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"name": "methylprednisolone sodium succinate for injection usp",
"description": "Methylprednisolone Sodium Succinate for Injection USP is a fast-acting corticosteroid administered intravenously or intramuscularly to control severe inflammation, allergic reactions, and autoimmune flare-ups. It works by rapidly suppressing the immune and inflammatory response and is used in hospital or clinical settings for acute conditions such as severe asthma attacks, anaphylaxis, autoimmune disease flares, and spinal cord injury protocols. It is a Schedule H prescription drug administered only under medical supervision.\n\nWhat Is Methylprednisolone Sodium Succinate for Injection USP?\n\nMethylprednisolone Sodium Succinate for Injection USP is a water-soluble, injectable corticosteroid used for rapid control of severe inflammatory, allergic, and autoimmune conditions. It is manufactured to United States Pharmacopeia (USP) standards and is typically administered by a healthcare professional via intravenous (IV) or intramuscular (IM) route when fast, high-potency anti-inflammatory or immunosuppressive action is required — situations where oral steroids act too slowly or oral intake isn't feasible.\n\nHow It Works\n\nMethylprednisolone sodium succinate is a synthetic glucocorticoid that acts rapidly once reconstituted and injected.\n\n\nBinds glucocorticoid receptors – enters cells and binds intracellular receptors that regulate inflammatory gene expression.\nSuppresses inflammatory mediators – reduces production of prostaglandins, leukotrienes, and cytokines responsible for swelling, redness, and pain.\nStabilizes cell membranes – reduces capillary permeability, limiting fluid leakage and tissue swelling at the site of inflammation.\nDampens immune overactivity – suppresses lymphocyte and macrophage activity, calming autoimmune or allergic overreactions.\nDelivers rapid systemic action – because it's water-soluble and given IV/IM, onset of anti-inflammatory effect is significantly faster than oral steroids.\n\n\nClinical Indications\n\nConditionWhy Methylprednisolone Injection Is UsedSevere Allergic Reactions / AnaphylaxisRapidly controls swelling, airway inflammation, and allergic cascadeAcute Asthma Exacerbation / COPD FlareReduces airway inflammation when inhalers alone are insufficientAutoimmune Disease Flares (Lupus, Rheumatoid Arthritis)High-dose pulse therapy to control acute flaresSpinal Cord Injury (acute, under specialist protocol)Used in specific clinical protocols to limit secondary inflammationSevere Dermatologic ReactionsControls widespread inflammatory skin reactionsPost-Transplant / Organ Rejection ManagementUsed as part of immunosuppressive regimens\n\nDosage & Administration\n\nParameterRecommendationTypical Adult Dose10–40 mg IV, may range up to 30 mg/kg in high-dose pulse therapy for specific conditionsRouteIntravenous (IV) injection/infusion or Intramuscular (IM) injectionFrequencyAs directed by the treating physician; often single dose or short tapering courseReconstitutionMust be reconstituted only with the accompanying diluent as per product insert, immediately before useAdministration SettingHospital, clinic, or under direct medical/nursing supervision onlyDurationShort-term acute use unless otherwise directed; long-term use requires specialist monitoring\n\nThis is a Schedule H prescription-only medicine. Dosage must be determined and administered by a qualified healthcare professional.\n\nPrecautions\n\n\nTo be administered only by or under the supervision of a healthcare professional.\nNot for self-administration or home use.\nInform the doctor of any active infections, as corticosteroids can mask symptoms and suppress immune response.\nUse with caution in patients with diabetes, hypertension, peptic ulcer disease, osteoporosis, or psychiatric history.\nAvoid live vaccines during treatment due to immunosuppressive effects.\nPregnant or breastfeeding patients should use only under strict medical guidance.\nAbrupt discontinuation after prolonged use should be avoided; tapering may be required as advised by the physician.\n\n\nPossible Side Effects\n\nMost side effects relate to the drug's systemic corticosteroid action and are monitored by the administering clinician:\n\n\nElevated blood sugar levels\nFluid retention, increased blood pressure\nMood changes, insomnia, or restlessness\nNausea or gastrointestinal discomfort\nIncreased susceptibility to infection\nInjection site reactions\n\n\nSerious side effects requiring immediate medical attention include severe allergic reaction, signs of infection (fever, chills), significant mood or behavioral changes, unusual swelling, or vision disturbances. Because this is administered in a clinical setting, the healthcare team monitors for these actively.\n\nComparison: Methylprednisolone vs. Other Injectable Corticosteroids\n\nDrugRelative PotencyCommon Use CaseRouteMethylprednisolone Sodium SuccinateHighAcute severe inflammation, autoimmune flaresIV/IMHydrocortisone Sodium SuccinateLowerAdrenal insufficiency, milder acute inflammationIV/IMDexamethasone Sodium PhosphateVery HighCerebral edema, severe allergic/inflammatory conditionsIV/IMBetamethasone Sodium PhosphateHighAllergic and inflammatory conditions, fetal lung maturityIV/IMTriamcinolone AcetonideModerate (depot)Localized/intra-articular inflammationIM/Intra-articular\n\nKey Statistics\n\nStatisticData PointSourceOnset of anti-inflammatory action after IV administrationWithin 1–2 hours for measurable effectClinical pharmacology references, USP monographUse in acute severe asthma protocolsRecommended as part of systemic corticosteroid therapy in emergency guidelinesGlobal Initiative for Asthma (GINA) guidelinesHospital use in anaphylaxis managementIncluded as an adjunct in anaphylaxis treatment protocols alongside epinephrineWorld Allergy Organization guidanceHigh-dose pulse therapy applicationUsed in select autoimmune flare protocols under specialist supervisionPublished rheumatology treatment guidelines\n\nExpert Insight\n\n[Insert verified physician or clinical pharmacologist commentary here — Claude has not fabricated a quote. Recommend sourcing a short, attributable statement from a Steris Healthcare medical advisor or a cited clinical guideline before publishing.]\n\nConclusion\n\nMethylprednisolone Sodium Succinate for Injection USP is a high-potency, fast-acting corticosteroid reserved for situations where rapid control of severe inflammation, allergic reaction, or autoimmune flare is essential. Administered only under clinical supervision, it plays a critical role in emergency and hospital-based treatment protocols — from anaphylaxis and acute asthma to autoimmune disease management. As a Schedule H medicine, it must never be self-administered; dosage, route, and duration should always be determined by a qualified physician based on the patient's condition. For pharmacopoeia-grade quality and reliable hospital supply, source this injection through a WHO-GMP certified manufacturer.\n\nPrescription only – consult your doctor.\n\n\nHigh-Ranking FAQs (Google Search & Voice Search Optimized)\n\n1. What is methylprednisolone sodium succinate injection used for?\nIt is used to rapidly control severe inflammation, allergic reactions, and autoimmune flare-ups, such as anaphylaxis, acute asthma attacks, and lupus or rheumatoid arthritis flares. It is administered under medical supervision in hospital or clinical settings.\n\n2. Is methylprednisolone injection a steroid?\nYes, it is a synthetic corticosteroid (glucocorticoid) that works by suppressing inflammatory and immune responses in the body, providing rapid relief in acute, severe conditions.\n\n3. How is methylprednisolone sodium succinate injection given?\nIt is given by a healthcare professional via intravenous (IV) or intramuscular (IM) injection, after being reconstituted with the correct diluent immediately before administration. It is not for self-injection or home use.\n\n4. How fast does methylprednisolone injection start working?\nBecause it is water-soluble and given directly into the bloodstream or muscle, measurable anti-inflammatory effects typically begin within one to two hours of administration.\n\n5. What are the side effects of methylprednisolone injection?\nCommon effects include elevated blood sugar, fluid retention, mood changes, and increased infection risk. These are monitored by the administering healthcare team, and serious reactions are managed promptly in a clinical setting.\n\n6. Is methylprednisolone sodium succinate injection available without a prescription?\nNo. It is a Schedule H prescription-only medicine that must be administered by or under the direct supervision of a qualified healthcare professional.\n\n7. What is the difference between methylprednisolone and dexamethasone injection?\nBoth are injectable corticosteroids, but dexamethasone has a longer duration of action and higher relative potency, while methylprednisolone is often preferred for acute pulse therapy and shorter-acting systemic control. The choice depends on the clinical scenario and physician judgment.\n\n8. Can methylprednisolone injection be used in pregnancy?\nIt may be used in pregnancy only when clearly necessary and under strict medical supervision, as the treating physician will weigh the benefits against potential risks for the specific condition being treated.",
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"name": "paroxetine prolonged release tablets ip",
