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{ "products": [ { "_id": "6a460bf90c11f3c74a816c87", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "methylprednisolone sodium succinate for injection usp", "description": "Methylprednisolone Sodium Succinate for Injection USP is a fast-acting corticosteroid administered intravenously or intramuscularly to control severe inflammation, allergic reactions, and autoimmune flare-ups. It works by rapidly suppressing the immune and inflammatory response and is used in hospital or clinical settings for acute conditions such as severe asthma attacks, anaphylaxis, autoimmune disease flares, and spinal cord injury protocols. It is a Schedule H prescription drug administered only under medical supervision.\n\nWhat Is Methylprednisolone Sodium Succinate for Injection USP?\n\nMethylprednisolone Sodium Succinate for Injection USP is a water-soluble, injectable corticosteroid used for rapid control of severe inflammatory, allergic, and autoimmune conditions. It is manufactured to United States Pharmacopeia (USP) standards and is typically administered by a healthcare professional via intravenous (IV) or intramuscular (IM) route when fast, high-potency anti-inflammatory or immunosuppressive action is required — situations where oral steroids act too slowly or oral intake isn't feasible.\n\nHow It Works\n\nMethylprednisolone sodium succinate is a synthetic glucocorticoid that acts rapidly once reconstituted and injected.\n\n\nBinds glucocorticoid receptors – enters cells and binds intracellular receptors that regulate inflammatory gene expression.\nSuppresses inflammatory mediators – reduces production of prostaglandins, leukotrienes, and cytokines responsible for swelling, redness, and pain.\nStabilizes cell membranes – reduces capillary permeability, limiting fluid leakage and tissue swelling at the site of inflammation.\nDampens immune overactivity – suppresses lymphocyte and macrophage activity, calming autoimmune or allergic overreactions.\nDelivers rapid systemic action – because it's water-soluble and given IV/IM, onset of anti-inflammatory effect is significantly faster than oral steroids.\n\n\nClinical Indications\n\nConditionWhy Methylprednisolone Injection Is UsedSevere Allergic Reactions / AnaphylaxisRapidly controls swelling, airway inflammation, and allergic cascadeAcute Asthma Exacerbation / COPD FlareReduces airway inflammation when inhalers alone are insufficientAutoimmune Disease Flares (Lupus, Rheumatoid Arthritis)High-dose pulse therapy to control acute flaresSpinal Cord Injury (acute, under specialist protocol)Used in specific clinical protocols to limit secondary inflammationSevere Dermatologic ReactionsControls widespread inflammatory skin reactionsPost-Transplant / Organ Rejection ManagementUsed as part of immunosuppressive regimens\n\nDosage & Administration\n\nParameterRecommendationTypical Adult Dose10–40 mg IV, may range up to 30 mg/kg in high-dose pulse therapy for specific conditionsRouteIntravenous (IV) injection/infusion or Intramuscular (IM) injectionFrequencyAs directed by the treating physician; often single dose or short tapering courseReconstitutionMust be reconstituted only with the accompanying diluent as per product insert, immediately before useAdministration SettingHospital, clinic, or under direct medical/nursing supervision onlyDurationShort-term acute use unless otherwise directed; long-term use requires specialist monitoring\n\nThis is a Schedule H prescription-only medicine. Dosage must be determined and administered by a qualified healthcare professional.\n\nPrecautions\n\n\nTo be administered only by or under the supervision of a healthcare professional.\nNot for self-administration or home use.\nInform the doctor of any active infections, as corticosteroids can mask symptoms and suppress immune response.\nUse with caution in patients with diabetes, hypertension, peptic ulcer disease, osteoporosis, or psychiatric history.\nAvoid live vaccines during treatment due to immunosuppressive effects.\nPregnant or breastfeeding patients should use only under strict medical guidance.\nAbrupt discontinuation after prolonged use should be avoided; tapering may be required as advised by the physician.\n\n\nPossible Side Effects\n\nMost side effects relate to the drug's systemic corticosteroid action and are monitored by the administering clinician:\n\n\nElevated blood sugar levels\nFluid retention, increased blood pressure\nMood changes, insomnia, or restlessness\nNausea or gastrointestinal discomfort\nIncreased susceptibility to infection\nInjection site reactions\n\n\nSerious side effects requiring immediate medical attention include severe allergic reaction, signs of infection (fever, chills), significant mood or behavioral changes, unusual swelling, or vision disturbances. Because this is administered in a clinical setting, the healthcare team monitors for these actively.\n\nComparison: Methylprednisolone vs. Other Injectable Corticosteroids\n\nDrugRelative PotencyCommon Use CaseRouteMethylprednisolone Sodium SuccinateHighAcute severe inflammation, autoimmune flaresIV/IMHydrocortisone Sodium SuccinateLowerAdrenal insufficiency, milder acute inflammationIV/IMDexamethasone Sodium PhosphateVery HighCerebral edema, severe allergic/inflammatory conditionsIV/IMBetamethasone Sodium PhosphateHighAllergic and inflammatory conditions, fetal lung maturityIV/IMTriamcinolone AcetonideModerate (depot)Localized/intra-articular inflammationIM/Intra-articular\n\nKey Statistics\n\nStatisticData PointSourceOnset of anti-inflammatory action after IV administrationWithin 1–2 hours for measurable effectClinical pharmacology references, USP monographUse in acute severe asthma protocolsRecommended as part of systemic corticosteroid therapy in emergency guidelinesGlobal Initiative for Asthma (GINA) guidelinesHospital use in anaphylaxis managementIncluded as an adjunct in anaphylaxis treatment protocols alongside epinephrineWorld Allergy Organization guidanceHigh-dose pulse therapy applicationUsed in select autoimmune flare protocols under specialist supervisionPublished rheumatology treatment guidelines\n\nExpert Insight\n\n[Insert verified physician or clinical pharmacologist commentary here — Claude has not fabricated a quote. Recommend sourcing a short, attributable statement from a Steris Healthcare medical advisor or a cited clinical guideline before publishing.]\n\nConclusion\n\nMethylprednisolone Sodium Succinate for Injection USP is a high-potency, fast-acting corticosteroid reserved for situations where rapid control of severe inflammation, allergic reaction, or autoimmune flare is essential. Administered only under clinical supervision, it plays a critical role in emergency and hospital-based treatment protocols — from anaphylaxis and acute asthma to autoimmune disease management. As a Schedule H medicine, it must never be self-administered; dosage, route, and duration should always be determined by a qualified physician based on the patient's condition. For pharmacopoeia-grade quality and reliable hospital supply, source this injection through a WHO-GMP certified manufacturer.\n\nPrescription only – consult your doctor.\n\n\nHigh-Ranking FAQs (Google Search & Voice Search Optimized)\n\n1. What is methylprednisolone sodium succinate injection used for?\nIt is used to rapidly control severe inflammation, allergic reactions, and autoimmune flare-ups, such as anaphylaxis, acute asthma attacks, and lupus or rheumatoid arthritis flares. It is administered under medical supervision in hospital or clinical settings.\n\n2. Is methylprednisolone injection a steroid?\nYes, it is a synthetic corticosteroid (glucocorticoid) that works by suppressing inflammatory and immune responses in the body, providing rapid relief in acute, severe conditions.\n\n3. How is methylprednisolone sodium succinate injection given?\nIt is given by a healthcare professional via intravenous (IV) or intramuscular (IM) injection, after being reconstituted with the correct diluent immediately before administration. It is not for self-injection or home use.\n\n4. How fast does methylprednisolone injection start working?\nBecause it is water-soluble and given directly into the bloodstream or muscle, measurable anti-inflammatory effects typically begin within one to two hours of administration.\n\n5. What are the side effects of methylprednisolone injection?\nCommon effects include elevated blood sugar, fluid retention, mood changes, and increased infection risk. These are monitored by the administering healthcare team, and serious reactions are managed promptly in a clinical setting.\n\n6. Is methylprednisolone sodium succinate injection available without a prescription?\nNo. It is a Schedule H prescription-only medicine that must be administered by or under the direct supervision of a qualified healthcare professional.\n\n7. What is the difference between methylprednisolone and dexamethasone injection?\nBoth are injectable corticosteroids, but dexamethasone has a longer duration of action and higher relative potency, while methylprednisolone is often preferred for acute pulse therapy and shorter-acting systemic control. The choice depends on the clinical scenario and physician judgment.\n\n8. Can methylprednisolone injection be used in pregnancy?\nIt may be used in pregnancy only when clearly necessary and under strict medical supervision, as the treating physician will weigh the benefits against potential risks for the specific condition being treated.", "price": 47.0, "discountamount": 19.