Home> Products> metformin 500 mg mechanism of action

{ "products": [ { "_id": "665ef17474d94b15a06c31e2", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "gliclazide 40mg metformin 500 mg", "description": "GLICLAGLAZE M 40 \ngliclazide 40mg metformin 500 mg\nIntroduction\nGLICLAGLAZE M 40 is a combination medication designed to manage blood sugar levels in individuals with Type 2 diabetes. This oral treatment integrates two potent antidiabetic agents: Gliclazide (40 mg) and Metformin (500 mg), each playing a crucial role in diabetes control.\n\nHow It Works\n\nGliclazide (40 mg): As a sulfonylurea, Gliclazide works by stimulating the release of insulin from the pancreatic beta cells. Insulin is the hormone responsible for reducing blood glucose levels. Gliclazide also enhances the sensitivity of peripheral tissues to insulin and reduces the likelihood of clot formation, which is a common complication in diabetes patients.\nMetformin (500 mg): Metformin acts primarily by reducing glucose production in the liver. It also improves insulin sensitivity, enhancing peripheral glucose uptake and utilization. Unlike many other antidiabetic medications, Metformin does not cause hypoglycemia (low blood sugar) and is often associated with weight loss.\nBenefits\nThe dual mechanism of GLICLAGLAZE M 40 offers a comprehensive approach to diabetes management by not only improving insulin production and sensitivity but also addressing the hepatic release of glucose. This combination reduces blood sugar levels effectively while minimizing the risk of side effects common to other diabetes treatments, such as hypoglycemia.\n\nUsage Guidelines\n\nDosage: Typically, the initial dosage is guided by the patient’s current treatment regimen, effectiveness, and tolerability. Adjustment in dosage should be made based on the patient’s blood glucose response, under the supervision of a healthcare provider.\nAdministration: GLICLAGLAZE M 40 should be taken with meals to reduce gastrointestinal side effects and to enhance absorption.\nSide Effects\nWhile GLICLAGLAZE M 40 is generally well-tolerated, it may cause some side effects. Common ones include gastrointestinal disturbances such as nausea and diarrhea, which are often transient. Hypoglycemia may occur, but it is less frequent due to the mitigating action of Metformin.\n\nConclusion\nGLICLAGLAZE M 40 is a cornerstone in the pharmacological treatment of Type 2 diabetes, offering benefits derived from the combined effects of Gliclazide and Metformin. It is essential for patients to follow their healthcare provider’s instructions and to maintain regular check-ups to optimize treatment outcomes and prevent complications. This medication enables patients to manage their diabetes more effectively and improve their quality of life.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n Order Now\n\n\n\n\n\n\n\n", "price": 149.0, "discountamount": 44.7, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "life", "risk", "liver", "meals", "40 mg", "Order", "EMAIL", "500 mg", "nausea", "quality", "hormone", "diarrhea", "Benefits", "Metformin", "gliclazide", "Adjustment", "likelihood", "Conclusion", "absorption", "utilization", "cornerstone", "information", "supervision", "individuals", "weight loss", "sulfonylurea", "hypoglycemia", "Introduction", "tolerability", "sterisonline", "instructions", "sterispharma", "crucial role", "complications", "GLICLAGLAZE M", "CALL/WHATSAPP", "effectiveness", "oral treatment", "dual mechanism", "clot formation", "Administration", "initial dosage", "Type 2 diabetes", "hepatic release", "low blood sugar", "diabetes control", "combined effects", "mitigating action", "diabetes patients", "regular check-ups", "blood sugar levels", "treatment outcomes", "peripheral tissues", "glucose production", "insulin production", "diabetes management", "insulin sensitivity", "common complication", "healthcare provider", "blood glucose levels", "pancreatic beta cells", "combination medication", "blood glucose response", "comprehensive approach", "Usage Guidelines Dosage", "pharmacological treatment", "peripheral glucose uptake", "current treatment regimen", "other diabetes treatments", "gastrointestinal disturbances", "gastrointestinal side effects", "two potent antidiabetic agents", "many other antidiabetic medications" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1284, "imageuri": "https://productimages.withfloats.com/actual/665ef175c06ee12d88caa810.png", "tileimageuri": "https://productimages.withfloats.com/tile/665ef175c06ee12d88caa810.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-04T10:50:28.577Z", "updatedon": "2026-03-13T05:35:17.063Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/gliclazide-40mg-metformin-500-mg/1284", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "GLICLAGLAZE M 40 ", "category": "DIABETIC RANGE", "tags": [ "gliclazide 40mg metformin 500 mg tablet uses", "gliclazide 40mg metformin 500 mg dosage for diabetes", "gliclazide metformin 40 mg 500 mg side effects", "gliclazide 40mg metformin 500 mg tablet for type 2 diabetes", "gliclazide metformin combination tablet information", "gliclazide metformin 40mg 500mg blood sugar control", "buy gliclazide 40mg metformin 500 mg tablets online", "order gliclazide metformin tablets online india", "gliclazide metformin bulk purchase online", "gliclazide 40mg metformin 500 mg uses dosage and side effects", "buy gliclazide 40mg metformin 500 mg tablets online best price", "gliclazide 40mg metformin 500 mg price in india" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "665eef7e4515df174861ed41", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "glibenclamide 5mg metformin 500mg", "description": "GLIBEMIDE FORTE \nGLIBEMIDE FORTE is a combination oral antidiabetic medication formulated with 5 mg of Glibenclamide and 500 mg of Metformin. This dual-action medicine is designed to help individuals manage blood glucose levels effectively in the treatment of Type 2 Diabetes. By combining two well-established diabetes medications, GLIBEMIDE FORTE works through complementary mechanisms to improve overall blood sugar control.\n\nManaging diabetes requires a balanced approach that includes medication, diet, exercise, and regular monitoring of blood sugar levels. GLIBEMIDE FORTE is often prescribed when lifestyle changes and a single medication are not enough to achieve optimal glycemic control. The combination of glibenclamide and metformin provides a more comprehensive strategy for controlling blood sugar by addressing both insulin production and insulin sensitivity.\n\nThis medication is commonly recommended for adults with Type 2 diabetes who require a stronger treatment approach to maintain stable glucose levels and prevent long-term complications associated with uncontrolled diabetes.\n\nHow GLIBEMIDE FORTE Works\n\nGLIBEMIDE FORTE contains two active ingredients that work together to regulate blood sugar levels.\n\nRole of Glibenclamide\n\nGlibenclamide belongs to a class of medicines known as sulfonylureas. It works by stimulating the pancreas to release more insulin. Insulin is the hormone responsible for helping glucose move from the bloodstream into the body's cells, where it is used for energy.\n\nBy increasing insulin production, glibenclamide helps lower blood glucose levels, particularly after meals.\n\nRole of Metformin\n\nMetformin is part of the biguanide class of medications. It works differently from glibenclamide and supports blood sugar control in several ways:\n\nReduces glucose production in the liver\n\nImproves the body's sensitivity to insulin\n\nDecreases the absorption of sugar from food in the intestines\n\nBecause these two medications target different aspects of glucose regulation, their combined effect provides more effective control of blood sugar levels in people with Type 2 Diabetes.\n\nUses of GLIBEMIDE FORTE\n\nGLIBEMIDE FORTE is primarily used to treat and manage Type 2 Diabetes, especially in patients who require combination therapy to achieve better glycemic control.\n\n1. Management of Type 2 Diabetes\n\nThe main use of GLIBEMIDE FORTE is to help control blood glucose levels in adults diagnosed with Type 2 diabetes. It is typically prescribed when diet, exercise, and single-drug therapy are insufficient.\n\n2. Improving Insulin Utilization\n\nThe combination of glibenclamide and metformin enhances the body’s ability to use insulin efficiently. This helps ensure that glucose is effectively transported into cells rather than remaining in the bloodstream.