Home> Products> improves neurotransmitter activity

{ "products": [ { "_id": "691437f0df62fb2c61ddbc40", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Ginkgo Biloba Extract and Piracetam Tablets ", "description": "Ginkgo Biloba Extract & Piracetam Tablets is a scientifically formulated neuroprotective and cognitive-enhancing combination designed to support memory, concentration, and brain function. It combines two powerful agents — Ginkgo Biloba, a time-tested herbal extract known for its circulation-enhancing and antioxidant properties, and Piracetam, a well-researched nootropic compound that enhances neuronal communication and cognitive performance.\n\nTogether, these two active ingredients work synergistically to improve cerebral blood flow, increase oxygen and nutrient delivery to the brain, and enhance mental clarity and alertness. The formulation is widely prescribed as a neurotonic and cognitive enhancer for individuals experiencing memory decline, age-related cognitive impairment, or neurological disorders such as dementia, Alzheimer’s disease, and cerebrovascular insufficiency.\n\nComposition\n\nEach film-coated tablet typically contains:\n\nGinkgo Biloba Extract (Standardized to contain 24% Flavone Glycosides & 6% Terpene Lactones) – 40 mg or 60 mg\n\nPiracetam – 800 mg\n\nExcipients – q.s.\n\nThe tablets are designed for oral administration, offering convenient dosage and high bioavailability.\n\nMechanism of Action\n1. Ginkgo Biloba Extract\n\nGinkgo Biloba, derived from the leaves of the ancient Ginkgo tree, is rich in flavonoids and terpenoids, which possess antioxidant, vasodilatory, and neuroprotective properties. It acts through several mechanisms:\n\nImproves microcirculation: Enhances blood flow to brain tissues by reducing blood viscosity and promoting vasodilation.\n\nAntioxidant action: Neutralizes free radicals that cause oxidative stress, protecting neurons from damage.\n\nIncreases neurotransmitter activity: Supports the release and uptake of acetylcholine and serotonin, improving mood and memory.\n\nReduces platelet aggregation: Improves oxygen supply to the brain and minimizes risk of ischemic injury.\n\n2. Piracetam\n\nPiracetam is a nootropic (cognitive enhancer) that improves neuronal efficiency and communication between brain cells.\nIts mechanism includes:\n\nEnhancing neuronal plasticity: Facilitates the transmission of impulses across synapses, improving learning and memory.\n\nImproving cerebral blood flow and metabolism: Enhances glucose utilization and oxygen consumption in the brain.\n\nProtecting neurons: Increases membrane fluidity and stabilizes nerve cells against hypoxic or oxidative damage.\n\nTogether, Ginkgo Biloba and Piracetam complement each other to enhance mental performance, protect neural structures, and improve cerebral function.\n\nUses and Indications\n\nGinkgo Biloba Extract & Piracetam Tablets are indicated for the following conditions:\n\nCognitive Decline and Memory Disorders:\n\nImproves memory, focus, and concentration in elderly individuals or those with mild cognitive impairment.\n\nDementia and Alzheimer’s Disease:\n\nUsed as supportive therapy to slow progression of degenerative brain disorders and enhance daily functioning.\n\nCerebrovascular Insufficiency:\n\nBeneficial in cases of reduced blood flow to the brain, helping alleviate symptoms like dizziness, headache, and mental fatigue.\n\nPost-Stroke Rehabilitation:\n\nEnhances neurological recovery and helps restore cognitive function after ischemic brain injury.\n\nVertigo and Tinnitus (Ringing in the Ears):\n\nImproves inner ear circulation, reducing dizziness and balance-related issues.\n\nLearning Disorders and Attention Deficits:\n\nImproves attention span and memory recall in both adults and children.\n\nNeuroprotective Supplement for Elderly:\n\nMaintains brain vitality and helps prevent age-related cognitive decline.\n\nKey Benefits\n\nEnhances Memory and Concentration:\nThe synergistic effect of Ginkgo Biloba and Piracetam improves synaptic transmission and neuroplasticity, enhancing learning, focus, and recall.\n\nBoosts Cerebral Circulation:\nGinkgo Biloba improves microcirculation within brain tissues, ensuring efficient delivery of oxygen and glucose to neurons.\n\nProtects Against Neurodegeneration:\nThe powerful antioxidant activity of flavonoids and terpenes from Ginkgo Biloba helps neutralize harmful free radicals, delaying age-related brain cell damage.\n\nImproves Cognitive Function in Dementia:\nClinical studies have shown improved cognition, mood, and behavior in patients with Alzheimer’s and vascular dementia with this combination.\n\nRestores Energy and Mental Clarity:\nPiracetam enhances brain metabolism and ATP synthesis, combating mental fatigue and promoting alertness.\n\nAids Recovery After Stroke or Brain Injury:\nEnhances neural regeneration, oxygen utilization, and cerebral function in post-stroke rehabilitation.\n\nReduces Dizziness, Vertigo, and Tinnitus:\nGinkgo’s vasodilatory and anti-platelet properties improve blood flow to the inner ear and brain, alleviating these symptoms.\n\nSafe and Well-Tolerated:\nNon-sedating, non-addictive, and suitable for long-term use under medical supervision.\n\nDosage and Administration\n\nAdults: One tablet two or three times daily, or as directed by a physician.\n\nElderly Patients: Dosage may be adjusted according to tolerance and medical condition.\n\nChildren: Use only if prescribed by a doctor.\n\nTablets should be swallowed whole with water, preferably after meals to avoid gastrointestinal discomfort.\n\nPrecautions and Warnings\n\nMedical Supervision Required: Should only be used under the guidance of a healthcare professional, especially for elderly patients or those on multiple medications.\n\nBleeding Disorders: Ginkgo Biloba may increase bleeding risk; avoid in patients with clotting disorders or those taking anticoagulants.\n\nSurgery: Discontinue use at least two weeks before scheduled surgery to minimize bleeding risk.\n\nEpilepsy: Piracetam may lower the seizure threshold; caution advised in epileptic patients.\n\nPregnancy and Lactation: Safety not well established; use only if prescribed by a doctor.\n\nDriving or Operating Machinery: Some individuals may experience dizziness or drowsiness; caution advised.\n\nPossible Side Effects\n\nWhile generally safe, Ginkgo Biloba Extract & Piracetam Tablets may cause mild, transient side effects in some users. These typically resolve upon dosage adjustment or discontinuation.\n\nCommon Side Effects:\n\nHeadache or mild dizziness\n\nNausea or stomach discomfort\n\nNervousness or restlessness\n\nInsomnia (if taken late in the day)\n\nLess Common Side Effects:\n\nAllergic skin rash or itching\n\nGastrointestinal upset\n\nPalpitations or rapid heartbeat\n\nMild bleeding (nosebleed, bruising) in sensitive individuals\n\nTremors (rare, usually at higher doses)\n\nSeek medical help immediately if severe allergic reactions, confusion, or unusual bleeding occur.\n\nDrug Interactions\n\nAnticoagulants and Antiplatelet Agents (e.g., Warfarin, Aspirin): May increase bleeding risk.