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2465, "imageuri": "https://productimages.withfloats.com/actual/6a460bfb9f5529389b8b15b8.png", "tileimageuri": "https://productimages.withfloats.com/tile/6a460bfb9f5529389b8b15b8.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-07-02T06:58:01.631Z", "updatedon": "2026-07-02T06:58:01.631Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/methylprednisolone-sodium-succinate-for-injection-usp/2465", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "METHIDENOSOLE 40 INJ", "category": "GENERAL RANGE", "tags": [ "methylprednisolone sodium succinate injection uses", "methylprednisolone sodium succinate injection uses in hindi", "methylprednisolone sodium succinate", "methylprednisolone sodium succinate injection", "inj methylprednisolone sodium succinate", "methylprednisolone sodium succinate uses in hindi", "methylprednisolone sodium succinate for injection", "methylprednisolone sodium succinate injection usp" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69cbc41faf13b43636b170d0", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Everolimus Tablets 0.5 mg", "description": "EVERENOLIMUS 0.5 is a prescription medication containing Everolimus 0.5 mg tablets, a potent mTOR (mammalian target of rapamycin) inhibitor used in advanced medical treatments. This medicine works by regulating cell growth, division, and immune system activity, making it effective in both oncology and transplant care.\nEverolimus has become a crucial therapeutic option for patients requiring targeted cancer therapy or immunosuppression after organ transplantation. Its dual functionality—controlling abnormal cell proliferation and preventing organ rejection—makes it a preferred choice among healthcare providers.\nIn India, EVERENOLIMUS 0.5 is increasingly prescribed for specific cancers, post-transplant care, and rare disorders like tuberous sclerosis complex. Its oral tablet form allows convenient administration while maintaining effective systemic action.\n\nUses of EVERENOLIMUS 0.5\n\nEVERENOLIMUS 0.5 is indicated for a range of serious medical conditions:\n1. Organ Transplantation\nHelps prevent rejection of kidney and liver transplants\nMaintains graft survival by suppressing the immune response\n2. Cancer Treatment\nHormone receptor-positive, HER2-negative advanced breast cancer\nAdvanced kidney cancer (renal cell carcinoma)\nNeuroendocrine tumors (pancreas, lungs, gastrointestinal tract)\n3. Tuberous Sclerosis Complex (TSC)\nManages non-cancerous tumors such as subependymal giant cell astrocytoma (SEGA)\nReduces tumor growth in vital organs\n4. Other Rare Conditions\nCertain types of cardiac or renal vascular growth disorders, under specialist supervision\nBenefits of EVERENOLIMUS 0.5\n1. Dual Therapeutic Action\nOffers immunosuppressive benefits for transplant patients\nProvides targeted anti-cancer activity to control abnormal cell growth\n2. Improved Transplant Outcomes\nReduces the risk of graft rejection\nEnsures long-term functionality of transplanted organs\n3. Targeted Cancer Therapy\nFocuses on specific cellular pathways\nMinimizes damage to healthy cells compared to conventional chemotherapy\n4. Slows Disease Progression\nEffective in advanced cancers and benign tumors\nControls disease symptoms and improves patient quality of life\n5. Convenient Oral Formulation\nEasy to take as a tablet without injections\nEnables consistent and controlled drug delivery\n6. Enhances Long-Term Management\nRegular use supports chronic disease control\nReduces hospitalization and complication rates\nDosage of EVERENOLIMUS 0.5\n\nThe exact dosage depends on the patient’s condition, weight, and response to therapy. It must be determined by a healthcare professional.\n\nGeneral Guidelines:\nTypically taken once daily\nSwallow the tablet whole with water\nCan be taken with or without food, but maintain consistency\nMonitoring Requirements:\nRegular blood tests to check kidney and liver function\nMonitoring drug levels ensures effectiveness and safety\nMissed Dose:\nTake the missed dose as soon as possible\nIf it is near the next scheduled dose, skip the missed dose\nDo not double the dose\n\nSide Effects of EVERENOLIMUS 0.5\n\nEVERENOLIMUS 0.5 may cause side effects, which can range from mild to serious.\nCommon Side Effects:\nFatigue and weakness\nNausea or vomiting\nMouth ulcers\nDiarrhea\nLess Common Side Effects:\nEdema (swelling in hands or feet)\nIncreased blood sugar and cholesterol levels\nSkin rash\nSerious Side Effects:\nIncreased risk of infections due to suppressed immunity\nLung inflammation (non-infectious pneumonitis)\nImpaired kidney or liver function\nDelayed wound healing\nWhen to Seek Medical Attention:\nPersistent fever or signs of infection\nShortness of breath or chest pain\nSevere weakness, dizziness, or swelling\nUnusual bleeding or bruising\nPrecautions and Warning\n1. Infection Risk\nSuppressed immunity increases susceptibility to infections\nAvoid exposure to people with contagious diseases\n2. Liver and Kidney Function\nRegular tests are necessary to monitor organ health\n3. Vaccinations\nAvoid live vaccines during treatment\nConsult your doctor before any vaccination\n4. Drug Interactions\nInform your doctor about all medications, including antibiotics, antifungals, and supplements\n5. Pregnancy and Contraception\nNot recommended during pregnancy\nEffective contraception is advised during and after treatment\n6. Surgery and Wound Healing\nInform your doctor before undergoing surgery\nWound healing may be delayed due to Everolimus effects\n7. Sun Protection\nIncreased sensitivity to sunlight\nUse sunscreen and protective clothing\n\nConclusion\n\nEVERENOLIMUS 0.5 (Everolimus Tablets 0.5 mg) is a highly effective oral medication that offers dual benefits for cancer patients and organ transplant recipients. Its targeted mechanism ensures precise therapeutic action while minimizing unnecessary side effects.\nBy preventing organ rejection, controlling tumor growth, and improving long-term outcomes, EVERENOLIMUS 0.5 has become a trusted choice in modern clinical practice. Patients in India seeking reliable, medically supervised care for complex conditions can benefit greatly from this advanced therapy.\nStrict adherence to dosage, regular monitoring, and medical supervision are essential for safe and effective use. Combined with lifestyle and dietary guidance, EVERENOLIMUS 0.5 supports improved quality of life and enhanced clinical outcomes.", "price": 643.0, "discountamount": 193.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2359, "imageuri": "https://productimages.withfloats.com/actual/69cbc421595f848aedb0807c.png", "tileimageuri": "https://productimages.withfloats.com/tile/69cbc421595f848aedb0807c.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-03-31T12:54:55.448Z", "updatedon": "2026-04-14T12:54:29.458Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//everolimus-tablets-0-5-mg/2359", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "EVERENOLIMUS 0.5", "category": "Oncology", "tags": [ "everolimus tablets 0.5 mg uses", "everolimus 0.5 mg dosage and benefits", "everolimus 0.5 mg side effects and precautions", "everolimus 0.5 mg mechanism of action", "everolimus 0.5 mg tablet guide", "everolimus 0.5 mg price in India", "everolimus tablets bulk supplier", "best everolimus tablets 0.5 mg price and uses India", "buy everolimus 0.5 mg tablets online at best price", "everolimus tablets for organ transplant patients India" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6661a73687f0960e14a2c739", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "mycophenolate sodium 360 mg", "description": "MYCOPLASM S 360 \nMycophenolate sodium 360 mg is an essential immunosuppressant medication designed to prevent organ transplant rejection, particularly for kidney, heart, and liver transplants. As the sodium salt of mycophenolic acid, it delivers 360 mg of the active moiety per tablet, providing targeted immune suppression to help patients maintain their new organs long-term. This product stands out for its enteric-coated formulation, which enhances gastrointestinal tolerability compared to other forms, making it a preferred choice in post-transplant care regimens.​\n\nUses of Mycophenolate Sodium 360 mg\nMycophenolate sodium 360 mg primarily serves as a prophylactic agent against acute rejection in adult and pediatric patients receiving allogeneic renal, cardiac, or hepatic transplants. It works alongside other immunosuppressants like cyclosporine and corticosteroids to create a balanced regimen that minimizes the risk of graft loss. Clinically, it proves effective in de novo transplant recipients, where starting therapy early post-surgery significantly reduces rejection episodes. Beyond transplants, off-label applications include managing refractory autoimmune conditions such as lupus nephritis or myasthenia gravis, where immune overactivity damages tissues.​\n\nThe drug targets the proliferation of T- and B-lymphocytes, key players in immune responses that can attack transplanted organs. In renal transplant patients, for instance, it helps preserve kidney function by curbing antibody-mediated rejection. Its role extends to maintenance therapy, where consistent dosing sustains immunosuppression without excessive toxicity. Healthcare providers often adjust it based on patient response and trough levels of the active metabolite, mycophenolic acid (MPA), ensuring optimal therapeutic outcomes.