\n\n3. Reducing High Blood Sugar Symptoms\n\nPatients with uncontrolled diabetes may experience symptoms such as excessive thirst, frequent urination, fatigue, and blurred vision. GLIBEMIDE FORTE helps manage these symptoms by stabilizing blood sugar levels.\n\n4. Preventing Diabetes-Related Complications\n\nConsistently elevated blood sugar can damage organs and tissues over time. Proper diabetes control with medications like GLIBEMIDE FORTE may reduce the risk of complications such as:\n\nNerve damage\n\nKidney disease\n\nEye problems\n\nCardiovascular disease\n\nKey Benefits of GLIBEMIDE FORTE\n\nGLIBEMIDE FORTE offers several advantages for patients managing diabetes.\n\n1. Dual Mechanism of Action\n\nOne of the primary benefits of GLIBEMIDE FORTE is its dual-action formula. While glibenclamide stimulates insulin release, metformin improves insulin sensitivity and reduces glucose production. This combined effect leads to more effective blood sugar control.\n\n2. Improved Glycemic Control\n\nRegular use of GLIBEMIDE FORTE helps maintain balanced blood sugar levels throughout the day. It can also contribute to lowering HbA1c levels, which indicate long-term glucose control.\n\n3. Convenient Combination Therapy\n\nInstead of taking two separate medications, GLIBEMIDE FORTE provides both active ingredients in a single tablet. This simplifies treatment and may improve medication adherence.\n\n4. Supports Energy Levels\n\nWhen blood sugar levels are stabilized, patients may experience improved energy levels and reduced fatigue associated with high glucose levels.\n\n5. Helps Reduce Risk of Long-Term Complications\n\nMaintaining healthy glucose levels is essential for preventing complications related to type 2 diabetes. Consistent treatment with GLIBEMIDE FORTE can support long-term health and well-being.\n\n6. Enhances Effectiveness of Lifestyle Changes\n\nGLIBEMIDE FORTE works best when combined with healthy habits such as balanced nutrition, regular exercise, and weight management.\n\nHow to Use GLIBEMIDE FORTE\n\nGLIBEMIDE FORTE should always be taken according to a doctor’s prescription.\n\nGeneral guidelines include:\n\nTake the medication with meals to reduce the risk of stomach discomfort.\n\nSwallow the tablet with water without crushing or chewing it unless advised otherwise.\n\nFollow the dosage schedule recommended by your healthcare provider.\n\nDo not skip doses or take more than prescribed.\n\nPatients should also regularly monitor their blood sugar levels and attend routine medical checkups while taking this medication.\n\nPossible Side Effects of GLIBEMIDE FORTE\n\nLike all medications, GLIBEMIDE FORTE may cause side effects in some individuals. Most side effects are mild and manageable, but patients should be aware of potential reactions.\n\nCommon Side Effects\n\nSome patients may experience:\n\nNausea\n\nMild stomach upset\n\nDiarrhea\n\nHeadache\n\nDizziness\n\nThese symptoms often improve as the body adjusts to the medication.\n\nHypoglycemia (Low Blood Sugar)\n\nBecause Glibenclamide increases insulin production, there is a possibility of hypoglycemia, especially if meals are skipped or excessive physical activity occurs. Symptoms may include:\n\nSweating\n\nShakiness\n\nRapid heartbeat\n\nHunger\n\nConfusion\n\nConsuming a quick source of sugar can help correct mild hypoglycemia.\n\nLess Common Side Effects\n\nSome individuals may experience:\n\nMetallic taste in the mouth\n\nLoss of appetite\n\nSkin rash\n\nRare but Serious Side Effects\n\nIn rare cases, severe reactions may occur, including:\n\nSevere hypoglycemia\n\nAllergic reactions\n\nLactic acidosis (a rare but serious condition associated with Metformin)\n\nPatients should seek immediate medical attention if they experience unusual weakness, breathing difficulty, or severe abdominal discomfort.\n\nPrecautions and Safety Information\n\nBefore starting GLIBEMIDE FORTE, patients should inform their healthcare provider about any existing health conditions, including:\n\nKidney disease\n\nLiver disorders\n\nHeart conditions\n\nHormonal disorders\n\nSevere infections\n\nCertain medications may interact with glibenclamide or metformin, so patients should inform their doctor about all medicines and supplements they are taking.\n\nPregnant or breastfeeding women should use GLIBEMIDE FORTE only under medical supervision.\n\nLifestyle Recommendations for Better Diabetes Control\n\nTo achieve the best results with GLIBEMIDE FORTE, patients should combine medication with healthy lifestyle habits, including:\n\nFollowing a balanced diabetic diet\n\nEngaging in regular physical activity\n\nMaintaining a healthy body weight\n\nMonitoring blood glucose levels regularly\n\nAttending routine health checkups\n\nThese lifestyle practices enhance the effectiveness of the medication and help maintain long-term health.\n\nConclusion\nGLIBEMIDE FORTE is a powerful combination medication containing Glibenclamide 5 mg and Metformin 500 mg, designed to help manage blood sugar levels in individuals with type 2 diabetes. By combining two complementary mechanisms of action, this medication helps improve insulin production, enhance insulin sensitivity, and reduce excess glucose production in the body.", "price": 44.0, "discountamount": 13.2, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "fat", "part", "Order", "EMAIL", "uptake", "nausea", "muscle", "adults", "release", "diarrhea", "vomiting", "patients", "glyburide", "effective", "management", "medications", "convenience", "supervision", "information", "side effects", "hypoglycemia", "tolerability", "sterispharma", "sterisonline", "Metformin HCI", "CALL/WHATSAPP", "Glibenclamide", "GLIBEMIDE FORTE", "adverse effects", "glycemic control", "insulin secretion", "treatment regimen", "convenient option", "insulin resistance", "blood sugar levels", "fixed-dose therapy", "sulfonylurea class", "allergic reactions", "dosage adjustments", "peripheral tissues", "regular monitoring", "insulin sensitivity", "individual response", "biguanide medication", "blood glucose levels", "intestinal absorption", "pancreatic beta cells", "two active ingredients", "combination medication", "hepatic glucose output", "healthcare professional", "lifestyle modifications", "type 2 diabetes mellitus", "hepatic glucose production", "postprandial glucose levels", "comprehensive treatment plan", "gastrointestinal disturbances", "multiple pathophysiological defects", "dual-action glucose-lowering therapy" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1282, "imageuri": "https://productimages.withfloats.com/actual/665eef804f159c14e15f27b7.png", "tileimageuri": "https://productimages.withfloats.com/tile/665eef804f159c14e15f27b7.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-04T10:42:06.137Z", "updatedon": "2026-03-05T07:49:03.558Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//glibenclamide-5mg-metformin-500mg/1282", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "GLIBEMIDE FORTE ", "category": "DIABETIC RANGE", "tags": [ "glibenclamide 5mg metformin 500mg tablet uses", "glibenclamide 5mg metformin 500mg dosage for diabetes", "glibenclamide 5mg metformin 500mg side effects", "glibenclamide metformin combination tablet benefits", "glibenclamide 5mg metformin 500mg tablet for type 2 diabetes", "glibenclamide 5mg metformin 500mg diabetes treatment", "glibenclamide 5mg metformin 500mg tablet review", "glibenclamide 5mg metformin 500mg blood sugar control", "buy glibenclamide 5mg metformin 500mg tablets online", "glibenclamide metformin 5mg 500mg tablet price", "best price glibenclamide metformin 5mg 500mg", "glibenclamide 5mg metformin 500mg uses dosage and side effects", "glibenclamide metformin tablet price and benefits" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "68e7a474f3481c1f16d3b038", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "sitagliptin 50mg glimepiride 2mg metformin 500mg", "description": "Sitagliptin 50mg, Metformin Hydrochloride 500mg & Glimepiride 2mg is a combination oral medication designed for the effective management of type 2 diabetes mellitus. This triple-action formula works synergistically to control blood glucose levels by addressing insulin resistance, enhancing insulin secretion, and regulating post-meal sugar spikes. Ideal for patients who require more than one mechanism to maintain stable blood sugar, this combination is often prescribed when monotherapy or dual therapy is insufficient.\n\nUses\n\nManagement of Type 2 Diabetes Mellitus in adults.\n\nHelps in controlling fasting and postprandial blood glucose levels.\n\nRecommended for patients whose blood sugar is not adequately controlled with a single antidiabetic medicine.