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"name": "Rifaximin oral suspension 100mg/5ml",
"description": "Rifaximin Oral Suspension 100 mg/5 ml is a broad-spectrum, gut-selective antibiotic formulated to treat various bacterial infections of the gastrointestinal tract, including traveler’s diarrhea, hepatic encephalopathy-related symptoms, and irritable bowel syndrome with diarrhea (IBS-D). Its unique non-systemic activity ensures that the drug acts locally in the intestines without significant absorption into the bloodstream, making it both effective and safe for long-term gastrointestinal management.\n\nDesigned in a pleasant-tasting, easy-to-administer oral suspension form, Rifaximin 100 mg/5 ml is especially suitable for pediatric patients and adults who have difficulty swallowing tablets. It is ideal for treating infections caused by non-invasive strains of Escherichia coli and other enteric bacteria, while also helping maintain intestinal balance and promoting recovery from gut-related complications.\n\nComposition\n\nEach 5 ml of suspension contains:\n\nRifaximin IP – 100 mg\n\nFlavored base and excipients – q.s.\n\nDosage Form: Oral Suspension\nAppearance: Pink to reddish suspension (depending on brand formulation)\nPackaging: Available in 30 ml, 60 ml, or 100 ml bottles with a measuring cup for accurate dosing.\n\nPharmacological Action and Mechanism\n\nRifaximin belongs to the rifamycin class of antibiotics and is structurally related to rifampicin. However, it has been specially modified to act locally in the gastrointestinal tract with negligible systemic absorption (<0.4%).\n\nMechanism of Action:\n\nRifaximin inhibits bacterial RNA synthesis by binding to the β-subunit of the bacterial DNA-dependent RNA polymerase.\n\nThis action prevents the transcription process, thereby stopping bacterial growth and replication.\n\nIts broad-spectrum activity covers both gram-positive and gram-negative bacteria, including aerobic and anaerobic strains.\n\nDue to poor absorption, it remains in the intestine at high concentrations, providing localized antibacterial effect without systemic toxicity.\n\nAdditionally, Rifaximin exerts eubiotic effects — it helps restore normal intestinal flora balance by selectively targeting harmful bacteria, which makes it useful for chronic intestinal disorders.\n\nUses and Indications\n\nRifaximin Oral Suspension 100 mg/5 ml is indicated for the following conditions:\n\nTraveler’s Diarrhea (TD):\n\nCaused by non-invasive strains of Escherichia coli.\n\nHelps relieve symptoms like watery stools, abdominal cramps, and bloating within a short duration.\n\nHepatic Encephalopathy (HE):\n\nUsed as adjunct therapy to reduce ammonia-producing gut bacteria, thereby lowering blood ammonia levels and improving mental status in patients with chronic liver disease.\n\nIrritable Bowel Syndrome with Diarrhea (IBS-D):\n\nProvides relief from abdominal pain, bloating, and irregular bowel movements by reducing bacterial overgrowth in the small intestine (SIBO).\n\nSmall Intestinal Bacterial Overgrowth (SIBO):\n\nHelps normalize gut flora and reduces gas, bloating, and discomfort caused by bacterial overgrowth.\n\nGastrointestinal Infections in Children:\n\nEffective in pediatric patients suffering from infectious diarrhea due to bacterial contamination of food or water.\n\nProphylactic Use:\n\nMay be prescribed post-surgery or in chronic liver disease to prevent recurrence of infection-related complications.\n\nDosage and Administration\n\nAdults and Children (>12 years): Usual dose is 10–20 ml (200–400 mg) every 8–12 hours, depending on the indication and physician’s recommendation.\n\nChildren (2–12 years): 5–10 ml (100–200 mg) two or three times daily, as directed by a pediatrician.\n\nShake the bottle well before each use.\n\nComplete the prescribed course even if symptoms improve early to prevent recurrence and antibiotic resistance.