\n\nNSAIDs (e.g., Ibuprofen): Combined use may enhance bleeding tendency.\n\nAntiepileptic Medications: Use with caution as Piracetam may affect seizure control.\n\nHerbal Supplements (e.g., Garlic, Ginseng): May potentiate anticoagulant effects.\n\nStorage and Handling\n\nStore below 30°C, protected from moisture and direct sunlight.\n\nKeep out of reach of children.\n\nDo not use tablets past the expiry date or if the blister pack is damaged.\n\nConclusion\n\nGinkgo Biloba Extract & Piracetam Tablets represent a powerful blend of herbal wisdom and modern neuroscience, formulated to promote optimal brain function and long-term cognitive health. By enhancing blood circulation to the brain, protecting neurons from oxidative damage, and improving neurotransmitter activity, this combination supports memory, focus, and mental agility across all age groups.\n\nIdeal for individuals suffering from age-related memory loss, stress-induced mental fatigue, or neurological disorders, this formulation provides comprehensive neuroprotection and cognitive enhancement in a safe, well-tolerated form.", "price": 250.0, "discountamount": 75.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2203, "imageuri": "https://productimages.withfloats.com/actual/691437f3b2490379b1b47e37.png", "tileimageuri": "https://productimages.withfloats.com/tile/691437f3b2490379b1b47e37.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-12T07:32:00.682Z", "updatedon": "2025-11-12T07:32:00.682Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/ginkgo-biloba-extract-and-piracetam-tablets-/2203", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Steris Healthcare Pvt Ltd", "category": "NEUROLOGY RANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6912f583bd635de199b5deaf", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Gabapentin Tablets 400 mg", "description": "Gabapentin Tablets 400 mg is a widely prescribed medication belonging to the class of anticonvulsants or antiepileptic drugs. It is primarily used to treat neuropathic pain (nerve pain) and epileptic seizures. Gabapentin works by affecting chemicals and nerve signals in the brain that cause seizures or pain.\n\nEach tablet contains 400 mg of Gabapentin as the active ingredient, formulated to deliver reliable absorption and consistent therapeutic results. It helps manage chronic nerve pain resulting from conditions such as diabetic neuropathy, postherpetic neuralgia (pain following shingles), and sciatica. In addition, Gabapentin is also used as adjunctive therapy in the management of partial seizures (with or without secondary generalization) in adults and children.\n\nWith its dual role in pain control and seizure prevention, Gabapentin 400 mg offers comprehensive neurological support and enhances the quality of life for individuals suffering from long-term nerve-related conditions.\n\nUses and Therapeutic Indications\n\nGabapentin 400 mg Tablets are used to treat the following conditions:\n\nNeuropathic Pain:\nHelps relieve nerve pain caused by diabetes (diabetic neuropathy), shingles (postherpetic neuralgia), spinal cord injury, or other nerve damage.\n\nEpilepsy (Partial Seizures):\nUsed as adjunct therapy to control partial seizures with or without secondary generalization in adults and children over 12 years.\n\nFibromyalgia:\nProvides symptomatic relief from chronic musculoskeletal pain and nerve hypersensitivity.\n\nRestless Legs Syndrome (RLS):\nMay be used to reduce discomfort and restlessness in the legs, improving sleep quality.\n\nPost-Surgical Nerve Pain or Neuralgia:\nHelps reduce persistent nerve pain following surgeries or trauma.\n\nBy modulating neurotransmitter activity, Gabapentin helps restore normal nerve function and decreases abnormal excitability in the nervous system.\n\nKey Benefits\n\nEffective Relief from Nerve Pain:\nGabapentin 400 mg provides targeted relief from chronic nerve-related pain, often resistant to standard painkillers.\n\nPrevents and Controls Seizures:\nWorks as an antiepileptic drug to reduce abnormal electrical activity in the brain, preventing seizure episodes.\n\nImproves Sleep and Quality of Life:\nBy relieving persistent nerve pain, Gabapentin helps improve sleep patterns and enhances overall well-being.\n\nSuitable for Long-Term Use:\nWell-tolerated for chronic conditions requiring prolonged therapy, such as diabetic neuropathy or postherpetic neuralgia.\n\nAdjunctive Flexibility:\nCan be safely combined with other antiepileptic or pain management medications under medical supervision.\n\nReduces Dependence on Opioids:\nAn excellent non-opioid alternative for managing chronic neuropathic pain, helping reduce the risks associated with opioid use.\n\nWell-Studied and Trusted:\nBacked by extensive clinical research and years of use, Gabapentin remains one of the most prescribed and reliable treatments for neuropathic conditions.\n\nPossible Side Effects\n\nAlthough Gabapentin Tablets 400 mg are generally well tolerated, some patients may experience mild to moderate side effects, particularly at the beginning of treatment or during dose adjustments. These may include:\n\nDrowsiness or Fatigue: A common effect, especially when starting the medication.\n\nDizziness or Unsteadiness: May occur temporarily as the body adjusts.\n\nSwelling of Hands or Feet (Peripheral Edema): Usually mild and reversible.\n\nTremors or Coordination Issues: Infrequent but possible in sensitive patients.\n\nBlurred Vision or Double Vision: May occur due to its neurological effects.\n\nWeight Gain or Increased Appetite: Observed in some long-term users.\n\nMood Changes or Irritability: Rarely, Gabapentin may affect mood or concentration.\n\nPrecautions:\n\nAvoid driving or operating heavy machinery until you know how Gabapentin affects you.\n\nInform your doctor if you have kidney problems, as dosage adjustments may be needed.\n\nAbrupt discontinuation should be avoided; the dose should be gradually reduced under medical supervision.\n\nAlcohol and certain medications (like opioids or sedatives) can increase drowsiness when taken with Gabapentin.\n\nConclusion\n\nGabapentin Tablets 400 mg are a trusted and effective solution for managing neuropathic pain and epileptic seizures. By regulating abnormal nerve signals in the brain and spinal cord, Gabapentin offers significant relief from chronic nerve-related pain, improves sleep, and enhances daily functionality.\n\nIts proven safety profile, versatility in multiple conditions, and long-term tolerability make it one of the most commonly prescribed medications for nerve pain and seizure control worldwide.\n\nWhen used as directed by a healthcare professional, Gabapentin 400 mg not only alleviates pain and discomfort but also helps patients regain comfort, confidence, and control over their lives.", "price": 290.0, "discountamount": 87.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2198, "imageuri": "https://productimages.withfloats.com/actual/69141e09fb4d3eac164c0add.png", "tileimageuri": "https://productimages.withfloats.com/tile/69141e09fb4d3eac164c0add.