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"name": "Glimepiride IP1 mg, Voglibose IP 0.2 MG & Metformin Hydrochloride IP 500 mg ",
"description": "GLIMITERIS MV1 0.2 is an advanced fixed-dose combination (FDC) medication designed for adults with Type 2 Diabetes Mellitus (T2DM) who require more than lifestyle modifications or single/dual therapy to maintain optimal blood sugar levels. This innovative formulation brings together the power of three well-established antidiabetic agents—Glimepiride (1 mg), Voglibose (0.2 mg), and Metformin Hydrochloride SR (500 mg)—to provide comprehensive glycemic control.\n\nIt is particularly effective for patients struggling with postprandial hyperglycemia, fasting glucose regulation, and HbA1c reduction, making it a preferred choice in cases of poorly controlled diabetes.\n\n \n\nMechanism of Action\nThe therapeutic benefit of GLIMITERIS MV1 0.2 comes from the unique synergy of its three components, each targeting different aspects of glucose metabolism:\n\n1. Glimepiride (1 mg) – Sulfonylurea\nStimulates insulin secretion by activating pancreatic beta cells.\n\nProvides a long-lasting effect with comparatively lower hypoglycemia risk than older sulfonylureas.\n\nHelps reduce both fasting and postprandial glucose levels.\n\n2. Voglibose (0.2 mg) – Alpha-Glucosidase Inhibitor\nDelays the breakdown and absorption of carbohydrates in the intestine.\n\nMinimizes post-meal glucose spikes (PPBG).\n\nActs locally in the gut and has minimal systemic absorption, which reduces systemic side effects.\n\n3. Metformin Hydrochloride SR (500 mg) – Biguanide\nDecreases hepatic glucose production (gluconeogenesis).\n\nImproves peripheral insulin sensitivity, enhancing glucose uptake in muscles.\n\nDoes not cause hypoglycemia on its own.\n\nThe sustained-release (SR) formulation ensures extended control and reduces gastrointestinal side effects.\n\n \n\nIndications\nGLIMITERIS MV1 0.2 is indicated for:\n\nAdults with Type 2 Diabetes Mellitus.\n\nPatients inadequately controlled with monotherapy or dual therapy.\n\nManagement of fasting and postprandial hyperglycemia.\n\nLong-term HbA1c reduction as part of a comprehensive diabetes care plan.\n\n \n\nKey Benefits\n✅ Comprehensive Blood Sugar Control – Acts on fasting, post-meal, and long-term HbA1c levels.\n✅ Postprandial Spike Management – Voglibose effectively controls carbohydrate-induced sugar surges.\n✅ Reduced Pill Burden – Combines three medicines into a single tablet.\n✅ Lower Hypoglycemia Risk – Metformin and Voglibose balance out Glimepiride’s insulin-secreting effect.\n✅ Weight Management Support – Metformin may promote modest weight loss or prevent weight gain.\n✅ Improved Tolerability – SR formulation of Metformin enhances gastrointestinal comfort.\n\n \n\nDosage and Administration\nRecommended dose: One tablet once or twice daily with meals, or as directed by the physician.\n\nAdministration tips:\n\nTake with the first bite of a main meal to maximize Voglibose’s effect.\n\nSwallow whole with water; do not crush or chew the SR tablet.\n\nDose adjustments: Based on blood sugar monitoring, clinical response, and renal/hepatic function.\n\n \n\nContraindications\nGLIMITERIS MV1 0.2 is not suitable for patients with:\n\nType 1 diabetes or diabetic ketoacidosis.\n\nSevere renal impairment (eGFR <30 mL/min/1.73 m²).\n\nHepatic dysfunction.\n\nSevere gastrointestinal diseases.\n\nHistory of lactic acidosis.\n\nHypersensitivity to Glimepiride, Voglibose, or Metformin.\n\nPregnancy and lactation (unless strictly advised by a physician).\n\n \n\nWarnings and Precautions\nHypoglycemia: Risk is higher when combined with other antidiabetics or with missed meals.\n\nLactic Acidosis: A rare but life-threatening effect of Metformin—renal function monitoring is essential.\n\nGI Side Effects: Voglibose and Metformin may cause bloating, flatulence, or diarrhea (usually temporary).\n\nVitamin B12 Monitoring: Long-term Metformin use may reduce B12 absorption.\n\nLiver and Kidney Function: Regular monitoring is recommended for safe long-term use.\n\n \n\nAdverse Effects\nCommon:\nGlimepiride: Mild hypoglycemia, dizziness, slight weight gain.\n\nVoglibose: Gas, abdominal discomfort, mild diarrhea.\n\nMetformin SR: Nausea, bloating, metallic taste, loose stools.\n\nRare but Serious:\nLactic acidosis (from Metformin).\n\nSevere hypoglycemia (especially if meals are skipped).\n\nAllergic reactions such as rash, itching, or swelling.\n\nElevated liver enzymes.\n\nSeek medical attention if symptoms such as rapid breathing, confusion, severe fatigue, or muscle pain occur.\n\n \n\nDrug Interactions\nIncreased hypoglycemia risk: With insulin, beta-blockers, and sulfonylureas.\n\nReduced Metformin efficacy: With corticosteroids, estrogens, and diuretics.\n\nLactic acidosis risk: Higher with alcohol or iodinated contrast agents. ",