\n\nCan be used as part of a comprehensive diabetes management plan, including diet and exercise.\n\nKey Benefits\n\nDual Mechanism Control:\n\nMetformin Hydrochloride reduces hepatic glucose production and improves insulin sensitivity.\n\nGlimepiride stimulates pancreatic beta cells to secrete more insulin.\n\nSitagliptin enhances incretin hormones, leading to better regulation of post-meal glucose levels.\n\nEffective Blood Sugar Management:\nHelps maintain optimal fasting and postprandial glucose levels, reducing the risk of diabetes-related complications.\n\nConvenient Combination Therapy:\nCombines three mechanisms in a single tablet, reducing the pill burden and improving patient compliance.\n\nSupports Overall Health:\nHelps prevent long-term complications such as neuropathy, nephropathy, retinopathy, and cardiovascular risks associated with diabetes.\n\nPossible Side Effects\n\nWhile generally well-tolerated, some patients may experience:\n\nGastrointestinal issues: nausea, vomiting, diarrhea, or abdominal discomfort (mainly from Metformin).\n\nHypoglycemia (low blood sugar): more likely due to Glimepiride; symptoms include dizziness, sweating, or shakiness.\n\nAllergic reactions: rash, itching, or swelling in rare cases.\n\nOther mild effects: headache, fatigue, or minor changes in taste.\n\nNote: Patients should always consult their doctor before starting this combination and report any unusual symptoms immediately.\n\nConclusion\n\nThe Sitagliptin, Metformin Hydrochloride & Glimepiride combination provides a powerful, multi-targeted approach to managing type 2 diabetes. By tackling high blood sugar from different angles, it supports better glucose control, enhances overall quality of life, and reduces the risk of diabetes-related complications. When used alongside proper diet, exercise, and medical guidance, this combination can be a cornerstone in effective diabetes management.", "price": 180.0, "discountamount": 54.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2185, "imageuri": "https://productimages.withfloats.com/actual/68e7a47b040520d37b5e6b34.png", "tileimageuri": "https://productimages.withfloats.com/tile/68e7a47b040520d37b5e6b34.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-10-09T12:03:00.012Z", "updatedon": "2026-03-13T10:48:17.253Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//sitagliptin-50mg-glimepiride-2mg-metformin-500mg/2185", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "ST GLIPTIN GM", "category": "DIABETIC RANGE", "tags": [ "Sitagliptin", "Metformin Hydrochloride", "Glimepiride", "type 2 diabetes mellitus", "sitagliptin 50 mg glimepiride 2 mg metformin 500 mg tablet uses", "sitagliptin glimepiride metformin combination benefits for diabetes", "sitagliptin glimepiride metformin tablet dosage guide", "sitagliptin glimepiride metformin tablets how it works for blood sugar", "sitagliptin glimepiride metformin tablets doctor prescription guide", "buy sitagliptin glimepiride metformin tablets online", "sitagliptin glimepiride metformin tablet price in india", "sitagliptin glimepiride metformin tablets supplier", "sitagliptin glimepiride metformin tablets supplier", "who should take sitagliptin glimepiride metformin tablets", "sitagliptin glimepiride metformin tablets weight loss effect", "sitagliptin glimepiride metformin tablets kidney safety" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6661afd366170d1ff8cb4626", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Gliclazide 60mg SR Pioglitazone 15mg Metformin HCL 500mgSR", "description": "TRIGLICLAGLAZE 60 \nGliclazide 60mg (SR), pioglitazone 15 mg, and metformin HCl 500 mg (SR)\nTRIGLICLAGLAZE 60 is a combination medication designed to effectively manage type 2 diabetes mellitus by addressing multiple aspects of glucose regulation. It combines three key components: Gliclazide 60mg (SR), Pioglitazone 15mg, and Metformin HCI 500mg (SR), each contributing to improved blood sugar control through distinct mechanisms of action.\n\nGliclazide 60mg (SR): Gliclazide is a sulfonylurea medication that stimulates the pancreas to release insulin. This insulin release helps lower blood sugar levels, especially after meals, by facilitating glucose uptake into cells.\n\nPioglitazone 15 mg: Pioglitazone belongs to the thiazolidinedione class and works by improving insulin sensitivity in peripheral tissues such as muscle and fat cells. Enhanced insulin sensitivity allows for better utilization of glucose, reducing insulin resistance and promoting more efficient blood sugar management.\n\nMetformin HCI 500mg (SR): Metformin is a biguanide medication that primarily works by reducing glucose production in the liver and increasing insulin sensitivity in muscle cells. It also improves glucose uptake by cells and reduces the absorption of glucose from the digestive tract.\n\nKey Benefits of TRIGLICLAGLAZE 60:\nComprehensive Glucose Control: By combining Gliclazide (SR), Pioglitazone, and Metformin HCI (SR), TRIGLICLAGLAZE 60 offers comprehensive control over blood sugar levels throughout the day.\n\nStimulates Insulin Release: Gliclazide's action in stimulating insulin release from the pancreas helps manage postprandial (after-meal) glucose spikes, contributing to overall glucose control.\n\nImproves Insulin Sensitivity: Pioglitazone enhances insulin sensitivity in tissues, leading to better glucose uptake and utilization by cells. This helps reduce insulin resistance, a common feature of type 2 diabetes.\n\nReduces Glucose Production: Metformin HCI lowers glucose production in the liver and improves insulin action in muscle cells, leading to lower fasting blood sugar levels and enhanced glucose utilization.\n\nExtended Release Formulation: The sustained-release formulations of Gliclazide and Metformin ensure a gradual and prolonged release of the medications, providing consistent blood sugar control and minimizing the risk of hypoglycemia or hyperglycemia.\n\nDosage and Administration:\nTRIGLICLAGLAZE 60 is typically taken orally once or twice daily, with meals to reduce gastrointestinal side effects.\nDosage adjustments may be required based on blood sugar levels and individual response to treatment. Follow your healthcare provider's instructions.\nFor further information:\nEMAIL: info@sterispharma.com / contact@sterispharma.com \n Order Now", "price": 155.0, "discountamount": 47.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "SR", "day", "risk", "meals", "Order", "liver", "EMAIL", "gradual", "fasting", "pancreas", "Enhanced", "treatment", "fat cells", "absorption", "information", "medications", "muscle cells", "Pioglitazone", "sterisonline", "Key Benefits", "hypoglycemia", "instructions", "sterispharma", "postprandial", "hyperglycemia", "CALL/WHATSAPP", "Metformin HCL", "Metformin HCI", "Administration", "glucose uptake", "TRIGLICLAGLAZE", "common feature", "glucose spikes", "insulin action", "insulin release", "Gliclazide 60mg", "digestive tract", "multiple aspects", "prolonged release", "Dosage adjustments", "peripheral tissues", "blood sugar levels", "glucose production", "insulin resistance", "glucose regulation", "distinct mechanisms", "healthcare provider", "individual response", "glucose utilization", "insulin sensitivity", "three key components", "biguanide medication", "comprehensive control", "combination medication", "sulfonylurea medication", "thiazolidinedione class", "overall glucose control", "type 2 diabetes mellitus", "Extended Release Formulation", "Comprehensive Glucose Control", "gastrointestinal side effects", "sustained-release formulations", "consistent blood sugar control", "efficient blood sugar management" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1485, "imageuri": "https://productimages.withfloats.com/actual/6661afd7f21358d53af3cd71.png", "tileimageuri": "https://productimages.withfloats.com/tile/6661afd7f21358d53af3cd71.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-06T12:47:15.16Z", "updatedon": "2026-03-13T07:32:49.604Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//gliclazide-60mg-sr-pioglitazone-15mg-metformin-hcl-500mgsr/1485", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "TRIGLICLAGLAZE 60 ", "category": "DIABETIC RANGE", "tags": [ "TRIGLICLAGLAZE 60", "Gliclazide 60mg (SR)", "Pioglitazone 15mg", "Metformin HCL 500mg(SR)", "Metformin SR 500mg uses", "Metformin SR 500 price", "Metformin SR 500 side effects" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6661aea4d91d281c30c76019", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Glibenclamide 5mg Metformin HCI 500mg Pioglitazone 15mg", "description": "Glibenclamide 5mg Metformin HCI 500mg Pioglitazone 15mg\n\nManaging type 2 diabetes effectively often requires a combination approach that targets multiple pathways of blood sugar control. The combination of Glibenclamide 5mg, Metformin HCI 500mg, and Pioglitazone 15mg is a powerful triple therapy designed to help patients achieve better glycemic control when single or dual therapy is not enough. This formulation is widely prescribed by healthcare professionals for its synergistic action and long-term benefits in diabetes management.