\n\nKey Benefits\n\nGut-Selective Action:\nActs locally within the intestine without entering systemic circulation, ensuring targeted therapy with minimal side effects.\n\nBroad-Spectrum Antibacterial Activity:\nEffective against a wide range of gram-positive, gram-negative, aerobic, and anaerobic enteric pathogens.\n\nSafe for Pediatric and Adult Use:\nThe liquid form allows accurate dosing and ease of administration, especially for children or elderly patients.\n\nMinimal Systemic Absorption:\nReduces the risk of systemic toxicity and drug interactions compared to conventional antibiotics.\n\nEffective for Traveler’s Diarrhea:\nRapidly controls diarrhea symptoms caused by E. coli and restores normal intestinal function.\n\nImproves Liver Health in Hepatic Encephalopathy:\nDecreases ammonia-producing bacteria, thereby reducing confusion, lethargy, and other symptoms related to hepatic encephalopathy.\n\nRestores Gut Microbiota Balance:\nHelps maintain healthy intestinal flora, supporting digestion and preventing recurrent infections.\n\nReduces Bloating and Abdominal Discomfort in IBS-D:\nProvides symptomatic relief and enhances quality of life in patients suffering from chronic bowel irregularities.\n\nLow Risk of Resistance:\nDue to its minimal absorption and targeted mechanism, the development of bacterial resistance is significantly lower.\n\nWell-Tolerated Formulation:\nThe oral suspension is gentle on the stomach and has a pleasant taste, improving compliance in children and adults alike.\n\nPrecautions and Warnings\n\nWhile Rifaximin Oral Suspension is considered safe for most patients, the following precautions should be observed:\n\nAllergy: Avoid use in patients with known hypersensitivity to rifaximin, rifampicin, or other rifamycin derivatives.\n\nSevere Diarrhea or Bloody Stool: If symptoms worsen or persist beyond 48 hours, consult a physician; may indicate an invasive infection requiring alternative therapy.\n\nLiver Impairment: Use with caution in patients with severe hepatic impairment; dosage adjustments may be required.\n\nPregnancy and Lactation: Limited data available; should be used only if clearly needed and prescribed by a doctor.\n\nLong-Term Use: Prolonged or unnecessary use may lead to superinfection by non-susceptible organisms, including fungi.\n\nDriving and Machinery: Generally safe, but dizziness or fatigue may occur in rare cases.\n\nPossible Side Effects\n\nRifaximin is generally well-tolerated due to its localized action in the gut. However, some mild to moderate side effects may occur in sensitive individuals.\n\nCommon Side Effects:\n\nNausea\n\nFlatulence (gas)\n\nAbdominal pain or cramping\n\nHeadache\n\nBloating\n\nConstipation\n\nLess Common / Rare Side Effects:\n\nSkin rash or itching\n\nDizziness or fatigue\n\nElevated liver enzymes (rare)\n\nVomiting or dry mouth\n\nFever or flu-like symptoms\n\nSerious Side Effects (Very Rare):\n\nAllergic reaction (rash, swelling, or breathing difficulty)\n\nPersistent watery or bloody diarrhea\n\nSevere abdominal pain\n\nIf any severe adverse reactions occur, discontinue use and seek medical attention immediately.\n\nStorage and Handling\n\nStore below 30°C in a cool, dry place.\n\nProtect from direct sunlight and freezing.\n\nShake well before use.\n\nKeep out of reach of children.\n\nDiscard any unused portion after the treatment course or expiry date.\n\nConclusion\n\nRifaximin Oral Suspension 100 mg/5 ml is a clinically trusted and patient-friendly antibiotic formulation for the treatment of gastrointestinal infections and liver-related complications. Its unique non-systemic mode of action, combined with broad antibacterial efficacy, makes it an excellent choice for both acute and chronic intestinal disorders.\n\nUnlike traditional antibiotics that circulate systemically, Rifaximin works locally within the intestines to eliminate harmful bacteria while preserving the natural gut flora. This results in faster relief from symptoms like diarrhea, bloating, and abdominal discomfort — with minimal side effects.\n\nWhether used for traveler’s diarrhea, hepatic encephalopathy, IBS-D, or bacterial overgrowth syndromes, Rifaximin offers targeted, safe, and effective therapy for restoring digestive health and improving overall well-being.",
