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"description": "BENIPRIME 4, containing Benidipine 4 mg, offers effective management for high blood pressure and related heart conditions. This calcium channel blocker helps relax blood vessels to improve blood flow and reduce strain on the heart. Patients often find it reliable for daily control of hypertension symptoms.\n\nWhat is BENIPRIME 4?\nBENIPRIME 4 is a branded tablet from Steris Healthcare Pvt Ltd, featuring 4 mg of Benidipine as the active ingredient. Benidipine belongs to the dihydropyridine class of calcium channel blockers, designed specifically for cardiovascular health. Each tablet delivers a precise dose in a user-friendly form, typically packaged in strips of 10 for convenient use. Manufactured under strict quality standards, it targets essential needs in hypertension care, making it a staple in many treatment plans across India.\n\n\nThis medication stands out due to its triple action on L-type, N-type, and T-type calcium channels, providing broader vascular protection compared to some other blockers. Doctors prescribe it for adults dealing with persistent high blood pressure or chest pain, often starting at this 4 mg strength for balanced efficacy. Unlike generic options, BENIPRIME 4 ensures consistent absorption and formulation tailored for Indian patients, with pricing around Rs 62-89 per strip after discounts.\n\n\nHow BENIPRIME 4 Works\nBenidipine in BENIPRIME 4 blocks calcium entry into smooth muscle cells of blood vessels and heart muscles. This action causes vasodilation, widening arteries to lower resistance and ease blood flow. By reducing systolic and diastolic pressure, it lightens the heart's workload without drastically slowing the heartbeat.\n\n\nThe unique blockade of multiple calcium channels also boosts nitric oxide production, offering antioxidant effects and protection against artery hardening. This sustained mechanism provides 24-hour control, ideal for once-daily dosing after breakfast. Over time, it may even reduce urinary protein and triglycerides, supporting kidney and metabolic health in hypertensives.\n\n\nKey Uses of BENIPRIME 4\nBENIPRIME 4 primarily treats essential hypertension, helping prevent strokes, heart attacks, and kidney damage. It effectively manages angina pectoris by enhancing coronary blood supply, reducing chest pain episodes during activity.\n\n\nPhysicians also use it for renal parenchymal hypertension, where kidney issues elevate blood pressure. In emergencies like hypertensive crises or subarachnoid hemorrhage, higher doses prove beneficial, though 4mg serves as maintenance. For arrhythmia or anal fissures linked to vascular strain, it offers supportive relief.\n\n\nLowers high blood pressure in adults, including severe cases with dose adjustments.\n\n\nEases angina symptoms, improving exercise tolerance and daily life quality.\n\n\nProtects renal function in proteinuric patients by stabilizing vessels.\n\n\nDosage and Administration\nTake BENIPRIME 4 as 4 mg once daily, swallowed whole after a meal to minimize stomach upset. Doctors may adjust to 2-8mg based on response, age, or kidney/liver status, never exceeding 8 mg daily without monitoring. Consistency in timing ensures steady levels for optimal pressure control.\n\n\nMissed doses require prompt intake if remembered soon, but skip if near the next one—avoid doubles. Pair with lifestyle changes like low-salt diets and exercise for best results. Always consult for personalization, especially in elderly or comorbid patients.\n\n\nKey Benefits\nBENIPRIME 4 excels in long-term blood pressure reduction, with studies showing sustained drops in brachial-ankle pulse wave velocity beyond mere pressure effects. It protects the heart and kidneys through anti-sclerotic and antioxidant actions, lowering cardiovascular event risks.\n\n\nPatients experience fewer angina attacks, better endurance, and improved quality of life. The once-daily regimen boosts adherence, while vascular selectivity minimizes reflex tachycardia common in other blockers. Clinical data indicate reduced C-reactive protein and aldosterone, curbing inflammation and fibrosis.\n\n\nBenefit\tDescription\tSupporting Evidence\nBP Control\tReduces systolic/diastolic pressure effectively over 24 hours \n\tLong-term studies show persistent effects post-treatment \n\nHeart Protection\tImproves coronary flow, cuts angina frequency \n\tMyocardial protection via NO stimulation \n\nRenal Support\tLowers proteinuria, aids kidney hypertension \n\tAnti-oxidative vascular benefits \n\nAdherence Ease\tOnce-daily dosing with sustained release \n\tHigh membrane affinity for lasting action \n\nAdditional perks include potential triglyceride reduction and osteoblast stimulation for bone health in hypertensives.\n\nPotential Side Effects\nMost users tolerate BENIPRIME 4 well, with mild, transient effects resolving spontaneously. Common issues include headache, dizziness, flushing, ankle swelling, palpitations, fatigue, nausea, and sleepiness.\n\n\nLess frequent are constipation, abdominal pain, tinnitus, shoulder stiffness, urinary frequency, or elevated liver enzymes. Rare serious reactions involve severe hypotension, rash, itching, or allergic responses—seek immediate care if these arise. Monitor blood pressure during initiation to avoid drops.\n\nHeart-related: Palpitations, chest pressure\n\n\nNervous system: Dizziness, headache\n\nSkin/Vascular: Flushing, edema.\n\nGI: Nausea, constipation\n\n\nLiver/kidney patients need caution; inform doctors of history.\n\n\nPrecautions and Interactions\nAvoid in hypotension, severe aortic stenosis, or hypersensitivity to dihydropyridines. Use cautiously in liver/kidney impairment, pregnancy, or breastfeeding—benefits must outweigh risks. Grapefruit juice may amplify effects; limit alcohol.\n\n\nIt interacts with beta-blockers, digoxin, or CYP3A4 inhibitors like ketoconazole, potentially enhancing hypotension. Regular monitoring of BP, electrolytes, and renal function is advised during therapy. Abrupt stop may rebound pressure; taper under guidance.\n\nConclusion\nBENIPRIME 4 with Benidipine 4 mg empowers reliable hypertension and angina control through innovative calcium channel action. Balancing potent benefits like organ protection and ease of use against manageable side effects, it fits seamlessly into modern cardiac care. Consult healthcare providers for tailored integration with lifestyle for lasting heart health. ",
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"name": "Trazodone Hydrochloride 50 mg",
"description": "TORRANE 50 is a pharmaceutical formulation containing Trazodone Hydrochloride 50 mg as its active ingredient. This medication belongs to the class of serotonin antagonist and reuptake inhibitors (SARIs), primarily prescribed for the management of major depressive disorder and associated sleep disturbances. TORRANE 50 represents a trusted therapeutic option that has been helping individuals regain emotional balance and improve their quality of life for decades. The medication works by modulating serotonin levels in the brain, offering relief from depression while simultaneously addressing insomnia that often accompanies mood disorders.\nUnderstanding Trazodone Hydrochloride\nTrazodone Hydrochloride is a unique antidepressant that distinguishes itself from other medications in its class through its dual-action mechanism. Unlike traditional selective serotonin reuptake inhibitors (SSRIs), TORRANE 50 not only helps restore serotonin balance but also possesses sedative properties that make it particularly valuable for patients struggling with both depression and sleep difficulties. The 50mg dosage represents a common starting point for treatment, allowing healthcare providers to carefully titrate the dose according to individual patient needs and responses.\nPrimary Uses and Applications\nTORRANE 50 serves multiple therapeutic purposes, making it a versatile option in psychiatric and general medical practice. The primary indication for this medication is major depressive disorder, where it helps alleviate symptoms such as persistent sadness, loss of interest in daily activities, feelings of worthlessness, and difficulty concentrating. Beyond its antidepressant properties, TORRANE 50 has gained significant recognition for its effectiveness in treating insomnia, particularly when sleep disturbances are related to depression or anxiety.\nHealthcare providers may also prescribe TORRANE 50 off-label for various conditions including generalized anxiety disorder, panic disorder, and chronic pain conditions where sleep disturbance is a prominent feature. The medication's ability to improve sleep architecture without the dependency risks associated with traditional benzodiazepines makes it an attractive option for long-term management of sleep-related issues.\nKey Benefits and Therapeutic Advantages\nThe benefits of TORRANE 50 extend far beyond simple symptom management, offering patients a comprehensive approach to mental health wellness. One of the most significant advantages is its dual-action profile, addressing both mood and sleep disturbances simultaneously. This is particularly beneficial because depression and insomnia often exist in a cyclical relationship, where each condition exacerbates the other.\nTORRANE 50 demonstrates a relatively favorable side effect profile compared to some other antidepressants, with lower risks of sexual dysfunction, which is a common concern with many SSRI medications. This makes it an excellent alternative for patients who have experienced these troublesome side effects with other antidepressants. Additionally, the medication is not associated with significant weight gain in most patients, addressing another common concern that can affect medication adherence.\nThe sedative properties of TORRANE 50, while beneficial for sleep, are dose-dependent, allowing physicians to customize treatment strategies. At lower doses, the medication primarily promotes sleep, while higher doses deliver more pronounced antidepressant effects. This flexibility enables healthcare providers to tailor treatment to individual patient needs effectively.\nAnother notable benefit is that TORRANE 50 has a relatively low potential for abuse compared to benzodiazepines and other sleep medications, making it safer for long-term use in appropriate patients. The medication also begins to improve sleep quality relatively quickly, often within the first week of treatment, though the full antidepressant effects may take several weeks to manifest fully.