​\n\nKey Benefits of Mycophenolate Sodium 360 mg\nMycophenolate sodium 360 mg offers several advantages that make it a cornerstone in transplant medicine. One primary benefit is its selective inhibition of lymphocyte proliferation, sparing other cell types and reducing broad-spectrum immunosuppression risks. This leads to fewer opportunistic infections compared to older agents like azathioprine. The enteric coating minimizes upper GI upset, improving patient compliance—studies show higher adherence rates with this formulation.​\n\nEnhanced Graft Survival: Prolongs organ viability by effectively suppressing cell-mediated and humoral immunity, with clinical data showing reduced biopsy-proven rejection rates.\n\nImproved Tolerability: Lower incidence of nausea and diarrhea due to delayed-release technology, allowing twice-daily dosing without food restrictions.\n\nFlexible Dosing: Equivalent to 720 mg mycophenolate mofetil, but with predictable MPA exposure via enterohepatic recirculation for steady-state efficacy.\n\nPediatric Suitability: Approved for children over 2 years in renal transplants, supporting growth without compromising safety.\n\nCost-Effective Long-Term Option: Balances efficacy and side effect profile, potentially lowering overall healthcare costs from fewer rejections or hospitalizations.​\n\nPatients experience better quality of life, with sustained energy levels and fewer interruptions from acute rejection crises. Its metabolism to MPA via liver glucuronidation ensures reliable pharmacokinetics, even in patients with mild renal impairment.​\n\nSide Effects of Mycophenolate Sodium 360 mg\nWhile highly effective, mycophenolate sodium 360 mg carries risks typical of immunosuppressants, necessitating vigilant monitoring. Common adverse effects stem from its impact on rapidly dividing cells, particularly in the gut and bone marrow.\n\nCommon Side Effects\nGastrointestinal issues like diarrhea, nausea, vomiting, and abdominal pain, affecting up to 30-50% of users.\n\nHeadache, insomnia, and tremor, often mild and transient.\n\nInfections such as urinary tract or respiratory, due to moderated immunity.\n\nHypertension or peripheral edema, manageable with supportive care.\n\nLeukopenia or anemia, requiring periodic blood counts.​\n\nSerious Side Effects\nSevere myelosuppression leading to neutropenia or thrombocytopenia, which can increase infection or bleeding risks.\n\nProgressive multifocal leukoencephalopathy (PML), a rare brain infection linked to JC virus reactivation.\n\nGastrointestinal perforation or bleeding, especially in at-risk patients.\n\nIncreased malignancy risk, including lymphoma or skin cancers, over long-term use.\n\nHypersensitivity reactions like rash or anaphylaxis.​\n\nRegular complete blood counts, viral monitoring (e.g., CMV, BK virus), and skin exams mitigate these risks. Dose reductions or discontinuation may be needed if counts drop significantly.​\n\nMechanism of Action\nMycophenolate sodium 360 mg rapidly hydrolyzes to mycophenolic acid (MPA), a potent, reversible, non-competitive inhibitor of inosine-5'-monophosphate dehydrogenase (IMPDH). This enzyme catalyzes the rate-limiting step in de novo guanine nucleotide synthesis, depleting guanosine nucleotides essential for T- and B-cell DNA replication. Lymphocytes, reliant on this pathway, undergo proliferation arrest, suppressing both cell-mediated immunity and antibody production.​\n\nMPA also hinders glycosylation of adhesion molecules on lymphocytes and monocytes, impeding their migration to graft sites. It reduces nitric oxide production in macrophages without affecting endothelial cells, curbing inflammation. Enterohepatic recirculation of the glucuronide metabolite (MPAG) prolongs MPA exposure, enhancing efficacy. Protein binding to albumin (around 97%) ensures targeted delivery, with clearance primarily renal for the inactive form.​\n\nDosage and Administration Guidelines\nStandard dosing for renal transplant is 720 mg (two 360 mg tablets) twice daily, starting within 72 hours post-surgery. Adjustments occur for hepatic or cardiac transplants, often alongside cyclosporine. Therapeutic drug monitoring of MPA AUC (area under curve) optimizes levels between 30-60 mcg·h/mL. Take on an empty stomach for best absorption, though food has minimal impact due to the coating.​\n\nPrecautions and Warnings\nAvoid in pregnancy (Category D) due to teratogenicity—use contraception and regular pregnancy tests. Contraindicated in active untreated infections. Monitor for GI bleeding in ulcerative colitis patients. Drug interactions with antacids, cholestyramine, or rifampin alter MPA levels. Live vaccines are prohibited.​\n\nConclusion\nMycophenolate sodium 360 mg represents a vital advancement in transplant immunosuppression, offering robust protection against rejection with a favorable benefit-risk profile. Its targeted action on lymphocytes, combined with improved GI tolerance, empowers patients to thrive post-transplant. By integrating it into comprehensive regimens with close monitoring, healthcare teams maximize graft success and patient well-being. Always consult a specialist for personalized guidance to harness its full potential safely.\nEmail: info@sterispharma.com / contact@sterispharma.com\nCall/WhatsApp: 7877551268, 7849827488\nORDER Now: \nhttps://www.sterisonline.com/product/mycoplasm-s-360-133670\n\n\n\n\n\n\n", "price": 767.0, "discountamount": 567.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "dose", "risk", "body", "part", "ORDER", "360mg", "Email", "cells", "dosage", "nausea", "vomiting", "schedule", "headache", "strength", "WhatsApp", "diarrhea", "activity", "rejection", "treatment", "infections", "supplements", "information", "MYCOPLASM S", "sterispharma", "sterisonline", "stomach pain", "blood counts", "immune system", "complications", "liver problems", "liver function", "other medications", "Regular monitoring", "medical conditions", "healthcare provider", "Common side effects", "Serious side effects", "white blood cell count", "potential drug interactions", "optimal therapeutic effects", "combination therapy regimen", "organ transplant recipients", "Mycophenolate Sodium therapy", "other immunosuppressive drugs" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1474, "imageuri": "https://productimages.withfloats.com/actual/6661a739c749b7962dbc08c6.jpg", "tileimageuri": "https://productimages.withfloats.com/tile/6661a739c749b7962dbc08c6.jpg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-06T12:10:30.488Z", "updatedon": "2026-03-12T08:02:36.733Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//mycophenolate-sodium-360-mg/1474", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MYCOPLASM S 360 ", "category": "Oncology", "tags": [ "MYCOPLASM S 360", "Mycophenolate sodium (360mg)", "Mycophenolate sodium 360 mg price", "Mycophenolate sodium 360 mg brands", "Mycophenolate sodium 360 mg side effects", "Myfortic 360 alternative", "Myfortic 500" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6661a57d8da3a81d5c6a17dd", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Mycophenolate mofetil 500mg", "description": "MYCOPLASM M 500\nMycophenolate mofetil (500mg)\nMycoplasm M 500 is a medication containing Mycophenolate Mofetil in a 500mg dose. Mycophenolate Mofetil is an immunosuppressive drug used to prevent rejection in organ transplantation, particularly kidney, heart, and liver transplants. It works by inhibiting the proliferation of T and B lymphocytes, which are involved in the immune response that leads to rejection.\n\nThis medication is typically prescribed in combination with other immunosuppressants as part of a comprehensive transplant treatment regimen. It is important to take Mycoplasm M 500 exactly as prescribed by your healthcare provider to ensure optimal therapeutic outcomes and to minimize the risk of rejection or other complications.\n\nCommon side effects of Mycophenolate Mofetil may include gastrointestinal disturbances such as nausea, vomiting, diarrhea, and abdominal pain. It can also increase the risk of infections due to its immunosuppressive effects. Patients should be monitored regularly by their healthcare provider while taking this medication to assess for any potential adverse effects and to adjust the dosage as needed.\n\nMycoplasm M 500 should not be used in pregnant women or those planning to become pregnant without consulting a healthcare professional, as it can cause harm to the developing fetus. Additionally, it may interact with other medications, so it is important to inform your doctor about all the medications you are currently taking before starting Mycoplasm M 500 therapy.For further information:\nEmail: info@sterispharma.com / contact@sterispharma.com\nCall/WhatsApp: 7877551268, 7849827488\nORDER Now: \n\n\n\n\nMycophenolate mofetil 500 mg stands as a cornerstone in modern immunosuppressive therapy, primarily designed to prevent organ transplant rejection in kidney, heart, and liver recipients. As a prodrug, it rapidly converts to its active form, mycophenolic acid (MPA), which selectively targets the proliferation of T and B lymphocytes—key players in immune responses that can attack transplanted organs. This medication, available in convenient 500 mg tablets, offers reliable protection against acute rejection episodes, making it an essential component in post-transplant regimens worldwide.​\n\nProduct Uses\nMycophenolate mofetil 500 mg finds its primary application in solid organ transplantation, where it helps maintain long-term graft survival. For kidney transplant patients, it is typically administered alongside corticosteroids and calcineurin inhibitors like cyclosporine or tacrolimus to suppress the immune system's overreaction to the new organ. In heart and liver transplants, it plays a similar role, reducing the incidence of rejection by inhibiting antibody production and cell-mediated immunity.