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-11T08:36:19.985Z", "updatedon": "2025-11-12T05:41:29.084Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/gabapentin-tablets-400-mg/2198", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Steris Healthcare Pvt. Ltd.", "category": "NEUROLOGY RANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "683d8fd4990bc014137527ef", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "STERIMMUNE HEPA PROTEIN POWDER", "description": "STERIMMUNE HEPA PROTEIN POWDER is a scientifically formulated nutritional supplement designed to support overall wellness, energy, and liver function. Enriched with essential multivitamins, vital minerals, high-quality protein, and choline, this powder provides a balanced solution to meet daily nutritional needs. Ideal for individuals recovering from illness, with weakened immunity, or seeking a daily health boost, it contributes to enhanced vitality and supports organ health—particularly liver health.\n\nKey Ingredients\nMultivitamins: Includes a broad spectrum of vitamins such as A, B-complex, C, D, and E that support immune health, metabolism, vision, and energy production.\n\nMulti Minerals: Essential minerals like calcium, magnesium, zinc, selenium, and iron help in strengthening bones, oxygen transport, antioxidant defense, and enzymatic functions.\n\nProtein: High-quality protein helps in muscle repair, tissue regeneration, and maintaining lean body mass.\n\nCholine: An essential nutrient that plays a critical role in liver function, brain development, nerve function, and fat metabolism.\n\nKey Benefits\nProvides complete nutritional support for the body’s daily needs\n\nPromotes healthy immune system function\n\nSupports liver health and helps improve fat metabolism\n\nEnhances muscle recovery and energy production\n\nImproves cognitive function and memory through the action of choline\n\nSupports antioxidant activity to combat oxidative stress\n\nIdeal for recovery from chronic illness or surgery\n\nSuitable for all age groups including growing children, adults, and the elderly\n\nHow Does It Work?\nSTERIMMUNE HEPA PROTEIN POWDER works by replenishing essential nutrients that may be deficient due to poor diet, illness, or increased physiological demand.\n\nThe multivitamins and minerals help activate numerous biological processes including enzyme function, energy release, and immune defense.\n\nProtein aids in muscle growth, cellular repair, and maintaining body structure.\n\nCholine supports liver detoxification, helps prevent fat accumulation in the liver, and improves neurotransmitter activity.\n\nThe synergistic effect of these ingredients ensures optimal absorption and utilization, keeping the body nourished and resilient.\n\nDirections for Use\nMix one or two tablespoons (approx. 15–30g) of the powder with 200 ml of lukewarm milk or water.\n\nStir well until completely dissolved and consume immediately.\n\nTake once or twice daily, or as directed by a healthcare professional.\n\nCan be consumed with breakfast or between meals for best results.\n\nSide Effects\nSTERIMMUNE HEPA PROTEIN POWDER is generally well tolerated when taken as directed. However, mild side effects may occur in sensitive individuals such as:\n\nBloating or gas due to protein digestion\n\nMild nausea if taken on an empty stomach\n\nAllergic reaction in individuals sensitive to any ingredient (consult label)\n\nAlways consult your physician before starting any supplement, especially if you are pregnant, breastfeeding, or have a chronic medical condition.\n\n", "price": 427.0, "discountamount": 129.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": [ "200 ml", "pregnant breastfeeding", "individuals sensitive", "gas due", "sensitive individuals", "healthcare professional", "consume immediately", "completely dissolved", "water stir", "lukewarm milk", "resilient directions", "body nourished", "utilization keeping", "synergistic effect", "deficient due", "age groups", "surgery suitable", "critical role", "broad spectrum", "enhanced vitality", "weakened immunity", "individuals recovering", "balanced solution", "wellness energy", "bodys daily", "chronic illness", "essential nutrient", "ingredient consult label", "poor diet illness", "complete nutritional support", "liver function enriched", "daily health boost", "meet daily nutritional", "chronic medical condition", "replenishing essential nutrients", "mild side effects", "tablespoons approx 1530g", "improves neurotransmitter activity", "increased physiological demand", "growing children adults" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2129, "imageuri": "https://productimages.withfloats.com/actual/683d8fd9ff3655f5a866e74c.png", "tileimageuri": "https://productimages.withfloats.com/tile/683d8fd9ff3655f5a866e74c.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-06-02T11:49:40.984Z", "updatedon": "2025-06-02T11:52:09.316Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/sterimmune-hepa-protein-powder/2129", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MULTIVITAMIN, MULTI MINERAL PROTEIN POWDER WITH CHOLINE", "category": "GENERAL RANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "66698007162db023604894db", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "DONEPAZE M ", "description": "DONEPAZE M \nDonepazil 5mg + Mentatime 5mg\nIntroduction\nDONEPAZE M combines Donepezil (5 mg) and Memantine (5 mg) to offer a comprehensive treatment for Alzheimer's disease and cognitive enhancement. This combination medication works by targeting multiple pathways involved in the cognitive decline associated with Alzheimer's, providing a more robust solution for managing the symptoms of the disease and improving overall brain function.\n\nKey Ingredients and Their Benefits\nDonepezil (5 mg)\nCognitive Enhancement: Donepezil is a cholinesterase inhibitor that increases the levels of acetylcholine, a neurotransmitter essential for memory and learning, in the brain.\nMemory Improvement: By slowing the breakdown of acetylcholine, Donepezil helps enhance memory and learning capabilities in patients with Alzheimer's disease.\nSymptom Management: It effectively manages the symptoms of mild to moderate Alzheimer's disease, helping patients maintain their daily functions and quality of life.\nSlow Progression: Donepezil can slow the progression of Alzheimer's symptoms, providing significant benefits to patients and caregivers.\nMemantine (5 mg)\nNMDA Receptor Antagonist: Memantine works by blocking NMDA receptors, which are involved in the overactivation that can lead to neuronal damage in Alzheimer's disease.\nNeuroprotection: By regulating the activity of glutamate, Memantine helps protect neurons from excitotoxicity and supports brain health.\nCognitive Improvement: Memantine helps improve cognitive function, including memory, attention, and problem-solving skills in patients with moderate to severe Alzheimer's disease.\nBehavioral Symptom Management: It can also help manage behavioral symptoms associated with Alzheimer's, such as agitation and aggression.