\nPotential Side Effects and Considerations\nLike all medications, TORRANE 50 may cause side effects, though not everyone experiences them. Understanding these potential effects helps patients and healthcare providers work together to optimize treatment outcomes. Common side effects include drowsiness and dizziness, particularly when starting the medication or increasing the dose. These effects are often most pronounced in the first few days of treatment and typically diminish as the body adjusts to the medication.\nSome patients may experience dry mouth, blurred vision, constipation, or headaches. These anticholinergic effects are generally mild and manageable. Nausea and gastrointestinal discomfort can occur, particularly if the medication is taken on an empty stomach. Taking TORRANE 50 with food can help minimize these digestive concerns.\nMore serious but less common side effects include orthostatic hypotension, which is a sudden drop in blood pressure upon standing that can lead to dizziness or fainting. Patients, especially older adults, should be cautioned to rise slowly from sitting or lying positions. In rare cases, TORRANE 50 may cause priapism, a prolonged and painful erection requiring immediate medical attention.\nCardiac considerations include potential changes in heart rhythm, and patients with pre-existing heart conditions should be monitored carefully. Some individuals may experience changes in alertness or cognitive function, which can affect the ability to drive or operate machinery safely, particularly when first starting treatment.\nAs with many antidepressants, there is a theoretical risk of increased suicidal thoughts, particularly in young adults and adolescents during the initial weeks of treatment. Close monitoring during this period is essential, and patients should immediately report any worsening of depression or emergence of suicidal thoughts.\nImportant Safety Information\nPatients should inform their healthcare provider about all medications, supplements, and herbal products they are taking, as TORRANE 50 can interact with numerous substances. Particularly significant interactions occur with monoamine oxidase inhibitors (MAOIs), other antidepressants, blood thinners, and medications affecting the central nervous system. Alcohol should be avoided during treatment as it can intensify sedation and increase the risk of adverse effects.\nTORRANE 50 should not be stopped abruptly without medical supervision, as discontinuation syndrome can occur, causing symptoms such as anxiety, agitation, and sleep disturbances. Healthcare providers will typically recommend gradual dose reduction when discontinuing the medication.\nConclusion\nTORRANE 50 (Trazodone Hydrochloride 50 mg) represents a valuable therapeutic option for individuals struggling with depression and sleep disturbances. Its unique dual-action mechanism, addressing both mood regulation and sleep quality, sets it apart in the landscape of psychiatric medications. The favorable side effect profile, particularly regarding sexual function and weight concerns, combined with its low abuse potential, makes TORRANE 50 an attractive choice for both patients and healthcare providers.",
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"description": "TORRANE 100 is a pharmaceutical formulation containing Trazodone Hydrochloride 100 mg as its active ingredient. This prescription medication belongs to the class of serotonin antagonist and reuptake inhibitors (SARIs), primarily designed to address major depressive disorder and associated sleep disturbances. TORRANE 100 represents a therapeutic solution that combines antidepressant properties with sedative effects, making it a versatile option for patients struggling with depression, particularly when accompanied by insomnia or anxiety symptoms.\nThe formulation comes in tablet form, designed for oral administration, and works by modulating serotonin levels in the brain. Unlike many traditional antidepressants, TORRANE 100 offers a unique mechanism of action that sets it apart in the treatment landscape, providing relief not only from depressive symptoms but also addressing sleep-related issues that often accompany mental health conditions.\nHow TORRANE 100 Works\nTORRANE 100 operates through a dual mechanism that influences brain chemistry. The active ingredient, Trazodone Hydrochloride, primarily inhibits the reuptake of serotonin—a neurotransmitter crucial for mood regulation—while simultaneously blocking certain serotonin receptors. This balanced approach helps restore emotional equilibrium and promotes a sense of well-being.\nThe medication's sedative properties stem from its antihistamine effects and alpha-adrenergic blocking activity, which contribute to its effectiveness in treating insomnia. When taken as prescribed, TORRANE 100 typically begins working within one to two weeks for depressive symptoms, though sleep improvements may be noticed sooner, often within the first few days of treatment.\nPrimary Uses and Applications\nTORRANE 100 is indicated for several therapeutic purposes:\nMajor Depressive Disorder: The primary indication for TORRANE 100 is the treatment of depression. Patients experiencing persistent sadness, loss of interest in daily activities, changes in appetite, or feelings of worthlessness may benefit from this medication under proper medical supervision.\nInsomnia Associated with Depression: One of the distinguishing features of TORRANE 100 is its effectiveness in treating sleep disturbances linked to depression. The medication helps patients fall asleep faster and maintain sleep throughout the night without causing the same dependency concerns associated with traditional sleeping pills.\nAnxiety Disorders: Healthcare providers sometimes prescribe TORRANE 100 off-label for anxiety disorders, as the medication's calming properties can help reduce excessive worry and tension.\nChronic Pain Management: In some cases, medical professionals utilize TORRANE 100 as part of a comprehensive pain management strategy, particularly for conditions involving neuropathic pain.\nKey Benefits of TORRANE 100\nThe therapeutic advantages of TORRANE 100 extend beyond simple symptom management:\nDual Action Formula: Unlike medications that target only depression or only sleep, TORRANE 100 addresses both concerns simultaneously, reducing the need for multiple prescriptions and simplifying treatment regimens.\nLower Addiction Potential: Compared to benzodiazepines and other sedative-hypnotics, TORRANE 100 carries a significantly lower risk of dependency, making it a safer long-term option for patients requiring ongoing sleep support.\nImproved Sleep Architecture: The medication promotes natural sleep patterns without severely disrupting REM sleep, which is essential for cognitive function and emotional processing.\nFewer Sexual Side Effects: Unlike many selective serotonin reuptake inhibitors (SSRIs), TORRANE 100 typically causes fewer sexual dysfunction issues, which can improve treatment adherence and quality of life.\nMood Stabilization: Patients often experience gradual improvement in overall mood, reduced irritability, and enhanced emotional resilience as treatment progresses.\nAnxiety Reduction: The anxiolytic properties help diminish racing thoughts and physical tension that often accompany depressive episodes.\nEnhanced Daily Functioning: By improving both mood and sleep quality, TORRANE 100 helps patients regain energy, concentration, and motivation to engage in daily activities and maintain relationships.\nPotential Side Effects\nWhile TORRANE 100 is generally well-tolerated, patients should be aware of possible adverse reactions:\nCommon Side Effects: Drowsiness and dizziness are the most frequently reported effects, particularly when initiating treatment or adjusting dosage. Dry mouth, blurred vision, constipation, and headaches may also occur but typically diminish as the body adjusts to the medication.\nOrthostatic Hypotension: Some patients experience a drop in blood pressure upon standing, leading to lightheadedness. Rising slowly from sitting or lying positions can help minimize this effect.\nGastrointestinal Disturbances: Nausea, vomiting, or changes in appetite may occur, though taking the medication with food often reduces these symptoms.\nWeight Changes: Some individuals may experience weight gain or loss during treatment.\nSerious but Rare Side Effects: Though uncommon, patients should seek immediate medical attention if experiencing priapism (prolonged painful erection), irregular heartbeat, severe dizziness, fainting, or signs of serotonin syndrome (confusion, rapid heartbeat, severe muscle stiffness).\nCardiac Considerations: TORRANE 100 may cause changes in heart rhythm, particularly in patients with pre-existing cardiac conditions.\nWithdrawal Symptoms: Abrupt discontinuation may lead to withdrawal effects; therefore, dosage should be tapered gradually under medical supervision.\nImportant Safety Considerations\nPatients should inform their healthcare provider about all medications, supplements, and herbal products they're taking, as TORRANE 100 can interact with numerous substances. Alcohol should be avoided, as it can intensify sedative effects. The medication may impair judgment and coordination, so caution is advised when driving or operating machinery until individual response is established.\nPregnant women, nursing mothers, and individuals with certain medical conditions should discuss the risks and benefits with their healthcare provider before starting TORRANE 100. Regular monitoring and follow-up appointments are essential to ensure optimal therapeutic outcomes and promptly address any concerns.\nConclusion\nTORRANE 100 represents a valuable therapeutic option for individuals battling depression, particularly when complicated by sleep disturbances. Its unique pharmacological profile offers comprehensive relief by addressing multiple symptoms simultaneously, potentially improving treatment adherence and quality of life. The medication's relatively favorable side effect profile, combined with lower addiction potential compared to traditional sleep aids, makes it an attractive choice for long-term management.",
