring", "overall well-being", "Mood Stabilization", "STARGAB 300 tablets", "STARGAB 300 therapy", "electrical activity", "diabetic neuropathy", "effective treatment", "long-term management", "Continued Monitoring", "therapeutic efficacy", "Anticonvulsant Action", "neuropathic pain agent", "potential side effects", "postherpetic neuralgia", "Improved Sleep Quality", "Neuropathic Pain Relief", "favorable safety profile", "neurotransmitter release", "versatile anticonvulsant", "mood-stabilizing properties", "Administration Instructions", "consistent therapeutic levels", "overall neurological stability", "spinal cord injury-related pain" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1899, "imageuri": "https://productimages.withfloats.com/actual/666c020b8c6c791fd3b7131b.png", "tileimageuri": "https://productimages.withfloats.com/tile/666c020b8c6c791fd3b7131b.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-14T08:40:40.129Z", "updatedon": "2026-03-12T09:30:38.275Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//stargab-300-/1899", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "STARGAB 300 ", "category": "NEUROLOGY RANGE", "tags": [ "stargab 300 uses in hindi", "stargab 300 price in hindi", "gabapentin 300mg used for", "gabapentin 300mg dosage", "maximum dosage of gabapentin for nerve pain" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "666bff0d4cb45413344ec745", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Gabapentine 100mg", "description": "STERIS GABAPENTIN 100 \nGabapentine (100mg)\nIntroduction:\n\nSTERIS GABAPENTIN 100 contains Gabapentin, an anticonvulsant and neuropathic pain agent widely used to manage conditions such as epilepsy and neuropathic pain. With a dosage strength of 100mg, STERIS GABAPENTIN 100 aims to alleviate symptoms by modulating neurotransmitter release, thereby improving quality of life for patients.\nKey Features and Benefits:\n\nAnticonvulsant Action:\n\nSTERIS GABAPENTIN 100 works by stabilizing electrical activity in the brain, making it an effective treatment for various types of seizures in patients with epilepsy.\nNeuropathic Pain Relief:\n\nGabapentin is particularly effective in managing neuropathic pain, which is pain caused by nerve damage. It helps reduce pain sensations, providing relief for conditions such as diabetic neuropathy, postherpetic neuralgia, and spinal cord injury-related pain.\nImproved Sleep Quality:\n\nPatients suffering from chronic pain often experience disrupted sleep. STERIS GABAPENTIN 100 can improve sleep quality by alleviating pain, leading to better rest and overall well-being.\nMood Stabilization:\n\nIn addition to its primary uses, Gabapentin has been shown to have mood-stabilizing properties, making it beneficial for patients with mood disorders coexisting with neuropathic pain or epilepsy.\nWell-Tolerated and Safe:\n\nGabapentin is generally well-tolerated, with a favorable safety profile, making STERIS GABAPENTIN 100 a reliable option for long-term management of neuropathic pain and seizures.\nDosage and Administration:\n\nInitial Dosage for Epilepsy:\n\nThe recommended starting dose of STERIS GABAPENTIN 100 for epilepsy is 300mg on the first day, followed by 300mg twice daily on the second day, and 300mg three times daily on the third day. The dose can be gradually increased based on clinical response and tolerability.\nInitial Dosage for Neuropathic Pain:\n\nFor neuropathic pain, the initial dose is typically 100-300mg taken once daily, gradually increasing to 300mg three times daily based on patient response and tolerability.\nAdministration Instructions:\n\nSTERIS GABAPENTIN 100 tablets should be taken orally with or without food. It is advisable to take the medication at the same time each day to maintain consistent therapeutic levels in the bloodstream.\nContinued Monitoring:\n\nRegular monitoring of symptoms, pain levels, and potential side effects is essential during STERIS GABAPENTIN 100 therapy to ensure therapeutic efficacy and patient safety.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order NOW\n", "price": 85.0, "discountamount": 25.5, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "rest", "life", "food", "brain", "EMAIL", "300mg", "100mg", "option", "seizures", "addition", "symptoms", "Benefits", "patients", "epilepsy", "third day", "same time", "first day", "medication", "conditions", "second day", "Gabapentine", "information", "bloodstream", "pain levels", "nerve damage", "Introduction", "sterispharma", "initial dose", "tolerability", "chronic pain", "primary uses", "Key Features", "sterisonline", "CALL/WHATSAPP", "various types", "starting dose", "mood disorders", "Initial Dosage", "patient safety", "pain sensations", "dosage strength", "patient response", "clinical response", "Regular monitoring", "Mood Stabilization", "overall well-being", "electrical activity", "effective treatment", "diabetic neuropathy", "Continued Monitoring", "long-term management", "therapeutic efficacy", "Anticonvulsant Action", "Improved Sleep Quality", "neuropathic pain agent", "potential side effects", "postherpetic neuralgia", "Neuropathic Pain Relief", "neurotransmitter release", "favorable safety profile", "Administration Instructions", "mood-stabilizing properties", "STERIS GABAPENTIN 100 therapy", "STERIS GABAPENTIN 100 tablets", "consistent therapeutic levels", "spinal cord injury-related pain" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1898, "imageuri": "https://productimages.withfloats.com/actual/666bff128c6c791fd3b7123a.png", "tileimageuri": "https://productimages.withfloats.com/tile/666bff128c6c791fd3b7123a.