​\n\nBeyond transplants, healthcare providers increasingly use mycophenolate mofetil 500 mg for various autoimmune conditions. It effectively manages lupus nephritis by curbing inflammation in the kidneys, showing superior efficacy over traditional therapies in preserving renal function. Rheumatoid arthritis patients benefit from its ability to dampen joint inflammation, while those with dermatomyositis or scleroderma experience reduced skin and muscle involvement. Off-label, it treats inflammatory bowel diseases like Crohn's disease and even certain skin disorders such as pemphigus vulgaris, where immune-mediated blistering threatens quality of life.​\n\nKey Benefits\nThe therapeutic advantages of mycophenolate mofetil 500 mg extend far beyond basic immunosuppression, offering patients enhanced outcomes and improved daily living.\n\nSuperior Graft Protection: Clinical data highlight reduced acute rejection rates by up to 50% when combined with standard regimens, leading to better long-term organ function and survival.​\n\nSelective Lymphocyte Targeting: By depleting guanosine nucleotides in T and B cells via inosine monophosphate dehydrogenase (IMPDH) inhibition, it spares other cell types, minimizing broad toxicity seen with older immunosuppressants.​\n\nAnti-Inflammatory Effects: MPA inhibits adhesion molecule glycosylation, preventing lymphocyte recruitment to inflamed sites, which alleviates symptoms in autoimmune flares.​\n\nOral Convenience: The 500 mg formulation allows flexible dosing—typically 1 gram twice daily—without the need for injections, improving patient adherence.​\n\nVersatility Across Conditions: Proven efficacy in lupus, vasculitis, and myositis expands its utility, often allowing steroid dose reduction and fewer relapses.​\n\nCardiovascular and Anticancer Potential: Emerging evidence suggests it delays graft atherosclerosis by reducing lipid oxidation and may hinder tumor progression in certain malignancies due to its impact on nucleotide synthesis.​\n\nThese benefits translate to fewer hospital readmissions, better quality of life, and cost savings in long-term care for transplant and autoimmune patients.​\n\nSide Effects\nWhile mycophenolate mofetil 500 mg provides robust immunosuppression, it carries risks typical of this drug class, necessitating vigilant monitoring.\n\nCommon side effects affect the gastrointestinal tract most prominently, with nausea, vomiting, diarrhea, and abdominal pain occurring in over 30% of users. These often improve with dose adjustments or enteric-coated alternatives, but hydration and antiemetics help manage them effectively.​\n\nHematologic issues like leukopenia, anemia, and thrombocytopenia arise due to bone marrow suppression, requiring regular complete blood counts—weekly initially, then monthly. Infections pose a significant threat, as suppressed immunity increases susceptibility to viral (e.g., CMV), bacterial, and fungal pathogens; prophylactic antivirals are standard.​\n\nLess frequent but notable effects include hypertension, tremor, insomnia, and elevated liver enzymes. Women face heightened risks of congenital malformations if used during pregnancy, mandating effective contraception and pregnancy testing. Rare severe reactions encompass progressive multifocal leukoencephalopathy (PML) from JC virus reactivation and hypersensitivity syndromes.​\n\nDosage and Administration Notes\nStandard dosing for renal transplants involves 1 gram (two 500 mg tablets) twice daily, starting within 72 hours post-surgery, with adjustments for renal impairment. Hepatic transplant patients may require higher initial doses due to metabolism differences. Always take on an empty stomach with water to optimize absorption, avoiding antacids that bind MPA.​\n\nPrecautions and Interactions\nPatients must avoid live vaccines, report fevers promptly, and undergo TB screening pre-treatment. Drug interactions with azathioprine, cholestyramine, or rifampin can alter levels, so pharmacists review regimens closely. Regular monitoring of MPA blood levels ensures therapeutic efficacy without toxicity.​\n\nConclusion\nMycophenolate mofetil 500 mg emerges as a transformative immunosuppressive agent, safeguarding transplanted organs and taming autoimmune storms with its precise mechanism of lymphocyte suppression and anti-inflammatory prowess. By delivering key benefits like reduced rejection, versatile applications, and manageable administration, it empowers patients to reclaim normalcy post-transplant or amid chronic illness. Despite potential side effects, proactive monitoring and personalized dosing mitigate risks, underscoring its value in contemporary medicine. For those navigating transplant recovery or autoimmune challenges, this medication offers hope and stability, backed by decades of clinical validation.\n\n", "price": 775.0, "discountamount": 256.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "part", "Call", "harm", "risk", "Email", "heart", "ORDER", "nausea", "kidney", "dosage", "doctor", "vomiting", "WhatsApp", "Patients", "diarrhea", "rejection", "infections", "500mg dose", "combination", "information", "sterisonline", "proliferation", "B lymphocytes", "abdominal pain", "pregnant women", "immune response", "developing fetus", "other medications", "liver transplants", "other complications", "healthcare provider", "Common side effects", "organ transplantation", "Mycophenolate mofetil", "immunosuppressive drug", "Mycoplasm M 500 therapy", "healthcare professional", "other immunosuppressants", "immunosuppressive effects", "potential adverse effects", "optimal therapeutic outcomes", "gastrointestinal disturbances", "comprehensive transplant treatment regimen" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1472, "imageuri": "https://productimages.withfloats.com/actual/6661a57fdd39d2ccddbc3bb9.jpg", "tileimageuri": "https://productimages.withfloats.com/tile/6661a57fdd39d2ccddbc3bb9.jpg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-06T12:03:09.216Z", "updatedon": "2026-03-12T08:00:39.14Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//mycophenolate-mofetil-500mg/1472", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MYCOPLASM M 500", "category": "NEPHROLOGYRANGE", "tags": [ "MYCOPLASM M 500", "Mycophenolate mofetil (500mg)", "Mycophenolate mofetil 500 mg tablet", "Mycophenolate mofetil 500 mg price", "Mycophenolate mofetil 500 mg dosage", "Mycophenolate mofetil uses", "Mycophenolate mofetil side effects", "mycophenolate mofetil 500mg tablet uses", "mycophenolate mofetil 500mg dosage for kidney transplant", "mycophenolate mofetil 500mg for autoimmune disease" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6635ed538e18ce14f428c0c1", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Tofacitinib 11 mg", "description": "TACOTINIB ER 11 \nTACOTINIB ER 11 (Tofacitinib 11 mg Extended Release) – Comprehensive Product Overview\n\nTACOTINIB ER 11 contains Tofacitinib 11 mg in an extended-release formulation designed for convenient once-daily dosing. Tofacitinib belongs to a class of medicines known as Janus kinase (JAK) inhibitors. It works by modulating the immune system to reduce inflammation and control symptoms in certain autoimmune conditions. TACOTINIB ER 11 is prescribed under medical supervision to help patients manage chronic inflammatory diseases effectively and improve quality of life.\n\nWhat is Tofacitinib 11 mg?\n\nTofacitinib is an oral targeted synthetic disease-modifying anti-rheumatic drug (tsDMARD). Unlike traditional immunosuppressive therapies, it specifically blocks JAK enzymes involved in the inflammatory signaling pathway. By inhibiting these pathways, TACOTINIB ER 11 reduces the overactive immune response responsible for joint damage, swelling, pain, and other systemic symptoms.\n\nThe extended-release (ER) 11 mg formulation ensures a steady release of medication over 24 hours, maintaining consistent blood levels while improving convenience compared to twice-daily immediate-release options.\n\nIndications and Uses of TACOTINIB ER 11\n\nTACOTINIB ER 11 is commonly prescribed for the management of:\n\n1. Rheumatoid Arthritis (RA)\n\nA chronic autoimmune condition that causes inflammation in the joints, leading to pain, stiffness, swelling, and progressive joint damage. Tofacitinib helps reduce inflammation and slow structural damage.\n\n2. Psoriatic Arthritis (PsA)\n\nAn inflammatory arthritis associated with psoriasis. TACOTINIB ER 11 helps manage joint symptoms and improves physical function.\n\n3. Ulcerative Colitis (UC)\n\nA chronic inflammatory bowel disease affecting the colon. Tofacitinib may help reduce intestinal inflammation and induce remission in moderate to severe cases.\n\n4. Ankylosing Spondylitis (AS) (as advised by a physician)\n\nMay be used in selected patients where other treatments are not effective.\n\nTreatment should always be initiated and monitored by a qualified healthcare professional.\n\nHow TACOTINIB ER 11 Works\n\nTACOTINIB ER 11 targets intracellular signaling pathways involved in immune cell activation. By blocking Janus kinase enzymes (JAK1 and JAK3 primarily), it prevents the transmission of pro-inflammatory cytokine signals. This results in:\n\nReduced joint inflammation\n\nDecreased immune overactivity\n\nRelief from pain and stiffness\n\nSlowing of disease progression\n\nBecause it acts on immune pathways, regular medical monitoring is required during treatment.