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"name": "Nicorandil Tablets 5mg",
"description": "Nicorandil Tablets 5 mg is a vasodilatory anti-anginal medication widely prescribed for the management and prevention of angina pectoris (chest pain) associated with coronary artery disease (CAD). Angina results from an imbalance between the heart’s oxygen demand and supply due to restricted blood flow in the coronary arteries. Nicorandil offers a dual mechanism of action — acting both as a nitrate-like vasodilator and a potassium channel opener, making it unique among anti-anginal agents.\n\nBy improving oxygen delivery to the myocardium and reducing cardiac workload, Nicorandil 5 mg Tablets provide effective relief from anginal pain and reduce the frequency and severity of ischemic episodes. It is also beneficial in preventing future attacks, improving exercise tolerance, and enhancing the overall quality of life in patients with chronic stable angina.\n\nComposition\n\nEach tablet contains:\n\nNicorandil IP – 5 mg\n\nExcipients – q.s.\n\nNicorandil tablets are available in film-coated form to ensure stability, easy swallowing, and optimal absorption. They are manufactured in compliance with Good Manufacturing Practices (GMP) standards to ensure safety, purity, and efficacy.\n\nPharmacological Action / Mechanism of Action\n\nNicorandil exhibits a dual mechanism that makes it distinct among anti-anginal drugs:\n\nNitrate-Like Effect:\nNicorandil acts as a nitric oxide (NO) donor. Nitric oxide activates guanylate cyclase, increasing cyclic GMP (cGMP) levels in vascular smooth muscle. This leads to relaxation of blood vessels, particularly veins and large arteries, thereby reducing preload and afterload on the heart. This nitrate-like activity lowers myocardial oxygen demand.\n\nPotassium Channel Opening Effect:\nNicorandil opens ATP-sensitive potassium (KATP) channels in vascular smooth muscle, resulting in arteriolar vasodilation. This increases coronary blood flow and improves oxygen supply to ischemic heart tissues.\n\nTogether, these effects reduce cardiac workload, enhance coronary perfusion, and prevent anginal pain by correcting the oxygen supply-demand mismatch in the heart muscle.\n\nUses and Indications\n\nNicorandil Tablets 5 mg are indicated for the treatment and prevention of angina pectoris in adults, particularly:\n\nChronic Stable Angina:\n\nHelps reduce the frequency and severity of chest pain associated with exertion or emotional stress.\n\nProphylaxis of Angina Attacks:\n\nUsed regularly to prevent anginal episodes, especially in patients with known coronary artery disease.\n\nAdjunct Therapy in Ischemic Heart Disease (IHD):\n\nCan be used alongside beta-blockers, calcium channel blockers, or antiplatelet drugs for enhanced symptom control and long-term protection.\n\nImprovement of Exercise Tolerance:\n\nReduces the likelihood of anginal pain during physical activity, enabling patients to perform daily tasks comfortably.\n\nIn some clinical cases, Nicorandil is also considered for post-myocardial infarction recovery, as it improves coronary perfusion, although this is at the discretion of a cardiologist.\n\nDosage and Administration\n\nRecommended Starting Dose: 5 mg to 10 mg twice daily.\n\nMaintenance Dose: May be increased gradually to 10–20 mg twice daily, depending on clinical response and tolerance.\n\nThe tablets should be swallowed whole with water, preferably at the same times each day.\n\nNicorandil should not be stopped abruptly; dosage tapering is recommended to avoid rebound angina.\n\nAlways follow the dosage instructions provided by the physician.