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-14T08:27:57.94Z", "updatedon": "2026-03-14T10:15:22.493Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//gabapentine-100mg/1898", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "STERIS GABAPENTIN 100 ", "category": "NEUROLOGY RANGE", "tags": [ "normal dosage of gabapentin for nerve pain side ef", "maximum dose of gabapentin for adults", "gabapentin 100mg uses", "gabapentin a high dose", "uses of gabapentin capsules", "gabapentin 100mg" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6668429500e7d2232cab3cbd", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "aceclofenac pregabalin", "description": "PREGABRIAL ACP \nAceclofenac (SR) & Pregabalin (SR)\nIntroduction\nPREGABRIAL ACP is a combination medication that includes Aceclofenac (Sustained Release) and Pregabalin (Sustained Release). This dual-action formulation is designed to provide long-lasting relief from chronic pain and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, and neuropathic pain. By combining these two powerful agents, PREGABRIAL ACP offers comprehensive pain management, improving patients' quality of life.\n\nKey Ingredients and Their Benefits\nAceclofenac (SR)\nAnti-Inflammatory: Aceclofenac is a potent nonsteroidal anti-inflammatory drug (NSAID) that effectively reduces inflammation by inhibiting the enzyme cyclooxygenase (COX), which is involved in the synthesis of prostaglandins.\nPain Relief: It provides significant relief from pain associated with inflammatory conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.\nSustained Release: The sustained release formulation ensures a prolonged therapeutic effect, reducing the need for frequent dosing and maintaining consistent pain relief.\nPregabalin (SR)\nNeuropathic Pain Relief: Pregabalin is highly effective in reducing neuropathic pain, which is pain caused by nerve damage due to conditions like diabetes, shingles, or spinal cord injury.\nAnticonvulsant: It helps control partial seizures by reducing abnormal electrical activity in the brain, making it an important medication for epilepsy management.\nAnxiety Reduction: Pregabalin also has anxiolytic properties, making it beneficial for patients with generalized anxiety disorder (GAD).\nSustained Release: The sustained release formulation allows for consistent therapeutic levels, providing long-lasting relief from pain and reducing dosing frequency.\nBenefits of PREGABRIAL ACP\nComprehensive Pain Management: PREGABRIAL ACP combines the anti-inflammatory and pain-relieving properties of Aceclofenac with the neuropathic pain relief of Pregabalin, addressing multiple aspects of chronic pain.\nReduces Inflammation: Aceclofenac effectively reduces inflammation and swelling, promoting faster recovery and improved joint function.\nNeuropathic Pain Relief: Pregabalin targets nerve pain, providing significant relief from conditions such as diabetic neuropathy and post-herpetic neuralgia.\nProlonged Effect: The sustained release formulations ensure long-lasting pain relief, reducing the need for frequent dosing and maintaining consistent therapeutic levels.\nImproved Quality of Life: By managing pain and inflammation effectively, PREGABRIAL ACP helps improve mobility, function, and overall quality of life for patients with chronic pain conditions.\nDosage and Administration\nDosage\nRecommended Dosage: The typical dosage of PREGABRIAL ACP is one tablet taken once or twice daily, depending on the severity of the condition and the patient's response to treatment. The exact dosage should be determined by a healthcare provider.\nAdministration\nOral Use: Swallow the tablet whole with a full glass of water. It is best taken with food to reduce the risk of gastrointestinal discomfort.\nConsistency: For optimal results, take PREGABRIAL ACP at the same times each day to maintain an even level of the medication in your bloodstream.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order NOW\n", "price": 145.0, "discountamount": 44.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "SR", "GAD", "COX", "need", "even", "life", "risk", "food", "EMAIL", "NSAID", "water", "brain", "product", "severity", "Oral Use", "diabetes", "response", "Benefits", "shingles", "swelling", "mobility", "treatment", "synthesis", "nerve pain", "same times", "Pregabalin", "full glass", "one tablet", "Consistency", "bloodstream", "information", "Aceclofenac", "exact dosage", "sterisonline", "inflammation", "Introduction", "sterispharma", "nerve damage", "CALL/WHATSAPP", "Anticonvulsant", "prostaglandins", "PREGABRIAL ACP", "typical dosage", "osteoarthritis", "joint function", "faster recovery", "optimal results", "frequent dosing", "overall quality", "Key Ingredients", "Prolonged Effect", "Improved Quality", "partial seizures", "multiple aspects", "dosing frequency", "Anxiety Reduction", "patients' quality", "Recommended Dosage", "spinal cord injury", "significant relief", "two powerful agents", "healthcare provider", "diabetic neuropathy", "long-lasting relief", "epilepsy management", "important medication", "rheumatoid arthritis", "anxiolytic properties", "enzyme cyclooxygenase", "Administration Dosage", "combination medication", "consistent pain relief", "ankylosing spondylitis", "inflammatory conditions", "Neuropathic Pain Relief", "dual-action formulation", "chronic pain conditions", "post-herpetic neuralgia", "long-lasting pain relief", "pain-relieving properties", "gastrointestinal discomfort", "prolonged therapeutic effect", "generalized anxiety disorder", "abnormal electrical activity", "comprehensive pain management", "consistent therapeutic levels", "sustained release formulations", "potent nonsteroidal anti-inflammatory drug" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1742, "imageuri": "https://productimages.withfloats.com/actual/667d2b8e576e8da931df60d6.png", "tileimageuri": "https://productimages.withfloats.com/tile/667d2b8e576e8da931df60d6.