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"description": "ESMOSTRUM IT: Comprehensive Product Guide\nProduct Overview\nESMOSTRUM IT is an advanced pharmaceutical formulation that combines two potent active ingredients—Esomeprazole and Itopride—to provide comprehensive relief from gastrointestinal disorders. This dual-action medication represents a significant advancement in the management of acid-related digestive conditions and motility disorders. By combining a proton pump inhibitor with a prokinetic agent, ESMOSTRUM IT addresses both the underlying causes and symptomatic manifestations of various digestive ailments, offering patients a complete therapeutic solution in a single, convenient dosage form.\nThe synergistic combination of Esomeprazole and Itopride makes ESMOSTRUM IT particularly effective for individuals suffering from gastroesophageal reflux disease (GERD), functional dyspepsia, and other conditions where both excessive acid production and impaired gastric motility contribute to discomfort and disease progression.\nActive Pharmaceutical Ingredients\nEsomeprazole\nEsomeprazole is the S-isomer of omeprazole and belongs to the class of medications known as proton pump inhibitors (PPIs). It works by specifically and irreversibly blocking the hydrogen-potassium adenosine triphosphatase enzyme system (the proton pump) located in the gastric parietal cells. This mechanism effectively reduces gastric acid secretion, providing sustained relief from acid-related symptoms and allowing damaged esophageal and gastric tissue to heal.\nItopride\nItopride is a prokinetic agent that enhances gastrointestinal motility through a dual mechanism of action. It acts as both a dopamine D2 receptor antagonist and an acetylcholinesterase inhibitor. By blocking dopamine receptors, it removes the inhibitory effect of dopamine on gastrointestinal motility, while its acetylcholinesterase inhibition increases acetylcholine levels, further promoting coordinated gastric contractions and improved gastric emptying.\nTherapeutic Uses and Indications\nESMOSTRUM IT is prescribed for a wide range of gastrointestinal conditions where both acid suppression and enhanced motility are therapeutically beneficial:\nGastroesophageal Reflux Disease (GERD)\nESMOSTRUM IT provides exceptional relief for patients suffering from GERD, a chronic condition where stomach acid frequently flows back into the esophagus. The esomeprazole component reduces acid production, while itopride improves the tone of the lower esophageal sphincter and accelerates gastric emptying, thereby reducing the frequency and severity of reflux episodes.\nFunctional Dyspepsia\nFor patients experiencing persistent or recurrent upper abdominal discomfort without an identifiable organic cause, ESMOSTRUM IT addresses multiple pathophysiological mechanisms. It relieves symptoms such as early satiety, postprandial fullness, epigastric pain, and bloating by normalizing gastric acid levels and improving gastric accommodation and emptying.\nPeptic Ulcer Disease\nESMOSTRUM IT aids in the healing of gastric and duodenal ulcers by creating an optimal healing environment through sustained acid suppression. The prokinetic action of itopride helps prevent stasis of gastric contents, which can exacerbate ulcer symptoms.\nNon-Ulcer Dyspepsia\nMany patients experience dyspeptic symptoms without evidence of ulceration. ESMOSTRUM IT effectively manages these symptoms by addressing both acid hypersecretion and delayed gastric emptying, two key factors in non-ulcer dyspepsia.\nGastroparesis-Related Symptoms\nIn conditions where gastric emptying is significantly delayed, the itopride component of ESMOSTRUM IT helps restore more normal gastric motility patterns, reducing associated symptoms like nausea, vomiting, and abdominal distension.\nKey Benefits and Advantages\nDual Mechanism of Action\nThe primary advantage of ESMOSTRUM IT lies in its comprehensive approach to gastrointestinal health. Rather than addressing only acid production or motility in isolation, this combination therapy tackles both aspects simultaneously, providing more complete symptom relief and better therapeutic outcomes.\nSuperior Acid Suppression\nEsomeprazole offers more consistent and prolonged acid suppression compared to many other acid-reducing medications. It provides sustained relief throughout the day and night, allowing patients to experience fewer breakthrough symptoms and better quality of life.\nEnhanced Gastric Motility\nThe itopride component specifically targets motility issues without crossing the blood-brain barrier significantly, meaning it provides prokinetic benefits with minimal central nervous system side effects. This results in improved gastric emptying, reduced bloating, and decreased feelings of fullness after meals.\nRapid Symptom Relief\nMany patients experience noticeable improvement in their symptoms within the first few days of treatment with ESMOSTRUM IT. The combination therapy addresses multiple symptom pathways simultaneously, leading to faster and more comprehensive relief.\nImproved Quality of Life\nBy effectively managing symptoms such as heartburn, regurgitation, nausea, bloating, and early satiety, ESMOSTRUM IT significantly enhances patients' daily functioning and overall well-being. Patients report better sleep quality, improved dietary tolerance, and reduced anxiety related to their digestive symptoms.\nConvenient Dosing\nThe combination of two active ingredients in a single formulation improves medication adherence by reducing pill burden. Patients appreciate the simplicity of taking one medication instead of multiple separate preparations.\nMucosal Healing Properties\nBeyond symptom relief, ESMOSTRUM IT promotes actual healing of damaged esophageal and gastric mucosa. The reduced acid environment created by esomeprazole allows inflamed and eroded tissue to regenerate properly.\nReduced Risk of Complications\nBy effectively controlling acid reflux and improving gastric emptying, ESMOSTRUM IT helps prevent potential complications of chronic GERD, such as esophageal strictures, Barrett's esophagus, and respiratory complications from aspiration.\nDosage and Administration\nESMOSTRUM IT should be taken exactly as prescribed by a healthcare professional. Typically, the medication is administered orally, preferably before meals to optimize its therapeutic effects. The standard dosing regimen usually involves once or twice daily administration, though individual requirements may vary based on the severity of the condition and patient response.\nThe medication should be swallowed whole with water and should not be crushed, chewed, or split, as this may affect the drug's release mechanism and therapeutic efficacy. Patients should maintain regular dosing schedules to ensure optimal acid suppression and motility enhancement throughout the day.\nSide Effects and Safety Considerations\nLike all medications, ESMOSTRUM IT may cause side effects in some individuals, though not everyone experiences them. Understanding potential adverse effects helps patients identify and report concerning symptoms promptly.\nCommon Side Effects\nGastrointestinal Effects: Some patients may experience diarrhea, constipation, abdominal pain, nausea, or flatulence, particularly during initial treatment. These effects are usually mild and often resolve as the body adjusts to the medication.\nHeadache: Mild to moderate headaches occur in a small percentage of patients and typically diminish with continued use.\nDizziness: Some individuals may experience lightheadedness or dizziness, particularly when standing up quickly.\nDry Mouth: Reduced saliva production may occur, leading to oral dryness and discomfort.\nLess Common Side Effects\nSkin Reactions: Rash, itching, or other dermatological manifestations may develop in sensitive individuals.\nSleep Disturbances: Some patients report insomnia or unusual dreams while taking the medication.\nIncreased Prolactin Levels: Itopride may cause mild elevation in prolactin levels, though clinical manifestations are rare.\nTaste Alterations: Changes in taste perception or metallic taste may occur temporarily.\nSerious Side Effects (Rare)\nWhile uncommon, certain serious adverse effects require immediate medical attention:\n\nSevere allergic reactions including difficulty breathing, facial swelling, or severe skin reactions\nSevere diarrhea that persists or contains blood\nIrregular heartbeat or palpitations\nMuscle weakness or pain\nSeizures or tremors\nSigns of liver problems including jaundice, dark urine, or persistent nausea\n\nLong-Term Considerations\nExtended use of proton pump inhibitors like esomeprazole has been associated with certain risks that patients should discuss with their healthcare providers:\n\nPotential reduction in calcium, magnesium, and vitamin B12 absorption\nSlightly increased risk of bone fractures with prolonged use\nPossible increased susceptibility to certain gastrointestinal infections\nRare cases of kidney problems\n\nRegular monitoring and periodic assessment by healthcare professionals help minimize these risks while maintaining therapeutic benefits.\nPrecautions and Contraindications\nPatients should inform their healthcare provider about all existing medical conditions, particularly liver disease, kidney problems, osteoporosis, low magnesium levels, or any gastrointestinal bleeding. ESMOSTRUM IT may interact with certain medications, including blood thinners, antifungals, HIV medications, and certain antibiotics. A complete medication review ensures safe and effective therapy.\nPregnant or breastfeeding women should only use ESMOSTRUM IT under strict medical supervision, as the safety profile in these populations requires careful consideration of potential risks and benefits.\nLifestyle Recommendations\nFor optimal therapeutic outcomes, patients taking ESMOSTRUM IT should complement their medication regimen with appropriate lifestyle modifications:\n\nAvoid trigger foods that exacerbate acid reflux, such as spicy foods, citrus, chocolate, caffeine, and alcohol\nMaintain a healthy body weight to reduce abdominal pressure\nEat smaller, more frequent meals rather than large portions\nAvoid lying down immediately after eating; wait at least two to three hours\nElevate the head of the bed if nighttime symptoms occur\nQuit smoking, as tobacco use significantly worsens reflux symptoms\nManage stress through relaxation techniques, as stress can exacerbate digestive symptoms\n\nConclusion\nESMOSTRUM IT represents a sophisticated and effective pharmaceutical solution for individuals struggling with complex gastrointestinal disorders involving both acid hypersecretion and impaired motility. By combining the powerful acid-suppressing capabilities of esomeprazole with the prokinetic benefits of itopride, this medication offers comprehensive symptom management that addresses the multifaceted nature of digestive disorders.",