\n\nKey Benefits of TACOTINIB ER 11\n✔ Effective Inflammation Control\n\nReduces swelling, pain, and tenderness in affected joints or tissues.\n\n✔ Improved Physical Function\n\nEnhances mobility and daily activity performance in patients with rheumatoid or psoriatic arthritis.\n\n✔ Convenient Once-Daily Dosing\n\nExtended-release 11 mg formulation improves patient compliance.\n\n✔ Targeted Mechanism of Action\n\nSpecifically inhibits JAK pathways, offering a modern therapeutic approach.\n\n✔ Reduced Disease Progression\n\nHelps prevent long-term structural joint damage when used appropriately.\n\n✔ Oral Administration\n\nUnlike some biologic therapies, TACOTINIB ER 11 is taken orally, eliminating the need for injections.\n\nDosage and Administration\n\nThe usual recommended dose is one tablet (11 mg) once daily, or as prescribed by your physician.\n\nTablets should be swallowed whole with water.\n\nDo not crush, chew, or split the tablet.\n\nCan be taken with or without food.\n\nDosage adjustments may be required in patients with liver impairment, kidney problems, or when used alongside certain medications.\n\nPossible Side Effects of TACOTINIB ER 11\n\nLike all medications, TACOTINIB ER 11 may cause side effects. Not everyone experiences them, but it is important to be aware of potential risks.\n\nCommon Side Effects:\n\nUpper respiratory tract infections\n\nHeadache\n\nDiarrhea\n\nNausea\n\nIncreased cholesterol levels\n\nMild increase in liver enzymes\n\nSerious Side Effects:\n\nSerious infections (tuberculosis, bacterial, viral, or fungal infections)\n\nBlood clots (deep vein thrombosis or pulmonary embolism)\n\nCardiovascular events in high-risk individuals\n\nReduced white blood cell count\n\nIncreased risk of certain cancers (with long-term use)\n\nSeek immediate medical attention if you experience:\n\nPersistent fever\n\nShortness of breath\n\nChest pain\n\nSevere abdominal pain\n\nUnusual bruising or bleeding\n\nRegular blood tests are required to monitor liver function, cholesterol levels, and blood cell counts during treatment.\n\nPrecautions and Warnings\n\nBefore starting TACOTINIB ER 11, inform your doctor if you:\n\nHave a history of recurrent infections\n\nHave liver or kidney disease\n\nHave tuberculosis or hepatitis\n\nAre pregnant or planning pregnancy\n\nAre breastfeeding\n\nHave a history of blood clots or cardiovascular disease\n\nVaccinations should be updated before initiating therapy. Live vaccines are generally not recommended during treatment.\n\nDrug Interactions\n\nTACOTINIB ER 11 may interact with:\n\nStrong CYP3A4 inhibitors (e.g., certain antifungals)\n\nImmunosuppressive drugs\n\nBiologic DMARDs\n\nCertain antibiotics\n\nAlways inform your healthcare provider about all medications and supplements you are taking.\n\nStorage Instructions\n\nStore below 25°C in a dry place\n\nProtect from moisture and direct sunlight\n\nKeep out of reach of children\n\nWho Should Avoid TACOTINIB ER 11?\n\nThis medication may not be suitable for:\n\nPatients with active serious infections\n\nIndividuals with severe liver impairment\nPatients at high risk of blood clots without proper medical supervision\nA detailed medical evaluation is necessary before starting therapy.\n\nConclusion\nTACOTINIB ER 11 (Tofacitinib 11 mg Extended Release) is an advanced oral treatment option for managing moderate to severe autoimmune conditions such as rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. By targeting JAK pathways, it effectively reduces inflammation, improves mobility, and enhances overall quality of life.\n", "price": 795.0, "discountamount": 239.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "mg", "class", "headache", "response", "guidance", "monitoring", "medication", "TACOTINIB ER", "inflammation", "Janus kinase", "immune system", "joint function", "JAK) inhibitors", "sustained relief", "prescribed dosage", "healthcare provider", "psoriatic arthritis", "Common side effects", "rheumatoid arthritis", "extended-release formulation", "Tofacitinib Extended Release", "gastrointestinal disturbances", "upper respiratory tract infections" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1102, "imageuri": "https://productimages.withfloats.com/actual/6635ed8ae837fe0918c055ff.png", "tileimageuri": "https://productimages.withfloats.com/tile/6635ed8ae837fe0918c055ff.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-05-04T08:09:55.768Z", "updatedon": "2026-03-14T06:26:01.73Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//tofacitinib-11-mg/1102", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "TACOTINIB ER 11", "category": "ORTHOLOGYRANG", "tags": [ "tofacitinib 11 mg", "tofacitinib 11 mg tablet", "tofacitinib 11 mg price", "tab tofacitinib 11 mg", "tofacitinib 11 mg uses", "Tofacitinib 11 mg extended release tablets", "Tofacitinib 11 mg ER for psoriatic arthritis treatment", "Tofacitinib 11 mg tablet uses and benefits", "Tofacitinib 11 mg ER dosage guide", "Tofacitinib 11 mg side effects and precautions", "Tofacitinib 11 mg daily autoimmune treatment" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6634cc9d4194481fc81fe331", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Cyclosporine 100mg", "description": "CYCLOPURE 100 \nCyclosporine 100 mg\nCYCLOPURE 100™ is a high-strength oral immunosuppressive formulation containing cyclosporine 100 mg, developed to provide reliable and consistent immune system modulation for patients requiring intensive therapy. As a calcineurin inhibitor, cyclosporine plays a vital role in transplant medicine and in the treatment of severe autoimmune and inflammatory disorders.\n\nCYCLOPURE 100™ is designed for patients who require higher dosing as part of their therapeutic regimen. The 100 mg capsule strength supports simplified dosing schedules and improved treatment adherence, particularly in organ transplant recipients and individuals with moderate to severe immune-mediated conditions.\n\nManufactured under strict pharmaceutical quality standards, CYCLOPURE 100™ ensures dose precision, stability, and safety when used under medical supervision.\n\nMechanism of Action\n\nCyclosporine works by selectively inhibiting calcineurin, an intracellular enzyme necessary for activating T-lymphocytes. T-cells are critical mediators of immune responses, particularly in organ rejection and autoimmune inflammation.\n\nBy blocking calcineurin:\n\nT-cell activation is reduced\n\nProduction of pro-inflammatory cytokines decreases\n\nImmune-mediated tissue damage is minimized\n\nRisk of transplant rejection is lowered\n\nThis targeted suppression allows CYCLOPURE 100™ to control immune overactivity while preserving other immune functions, making it highly effective for long-term immune regulation.\n\nIndications and Therapeutic Uses\n\nCYCLOPURE 100™ is prescribed for a variety of medical conditions where immune suppression is necessary.\n\n1. Organ Transplantation\n\nCYCLOPURE 100™ is widely used in:\n\nKidney transplantation\n\nLiver transplantation\n\nHeart transplantation\n\nIts primary role is to prevent the immune system from attacking the transplanted organ, thereby improving graft survival and long-term transplant success.\n\n2. Autoimmune Disorders\n\nCyclosporine is also effective in treating immune-related conditions such as:\n\nRheumatoid arthritis\n\nSevere psoriasis\n\nAtopic dermatitis\n\nNephrotic syndrome\n\nIn these disorders, the immune system mistakenly attacks healthy tissues. CYCLOPURE 100™ helps reduce inflammation, pain, and tissue damage.\n\n3. Other Severe Inflammatory Conditions\n\nUnder specialist supervision, CYCLOPURE 100™ may be used for additional immune-mediated conditions that do not respond adequately to conventional therapies.\n\nKey Benefits of CYCLOPURE 100™\n1. Strong Immunosuppressive Action\n\nThe 100 mg strength provides effective immune suppression for patients requiring higher therapeutic doses, especially in transplant settings.\n\n2. Improved Organ Survival\n\nIn transplant recipients, CYCLOPURE 100™ significantly reduces the risk of acute and chronic organ rejection, enhancing long-term graft function.\n\n3. Symptom Relief in Autoimmune Diseases\n\nPatients may experience:\n\nReduced joint inflammation and stiffness\n\nDecreased skin lesions and redness\n\nImproved kidney function in nephrotic syndrome\n\nReduced flare-ups of inflammatory conditions\n\n4. Flexible Dosing Options\n\nThe 100 mg capsule allows physicians to create individualized treatment plans, often in combination with lower strengths such as 25 mg capsules to achieve precise dosing.\n\n5. Established Clinical Use\n\nCyclosporine has decades of clinical experience worldwide, making it a well-understood and trusted medication in immune therapy.\n\n6. Enhanced Quality of Life\n\nBy stabilizing immune activity, CYCLOPURE 100™ helps patients regain functional independence, reduce hospitalizations, and maintain overall health stability.\n\nDosage and Administration\n\nCYCLOPURE 100™ should be taken strictly according to a physician’s prescription. Dosage varies based on:\n\nBody weight\n\nType of transplant or condition\n\nBlood cyclosporine levels\n\nKidney and liver function\n\nConcurrent medications\n\nAdministration Guidelines\n\nTake capsules at the same time each day.\n\nSwallow whole with water.\n\nDo not crush or chew the capsule.\n\nMaintain consistency with food intake (always with food or always without).\n\nRegular blood tests are essential to monitor cyclosporine levels and adjust dosage as needed. Therapeutic drug monitoring ensures optimal efficacy while minimizing toxicity.