\nBenefits of DONEPAZE M\nDual Mechanism of Action: DONEPAZE M combines the benefits of Donepezil and Memantine, targeting multiple pathways involved in Alzheimer's disease for more comprehensive symptom management.\nEnhanced Cognitive Function: The combination improves cognitive abilities, including memory, attention, and problem-solving skills, in patients with Alzheimer's disease.\nSymptom Relief: It effectively manages both cognitive and behavioral symptoms of Alzheimer's, helping patients maintain their independence and perform daily activities.\nNeuroprotection: DONEPAZE M provides neuroprotective benefits by regulating neurotransmitter activity and protecting neurons from damage.\nOnce-Daily Dosing: The convenience of once-daily dosing improves patient compliance and ensures consistent therapeutic effects.\nDosage and Administration\nDosage\nAlzheimer’s Disease: The recommended starting dose is one tablet (Donepezil 5 mg + Memantine 5 mg) taken once daily. The dosage may be adjusted by the healthcare provider based on the patient's response and tolerance.\nAdministration\nOral Use: Swallow the tablet whole with a full glass of water. It can be taken with or without food.\nConsistency: For optimal results, take DONEPAZE M at the same time each day to maintain consistent medication levels in your bloodstream.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order NOW\nhttps://www.sterisonline.com/product/donepaze-m-133559", "price": 167.0, "discountamount": 50.1, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "mild", "life", "food", "EMAIL", "Order", "water", "Action", "Dosing", "quality", "disease", "neurons", "Oral Use", "response", "patients", "attention", "agitation", "same time", "tolerance", "glutamate", "Donepazil", "Mentatime", "Memantine", "breakdown", "aggression", "one tablet", "full glass", "caregivers", "DONEPAZE M", "bloodstream", "Consistency", "moderate to", "convenience", "information", "Introduction", "sterispharma", "sterisonline", "independence", "brain health", "acetylcholine", "starting dose", "CALL/WHATSAPP", "NMDA receptors", "excitotoxicity", "Dual Mechanism", "Symptom Relief", "Donepezil 5 mg", "overactivation", "Donepezil (5 mg", "Neuroprotection", "robust solution", "Key Ingredients", "daily functions", "optimal results", "neuronal damage", "severe Alzheimer", "Slow Progression", "daily activities", "cognitive decline", "multiple pathways", "moderate Alzheimer", "Memory Improvement", "patient compliance", "cognitive abilities", "behavioral symptoms", "healthcare provider", "significant benefits", "cognitive enhancement", "learning capabilities", "Administration Dosage", "Cognitive Improvement", "combination medication", "overall brain function", "problem-solving skills", "comprehensive treatment", "NMDA Receptor Antagonist", "neuroprotective benefits", "cholinesterase inhibitor", "neurotransmitter activity", "Enhanced Cognitive Function", "consistent medication levels", "Behavioral Symptom Management", "consistent therapeutic effects", "comprehensive symptom management" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1823, "imageuri": "https://productimages.withfloats.com/actual/666980260b4fc76a99a080d2.jpg", "tileimageuri": "https://productimages.withfloats.com/tile/666980260b4fc76a99a080d2.jpg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-12T11:01:27.347Z", "updatedon": "2024-06-27T05:51:11.327Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/donepaze-m-/1823", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "DONEPAZE M ", "category": "NEUROLOGY RANGE", "tags": [ "Mentatime 5mg", "Donepazil 5mg", "donepaze m tablet uses in hindi", "donepaze m tablet uses in telugu", "DONEPAZE M tablets price" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "691b190c54131a1a1c761716", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Dothiepin 50mg and Methylcobalamin 1500mcg | DROTHEPINE M 50", "description": "DROTHEPINE M 50 is a specialized combination medicine that blends the antidepressant properties of Dothiepin 50mg with the nerve-repairing benefits of Methylcobalamin 1500mcg. This balanced formulation is designed to support individuals dealing with depression, anxiety, neuropathic pain, and vitamin B12 deficiency–related nerve issues. Dothiepin, a tricyclic antidepressant, helps restore neurotransmitter balance in the brain, promoting emotional stability and mental clarity. Methylcobalamin, an active form of vitamin B12, plays an essential role in nerve regeneration and optimal neurological functioning. Together, these two powerful ingredients make DROTHEPINE M 50 an effective choice for improving mood, reducing nerve discomfort, and enhancing overall quality of life.\n\nUses\n\nDROTHEPINE M 50 is commonly prescribed for a wide range of mental and neurological conditions. Its primary uses include:\n\nTreatment of Depression and Anxiety: Helps relieve persistent low mood, tension, nervousness, and emotional imbalance.\n\nManagement of Neuropathic Pain: Effective for nerve pain caused by diabetes, nerve injuries, and chronic nerve degeneration.\n\nCorrection of Vitamin B12 Deficiency: Supports nerve health and improves symptoms associated with B12 deficiency.\n\nRelief from Tingling, Burning, and Numbness: Suitable for individuals experiencing peripheral neuropathy symptoms.\n\nImproves Sleep Patterns: Beneficial for individuals suffering from insomnia or disturbed sleep linked to depression or mental stress.\n\nBenefits\n\nThe combination of Dothiepin 50mg and Methylcobalamin 1500mcg offers several key therapeutic benefits:\n\n1. Balanced Mood Enhancement\n\nDothiepin works by regulating serotonin and norepinephrine levels in the brain, helping alleviate depressive symptoms, anxiety, and emotional trauma.\n\n2. Supports Nerve Repair and Regeneration\n\nMethylcobalamin aids in repairing damaged nerve cells, enhancing nerve signal transmission, and reducing nerve-related discomfort.\n\n3. Comprehensive Relief for Mental and Nerve Conditions\n\nBy addressing both mental health concerns and nerve pain, DROTHEPINE M 50 offers a dual-action therapeutic approach.\n\n4. Enhances Cognitive Performance\n\nImproved neurotransmitter balance and nerve function contribute to better concentration, memory, and overall mental clarity.\n\n5. Helps Improve Daily Functionality\n\nWith reduced pain, improved mood, and better sleep quality, patients can experience enhanced productivity and a better quality of life.\n\nDosage\n\nThe typical recommended dosage for DROTHEPINE M 50 is one tablet per day, or as directed by a healthcare provider.\n\nTablets should be taken with water, preferably after a meal to support absorption and reduce stomach upset.\n\nDosage may vary depending on the individual’s medical history, condition severity, and treatment response.\n\nConsistent daily use is essential for achieving long-term benefits.\n\nDo not change the dosage or stop the medication abruptly without consulting a doctor.