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"description": "CLANARIZINE DOM represents an advanced pharmaceutical combination that brings together two potent therapeutic agents—Cinnarizine and Domperidone—in a single convenient tablet formulation. This innovative combination medication addresses multiple aspects of vestibular disorders, motion sickness, and associated nausea and vomiting, providing comprehensive relief for patients suffering from these debilitating conditions. Manufactured under stringent quality control standards, CLANARIZINE DOM offers a synergistic approach to managing symptoms that significantly impact quality of life and daily functioning.The combination of Cinnarizine and Domperidone in CLANARIZINE DOM is based on sound pharmacological principles. While Cinnarizine works primarily on the vestibular system to reduce dizziness and vertigo, Domperidone acts as an effective antiemetic to control nausea and vomiting. Together, these two active ingredients provide more comprehensive symptom control than either agent alone, making CLANARIZINE DOM an excellent choice for patients experiencing vestibular disturbances accompanied by gastrointestinal symptoms.This combination therapy is particularly valuable because vertigo, dizziness, and motion sickness are frequently accompanied by nausea and vomiting. Patients suffering from these conditions often find that addressing only one aspect of their symptoms provides insufficient relief. CLANARIZINE DOM's dual-action formula tackles both the underlying vestibular dysfunction and the accompanying gastrointestinal distress, offering patients a more complete therapeutic solution that improves both comfort and functional capacity.Understanding the Active IngredientsCinnarizine is a calcium channel blocker with specific antihistaminic and vestibular suppressant properties. Unlike systemic calcium channel blockers used for cardiovascular conditions, Cinnarizine selectively acts on the blood vessels in the inner ear and brain, improving blood flow to these areas. This enhanced circulation helps reduce the frequency and severity of vertigo attacks while also preventing motion sickness. Cinnarizine also possesses mild antihistaminic effects that contribute to its anti-nausea properties, though this is not its primary mechanism of action.The medication works by blocking calcium channels in the vestibular system, which helps stabilize the sensory organs responsible for balance. By reducing the excessive stimulation of the vestibular apparatus, Cinnarizine decreases the sensation of spinning or imbalance that characterizes vertigo. Additionally, its vasodilatory effects improve microcirculation in the inner ear, which can be beneficial for conditions where reduced blood flow contributes to symptoms.Domperidone is a peripheral dopamine antagonist that acts primarily as a prokinetic and antiemetic agent. Unlike some antiemetic medications that cross the blood-brain barrier and cause sedation or extrapyramidal side effects, Domperidone works predominantly in the peripheral nervous system. It blocks dopamine receptors in the chemoreceptor trigger zone (CTZ) located outside the blood-brain barrier, effectively preventing nausea and vomiting without causing significant central nervous system effects.Domperidone also enhances gastrointestinal motility by promoting coordinated contractions of the stomach and upper small intestine. This prokinetic effect helps empty the stomach more efficiently, reducing feelings of fullness, bloating, and discomfort that often accompany vestibular disorders. By accelerating gastric emptying, Domperidone also reduces the likelihood of gastroesophageal reflux, which can exacerbate nausea in some patients.The combination of these two medications in CLANARIZINE DOM creates a complementary therapeutic effect. While Cinnarizine addresses the vestibular component of dizziness and vertigo, Domperidone manages the gastrointestinal symptoms that frequently accompany these conditions. This dual approach provides more comprehensive symptom relief and improves overall treatment outcomes compared to monotherapy with either agent alone.Clinical Applications and UsesCLANARIZINE DOM is indicated for a wide range of conditions characterized by vertigo, dizziness, and associated nausea. Understanding these clinical applications helps healthcare providers select appropriate candidates for this combination therapy.Vestibular Disorders: The primary indication for CLANARIZINE DOM includes various vestibular disorders that cause vertigo and imbalance. These conditions include Ménière's disease, benign paroxysmal positional vertigo (BPPV), vestibular neuritis, and labyrinthitis. Patients with these disorders experience episodes of spinning sensation, loss of balance, and often severe nausea. CLANARIZINE DOM helps reduce the frequency and intensity of vertigo attacks while controlling the accompanying gastrointestinal symptoms.Motion Sickness: CLANARIZINE DOM is highly effective for preventing and treating motion sickness, whether related to travel by car, boat, airplane, or amusement park rides. The medication can be taken prophylactically before travel or at the onset of symptoms. The combination is particularly useful for individuals who experience severe nausea and vomiting with motion sickness, as Domperidone provides powerful antiemetic effects that complement Cinnarizine's anti-motion-sickness properties.Migraine-Associated Vertigo: Many patients with migraines experience vestibular symptoms, including dizziness, vertigo, and motion sensitivity, either during migraine attacks or as independent episodes. CLANARIZINE DOM can help manage these vestibular manifestations of migraine, reducing both the vertigo and the nausea that often accompany migraine headaches.Post-Concussion Syndrome: Following head injuries, some patients develop persistent dizziness, balance problems, and nausea as part of post-concussion syndrome. CLANARIZINE DOM may provide symptomatic relief for these patients during their recovery period, though it should be used as part of a comprehensive treatment approach that includes rest, gradual return to activities, and vestibular rehabilitation when appropriate.Cerebrovascular Insufficiency: In older adults with reduced blood flow to the brain, symptoms such as dizziness, vertigo, tinnitus (ringing in the ears), and cognitive difficulties may develop. Cinnarizine's vasodilatory properties can improve cerebral circulation, potentially reducing these symptoms. The addition of Domperidone helps manage any associated nausea.Radiation-Induced or Chemotherapy-Induced Nausea: While not a primary indication, some healthcare providers use CLANARIZINE DOM as adjunctive therapy for patients undergoing cancer treatment who experience both nausea and dizziness. Domperidone's strong antiemetic properties are particularly valuable in this context.Key Benefits of CLANARIZINE DOMThe unique combination of Cinnarizine and Domperidone in CLANARIZINE DOM offers numerous advantages that make it a preferred choice for managing vestibular disorders and associated symptoms.Comprehensive Symptom Control: The primary benefit of CLANARIZINE DOM is its ability to address multiple symptoms simultaneously. Rather than requiring patients to take separate medications for vertigo and nausea, this combination provides unified treatment in a single tablet. This comprehensive approach improves symptom control across the full spectrum of vestibular disorder manifestations, from the spinning sensation to the gastrointestinal distress that often accompanies it.Improved Patient Compliance: Taking multiple medications can be burdensome, particularly for patients who feel dizzy or nauseated. CLANARIZINE DOM simplifies the treatment regimen by combining two medications in one tablet, making it easier for patients to adhere to their prescribed therapy. Better compliance translates to better outcomes, as consistent medication use is essential for managing chronic vestibular conditions.Synergistic Therapeutic Effects: The combination of Cinnarizine and Domperidone creates synergistic effects that enhance overall efficacy. While Cinnarizine reduces vestibular stimulation and improves inner ear blood flow, Domperidone prevents nausea and promotes gastric emptying. This dual action addresses both the cause and consequences of vestibular dysfunction, providing more complete relief than either medication alone.Reduced Central Nervous System Side Effects: Because Domperidone works primarily in the peripheral nervous system rather than crossing the blood-brain barrier extensively, CLANARIZINE DOM causes less sedation and fewer cognitive effects compared to some alternative antiemetic medications. This allows patients to maintain better alertness and function during treatment, which is particularly important for those who need to continue working or performing daily activities.Enhanced Quality of Life: Vertigo and chronic dizziness significantly impair quality of life, limiting mobility, social interactions, and occupational functioning. The nausea and vomiting that accompany these conditions add another layer of disability. By effectively controlling both vestibular and gastrointestinal symptoms, CLANARIZINE DOM helps restore patients' ability to engage in normal activities, improving overall life satisfaction and functional independence.Fast Onset of Action: CLANARIZINE DOM provides relatively rapid symptom relief, with many patients experiencing improvement within 30 minutes to 2 hours after taking the medication. This quick onset is particularly valuable for acute episodes of vertigo or when taking the medication prophylactically before situations that might trigger motion sickness.Suitable for Long-Term Use: For patients with chronic vestibular disorders requiring ongoing treatment, CLANARIZINE DOM is generally safe for extended use when properly monitored by a healthcare provider. The medication maintains its effectiveness over time without significant tolerance development, making it suitable for long-term symptom management.Improved Gastric Emptying: The prokinetic effects of Domperidone benefit not only nausea but also other gastrointestinal symptoms such as early