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"description": "TENELIGOLD PIO 20/15 \nTeneligliptin & Pioglitazone\nIntroduction\nTENELIGOLD PIO 20/15 combines two antidiabetic medications, Teneligliptin and Pioglitazone, in a single formulation. This combination is designed to manage type 2 diabetes mellitus by targeting different aspects of glucose metabolism, thereby improving glycemic control in patients who are inadequately controlled with monotherapy or require dual therapy.\n\nComposition\n\nTeneligliptin: A dipeptidyl peptidase-4 (DPP-4) inhibitor that enhances insulin secretion and reduces glucagon release, thereby lowering blood glucose levels.\nPioglitazone: A thiazolidinedione (TZD) that improves insulin sensitivity in peripheral tissues (muscle and adipose tissue) and reduces hepatic glucose production.\nMechanism of Action\n\nTeneligliptin: Inhibits the degradation of incretin hormones (GLP-1 and GIP), which play a key role in glucose-dependent insulin secretion and suppression of glucagon secretion.\nPioglitazone: Activates peroxisome proliferator-activated receptor gamma (PPAR-γ), leading to improved insulin sensitivity, enhanced glucose uptake in peripheral tissues, and reduced hepatic glucose production.\nIndications\nTENELIGOLD PIO 20/15 is indicated for:\n\nType 2 Diabetes Mellitus: Used to improve glycemic control in adults who are inadequately controlled with diet and exercise alone or with other antidiabetic medications.\nDosage and Administration\n\nThe typical dosage is one tablet of TENELIGOLD PIO 20/15 taken orally once daily, preferably with meals.\nDosage adjustments may be necessary based on individual patient response and tolerability.\nIt is important to adhere to the prescribed dosage regimen to achieve optimal glycemic control.\nSide Effects\nCommon side effects may include:\n\nHypoglycemia (especially when used in combination with insulin or sulfonylureas)\nEdema (fluid retention)\nWeight gain\nHeadache\nNasopharyngitis (common cold)\nMore severe side effects can include:\n\nHeart failure (especially in patients with pre-existing cardiovascular disease)\nHepatic dysfunction (monitor liver function tests periodically)\nBone fractures (especially in women)\nPrecautions\n\nHeart Failure: Use with caution in patients with a history of heart failure or other cardiovascular diseases.\nBladder Cancer: Pioglitazone has been associated with an increased risk of bladder cancer; therefore, it should be used cautiously in patients with a history of bladder cancer or with risk factors.\nLiver Function: Monitor liver function tests before starting treatment and periodically thereafter, as Pioglitazone may cause hepatic dysfunction.\nPregnancy and Lactation: Use during pregnancy and lactation should be avoided unless the potential benefits outweigh the risks.\nDrug Interactions\n\nInsulin/Sulfonylureas: Increased risk of hypoglycemia when used concomitantly with insulin or sulfonylureas.\nGemfibrozil: May increase Pioglitazone levels, requiring dose adjustment.\nCYP2C8 Inhibitors (e.g., Gemfibrozil): May increase Pioglitazone concentrations, necessitating monitoring for adverse effects.\nConclusion\nTENELIGOLD PIO 20/15 offers a dual-action approach to managing type 2 diabetes mellitus by combining Teneligliptin and Pioglitazone. This combination helps improve glycemic control through different mechanisms: enhancing insulin secretion and sensitivity. It is crucial to use this medication under the guidance of a healthcare professional to optimize treatment outcomes while minimizing the risk of side effects. Regular monitoring for efficacy and safety parameters, including blood glucose levels and potential adverse effects, is essential for managing diabetes effectively with TENELIGOLD PIO 20/15.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order NOW\n\n",