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-11T12:27:01.285Z", "updatedon": "2026-03-14T11:16:12.471Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//aceclofenac-pregabalin/1742", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "PREGABRIAL ACP ", "category": "NEUROLOGY RANGE", "tags": [ "pregabrial acp dosage", "pregabrial acp uses in hindi", "pregabrial acp brands in india", "pregabrial acp manufacturers in india", "pregabrial acp ingredients", "neuropathic pain", "Pregabalin targets nerve pain" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6638740b71250f1e601ae6d8", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "STERISCOX PREGA", "description": "STERISCOX PREGA\nPregabalin SR & Etoricoxib Tab\n\"STERISCOX PREGA combines Pregabalin SR and Etoricoxib to manage neuropathic pain and reduce inflammation. Pregabalin targets nerve pain while Etoricoxib acts as an anti-inflammatory agent, providing comprehensive pain relief and enhanced mobility in conditions like arthritis.\"For further information:\nEmail: info@sterispharma.com / contact@sterispharma.com\nCall/WhatsApp: 7877551268, 7849827488\nOrder Now: \n", "price": 205.0, "discountamount": 62.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "mobility", "arthritis", "nerve pain", "conditions", "inflammation", "Pregabalin SR", "Etoricoxib Tab", "STERISCOX PREGA", "neuropathic pain", "anti-inflammatory agent", "comprehensive pain relief" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1117, "imageuri": "https://productimages.withfloats.com/actual/6638740dfa384161ec318a8c.png", "tileimageuri": "https://productimages.withfloats.com/tile/6638740dfa384161ec318a8c.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-05-06T06:09:15.437Z", "updatedon": "2026-03-16T07:02:08.099Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//steriscox-prega/1117", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Pregabalin SR & Etoricoxib Tab", "category": "ORTHOLOGYRANG", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6abe4471401ae1a1106d67d9", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Bisoprolol 1.25mg", "description": "Bisoprolol 1.25mg is the smallest tablet strength of bisoprolol, a heart-selective beta-1 blocker. Doctors usually prescribe it to start treatment or to build up the dose gradually in people with high blood pressure, chronic stable heart failure, or fast heart rhythms. It suits older adults, people with mild heart failure, and anyone who reacts strongly to beta-blockers. The medicine slows the heartbeat and eases the force of each contraction, so the heart works less hard. BISOGARD 1.25 from Steris Healthcare Pvt. Ltd. comes in a strip pack of 15 tablets. It is a Schedule H medicine, so it must only be started, changed, or stopped on a doctor's advice.\n\nProduct Snapshot\n\nBrand: BISOGARD 1.25\nManufacturer/Marketer: Steris Healthcare Pvt. Ltd., a WHO-GMP and ISO-certified pharmaceutical company in India\nActive ingredient: Bisoprolol Fumarate 1.25mg\nForm: Tablet\nPack size: 15 tablets\nDrug class: Cardioselective beta-1 blocker\nLegal status: Schedule H (valid prescription required)\nAvailability: Through Steris Healthcare's authorized pharmacies and its B2B PCD franchise network across India\nWhat Is Bisoprolol 1.25mg?\n\nIf your doctor has just prescribed bisoprolol 1.25mg, you have been given the lowest dose on purpose. Bisoprolol is a cardioselective beta-1 blocker, meaning it acts mostly on receptors in the heart and has much less effect on the lungs and blood vessels. This is a major reason it is preferred over older, non-selective beta-blockers, especially for people who also have a mild breathing problem.\n\nThe 1.25mg tablet is not a “light” medicine for mild illness. It is a carefully chosen entry point. In heart failure, a weakened heart can struggle if its rate or pressure drops too quickly, so cardiologists follow a “start low, go slow” approach. Treatment begins at 1.25mg, the response is watched for one to two weeks, and the dose is raised step by step (commonly 2.5mg, 3.75mg, 5mg, 7.5mg, and up to 10mg) as the heart adapts. That is why BISOGARD 1.25 is often the first tablet a newly diagnosed heart failure patient takes.\n\nWhat Is Bisoprolol 1.25mg Used For?\n\nDoctors commonly prescribe this strength for:\n\nChronic heart failure (HFrEF): as the first step of dose titration in patients with a reduced ejection fraction, alongside ACE inhibitors/ARBs and diuretics\nHigh blood pressure: especially in older adults, people with low body weight, and those who are sensitive to blood-pressure-lowering drugs\nStable angina: to reduce the heart's oxygen demand and relieve chest discomfort\nAfter a heart attack: in selected patients, under a cardiologist's care\nHeart rate control in some arrhythmias: sometimes used off-label at a low dose to gently bring down a fast heart rate\n\nAt 1.25mg, bisoprolol is seldom meant as the long-term sole treatment for high blood pressure in an otherwise healthy adult. It is usually the first rung of a titration ladder, or a steady maintenance dose for patients who are unusually beta-blocker sensitive (older age, low body weight, or borderline low pressure or pulse).\n\nHow Does Bisoprolol Work?