\n\nSide Effects\n\nLike all medications, DROTHEPINE M 50 may cause some side effects, although not everyone experiences them. Common side effects may include:\n\nDrowsiness or dizziness\n\nDry mouth\n\nConstipation\n\nBlurred vision\n\nIncreased appetite or slight weight gain\n\nMild nausea\n\nFatigue or weakness\n\nOccasional headaches\n\nSevere side effects are rare, but if you experience rapid heartbeat, severe dizziness, allergic reactions, or mood changes, seek medical attention immediately.\n\nPrecautions and Warning\n\nAvoid alcohol use during treatment, as it may increase drowsiness and impair judgment.\n\nNot advisable during pregnancy or breastfeeding unless recommended by a healthcare professional.\n\nIndividuals with heart disease, glaucoma, epilepsy, or liver problems should inform their doctor before starting this medication.\n\nThis medicine may cause drowsiness—avoid driving or operating machinery until its effects are known.\n\nDo not discontinue the medication suddenly; dosage adjustments must be done under medical supervision.\n\nStore the product in a cool, dry place and keep it out of reach of children.\n\nConclusion\n\nDROTHEPINE M 50, a powerful combination of Dothiepin 50mg and Methylcobalamin 1500mcg, provides an effective and balanced solution for managing depression, anxiety, neuropathic pain, and vitamin B12 deficiency. Its dual-action formula supports mental health while promoting nerve repair, improving cognitive performance, and offering long-lasting relief from discomfort. When taken under medical guidance, DROTHEPINE M 50 can help restore emotional stability, reduce nerve symptoms, and significantly enhance overall well-being.", "price": 270.0, "discountamount": 81.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2210, "imageuri": "https://productimages.withfloats.com/actual/691b190e7361b0a74ff6bb95.png", "tileimageuri": "https://productimages.withfloats.com/tile/691b190e7361b0a74ff6bb95.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-17T12:46:04.063Z", "updatedon": "2025-11-17T12:46:04.063Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/dothiepin-50mg-and-methylcobalamin-1500mcg-drothepine-m-50/2210", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Steris Healthcare Pvt Ltd", "category": "NEUROLOGY", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "691b17834c6b1fd261aeaae2", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Dothiepin 75mg and Methylcobalamin 1500mcg | DROTHEPINE M 75", "description": "DROTHEPINE M 75 is a clinically formulated combination that unites the therapeutic strength of Dothiepin 75mg, a tricyclic antidepressant, with Methylcobalamin 1500mcg, an essential neurovitamin known for its nerve-repairing properties. This high-strength formulation is designed to support individuals facing depression, anxiety, neuropathic pain, and nerve degeneration associated with vitamin B12 deficiency. Dothiepin works by restoring chemical balance in the brain to improve mood, sleep, and emotional well-being. Meanwhile, Methylcobalamin helps repair damaged nerves and enhances nerve conduction. Together, these components make DROTHEPINE M 75 a comprehensive solution for boosting both mental health and neurological function.\n\nUses\n\nDROTHEPINE M 75 is recommended for the treatment and management of several psychological and nerve-related conditions. Its primary uses include:\n\nTreatment of Major Depression and Anxiety Disorders: Helps reduce persistent sadness, irritability, and emotional instability.\n\nManagement of Neuropathic Pain: Effective for nerve pain caused by diabetes, injuries, and chronic nerve damage.\n\nCorrection of Vitamin B12 Deficiency: Supports proper nerve functioning in individuals with low B12 levels.\n\nRelief from Nerve Tingling, Burning, and Numbness: Ideal for managing peripheral neuropathy symptoms.\n\nSupport for Sleep Disturbances Linked to Stress or Depression: Promotes relaxation and improves sleep quality.\n\nThese multifaceted uses make DROTHEPINE M 75 a trusted choice for patients needing both emotional and neurological support.\n\nBenefits\n\nThe powerful combination of Dothiepin 75mg and Methylcobalamin 1500mcg delivers a wide range of therapeutic benefits:\n\n1. Enhanced Mood Regulation\n\nDothiepin helps restore the balance of neurotransmitters like serotonin and norepinephrine, providing relief from depression and anxiety while enhancing overall emotional stability.\n\n2. Supports Nerve Regeneration\n\nMethylcobalamin promotes nerve cell repair, improves nerve signaling, and helps reduce neuropathic pain more effectively than standard B12 forms.\n\n3. Dual Action for Mental and Nerve Health\n\nBy targeting both emotional and physical discomfort, DROTHEPINE M 75 offers holistic relief, making daily life more manageable.\n\n4. Improved Sleep and Cognitive Clarity\n\nThe antidepressant component reduces stress-related sleep disturbances and supports improved focus, concentration, and memory.\n\n5. Best-in-Class Strength for Long-Lasting Relief\n\nWith a higher 75mg dose of Dothiepin, this formulation provides sustained action throughout the day, delivering dependable symptom control.\n\nDosage\n\nThe typical recommended dosage of DROTHEPINE M 75 is one tablet once daily, or as directed by a healthcare professional.\n\nTake the tablet with water, preferably after meals to reduce gastrointestinal discomfort.\n\nDosage may differ based on individual needs, severity of symptoms, and medical history.\n\nConsistency is key—take the medication at the same time each day for optimal results.\n\nDo not increase, reduce, or stop the dosage abruptly without consulting a doctor.\n\nSide Effects\n\nAlthough DROTHEPINE M 75 is generally well-tolerated, some individuals may experience mild side effects, especially at the beginning of treatment. These may include:\n\nDrowsiness or dizziness\n\nDry mouth\n\nConstipation\n\nBlurred vision\n\nFatigue or tiredness\n\nIncreased appetite or weight changes\n\nMild nausea or headache\n\nSevere side effects are uncommon, but seek immediate medical attention if you experience irregular heartbeat, severe dizziness, allergic reactions, or sudden mood changes.\n\nPrecautions and Warning\n\nAvoid alcohol while taking this medication, as it may intensify drowsiness and impair alertness.\n\nNot recommended during pregnancy or breastfeeding unless prescribed by a healthcare provider.\n\nPeople with heart problems, glaucoma, epilepsy, liver disease, or urinary retention must inform their doctor before use.\n\nThis medicine may cause drowsiness—avoid driving or operating machinery until you know how it affects you.\n\nDo not discontinue the medicine abruptly; dosage reduction should be supervised by a doctor.\n\nKeep the medication stored in a cool, dry place away from children.\n\nConclusion\n\nDROTHEPINE M 75, formulated with Dothiepin 75mg and Methylcobalamin 1500mcg, is an advanced dual-action therapy designed to support emotional well-being and nerve health simultaneously. It effectively treats depression, anxiety, neuropathic pain, and vitamin B12 deficiency while promoting nerve repair and cognitive clarity. When taken under medical supervision, this powerful combination helps restore balance, reduce discomfort, and improve your overall quality of life.", "price": 360.0, "discountamount": 108.