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{ "products": [ { "_id": "6a43bee2d208c802be053f9d", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Sitagliptin 100mg Metformin Hydrochloride 1000mg Sustained Release Pioglitazone 15 mg", "description": "Managing type 2 diabetes often requires more than a single medication to achieve long-term blood sugar control. Sitagliptin 100mg Metformin Hydrochloride 1000mg Sustained Release Pioglitazone 15 mg is a triple-combination prescription medicine formulated to help adults with type 2 diabetes maintain healthy glucose levels when diet, exercise, and single-drug therapy are not enough.\n\nThis advanced combination works through three different mechanisms to improve insulin sensitivity, reduce glucose production by the liver, and enhance the body's natural insulin response after meals. Because of its multi-action approach, it is frequently prescribed by healthcare professionals for patients requiring comprehensive glycemic control.\n\nIf you are searching for Sitagliptin 100mg Metformin Hydrochloride 1000mg Sustained Release Pioglitazone 15 mg, this guide covers everything you need to know—including how it works, benefits, dosage information, side effects, precautions, storage, and frequently asked questions.\n\nWhat is Sitagliptin 100mg Metformin Hydrochloride 1000mg Sustained Release Pioglitazone 15 mg?\n\nSitagliptin 100mg Metformin Hydrochloride 1000mg Sustained Release Pioglitazone 15 mg is a prescription oral anti-diabetic medicine used to manage Type 2 Diabetes Mellitus. It combines three clinically proven medicines into one convenient tablet to provide better blood sugar management throughout the day.\n\nThe formulation contains:\n\nSitagliptin 100 mg – A DPP-4 inhibitor that increases incretin hormones to improve insulin secretion.\nMetformin Hydrochloride 1000 mg Sustained Release – A biguanide that lowers glucose production by the liver and improves insulin sensitivity.\nPioglitazone 15 mg – A thiazolidinedione that enhances the body's response to insulin.\n\nTogether, these ingredients target multiple causes of high blood sugar, helping patients achieve better diabetes control while reducing the need for multiple separate medications.\n\nHow Does Sitagliptin 100mg Metformin Hydrochloride 1000mg Sustained Release Pioglitazone 15 mg Work?\n\nThis triple-combination tablet works through complementary mechanisms:\n\n1. Sitagliptin\n\nSitagliptin inhibits the DPP-4 enzyme, allowing incretin hormones to remain active longer. These hormones increase insulin release after meals and reduce excess glucagon production.\n\n2. Metformin SR\n\nMetformin Sustained Release decreases glucose production in the liver, reduces intestinal glucose absorption, and improves insulin sensitivity without causing excessive insulin release.\n\n3. Pioglitazone\n\nPioglitazone improves insulin sensitivity in muscle and fat tissues, enabling cells to utilize glucose more effectively.\n\nThe combination helps maintain consistent blood sugar levels throughout the day while lowering both fasting and post-meal glucose.\n\nWhy is This Triple Combination Important?\n\nType 2 diabetes progresses over time, making it difficult for many patients to control blood sugar using a single medication. A triple therapy offers several advantages:\n\nBetter HbA1c reduction\nMultiple mechanisms of action\nReduced insulin resistance\nImproved post-meal glucose control\nLower fasting blood sugar\nSimplified treatment with one tablet\nImproved medication adherence\nReduced need for additional medications\n\nHealthcare providers often prescribe this combination when dual therapy no longer provides adequate glucose control.\n\nKey Benefits of Sitagliptin 100mg Metformin Hydrochloride 1000mg Sustained Release Pioglitazone 15 mg\nExcellent Blood Sugar Control\n\nThe medicine helps reduce both fasting and postprandial blood glucose levels effectively.\n\nTriple Mechanism of Action\n\nEach ingredient targets a different pathway involved in diabetes, resulting in more comprehensive glycemic control.\n\nImproved Insulin Sensitivity\n\nPioglitazone increases insulin responsiveness, helping the body utilize glucose more efficiently.\n\nReduced Liver Glucose Production\n\nMetformin decreases glucose release from the liver, preventing unnecessary increases in blood sugar.\n\nSupports Long-Term Diabetes Management\n\nRegular use, alongside lifestyle modifications, contributes to improved HbA1c levels and reduced diabetes-related complications.\n\nConvenient Once-Daily Regimen\n\nCombining three medicines into a single tablet improves treatment convenience and supports better compliance.\n\nWho May Benefit from This Medicine?