\n\nIf you are exploring this medicine as a treatment option, this detailed guide will help you understand how it works, its benefits, dosage, precautions, and why it is considered an effective choice for people with type 2 diabetes.\n\nWhat is Glibenclamide 5mg Metformin HCI 500mg Pioglitazone 15mg?\n\nThis combination medicine contains three anti-diabetic agents:\n\nGlibenclamide (5mg): A sulfonylurea that stimulates insulin secretion from the pancreas.\nMetformin HCI (500mg): A biguanide that reduces glucose production in the liver and improves insulin sensitivity.\nPioglitazone (15mg): A thiazolidinedione that enhances insulin sensitivity in muscle and fat tissues.\n\nTogether, these components address different aspects of diabetes, making it easier to control blood sugar levels effectively.\n\nHow Does This Combination Work?\n\nThe strength of this formulation lies in its triple mechanism of action:\n\n1. Increased Insulin Secretion\n\nGlibenclamide stimulates the pancreas to release more insulin, especially after meals.\n\n2. Reduced Glucose Production\n\nMetformin decreases glucose production in the liver and improves the body’s response to insulin.\n\n3. Improved Insulin Sensitivity\n\nPioglitazone helps body cells utilize insulin more efficiently, reducing insulin resistance.\n\nCombined Effect\n\nBy working on multiple pathways, this medicine:\n\nLowers fasting and post-meal blood sugar\nImproves HbA1c levels\nReduces the risk of long-term complications\nBuyer Intent: Why Choose This Triple Combination?\n\nIf you are considering this medicine, here’s why it stands out:\n\n1. Comprehensive Blood Sugar Control\n\nUnlike single-drug therapy, this combination tackles diabetes from three angles, offering better control.\n\n2. Suitable for Uncontrolled Diabetes\n\nIdeal for patients whose blood sugar remains high despite using one or two medications.\n\n3. Convenience of Single Tablet\n\nInstead of taking multiple pills, you get all three medicines in one tablet, improving compliance.\n\n4. Cost-Effective Treatment\n\nCombining three medicines into one reduces overall treatment costs.\n\n5. Doctor-Recommended Therapy\n\nWidely prescribed due to its proven effectiveness in clinical practice.\n\nKey Benefits of Glibenclamide + Metformin + Pioglitazone\nHelps maintain stable blood glucose levels\nReduces insulin resistance\nImproves pancreatic function\nLowers risk of diabetes complications like neuropathy and kidney damage\nEnhances overall metabolic health\nSupports long-term diabetes management\nWho Should Use This Medicine?\n\nThis combination is typically prescribed for:\n\nAdults with type 2 diabetes mellitus\nPatients not responding well to dual therapy\nIndividuals with insulin resistance\nPatients needing aggressive glycemic control\n\nNote: It is not suitable for type 1 diabetes or diabetic ketoacidosis.\n\nDosage Guidelines\nRecommended Usage:\nUsually taken once or twice daily with meals\nDosage depends on individual blood sugar levels and doctor’s advice\nImportant Tips:\nTake with food to avoid stomach upset\nDo not skip doses\nFollow a consistent schedule\nNever self-adjust the dose\nMissed Dose:\nTake as soon as remembered\nSkip if it’s close to the next dose\nPossible Side Effects\n\nLike any medication, this combination may cause side effects.\n\nCommon Side Effects:\nNausea\nDiarrhea\nStomach discomfort\nWeight gain\nHypoglycemia (low blood sugar)\nLess Common Side Effects:\nHeadache\nDizziness\nEdema (swelling)\nSerious Side Effects (Rare but Important)\nSevere hypoglycemia\nLactic acidosis (rare but serious, linked to metformin)\nLiver problems\nHeart-related issues (in rare cases with pioglitazone)\n\nSeek immediate medical attention if symptoms like extreme weakness, breathing difficulty, or severe abdominal pain occur.\n\nPrecautions & Warnings\n\nBefore starting this medicine, consider the following:\n\n1. Kidney Function\n\nMetformin is processed through the kidneys, so kidney health must be monitored.\n\n2. Liver Conditions\n\nPatients with liver disease should use this medicine cautiously.\n\n3. Heart Health\n\nPioglitazone may cause fluid retention; consult your doctor if you have heart issues.\n\n4. Alcohol Consumption\n\nAvoid excessive alcohol to reduce the risk of lactic acidosis.\n\n5. Pregnancy & Breastfeeding\n\nUse only if prescribed by a doctor.\n\nLifestyle Tips for Better Results\n\nTo maximize the effectiveness of this medicine:\n\nFollow a balanced diabetic diet\nExercise regularly (30 minutes daily)\nMonitor blood sugar levels frequently\nMaintain a healthy weight\nAvoid smoking and alcohol\nFrequently Asked Questions (FAQs)\nQ1: What is this medicine used for?\n\nIt is used to control blood sugar levels in type 2 diabetes.\n\nQ2: Can I take it on an empty stomach?\n\nIt is recommended to take it with food to reduce side effects.\n\nQ3: Does it cause low blood sugar?\n\nYes, due to glibenclamide, hypoglycemia may occur if meals are skipped.\n\nQ4: How long should I take it?\n\nIt is usually a long-term treatment as prescribed by your doctor.\n\nQ5: Can it be used with insulin?\n\nIn some cases, yes—but only under medical supervision.\n\nBuying Guide: What to Consider Before Purchase\n\nWhen purchasing this medicine, ensure:\n\nIt is prescribed by a qualified doctor\nYou buy from a trusted pharmacy\nCheck expiry date and packaging\nFollow proper storage conditions (cool, dry place)\nConclusion\n\nThe combination of glibenclamide 5 mg, metformin HCl 500 mg, and pioglitazone 15 mg is a highly effective and reliable option for managing type 2 diabetes, especially in patients who need stronger glycemic control. Its triple-action formula addresses insulin secretion, insulin resistance, and glucose production, making it a comprehensive solution for long-term diabetes care.", "price": 74.0, "discountamount": 22.2, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "body", "risk", "Order", "500mg", "EMAIL", "liver", "meals", "cells", "muscle", "doctor", "adipose", "response", "pancreas", "condition", "management", "one tablet", "utilization", "information", "medications", "Pioglitazone", "sterispharma", "Key Benefits", "fat) tissues", "instructions", "postprandial", "inflammation", "sterisonline", "CALL/WHATSAPP", "Metformin HCI", "Glibenclamide", "Administration", "typical dosage", "glucose uptake", "lipid profiles", "Insulin Release", "TRI GLIBEN FORTE", "insulin secretion", "multiple pathways", "dosage adjustments", "glucose metabolism", "peripheral tissues", "sulfonylurea class", "insulin resistance", "blood sugar control", "healthcare provider", "insulin sensitivity", "additional benefits", "biguanide medication", "first-line treatment", "meal) glucose spikes", "cardiovascular health", "comprehensive control", "combination medication", "high blood sugar levels", "overall glycemic control", "Cardiometabolic Benefits", "type 2 diabetes mellitus", "Hepatic Glucose Production", "thiazolidinedione medication", "intestinal glucose absorption", "Comprehensive Glucose Control", "gastrointestinal side effects", "inadequate insulin production" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1483, "imageuri": "https://productimages.withfloats.com/actual/69e718d33e42a8b926525922.png", "tileimageuri": "https://productimages.withfloats.com/tile/69e718d33e42a8b926525922.