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2209, "imageuri": "https://productimages.withfloats.com/actual/691b1786743983a7e3b55dc4.png", "tileimageuri": "https://productimages.withfloats.com/tile/691b1786743983a7e3b55dc4.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-17T12:39:31.538Z", "updatedon": "2025-11-17T12:41:13.788Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/dothiepin-75mg-and-methylcobalamin-1500mcg-drothepine-m-75/2209", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Steris Healthcare Pvt. Ltd.", "category": "NEUROLOGY", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6916c002d152b8cabef859ea", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Miltefosine Capsules", "description": "Miltefosine Capsules are an important oral medication widely recognized for their effectiveness in treating Visceral Leishmaniasis (Kala-azar), Cutaneous Leishmaniasis, and certain protozoal infections. As the first and only oral drug approved for the treatment of Leishmaniasis, Miltefosine has significantly transformed patient care by offering a convenient and reliable alternative to painful injectable therapies. The medication belongs to the class of alkylphosphocholine drugs and is known for its potent antiparasitic and cytotoxic actions.\n\nMiltefosine Capsules are typically prescribed by healthcare professionals when a confirmed diagnosis of Leishmaniasis has been made, or when the patient is not responding adequately to other modes of therapy. Its high absorption rate, ease of administration, and consistent therapeutic activity make it a cornerstone in parasitic infection management across endemic regions.\n\nWhat Are Miltefosine Capsules?\n\nMiltefosine is an oral antiparasitic medication designed to eliminate Leishmania parasites by disrupting their cell membranes and metabolic functions. It was originally studied for anticancer activities but later found to be highly effective against various Leishmania species. Unlike conventional treatment options that require hospitalization and injections, Miltefosine offers a non-invasive, at-home oral therapy option, improving both patient comfort and compliance.\n\nMiltefosine Capsules are generally marketed in different strengths such as 50 mg. The duration of treatment usually ranges between 28–30 days depending on the medical condition and severity.\n\nUses of Miltefosine Capsules\n\nMiltefosine Capsules are primarily prescribed for:\n\n1. Visceral Leishmaniasis (Kala-azar)\n\nThis is a severe, life-threatening parasitic disease affecting internal organs such as the spleen, liver, and bone marrow. Miltefosine is considered one of the most effective oral treatment options for Kala-azar and is widely used in India and other tropical regions where the disease is endemic.\n\n2. Cutaneous Leishmaniasis\n\nIt causes skin lesions, ulcers, and disfiguring scars. Miltefosine works by targeting the parasite in skin tissues, promoting faster healing and reducing complications.\n\n3. Mucocutaneous Leishmaniasis\n\nThough less common, this form affects mucous membranes of the nose, mouth, and throat. Miltefosine plays a major role in preventing progressive tissue destruction.\n\n4. Off-Label Uses\n\nIn some cases, doctors may prescribe Miltefosine for:\n\nCertain protozoal infections\n\nAmoebic keratitis (rare condition affecting the eye)\n\nParasitic infections resistant to other treatments\n\nHowever, these uses should only be followed under strict medical supervision.\n\nHow Miltefosine Works\n\nMiltefosine acts directly on parasitic cells by:\n\nDisrupting cell membrane integrity\n\nInterfering with phospholipid metabolism\n\nTriggering apoptosis-like cell death in parasites\n\nWeakening parasite reproduction and survival\n\nThis multi-target mechanism makes Miltefosine one of the most powerful oral antiparasitic medications available today.\n\nKey Benefits of Miltefosine Capsules\n1. Highly Effective Oral Treatment\n\nUnlike older treatments requiring multiple injections, Miltefosine provides a simple oral dosage, eliminating the need for hospitalization or painful procedures.\n\n2. Excellent Patient Compliance\n\nThe convenience of taking capsules at home significantly improves adherence to treatment, especially in rural or resource-limited areas.\n\n3. Strong Activity Against Leishmania Species\n\nMiltefosine’s broad-spectrum antiparasitic properties make it effective against several strains of Leishmania responsible for different clinical presentations of the disease.\n\n4. Lower Risk of Severe Treatment Complications\n\nCompared to traditional injectable therapies like antimonials, Miltefosine has a better safety profile when used under medical supervision.\n\n5. Reduces Disease Transmission\n\nBy effectively eliminating parasites from the body, Miltefosine helps reduce the overall disease burden in endemic communities.\n\n6. Faster Healing of Skin Lesions\n\nPatients with Cutaneous Leishmaniasis experience faster recovery, reduced lesion size, and minimal scarring when treatment is taken on time.\n\n7. Well-Studied and Recommended\n\nMiltefosine is recommended by WHO and national health authorities in many countries as a frontline treatment for Kala-azar.\n\nPossible Side Effects of Miltefosine Capsules\n\nWhile generally well tolerated, Miltefosine may cause certain side effects. Most of these are mild to moderate and subside as the body adapts to the medication.\n\nCommon Side Effects\n\nNausea and vomiting\n\nDiarrhea\n\nAbdominal discomfort\n\nLoss of appetite\n\nTemporary weakness or fatigue\n\nModerate Side Effects\n\nElevated liver enzymes\n\nMild kidney function changes\n\nSkin reactions such as redness or itching\n\nSevere, But Less Common Side Effects\n\nNephrotoxicity (kidney-related issues)\n\nHepatotoxicity (liver-related issues)\n\nSevere gastrointestinal upset\n\nVision-related disturbances in very rare cases\n\nImportant Warning for Women\n\nMiltefosine is NOT recommended during pregnancy as it can cause fetal harm. Women of childbearing age must use reliable contraception during treatment and for at least 3 months after therapy.\n\nPrecautions\n\nPatients with the following conditions should use Miltefosine cautiously:\n\nLiver or kidney disease\n\nPregnancy or breastfeeding\n\nSevere dehydration\n\nUncontrolled vomiting or diarrhea\n\nAlways follow the dosage exactly as prescribed by a healthcare professional.\n\nConclusion\n\nMiltefosine Capsules have revolutionized the treatment of various forms of Leishmaniasis by offering a powerful, effective, and convenient oral therapy option. Their ability to target parasitic infections through multiple mechanisms makes them a trusted solution in endemic regions. Whether used for Visceral, Cutaneous, or Mucocutaneous Leishmaniasis, Miltefosine provides significant therapeutic benefits, faster recovery, and improved patient compliance.", "price": 1350.0, "discountamount": 405.