"description": "Paroxetine Prolonged Release Tablets IP\n\nWhen dealing with mental health conditions such as depression, anxiety, or panic disorders, choosing the right medication is crucial for long-term stability and improved quality of life. Paroxetine Prolonged Release Tablets IP is a widely prescribed medication that offers controlled, sustained relief for individuals struggling with various mood and anxiety-related disorders.\n\nThis detailed buyer-intent guide is designed to help patients, caregivers, and healthcare buyers understand the uses, benefits, working mechanism, dosage, and important precautions associated with Paroxetine Prolonged Release Tablets IP.\n\nWhat is Paroxetine Prolonged Release Tablets IP?\n\nParoxetine Prolonged Release Tablets IP contains paroxetine, a selective serotonin reuptake inhibitor (SSRI). It is specifically formulated in a prolonged-release (controlled-release) form, which allows the medication to be released gradually in the body over time.\n\nThis ensures:\n\nStable blood levels of the drug\nReduced dosing frequency\nImproved patient compliance\nFewer fluctuations in therapeutic effect\n\nIt is commonly prescribed for managing a range of psychiatric conditions, including depression and anxiety disorders.\n\nHow Does Paroxetine Prolonged Release Tablets IP Work?\n\nParoxetine works by increasing the levels of serotonin, a neurotransmitter in the brain that plays a key role in mood regulation, emotional balance, and mental well-being.\n\nMechanism of Action:\nBlocks the reabsorption (reuptake) of serotonin in the brain\nEnhances serotonin availability between nerve cells\nImproves communication between neurons\nStabilizes mood and reduces anxiety symptoms\nWhy Prolonged Release Matters:\n\nThe prolonged-release formulation ensures a steady release of medication throughout the day, minimizing side effects and maintaining consistent symptom control.\n\nKey Benefits of Paroxetine Prolonged Release Tablets IP\n1. Effective Treatment for Depression\n\nHelps reduce persistent sadness, low energy, and loss of interest in daily activities.\n\n2. Controls Anxiety Disorders\n\nHighly effective in treating generalized anxiety disorder (GAD), social anxiety, and panic disorder.\n\n3. Improves Emotional Stability\n\nSupports better mood regulation and reduces emotional fluctuations.\n\n4. Once-Daily Convenience\n\nThe prolonged-release formula allows for easy once-daily dosing.\n\n5. Better Tolerability\n\nGradual drug release reduces the risk of sudden side effects compared to immediate-release formulations.\n\nCommon Uses of Paroxetine Prolonged Release Tablets IP\n\nThis medication is prescribed for:\n\nMajor depressive disorder (MDD)\nGeneralized anxiety disorder (GAD)\nPanic disorder\nSocial anxiety disorder\nObsessive-compulsive disorder (OCD)\nPost-traumatic stress disorder (PTSD)\n\nIt is also sometimes used for other conditions based on a doctor’s recommendation.\n\nWho Should Consider Buying Paroxetine Prolonged Release Tablets IP?\n\nThis medication may be suitable for:\n\nIndividuals diagnosed with depression or anxiety disorders\nPatients needing long-term psychiatric management\nThose who prefer once-daily medication for better compliance\nIndividuals who experience side effects with immediate-release SSRIs\n\nImportant: This medication should only be used under a doctor’s prescription and supervision.\n\nDosage and Administration\n\nThe dosage of Paroxetine Prolonged Release Tablets IP depends on the condition being treated and the patient’s response.\n\nGeneral Guidelines:\nTypically taken once daily, usually in the morning\nSwallow the tablet whole with water\nDo not crush, chew, or break the tablet\nDosage Tips:\nStart with a lower dose and increase gradually as advised\nTake the medicine at the same time every day\nDo not skip doses or stop suddenly\nPossible Side Effects\n\nLike all medications, Paroxetine Prolonged Release Tablets IP may cause side effects.\n\nCommon Side Effects:\nNausea\nDrowsiness or fatigue\nDry mouth\nDizziness\nSweating\nLess Common but Serious Side Effects:\nSuicidal thoughts (especially in young adults)\nSevere mood changes\nSerotonin syndrome (rare but serious)\nSexual dysfunction\nWeight changes\n\nIf you experience severe or unusual symptoms, seek medical help immediately.\n\nPrecautions and Warnings\n\nBefore starting this medication, consider the following:\n\nMedical Conditions:\nInform your doctor if you have liver or kidney disease\nPatients with a history of seizures should use caution\nAvoid use in individuals with bipolar disorder without supervision\nPregnancy and Breastfeeding:\nUse only if prescribed\nDiscuss potential risks and benefits with your doctor\nDrug Interactions:\n\nParoxetine may interact with:\n\nMonoamine oxidase inhibitors (MAOIs)\nBlood thinners\nOther antidepressants\nAnti-anxiety medications\n\nAlways inform your healthcare provider about all medications and supplements you are taking.\n\nStorage Instructions\n\nTo maintain effectiveness:\n\nStore in a cool, dry place\nKeep away from direct sunlight\nMaintain temperature below 25°C\nKeep out of reach of children\nBuying Guide: What to Check Before Purchase\n\nWhen purchasing Paroxetine Prolonged Release Tablets IP, ensure the following:\n\nIt is prescribed by a qualified doctor\nThe product is from a trusted pharmaceutical brand\nPackaging is sealed and undamaged\nExpiry date is valid\nPurchased from a licensed pharmacy\n\nFor distributors or bulk buyers, sourcing from reliable manufacturers ensures quality and consistency.\n\nWhy Choose Paroxetine Prolonged Release Tablets IP?\n\nThis medication stands out because of the following:\n\nProven effectiveness in mental health treatment\nControlled-release technology for consistent results\nImproved patient compliance with once-daily dosing\nReduced side effects compared to immediate-release forms\nWidely trusted by healthcare professionals\n\nFor individuals seeking reliable and long-term management of depression and anxiety, this medication is a strong and dependable choice.\n\nFrequently Asked Questions (FAQs)\n1. How long does it take to work?\n\nIt may take 2–4 weeks to notice improvement, with full benefits appearing after several weeks.\n\n2. Can I stop taking it once I feel better?\n\nNo, stopping suddenly can cause withdrawal symptoms. Always consult your doctor.\n\n3. Is it addictive?\n\nNo, but it should be taken as prescribed to avoid dependency-like withdrawal symptoms.\n\n4. Can I take it at night?\n\nIt is usually taken in the morning, but your doctor may adjust timing based on your condition.\n\n5. Does it affect sleep?\n\nIt may cause drowsiness or insomnia in some individuals.\n\nLifestyle Tips for Better Results\n\nTo enhance the effectiveness of Paroxetine:\n\nMaintain a regular sleep schedule\nPractice stress management techniques (yoga, meditation)\nEat a balanced diet\nAvoid alcohol and recreational drugs\nStay physically active\nConclusion\n\nParoxetine Prolonged Release Tablets IP is a highly effective and well-established medication for managing depression, anxiety, and other mental health conditions. Its prolonged-release formulation ensures steady symptom control, improved tolerability, and better patient compliance.\n\nFor best results, always use this medication under medical supervision, follow the prescribed dosage, and combine it with a healthy lifestyle. With the right approach, it can significantly improve emotional well-being and overall quality of life.",
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"name": "ambroxol + guaifenesin + terbutaline",
"description": "RAPIDKOF XT is a highly effective combination medication that contains Ambroxol, Guaifenesin, and Terbutaline, specifically formulated to provide relief from respiratory tract disorders such as cough, congestion, and bronchial asthma. This triple-action formulation is widely used for managing productive cough, thick mucus accumulation, and airway constriction, offering a comprehensive approach to respiratory care.\n\nThe synergistic combination of a mucolytic, an expectorant, and a bronchodilator in RAPIDKOF XT ensures effective clearing of mucus, relaxation of bronchial muscles, and easier breathing. This makes it an ideal choice for patients suffering from chronic bronchitis, asthma exacerbations, and respiratory infections with productive cough. By targeting multiple pathways involved in respiratory distress, RAPIDKOF XT provides faster symptomatic relief and supports better lung function.\n\nIt is essential to use RAPIDKOF XT under medical supervision, as proper dosage and duration are crucial for safe and effective treatment.\n\nComposition\n\nEach RAPIDKOF XT tablet or syrup (depending on the formulation) contains:\n\nAmbroxol – a mucolytic agent that thins and loosens mucus in the airways.\n\nGuaifenesin—an expectorant that promotes the removal of mucus from the respiratory tract.\n\nTerbutaline is a bronchodilator that relaxes the smooth muscles of the airways, improving airflow.\n\nThis combination provides multi-level relief by addressing mucus accumulation, airway constriction, and cough simultaneously.\n\nHow RAPIDKOF XT Works\n\nThe effectiveness of RAPIDKOF XT lies in its triple-action mechanism:\n\nAmbroxol\n\nAmbroxol works as a mucolytic agent by breaking down the structure of thick, sticky mucus in the respiratory tract. This action makes it easier for patients to cough up phlegm, reducing airway obstruction and improving oxygen exchange. Ambroxol also enhances the protective function of respiratory mucosa by stimulating surfactant production.