\n\nHealthcare professionals may prescribe this medication for adults with Type 2 Diabetes who:\n\nHave uncontrolled blood sugar despite dual therapy\nRequire triple oral anti-diabetic therapy\nHave elevated HbA1c levels\nNeed improved insulin sensitivity\nPrefer fewer tablets in their treatment plan\nAre following dietary and exercise recommendations but require additional glucose control\n\nThis medicine is not intended for Type 1 Diabetes or diabetic ketoacidosis.\n\nHow to Take Sitagliptin 100mg Metformin Hydrochloride 1000mg Sustained Release Pioglitazone 15 mg\n\nAlways follow your physician's instructions.\n\nGeneral recommendations include:\n\nTake once daily or as prescribed.\nSwallow the tablet whole.\nDo not crush, split, or chew the sustained-release tablet.\nTake with food to reduce stomach discomfort.\nTake it at the same time each day.\nContinue exercising and following a diabetic meal plan.\n\nNever stop treatment without consulting your healthcare provider.\n\nPossible Side Effects\n\nLike all prescription medicines, this combination may cause side effects, although not everyone experiences them.\n\nCommon side effects include:\n\nNausea\nStomach discomfort\nDiarrhea\nHeadache\nUpper respiratory infection\nWeight gain\nSwelling of feet or ankles\nMuscle aches\nDizziness\n\nSeek immediate medical attention if you experience:\n\nSevere allergic reaction\nPersistent vomiting\nDifficulty breathing\nSevere abdominal pain\nUnusual fatigue\nYellowing of skin or eyes\nSymptoms of lactic acidosis\nSigns of heart failure, such as rapid weight gain or shortness of breath\nPrecautions Before Using This Medicine\n\nInform your healthcare provider if you have:\n\nKidney disease\nLiver disease\nHeart failure\nBladder cancer history\nPancreatitis\nSevere dehydration\nAlcohol dependence\nVitamin B12 deficiency\nPlanned surgery or imaging with contrast dye\n\nWomen who are pregnant or breastfeeding should use this medicine only under medical supervision.\n\nDrug Interactions\n\nTell your doctor about all medicines you take, including:\n\nInsulin\nSulfonylureas\nDiuretics\nCorticosteroids\nThyroid medicines\nBlood pressure medicines\nRifampicin\nAlcohol\nCimetidine\nCertain antifungal medicines\n\nProper medication review helps minimize interaction risks.\n\nLifestyle Tips for Better Diabetes Control\n\nMedicine works best when combined with healthy lifestyle habits.\n\nRecommended practices include:\n\nFollow a balanced diabetic diet.\nExercise for at least 30 minutes most days.\nMonitor blood sugar regularly.\nMaintain a healthy body weight.\nStay hydrated.\nAvoid smoking.\nLimit alcohol intake.\nGet regular HbA1c tests.\nManage stress effectively.\nAttend routine medical check-ups.\nStorage Instructions\n\nStore the tablets:\n\nBelow 25°C\nIn a cool, dry place\nAway from moisture and direct sunlight\nIn the original packaging\nOut of reach of children and pets\n\nDo not use expired medicine.\n\nWhy Healthcare Professionals Choose This Triple Combination\n\nDoctors frequently recommend Sitagliptin 100mg Metformin Hydrochloride 1000mg Sustained Release Pioglitazone 15 mg because it addresses multiple aspects of diabetes management in a single formulation. By improving insulin secretion, reducing hepatic glucose production, and enhancing insulin sensitivity, it provides comprehensive glycemic control while simplifying treatment. When combined with a healthy lifestyle and regular medical follow-up, it can support long-term diabetes management and help reduce the risk of complications associated with uncontrolled blood sugar.\n\nConclusion\n\nSitagliptin 100mg Metformin Hydrochloride 1000mg Sustained Release Pioglitazone 15 mg is an effective prescription medication designed for adults with Type 2 Diabetes Mellitus who require stronger blood sugar management than single or dual therapy can provide. Its triple-action formula offers improved glycemic control, better insulin utilization, and convenient once-daily dosing. While highly effective, it should always be used under the guidance of a qualified healthcare professional, together with a balanced diet, regular physical activity, and routine blood sugar monitoring for the best long-term outcomes.\n\nHigh-Ranking FAQs (Google Search & Voice Search Optimized)\n1. What is Sitagliptin 100mg Metformin Hydrochloride 1000mg Sustained Release Pioglitazone 15 mg used for?\n\nIt is prescribed to help adults with Type 2 Diabetes Mellitus control blood sugar when lifestyle changes and other oral medicines do not provide adequate glycemic control.\n\n2. How does this triple-combination tablet work?\n\nIt combines three medicines that increase insulin release after meals, reduce glucose production by the liver, and improve the body's sensitivity to insulin, resulting in better overall blood sugar control.\n\n3. Can this medicine be taken once daily?\n\nYes. Many patients take it once daily, but the exact dosage and timing should always follow the prescribing doctor's instructions.