\n\nBisoprolol selectively blocks beta-1 adrenergic receptors, which are packed mainly into heart muscle. This leads to several effects:\n\nSlower heart rate: the heart has more time to fill and rest between beats\nGentler contractions: the heart muscle needs less oxygen and energy\nLess renin from the kidneys: this helps blood pressure fall gradually over time\nLower overall cardiac workload: a real advantage for a heart that already struggles to pump well, as in heart failure\nKey Benefits of BISOGARD 1.25\nA gentle starting dose, well suited to careful titration in frail or elderly patients\nHeart-focused action, with less effect on the lungs and peripheral blood vessels than non-selective beta-blockers\nOnce-daily dosing, which makes it easier to stay on treatment\nA guideline-recommended beta-blocker for HFrEF with well-established outcomes data [Reviewer note: insert specific outcome statistics/trial citation pending medical sign-off]\nMade by Steris Healthcare Pvt. Ltd. under WHO-GMP and ISO-certified standards\nDosage Guidance\nUsual starting dose (heart failure): 1.25mg once a day, preferably in the morning\nDose increases: typically every 1–2 weeks (2.5mg, 3.75mg, 5mg, 7.5mg, up to a maximum of 10mg daily), depending on how well you tolerate it and on your pulse and blood pressure\nHigh blood pressure (sensitive patients): 1.25mg to 5mg once daily, as set by your doctor\nHow to take it: at the same time every day, with or without food, swallowed whole with water\nIf you miss a dose: take it when you remember, unless the next dose is almost due. Never take a double dose.\nNever stop suddenly: abrupt withdrawal can cause a rebound rise in heart rate, blood pressure, or chest pain. The dose must be reduced gradually under medical supervision.\nIs It Better to Take Bisoprolol in the Morning or at Night?\n\nMost doctors advise a morning dose. Bisoprolol lowers pulse and blood pressure, and taking it early matches its action to your daytime activity. A night-time dose could add to the body's natural overnight dip in blood pressure and raise the chance of dizziness when getting up in the dark. Some people who feel tired during the day are told by their doctor to switch to the evening. Do not change your dosing time without your doctor's approval.\n\nSide Effects of Bisoprolol 1.25mg\n\nCommon side effects\n\nTiredness or fatigue\nDizziness or light-headedness, especially on standing quickly\nCold hands or feet\nSlow pulse (bradycardia)\nHeadache\nMild stomach upset (nausea, loose stools)\nDisturbed sleep\n\nSerious side effects (get medical help promptly)\n\nVery slow heartbeat or fainting\nIncreasing breathlessness or swollen legs/ankles, which may mean heart failure is worsening\nAllergic reaction: rash, swelling of the face or throat, trouble breathing\nCold, numb, or bluish fingers and toes\nWheezing or new breathing difficulty, particularly in people with asthma or COPD\nMood changes, low mood, or confusion\nWhat Are the Bad Side Effects of Bisoprolol?\n\nThe effects that need urgent attention are a dangerously slow pulse, fainting, signs of worsening heart failure (swelling, breathlessness), severe allergic reactions, and airway tightening in people with lung disease. These are uncommon at the 1.25mg dose, but anyone who notices them should seek medical help right away. [Reviewer note: specific incidence rates pending clinical/medical sign-off]\n\nSubstitutes & Comparable Beta-Blockers\nMolecule\tSelectivity\tTypical Use Case\nBisoprolol\tHighly cardioselective\tHeart failure titration, hypertension\nMetoprolol Succinate ER\tCardioselective\tHypertension, angina, heart failure\nAtenolol\tCardioselective (older agent)\tHypertension\nCarvedilol\tNon-selective with alpha-blocking action\tHeart failure (adds vasodilation)\nPropranolol\tNon-selective\tMigraine prevention, anxiety-related fast heartbeat, essential tremor\nPrecautions & Who Should Avoid Bisoprolol\nNot suitable for people with severe bradycardia, certain forms of heart block (unless a pacemaker is fitted), unstable or acutely decompensated heart failure, or severe uncontrolled asthma\nUse carefully in diabetes, because beta-blockers can hide the warning signs of low blood sugar\nTake care in peripheral vascular disease, as cold extremities or leg pain on walking may worsen\nNever stop it abruptly; always taper under a doctor's guidance\nTell your doctor about every medicine you use, especially other blood-pressure drugs, calcium channel blockers, and certain antiarrhythmics\nIn pregnancy and breastfeeding, use only if your doctor advises it after weighing benefits and risks\nIs Bisoprolol Safe for Kidneys?\n\nThe body clears bisoprolol through both the liver and the kidneys in roughly equal measure. It is generally considered safe for people with normal or mildly reduced kidney function. When kidney impairment is significant, drug levels in the blood can rise, so your doctor may lower the dose or monitor you more closely. Always tell your prescriber about any kidney disease before starting.\n\nIs Bisoprolol a High-Risk Medication?\n\nBisoprolol is not a narrow therapeutic index drug like tacrolimus or warfarin, where small dose differences matter greatly. Even so, it needs supervised use because it directly affects heart rate and blood pressure. The main dangers are stopping it suddenly, which can set off rebound cardiac events, and using it with certain existing rhythm disorders. Taken as prescribed and checked regularly, it has a long and reassuring safety record.\n\nDoes 1.25mg Bisoprolol Lower Blood Pressure?\n\nYes. Even the smallest dose measurably reduces heart rate and blood pressure by lightening the heart's workload and reducing renin-driven narrowing of blood vessels. At this strength the effect on blood pressure is fairly mild, which is exactly why it is a safe place to begin, especially for older adults or people starting heart failure treatment. The dose is then raised gradually to reach full benefit.