\n\nGuaifenesin\n\nGuaifenesin is an expectorant that promotes the expulsion of mucus from the lungs and bronchi. It increases the volume of secretions while reducing their viscosity, which helps in clearing the airways and alleviating productive cough.\n\nTerbutaline\n\nTerbutaline is a selective beta-2 adrenergic agonist, a type of bronchodilator. It relaxes the smooth muscles in the airways, leading to widening of the bronchial passages. This action reduces wheezing, shortness of breath, and chest tightness associated with asthma and other obstructive airway conditions.\n\nUses of RAPIDKOF XT\n\nRAPIDKOF XT is indicated for various respiratory conditions where mucus accumulation, cough, and airway constriction coexist.\n\n1. Productive Cough\n\nIt helps patients with thick and sticky phlegm by thinning mucus, making it easier to expel through coughing.\n\n2. Chronic and Acute Bronchitis\n\nRAPIDKOF XT provides relief from inflammation, mucus buildup, and bronchial spasm, improving breathing and reducing discomfort.\n\n3. Asthma and Bronchospasm\n\nTerbutaline in the formulation helps relax constricted airways, making it suitable for patients with asthmatic bronchitis or mild to moderate asthma exacerbations.\n\n4. Respiratory Tract Infections\n\nThe combination aids recovery from viral or bacterial respiratory infections by facilitating mucus clearance and alleviating associated cough and congestion.\n\n5. Other Obstructive Pulmonary Conditions\n\nRAPIDKOF XT may be prescribed in conditions such as chronic obstructive pulmonary disease (COPD), where airway obstruction and mucus accumulation are major issues.\n\nKey Benefits of RAPIDKOF XT\n\nRAPIDKOF XT offers multiple therapeutic benefits due to the synergistic action of its components:\n\nEffective Mucus Clearance\n\nAmbroxol and guaifenesin work together to loosen and expel mucus, improving airway patency and reducing cough severity.\n\nRelief from Bronchospasm\n\nTerbutaline relaxes airway muscles, helping patients breathe more easily and reducing wheezing, tightness, and shortness of breath.\n\nSymptomatic Relief from Cough\n\nThe combination reduces both productive and irritating cough, enhancing comfort and improving sleep quality.\n\nSupport for Respiratory Recovery\n\nBy facilitating mucus clearance and improving airflow, RAPIDKOF XT supports faster recovery from infections and inflammatory airway conditions.\n\nImproved Oxygenation and Energy\n\nBetter airway clearance and bronchodilation allow improved oxygen intake, which enhances overall energy levels and reduces fatigue associated with respiratory distress.\n\nSuitable for Both Acute and Chronic Conditions\n\nRAPIDKOF XT can be used in both short-term respiratory infections and long-term management of chronic bronchial conditions, depending on a doctor’s guidance.\n\nRecommended Dosage and Administration\n\nThe dosage of RAPIDKOF XT should always follow medical prescription, and the form of administration (tablet or syrup) may vary depending on the patient’s age and severity of symptoms.\n\nAdults: Typically 1 tablet or a measured dose of syrup 2–3 times daily.\n\nChildren: Dosage should be adjusted according to age and weight as advised by a doctor.\n\nTake with water after meals to reduce the risk of stomach upset.\n\nContinue the full course as prescribed, even if symptoms improve.\n\nPossible Side Effects of RAPIDKOF XT\n\nMost patients tolerate RAPIDKOF XT well. However, some individuals may experience mild side effects, and serious reactions, though rare, are possible.\n\nCommon Side Effects\n\nMild nausea or stomach upset\n\nHeadache or dizziness\n\nTremors (from terbutaline)\n\nPalpitations or increased heart rate in sensitive individuals\n\nLess Common Side Effects\n\nDry mouth or throat irritation\n\nMild rash or skin itching\n\nTemporary restlessness or insomnia\n\nRare but Serious Side Effects\n\nSevere allergic reactions (swelling, difficulty breathing)\n\nSevere tachycardia or irregular heartbeat\n\nLow potassium levels (with prolonged terbutaline use)\n\nSevere gastrointestinal discomfort\n\nPatients experiencing serious side effects should seek immediate medical attention.\n\nPrecautions and Safety Information\n\nConsult your doctor if you have heart disease, high blood pressure, diabetes, or thyroid disorders before taking RAPIDKOF XT.\n\nAvoid using other stimulants or bronchodilators without medical guidance.\n\nPregnant or breastfeeding women should use the medication only under strict medical supervision.\n\nInform your doctor about all medications being taken to avoid drug interactions.\n\nUse with caution in elderly patients due to increased sensitivity to terbutaline.\n\nStorage Instructions\n\nStore in a cool, dry place below 30°C.\n\nKeep away from direct sunlight, heat, and moisture.\n\nKeep out of reach of children.\n\nDo not use after the expiration date on the packaging.\n\nConclusion\nRAPIDKOF XT is a triple-action respiratory medication that combines Ambroxol, Guaifenesin, and Terbutaline to provide comprehensive relief from cough, mucus accumulation, and bronchial constriction. Its unique formulation ensures faster symptomatic relief, improved airway clearance, and enhanced respiratory function.",
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"name": "Acamprosate Gastro Resistant 666mg",
"description": "ACAMPURE 666 is a prescription medication containing Acamprosate Gastro-Resistant 666 mg, a medicine specifically designed to support individuals recovering from alcohol dependence. It is commonly used as part of a comprehensive treatment program that includes counseling, behavioral therapy, and lifestyle changes to help individuals maintain long-term sobriety.\n\nAlcohol dependence is a chronic condition that affects both the brain and behavior. Even after stopping alcohol consumption, many individuals continue to experience intense cravings and psychological discomfort that may lead to relapse. ACAMPURE 666 works by helping restore the natural chemical balance in the brain that becomes disrupted due to prolonged alcohol use.\n\nThe gastro-resistant formulation ensures that the medication passes through the stomach without breaking down and dissolves in the intestine, which improves absorption and reduces potential stomach irritation. This formulation makes ACAMPURE 666 an effective and well-tolerated option for individuals seeking support during alcohol recovery.\n\nACAMPURE 666 should always be used under the supervision of a healthcare professional and is most effective when combined with proper psychological and social support.\n\nComposition\n\nActive Ingredient: Acamprosate Calcium equivalent to Acamprosate 666 mg\n\nDosage Form: Gastro-resistant oral tablet\n\nBrand Name: ACAMPURE 666\n\nEach tablet of ACAMPURE 666 is carefully formulated to deliver a controlled release of Acamprosate in the intestinal tract, helping maintain consistent therapeutic levels in the body.\n\nHow ACAMPURE 666 Works\n\nLong-term alcohol consumption disrupts the balance of certain neurotransmitters in the brain, particularly glutamate and GABA. These chemicals regulate brain activity and mood. When a person stops drinking alcohol, the imbalance may cause symptoms such as anxiety, irritability, insomnia, and strong cravings for alcohol.\n\nACAMPURE 666 works by stabilizing the chemical signaling in the brain. It reduces excessive stimulation caused by glutamate activity and helps normalize brain function after alcohol withdrawal. By restoring this balance, the medication helps reduce cravings and supports abstinence from alcohol.\n\nUnlike some other treatments for alcohol dependence, ACAMPURE 666 does not cause unpleasant reactions if alcohol is consumed. Instead, it works by helping the brain maintain a more stable state that reduces the urge to drink.\n\nUses of ACAMPURE 666\n\nACAMPURE 666 is primarily prescribed to support individuals who have already stopped drinking alcohol and want to maintain long-term sobriety.\n\n1. Maintenance of Alcohol Abstinence\n\nThe primary use of ACAMPURE 666 is to help individuals remain alcohol-free after detoxification. It reduces the mental and emotional urge to drink and strengthens recovery efforts.\n\n2. Support During Alcohol Rehabilitation Programs\n\nACAMPURE 666 is often included as part of structured alcohol rehabilitation programs that include therapy, counseling, and social support.\n\n3. Reduction of Alcohol Cravings\n\nMany individuals in recovery experience persistent cravings that can trigger relapse. ACAMPURE 666 helps reduce these cravings by stabilizing brain chemistry.\n\n4. Long-Term Recovery Support\n\nAlcohol addiction is a long-term condition that may require extended treatment. ACAMPURE 666 can be used for several months or longer as recommended by a healthcare professional to maintain recovery progress.\n\nKey Benefits of ACAMPURE 666\n\nACAMPURE 666 provides several important benefits for individuals recovering from alcohol dependence.\n\nHelps Maintain Sobriety\n\nOne of the most important benefits of ACAMPURE 666 is its ability to help individuals remain alcohol-free. It supports the brain during the recovery process and reduces the risk of relapse.\n\nReduces Alcohol Cravings\n\nThe medication works directly on brain neurotransmitters to reduce the intense cravings that often occur after quitting alcohol.