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-06T12:42:12.134Z", "updatedon": "2026-06-09T12:09:22.817Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//glibenclamide-5mg-metformin-hci-500mg-pioglitazone-15mg/1483", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "TRI GLIBEN FORTE ", "category": "DIABETIC RANGE", "tags": [ "glibenclamide 5mg", "glibenclamide 5mg + metformin 500mg", "glibenclamide 5mg metformin 500mg", "glibenclamide 5mg metformin 500mg dosage", "glibenclamide 5mg uses", "glibenclamide 5mg + metformin 500mg dosage", "glibenclamide 5mg tab", "glibenclamide 5mg tablet", "glimepiride 5mg metformin 500mg pioglitazone 15mg", "pioglitazone 15mg", "pioglitazone 15mg tablets price", "pioglitazone 15mg uses", "pioglitazone 15mg price", "pioglitazone 15mg + metformin 500mg", "pioglitazone 15mg tab" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6661adf866170d1ff8cb45d2", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Teneligliptin 20mg, Pioglitazone 15mg & Extended Release Metformin Hydrochloride 500mg", "description": "TENELIGOLD PM 500 \nTeneligliptin 20mg, Pioglitazone 15mg & Extended Release Metformin Hydrochloride 500mg\n\nManaging type 2 diabetes requires the right combination of lifestyle habits, regular monitoring, and effective medication support. Teneligliptin 20 mg, pioglitazone 15 mg & extended-release metformin hydrochloride 500 mg is a powerful triple-combination medicine designed to help control blood sugar levels in adults with type 2 diabetes mellitus. This combination is often prescribed when a single medicine alone is not enough to achieve desired glucose control.\n\nIf you are searching for a trusted treatment option that works through multiple mechanisms, this medicine can be a practical choice under your doctor’s guidance. It helps improve insulin sensitivity, reduce excess glucose production, and support better post-meal sugar management.\n\nWhat is Teneligliptin 20mg, Pioglitazone 15mg & Extended Release Metformin Hydrochloride 500mg?\n\nThis medication combines three clinically proven anti-diabetic agents in one tablet:\n\nTeneligliptin 20mg – A DPP-4 inhibitor that helps increase insulin release after meals.\nPioglitazone 15mg – Improves the body’s sensitivity to insulin.\nExtended Release Metformin Hydrochloride 500mg – Reduces glucose production in the liver and improves insulin function with slow-release action.\n\nThis combination helps maintain stable blood sugar throughout the day while reducing sudden spikes after meals.\n\nHow Does It Work?\n1. Teneligliptin 20mg\n\nTeneligliptin works by blocking the DPP-4 enzyme. This increases incretin hormone levels, which stimulate insulin secretion when blood sugar rises and lower glucagon production.\n\n2. Pioglitazone 15mg\n\nPioglitazone helps cells become more responsive to insulin. This allows glucose to enter cells more efficiently and reduces insulin resistance.\n\n3. Extended-Release Metformin Hydrochloride 500mg\n\nMetformin ER decreases sugar production in the liver and slows intestinal absorption of glucose. The extended-release form provides smoother action and may reduce stomach discomfort.\n\nWhy Doctors Recommend This Combination\n\nFor many patients with type 2 diabetes, one medicine may not be enough over time. This triple-combination tablet is commonly recommended when:\n\nBlood sugar remains uncontrolled with metformin alone\nHbA1c levels stay above target\nInsulin resistance is significant\nPost-meal sugar spikes are frequent\nA simplified once-daily combination is preferred\nKey Benefits of Teneligliptin 20 mg Pioglitazone, 15mg & Extended Release Metformin Hydrochloride 500mg\nBetter Blood Sugar Control\n\nTargets fasting sugar, post-meal sugar, and long-term HbA1c levels.\n\nTriple Action Formula\n\nThree medicines in one tablet offer a broader treatment approach.\n\nImproves Insulin Sensitivity\n\nPioglitazone supports better glucose utilization in the body.\n\nConvenient Dosing\n\nOne combination tablet may reduce pill burden.\n\nExtended Release Comfort\n\nMetformin ER may be gentler on the stomach than regular metformin in some patients.\n\nSupports Long-Term Diabetes Management\n\nUseful for patients needing stronger sugar control under physician supervision.\n\nWho Can Benefit from This Medicine?\n\nThis medicine may be suitable for adults diagnosed with type 2 diabetes mellitus who need combination therapy. It is commonly used in patients who:\n\nHave uncontrolled diabetes despite diet and exercise\nNeed additional support beyond metformin\nWant easier medication compliance\nHave insulin resistance issues\n\nIt is not meant for type 1 diabetes or diabetic ketoacidosis.\n\nHow to Take It\n\nAlways use this medicine exactly as prescribed by your healthcare provider.\n\nGeneral usage tips:\n\nUsually taken once daily or as directed\nTake with meals to reduce stomach discomfort\nSwallow whole; do not crush or break ER tablets\nMaintain regular meal timing\nContinue exercise and diabetic diet plan\n\nNever change dosage without medical advice.\n\nCommon Side Effects\n\nLike all medicines, some side effects may occur. Most are mild and manageable.\n\nFrequently Reported Side Effects\nNausea\nStomach upset\nDiarrhea\nHeadache\nWeight gain\nMild swelling in legs or ankles\nLow appetite\nDizziness\n\nIf symptoms persist, consult your doctor.\n\nSerious Side Effects (Need Immediate Medical Help)\n\nSeek medical attention if you notice:\n\nSevere weakness\nDifficulty breathing\nUnusual swelling\nChest pain\nSevere abdominal pain\nPersistent vomiting\nSigns of low blood sugar\nYellowing of eyes or skin\nPrecautions Before Use\n\nBefore taking Teneligliptin 20mg, Pioglitazone 15mg & Extended Release Metformin Hydrochloride 500mg, inform your doctor if you have:\n\nKidney disease\nLiver disorder\nHeart failure\nBladder problems\nHistory of pancreatitis\nAlcohol dependency\nPregnancy or breastfeeding concerns\n\nRegular blood tests may be required during treatment.\n\nCan It Cause Low Blood Sugar?\n\nThis medicine alone has a lower risk of hypoglycemia compared with some diabetes drugs. However, low sugar can happen if combined with:\n\nInsulin\nSulfonylureas\nSkipped meals\nExcess exercise\nAlcohol intake\nSigns of Low Sugar\nSweating\nTrembling\nHunger\nConfusion\nFast heartbeat\n\nKeep glucose tablets or a sugary snack handy if advised.\n\nLifestyle Tips for Best Results\n\nMedicine works best when combined with healthy habits.\n\nFollow a Diabetic Diet\n\nChoose:\n\nWhole grains\nFiber-rich vegetables\nLean protein\nControlled carbohydrate portions\nExercise Regularly\n\nAt least 30 minutes daily walking or approved exercise.\n\nMonitor Blood Sugar\n\nCheck glucose levels regularly and maintain records.\n\nStay Hydrated\n\nDrink enough water unless restricted by your doctor.\n\nAvoid Smoking & Alcohol Excess\n\nThese can worsen diabetic complications.\n\nWhy Buyers Prefer Combination Tablets\n\nMany patients prefer combination diabetes tablets because:\n\nFewer tablets daily\nBetter adherence to treatment\nCost-effective compared to separate medicines\nEasier routine management\nMulti-target glucose control\nStorage Instructions\nStore in a cool, dry place\nKeep away from moisture\nProtect from direct sunlight\nKeep out of reach of children\nFrequently Asked Questions\nIs this medicine good for newly diagnosed diabetes?\n\nUsually prescribed when lifestyle changes or single-drug therapy is insufficient. Doctor decides based on sugar levels.\n\nCan I take it for a long time?\n\nYes, diabetes often requires long-term treatment, but only under regular medical supervision.\n\nDoes it help reduce HbA1c?\n\nYes, this combination is commonly used to lower HbA1c and improve overall glycemic control.\n\nCan I stop once sugar becomes normal?\n\nNo. Do not stop medicine without consulting your doctor.\n\nIs it safe for elderly patients?\n\nIt may be used depending on kidney, liver, and heart health. Dose adjustment may be needed.\n\nFinal Words\n\nIf you are looking for an effective and convenient treatment option for type 2 diabetes, Teneligliptin 20mg, Pioglitazone 15mg & Extended Release Metformin Hydrochloride 500mg can be a valuable solution. With triple-action support, improved insulin response, and extended-release comfort, it helps many patients achieve better glucose control.\n", "price": 180.0, "discountamount": 54.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "GIP", "meals", "500mg", "EMAIL", "cells", "drugs", "GLP-1", "liver", "glass", "water", "dosing", "muscle", "action", "doctor", "fasting", "response", "treatment", "management", "one tablet", "utilization", "information", "postprandial", "Pioglitazone", "Key Benefits", "fat) tissues", "sterisonline", "sterispharma", "instructions", "DPP-4 enzyme", "CALL/WHATSAPP", "TENELIGOLD PM", "Teneligliptin", "glucose uptake", "Administration", "typical dosage", "glucose control", "glucagon levels", "glucagon release", "incretin hormones", "insulin secretion", "sustained release", "medical condition", "dosage adjustments", "metabolic disorder", "glucose regulation", "peripheral tissues", "insulin resistance", "glucose production", "healthcare provider", "insulin sensitivity", "biguanide medication", "Reduced Side Effects", "comprehensive control", "combination medication", "DPP-4) inhibitor class", "dipeptidyl peptidase-4", "high blood sugar levels", "overall glycemic control", "type 2 diabetes mellitus", "meal) blood sugar levels", "Incretin Hormone Enhancement", "thiazolidinedione medication", "Extended-release formulations", "inadequate insulin production", "intestinal glucose absorption", "gastrointestinal side effects", "Comprehensive Glycemic Control", "immediate-release formulations", "Extended-Release Metformin Hydrochloride", "glucose-dependent insulinotropic peptide", "Extended Release Metformin Hydrochloride" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1481, "imageuri": "https://productimages.withfloats.com/actual/6661adfd637f8700d7ca4512.png", "tileimageuri": "https://productimages.withfloats.com/tile/6661adfd637f8700d7ca4512.