\n\nFrequently Asked Questions\n\n1. What is 1.25 mg of bisoprolol used for?\nMainly as a low starting dose when building up treatment for chronic heart failure, and for high blood pressure in people who are very sensitive to beta-blockers, such as older adults.\n\n2. What are the bad side effects of bisoprolol?\nThe more serious ones are a very slow pulse, fainting, worsening heart failure signs (swelling, breathlessness), severe allergy, and breathing trouble in people with lung conditions.\n\n3. What are the common side effects of bisoprolol fumarate 1.25 mg tablets?\nTiredness, dizziness, cold hands and feet, mild headache, and a slightly slower pulse.\n\n4. Is it better to take bisoprolol in the morning or at night?\nMorning is usually preferred so its effect fits daytime activity, though your doctor may suggest evenings in some cases.\n\n5. What is the cost of bisoprolol?\nPrice depends on strength, pack size, and brand. Use the “Check Price” option above for current BISOGARD 1.25 pricing from Steris Healthcare.\n\n6. Does 1.25 mg bisoprolol lower blood pressure?\nYes, though only modestly at this dose. The dose is often stepped up over time.\n\n7. Is bisoprolol safe for kidneys?\nGenerally yes for normal or mildly reduced kidney function. People with significant kidney impairment need dose adjustment and monitoring.\n\n8. Is bisoprolol a high-risk medication?\nIt is not a narrow therapeutic index drug, but it must never be stopped suddenly and should be used under medical supervision because of its direct effect on the heart.\n\n9. Can I take bisoprolol 1.25mg for the rest of my life?\nMany people with chronic heart failure or hypertension do take bisoprolol long term, but the dose usually rises as tolerated. Your doctor should review it regularly.\n\n10. What happens if I miss a dose of bisoprolol?\nTake it when you remember, unless the next dose is nearly due. In that case skip the missed one. Never take two together.\n\n11. Can bisoprolol 1.25mg cause weight gain?\nIt is not commonly reported at this dose. Fluid retention linked to heart failure itself should be reported to your doctor.\n\n12. Is bisoprolol safe for diabetic patients?\nIt can be used, with care, because beta-blockers may hide warning signs of low blood sugar such as a racing heartbeat.\n\n13. Can I stop taking bisoprolol suddenly if I feel fine?\nNo. Stopping abruptly can cause a rebound rise in heart rate, blood pressure, or chest pain. Reduce the dose gradually under medical guidance.\n\n14. Does bisoprolol interact with other blood pressure medicines?\nYes. Combining it with other drugs that lower heart rate or pressure (such as calcium channel blockers) can cause a very low pulse or pressure. Tell your doctor about all your medicines.\n\n15. Is BISOGARD 1.25 available without a prescription?\nNo. Bisoprolol is a Schedule H medicine in India and needs a valid prescription.\n\n16. How long does it take for bisoprolol 1.25mg to start working?\nSome effect on heart rate appears within hours, but the full benefit for blood pressure or heart failure symptoms builds over several weeks of regular use.\n\n17. Can pregnant women take bisoprolol?\nOnly if clearly necessary and prescribed by a doctor, as it may affect the baby's heart rate and growth.", "price": 39.0, "discountamount": 12.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2501, "imageuri": "https://productimages.withfloats.com/actual/6abe4474c205678e0b16a23a.png", "tileimageuri": "https://productimages.withfloats.com/tile/6abe4474c205678e0b16a23a.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-10-01T11:30:57.88Z", "updatedon": "2026-10-01T11:30:57.88Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//bisoprolol-1-25mg/2501", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Bisogard 1.25", "category": "CARDIOLOGYRANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6a86e496cc4491de1ed77dfd", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Etoricoxib & Cyclobenzaprine Hydrochloride Tablets", "description": "ERITOCOX BENZ 90/5 is a fixed-dose combination tablet pairing Etoricoxib 90 mg, a selective COX-2 anti-inflammatory, with Cyclobenzaprine Hydrochloride 5 mg, a centrally acting muscle relaxant. It is prescribed for short-term relief of acute musculoskeletal problems where pain, swelling, and muscle tightness occur together — think a sudden low-back strain, a stiff neck, or a flare-up of arthritis where the surrounding muscles clamp down defensively. Rather than treating the inflammation alone or the spasm alone, this tablet addresses both mechanisms in one dose, which can mean fewer pills and a more complete response for short, acute episodes. It is a prescription-only (Schedule H) medicine, produced under WHO-GMP and ISO-certified manufacturing standards by Steris Healthcare Pvt. Ltd. Typical side effects include drowsiness, dry mouth, and mild stomach upset; because the combination carries cardiovascular, gastrointestinal, and kidney considerations, it should only be used under a doctor's supervision. This page walks through what the tablet does, how it works, correct usage, safety information, and answers to the questions people most often ask.\n\nWhat Is ERITOCOX BENZ 90/5?\n\nPain from an acute back injury, a wrenched neck, or an arthritis episode almost never travels alone — it tends to bring a tense, guarded muscle along with it that makes every movement feel worse. ERITOCOX BENZ 90/5 was formulated with that pattern in mind, folding two separate mechanisms into a single tablet rather than requiring two prescriptions.