\n\nSupports Brain Recovery\n\nProlonged alcohol consumption affects brain function. ACAMPURE 666 helps restore the natural chemical balance, allowing the brain to gradually recover.\n\nNon-Addictive Treatment Option\n\nACAMPURE 666 is not addictive and does not produce dependency, making it a safe option for long-term use in alcohol recovery programs.\n\nGastro-Resistant Formulation\n\nThe gastro-resistant coating protects the tablet from stomach acid and ensures that the medication is released in the intestine. This improves absorption and reduces stomach irritation.\n\nCompatible with Therapy Programs\n\nACAMPURE 666 works well alongside counseling, behavioral therapy, and support groups, helping patients achieve better recovery outcomes.\n\nRecommended Dosage and Administration\n\nACAMPURE 666 should be taken exactly as prescribed by a healthcare professional.\n\nTypical usage guidelines include:\n\nThe medication is usually taken three times daily.\n\nTablets should be swallowed whole with water.\n\nDo not crush or chew the gastro-resistant tablets.\n\nIt can be taken with or without food.\n\nTreatment often begins after the patient has stopped drinking alcohol.\n\nThe exact dosage and duration of treatment may vary depending on the patient's medical condition and the doctor’s recommendation.\n\nPossible Side Effects of ACAMPURE 666\n\nLike all medications, ACAMPURE 666 may cause side effects in some individuals. Most side effects are mild and tend to improve as the body adjusts to the medication.\n\nCommon Side Effects\n\nDiarrhea\n\nNausea\n\nStomach discomfort\n\nLoss of appetite\n\nHeadache\n\nDizziness\n\nThese symptoms are usually temporary and may disappear with continued use.\n\nLess Common Side Effects\n\nSome individuals may experience:\n\nDry mouth\n\nFatigue\n\nAnxiety or mood changes\n\nSkin rash or itching\n\nDifficulty sleeping\n\nRare but Serious Side Effects\n\nIn rare cases, serious side effects may occur, such as:\n\nSevere allergic reactions\n\nDepression or suicidal thoughts\n\nSignificant changes in mood or behavior\n\nIf any severe symptoms occur, medical attention should be sought immediately.\n\nPrecautions and Safety Information\n\nBefore taking ACAMPURE 666, patients should discuss their medical history and current medications with their healthcare provider.\n\nImportant precautions include:\n\nInform the doctor if you have kidney disease, as dosage adjustments may be required.\n\nACAMPURE 666 should not be used by individuals with severe kidney impairment.\n\nPregnant or breastfeeding women should consult their doctor before using this medication.\n\nPatients should continue participating in counseling or therapy while taking the medication.\n\nAvoid skipping doses to maintain consistent effectiveness.\n\nIt is important to note that ACAMPURE 666 works best for individuals who are committed to remaining alcohol-free.\n\nStorage Instructions\n\nTo maintain the quality and effectiveness of ACAMPURE 666:\n\nStore the tablets at room temperature.\n\nKeep away from direct sunlight and moisture.\n\nStore in the original packaging until use.\n\nKeep out of reach of children.\n\nDo not use the medication after the expiration date mentioned on the packaging.\n\nConclusion\n\nACAMPURE 666 (Acamprosate Gastro-Resistant 666 mg) is an effective medication designed to support individuals recovering from alcohol dependence. By helping restore the natural balance of brain chemicals disrupted by long-term alcohol use, it reduces cravings and supports long-term abstinence.\n\nThe gastro-resistant formulation enhances absorption and minimizes stomach irritation, making it a reliable treatment option in alcohol recovery programs. When combined with counseling, behavioral therapy, and strong social support, ACAMPURE 666 can significantly improve the chances of maintaining sobriety.",
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"name": "Trazodone Hydrochloride 25 mg",
"description": "Mental health is just as important as physical health, yet it is often overlooked. Sleep disturbances, anxiety, and depression can deeply affect daily functioning, relationships, and overall quality of life. TORRANE 25, formulated with Trazodone Hydrochloride 25 mg, is a prescription medication designed to help individuals manage symptoms of depression and associated sleep disturbances.\n\nTORRANE 25 works by restoring the balance of certain neurotransmitters in the brain, particularly serotonin. By improving mood and promoting restful sleep, it supports emotional stability and mental well-being. This medication is often prescribed in low doses to help with insomnia related to depression or anxiety disorders.\n\nProduct Description\n\nTORRANE 25 contains Trazodone Hydrochloride 25 mg, an antidepressant that belongs to the class of serotonin antagonist and reuptake inhibitors (SARIs). Unlike traditional antidepressants that focus solely on serotonin reuptake inhibition, trazodone has a dual mechanism of action that enhances serotonin activity while also blocking certain serotonin receptors.\n\nThis unique action not only helps improve mood but also has calming and sedative properties, making it beneficial for patients who experience difficulty sleeping. The 25 mg dosage is often used as a starting dose or for patients who require lower strength for sleep-related issues.\n\nTORRANE 25 is formulated in tablet form for oral administration and is typically prescribed under medical supervision.\n\nHow TORRANE 25 Works\n\nThe effectiveness of TORRANE 25 lies in its influence on brain chemistry. Depression and anxiety disorders are often associated with imbalances in neurotransmitters, particularly serotonin.\n\nMechanism of Action\n\nSerotonin Reuptake Inhibition\nTrazodone prevents the reabsorption (reuptake) of serotonin into nerve cells, increasing its availability in the brain.\n\nSerotonin Receptor Antagonism\nIt blocks specific serotonin receptors that are linked to anxiety and sleep disturbances, providing calming effects.\n\nMild Sedative Effect\nThe medication has antihistaminic properties that promote relaxation and improve sleep quality.\n\nMood Stabilization\nBy enhancing serotonin activity, TORRANE 25 helps improve mood, reduce feelings of sadness, and enhance emotional balance.\n\nThis combined mechanism makes it particularly useful for patients with depression accompanied by insomnia.\n\nUses of TORRANE 25\n\nTORRANE 25 is commonly prescribed for:\n\nMajor depressive disorder (MDD)\n\nDepression associated with anxiety\n\nInsomnia related to depression\n\nSleep disturbances\n\nAnxiety-related symptoms\n\nWhile primarily indicated for depression, it is frequently used in lower doses to manage sleep problems due to its sedative properties.\n\nKey Benefits of TORRANE 25\n1. Improves Mood\n\nBy increasing serotonin levels, it helps reduce symptoms of depression such as sadness, hopelessness, and irritability.\n\n2. Promotes Restful Sleep\n\nIts calming effect makes it beneficial for individuals suffering from insomnia.\n\n3. Reduces Anxiety\n\nBlocking certain serotonin receptors can help alleviate anxiety symptoms.\n\n4. Enhances Daily Functioning\n\nImproved sleep and mood contribute to better focus, productivity, and overall quality of life.\n\n5. Lower Risk of Dependence\n\nUnlike some sleep medications, trazodone has a lower risk of dependency when used as prescribed.\n\nDosage and Administration\n\nThe dosage of Trazodone Hydrochloride 25 mg depends on the condition being treated and the patient’s medical history.\n\nFor sleep disturbances: 25–50 mg at bedtime.\n\nFor depression: Higher doses may be prescribed gradually under supervision.\n\nTablets should be taken after meals to reduce the risk of stomach upset. It is important to follow the physician’s instructions carefully and not adjust the dose without consultation.\n\nSide Effects of TORRANE 25\n\nLike all medications, TORRANE 25 may cause side effects. Most are mild and manageable, especially during the initial phase of treatment.\n\nCommon Side Effects\n\nDrowsiness\n\nDizziness\n\nDry mouth\n\nHeadache\n\nNausea\n\nBlurred vision\n\nConstipation\n\nThese side effects usually subside as the body adjusts to the medication.\n\nSerious Side Effects\n\nAlthough rare, serious side effects may occur:\n\nIrregular heartbeat\n\nSevere dizziness or fainting\n\nMood changes or worsening depression\n\nSuicidal thoughts (particularly in young adults)\n\nPriapism (prolonged painful erection in males)\n\nImmediate medical attention is required if any severe symptoms appear.\n\nPrecautions and Warnings\n\nInform your doctor about any history of heart disease, liver problems, or bipolar disorder.\n\nAvoid alcohol, as it may increase drowsiness.\n\nDo not operate heavy machinery until you know how the medication affects you.\n\nPregnant or breastfeeding women should consult their doctor before use.\n\nAbrupt discontinuation may cause withdrawal symptoms; tapering under medical supervision is recommended.\n\nWho Should Use TORRANE 25?\n\nTORRANE 25 is suitable for adults diagnosed with depression, anxiety-related disorders, or sleep disturbances. It is particularly helpful for individuals who struggle with both mood issues and insomnia.\n\nHowever, it should only be taken under prescription and regular follow-up with a healthcare professional.\n\nStorage Instructions\n\nStore at room temperature below 25°C.\n\nKeep away from moisture and direct sunlight.\n\nKeep out of reach of children.\nConclusion\nTORRANE 25 (Trazodone Hydrochloride 25 mg) is a versatile and effective medication used to manage depression and sleep disturbances. Its unique mechanism of action enhances serotonin levels while promoting relaxation, making it particularly beneficial for individuals experiencing mood disorders accompanied by insomnia.",