\n\nPossible Side Effects\n\nBecause CYCLOPURE 100™ suppresses immune function, side effects may occur, particularly at higher doses.\n\nCommon Side Effects\n\nHigh blood pressure (hypertension)\n\nHeadache\n\nTremors\n\nGum overgrowth\n\nIncreased hair growth\n\nNausea or abdominal discomfort\n\nThese effects are often dose-related and may improve with dosage adjustments.\n\nKidney-Related Effects\n\nCyclosporine can affect kidney function, particularly at higher doses. Monitoring kidney parameters is essential.\n\nWarning signs include:\n\nSwelling in extremities\n\nDecreased urine output\n\nElevated creatinine levels\n\nIncreased Infection Risk\n\nSince the immune system is suppressed, patients may be more susceptible to infections.\n\nSymptoms to monitor:\n\nFever\n\nPersistent cough\n\nSore throat\n\nUnusual fatigue\n\nLiver Function Changes\n\nElevated liver enzymes may occur and require monitoring.\n\nElectrolyte Imbalance\n\nCyclosporine may increase potassium levels and alter magnesium levels.\n\nLong-Term Risks\n\nWith prolonged use, there is a potential increased risk of:\n\nCertain malignancies (particularly skin cancers)\n\nLymphoproliferative disorders\n\nThese risks are carefully managed through medical supervision and routine screening.\n\nPrecautions and Warnings\n\nBefore starting CYCLOPURE 100™, patients should inform their healthcare provider if they have:\n\nPre-existing kidney or liver disease\n\nUncontrolled hypertension\n\nHistory of malignancy\n\nActive infections\n\nPregnancy or breastfeeding plans\n\nDrug Interactions\n\nCyclosporine interacts with numerous medications, including:\n\nCertain antibiotics and antifungals\n\nCalcium channel blockers\n\nAntiepileptic drugs\n\nOther immunosuppressants\n\nHerbal supplements such as St. John’s Wort\n\nPatients must disclose all medications and supplements to their healthcare provider.\n\nVaccination Advisory\n\nLive vaccines are generally contraindicated during cyclosporine therapy due to reduced immune response.\n\nLifestyle Recommendations\n\nTo support safe treatment with CYCLOPURE 100™:\n\nMonitor blood pressure regularly\n\nAttend scheduled laboratory testing appointments\n\nMaintain excellent oral hygiene\n\nLimit sun exposure and use sunscreen\n\nPractice infection prevention measures\n\nFollow dietary guidance, especially regarding potassium intake\n\nClose collaboration with healthcare providers ensures safe and effective long-term therapy.\n\nStorage Instructions\n\nStore at room temperature\n\nKeep away from moisture and heat\n\nProtect from direct sunlight\n\nKeep out of reach of children\n\nDo not use expired medication.\n\nWho Should Use CYCLOPURE 100™?\n\nCYCLOPURE 100™ is suitable for:\n\nOrgan transplant recipients requiring stable immune suppression\n\nPatients with moderate to severe autoimmune conditions\n\nIndividuals who require higher-dose cyclosporine therapy under specialist supervision\n\nIt should always be prescribed and monitored by a qualified healthcare professional.\n\nConclusion\n\nCYCLOPURE 100™ (Cyclosporine 100 mg) is a potent and clinically established immunosuppressive therapy designed to prevent organ rejection and manage serious autoimmune disorders. Its targeted inhibition of T-cell activation provides effective immune modulation, making it a cornerstone medication in transplant medicine and advanced inflammatory disease management.\n\n", "price": 1274.0, "discountamount": 383.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "heat", "body", "risk", "100mg", "signs", "cases", "nausea", "Storage", "diarrhea", "vomiting", "headache", "moisture", "psoriasis", "treatment", "infections", "Drug Class", "components", "prevention", "medication", "Indications", "Precautions", "supervision", "malignancies", "Cyclosporine", "prescription", "immune system", "Administration", "liver toxicity", "kidney function", "organ rejection", "transplant type", "kidney problems", "hypersensitivity", "room temperature", "autoimmune diseases", "individual response", "Common side effects", "healthcare provider", "high blood pressure", "rheumatoid arthritis", "Serious side effects", "transplant recipients", "immunosuppressant drug", "Cyclopure 100 capsules", "uncontrolled hypertension", "heart transplant patients", "Oral Capsules Composition", "Immunosuppressant Dosage Form", "qualified healthcare professional" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1061, "imageuri": "https://productimages.withfloats.com/actual/6634cca7085b40e38314d711.png", "tileimageuri": "https://productimages.withfloats.com/tile/6634cca7085b40e38314d711.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-05-03T11:38:05.78Z", "updatedon": "2026-03-12T09:26:41.912Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//cyclosporine-100mg/1061", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CYCLOPURE 100", "category": "ORTHOLOGYRANG", "tags": [ "cyclosporine 100 mg capsule dosage for kidney transplant patients", "cyclosporine 100 mg soft gelatin capsule brand comparison", "cyclosporine 100 mg trough level monitoring range", "cyclosporine 100 mg dose adjustment in renal impairment", "what is cyclosporine 100 mg used for", "how to take cyclosporine 100 mg capsules safely", "when to monitor blood levels on cyclosporine 100 mg", "buy cyclosporine 100 mg capsules online", "generic cyclosporine 100 mg cost per capsule" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6634cb0595821c1e2ceadc54", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Cyclosporine 25 mg", "description": "CYCLOPURE 25 \nCyclosporin 25 mg\nCYCLOPURE 25™ is a high-quality oral formulation containing Cyclosporine 25 mg, a potent immunosuppressive medication widely used in transplant medicine and the management of certain autoimmune and inflammatory disorders. Designed for precise dosing and reliable absorption, CYCLOPURE 25™ plays a critical role in preventing organ rejection and controlling overactive immune responses.\n\nCyclosporine belongs to a class of medicines known as calcineurin inhibitors. It works by selectively suppressing specific immune cells that contribute to inflammation and immune-mediated damage. By carefully modulating immune function, CYCLOPURE 25™ helps protect transplanted organs and reduces symptoms associated with autoimmune conditions.\n\nEach capsule of CYCLOPURE 25™ is manufactured under stringent pharmaceutical quality standards to ensure safety, consistency, and therapeutic reliability.\n\nHow CYCLOPURE 25™ Works\n\nCyclosporine exerts its effect by inhibiting calcineurin, an enzyme involved in activating T-lymphocytes (a type of white blood cell). T-cells play a central role in the immune response, especially in organ rejection and autoimmune diseases.\n\nWhen calcineurin is blocked:\n\nActivation of T-cells is reduced\n\nProduction of inflammatory cytokines decreases\n\nImmune system activity becomes controlled\n\nRisk of organ rejection is minimized\n\nAutoimmune inflammation is suppressed\n\nThis targeted mechanism allows CYCLOPURE 25™ to effectively reduce harmful immune responses while maintaining necessary immune function.\n\nIndications and Uses\n\nCYCLOPURE 25™ is commonly prescribed for:\n\n1. Organ Transplantation\n\nKidney transplant\n\nLiver transplant\n\nHeart transplant\n\nIt helps prevent the body from rejecting a transplanted organ by suppressing immune reactions against the new tissue.\n\n2. Autoimmune Disorders\n\nRheumatoid arthritis\n\nPsoriasis\n\nSevere atopic dermatitis\n\nCertain forms of nephrotic syndrome\n\nIn these conditions, the immune system mistakenly attacks healthy tissues. CYCLOPURE 25™ helps reduce inflammation and tissue damage.\n\n3. Other Immune-Mediated Conditions\n\nIt may also be prescribed for selected inflammatory or immune-related disorders as determined by a healthcare professional.\n\nKey Benefits of CYCLOPURE 25™\n1. Effective Prevention of Organ Rejection\n\nCYCLOPURE 25™ is a cornerstone medication in transplant medicine, significantly improving long-term graft survival rates.\n\n2. Targeted Immune Suppression\n\nUnlike broad-spectrum immunosuppressants, cyclosporine specifically targets T-cell activation, offering focused immune modulation.\n\n3. Reduction in Autoimmune Symptoms\n\nPatients with rheumatoid arthritis, psoriasis, or severe dermatitis may experience:\n\nReduced joint pain and swelling\n\nDecreased skin lesions and inflammation\n\nImproved mobility and comfort\n\n4. Proven Clinical Track Record\n\nCyclosporine has been used for decades worldwide and remains a trusted therapy in transplant and autoimmune care.\n\n5. Precise 25 mg Dosing\n\nThe 25 mg capsule strength allows physicians to tailor treatment regimens based on individual patient needs and therapeutic drug monitoring.\n\n6. Improved Quality of Life\n\nBy controlling immune overactivity, CYCLOPURE 25™ helps patients maintain better organ function and symptom control, leading to improved daily functioning.\n\nDosage and Administration\n\nCYCLOPURE 25™ should always be taken exactly as prescribed by a healthcare provider. Dosage varies depending on:\n\nThe medical condition being treated\n\nBody weight\n\nBlood cyclosporine levels\n\nKidney function\n\nOther concurrent medications\n\nGeneral guidelines:\n\nTake capsules at the same time each day.\n\nSwallow whole with water.\n\nDo not crush or chew.\n\nMaintain consistency with regard to meals (either always with food or always without).\n\nTherapeutic drug monitoring is often required to measure blood cyclosporine levels and adjust dosage accordingly. Regular laboratory tests are essential during treatment.