\n\nKey Benefits\n\nDual Mechanism for Comprehensive Relief:\nCombines nitrate-like and potassium channel-opening properties for both arterial and venous dilation, providing superior protection against anginal attacks.\n\nImproves Coronary Blood Flow:\nDilates coronary arteries, increasing oxygen delivery to ischemic myocardial tissues.\n\nReduces Cardiac Workload:\nBy decreasing preload (venous return) and afterload (arterial resistance), Nicorandil minimizes the heart’s oxygen consumption.\n\nRapid Onset of Action:\nNicorandil acts within a short duration, offering quick relief from anginal discomfort.\n\nPrevents Future Angina Episodes:\nRegular use helps maintain steady control of chest pain, improving exercise capacity and quality of life.\n\nCompatible with Other Cardiac Medications:\nCan be safely used alongside antiplatelet agents, beta-blockers, ACE inhibitors, and statins as part of comprehensive cardiac care.\n\nFavorable Safety Profile:\nCompared to nitrates, Nicorandil carries a lower risk of tolerance development, making it suitable for long-term therapy.\n\nEnhances Myocardial Protection:\nNicorandil’s KATP channel activation provides additional cardioprotective effects by improving microvascular blood flow and limiting ischemic damage during stress.\n\nPrecautions and Warnings\n\nAlthough Nicorandil is generally well-tolerated, certain precautions are advised:\n\nHypotension:\nNicorandil may cause a drop in blood pressure due to vasodilation. Caution is advised in patients with hypotension or dehydration.\n\nConcurrent Use with Nitrates:\nShould not be used together with other nitrate medications to avoid severe hypotension.\n\nOral or Gastrointestinal Ulcers:\nRarely, Nicorandil may cause ulcerations in the mouth, intestines, or skin. Treatment should be discontinued if ulceration occurs.\n\nPatients with Low Blood Volume:\nUse cautiously in individuals with hypovolemia or those on diuretics.\n\nDriving and Machinery:\nDizziness or light-headedness may occur; avoid driving until effects are known.\n\nPregnancy and Lactation:\nShould be used only if prescribed by a physician when the potential benefits outweigh the risks.\n\nPossible Side Effects\n\nNicorandil is generally safe but may cause some side effects, particularly at the start of therapy or with higher doses. Common and rare adverse reactions include:\n\nCommon Side Effects:\n\nHeadache (due to vasodilation)\n\nFlushing or warmth sensation\n\nDizziness or light-headedness\n\nNausea or mild stomach upset\n\nFatigue or weakness\n\nLess Common / Rare Side Effects:\n\nHypotension (low blood pressure)\n\nPalpitations or tachycardia\n\nMouth ulcers, anal ulcers, or skin ulceration (uncommon but serious — discontinue if occurs)\n\nRash or allergic reaction\n\nVisual disturbances (rare and usually reversible)\n\nIf any severe reaction or persistent discomfort occurs, medical attention should be sought promptly.\n\nDrug Interactions\n\nAvoid concomitant use with nitrates or phosphodiesterase type-5 inhibitors (e.g., Sildenafil, Tadalafil), as it may cause a dangerous fall in blood pressure.\n\nCaution with antihypertensive drugs or diuretics, which may enhance hypotensive effects.\n\nAlcohol consumption can potentiate dizziness or hypotension and should be limited.\n\nStorage and Handling\n\nStore below 30°C, protected from moisture and direct sunlight.\n\nKeep out of reach of children.\n\nDo not use tablets past the expiry date or if the packaging is damaged.\n\nConclusion\n\nNicorandil Tablets 5 mg offer a modern and effective approach to managing angina pectoris, providing reliable relief through their dual-action mechanism. By combining nitrate-like vasodilation with potassium channel opening, Nicorandil ensures both oxygen supply improvement and reduction of cardiac workload — the cornerstone of angina management.\n\nIt is well-tolerated, fast-acting, and suitable for long-term therapy, making it a preferred choice for patients with chronic stable angina. Regular use under medical supervision helps reduce the frequency of chest pain, improve physical endurance, and enhance the overall quality of life in individuals with coronary artery disease.",