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"name": "Baclofen Sustained Release 30 mg",
"description": "BACLOFINE SR 30: Comprehensive Product Guide\nProduct Overview\nBACLOFINE SR 30 is an advanced pharmaceutical formulation containing Baclofen 30 mg in a sustained-release delivery system. This prescription medication represents a significant advancement in the management of muscle spasticity and related neuromuscular conditions. The sustained-release technology ensures consistent therapeutic effects throughout the day, providing patients with improved symptom control and enhanced quality of life.\nBaclofen, the active pharmaceutical ingredient in BACLOFINE SR 30, belongs to a class of medications known as skeletal muscle relaxants and antispasmodic agents. The SR (Sustained Release) formulation is specifically engineered to release the medication gradually over an extended period, maintaining steady blood levels and reducing the frequency of dosing compared to conventional immediate-release formulations.\nMechanism of Action and Therapeutic Use\nBACLOFINE SR 30 works by acting on the central nervous system, specifically targeting GABA-B receptors in the spinal cord and brain. GABA (gamma-aminobutyric acid) is the primary inhibitory neurotransmitter in the nervous system. By stimulating these receptors, Baclofen reduces the excessive nerve signals that cause muscles to contract involuntarily, thereby alleviating spasticity and associated discomfort.\nThe sustained-release technology incorporated in BACLOFINE SR 30 utilizes advanced polymer-based matrices that control the rate at which the active ingredient is released into the bloodstream. This innovative approach ensures that patients receive consistent therapeutic coverage for up to 12-24 hours from a single dose, eliminating the peaks and troughs associated with immediate-release formulations.\nPrimary Indications\nBACLOFINE SR 30 is primarily prescribed for managing muscle spasticity associated with various neurological conditions including multiple sclerosis, spinal cord injuries, cerebral palsy, stroke, brain injuries, and other conditions affecting the central nervous system. The medication is particularly beneficial for patients experiencing painful muscle spasms, stiffness, and involuntary muscle contractions that interfere with daily activities, mobility, and rehabilitation efforts.\nKey Benefits of BACLOFINE SR 30\nExtended Duration of Action\nThe most significant advantage of BACLOFINE SR 30 is its sustained-release formulation, which provides prolonged therapeutic effects. Patients typically require only one or two doses per day, compared to three or four doses with conventional formulations. This extended duration improves medication adherence and provides more consistent symptom control throughout the day and night.\nImproved Symptom Management\nBy maintaining steady blood levels of Baclofen, BACLOFINE SR 30 delivers superior control of muscle spasticity with fewer fluctuations in symptom relief. Patients experience reduced muscle stiffness, decreased frequency and severity of muscle spasms, improved range of motion, and enhanced ability to participate in physical therapy and rehabilitation programs.\nEnhanced Quality of Life\nThe consistent therapeutic effects of BACLOFINE SR 30 translate into meaningful improvements in daily functioning. Patients often report better sleep quality due to reduced nighttime spasms, improved mobility and independence in performing daily activities, reduced pain and discomfort associated with muscle spasticity, and greater participation in social and recreational activities.\nReduced Dosing Frequency\nThe sustained-release technology means fewer doses throughout the day, which simplifies medication regimens and improves compliance, particularly for patients managing multiple medications. This convenience factor is especially valuable for individuals with cognitive impairments or those who require caregiver assistance with medication administration.\nSmoother Therapeutic Response\nUnlike immediate-release formulations that can cause pronounced peaks in drug levels, BACLOFINE SR 30 provides a more gradual and sustained therapeutic effect. This results in reduced risk of dose-related side effects, more stable muscle relaxation throughout the dosing interval, and minimized breakthrough spasticity between doses.\nPotential Side Effects and Considerations\nWhile BACLOFINE SR 30 is generally well-tolerated, patients should be aware of potential side effects. It's important to note that not everyone experiences these effects, and many side effects diminish as the body adjusts to the medication.\nCommon Side Effects\nThe most frequently reported side effects include drowsiness and sedation, which typically occur during initial therapy or dose adjustments. Patients may also experience dizziness, fatigue, weakness, headache, nausea, and constipation. These effects are usually mild to moderate and often resolve within the first few weeks of treatment.\nCentral Nervous System Effects\nSome patients may experience confusion, particularly elderly individuals, difficulty concentrating, insomnia or sleep disturbances, and mood changes. These effects should be monitored and reported to healthcare providers if they persist or worsen.\nCardiovascular and Other Effects\nOccasional side effects may include hypotension (low blood pressure), urinary frequency or retention, dry mouth, and muscle weakness beyond the intended therapeutic effect.\nSerious Considerations\nPatients should seek immediate medical attention if they experience severe allergic reactions, hallucinations or severe confusion, difficulty breathing, severe muscle weakness affecting breathing or swallowing, or signs of overdose including extreme drowsiness, respiratory depression, or seizures.\nImportant Warnings\nBACLOFINE SR 30 should never be discontinued abruptly without medical supervision, as sudden withdrawal can lead to serious complications including seizures, hallucinations, increased spasticity, and other potentially life-threatening symptoms. Dose reduction must be gradual and carefully supervised by a healthcare provider.\nThe medication may cause drowsiness and impair mental alertness, so patients should avoid driving, operating machinery, or engaging in activities requiring full alertness until they understand how the medication affects them. Alcohol and other central nervous system depressants should be avoided or used with extreme caution, as they can potentiate the sedative effects of Baclofen.\nDosage and Administration Guidelines\nBACLOFINE SR 30 should be taken exactly as prescribed by a healthcare provider. The tablets should be swallowed whole and not crushed, chewed, or broken, as this would compromise the sustained-release mechanism and potentially lead to dose dumping. The medication can be taken with or without food, though taking it with food may help reduce gastrointestinal side effects.\nDosage is highly individualized based on the patient's condition, response to treatment, and tolerance. Healthcare providers typically initiate therapy at lower doses and gradually titrate upward to achieve optimal therapeutic effects while minimizing side effects.\nConclusion\nBACLOFINE SR 30 represents a sophisticated therapeutic option for individuals struggling with muscle spasticity and related neuromuscular conditions. The sustained-release formulation offers distinct advantages over conventional immediate-release preparations, including extended duration of action, improved symptom control, reduced dosing frequency, and enhanced patient convenience and compliance.",
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"name": "Trazodone Hydrochloride 50 mg",