\n\nPossible Side Effects\n\nBecause CYCLOPURE 25™ affects the immune system, side effects may occur. Some are mild, while others require medical supervision.\n\nCommon Side Effects\n\nIncreased blood pressure\n\nHeadache\n\nTremors (especially in hands)\n\nIncreased hair growth (hypertrichosis)\n\nGum overgrowth\n\nNausea or stomach discomfort\n\nThese side effects may vary in intensity and often depend on dosage.\n\nKidney-Related Effects\n\nCyclosporine can affect kidney function. Monitoring kidney parameters is essential during therapy. Signs of kidney-related issues include:\n\nDecreased urine output\n\nSwelling in legs or ankles\n\nElevated creatinine levels\n\nIncreased Risk of Infections\n\nSince CYCLOPURE 25™ suppresses immune function, patients may become more susceptible to infections.\n\nSymptoms to watch for:\n\nFever\n\nPersistent sore throat\n\nUnusual fatigue\n\nSigns of localized infection\n\nOther Potential Serious Effects\n\nLiver dysfunction\n\nElevated potassium levels\n\nIncreased risk of certain malignancies (especially with long-term use)\n\nNeurological symptoms in rare cases\n\nPatients should immediately report unusual symptoms to their healthcare provider.\n\nPrecautions and Warnings\n\nBefore starting CYCLOPURE 25™, inform your healthcare provider if you:\n\nHave kidney disease\n\nHave liver disease\n\nHave uncontrolled high blood pressure\n\nHave a history of cancer\n\nAre pregnant or breastfeeding\n\nAre taking other immunosuppressants\n\nDrug Interactions\n\nCyclosporine interacts with many medications, including:\n\nCertain antibiotics\n\nAntifungal medications\n\nCalcium channel blockers\n\nAnti-seizure medications\n\nHerbal supplements such as St. John’s Wort\n\nAlways inform your physician about all medications and supplements you are taking.\n\nVaccination Precaution\n\nLive vaccines should generally be avoided while taking CYCLOPURE 25™, as immune suppression may increase risk of infection.\n\nLifestyle Considerations\n\nTo optimize therapy with CYCLOPURE 25™:\n\nMonitor blood pressure regularly\n\nFollow recommended laboratory testing schedules\n\nMaintain proper oral hygiene to prevent gum overgrowth\n\nAvoid excessive sun exposure due to increased skin cancer risk\n\nPractice infection prevention measures\n\nA balanced diet and consistent medical follow-up significantly enhance treatment safety and effectiveness.\n\nStorage Instructions\n\nStore at room temperature\n\nProtect from moisture and direct sunlight\n\nKeep out of reach of children\n\nDo not use beyond the expiration date\n\nWho Should Use CYCLOPURE 25 ™?\n\nCYCLOPURE 25™ is suitable for:\n\nOrgan transplant recipients\n\nPatients with severe autoimmune disorders unresponsive to first-line therapies\n\nIndividuals requiring controlled immune suppression under specialist supervision\nIt should only be used under close medical guidance and regular monitoring.\nConclusion\nCYCLOPURE 25™ (Cyclosporine 25 mg) is a powerful and clinically established immunosuppressive medication designed to protect transplanted organs and manage serious autoimmune conditions. By specifically targeting T-cell activation, it offers precise immune modulation while preserving essential immune functions.\n\n", "price": 342.0, "discountamount": 103.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "body", "risk", "food", "cases", "class", "drugs", "Usage", "heart", "nausea", "doctor", "weight", "kidneys", "vomiting", "diarrhea", "headache", "symptoms", "Benefits", "concerns", "treatment", "psoriasis", "infections", "medication", "supplements", "Precautions", "drug levels", "Composition", "Interactions", "liver damage", "inflammation", "Cyclosporine", "instructions", "manufacturer", "kidney function", "organ rejection", "herbal products", "immune response", "kidney problems", "25mg dosage form", "active ingredient", "recommended dosage", "Regular monitoring", "high blood pressure", "transplanted organs", "CYCLOPURE 25 tablet", "autoimmune diseases", "regular blood tests", "transplant patients", "Common side effects", "rheumatoid arthritis", "Serious side effects", "calcineurin inhibitors", "healthcare professional", "various medical conditions", "inflammatory bowel disease", "potent immunosuppressive agent" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1059, "imageuri": "https://productimages.withfloats.com/actual/6634cb0f022485c14950902a.png", "tileimageuri": "https://productimages.withfloats.com/tile/6634cb0f022485c14950902a.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-05-03T11:31:17.295Z", "updatedon": "2026-03-12T09:24:57.505Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//cyclosporine-25-mg/1059", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CYCLOPURE 25", "category": "ORTHOLOGYRANG", "tags": [ "cyclosporine 25 mg capsule dosage for kidney transplant", "cyclosporine 25 mg twice daily dosing schedule", "cyclosporine 25 mg oral capsule storage instructions", "cyclosporine 25 mg generic vs brand difference", "what is cyclosporine 25 mg used for", "can cyclosporine 25 mg cause high blood pressure", "is cyclosporine 25 mg safe long term", "buy cyclosporine 25 mg capsules online", "cyclosporine 25 mg price per capsule", "cyclosporine 25 mg capsule manufacturer" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "662ba161f7fe09029cbf518e", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Temozolomide 100mg", "description": "TMOZOLMIDE 100\nTemodal 100mg Capsule stands as a cornerstone in oncology, specifically formulated with temozolomide 100mg to combat aggressive brain tumors like glioblastoma multiforme (GBM) and anaplastic astrocytoma. This oral alkylating agent crosses the blood-brain barrier effectively, delivering targeted chemotherapy that disrupts cancer cell DNA replication, halting tumor progression in adults with newly diagnosed or recurrent cases. Patients and caregivers often seek Temodal 100mg for its role in standard-of-care regimens, combining seamlessly with radiotherapy for enhanced survival outcomes in high-grade gliomas.​\n\nManufactured to rigorous standards, Temodal 100mg offers convenient capsule dosing, swallowed whole on an empty stomach to maximize bioavailability. Its proven track record in clinical settings makes it indispensable for neuro-oncology, where timely intervention can extend quality life years amid challenging diagnoses.​\n\nProduct Uses and Mechanism of Action\nTemodal 100mg Capsule primarily treats adult patients with newly diagnosed glioblastoma multiforme alongside radiotherapy, followed by maintenance monotherapy to prevent relapse. It also addresses refractory anaplastic astrocytoma—tumors that progress despite prior therapies—and recurrent malignant gliomas in children over three years, including brainstem glioma and high-grade astrocytoma.​\n\nThe mechanism hinges on temozolomide's rapid conversion to the active metabolite MTIC (5-(3-methyltriazen-1-yl)imidazole-4-carboxamide) at physiological pH, which methylates DNA at O6 and N7 guanine positions. This methylation induces DNA strand breaks during replication, triggering apoptosis in rapidly dividing glioma cells while sparing normal brain tissue to a degree. Unlike intravenous chemotherapies, Temodal 100mg achieves therapeutic CNS concentrations without specialized delivery, ideal for outpatient management.​\n\nIn practice, concomitant phase dosing (75 mg/m² daily with RT for 42 days) transitions to cycles of 150-200 mg/m² on days 1-5 every 28 days, tailored by body surface area and toxicity monitoring. This cyclical approach balances efficacy against cumulative myelosuppression, supporting long-term tumor control.​\n\nKey Benefits of Temodal 100mg Capsule\nTemodal 100mg delivers transformative benefits grounded in landmark trials:\n\nSuperior Survival in GBM: Concomitant temozolomide with RT extends median survival from 12.1 to 14.6 months, with 2-year survival rising from 10% to 26% per pivotal Phase III data.​\n\nMaintenance Therapy Efficacy: Post-RT cycles sustain progression-free survival up to 6-12 months in responders, delaying recurrence in MGMT-methylated tumors.​\n\nConvenient Oral Administration: Eliminates hospital visits, improving compliance for patients undergoing radiotherapy; rapid absorption (peak in 1 hour) ensures consistent exposure.​\n\nBlood-Brain Barrier Penetration: Achieves 30-40% cerebrospinal fluid levels, outperforming many alkylators in CNS malignancies.​\n\nPediatric Applicability: Effective in recurrent pediatric gliomas, with tolerance mirroring adults for ages 3+.​\n\nThese advantages position Temodal 100mg as a first-line essential, particularly for newly diagnosed cases where every month counts toward preserving cognitive function and independence.​\n\nReal-world use extends to off-label scenarios like metastatic melanoma or high-risk meningiomas under specialist oversight, though primary indications remain brain tumors. Its stability in acidic environments enhances reliability during storage and transit.​\n\nSide Effects of Temodal 100mg Capsule\nWhile Temodal 100mg offers life-prolonging potential, its myelotoxic profile demands vigilant hematologic monitoring. Common effects stem from DNA damage in rapidly proliferating bone marrow cells, peaking mid-cycle.​\n\nCommon Side Effects\nHematologic Toxicity: Neutropenia, thrombocytopenia (platelet nadir day 21-28), lymphopenia, and anemia affect 10-20%; febrile neutropenia occurs in vulnerable patients.​\n\nGastrointestinal Issues: Nausea (up to 50%), vomiting, constipation—mitigated by antiemetics like ondansetron taken 30 minutes prior.