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-06T12:39:20.713Z", "updatedon": "2026-04-24T07:45:48.471Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//teneligliptin-20mg-pioglitazone-15mg-extended-release-metformin-hydrochloride-500mg/1481", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "TENELIGOLD PM 500 ", "category": "DIABETIC RANGE", "tags": [ "Teneligliptin 20mg", "Pioglitazone 15mg", "Metformin Hydrochloride 500mg", "Teneligliptin Tablets 20 mg uses", "Teneligliptin 20 mg + Metformin 500", "Teneligliptin 20 mg side effects", "teneligliptin pioglitazone", "teneligliptin pioglitazone metformin", "teneligliptin pioglitazone 20 30", "teneligliptin pioglitazone combination", "teneligliptin pioglitazone brand name", "Teneligliptin 20mg Pioglitazone 15mg Metformin 500mg tablet", "Teneligliptin Pioglitazone Metformin ER tablet uses", "Buy Teneligliptin 20mg Pioglitazone 15mg Metformin 500mg", "Bulk order Teneligliptin Pioglitazone Metformin tablets" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6661ac5887f0960e14a2c914", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "teneligliptin 20mg + metformin 500mg", "description": "TENELIGOLD M 500 \nmetformin teneligliptin\nMetformin Teneligliptin\n\nManaging type 2 diabetes effectively often requires a treatment plan that controls blood sugar from multiple angles. Metformin Teneligliptin is a widely prescribed combination medicine designed to help adults with type 2 diabetes maintain healthier glucose levels. This dual-combination therapy supports better insulin action, lowers excess sugar production, and helps reduce post-meal sugar spikes.\n\nIf you are searching for a reliable diabetes treatment that combines proven ingredients in one tablet, Metformin Teneligliptin can be an excellent option under medical guidance. It is commonly recommended when diet, exercise, and single-drug treatment no longer provide enough sugar control.\n\nWhat is Metformin-Teneligliptin?\n\nMetformin-teneligliptin is a combination of two antidiabetic medicines:\n\nMetformin – One of the most trusted first-line treatments for type 2 diabetes that reduces glucose production in the liver and improves insulin sensitivity.\nTeneligliptin – A DPP-4 inhibitor that helps the body release insulin when blood sugar rises and lowers glucagon secretion.\n\nTogether, they provide balanced blood sugar management throughout the day.\n\nHow Do Metformin and Teneligliptin Work?\n\nThis medicine works through two complementary mechanisms:\n\nMetformin Action\n\nMetformin helps control blood sugar by:\n\nReducing glucose production in the liver\nImproving insulin sensitivity\nLowering sugar absorption from the intestine\nSupporting stable fasting sugar levels\nTeneligliptin Action\n\nTeneligliptin works by blocking the DPP-4 enzyme, which increases incretin hormones. These hormones help:\n\nIncrease insulin release after meals\nReduce glucagon levels\nLower post-meal sugar spikes\nImprove overall glycemic control\n\nThe combination provides stronger results than either medicine alone in many patients.\n\nKey Benefits of Metformin Teneligliptin\nBetter Blood Sugar Control\n\nHelps manage fasting blood sugar, post-meal glucose, and HbA1c levels.\n\nDual-Action Formula\n\nWorks on both insulin release and insulin resistance.\n\nSupports Long-Term Diabetes Management\n\nUseful for patients needing stronger glucose control over time.\n\nConvenient Combination Tablet\n\nTwo effective medicines in one tablet can improve treatment adherence.\n\nLower Risk of Weight Gain\n\nCompared with some other diabetes medicines, this combination is often weight-neutral or weight-friendly depending on lifestyle factors.\n\nWhy Buyers Search for Metformin Teneligliptin\n\nMany patients and healthcare providers choose this combination because it offers dependable diabetes management with convenience. It is often selected when:\n\nMetformin alone is not enough\nHbA1c remains above target\nPost-meal sugar spikes are frequent\nA combination tablet is preferred\nConsistent glucose control is needed\nWho Should Use Metformin/Teneligliptin?\n\nThis medicine is generally prescribed for adults with type 2 diabetes mellitus. It may be suitable for patients who:\n\nNeed better sugar control\nHave uncontrolled diabetes despite lifestyle changes\nNeed combination therapy\nPrefer fewer tablets daily\n\nIt is not intended for type 1 diabetes or diabetic ketoacidosis.\n\nDosage and How to Take\n\nAlways take Metformin Teneligliptin exactly as prescribed by your doctor.\n\nGeneral Usage Tips\nUsually taken once or twice daily depending on strength and brand\nBest taken with food to reduce stomach discomfort\nSwallow tablet whole with water\nTake at the same time daily\nDo not skip doses regularly\n\nNever increase or decrease the dose without medical advice.\n\nCommon Side Effects of Metformin Teneligliptin\n\nMost side effects are mild and temporary, especially during the first few weeks.\n\nCommonly Reported Side Effects\nNausea\nLoose stools\nStomach discomfort\nHeadache\nDizziness\nMild weakness\nGas or bloating\nCold-like symptoms\n\nIf these continue, consult your healthcare provider.\n\nSerious Side Effects (Seek Immediate Help)\n\nGet urgent medical care if you experience:\n\nSevere abdominal pain\nDifficulty breathing\nPersistent vomiting\nSevere weakness\nAllergic rash or swelling\nChest pain\nYellowing of eyes or skin\nImportant Precautions\n\nBefore taking this medicine, tell your doctor if you have:\n\nKidney disease\nLiver problems\nHeart disease\nPancreatitis history\nAlcohol dependence\nDehydration issues\nPregnancy or breastfeeding concerns\n\nRegular blood sugar and kidney function tests may be advised.\n\nCan Metformin and Teneligliptin Cause Low Blood Sugar?\n\nWhen used alone, the risk of hypoglycemia is relatively low. However, low sugar may happen if combined with:\n\nInsulin\nSulfonylureas\nSkipped meals\nHeavy exercise\nExcess alcohol use\nSigns of Low Blood Sugar\nSweating\nHunger\nShaking\nFast heartbeat\nConfusion\nIrritability\n\nCarry a quick sugar source if recommended by your doctor.\n\nLifestyle Tips for Best Results\n\nMedicine gives better results when combined with healthy habits.\n\nEat a Balanced Diabetic Diet\n\nChoose:\n\nWhole grains\nFresh vegetables\nLean proteins\nFiber-rich foods\nControlled carbohydrate portions\nStay Active\n\nWalk, cycle, swim, or exercise for at least 30 minutes most days.\n\nMonitor Sugar Levels\n\nRegular testing helps track treatment success.\n\nMaintain Healthy Weight\n\nWeight management improves insulin function.\n\nAvoid Smoking and Limit Alcohol\n\nThese can worsen diabetes-related risks.\n\nWhy Combination Tablets Are Popular\n\nPatients often prefer combination medicines because they offer:\n\nFewer tablets daily\nEasier medication routine\nBetter treatment compliance\nCost-effective management\nMultiple benefits in one dose\nStorage Instructions\nStore in a cool, dry place\nKeep away from sunlight\nProtect from moisture\nKeep out of reach of children\nFrequently Asked Questions\nIs Metformin Teneligliptin effective for diabetes?\n\nYes, it is commonly used for type 2 diabetes and can help improve glucose control.\n\nCan I take it long-term?\n\nYes, many patients use it long-term under doctor supervision.\n\nDoes it reduce HbA1c?\n\nYes, this combination is often prescribed to help lower HbA1c.\n\nCan I stop medicine when sugar becomes normal?\n\nNo. Always consult your doctor before stopping or changing treatment.\n\nIs it safe for older adults?\n\nIt may be used depending on kidney and overall health. Your doctor will guide dosing.\n\nWhy Choose a Trusted Brand?