"description": "TORRANE 50 is a pharmaceutical formulation containing Trazodone Hydrochloride 50 mg as its active ingredient. This medication belongs to the class of serotonin antagonist and reuptake inhibitors (SARIs), primarily prescribed for the management of major depressive disorder and associated sleep disturbances. TORRANE 50 represents a trusted therapeutic option that has been helping individuals regain emotional balance and improve their quality of life for decades. The medication works by modulating serotonin levels in the brain, offering relief from depression while simultaneously addressing insomnia that often accompanies mood disorders.\nUnderstanding Trazodone Hydrochloride\nTrazodone Hydrochloride is a unique antidepressant that distinguishes itself from other medications in its class through its dual-action mechanism. Unlike traditional selective serotonin reuptake inhibitors (SSRIs), TORRANE 50 not only helps restore serotonin balance but also possesses sedative properties that make it particularly valuable for patients struggling with both depression and sleep difficulties. The 50mg dosage represents a common starting point for treatment, allowing healthcare providers to carefully titrate the dose according to individual patient needs and responses.\nPrimary Uses and Applications\nTORRANE 50 serves multiple therapeutic purposes, making it a versatile option in psychiatric and general medical practice. The primary indication for this medication is major depressive disorder, where it helps alleviate symptoms such as persistent sadness, loss of interest in daily activities, feelings of worthlessness, and difficulty concentrating. Beyond its antidepressant properties, TORRANE 50 has gained significant recognition for its effectiveness in treating insomnia, particularly when sleep disturbances are related to depression or anxiety.\nHealthcare providers may also prescribe TORRANE 50 off-label for various conditions including generalized anxiety disorder, panic disorder, and chronic pain conditions where sleep disturbance is a prominent feature. The medication's ability to improve sleep architecture without the dependency risks associated with traditional benzodiazepines makes it an attractive option for long-term management of sleep-related issues.\nKey Benefits and Therapeutic Advantages\nThe benefits of TORRANE 50 extend far beyond simple symptom management, offering patients a comprehensive approach to mental health wellness. One of the most significant advantages is its dual-action profile, addressing both mood and sleep disturbances simultaneously. This is particularly beneficial because depression and insomnia often exist in a cyclical relationship, where each condition exacerbates the other.\nTORRANE 50 demonstrates a relatively favorable side effect profile compared to some other antidepressants, with lower risks of sexual dysfunction, which is a common concern with many SSRI medications. This makes it an excellent alternative for patients who have experienced these troublesome side effects with other antidepressants. Additionally, the medication is not associated with significant weight gain in most patients, addressing another common concern that can affect medication adherence.\nThe sedative properties of TORRANE 50, while beneficial for sleep, are dose-dependent, allowing physicians to customize treatment strategies. At lower doses, the medication primarily promotes sleep, while higher doses deliver more pronounced antidepressant effects. This flexibility enables healthcare providers to tailor treatment to individual patient needs effectively.\nAnother notable benefit is that TORRANE 50 has a relatively low potential for abuse compared to benzodiazepines and other sleep medications, making it safer for long-term use in appropriate patients. The medication also begins to improve sleep quality relatively quickly, often within the first week of treatment, though the full antidepressant effects may take several weeks to manifest fully.\nPotential Side Effects and Considerations\nLike all medications, TORRANE 50 may cause side effects, though not everyone experiences them. Understanding these potential effects helps patients and healthcare providers work together to optimize treatment outcomes. Common side effects include drowsiness and dizziness, particularly when starting the medication or increasing the dose. These effects are often most pronounced in the first few days of treatment and typically diminish as the body adjusts to the medication.\nSome patients may experience dry mouth, blurred vision, constipation, or headaches. These anticholinergic effects are generally mild and manageable. Nausea and gastrointestinal discomfort can occur, particularly if the medication is taken on an empty stomach. Taking TORRANE 50 with food can help minimize these digestive concerns.\nMore serious but less common side effects include orthostatic hypotension, which is a sudden drop in blood pressure upon standing that can lead to dizziness or fainting. Patients, especially older adults, should be cautioned to rise slowly from sitting or lying positions. In rare cases, TORRANE 50 may cause priapism, a prolonged and painful erection requiring immediate medical attention.\nCardiac considerations include potential changes in heart rhythm, and patients with pre-existing heart conditions should be monitored carefully. Some individuals may experience changes in alertness or cognitive function, which can affect the ability to drive or operate machinery safely, particularly when first starting treatment.\nAs with many antidepressants, there is a theoretical risk of increased suicidal thoughts, particularly in young adults and adolescents during the initial weeks of treatment. Close monitoring during this period is essential, and patients should immediately report any worsening of depression or emergence of suicidal thoughts.\nImportant Safety Information\nPatients should inform their healthcare provider about all medications, supplements, and herbal products they are taking, as TORRANE 50 can interact with numerous substances. Particularly significant interactions occur with monoamine oxidase inhibitors (MAOIs), other antidepressants, blood thinners, and medications affecting the central nervous system. Alcohol should be avoided during treatment as it can intensify sedation and increase the risk of adverse effects.\nTORRANE 50 should not be stopped abruptly without medical supervision, as discontinuation syndrome can occur, causing symptoms such as anxiety, agitation, and sleep disturbances. Healthcare providers will typically recommend gradual dose reduction when discontinuing the medication.\nConclusion\nTORRANE 50 (Trazodone Hydrochloride 50 mg) represents a valuable therapeutic option for individuals struggling with depression and sleep disturbances. Its unique dual-action mechanism, addressing both mood regulation and sleep quality, sets it apart in the landscape of psychiatric medications. The favorable side effect profile, particularly regarding sexual function and weight concerns, combined with its low abuse potential, makes TORRANE 50 an attractive choice for both patients and healthcare providers.",
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"description": "ESMOSTRUM IT: Comprehensive Product Guide\nProduct Overview\nESMOSTRUM IT is an advanced pharmaceutical formulation that combines two potent active ingredients—Esomeprazole and Itopride—to provide comprehensive relief from gastrointestinal disorders. This dual-action medication represents a significant advancement in the management of acid-related digestive conditions and motility disorders. By combining a proton pump inhibitor with a prokinetic agent, ESMOSTRUM IT addresses both the underlying causes and symptomatic manifestations of various digestive ailments, offering patients a complete therapeutic solution in a single, convenient dosage form.\nThe synergistic combination of Esomeprazole and Itopride makes ESMOSTRUM IT particularly effective for individuals suffering from gastroesophageal reflux disease (GERD), functional dyspepsia, and other conditions where both excessive acid production and impaired gastric motility contribute to discomfort and disease progression.\nActive Pharmaceutical Ingredients\nEsomeprazole\nEsomeprazole is the S-isomer of omeprazole and belongs to the class of medications known as proton pump inhibitors (PPIs). It works by specifically and irreversibly blocking the hydrogen-potassium adenosine triphosphatase enzyme system (the proton pump) located in the gastric parietal cells. This mechanism effectively reduces gastric acid secretion, providing sustained relief from acid-related symptoms and allowing damaged esophageal and gastric tissue to heal.\nItopride\nItopride is a prokinetic agent that enhances gastrointestinal motility through a dual mechanism of action. It acts as both a dopamine D2 receptor antagonist and an acetylcholinesterase inhibitor. By blocking dopamine receptors, it removes the inhibitory effect of dopamine on gastrointestinal motility, while its acetylcholinesterase inhibition increases acetylcholine levels, further promoting coordinated gastric contractions and improved gastric emptying.\nTherapeutic Uses and Indications\nESMOSTRUM IT is prescribed for a wide range of gastrointestinal conditions where both acid suppression and enhanced motility are therapeutically beneficial:\nGastroesophageal Reflux Disease (GERD)\nESMOSTRUM IT provides exceptional relief for patients suffering from GERD, a chronic condition where stomach acid frequently flows back into the esophagus. The esomeprazole component reduces acid production, while itopride improves the tone of the lower esophageal sphincter and accelerates gastric emptying, thereby reducing the frequency and severity of reflux episodes.\nFunctional Dyspepsia\nFor patients experiencing persistent or recurrent upper abdominal discomfort without an identifiable organic cause, ESMOSTRUM IT addresses multiple pathophysiological mechanisms. It relieves symptoms such as early satiety, postprandial fullness, epigastric pain, and bloating by normalizing gastric acid levels and improving gastric accommodation and emptying.\nPeptic Ulcer Disease\nESMOSTRUM IT aids in the healing of gastric and duodenal ulcers by creating an optimal healing environment through sustained acid suppression. The prokinetic action of itopride helps prevent stasis of gastric contents, which can exacerbate ulcer symptoms.\nNon-Ulcer Dyspepsia\nMany patients experience dyspeptic symptoms without evidence of ulceration. ESMOSTRUM IT effectively manages these symptoms by addressing both acid hypersecretion and delayed gastric emptying, two key factors in non-ulcer dyspepsia.