\n\nActive Ingredient\tStrength\tRole\nEtoricoxib\t90 mg\tSelective COX-2 inhibitor for inflammatory pain\nCyclobenzaprine Hydrochloride\t5 mg\tCentrally acting skeletal muscle relaxant\n\nEach tablet is manufactured by Steris Healthcare Pvt. Ltd., a WHO-GMP and ISO-certified pharmaceutical company, so every batch meets verified potency and quality benchmarks.\n\nWhy This Combination Makes Sense\n\nMusculoskeletal pain is rarely a single-track problem. When tissue is injured or irritated, inflammation flares up locally — and nearby muscles frequently respond by tightening protectively. That protective tightening, the spasm, often becomes a pain generator of its own. Treat only the inflammation and the spasm can linger; treat only the spasm and the underlying inflammation keeps driving discomfort.\n\nERITOCOX BENZ 90/5 is built to intervene on both fronts at once:\n\nEtoricoxib addresses the chemical cascade responsible for pain and swelling at the injured site.\nCyclobenzaprine works through the central nervous system to calm the muscle guarding that so often rides alongside that pain.\nMechanism of Action: How ERITOCOX BENZ 90/5 Works\n\nEtoricoxib selectively inhibits the COX-2 enzyme — the enzyme the body ramps up at sites of tissue damage or irritation to manufacture prostaglandins, the chemical messengers behind pain, swelling, and localized heat. Because it targets COX-2 specifically rather than blocking both COX-1 and COX-2 the way older, non-selective NSAIDs do, etoricoxib is designed to control inflammatory pain while leaving more of the COX-1 activity that protects the stomach lining relatively undisturbed.\n\nCyclobenzaprine Hydrochloride takes a different route entirely — its primary site of action is the brainstem, not the muscle fiber itself. By dampening excessive motor signaling sent to skeletal muscle, it reduces spasm and stiffness without producing the broad muscle weakness that a directly-acting muscle agent might cause.\n\nPut together, the tablet delivers a two-pronged effect: peripheral anti-inflammatory action from etoricoxib, layered with central muscle relaxation from cyclobenzaprine.\n\n[Reviewer placeholder: insert verified pharmacokinetic data (onset, half-life, bioavailability) once confirmed by medical/regulatory team — do not publish unverified figures.]\n\nClinical Uses of ERITOCOX BENZ 90/5\n\nA physician may prescribe this combination for short-term management of acute conditions where pain, inflammation, and spasm show up together, including:\n\nCondition\tTypical Presentation\nAcute lower back pain\tPain with associated muscle guarding/spasm\nNeck strain / cervical spasm\tStiff, restricted neck movement\nSprains, strains, overuse injuries\tMusculoskeletal trauma with inflammatory pain\nOsteoarthritis flare-ups\tJoint pain accompanied by surrounding muscle tightness\nPostural or occupational muscle pain\tWork- or posture-related inflammation and tension\nMovement restriction linked to spasm\tReduced range of motion driven by muscular guarding\n\nSuitability for any of the above must be confirmed by a doctor based on your specific diagnosis and medical history.\n\nKey Benefits of ERITOCOX BENZ 90/5\nOne tablet, two mechanisms — anti-inflammatory pain relief and muscle-spasm relief combined, simplifying an otherwise two-drug regimen.\nSite-focused inflammation control — etoricoxib's COX-2 selectivity is intended to concentrate its effect where inflammation is actually active.\nA comparatively gentler GI footprint — COX-2-selective action is generally linked to lower gastrointestinal irritation risk than older non-selective NSAIDs, though vigilance is still warranted.\nLoosens spasm-related stiffness — cyclobenzaprine's central action helps release tight, guarded muscles restricting movement.\nAids functional recovery — easing both pain and spasm can make it more realistic to resume light activity, stretching, or physiotherapy once your doctor clears you.\nStreamlined short-course dosing — a once-daily schedule (as prescribed) cuts down pill burden versus taking an NSAID and a muscle relaxant separately.\nDosage & Administration\n\nThe following is general reference information — your doctor's specific prescription always takes precedence.\n\nTake ERITOCOX BENZ 90/5 exactly as prescribed, generally once a day, with or without food.\nSwallow the tablet whole with water; avoid crushing or chewing unless your doctor tells you otherwise.\nTreatment is typically short — anywhere from a few days to roughly two weeks — reflecting the acute, self-limiting nature of most pain-and-spasm episodes.\nIf a dose is missed, take it as soon as you remember, but skip it entirely if the next dose is nearly due. Never double up to make up for a missed dose.\nDo not extend the treatment period or adjust your dose independently, even if symptoms haven't fully resolved.\nSide Effects of ERITOCOX BENZ 90/5\nCommon Side Effects\nDrowsiness or sleepiness\nDizziness\nDry mouth\nHeadache\nStomach discomfort or indigestion\nNausea\nFatigue\nMild elevation in blood pressure in some individuals\nSerious Side Effects — Seek Medical Help Promptly\nSigns of gastrointestinal bleeding, such as black stools or vomiting blood\nA severe allergic reaction — swelling of the face or throat, breathing difficulty, or widespread rash\nChest pain, irregular heartbeat, or other symptoms suggestive of a cardiovascular event\nYellowing of the skin or eyes, which may point to liver involvement\nA noticeable drop in urine output, which may suggest kidney impairment\nSevere dizziness, confusion, or fainting\n\nIf any of these serious symptoms appear, stop the medicine and get medical attention immediately.