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"description": "Fabrical D3 6L \nCholecalciferol Vitamin D3 (600,000IU) Injection\nIntroduction\nFabrical D3 6L is a potent vitamin D3 (Cholecalciferol) injection, providing 600,000 IU per dose. This high-dose formulation is designed to address severe vitamin D deficiency and support overall bone health. It is particularly useful for individuals who cannot achieve adequate vitamin D levels through oral supplements or dietary intake.\n\nComposition\n\nCholecalciferol (Vitamin D3) 600,000 IU: A fat-soluble vitamin essential for the absorption of calcium and phosphorus in the body, playing a crucial role in maintaining bone health and calcium homeostasis.\nMechanism of Action\nCholecalciferol (Vitamin D3) undergoes hydroxylation in the liver to form 25-hydroxyvitamin D, which is then converted in the kidneys to its active form, calcitriol (1,25-dihydroxyvitamin D). Calcitriol enhances the intestinal absorption of calcium and phosphorus, supports bone mineralization, and modulates immune function.\n\nIndications\nFabrical D3 6L is indicated for:\n\nSevere Vitamin D Deficiency: To rapidly correct low levels of vitamin D.\nOsteoporosis: To support bone health and prevent fractures.\nHypocalcemia: To assist in the treatment of low calcium levels due to hypoparathyroidism or other conditions.\nRickets and Osteomalacia: To treat and prevent bone disorders caused by vitamin D deficiency.\nMalabsorption Syndromes: In conditions like Crohn’s disease, celiac disease, and bariatric surgery where vitamin D absorption is impaired.\nDosage and Administration\n\nAdult Dosage: Typically, a single dose of 600,000 IU is administered intramuscularly. The frequency of administration depends on the severity of deficiency and the patient's response to treatment.\nAdministration: The injection should be administered by a healthcare professional. It is important to monitor serum calcium and vitamin D levels during treatment to avoid hypercalcemia and vitamin D toxicity.\nSide Effects\nCommon side effects may include:\n\nPain at the injection site\nMild gastrointestinal disturbances (nausea, vomiting)\nFatigue\nHeadache\nMore severe side effects can include:\n\nHypercalcemia (high calcium levels), which may present with symptoms like weakness, confusion, increased thirst and urination, and abdominal pain.\nHypervitaminosis D, resulting from excessive vitamin D intake.\nPrecautions\n\nHypercalcemia: Patients should be monitored for signs of elevated calcium levels.\nKidney Function: Use with caution in patients with renal impairment as vitamin D metabolism and excretion may be affected.\nPregnancy and Lactation: High doses of vitamin D should be used under medical supervision during pregnancy and lactation.\nDrug Interactions\n\nThiazide Diuretics: May increase the risk of hypercalcemia when used with vitamin D.\nAntiepileptic Drugs: Some antiepileptics may decrease vitamin D levels.\nGlucocorticoids: May reduce the effectiveness of vitamin D by impairing calcium absorption.\nConclusion\nFabrical D3 6L, with its high-dose Cholecalciferol (600,000 IU), provides an effective treatment for severe vitamin D deficiency and related conditions. Its ability to rapidly restore adequate vitamin D levels makes it an essential therapeutic option for individuals with significant deficiencies or those who have difficulty absorbing vitamin D. As with any high-dose supplementation, it is critical to use this medication under the guidance of a healthcare professional to ensure safety and efficacy, with regular monitoring to prevent potential side effects such as hypercalcemia and vitamin D toxicity.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order NOW\n",
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"description": "ZENCOBAL 1500 I.V. \nMecobalamin Injection 1500 mcg/ml\nOverview\nZENCOBAL 1500 I.V. is a high-potency injectable solution of Mecobalamin, providing 1500 mcg/ml. Mecobalamin, also known as Methylcobalamin, is a bioactive form of Vitamin B12 essential for nerve function, red blood cell production, and DNA synthesis. This injectable form is particularly beneficial for individuals with severe Vitamin B12 deficiency, absorption issues, or those requiring rapid therapeutic response.\n\nBenefits of Mecobalamin\n\nNeurological Health\n\nEssential for the maintenance and regeneration of myelin sheaths, which protect nerve fibers.\nHelps in the prevention and treatment of neuropathy, which can cause symptoms like tingling, numbness, and pain in the extremities.\nSupports cognitive functions and may improve symptoms in conditions like Alzheimer's disease and other cognitive impairments.\nRed Blood Cell Production\n\nVital for the production of healthy red blood cells, preventing megaloblastic anemia.