satiety, bloating, and upper abdominal discomfort. Patients with vestibular disorders often develop gastroparesis or delayed gastric emptying secondary to their condition, and Domperidone addresses this issue effectively.Vascular Benefits: Cinnarizine's ability to improve blood flow to the inner ear and brain provides additional benefits beyond symptom control. Enhanced microcirculation may support healing and recovery in conditions where vascular insufficiency contributes to vestibular dysfunction.Side Effects and Safety ConsiderationsLike all medications, CLANARIZINE DOM can cause side effects, though not everyone experiences them. Understanding potential adverse effects helps patients recognize when to seek medical attention and allows healthcare providers to monitor therapy appropriately.Common Side Effects:The most frequently reported side effect of CLANARIZINE DOM is drowsiness or sedation, occurring in approximately 10-20% of patients. This effect is primarily attributable to Cinnarizine's antihistaminic properties. Patients should avoid driving or operating machinery until they know how the medication affects them. Taking the medication at bedtime can minimize daytime drowsiness for some patients.Dry mouth is another common side effect, affecting roughly 10-15% of patients. This occurs due to anticholinergic effects and can be managed by sipping water frequently, chewing sugar-free gum, or using saliva substitutes if severe. Maintaining good oral hygiene is important to prevent dental problems associated with reduced saliva production.Mild gastrointestinal symptoms, including constipation, abdominal discomfort, or changes in bowel habits, may occur. While Domperidone promotes gastric emptying, it can occasionally alter bowel motility. These effects are usually mild and resolve with continued use or dose adjustment.",
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"description": "EPSTATE ED represents an advanced pharmaceutical formulation that combines three powerful therapeutic agents: Pregabalin, Epalrestat, and Methylcobalamin. This innovative triple-combination medication is specifically designed to address the complex pathophysiology of diabetic neuropathy and neuropathic pain conditions. By integrating multiple mechanisms of action, EPSTATE ED offers a comprehensive approach to managing nerve-related complications that significantly impact the quality of life for millions of individuals worldwide.\nThe formulation addresses not only the symptomatic relief of neuropathic pain but also targets the underlying metabolic derangements that contribute to nerve damage progression. This multi-pronged therapeutic strategy makes EPSTATE ED particularly valuable for patients who require more than symptomatic management alone.\nUnderstanding the Active Components\nPregabalin: The Neuropathic Pain Modulator\nPregabalin serves as the cornerstone analgesic component in EPSTATE ED. This anticonvulsant medication works by binding to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. Through this mechanism, Pregabalin reduces the release of excitatory neurotransmitters including glutamate, norepinephrine, and substance P. This reduction in neurotransmitter release effectively dampens the abnormal neural signaling that characterizes neuropathic pain conditions.\nThe molecule demonstrates excellent bioavailability and rapid absorption, allowing patients to experience relief within a relatively short timeframe. Its efficacy in managing various neuropathic pain syndromes has been extensively documented in clinical trials, establishing it as a first-line agent for diabetic peripheral neuropathy, postherpetic neuralgia, and other chronic neuropathic pain conditions.\nEpalrestat: The Aldose Reductase Inhibitor\nEpalrestat represents a unique addition to the formulation, functioning as a selective aldose reductase inhibitor. In diabetic conditions, excess glucose is converted to sorbitol through the polyol pathway, with aldose reductase serving as the rate-limiting enzyme. The accumulation of sorbitol within nerve cells leads to osmotic stress, depletion of myoinositol, and subsequent nerve dysfunction.\nBy inhibiting aldose reductase, Epalrestat prevents this harmful sorbitol accumulation, thereby addressing one of the fundamental metabolic abnormalities responsible for diabetic neuropathy. This disease-modifying approach distinguishes EPSTATE ED from purely symptomatic treatments. Epalrestat has been particularly well-studied in Asian populations and has demonstrated the ability to improve nerve conduction velocities and reduce subjective neuropathic symptoms over time.\nMethylcobalamin: The Neurotropic Vitamin\nMethylcobalamin, the bioactive form of Vitamin B12, completes the therapeutic triad in EPSTATE ED. Unlike cyanocobalamin, which requires conversion in the body, methylcobalamin is immediately available for utilization in crucial biochemical processes. It plays an indispensable role in myelin synthesis, the protective sheath surrounding nerve fibers that enables proper signal transmission.\nThis coenzyme participates in methionine synthesis and is essential for maintaining the structural and functional integrity of neurons. Methylcobalamin also facilitates nerve regeneration and has demonstrated neuroprotective properties in various experimental models. For patients with diabetic neuropathy, who often exhibit Vitamin B12 deficiency (sometimes exacerbated by metformin therapy), supplementation with methylcobalamin addresses both nutritional deficits and supports nerve health at a fundamental level.\nClinical Applications and Uses\nEPSTATE ED is primarily indicated for the comprehensive management of diabetic peripheral neuropathy, a condition affecting approximately 50% of individuals with long-standing diabetes. The symptoms of this condition range from tingling sensations and burning pain to numbness and loss of protective sensation, which can lead to serious complications including foot ulcers and amputations.\nBeyond diabetic neuropathy, EPSTATE ED may be prescribed for various neuropathic pain syndromes where the combination of pain relief, metabolic correction, and nerve support proves beneficial. Patients experiencing chronic nerve pain resulting from metabolic disturbances, nutritional deficiencies, or structural nerve damage may find this combination particularly effective.\nThe medication is typically recommended for adults who have not achieved adequate symptom control with single-agent therapy or who would benefit from the synergistic effects of the three components. Healthcare providers may prescribe EPSTATE ED when a patient requires both immediate symptom relief and long-term disease modification.\nKey Benefits and Therapeutic Advantages\nComprehensive Multi-Mechanism Action\nThe primary advantage of EPSTATE ED lies in its multi-faceted approach to neuropathic conditions. Rather than addressing only pain symptoms, the formulation simultaneously tackles pain perception, underlying metabolic abnormalities, and nutritional support for nerve health. This comprehensive strategy may lead to superior outcomes compared to monotherapy approaches.\nEnhanced Pain Relief\nClinical evidence supporting Pregabalin's efficacy in neuropathic pain is substantial. Patients often report significant reductions in pain intensity, improved sleep quality due to decreased nocturnal pain, and enhanced ability to perform daily activities. The pain-relieving effects typically manifest within the first week of therapy and continue to improve with ongoing treatment.\nDisease Modification Potential\nUnlike purely symptomatic treatments, the inclusion of Epalrestat provides genuine disease-modifying potential. By targeting the polyol pathway, EPSTATE ED may slow the progression of nerve damage in diabetic patients. Long-term use may preserve nerve function and prevent the worsening of neuropathic symptoms, offering hope beyond mere symptom management.\nImproved Nerve Conduction and Function\nThe combination of metabolic correction through Epalrestat and neurotropic support via Methylcobalamin creates an environment conducive to nerve regeneration and functional improvement. Studies have demonstrated improvements in nerve conduction velocity parameters with similar combination therapies, suggesting potential restoration of nerve function rather than simple symptom masking.\nConvenience of Combination Therapy\nFor patients who would otherwise require multiple separate medications, EPSTATE ED offers the convenience of a single tablet containing all three therapeutic agents. This simplification of medication regimens improves compliance, reduces pill burden, and may enhance overall treatment outcomes.\nQuality of Life Enhancement\nThe cumulative effect of pain reduction, improved nerve function, and better metabolic control translates into meaningful quality of life improvements. Patients report better mobility, reduced interference of pain with daily activities, improved mood, and enhanced social functioning.\nPotential Side Effects and Safety Considerations\nCommon Side Effects\nAs with any pharmaceutical agent, EPSTATE ED may produce certain adverse effects. The most commonly reported side effects are primarily attributable to the Pregabalin component and include dizziness, somnolence, peripheral edema, dry mouth, blurred vision, weight gain, and difficulty with concentration or attention. These effects are generally mild to moderate and often diminish with continued therapy as the body adapts to the medication.\nGastrointestinal symptoms such as constipation or nausea may occur, though they are typically manageable with dietary modifications or symptomatic treatment. Some patients experience increased appetite leading to weight gain, which requires monitoring, particularly in diabetic individuals where weight management is crucial.\nSerious but Rare Adverse Events\nThough uncommon, certain serious adverse effects warrant immediate medical attention. These include allergic reactions manifesting as rash, itching, swelling, severe dizziness, or breathing difficulties. Pregabalin has been associated with rare cases of angioedema, which requires prompt discontinuation and medical intervention.\nMental health changes, including mood alterations, anxiety, depression, agitation, or suicidal thoughts, have been reported with Pregabalin use, particularly in individuals with pre-existing psychiatric conditions. Patients and caregivers should remain vigilant for behavioral changes and report them immediately to healthcare providers.