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2205, "imageuri": "https://productimages.withfloats.com/actual/6916c0042444cd45b3f0f253.png", "tileimageuri": "https://productimages.withfloats.com/tile/6916c0042444cd45b3f0f253.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-14T05:37:06.048Z", "updatedon": "2025-11-14T05:37:06.048Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/miltefosine-capsules/2205", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MILTEFOSE 50", "category": "GENERAL RANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69142bf71d499513a92e5772", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Nicorandil Tablets 5mg", "description": "Nicorandil Tablets 5 mg is a vasodilatory anti-anginal medication widely prescribed for the management and prevention of angina pectoris (chest pain) associated with coronary artery disease (CAD). Angina results from an imbalance between the heart’s oxygen demand and supply due to restricted blood flow in the coronary arteries. Nicorandil offers a dual mechanism of action — acting both as a nitrate-like vasodilator and a potassium channel opener, making it unique among anti-anginal agents.\n\nBy improving oxygen delivery to the myocardium and reducing cardiac workload, Nicorandil 5 mg Tablets provide effective relief from anginal pain and reduce the frequency and severity of ischemic episodes. It is also beneficial in preventing future attacks, improving exercise tolerance, and enhancing the overall quality of life in patients with chronic stable angina.\n\nComposition\n\nEach tablet contains:\n\nNicorandil IP – 5 mg\n\nExcipients – q.s.\n\nNicorandil tablets are available in film-coated form to ensure stability, easy swallowing, and optimal absorption. They are manufactured in compliance with Good Manufacturing Practices (GMP) standards to ensure safety, purity, and efficacy.\n\nPharmacological Action / Mechanism of Action\n\nNicorandil exhibits a dual mechanism that makes it distinct among anti-anginal drugs:\n\nNitrate-Like Effect:\nNicorandil acts as a nitric oxide (NO) donor. Nitric oxide activates guanylate cyclase, increasing cyclic GMP (cGMP) levels in vascular smooth muscle. This leads to relaxation of blood vessels, particularly veins and large arteries, thereby reducing preload and afterload on the heart. This nitrate-like activity lowers myocardial oxygen demand.\n\nPotassium Channel Opening Effect:\nNicorandil opens ATP-sensitive potassium (KATP) channels in vascular smooth muscle, resulting in arteriolar vasodilation. This increases coronary blood flow and improves oxygen supply to ischemic heart tissues.\n\nTogether, these effects reduce cardiac workload, enhance coronary perfusion, and prevent anginal pain by correcting the oxygen supply-demand mismatch in the heart muscle.\n\nUses and Indications\n\nNicorandil Tablets 5 mg are indicated for the treatment and prevention of angina pectoris in adults, particularly:\n\nChronic Stable Angina:\n\nHelps reduce the frequency and severity of chest pain associated with exertion or emotional stress.\n\nProphylaxis of Angina Attacks:\n\nUsed regularly to prevent anginal episodes, especially in patients with known coronary artery disease.\n\nAdjunct Therapy in Ischemic Heart Disease (IHD):\n\nCan be used alongside beta-blockers, calcium channel blockers, or antiplatelet drugs for enhanced symptom control and long-term protection.\n\nImprovement of Exercise Tolerance:\n\nReduces the likelihood of anginal pain during physical activity, enabling patients to perform daily tasks comfortably.\n\nIn some clinical cases, Nicorandil is also considered for post-myocardial infarction recovery, as it improves coronary perfusion, although this is at the discretion of a cardiologist.\n\nDosage and Administration\n\nRecommended Starting Dose: 5 mg to 10 mg twice daily.\n\nMaintenance Dose: May be increased gradually to 10–20 mg twice daily, depending on clinical response and tolerance.\n\nThe tablets should be swallowed whole with water, preferably at the same times each day.\n\nNicorandil should not be stopped abruptly; dosage tapering is recommended to avoid rebound angina.\n\nAlways follow the dosage instructions provided by the physician.\n\nKey Benefits\n\nDual Mechanism for Comprehensive Relief:\nCombines nitrate-like and potassium channel-opening properties for both arterial and venous dilation, providing superior protection against anginal attacks.\n\nImproves Coronary Blood Flow:\nDilates coronary arteries, increasing oxygen delivery to ischemic myocardial tissues.\n\nReduces Cardiac Workload:\nBy decreasing preload (venous return) and afterload (arterial resistance), Nicorandil minimizes the heart’s oxygen consumption.\n\nRapid Onset of Action:\nNicorandil acts within a short duration, offering quick relief from anginal discomfort.\n\nPrevents Future Angina Episodes:\nRegular use helps maintain steady control of chest pain, improving exercise capacity and quality of life.\n\nCompatible with Other Cardiac Medications:\nCan be safely used alongside antiplatelet agents, beta-blockers, ACE inhibitors, and statins as part of comprehensive cardiac care.\n\nFavorable Safety Profile:\nCompared to nitrates, Nicorandil carries a lower risk of tolerance development, making it suitable for long-term therapy.\n\nEnhances Myocardial Protection:\nNicorandil’s KATP channel activation provides additional cardioprotective effects by improving microvascular blood flow and limiting ischemic damage during stress.\n\nPrecautions and Warnings\n\nAlthough Nicorandil is generally well-tolerated, certain precautions are advised:\n\nHypotension:\nNicorandil may cause a drop in blood pressure due to vasodilation. Caution is advised in patients with hypotension or dehydration.\n\nConcurrent Use with Nitrates:\nShould not be used together with other nitrate medications to avoid severe hypotension.\n\nOral or Gastrointestinal Ulcers:\nRarely, Nicorandil may cause ulcerations in the mouth, intestines, or skin. Treatment should be discontinued if ulceration occurs.\n\nPatients with Low Blood Volume:\nUse cautiously in individuals with hypovolemia or those on diuretics.\n\nDriving and Machinery:\nDizziness or light-headedness may occur; avoid driving until effects are known.\n\nPregnancy and Lactation:\nShould be used only if prescribed by a physician when the potential benefits outweigh the risks.\n\nPossible Side Effects\n\nNicorandil is generally safe but may cause some side effects, particularly at the start of therapy or with higher doses. Common and rare adverse reactions include:\n\nCommon Side Effects:\n\nHeadache (due to vasodilation)\n\nFlushing or warmth sensation\n\nDizziness or light-headedness\n\nNausea or mild stomach upset\n\nFatigue or weakness\n\nLess Common / Rare Side Effects:\n\nHypotension (low blood pressure)\n\nPalpitations or tachycardia\n\nMouth ulcers, anal ulcers, or skin ulceration (uncommon but serious — discontinue if occurs)\n\nRash or allergic reaction\n\nVisual disturbances (rare and usually reversible)\n\nIf any severe reaction or persistent discomfort occurs, medical attention should be sought promptly.