​\n\nNeurologic Symptoms: Fatigue, headache, ataxia, dizziness, or amnesia-like effects, often transient and RT-attributable.​\n\nOther: Alopecia, anorexia, rash, or elevated liver enzymes resolving post-cycle.​\n\nProphylactic measures like dose delays (if platelets <100 x 10⁹/L or neutrophils <1.5 x 10⁹/L) maintain tolerability; supportive care ensures most complete therapy.​\n\nSerious Side Effects\nRare but critical risks include:\n\nPancytopenia or Aplastic Anemia: Prolonged suppression risking infections or bleeding—mandatory weekly CBCs in early cycles.​\n\nSecondary Malignancies: Myeloid leukemia post-treatment (latency 1-5 years), hepatitis B reactivation.​\n\nOpportunistic Infections: Pneumocystis jirovecii pneumonia (PJP) prophylaxis with TMP-SMX recommended due to grade 3/4 lymphopenia.​\n\nNeurologic Deterioration: Status epilepticus, hemiplegia in advanced disease.​\n\nDiscontinue if non-hematologic CTC grade >2 persists; pregnant women face fetal toxicity—use contraception during and 6 months post-therapy.​\n\nDosage and Administration Guidelines\nInitiate Temodal 100mg at 75 mg/m² daily during RT (up to 49 days), escalating to 150 mg/m² (cycle 1) or 200 mg/m² (subsequent) for 5 days/23 off. Adjust downward for toxicity; hepatic/renal impairment rarely necessitates change unless severe. Capsules (5,20,100,250mg strengths) enable precise BSA-based dosing—e.g., ~100mg capsule for 70kg/m² patients.​\n\nPrecautions and Substitutes\nMonitor pregnancy status; avoid live vaccines. Substitutes include generic temozolomide capsules matching bioequivalence, though Temodal 100mg remains the reference standard. Interactions with valproic acid reduce clearance—increase dose 40% if co-administered.​\n\nConclusion\nTemodal 100mg Capsule empowers patients against glioblastoma's relentless advance, blending potent antineoplastic action with manageable administration for meaningful survival gains. From halting tumor growth via strategic DNA alkylation to fitting seamlessly into multimodal care, it embodies hope amid adversity—always under oncologist guidance to navigate toxicities and optimize outcomes. Embrace informed treatment; lives extend beyond statistics with vigilant care.\nFor further information:\nEmail: info@sterispharma.com / contact@sterispharma.com\nCall/WhatsApp: 7877551268, 7849827488\nBuy Now: \n", "price": 7400.0, "discountamount": 2220.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "part", "body", "types", "drugs", "class", "nausea", "spread", "growth", "surgery", "fatigue", "vomiting", "capsules", "TMOZOLMIDE", "instructions", "Temozolomide", "cancer cells", "brain tumors", "glioblastoma", "unusual symptoms", "potent medication", "other medications", "radiation therapy", "blood cell counts", "healthcare provider", "Common side effects", "comprehensive treatment plan" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 773, "imageuri": "https://productimages.withfloats.com/actual/662ba164481840e7a7fdadc0.png", "tileimageuri": "https://productimages.withfloats.com/tile/662ba164481840e7a7fdadc0.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-04-26T12:43:13.957Z", "updatedon": "2026-03-12T08:07:02.773Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//temozolomide-100mg/773", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "TMOZOLMIDE 100", "category": "NEPHROLOGYRANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6a7722af7f45a0190eb37920", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Tolperisone Hydrochloride & Paracetamol Tablets", "description": "TOPERITIME P 150/325: Dual-Action Relief for Musculoskeletal Pain and Spasms\nTOPERITIME P 150/325 is a prescription combination therapy formulated to treat acute musculoskeletal discomfort, muscle stiffness, and associated inflammatory pain. By uniting a centrally acting muscle relaxant with a proven analgesic, this film-coated tablet addresses both the neurological and physical aspects of muscle strain, restoring movement and facilitating recovery.\n\nActive Ingredients\nEach film-coated tablet contains:\n\nTolperisone Hydrochloride (150 mg): A muscle relaxant targeting involuntary contractions within the central nervous system.\n\nParacetamol (325 mg): A widely recognized analgesic and antipyretic agent that blocks pain signal transmission.\n\nAvailable in blister packaging and dispensed strictly under a licensed physician's order.\n\nTherapeutic Mechanism\nPainful muscle conditions often create a feedback loop where localized pain triggers involuntary spasms, which in turn exacerbate the pain. TOPERITIME P 150/325 disrupts this cycle through a two-pronged mechanism:\n\nNeuromuscular Regulation: Tolperisone Hydrochloride acts on the spinal cord and brainstem reflexes to inhibit hyperactive nerve impulses driving muscle tension. Unlike traditional skeletal muscle relaxants, it achieves this with minimal central nervous system depression, significantly reducing the likelihood of heavy sedation.\n\nNociceptive Blocking: Paracetamol inhibits prostaglandin synthesis within the central nervous system, raising the body's overall pain threshold and attenuating pain signals originating from injured tissues.\n\nBy simultaneously relaxing tight muscle fibers and dampening pain sensation, the formulation provides comprehensive symptomatic relief.\n\nClinical Indications\nHealthcare professionals may prescribe TOPERITIME P 150/325 for various acute and subacute conditions characterized by pain and hypertonia, including:\n\nAcute muscle spasms and athletic injuries\n\nAcute or chronic lower back pain (lumbago)\n\nCervical spine discomfort and stiff neck\n\nCervical and lumbar spondylosis\n\nFrozen shoulder (adhesive capsulitis)\n\nPost-operative or post-traumatic muscle recovery\n\nGeneralized connective tissue or orthopedic pain\n\nKey Clinical Features\nBalanced Dual Action: Simultaneously targets involuntary contractions and pain sensation.\n\nLow-Sedation Profile: Tolperisone allows patients to maintain daily function without severe daytime drowsiness typical of older relaxants.\n\nEnhanced Mobility: Reduces joint and tissue stiffness, enabling better engagement in physical rehabilitation.\n\nStreamlined Regimen: Combines two therapeutic agents into a single convenient dosage form.\n\nUsage Guidelines\nThis medication must be taken strictly in accordance with a medical prescription.\n\nAdministration: Swallow the tablet whole with water. Do not crush, chew, or split the film-coated tablet.\n\nTiming: Take immediately after a meal to reduce potential gastrointestinal upset, unless directed otherwise by a doctor.\n\nCompliance: Complete the full course prescribed by your physician, and do not alter the recommended dosage.\n\nPotential Side Effects\nWhile generally well-tolerated, some individuals may experience mild side effects, including:\n\nGastrointestinal distress or mild nausea\n\nTransient dizziness or lightheadedness\n\nHeadaches\n\nGeneral fatigue or muscular weakness\n\nRare: Hypersensitivity reactions or cutaneous skin rashes (discontinue use and consult a physician immediately if severe symptoms appear).\n\nSafety Precautions and Considerations\nConsult a medical practitioner prior to initiating treatment if any of the following apply:\n\nPre-existing hepatic (liver) or renal (kidney) impairment\n\nKnown hypersensitivity to Tolperisone, Paracetamol, or related compounds\n\nPregnancy, plans for pregnancy, or active breastfeeding\n\nHistory of chronic alcohol dependency (due to increased liver sensitivity with Paracetamol)\n\nConcurrent use of other medications, particularly other products containing Paracetamol or central nervous system depressants\n\nStorage and Handling\nStore in a cool, dry area below 25°C (77°F).\n\nProtect from direct light, heat, and moisture.\n\nKeep strictly out of reach of children and pets.\n\nCheck the packaging expiration date before administration.\n\nFrequently Asked Questions\nWhat primary conditions does TOPERITIME P 150/325 treat?\n\nIt is indicated for short-term relief from acute musculoskeletal pain, muscle spasms, neck strains, backaches, and related orthopedic disorders.\n\nWhy is Tolperisone combined with Paracetamol?\n\nTolperisone eases muscle tightness at the neurological level, while Paracetamol lowers overall pain perception, creating a synergistic effect that addresses both spasm and pain together.\n\nWill this medication cause severe drowsiness?\n\nTolperisone is specifically designed to exert less sedating activity compared to older muscle relaxants. However, individual sensitivity varies, so caution is advised when driving or operating machinery until individual tolerance is established.\n\nIs TOPERITIME P 150/325 available over the counter?\n\nNo. It requires a valid medical prescription and direct supervision by a registered healthcare professional.", "price": 95.0, "discountamount": 29.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2493, "imageuri": "https://productimages.withfloats.com/actual/6a7722b0ed25653efa18364e.png", "tileimageuri": "https://productimages.withfloats.com/tile/6a7722b0ed25653efa18364e.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-08-08T12:35:59.075Z", "updatedon": "2026-08-08T12:35:59.075Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//tolperisone-hydrochloride-paracetamol-tablets/2493", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "TOPERITIME P 150/325", "category": "ORTHOLOGYRANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false } ], "hasmoreitems": false, "isapirequest": false, "totalresults": 27, "query": null, "floatingpoint": null }