\nEnhances oxygen transport throughout the body, reducing symptoms of fatigue and weakness.\nDNA Synthesis and Repair\n\nPlays a critical role in the synthesis and repair of DNA, supporting cell division and overall cellular health.\nImportant for rapidly dividing cells, such as those in the bone marrow, skin, and gastrointestinal tract.\nUsage and Dosage\nZENCOBAL 1500 I.V. should be administered under the supervision of a healthcare professional. The dosage and frequency will depend on the severity of the deficiency and the individual's response to treatment. Typically, it may be given as an intramuscular or intravenous injection, ensuring rapid absorption and immediate therapeutic effects.\n\nIndications for Use\n\nVitamin B12 Deficiency: Effective in treating severe deficiencies, particularly in cases where oral supplementation is insufficient.\nPeripheral Neuropathy: Used to alleviate symptoms and promote nerve health in conditions such as diabetic neuropathy, alcoholic neuropathy, and other neuropathic conditions.\nMegaloblastic Anemia: Corrects anemia caused by Vitamin B12 deficiency, improving hemoglobin levels and reducing related symptoms.\nNeurodegenerative Disorders: Supports neurological health and may benefit conditions like multiple sclerosis and amyotrophic lateral sclerosis (ALS).\nSide Effects\nZENCOBAL 1500 I.V. is generally well-tolerated, with minimal side effects. However, some individuals may experience mild reactions at the injection site, such as pain, redness, or swelling. Rarely, systemic reactions like dizziness, headache, or gastrointestinal disturbances may occur. It is important to discuss any pre-existing conditions or medications with a healthcare provider before starting treatment.\n\nPrecautions and Contraindications\n\nAllergic Reactions: Individuals with a known allergy to cobalamin or any component of the injection should avoid use.\nMedical Conditions: Patients with Leber's disease or other hereditary optic neuropathies should use Mecobalamin with caution, as it may exacerbate these conditions.\nPregnancy and Lactation: While Vitamin B12 is crucial during pregnancy and lactation, it is essential to consult a healthcare provider to determine the appropriate dosage and method of administration.\nConclusion\nZENCOBAL 1500 I.V. offers a potent and effective solution for individuals with severe Vitamin B12 deficiency and related conditions. By providing a high dose of bioactive Mecobalamin, this injectable form ensures rapid absorption and immediate therapeutic benefits, supporting neurological health, red blood cell production, and overall cellular function. Under the guidance of a healthcare professional, ZENCOBAL 1500 I.V. can play a critical role in addressing deficiencies, alleviating symptoms, and improving the quality of life for those in need.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order NOW\n",
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"description": "Sitagliptin 50mg, Metformin Hydrochloride 500mg & Glimepiride 2mg is a combination oral medication designed for the effective management of type 2 diabetes mellitus. This triple-action formula works synergistically to control blood glucose levels by addressing insulin resistance, enhancing insulin secretion, and regulating post-meal sugar spikes. Ideal for patients who require more than one mechanism to maintain stable blood sugar, this combination is often prescribed when monotherapy or dual therapy is insufficient.\n\nUses\n\nManagement of Type 2 Diabetes Mellitus in adults.\n\nHelps in controlling fasting and postprandial blood glucose levels.\n\nRecommended for patients whose blood sugar is not adequately controlled with a single antidiabetic medicine.\n\nCan be used as part of a comprehensive diabetes management plan, including diet and exercise.\n\nKey Benefits\n\nDual Mechanism Control:\n\nMetformin Hydrochloride reduces hepatic glucose production and improves insulin sensitivity.\n\nGlimepiride stimulates pancreatic beta cells to secrete more insulin.\n\nSitagliptin enhances incretin hormones, leading to better regulation of post-meal glucose levels.\n\nEffective Blood Sugar Management:\nHelps maintain optimal fasting and postprandial glucose levels, reducing the risk of diabetes-related complications.\n\nConvenient Combination Therapy:\nCombines three mechanisms in a single tablet, reducing the pill burden and improving patient compliance.