\nDrug Interactions and Precautions\nEPSTATE ED may interact with other central nervous system depressants, including alcohol, opioids, benzodiazepines, and antihistamines, potentially intensifying sedation and cognitive impairment. Patients should inform their healthcare provider of all medications, supplements, and substances they consume.\nIndividuals with kidney impairment require dose adjustments since Pregabalin is primarily eliminated through renal excretion. Regular monitoring of renal function may be necessary during long-term therapy.\nSpecial Population Considerations\nPregnant or breastfeeding women should use EPSTATE ED only when clearly necessary and under strict medical supervision, as the safety profile in these populations has not been fully established. Elderly patients may be more susceptible to side effects, particularly dizziness and confusion, necessitating careful dose titration and monitoring.\nPatients should be advised against abrupt discontinuation of EPSTATE ED, as sudden cessation of Pregabalin may precipitate withdrawal symptoms including insomnia, nausea, headache, anxiety, and sweating. Gradual dose reduction under medical supervision is recommended when discontinuing therapy.\nDosage and Administration Guidelines\nThe appropriate dosage of EPSTATE ED is highly individualized and should be determined by a qualified healthcare professional based on the patient's specific condition, response to therapy, and tolerance. Typically, treatment begins with a lower dose that is gradually increased to achieve optimal therapeutic benefit while minimizing adverse effects.\nPatients should take EPSTATE ED exactly as prescribed, with or without food, at consistent times each day to maintain stable blood levels. Missing doses should be addressed by taking the forgotten dose as soon as remembered, unless it's nearly time for the next scheduled dose. Double dosing to compensate for missed doses is not recommended.\nRegular follow-up appointments allow healthcare providers to assess treatment efficacy, monitor for adverse effects, and make necessary dose adjustments. Patients should maintain open communication with their medical team regarding symptom improvement, side effects, and any concerns that arise during therapy.\nPatient Counseling and Lifestyle Recommendations\nMaximizing the benefits of EPSTATE ED extends beyond simply taking the medication. Patients should be counseled on complementary lifestyle measures that support neuropathy management. Maintaining optimal glycemic control remains paramount for diabetic patients, as blood sugar management directly impacts neuropathy progression regardless of medication.\nRegular physical activity, within individual capabilities, promotes circulation, supports nerve health, and may enhance the therapeutic effects of EPSTATE ED. Daily foot examinations become critical for diabetic patients to identify potential injuries early, preventing serious complications.\nNutritional optimization, including adequate intake of B vitamins, antioxidants, and essential nutrients, supports the neurotropic effects of Methylcobalamin. Avoiding alcohol and tobacco, both of which can exacerbate neuropathy, is strongly recommended.\nPatients should be cautioned about activities requiring alertness, such as driving or operating machinery, especially during the initial treatment phase when dizziness and somnolence may be more pronounced. These effects typically improve with continued therapy, but individual responses vary.\nConclusion\nEPSTATE ED represents a thoughtfully designed pharmaceutical formulation that addresses the multifaceted nature of diabetic neuropathy and neuropathic pain through its unique combination of Pregabalin, Epalrestat, and Methylcobalamin. This triple-action approach offers patients more than symptomatic relief—it provides genuine disease modification potential, nutritional support, and comprehensive nerve health optimization.\nThe synergistic effects of these three components create a therapeutic profile that is greater than the sum of its parts. While Pregabalin efficiently manages pain symptoms and improves quality of life in the short term, Epalrestat works to address underlying metabolic derangements that drive disease progression, and Methylcobalamin provides essential neurotropic support for nerve regeneration and function.\nFor patients struggling with the debilitating effects of neuropathic pain and diabetic neuropathy, EPSTATE ED offers renewed hope for better symptom control and potentially slowed disease progression. The convenience of combination therapy in a single tablet improves adherence and simplifies complex treatment regimens.\nHowever, EPSTATE ED is not without considerations. Potential side effects, though generally manageable, require awareness and monitoring. The medication is most effective when integrated into a comprehensive management plan that includes optimal glycemic control, lifestyle modifications, and regular medical supervision.\nUltimately, EPSTATE ED should be viewed as a valuable tool in the therapeutic arsenal against neuropathic conditions, best utilized under the guidance of knowledgeable healthcare professionals who can individualize treatment to each patient's unique needs and circumstances. With proper use, monitoring, and patient education, EPSTATE ED can significantly improve outcomes and quality of life for those affected by these challenging neurological conditions.",
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"description": "Product Name: FLAVOSHIELD 500\nActive Ingredients: Micronized Purified Flavonoid Fraction (MPFF) 500mg, containing Diosmin 450mg and Hesperidin 50mg.\nPresentation: Oral Tablets\n\nUnveiling FLAVOSHIELD 500: A Deep Dive into Advanced Venous and Vascular Wellness\nIn the intricate network of the human circulatory system, veins perform the silent, relentless task of returning blood to the heart against gravity. When this system faces strain, it can manifest through discomfort, heaviness, and visible changes that impact both physical well-being and quality of life. Enter FLAVOSHIELD 500, a sophisticated pharmaceutical-grade formulation designed to fortify venous health at its core. Powered by a Micronized Purified Flavonoid Fraction (MPFF)—a precise blend of 450mg Diosmin and 50mg Hesperidin—FLAVOSHIELD 500 represents a pinnacle in venoactive therapy. This comprehensive description explores the product, its mechanism, multifaceted uses, key benefits, safety profile, and its role in a holistic health strategy.\n\nWhat is FLAVOSHIELD 500? The Science of MPFF\nFLAVOSHIELD 500 is not a simple herbal supplement; it is a clinically researched, standardized medical treatment. Its active core, the Micronized Purified Flavonoid Fraction, is derived from citrus fruits but undergoes a specialized purification and micronization process. This technological advancement is crucial:\n\nPurification: Ensures a consistent, high-potency concentration of the active flavonoid molecules, Diosmin and Hesperidin, free from plant impurities.\nMicronization: Reduces the particle size of the flavonoids dramatically, increasing their surface area. This leads to significantly enhanced absorption in the gastrointestinal tract, ensuring that a much higher percentage of the active dose reaches the bloodstream and, ultimately, the target venous tissues. Compared to non-micronized diosmin, MPFF offers up to 30% greater bioavailability, making FLAVOSHIELD 500 a more effective and reliable choice.\nThis synergy of Diosmin and Hesperidin works on multiple physiological pathways to restore venous tone and capillary integrity.\n\nPrimary Uses and Therapeutic Applications\nFLAVOSHIELD 500 is indicated for the management of various stages of chronic venous disorders and related conditions:\n\nChronic Venous Disease (CVD) & Venous Insufficiency: This is the primary use. It alleviates the distressing symptoms stemming from weakened vein walls and faulty valves in the legs. These include:\n\nHeaviness and Fatigue: The pervasive feeling of weight and tiredness in the legs, especially after prolonged standing or sitting.\nPain and Aching: Dull, throbbing, or cramping pain that improves with elevation.\nSwelling (Edema): Reduction of ankle and lower leg swelling caused by fluid leakage from capillaries.\nNocturnal Cramps: Relief from painful muscle spasms that often occur at night.\nHemorrhoidal Disease (Acute and Chronic): MPFF is a cornerstone in hemorrhoid management. It treats acute hemorrhoidal attacks by reducing bleeding, pain, and discharge. For chronic cases, it helps prevent recurrences by decreasing capillary fragility and inflammation in the anal venous plexus.\n\nPost-Phlebitic Syndrome: Following deep vein thrombosis (DVT), patients often suffer from chronic leg swelling, pain, and skin changes. FLAVOSHIELD 500 can be part of the management plan to improve microcirculation and reduce symptoms.\n\nSupport Post-Sclerotherapy or Surgical Procedures: It is commonly used after vein stripping, laser ablation, or sclerotherapy to support healing, reduce postoperative swelling and bruising, and help consolidate results.\n\nKey Benefits and Mechanism of Action: The Multi-Target Approach\nThe efficacy of FLAVOSHIELD 500 stems from its multi-faceted pharmacological actions on the venous and lymphatic systems:\n\nVenotonic Action: It increases venous tone and elasticity by promoting the contraction of smooth muscle in the vein walls. This helps veins propel blood more efficiently upward, reducing pooling and pressure. Think of it as “tightening” slackened venous structures.\n\nCapillary-Protective & Anti-Inflammatory Effects: It strengthens capillary walls (reduces capillary permeability) and inhibits the release of inflammatory mediators (like prostaglandins and leukotrienes). This dual action minimizes the leakage of fluid, proteins, and inflammatory cells into surrounding tissues, thereby directly addressing edema (swelling) and inflammation. This is particularly vital in hemorrhoidal tissue.\n\nLymphatic Enhancement: FLAVOSHIELD 500 has been shown to increase lymphatic drainage by boosting the frequency and intensity of lymphatic contractions. This provides an additional route for removing excess interstitial fluid and proteins, further reducing swelling.\n\nAntioxidant Activity: The flavonoids scavenge harmful free radicals, protecting venous and capillary endothelial cells from oxidative stress, which is a contributing factor in chronic venous disease.