\n\nWhen buying Metformin Teneligliptin, quality matters. Choose a trusted pharmaceutical manufacturer with strong quality standards, reliable packaging, and consistent formulation. This helps ensure better treatment confidence and product safety.", "price": 122.75, "discountamount": 36.83, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "day", "Order", "meals", "glass", "risks", "water", "EMAIL", "action", "option", "amount", "kidney", "doctor", "fasting", "reduced", "tissues", "Nursing", "Low Risk", "Benefits", "Pregnancy", "absorption", "overweight", "one tablet", "medications", "supplements", "utilization", "information", "TENELIGOLD M", "Hypoglycemia", "muscle cells", "sterispharma", "postprandial", "sterisonline", "many patients", "breastfeeding", "CALL/WHATSAPP", "typical dosage", "Administration", "liver problems", "glucose uptake", "low blood sugar", "Medical History", "glucagon levels", "biguanide class", "DPP-4) inhibitor", "Weight Management", "weight neutrality", "obese individuals", "insulin secretion", "glucose regulation", "modest weight loss", "Metformin SR 500mg", "glucose metabolism", "insulin resistance", "glucagon secretion", "different pathways", "Teneligliptin 20mg", "Dosage adjustments", "medical conditions", "insulin sensitivity", "healthcare provider", "individual response", "blood glucose levels", "Safety Considerations", "pancreatic beta cells", "combination medication", "dipeptidyl peptidase-4", "high blood sugar levels", "overall glycemic control", "Enhanced Incretin Effect", "meal) blood sugar levels", "type 2 diabetes mellitus", "oral antidiabetic medication", "gastrointestinal side effects", "inadequate insulin production", "Comprehensive Glycemic Control", "Metformin Hydrochloride Sustained Release" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1479, "imageuri": "https://productimages.withfloats.com/actual/6661ac5c4b296a211c2d34ee.jpg", "tileimageuri": "https://productimages.withfloats.com/tile/6661ac5c4b296a211c2d34ee.jpg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-06T12:32:24.912Z", "updatedon": "2026-04-24T08:40:32.665Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//teneligliptin-20mg-metformin-500mg/1479", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "TENELIGOLD M 500 ", "category": "DIABETIC RANGE", "tags": [ "metformin teneligliptin", "metformin teneligliptin combination", "metformin teneligliptin uses", "tab metformin 500mg", "tab metformin 500mg uses in hindi", "tab metformin 500mg uses", "metformin 500mg", "teneligliptin 20mg", "teneligliptin 20mg metformin 500 mg brands", "teneligliptin 20mg + metformin 500mg", "teneligliptin 20mg uses", "tablet teneligliptin 20mg", "teneligliptin 20mg metformin 500", "tab teneligliptin 20mg price" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6661a57d8da3a81d5c6a17dd", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Mycophenolate mofetil 500mg", "description": "MYCOPLASM M 500\nMycophenolate mofetil (500mg)\nMycoplasm M 500 is a medication containing Mycophenolate Mofetil in a 500mg dose. Mycophenolate Mofetil is an immunosuppressive drug used to prevent rejection in organ transplantation, particularly kidney, heart, and liver transplants. It works by inhibiting the proliferation of T and B lymphocytes, which are involved in the immune response that leads to rejection.\n\nThis medication is typically prescribed in combination with other immunosuppressants as part of a comprehensive transplant treatment regimen. It is important to take Mycoplasm M 500 exactly as prescribed by your healthcare provider to ensure optimal therapeutic outcomes and to minimize the risk of rejection or other complications.\n\nCommon side effects of Mycophenolate Mofetil may include gastrointestinal disturbances such as nausea, vomiting, diarrhea, and abdominal pain. It can also increase the risk of infections due to its immunosuppressive effects. Patients should be monitored regularly by their healthcare provider while taking this medication to assess for any potential adverse effects and to adjust the dosage as needed.\n\nMycoplasm M 500 should not be used in pregnant women or those planning to become pregnant without consulting a healthcare professional, as it can cause harm to the developing fetus. Additionally, it may interact with other medications, so it is important to inform your doctor about all the medications you are currently taking before starting Mycoplasm M 500 therapy.For further information:\nEmail: info@sterispharma.com / contact@sterispharma.com\nCall/WhatsApp: 7877551268, 7849827488\nORDER Now: \n\n\n\n\nMycophenolate mofetil 500 mg stands as a cornerstone in modern immunosuppressive therapy, primarily designed to prevent organ transplant rejection in kidney, heart, and liver recipients. As a prodrug, it rapidly converts to its active form, mycophenolic acid (MPA), which selectively targets the proliferation of T and B lymphocytes—key players in immune responses that can attack transplanted organs. This medication, available in convenient 500 mg tablets, offers reliable protection against acute rejection episodes, making it an essential component in post-transplant regimens worldwide.​\n\nProduct Uses\nMycophenolate mofetil 500 mg finds its primary application in solid organ transplantation, where it helps maintain long-term graft survival. For kidney transplant patients, it is typically administered alongside corticosteroids and calcineurin inhibitors like cyclosporine or tacrolimus to suppress the immune system's overreaction to the new organ. In heart and liver transplants, it plays a similar role, reducing the incidence of rejection by inhibiting antibody production and cell-mediated immunity.​\n\nBeyond transplants, healthcare providers increasingly use mycophenolate mofetil 500 mg for various autoimmune conditions. It effectively manages lupus nephritis by curbing inflammation in the kidneys, showing superior efficacy over traditional therapies in preserving renal function. Rheumatoid arthritis patients benefit from its ability to dampen joint inflammation, while those with dermatomyositis or scleroderma experience reduced skin and muscle involvement. Off-label, it treats inflammatory bowel diseases like Crohn's disease and even certain skin disorders such as pemphigus vulgaris, where immune-mediated blistering threatens quality of life.​\n\nKey Benefits\nThe therapeutic advantages of mycophenolate mofetil 500 mg extend far beyond basic immunosuppression, offering patients enhanced outcomes and improved daily living.\n\nSuperior Graft Protection: Clinical data highlight reduced acute rejection rates by up to 50% when combined with standard regimens, leading to better long-term organ function and survival.​\n\nSelective Lymphocyte Targeting: By depleting guanosine nucleotides in T and B cells via inosine monophosphate dehydrogenase (IMPDH) inhibition, it spares other cell types, minimizing broad toxicity seen with older immunosuppressants.​\n\nAnti-Inflammatory Effects: MPA inhibits adhesion molecule glycosylation, preventing lymphocyte recruitment to inflamed sites, which alleviates symptoms in autoimmune flares.​\n\nOral Convenience: The 500 mg formulation allows flexible dosing—typically 1 gram twice daily—without the need for injections, improving patient adherence.​\n\nVersatility Across Conditions: Proven efficacy in lupus, vasculitis, and myositis expands its utility, often allowing steroid dose reduction and fewer relapses.​\n\nCardiovascular and Anticancer Potential: Emerging evidence suggests it delays graft atherosclerosis by reducing lipid oxidation and may hinder tumor progression in certain malignancies due to its impact on nucleotide synthesis.​\n\nThese benefits translate to fewer hospital readmissions, better quality of life, and cost savings in long-term care for transplant and autoimmune patients.​\n\nSide Effects\nWhile mycophenolate mofetil 500 mg provides robust immunosuppression, it carries risks typical of this drug class, necessitating vigilant monitoring.\n\nCommon side effects affect the gastrointestinal tract most prominently, with nausea, vomiting, diarrhea, and abdominal pain occurring in over 30% of users. These often improve with dose adjustments or enteric-coated alternatives, but hydration and antiemetics help manage them effectively.​\n\nHematologic issues like leukopenia, anemia, and thrombocytopenia arise due to bone marrow suppression, requiring regular complete blood counts—weekly initially, then monthly. Infections pose a significant threat, as suppressed immunity increases susceptibility to viral (e.g., CMV), bacterial, and fungal pathogens; prophylactic antivirals are standard.​\n\nLess frequent but notable effects include hypertension, tremor, insomnia, and elevated liver enzymes. Women face heightened risks of congenital malformations if used during pregnancy, mandating effective contraception and pregnancy testing. Rare severe reactions encompass progressive multifocal leukoencephalopathy (PML) from JC virus reactivation and hypersensitivity syndromes.