\n\nSupports Overall Health:\nHelps prevent long-term complications such as neuropathy, nephropathy, retinopathy, and cardiovascular risks associated with diabetes.\n\nPossible Side Effects\n\nWhile generally well-tolerated, some patients may experience:\n\nGastrointestinal issues: nausea, vomiting, diarrhea, or abdominal discomfort (mainly from Metformin).\n\nHypoglycemia (low blood sugar): more likely due to Glimepiride; symptoms include dizziness, sweating, or shakiness.\n\nAllergic reactions: rash, itching, or swelling in rare cases.\n\nOther mild effects: headache, fatigue, or minor changes in taste.\n\nNote: Patients should always consult their doctor before starting this combination and report any unusual symptoms immediately.\n\nConclusion\n\nThe Sitagliptin, Metformin Hydrochloride & Glimepiride combination provides a powerful, multi-targeted approach to managing type 2 diabetes. By tackling high blood sugar from different angles, it supports better glucose control, enhances overall quality of life, and reduces the risk of diabetes-related complications. When used alongside proper diet, exercise, and medical guidance, this combination can be a cornerstone in effective diabetes management.",
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"description": "TELAVINCE AF 25 is primarily indicated for:\n\nHypertension (High Blood Pressure): Effectively helps in lowering elevated blood pressure.\n\nCardiovascular Risk Reduction: Supports heart health and reduces the risk of heart attack, stroke, and other complications related to high blood pressure.\n\nPatients requiring combination therapy: Ideal for individuals who need more than one antihypertensive agent for optimal blood pressure control.\n\nMechanism of Action:\n\nTELAVINCE AF 25 combines two mechanisms for effective blood pressure management:\n\nTelmisartan: Blocks angiotensin II receptors, preventing blood vessel constriction and thereby reducing blood pressure.\n\n[AF Component, e.g., Amlodipine]: Relaxes blood vessels by inhibiting calcium entry into vascular smooth muscles, improving blood flow and reducing strain on the heart.\n\nThis dual-action combination provides better efficacy than single-drug therapy while maintaining a favorable safety profile.\n\nDosage and Administration:\n\nRecommended Dose: As prescribed by a healthcare professional, typically one tablet daily.\n\nRoute: Oral, with water.\n\nTiming: Can be taken with or without food, preferably at the same time each day.\n\nAdjustment: Dose may be adjusted based on individual response and tolerability.\n\nImportant: Always follow your doctor’s instructions. Do not change the dose or stop medication without medical advice.\n\nKey Benefits of TELAVINCE AF 25:\n\nEffective blood pressure control with dual-action therapy.\n\nReduces the risk of cardiovascular complications associated with hypertension.\n\nConvenient once-daily dosing for better patient adherence.\n\nWell-tolerated with minimal side effects.\n\nSuitable for long-term use under medical supervision.\n\nSafety and Precautions:\n\nInform your doctor if you have kidney disease, liver disease, or heart failure.\n\nPregnant or breastfeeding women should use only if recommended by a physician.\n\nAvoid excessive use of potassium-containing salt substitutes.\n\nRegular monitoring of blood pressure and kidney function is recommended.\n\nDo not combine with other angiotensin receptor blockers (ARBs) unless prescribed.\n\nPossible Side Effects:\n\nWhile generally well-tolerated, some patients may experience:\n\nDizziness or lightheadedness\n\nFatigue or weakness\n\nMild swelling of ankles or feet\n\nNausea or headache\n\nSeek immediate medical attention if you experience:\n\nSevere allergic reactions\n\nSwelling of face, lips, or throat\n\nDifficulty breathing\n\nStorage Instructions:\n\nStore in a cool, dry place away from sunlight.\n\nKeep out of reach of children and pets.\n\nDo not use after the expiry date mentioned on the package.\n\nWhy Choose TELAVINCE AF 25:\n\nDeveloped by Steris Healthcare Pvt. Ltd, a trusted pharmaceutical company.\n\nEnsures quality, safety, and efficacy in every tablet.\n\nDesigned for patient convenience with once-daily dosing.\n\nBacked by clinical research for effective hypertension management.\n\nDisclaimer:\n\nThe information provided here is for educational purposes only. TELAVINCE AF 25 should be used only under medical supervision. Consult your healthcare provider for personalized advice. Side effects may vary from person to person.\n\n",
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