\n\nImprovement of Microcirculation: By reducing blood viscosity and inhibiting red blood cell aggregation, it improves blood flow in the smallest vessels, enhancing oxygen delivery and waste removal at the tissue level.\n\nPatient-Centric Benefits:\n\nRapid Symptom Relief: Patients often report a noticeable decrease in leg heaviness and pain within the first few weeks of treatment.\nEnhanced Quality of Life: Restores the ability to stand, walk, and engage in daily activities with greater comfort and less discomfort.\nReduced Reliance on Pain Medication: By addressing the underlying inflammation and pain of venous issues and hemorrhoids, it can decrease the need for NSAIDs.\nComplement to Compression Therapy: Works synergistically with compression stockings, often allowing for better tolerance and compliance with compression wear.\nSide Effects and Safety Profile: What to Expect\nFLAVOSHIELD 500 is generally very well-tolerated, with a low incidence of side effects, which are typically mild and transient. This excellent safety profile is a result of its natural origin and high purification.\n\nCommon Side Effects (Rare and usually mild):\n\nGastrointestinal: Some individuals may experience mild, transient digestive disturbances such as nausea, stomach pain, diarrhea, or heartburn. Taking the tablet with a meal can often mitigate this.\nNeurological: Occasional reports of headache or dizziness.\nAllergic Reactions: Very rare cases of skin rash or itching have been reported.\nImportant Safety Considerations:\n\nPregnancy and Lactation: While no teratogenic effects have been demonstrated, as a precaution, use during pregnancy (especially the first trimester) and breastfeeding should only be under the direct supervision of a physician who has weighed the benefits against potential risks.\nDrug Interactions: No significant pharmacokinetic drug interactions have been formally reported. However, as with any medication, it is prudent to inform your doctor about all other medicines and supplements you are taking.\nContraindications: Hypersensitivity to any of the components (Diosmin, Hesperidin, or excipients in the tablet) is a contraindication.\nCrucial Note: FLAVOSHIELD 500 is a treatment for symptoms and a stabilizer of venous function, not a cure for underlying venous valve incompetence. It does not replace definitive interventional treatments (like ablation or surgery) for advanced varicose veins when they are medically indicated. It is essential to receive a proper diagnosis from a healthcare professional to rule out other causes of leg swelling or pain (e.g., cardiac, renal, or hepatic origin).\n\nConclusion: FLAVOSHIELD 500 – A Cornerstone of Comprehensive Venous Care\nIn conclusion, FLAVOSHIELD 500 stands as a robust, scientifically validated agent in the realm of vascular health. Its advanced MPFF technology, combining 450mg of micronized Diosmin with 50mg of Hesperidin, delivers enhanced bioavailability and a powerful, multi-target action that addresses the root causes of venous discomfort: poor tone, capillary fragility, inflammation, and impaired lymphatic drainage.\n\nWhether battling the daily fatigue of heavy legs, managing the acute distress of a hemorrhoidal flare-up, or supporting recovery after a venous procedure, FLAVOSHIELD 500 offers a reliable and well-tolerated therapeutic option. Its benefits in improving symptoms and quality of life are clear, backed by a strong body of clinical evidence.\n\nHowever, optimal venous health is a holistic endeavor. FLAVOSHIELD 500 should be viewed as the pharmacological cornerstone of a broader management plan. This plan should include:\n\nMedical Supervision: Regular consultation with a vascular specialist or phlebologist.\nLifestyle Modifications: Weight management, regular low-impact exercise (walking, swimming), and elevation of the legs.\nCompression Therapy: The use of medically prescribed compression stockings when recommended.\nDietary Awareness: A fiber-rich diet to prevent constipation and straining.\nBy integrating FLAVOSHIELD 500 into this comprehensive approach, individuals can take proactive control of their venous health, shielding their vitality and comfort from the burdens of venous insufficiency. Always consult your healthcare provider to determine if FLAVOSHIELD 500 is appropriate for your specific condition and to establish the correct dosage and treatment duration.\n\nDisclaimer: This content is for informational purposes only and does not constitute medical advice. Always seek the guidance of a qualified healthcare professional with any questions regarding a medical condition or treatment. Do not delay seeking or disregard professional medical advice based on information contained here.",
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"description": "Ferric Diphosphate Ferric Pyrophosphate With Vitamin C Vitamin B12, and Folic Acid Tablets\nIntroduction to RUDIX FE PRO TABLETS\n\nRUDIX FE PRO TABLETS is a scientifically formulated nutritional supplement designed to help support healthy iron levels, improve red blood cell production, and promote overall wellness. This advanced combination of Ferric Di-Phosphate, Ferric Pyrophosphate, Vitamin C, Vitamin B12, and Folic Acid works together to address iron deficiency, nutritional anemia, weakness, fatigue, and low energy levels.\n\nIron deficiency is one of the most common nutritional deficiencies worldwide, especially among women, pregnant women, elderly individuals, and people with poor dietary intake. Low iron levels can lead to symptoms such as tiredness, pale skin, dizziness, weakness, headache, shortness of breath, and poor concentration. RUDIX FE PRO TABLETS helps replenish essential nutrients that the body requires for proper blood formation and oxygen transportation.\n\nThe carefully selected ingredients in RUDIX FE PRO TABLETS not only support iron absorption but also help improve hemoglobin levels naturally. Vitamin C enhances iron absorption in the body, while Vitamin B12 and Folic Acid support healthy nerve function and red blood cell production.\n\nThis supplement is widely recommended for individuals experiencing nutritional deficiencies, anemia, post-illness weakness, pregnancy-related iron deficiency, and chronic fatigue. With regular use under medical supervision, RUDIX FE PRO TABLETS may help improve energy, immunity, and overall physical performance.\n\nComposition of RUDIX FE PRO TABLETS\n\nRUDIX FE PRO TABLETS contains a balanced combination of essential nutrients including:\n\nFerric Di-Phosphate\nFerric Pyrophosphate\nVitamin C\nVitamin B12\nFolic Acid\n\nEach ingredient plays a vital role in maintaining healthy blood cells and supporting overall body functions.\n\nWhat Is Ferric Di-Phosphate Ferric Pyrophosphate With Vitamin C Vitamin B12 And Folic Acid Tablets?\n\nFerric Di-Phosphate Ferric Pyrophosphate With Vitamin C Vitamin B12 And Folic Acid Tablets is a nutritional supplement used to prevent and treat iron deficiency and anemia. It provides highly bioavailable iron along with vitamins that assist in proper iron utilization and blood cell production.\n\nThis formulation is particularly beneficial for:\n\nIron deficiency anemia\nNutritional deficiencies\nFatigue and weakness\nPregnancy-related anemia\nLow hemoglobin levels\nPoor immunity due to nutritional imbalance\nRecovery after surgery or illness\nElderly individuals with low nutrient absorption\n\nThe synergistic combination helps improve oxygen circulation in the body, which may result in better energy levels and improved physical and mental performance.\n\nHow RUDIX FE PRO TABLETS Works\n\nRUDIX FE PRO TABLETS works by supplying essential nutrients that help the body produce healthy red blood cells and maintain adequate hemoglobin levels.\n\nFerric Di-Phosphate and Ferric Pyrophosphate\n\nThese are iron compounds that help replenish iron stores in the body. Iron is necessary for hemoglobin formation, which carries oxygen from the lungs to different parts of the body. Adequate iron levels support healthy blood circulation and energy production.\n\nVitamin C\n\nVitamin C enhances the absorption of iron from the gastrointestinal tract. It converts iron into a form that is easier for the body to absorb and utilize effectively.\n\nVitamin B12\n\nVitamin B12 plays an essential role in nerve health and red blood cell formation. Deficiency of Vitamin B12 can lead to weakness, fatigue, and neurological issues.\n\nFolic Acid\n\nFolic Acid supports DNA synthesis and red blood cell maturation. It is especially important during pregnancy for fetal development and prevention of birth defects.\n\nTogether, these nutrients work synergistically to support healthy blood production and overall wellness.\n\nUses of RUDIX FE PRO TABLETS\n\nRUDIX FE PRO TABLETS is commonly used for several health conditions related to nutritional deficiency and low iron levels.\n\n1. Treatment of Iron Deficiency Anemia\n\nIron deficiency anemia occurs when the body lacks enough iron to produce healthy hemoglobin. This condition may cause tiredness, weakness, dizziness, pale skin, and reduced physical performance. RUDIX FE PRO TABLETS helps restore iron levels and improve hemoglobin production.\n\n2. Prevention of Nutritional Deficiencies\n\nPeople with poor dietary habits or inadequate nutrient intake may develop deficiencies of iron, Vitamin B12, and folic acid. This supplement helps maintain proper nutritional balance.\n\n3. Support During Pregnancy\n\nPregnant women often require additional iron and folic acid for fetal growth and increased blood volume. RUDIX FE PRO TABLETS may help prevent pregnancy-related anemia and support maternal health.\n\n4. Recovery After Surgery or Illness\n\nAfter major illness, surgery, or blood loss, the body may require additional nutrients to recover effectively. This formulation helps restore energy and improve recovery.\n\n5. Chronic Fatigue and Weakness\n\nLow hemoglobin and nutritional deficiencies can lead to constant tiredness and low stamina. RUDIX FE PRO TABLETS helps improve oxygen supply throughout the body and supports energy production.\n\n6. Elderly Nutritional Support\n\nOlder adults may experience reduced nutrient absorption and poor appetite. This supplement provides essential nutrients necessary for maintaining healthy blood and energy levels.\n\n7. Vegetarian or Vegan Nutritional Support\n\nIndividuals following vegetarian or vegan diets may have a higher risk of Vitamin B12 and iron deficiency. RUDIX FE PRO TABLETS helps fulfill nutritional requirements.