\n\n4. Should I take this tablet with food?\n\nYes. Taking it with meals helps reduce stomach-related side effects associated with metformin and improves tolerability.\n\n5. Can this medicine cure diabetes?\n\nNo. It helps control blood sugar levels but does not cure Type 2 Diabetes. Long-term treatment, healthy eating, exercise, and regular monitoring remain essential.\n\n6. What should I do if I miss a dose?\n\nTake the missed dose as soon as you remember unless it is nearly time for your next scheduled dose. Do not take two doses together to make up for a missed dose.\n\n7. Can this medicine cause low blood sugar?\n\nOn its own, the risk is relatively low. However, the likelihood increases when it is used with insulin or sulfonylurea medicines, or if meals are skipped.\n\n8. Is this medicine safe for patients with kidney disease?\n\nPatients with kidney impairment require medical evaluation before using this medicine, particularly because metformin may not be suitable in severe kidney dysfunction.\n\n9. Can I drink alcohol while taking this medication?\n\nAlcohol intake should be limited or avoided, as excessive consumption may increase the risk of serious side effects, including lactic acidosis.\n\n10. Who should not use Sitagliptin 100mg Metformin Hydrochloride 1000mg Sustained Release Pioglitazone 15 mg?\n\nIt should not be used without medical advice by individuals with Type 1 Diabetes, diabetic ketoacidosis, severe kidney disease, certain liver conditions, or a history of serious hypersensitivity to any of its ingredients. Always consult your healthcare provider before starting treatment.", "price": 243.0, "discountamount": 73.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2462, "imageuri": "https://productimages.withfloats.com/actual/6a43bee3de301bd6de277db2.png", "tileimageuri": "https://productimages.withfloats.com/tile/6a43bee3de301bd6de277db2.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-06-30T13:04:34Z", "updatedon": "2026-06-30T13:04:34Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/sitagliptin-100mg-metformin-hydrochloride-1000mg-sustained-release-pioglitazone-15-mg/2462", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "ST GLIPTIN 3D 1000", "category": "DIABETIC RANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69d4f4af8538099a3d49a36b", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Dapagliflozin 10 mg,Teneligliptin 20 mg & Metformin Hydrochloride 500 mg (Extended Release) Tablets", "description": "Managing type 2 diabetes effectively requires a combination of the right medication, lifestyle changes, and continuous monitoring. GLIDAPA TENMET 500, a powerful triple-combination tablet containing Dapagliflozin (10 mg), Teneligliptin (20 mg), and Metformin Hydrochloride (500 mg), is designed to provide comprehensive glycemic control for individuals suffering from type 2 diabetes mellitus.\n\nThis advanced formulation works through multiple mechanisms to regulate blood sugar levels, improve insulin sensitivity, and reduce glucose production, making it an ideal solution for patients who require combination therapy.\n\nHow GLIDAPA TENMET 500 Works\n\nGLIDAPA TENMET 500 combines three well-established antidiabetic agents, each targeting different pathways:\n\nDapagliflozin works by inhibiting SGLT2 receptors in the kidneys, promoting the excretion of excess glucose through urine.\nTeneligliptin increases incretin hormone levels, which stimulate insulin secretion and decrease glucagon release after meals.\nMetformin Hydrochloride reduces hepatic glucose production and improves insulin sensitivity in peripheral tissues.\n\nTogether, this triple-action formula ensures better blood sugar control throughout the day, especially for patients with uncontrolled diabetes on monotherapy.\n\nUses of GLIDAPA TENMET 500\n\nGLIDAPA TENMET 500 is primarily prescribed for:\n\nManagement of Type 2 Diabetes Mellitus\nPatients with inadequate glycemic control on dual therapy\nReducing fasting and postprandial blood glucose levels\nImproving insulin sensitivity\nSupporting weight management in diabetic patients\n\nIt is usually recommended along with a proper diet and regular exercise for optimal results.\n\nKey Benefits of GLIDAPA TENMET 500\n1. Triple Mechanism Action\n\nUnlike single or dual therapy drugs, this combination provides a three-way approach to diabetes control, targeting different physiological processes.\n\n2. Effective Blood Sugar Control\n\nIt helps maintain stable glucose levels throughout the day, reducing spikes after meals.\n\n3. Weight Management Support\n\nDapagliflozin aids in calorie loss through urine, which may help in weight reduction.\n\n4. Cardiovascular Benefits\n\nThis combination may help reduce cardiovascular risks associated with diabetes when used under medical supervision.