\nGastroparesis-Related Symptoms\nIn conditions where gastric emptying is significantly delayed, the itopride component of ESMOSTRUM IT helps restore more normal gastric motility patterns, reducing associated symptoms like nausea, vomiting, and abdominal distension.\nKey Benefits and Advantages\nDual Mechanism of Action\nThe primary advantage of ESMOSTRUM IT lies in its comprehensive approach to gastrointestinal health. Rather than addressing only acid production or motility in isolation, this combination therapy tackles both aspects simultaneously, providing more complete symptom relief and better therapeutic outcomes.\nSuperior Acid Suppression\nEsomeprazole offers more consistent and prolonged acid suppression compared to many other acid-reducing medications. It provides sustained relief throughout the day and night, allowing patients to experience fewer breakthrough symptoms and better quality of life.\nEnhanced Gastric Motility\nThe itopride component specifically targets motility issues without crossing the blood-brain barrier significantly, meaning it provides prokinetic benefits with minimal central nervous system side effects. This results in improved gastric emptying, reduced bloating, and decreased feelings of fullness after meals.\nRapid Symptom Relief\nMany patients experience noticeable improvement in their symptoms within the first few days of treatment with ESMOSTRUM IT. The combination therapy addresses multiple symptom pathways simultaneously, leading to faster and more comprehensive relief.\nImproved Quality of Life\nBy effectively managing symptoms such as heartburn, regurgitation, nausea, bloating, and early satiety, ESMOSTRUM IT significantly enhances patients' daily functioning and overall well-being. Patients report better sleep quality, improved dietary tolerance, and reduced anxiety related to their digestive symptoms.\nConvenient Dosing\nThe combination of two active ingredients in a single formulation improves medication adherence by reducing pill burden. Patients appreciate the simplicity of taking one medication instead of multiple separate preparations.\nMucosal Healing Properties\nBeyond symptom relief, ESMOSTRUM IT promotes actual healing of damaged esophageal and gastric mucosa. The reduced acid environment created by esomeprazole allows inflamed and eroded tissue to regenerate properly.\nReduced Risk of Complications\nBy effectively controlling acid reflux and improving gastric emptying, ESMOSTRUM IT helps prevent potential complications of chronic GERD, such as esophageal strictures, Barrett's esophagus, and respiratory complications from aspiration.\nDosage and Administration\nESMOSTRUM IT should be taken exactly as prescribed by a healthcare professional. Typically, the medication is administered orally, preferably before meals to optimize its therapeutic effects. The standard dosing regimen usually involves once or twice daily administration, though individual requirements may vary based on the severity of the condition and patient response.\nThe medication should be swallowed whole with water and should not be crushed, chewed, or split, as this may affect the drug's release mechanism and therapeutic efficacy. Patients should maintain regular dosing schedules to ensure optimal acid suppression and motility enhancement throughout the day.\nSide Effects and Safety Considerations\nLike all medications, ESMOSTRUM IT may cause side effects in some individuals, though not everyone experiences them. Understanding potential adverse effects helps patients identify and report concerning symptoms promptly.\nCommon Side Effects\nGastrointestinal Effects: Some patients may experience diarrhea, constipation, abdominal pain, nausea, or flatulence, particularly during initial treatment. These effects are usually mild and often resolve as the body adjusts to the medication.\nHeadache: Mild to moderate headaches occur in a small percentage of patients and typically diminish with continued use.\nDizziness: Some individuals may experience lightheadedness or dizziness, particularly when standing up quickly.\nDry Mouth: Reduced saliva production may occur, leading to oral dryness and discomfort.\nLess Common Side Effects\nSkin Reactions: Rash, itching, or other dermatological manifestations may develop in sensitive individuals.\nSleep Disturbances: Some patients report insomnia or unusual dreams while taking the medication.\nIncreased Prolactin Levels: Itopride may cause mild elevation in prolactin levels, though clinical manifestations are rare.\nTaste Alterations: Changes in taste perception or metallic taste may occur temporarily.\nSerious Side Effects (Rare)\nWhile uncommon, certain serious adverse effects require immediate medical attention:\n\nSevere allergic reactions including difficulty breathing, facial swelling, or severe skin reactions\nSevere diarrhea that persists or contains blood\nIrregular heartbeat or palpitations\nMuscle weakness or pain\nSeizures or tremors\nSigns of liver problems including jaundice, dark urine, or persistent nausea\n\nLong-Term Considerations\nExtended use of proton pump inhibitors like esomeprazole has been associated with certain risks that patients should discuss with their healthcare providers:\n\nPotential reduction in calcium, magnesium, and vitamin B12 absorption\nSlightly increased risk of bone fractures with prolonged use\nPossible increased susceptibility to certain gastrointestinal infections\nRare cases of kidney problems\n\nRegular monitoring and periodic assessment by healthcare professionals help minimize these risks while maintaining therapeutic benefits.\nPrecautions and Contraindications\nPatients should inform their healthcare provider about all existing medical conditions, particularly liver disease, kidney problems, osteoporosis, low magnesium levels, or any gastrointestinal bleeding. ESMOSTRUM IT may interact with certain medications, including blood thinners, antifungals, HIV medications, and certain antibiotics. A complete medication review ensures safe and effective therapy.\nPregnant or breastfeeding women should only use ESMOSTRUM IT under strict medical supervision, as the safety profile in these populations requires careful consideration of potential risks and benefits.\nLifestyle Recommendations\nFor optimal therapeutic outcomes, patients taking ESMOSTRUM IT should complement their medication regimen with appropriate lifestyle modifications:\n\nAvoid trigger foods that exacerbate acid reflux, such as spicy foods, citrus, chocolate, caffeine, and alcohol\nMaintain a healthy body weight to reduce abdominal pressure\nEat smaller, more frequent meals rather than large portions\nAvoid lying down immediately after eating; wait at least two to three hours\nElevate the head of the bed if nighttime symptoms occur\nQuit smoking, as tobacco use significantly worsens reflux symptoms\nManage stress through relaxation techniques, as stress can exacerbate digestive symptoms\n\nConclusion\nESMOSTRUM IT represents a sophisticated and effective pharmaceutical solution for individuals struggling with complex gastrointestinal disorders involving both acid hypersecretion and impaired motility. By combining the powerful acid-suppressing capabilities of esomeprazole with the prokinetic benefits of itopride, this medication offers comprehensive symptom management that addresses the multifaceted nature of digestive disorders.",
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"description": "MIRTAZPRIME 30 is a pharmaceutical formulation containing Mirtazapine 30mg as per Indian Pharmacopoeia (IP) standards. This prescription medication belongs to a class of drugs known as tetracyclic antidepressants and represents an advanced therapeutic option for individuals struggling with major depressive disorder and related mental health conditions. Manufactured under stringent quality control measures, MIRTAZPRIME 30 offers patients a reliable and effective solution for managing depression while also addressing associated symptoms such as insomnia and anxiety.\nMirtazapine, the active pharmaceutical ingredient in MIRTAZPRIME 30, works through a unique dual mechanism that distinguishes it from other antidepressants. Unlike selective serotonin reuptake inhibitors (SSRIs), mirtazapine enhances the release of both norepinephrine and serotonin in the brain by blocking specific receptors. This innovative approach not only helps alleviate depressive symptoms but also provides sedative effects that can be particularly beneficial for patients experiencing sleep disturbances alongside depression.\nTherapeutic Uses and Applications\nMIRTAZPRIME 30 is primarily indicated for the treatment of major depressive disorder (MDD), a serious mental health condition characterized by persistent feelings of sadness, hopelessness, and loss of interest in daily activities. The medication has demonstrated significant efficacy in clinical trials, showing improvement in mood, energy levels, and overall quality of life for patients suffering from depression.\nBeyond its primary indication, healthcare providers may prescribe MIRTAZPRIME 30 for various off-label uses based on clinical judgment and patient needs. The medication has shown promise in managing generalized anxiety disorder, where excessive worry and tension interfere with daily functioning. Its sedative properties make it particularly valuable for patients experiencing insomnia related to depression or anxiety, as it can help restore healthy sleep patterns without the need for additional sleep medications.