\n\nKey Benefits of RUDIX FE PRO TABLETS\nHelps Increase Hemoglobin Levels\n\nThe iron content in RUDIX FE PRO TABLETS supports healthy hemoglobin production, helping improve oxygen transportation throughout the body.\n\nReduces Weakness and Fatigue\n\nBy improving iron and vitamin levels, this supplement may help reduce tiredness, weakness, and low energy.\n\nEnhances Iron Absorption\n\nVitamin C improves the absorption and utilization of iron, making the formulation more effective.\n\nSupports Healthy Red Blood Cell Production\n\nVitamin B12 and folic acid contribute to the production and maturation of healthy red blood cells.\n\nPromotes Better Energy Levels\n\nImproved oxygen circulation helps boost physical strength and stamina.\n\nSupports Brain and Nerve Function\n\nVitamin B12 plays an important role in maintaining healthy nerve function and cognitive performance.\n\nBeneficial During Pregnancy\n\nFolic acid supports healthy fetal development and helps reduce the risk of neural tube defects.\n\nHelps Maintain Overall Wellness\n\nAdequate iron and vitamin levels contribute to better immunity, improved metabolism, and general health.\n\nAdvantages of Ferric Pyrophosphate in RUDIX FE PRO TABLETS\n\nFerric Pyrophosphate is considered a highly effective and well-tolerated form of iron. Compared to some traditional iron salts, it may cause fewer gastrointestinal side effects in certain individuals.\n\nBenefits include:\n\nBetter iron bioavailability\nImproved patient compliance\nReduced stomach irritation\nEffective support for iron replenishment\nSustained improvement in hemoglobin levels\n\nIts inclusion in RUDIX FE PRO TABLETS makes the formulation highly suitable for individuals requiring long-term iron supplementation.\n\nImportance of Vitamin C in Iron Supplements\n\nVitamin C is an essential nutrient that significantly improves iron absorption. Without adequate Vitamin C, iron absorption from the digestive tract may be reduced.\n\nKey benefits of Vitamin C include:\n\nImproves iron utilization\nSupports immunity\nActs as an antioxidant\nPromotes skin and tissue health\nHelps reduce oxidative stress\n\nThe presence of Vitamin C in RUDIX FE PRO TABLETS enhances the overall effectiveness of the formulation.\n\nRole of Vitamin B12 and Folic Acid\n\nVitamin B12 and Folic Acid are essential vitamins required for healthy blood cell formation.\n\nVitamin B12 Benefits\nSupports nerve function\nHelps produce healthy red blood cells\nSupports brain health\nHelps reduce fatigue\nMaintains energy metabolism\nFolic Acid Benefits\nSupports cell growth and development\nEssential during pregnancy\nHelps prevent folate deficiency anemia\nSupports DNA synthesis\nPromotes healthy fetal development\n\nTogether, these vitamins help improve the body’s ability to maintain healthy blood and energy levels.\n\nDosage of RUDIX FE PRO TABLETS\n\nRUDIX FE PRO TABLETS should be taken exactly as advised by a healthcare professional.\n\nGeneral guidelines may include:\n\nUsually taken once daily or as prescribed\nSwallow the tablet with water\nPreferably taken after meals to reduce stomach discomfort\nDo not exceed the recommended dosage\n\nThe dosage may vary depending on age, medical condition, pregnancy status, and severity of deficiency.\n\nPrecautions While Using RUDIX FE PRO TABLETS\n\nBefore using RUDIX FE PRO TABLETS, it is important to follow certain precautions.\n\nConsult a Healthcare Professional\n\nAlways consult a doctor before starting any nutritional supplement, especially if you have an existing medical condition.\n\nInform About Existing Diseases\n\nPatients with liver disorders, kidney disease, stomach ulcers, or iron overload disorders should inform their healthcare provider.\n\nPregnancy and Breastfeeding\n\nThis supplement is commonly prescribed during pregnancy and breastfeeding, but it should still be used under medical supervision.\n\nKeep Out of Reach of Children\n\nAccidental overdose of iron-containing products can be harmful to children.\n\nAvoid Self-Medication\n\nExcessive iron intake without proper diagnosis may lead to complications.\n\nSide Effects of RUDIX FE PRO TABLETS\n\nLike all supplements and medicines, RUDIX FE PRO TABLETS may cause side effects in some individuals. Most side effects are mild and temporary.\n\nCommon Side Effects\nNausea\nConstipation\nStomach discomfort\nDark-colored stools\nMild abdominal pain\nDiarrhea\nMetallic taste in the mouth\n\nThese side effects usually improve as the body adjusts to the supplement.\n\nSerious Side Effects\n\nAlthough rare, some people may experience serious side effects such as:\n\nSevere allergic reactions\nSwelling of face or throat\nDifficulty breathing\nSevere vomiting\nSevere abdominal pain\nSeek immediate medical attention if any severe symptoms occur.",
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"description": "Maintaining a healthy digestive system is essential for overall well-being. Constipation, especially chronic or severe cases, can significantly affect quality of life and may lead to complications if left untreated. LACTUSMOOTH ENEMA, formulated with Lactulose Enema 20% w/v, is a clinically trusted solution designed to provide rapid and effective relief from constipation and related conditions. It works gently yet efficiently, making it suitable for patients requiring immediate bowel evacuation or management of specific medical conditions.\n\nWhat is LACTUSMOOTH ENEMA?\n\nLACTUSMOOTH ENEMA is a rectal preparation containing Lactulose 20% w/v, a synthetic disaccharide widely used as an osmotic laxative. Unlike oral laxatives, this enema formulation delivers the medication directly into the rectum, ensuring faster action and targeted relief. It is particularly useful in cases where oral administration is not feasible or when quick bowel clearance is required.\n\nLactulose works by drawing water into the bowel, softening stools and stimulating bowel movement without causing harsh irritation.\n\nHow Does Lactulose Enema Work?\n\nLactulose is not digested in the small intestine. Instead, it reaches the colon unchanged, where it is broken down by beneficial gut bacteria into organic acids such as lactic acid and acetic acid. This process:\n\nIncreases osmotic pressure in the colon\nPulls water into the bowel\nSoftens hardened stools\nStimulates natural bowel movement\n\nAdditionally, it helps reduce ammonia absorption in the gut, making it beneficial in certain liver-related conditions like hepatic encephalopathy.\n\nUses of LACTUSMOOTH ENEMA\n\nLACTUSMOOTH ENEMA is prescribed in a variety of medical situations, including:\n\n1. Treatment of Severe Constipation\n\nIt provides fast relief from acute or chronic constipation, especially when oral laxatives fail or are unsuitable.\n\n2. Bowel Cleansing Before Procedures\n\nUsed before surgeries, colonoscopy, or diagnostic procedures to ensure the bowel is completely cleared.\n\n3. Management of Hepatic Encephalopathy\n\nHelps reduce blood ammonia levels by promoting its excretion through stool, thereby supporting liver health.\n\n4. Fecal Impaction\n\nEffective in softening and removing impacted stool in the rectum.\n\n5. Post-Surgical Bowel Care\n\nAssists in maintaining smooth bowel movements after surgeries, especially abdominal or rectal procedures.\n\nKey Benefits of LACTUSMOOTH ENEMA\n✔ Fast-Acting Relief\n\nSince it is administered rectally, it works quicker than oral laxatives, often producing results within a short time.\n\n✔ Gentle on the Intestines\n\nUnlike stimulant laxatives, lactulose works naturally without causing irritation or dependency.\n\n✔ Effective Stool Softening\n\nHelps soften hard stools, making bowel movements painless and comfortable.\n\n✔ Dual Action in Liver Disorders\n\nReduces ammonia absorption, aiding in the treatment of hepatic encephalopathy.\n\n✔ Suitable for Various Patient Groups\n\nCan be used in elderly patients, bedridden individuals, and those unable to take oral medications.\n\n✔ Non-Habit Forming\n\nDoes not cause dependency when used as directed by a healthcare professional.\n\nDirections for Use\nUse as directed by a physician.\nThe enema is usually administered rectally using the provided applicator.\nThe patient is advised to lie on their side during administration.\nRetain the solution for as long as possible to achieve maximum effectiveness.\n\nNote: Proper hygiene and correct administration technique are essential for best results.\n\nSide Effects of LACTUSMOOTH ENEMA\n\nLike all medications, LACTUSMOOTH ENEMA may cause some side effects, although not everyone experiences them.\n\nCommon Side Effects:\nMild abdominal discomfort\nBloating or gas\nRectal irritation\nCramping\nLess Common Side Effects:\nDiarrhea (if overused)\nElectrolyte imbalance\nNausea\nSerious Side Effects (Rare):\nSevere abdominal pain\nPersistent diarrhea\nDehydration\n\nIf any severe or persistent symptoms occur, medical attention should be sought immediately.\n\nPrecautions and Warnings\nUse only under medical supervision.\nNot recommended for patients with intestinal obstruction unless advised by a doctor.\nUse cautiously in patients with diabetes, as lactulose contains sugars.\nAvoid overuse to prevent electrolyte imbalance.\nMaintain adequate hydration during treatment.\n\nPregnant and breastfeeding women should consult a healthcare provider before use.\n\nStorage Instructions\nStore in a cool and dry place.\nKeep away from direct sunlight.\nDo not freeze.\nKeep out of reach of children.\nWhy Choose LACTUSMOOTH ENEMA?\n\nIn today’s fast-paced lifestyle, digestive issues like constipation are becoming increasingly common. LACTUSMOOTH ENEMA stands out as a reliable, safe, and effective solution due to its:\n\nClinically proven formulation\nRapid onset of action\nGentle and non-irritating mechanism\nVersatile usage in multiple conditions\n\nIt is especially beneficial in hospital settings and for home care patients requiring immediate relief.\n\nConclusion\n\nLACTUSMOOTH ENEMA (Lactulose Enema 20% w/v) is a highly effective and dependable treatment for constipation, bowel cleansing, and hepatic encephalopathy management. Its osmotic action ensures gentle yet efficient relief without causing dependency or harsh side effects. Whether used for acute constipation or as part of a broader medical treatment plan, it delivers consistent and safe results.",
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