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"name": "Activated Dimethicone IP 50 mg, Magnesium Hydroxide IP 250 mg, Dried Aluminium Hydroxide Gel IP 250 mg & Magnesium Aluminium Silicate Hydrate 50 mg",
"description": "Heartburn MPS Chewable Tablets are a fast-acting, reliable solution for relieving acidity, heartburn, bloating, and gas. Formulated with a combination of antacid and antiflatulent ingredients, Heartburn MPS provides quick and soothing relief from digestive discomfort caused by acid reflux, indigestion, or excessive gas formation.\nComposition (Each Uncoated Chewable Tablet Contains):\nActivated Dimethicone I.P. – 50 mg\nHelps reduce gas and bloating by breaking down gas bubbles in the stomach and intestines.\nMagnesium Hydroxide I.P. – 250 mg\nNeutralizes excess stomach acid and relieves symptoms of acidity and indigestion.\nDried Aluminium Hydroxide Gel I.P. – 250 mg\nProvides rapid acid neutralization and offers a soothing protective coating on the stomach lining.\nMagnesium Aluminium Silicate Hydrate – 50 mg\nActs as a stabilizer and enhances the consistency and effectiveness of the antacid formulation.\nColours:\nMint Tablet: Erythrosine & Ponceau 4R\nOrange Tablet: Sunset Yellow FCF\nMixed Fruit Tablet: Quinoline Yellow WS & Sunset Yellow FCF\nIndications / Uses\nHeartburn MPS Chewable Tablets are indicated for the symptomatic relief of:\nHeartburn and Acidity\nGas and Bloating\nIndigestion and Sour Stomach\nGastric Discomfort and Flatulence\nIt can be taken whenever symptoms of acidity or gas are pronounced, especially after meals.\nMechanism of Action:\nThe combination of Magnesium Hydroxide and Aluminium Hydroxide works by neutralizing stomach acid, thus reducing the burning sensation and discomfort caused by acid reflux.\nMeanwhile, Activated Dimethicone helps relieve bloating and abdominal fullness by dispersing trapped gas. This synergistic action provides quick, long-lasting comfort.\nDosage & Administration:\nRecommended Dose:\n1 to 2 tablets to be chewed ½ to 1 hour after meals or whenever symptoms occur.\nDo not take more than 10 tablets in 24 hours.\nDo not exceed the recommended dose or use the medication for more than two weeks without consulting a physician.\nStorage Instructions:\nStore in a cool, dry, and dark place at a temperature not exceeding 30°C.\nKeep out of reach of children.\nProtect from light and moisture.\nSafety & Precautions:\nKidney Patients: Those with kidney disease should use this medication only under medical supervision.\nLong-Term Use: Prolonged or excessive use may alter electrolyte balance; consult a doctor if symptoms persist.\nPregnancy & Lactation: Use under medical advice.\nPossible Side Effects:\nHeartburn MPS is generally well tolerated. However, some users may experience mild:\nConstipation or Diarrhea\nStomach Cramps\nNausea (rare)\nIf any of these persist or worsen, seek medical attention promptly.\nKey Benefits of Heartburn MPS:\n Instant Relief: Rapid action against acidity and gas discomfort.\n Dual Action Formula: Combines antacid and antiflatulent properties.\n Pleasant Flavors: Available in Mint, Orange, and Mixed Fruit variants.\n Convenient Chewable Form: No water needed; easy to use anywhere.\n Safe & Effective: Manufactured under ISO 9001:2015 & WHO-GMP Certified facilities.\n\nManufacturer Information:\nManufactured by:\nLucent Biotech Limited (Unit-II)\n(An ISO 9001:2015 & WHO GMP certified company)\n165/3, Nalhera-Amanpur, Roorkee-247667,\nDist. Haridwar, Uttarakhand, India.\n\nWhy Choose Heartburn MPS?\nHeartburn MPS stands out as a trusted, fast-acting antacid solution that provides reliable relief from acidity and gas. It’s manufactured under stringent pharmaceutical standards, ensuring quality, safety, and consistent effectiveness in every tablet. Whether it’s a post-meal burning sensation or bloating discomfort, Heartburn MPS delivers gentle yet powerful relief whenever you need it.",