\n\nPrecautions & Warnings\nShare your full medical history with your doctor before starting, including any heart, kidney, or liver conditions.\nUse cautiously — or avoid altogether — if you have a history of stomach ulcers or gastrointestinal bleeding.\nGenerally not advised for people with uncontrolled high blood pressure, existing heart disease, or a prior stroke, unless a doctor specifically clears its use.\nSteer clear of alcohol, since it can amplify cyclobenzaprine's sedative effect and add to gastrointestinal risk.\nCyclobenzaprine may cause drowsiness or dizziness — hold off on driving or operating machinery until you know how the tablet affects you.\nDon't combine ERITOCOX BENZ 90/5 with other NSAIDs, painkillers, or sedating medicines without checking with your doctor first.\nAvoid the medicine if you have known hypersensitivity to etoricoxib, cyclobenzaprine, or related compounds.\nNot generally recommended during pregnancy or breastfeeding unless a doctor specifically advises otherwise.\nAvoid combining with MAO inhibitors, or using shortly after stopping them.\nDrug Interactions to Flag With Your Doctor\n\nDisclose every prescription medicine, over-the-counter product, and supplement you take. Extra caution is needed around medicines affecting:\n\nBlood pressure regulation\nKidney function\nBlood clotting\nCentral nervous system activity (sedatives, other muscle relaxants)\nLiver metabolism\nOther anti-inflammatory or pain-relief medicines\nConclusion\n\nERITOCOX BENZ 90/5 brings Etoricoxib 90 mg and Cyclobenzaprine Hydrochloride 5 mg together to tackle a problem that rarely presents as a single issue — pain, inflammation, and muscle spasm that reinforce one another in acute musculoskeletal conditions. By acting on both the inflammatory and muscular sides of that cycle, it offers a more rounded short-term response than either ingredient could provide alone.\n\nGiven the genuine cardiovascular, gastrointestinal, kidney, and central-nervous-system considerations involved, ERITOCOX BENZ 90/5 is meant strictly for short, doctor-supervised courses — not casual or extended self-treatment. Always check with your doctor to confirm whether this combination is right for your condition, medical history, and current medications.\n\nPrescription only – consult your doctor.\n\nFrequently Asked Questions (Google & AI Mode / Voice Search Optimized)\n\n1. What is ERITOCOX BENZ 90/5 used for? It's typically prescribed for short-term relief of acute musculoskeletal issues — such as back pain, neck strain, or an arthritis flare-up — where pain, inflammation, and muscle spasm show up together.\n\n2. Is ERITOCOX BENZ 90/5 a muscle relaxant? It's a combination tablet: the muscle-relaxing effect comes from its Cyclobenzaprine Hydrochloride component, while Etoricoxib supplies the pain-relieving, anti-inflammatory action.\n\n3. Is Etoricoxib a strong painkiller? Etoricoxib is an effective selective COX-2 inhibitor typically used for moderate inflammation-related pain, such as arthritis or an acute musculoskeletal injury. Its appropriateness for your level of pain should be assessed by a doctor.\n\n4. Is Etoricoxib safe for the kidneys? As with other NSAIDs, etoricoxib can influence kidney function, particularly with extended use, higher doses, dehydration, or existing kidney disease. It should be used carefully and only under medical guidance if kidney health is a concern.\n\n5. Should ERITOCOX BENZ 90/5 be taken in the morning or at night? It's usually taken once a day at a time your doctor sets. Since cyclobenzaprine can cause drowsiness, many doctors lean toward an evening dose — but always stick to your specific prescription.\n\n6. What are the common side effects of ERITOCOX BENZ 90/5? Frequently reported effects include drowsiness, dizziness, dry mouth, headache, stomach discomfort, and mild fatigue. Most fade on their own, but persistent symptoms should be reported to your doctor.\n\n7. How fast does ERITOCOX BENZ 90/5 start working? Etoricoxib tends to absorb fairly quickly, and many people feel pain relief within roughly an hour, though onset can vary by individual and whether the tablet is taken with food.\n\n8. What should be avoided while on ERITOCOX BENZ 90/5? Skip alcohol, avoid taking other NSAIDs or painkillers without medical advice, and hold off on driving or operating machinery if you're feeling drowsy or dizzy.\n\n9. How many days can ERITOCOX BENZ 90/5 be taken? It's usually prescribed for a short stretch — a few days up to around two weeks — matching how acute conditions typically resolve. Anything longer needs your doctor's review.\n\n10. What are the benefits of ERITOCOX BENZ 90/5? It delivers combined relief from pain, inflammation, and muscle spasm in one tablet, which can make it easier to move normally and get back to daily activity sooner when used as directed.\n\n11. How safe is ERITOCOX BENZ 90/5? Taken exactly as prescribed and for the recommended duration, it's generally considered safe for most adults. It does carry cardiovascular, gastrointestinal, kidney, and liver-related risks that call for medical supervision, especially if you already have related conditions.\n\n12. Can ERITOCOX BENZ 90/5 be used for knee pain? Yes — its etoricoxib component is commonly used for joint pain tied to osteoarthritis or an acute injury, including the knee, by reducing the underlying inflammation. A doctor should confirm suitability first.\n\n13. Does ERITOCOX BENZ 90/5 cause drowsiness? Yes — drowsiness and dizziness are known effects linked to its cyclobenzaprine component. Avoid driving or tasks requiring full alertness until you know how it affects you.