\n\nDrug Interactions\n\nAvoid concomitant use with nitrates or phosphodiesterase type-5 inhibitors (e.g., Sildenafil, Tadalafil), as it may cause a dangerous fall in blood pressure.\n\nCaution with antihypertensive drugs or diuretics, which may enhance hypotensive effects.\n\nAlcohol consumption can potentiate dizziness or hypotension and should be limited.\n\nStorage and Handling\n\nStore below 30°C, protected from moisture and direct sunlight.\n\nKeep out of reach of children.\n\nDo not use tablets past the expiry date or if the packaging is damaged.\n\nConclusion\n\nNicorandil Tablets 5 mg offer a modern and effective approach to managing angina pectoris, providing reliable relief through their dual-action mechanism. By combining nitrate-like vasodilation with potassium channel opening, Nicorandil ensures both oxygen supply improvement and reduction of cardiac workload — the cornerstone of angina management.\n\nIt is well-tolerated, fast-acting, and suitable for long-term therapy, making it a preferred choice for patients with chronic stable angina. Regular use under medical supervision helps reduce the frequency of chest pain, improve physical endurance, and enhance the overall quality of life in individuals with coronary artery disease.", "price": 381.0, "discountamount": 115.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2202, "imageuri": "https://productimages.withfloats.com/actual/69142c03b53db80943abd33d.png", "tileimageuri": "https://productimages.withfloats.com/tile/69142c03b53db80943abd33d.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-12T06:40:55.795Z", "updatedon": "2025-11-12T06:40:55.795Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/nicorandil-tablets-5mg/2202", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Steris Healthcare Pvt Ltd", "category": "CARDIOLOGYRANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6911af10f122e2a45d230b07", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Sitagliptin 50 mg, Metformin Hydrochloride 1000 mg & Glimepirde 2 mg", "description": "Sitagliptin 50 mg, Metformin Hydrochloride 1000 mg, and Glimepiride 2 mg is a triple-combination oral anti-diabetic medication formulated to achieve optimal blood sugar control in adults with Type 2 Diabetes Mellitus (T2DM). This unique blend brings together three complementary agents — Sitagliptin (a DPP-4 inhibitor), Metformin (a biguanide), and Glimepiride (a sulfonylurea) — that work through distinct mechanisms to enhance glucose regulation, improve insulin sensitivity, and support overall metabolic balance.\n\nThis advanced combination therapy is prescribed when monotherapy or dual therapy fails to achieve adequate glycemic control. It helps reduce both fasting plasma glucose (FPG) and postprandial glucose (PPG) levels, promoting stable long-term glycemic management.\n\nUses of Sitagliptin + Metformin + Glimepiride\n\nThis fixed-dose combination is primarily indicated for the management of Type 2 Diabetes Mellitus in adults. It is especially beneficial for patients whose blood sugar levels remain uncontrolled despite treatment with Metformin and Glimepiride or Metformin and Sitagliptin alone.\n\nIts main objectives include:\n\nControlling elevated blood glucose levels in adults with Type 2 diabetes\n\nReducing the risk of diabetes-related complications such as neuropathy, nephropathy, and cardiovascular diseases\n\nSupporting better insulin utilization by the body\n\nComplementing diet, exercise, and lifestyle modification to maintain optimal glycemic balance\n\nMechanism of Action\n\nEach component of this combination plays a vital role in maintaining blood sugar control:\n\nSitagliptin (50 mg) – A Dipeptidyl Peptidase-4 (DPP-4) inhibitor that enhances the activity of incretin hormones. These hormones stimulate insulin release and suppress glucagon production when blood glucose levels rise, thereby improving post-meal glucose control.\n\nMetformin Hydrochloride (1000 mg) – A biguanide that lowers glucose production in the liver and increases the body’s sensitivity to insulin. It also decreases intestinal glucose absorption, making it an essential first-line therapy in diabetes management.\n\nGlimepiride (2 mg) – A sulfonylurea that stimulates pancreatic beta cells to release more insulin, especially when blood glucose levels are high. It works synergistically with Metformin and Sitagliptin for more effective glycemic control.\n\nKey Benefits\n\nTriple Mechanism for Superior Control:\nBy combining three potent agents, the medication addresses multiple pathways of glucose regulation—insulin secretion, insulin sensitivity, and hepatic glucose output—resulting in comprehensive and consistent control of blood sugar levels.\n\nEffective Glycemic Stability:\nThe combination helps maintain target HbA1c levels and reduces both fasting and post-meal glucose spikes without significant weight gain when used with proper diet and exercise.\n\nReduced Risk of Diabetic Complications:\nLong-term blood sugar control minimizes the risk of complications such as kidney disease, vision problems, nerve damage, and heart conditions associated with uncontrolled diabetes.\n\nConvenient Fixed-Dose Formulation:\nCombining three medications into a single tablet simplifies dosing schedules, improves patient adherence, and reduces pill burden, which is crucial for long-term treatment success.\n\nImproved Insulin Efficiency:\nEnhances the body's natural insulin response and glucose metabolism, allowing for smoother daily energy levels and reduced fatigue associated with hyperglycemia.\n\nPossible Side Effects\n\nWhile this combination is generally well tolerated, some patients may experience side effects, especially at the beginning of therapy. Common and rare side effects include:\n\nHypoglycemia (low blood sugar): More likely when meals are skipped or during excessive physical exertion. Symptoms include sweating, dizziness, and rapid heartbeat.\n\nGastrointestinal disturbances: Such as nausea, vomiting, diarrhea, abdominal discomfort, or loss of appetite (mostly due to Metformin).\n\nHeadache or Weakness: Usually mild and transient.\n\nAllergic reactions: Rarely, rash or itching may occur.\n\nLactic Acidosis (rare but serious): A potential complication of Metformin, particularly in patients with kidney impairment or excessive alcohol consumption.\n\nWeight gain: Mild weight gain may occur due to Glimepiride’s insulin-enhancing effect.\n\nPrecautions:\n\nRegular monitoring of blood sugar levels and kidney function is essential.\n\nAvoid alcohol and consult a doctor before using this medicine if you have liver or kidney disease.\n\nThe medication should not be used in patients with Type 1 diabetes or diabetic ketoacidosis.\n\nConclusion\n\nThe combination of Sitagliptin 50 mg, Metformin Hydrochloride 1000 mg, and Glimepiride 2 mg represents a powerful and balanced therapy for adults with Type 2 Diabetes Mellitus, especially those requiring triple-drug intervention to achieve desired glycemic control. 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