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"description": "RIFAXEMANIA 400 contains Rifaximin 400 mg, a special type of antibiotic that works mainly in the intestines. Unlike many other antibiotics that get absorbed into the bloodstream, rifaximin stays in the digestive tract, making it highly effective for infections and conditions related to the gut while minimizing unwanted effects on the rest of the body.\n\nIt belongs to the rifamycin class of antibiotics and is particularly useful for reducing harmful bacteria in the intestines, restoring gut balance, and improving digestive health. Doctors commonly prescribe it for traveler’s diarrhea, irritable bowel syndrome with diarrhea (IBS-D), and hepatic encephalopathy.\n\nUses of RIFAXEMANIA 400\n\nRIFAXEMANIA 400 is recommended for:\n\nTraveler’s Diarrhea: Effective against non-invasive strains of Escherichia coli.\n\nHepatic Encephalopathy: Helps reduce the recurrence of confusion and related symptoms by lowering the production of toxins such as ammonia in the gut.\n\nIrritable Bowel Syndrome with Diarrhea (IBS-D): Provides relief from abdominal pain, bloating, and frequent loose stools.\n\nSmall Intestinal Bacterial Overgrowth (SIBO): Often prescribed off-label for managing bacterial imbalance in the small intestine.\n\nPrevention of gut-related complications in chronic liver disease.\n\nSide Effects of RIFAXEMANIA 400\n\nMost people tolerate RIFAXEMANIA 400 well because of its local action in the intestines. However, like any medication, some side effects may occur, such as:\n\nNausea or vomiting\n\nHeadache or dizziness\n\nAbdominal pain, bloating, or gas\n\nConstipation or diarrhea (rare)\n\nTiredness or weakness\n\nRash, itching, or other mild allergic reactions\n\nSerious side effects are rare but may include severe diarrhea, persistent abdominal cramps, or signs of allergy such as swelling and breathing difficulty. If these occur, medical help should be sought immediately.\n\nPrecautions Before Using RIFAXEMANIA 400\n\nPatients should keep in mind the following precautions:\n\nDo not use if you are allergic to rifaximin, rifampin, or other rifamycin antibiotics.\n\nAvoid self-medication if you have fever, bloody stools, or severe abdominal pain, as these may indicate a more serious illness.\n\nPatients with advanced liver problems should take the medicine under close medical supervision.\n\nSafety during pregnancy and breastfeeding has not been fully established—consult a doctor before use.\n\nComplete the prescribed course, even if symptoms improve early, to avoid recurrence.\n\nNot meant for viral infections like flu or the common cold.\n\nDrug Interactions\n\nThough rifaximin is minimally absorbed, some drug interactions may occur:\n\nWarfarin or other anticoagulants: May require monitoring of blood clotting.\n\nOther antibiotics: Combining with multiple antibiotics may reduce effectiveness.\n\nCyclosporine and similar drugs: May increase rifaximin levels in the body.\n\nOral contraceptives: Effectiveness may be lowered; consider additional contraception.\n\nAlways share your full list of medications, supplements, or herbal products with your doctor before starting RIFAXEMANIA 400.\n\nConclusion\n\nRIFAXEMANIA 400 (Rifaximin 400 mg) is a trusted and effective choice for managing gastrointestinal conditions like traveler’s diarrhea, IBS-D, hepatic encephalopathy, and bacterial overgrowth syndromes. Its unique property of acting directly in the intestines ensures high effectiveness with fewer systemic side effects.\n\nFor best results, patients should use RIFAXEMANIA 400 only under medical guidance, follow the recommended dosage, and complete the prescribed course.",
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