\n\n14. Can ERITOCOX BENZ 90/5 be bought without a prescription? No. This is a prescription-only medicine meant to be taken solely under a qualified doctor's supervision — it isn't meant for self-prescribing or extended use without medical oversight.\n\n15. Can ERITOCOX BENZ 90/5 be taken with food? It can generally be taken with or without food, though taking it with food may ease stomach discomfort for some people. Follow your doctor's specific instructions.\n\n16. Is ERITOCOX BENZ 90/5 habit-forming? Cyclobenzaprine isn't considered addictive with typical short-term use, but the tablet should still be taken only for the prescribed duration and not restarted on your own without medical advice.\n\n17. Who should avoid taking ERITOCOX BENZ 90/5? 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By uniting a centrally acting muscle relaxant with a proven analgesic, this film-coated tablet addresses both the neurological and physical aspects of muscle strain, restoring movement and facilitating recovery.\n\nActive Ingredients\nEach film-coated tablet contains:\n\nTolperisone Hydrochloride (150 mg): A muscle relaxant targeting involuntary contractions within the central nervous system.\n\nParacetamol (325 mg): A widely recognized analgesic and antipyretic agent that blocks pain signal transmission.\n\nAvailable in blister packaging and dispensed strictly under a licensed physician's order.\n\nTherapeutic Mechanism\nPainful muscle conditions often create a feedback loop where localized pain triggers involuntary spasms, which in turn exacerbate the pain. TOPERITIME P 150/325 disrupts this cycle through a two-pronged mechanism:\n\nNeuromuscular Regulation: Tolperisone Hydrochloride acts on the spinal cord and brainstem reflexes to inhibit hyperactive nerve impulses driving muscle tension. Unlike traditional skeletal muscle relaxants, it achieves this with minimal central nervous system depression, significantly reducing the likelihood of heavy sedation.\n\nNociceptive Blocking: Paracetamol inhibits prostaglandin synthesis within the central nervous system, raising the body's overall pain threshold and attenuating pain signals originating from injured tissues.\n\nBy simultaneously relaxing tight muscle fibers and dampening pain sensation, the formulation provides comprehensive symptomatic relief.\n\nClinical Indications\nHealthcare professionals may prescribe TOPERITIME P 150/325 for various acute and subacute conditions characterized by pain and hypertonia, including:\n\nAcute muscle spasms and athletic injuries\n\nAcute or chronic lower back pain (lumbago)\n\nCervical spine discomfort and stiff neck\n\nCervical and lumbar spondylosis\n\nFrozen shoulder (adhesive capsulitis)\n\nPost-operative or post-traumatic muscle recovery\n\nGeneralized connective tissue or orthopedic pain\n\nKey Clinical Features\nBalanced Dual Action: Simultaneously targets involuntary contractions and pain sensation.\n\nLow-Sedation Profile: Tolperisone allows patients to maintain daily function without severe daytime drowsiness typical of older relaxants.\n\nEnhanced Mobility: Reduces joint and tissue stiffness, enabling better engagement in physical rehabilitation.\n\nStreamlined Regimen: Combines two therapeutic agents into a single convenient dosage form.\n\nUsage Guidelines\nThis medication must be taken strictly in accordance with a medical prescription.\n\nAdministration: Swallow the tablet whole with water. Do not crush, chew, or split the film-coated tablet.\n\nTiming: Take immediately after a meal to reduce potential gastrointestinal upset, unless directed otherwise by a doctor.\n\nCompliance: Complete the full course prescribed by your physician, and do not alter the recommended dosage.\n\nPotential Side Effects\nWhile generally well-tolerated, some individuals may experience mild side effects, including:\n\nGastrointestinal distress or mild nausea\n\nTransient dizziness or lightheadedness\n\nHeadaches\n\nGeneral fatigue or muscular weakness\n\nRare: Hypersensitivity reactions or cutaneous skin rashes (discontinue use and consult a physician immediately if severe symptoms appear).\n\nSafety Precautions and Considerations\nConsult a medical practitioner prior to initiating treatment if any of the following apply:\n\nPre-existing hepatic (liver) or renal (kidney) impairment\n\nKnown hypersensitivity to Tolperisone, Paracetamol, or related compounds\n\nPregnancy, plans for pregnancy, or active breastfeeding\n\nHistory of chronic alcohol dependency (due to increased liver sensitivity with Paracetamol)\n\nConcurrent use of other medications, particularly other products containing Paracetamol or central nervous system depressants\n\nStorage and Handling\nStore in a cool, dry area below 25°C (77°F).\n\nProtect from direct light, heat, and moisture.\n\nKeep strictly out of reach of children and pets.\n\nCheck the packaging expiration date before administration.\n\nFrequently Asked Questions\nWhat primary conditions does TOPERITIME P 150/325 treat?\n\nIt is indicated for short-term relief from acute musculoskeletal pain, muscle spasms, neck strains, backaches, and related orthopedic disorders.\n\nWhy is Tolperisone combined with Paracetamol?\n\nTolperisone eases muscle tightness at the neurological level, while Paracetamol lowers overall pain perception, creating a synergistic effect that addresses both spasm and pain together.\n\nWill this medication cause severe drowsiness?\n\nTolperisone is specifically designed to exert less sedating activity compared to older muscle relaxants. 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