​\n\nDosage and Administration Notes\nStandard dosing for renal transplants involves 1 gram (two 500 mg tablets) twice daily, starting within 72 hours post-surgery, with adjustments for renal impairment. Hepatic transplant patients may require higher initial doses due to metabolism differences. Always take on an empty stomach with water to optimize absorption, avoiding antacids that bind MPA.​\n\nPrecautions and Interactions\nPatients must avoid live vaccines, report fevers promptly, and undergo TB screening pre-treatment. Drug interactions with azathioprine, cholestyramine, or rifampin can alter levels, so pharmacists review regimens closely. Regular monitoring of MPA blood levels ensures therapeutic efficacy without toxicity.​\n\nConclusion\nMycophenolate mofetil 500 mg emerges as a transformative immunosuppressive agent, safeguarding transplanted organs and taming autoimmune storms with its precise mechanism of lymphocyte suppression and anti-inflammatory prowess. By delivering key benefits like reduced rejection, versatile applications, and manageable administration, it empowers patients to reclaim normalcy post-transplant or amid chronic illness. Despite potential side effects, proactive monitoring and personalized dosing mitigate risks, underscoring its value in contemporary medicine. For those navigating transplant recovery or autoimmune challenges, this medication offers hope and stability, backed by decades of clinical validation.\n\n", "price": 775.0, "discountamount": 256.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "part", "Call", "harm", "risk", "Email", "heart", "ORDER", "nausea", "kidney", "dosage", "doctor", "vomiting", "WhatsApp", "Patients", "diarrhea", "rejection", "infections", "500mg dose", "combination", "information", "sterisonline", "proliferation", "B lymphocytes", "abdominal pain", "pregnant women", "immune response", "developing fetus", "other medications", "liver transplants", "other complications", "healthcare provider", "Common side effects", "organ transplantation", "Mycophenolate mofetil", "immunosuppressive drug", "Mycoplasm M 500 therapy", "healthcare professional", "other immunosuppressants", "immunosuppressive effects", "potential adverse effects", "optimal therapeutic outcomes", "gastrointestinal disturbances", "comprehensive transplant treatment regimen" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1472, "imageuri": "https://productimages.withfloats.com/actual/6661a57fdd39d2ccddbc3bb9.jpg", "tileimageuri": "https://productimages.withfloats.com/tile/6661a57fdd39d2ccddbc3bb9.jpg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-06T12:03:09.216Z", "updatedon": "2026-03-12T08:00:39.14Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//mycophenolate-mofetil-500mg/1472", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MYCOPLASM M 500", "category": "NEPHROLOGYRANGE", "tags": [ "MYCOPLASM M 500", "Mycophenolate mofetil (500mg)", "Mycophenolate mofetil 500 mg tablet", "Mycophenolate mofetil 500 mg price", "Mycophenolate mofetil 500 mg dosage", "Mycophenolate mofetil uses", "Mycophenolate mofetil side effects", "mycophenolate mofetil 500mg tablet uses", "mycophenolate mofetil 500mg dosage for kidney transplant", "mycophenolate mofetil 500mg for autoimmune disease" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "665ef5bda743fd235821deeb", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "gliclazide 80 mg metformin 500 mg", "description": "GLICLAGLAZE M 80 \ngliclazide (80 mg), metformin (500 mg)\nIntroduction\nGLICLAGLAZE M 80 is a specialized medication formulated for individuals diagnosed with Type 2 diabetes, aiming to enhance blood sugar regulation. This oral medication combines Gliclazide (80 mg) with Metformin (500 mg), two effective antidiabetic agents that provide a synergistic effect to control high blood sugar.\n\nMechanism of Action\n\nGliclazide (80 mg): Belonging to the sulfonylurea class, gliclazide works by increasing insulin secretion from the pancreatic beta cells. It promotes a decrease in blood glucose levels and enhances the action of insulin in the body. Additionally, Gliclazide improves blood flow and has protective effects against the vascular complications of diabetes.\nMetformin (500 mg): Metformin reduces hepatic glucose production and improves insulin sensitivity by enhancing peripheral glucose uptake, particularly in muscle cells. This action helps lower blood glucose levels without the risk of inducing hypoglycemia and is associated with a potential reduction in body weight.\nBenefits\nGLICLAGLAZE M 80 offers a robust approach to managing Type 2 diabetes by targeting different aspects of the disease. The combination of Gliclazide and Metformin in this medication helps to control blood sugar more effectively than either component alone, potentially lowering the patient's risk of diabetes-related complications.\n\nDosage and Administration\n\nDosage: The starting dose should be adjusted based on the patient’s previous medication regimen, effectiveness, and tolerability. Dose adjustments should be made based on glycemic control, as assessed by regular monitoring of blood glucose levels.\nAdministration: It is recommended to take GLICLAGLAZE M 80 with meals to maximize drug absorption and minimize potential gastrointestinal side effects.\nSide Effects\nPotential side effects of GLICLAGLAZE M 80 include gastrointestinal symptoms like nausea and diarrhea, which usually improve over time. The risk of hypoglycemia exists but is moderated by the inclusion of metformin.\n\nConclusion\nGLICLAGLAZE M 80 represents an effective treatment solution for managing Type 2 diabetes, combining two powerful antidiabetic agents to improve glycemic control and reduce the risk of diabetes complications. Patients should maintain regular consultations with their healthcare provider to tailor their treatment plan according to their specific needs, ensuring the best possible outcomes in diabetes management.\nFor further information:\nEMAIL: info@sterispharma.com / contact@sterispharma.com \n Order Now\n\n\n\n\n\n\n", "price": 137.0, "discountamount": 41.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "risk", "time", "Order", "meals", "EMAIL", "nausea", "500 mg", "Action", "patient", "disease", "diarrhea", "Benefits", "decrease", "Mechanism", "Metformin", "component", "inclusion", "Conclusion", "blood flow", "gliclazide", "individuals", "information", "body weight", "combination", "Introduction", "muscle cells", "tolerability", "sterispharma", "hypoglycemia", "sterisonline", "starting dose", "effectiveness", "CALL/WHATSAPP", "GLICLAGLAZE M", "treatment plan", "specific needs", "Type 2 diabetes", "oral medication", "robust approach", "drug absorption", "high blood sugar", "Dose adjustments", "glycemic control", "different aspects", "insulin secretion", "regular monitoring", "sulfonylurea class", "synergistic effect", "protective effects", "healthcare provider", "insulin sensitivity", "potential reduction", "diabetes management", "blood glucose levels", "regular consultations", "pancreatic beta cells", "Administration Dosage", "best possible outcomes", "blood sugar regulation", "Potential side effects", "specialized medication", "diabetes complications", "vascular complications", "gastrointestinal symptoms", "peripheral glucose uptake", "hepatic glucose production", "previous medication regimen", "effective treatment solution", "diabetes-related complications", "two powerful antidiabetic agents", "two effective antidiabetic agents", "potential gastrointestinal side effects" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1287, "imageuri": "https://productimages.withfloats.com/actual/665ef5c0ca75628a5853ff45.png", "tileimageuri": "https://productimages.withfloats.com/tile/665ef5c0ca75628a5853ff45.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-04T11:08:45.584Z", "updatedon": "2026-03-13T05:37:48.45Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//gliclazide-80-mg-metformin-500-mg/1287", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "GLICLAGLAZE M 80 ", "category": "DIABETIC RANGE", "tags": [ "gliclazide 80 mg metformin 500 mg tablet uses", "gliclazide 80 mg metformin 500 mg dosage for diabetes", "gliclazide metformin 80 mg 500 mg side effects", "gliclazide metformin 80 mg 500 mg how it works" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false } ], "hasmoreitems": false, "isapirequest": false, "totalresults": 27, "query": null, "floatingpoint": null }