\nThe 30mg dosage strength represents a therapeutic level commonly prescribed for maintenance treatment after initial dose titration. Patients typically begin with lower doses and gradually increase to 30mg as their body adjusts to the medication and their symptoms require more robust management. This dosage provides an optimal balance between therapeutic efficacy and side effect management for many individuals.\nMIRTAZPRIME 30 may also be considered for patients who have not responded adequately to other antidepressant therapies, offering an alternative mechanism of action that can break through treatment-resistant depression. Additionally, its appetite-stimulating effects can be beneficial for patients experiencing significant weight loss due to depression or other medical conditions.\nKey Benefits and Therapeutic Advantages\nThe benefits of MIRTAZPRIME 30 extend beyond simple symptom relief, offering patients a multifaceted approach to mental health recovery. One of the most significant advantages is its relatively rapid onset of action compared to many other antidepressants. While most SSRIs require several weeks to demonstrate meaningful clinical improvement, patients taking mirtazapine often experience some relief from symptoms within one to two weeks, with continued improvement over subsequent weeks.\nThe dual neurotransmitter action of MIRTAZPRIME 30 provides comprehensive coverage of depressive symptoms. By enhancing both serotonergic and noradrenergic neurotransmission, the medication addresses the complex neurochemical imbalances underlying depression more thoroughly than single-mechanism antidepressants. This broader action can result in more complete symptom resolution and better overall outcomes.\nSleep improvement represents another crucial benefit of MIRTAZPRIME 30. The medication's sedative properties, particularly pronounced at lower doses, help patients fall asleep faster and enjoy more restorative sleep throughout the night. This is especially valuable since sleep disturbances are both a symptom and an exacerbating factor in depression. Better sleep quality contributes to improved daytime functioning, energy levels, and emotional regulation.\nUnlike many antidepressants that commonly cause sexual dysfunction, MIRTAZPRIME 30 has a relatively favorable profile in this regard. The medication is less likely to interfere with sexual function, making it an attractive option for patients who have experienced these troublesome side effects with other antidepressants. This characteristic can significantly improve treatment adherence and quality of life.\nThe appetite-stimulating effect, while considered a side effect by some, can be therapeutically beneficial for patients experiencing significant weight loss or poor appetite due to depression. MIRTAZPRIME 30 can help restore healthy eating patterns and reverse the physical decline that often accompanies severe depressive episodes.\nFurthermore, MIRTAZPRIME 30 does not typically cause the gastrointestinal side effects commonly associated with SSRI antidepressants, such as nausea, diarrhea, or stomach upset. This improved gastrointestinal tolerability enhances patient comfort and compliance with treatment regimens.\nPotential Side Effects and Safety Considerations\nWhile MIRTAZPRIME 30 offers numerous therapeutic benefits, patients should be aware of potential side effects that may occur during treatment. Understanding these effects helps patients make informed decisions and enables early identification of any concerning symptoms requiring medical attention.\nThe most commonly reported side effect is drowsiness or sedation, particularly during the initial weeks of treatment. This effect is typically most pronounced during the first few hours after taking the medication, which is why it's generally recommended for evening administration. Patients should exercise caution when driving, operating machinery, or engaging in activities requiring alertness until they understand how the medication affects them personally.\nIncreased appetite and weight gain represent another frequent side effect of MIRTAZPRIME 30. While beneficial for some patients, others may find this effect undesirable. Weight gain typically ranges from moderate to significant and appears to be dose-related. Patients concerned about weight should discuss dietary strategies and exercise plans with their healthcare provider.\nDry mouth is a common anticholinergic side effect that can cause discomfort but is generally manageable through increased fluid intake, sugar-free gum or candy, and good oral hygiene practices. Some patients may also experience dizziness, particularly when standing up quickly, due to the medication's effects on blood pressure regulation.\nConstipation may occur in some patients and can usually be managed through dietary modifications, increased fiber intake, adequate hydration, and regular physical activity. Less commonly, patients might experience confusion, abnormal dreams, or changes in thinking, particularly in older adults who may be more sensitive to the medication's effects.\nSerious side effects, while rare, require immediate medical attention. These include signs of allergic reactions such as rash, itching, swelling, severe dizziness, or difficulty breathing. Agranulocytosis, a dangerous decrease in white blood cells, is an extremely rare but serious complication that manifests as fever, sore throat, or signs of infection. Any unexplained fever or signs of infection should prompt immediate contact with a healthcare provider.\nSerotonin syndrome is another rare but potentially life-threatening condition that can occur when mirtazapine is combined with other medications affecting serotonin levels. Symptoms include agitation, hallucinations, rapid heartbeat, fever, excessive sweating, muscle stiffness, or coordination problems. Patients should inform their healthcare provider about all medications and supplements they are taking to avoid dangerous interactions.\nAbrupt discontinuation of MIRTAZPRIME 30 can lead to withdrawal symptoms, including nausea, anxiety, irritability, and flu-like symptoms. Therefore, any decision to stop the medication should be made in consultation with a healthcare provider who can develop an appropriate tapering schedule.\nImportant Usage Guidelines\nMIRTAZPRIME 30 should always be taken exactly as prescribed by a qualified healthcare professional. The medication is typically administered once daily, preferably in the evening before bedtime due to its sedative effects. Tablets should be swallowed whole with water and can be taken with or without food, though taking them with food may help reduce any stomach upset.\nConsistency in timing is important for maintaining stable blood levels of the medication and optimizing therapeutic effects. Patients should try to take their dose at approximately the same time each evening. If a dose is missed, it should be taken as soon as remembered unless it's close to the time for the next scheduled dose, in which case the missed dose should be skipped rather than doubling up.\nThe full therapeutic benefits of MIRTAZPRIME 30 may take several weeks to manifest. Patients should continue taking the medication as prescribed even if they don't feel immediate improvement. Premature discontinuation is a common reason for treatment failure in depression management.\nRegular follow-up appointments with the prescribing physician are essential for monitoring treatment response, adjusting dosages if necessary, and screening for potential side effects. Patients should maintain open communication with their healthcare team about their symptoms, concerns, and any changes in their condition.\nConclusion\nMIRTAZPRIME 30 represents a valuable therapeutic option in the comprehensive management of major depressive disorder and related conditions. Its unique mechanism of action, combining enhanced noradrenergic and serotonergic neurotransmission with sedative and appetite-stimulating properties, offers distinct advantages for carefully selected patients. The medication's ability to improve both mood symptoms and sleep disturbances makes it particularly useful for patients experiencing depression accompanied by insomnia.\nThe relatively favorable side effect profile, particularly regarding sexual function and gastrointestinal tolerability, enhances patient acceptance and adherence to treatment. While potential side effects such as sedation, increased appetite, and weight gain require monitoring and management, many patients find these effects tolerable compared to the debilitating symptoms of untreated depression.\nSuccess with MIRTAZPRIME 30, as with any antidepressant therapy, depends on proper patient selection, appropriate dosing, regular monitoring, and a comprehensive treatment approach that may include psychotherapy, lifestyle modifications, and social support alongside pharmacological intervention. Patients should work closely with their healthcare providers to optimize treatment outcomes and maintain long-term mental health wellness.\nThe decision to use MIRTAZPRIME 30 should always be made collaboratively between patient and physician, considering individual symptoms, treatment history, coexisting medical conditions, and personal preferences. With proper use under medical supervision, MIRTAZPRIME 30 can be an effective tool in helping patients reclaim their lives from the devastating effects of depression and move toward recovery and renewed well-being.",
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