\n\n5. Low Risk of Hypoglycemia\n\nCompared to some other antidiabetic medications, it has a relatively lower risk of causing dangerously low blood sugar levels.\n\n6. Improved Patient Compliance\n\nCombining three drugs in one tablet reduces pill burden and improves adherence.\n\nDosage and Administration\nTake GLIDAPA TENMET 500 as prescribed by your doctor\nUsually taken once daily with meals to reduce gastrointestinal side effects\nSwallow the tablet whole; do not crush or chew\nFollow your physician’s advice strictly for best results\nSide Effects of GLIDAPA TENMET 500\n\nLike all medications, this combination may cause some side effects. Most are mild and temporary.\n\nCommon Side Effects\nNausea or vomiting\nDiarrhea\nHeadache\nIncreased urination\nNasopharyngitis (cold-like symptoms)\nMild dehydration\nSerious Side Effects (Rare)\nUrinary tract infections\nGenital infections\nLactic acidosis (rare but serious, linked to Metformin)\nHypoglycemia (especially if combined with other medications)\nKidney function changes\n\nIf any severe symptoms occur, immediate medical attention is necessary.\n\nPrecautions and Warnings\nNot recommended for patients with severe kidney disease\nUse cautiously in elderly patients\nAvoid excessive alcohol consumption\nInform your doctor if you have liver, heart, or pancreatic conditions\nNot suitable for type 1 diabetes or diabetic ketoacidosis\n\nPregnant and breastfeeding women should consult a healthcare professional before use.\n\nWho Should Use GLIDAPA TENMET 500?\n\nThis medication is ideal for:\n\nAdults diagnosed with Type 2 Diabetes\nPatients requiring combination therapy\nIndividuals not achieving control with Metformin alone\nOverweight diabetic patients needing additional metabolic benefits\nStorage Instructions\nStore in a cool, dry place\nKeep away from direct sunlight and moisture\nKeep out of reach of children\nConclusion\n\nGLIDAPA TENMET 500 is a modern, highly effective triple-combination therapy designed to provide comprehensive control over type 2 diabetes. With the combined power of Dapagliflozin, Teneligliptin, and Metformin Hydrochloride, it addresses multiple aspects of glucose metabolism, making it a preferred choice for healthcare professionals.\n\nIts benefits go beyond just blood sugar control—it also supports weight management, improves insulin sensitivity, and enhances overall metabolic health. However, like any medication, it should only be used under proper medical supervision to ensure safety and effectiveness.", "price": 182.0, "discountamount": 55.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2369, "imageuri": "https://productimages.withfloats.com/actual/69d4f4b2203d41ae56676abb.png", "tileimageuri": "https://productimages.withfloats.com/tile/69d4f4b2203d41ae56676abb.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-04-07T12:12:31.371Z", "updatedon": "2026-04-14T12:54:05.267Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//dapagliflozin-10-mg-teneligliptin-20-mg-metformin-hydrochloride-500-mg-extended-release-tablets/2369", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "GLIDAPA TENMET 500", "category": "DIABETIC RANGE", "tags": [ "dapagliflozin teneligliptin metformin combination uses", "metformin teneligliptin dapagliflozin tablets for type 2 diabetes", "buy dapagliflozin teneligliptin metformin tablets online India", "dapagliflozin teneligliptin metformin tablet price wholesale", "SGLT2 + DPP4 + Metformin combination tablet supplier", "anti diabetic triple combination tablets wholesale", "riple combination diabetes medicine manufacturer India" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "699bfe45e844b0fb29d2bbad", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Sitagliptin 100 Pioglitazone 15 Metformin 500", "description": "Product Name: ST GLIPTIN 3D 500\nComposition: Sitagliptin 100 mg + Pioglitazone 15 mg + Metformin 500 mg\n\nST GLIPTIN 3D 500 is a scientifically formulated triple-combination oral antidiabetic tablet designed to help manage Type 2 Diabetes Mellitus effectively. This advanced formulation combines the proven benefits of Sitagliptin, Pioglitazone, and Metformin to provide comprehensive glycemic control through three complementary mechanisms of action.\n\nThis triple therapy approach is especially beneficial for patients whose blood glucose levels are not adequately controlled with dual therapy or monotherapy. ST GLIPTIN 3D 500 is developed to address multiple metabolic defects associated with Type 2 diabetes, ensuring better long-term glucose management and improved patient outcomes.\n\nProduct Description\n\nST GLIPTIN 3D 500 is an oral antidiabetic medication that works by targeting different physiological pathways involved in glucose regulation:\n\nSitagliptin 100 mg enhances incretin hormone levels, which increase insulin release and decrease glucagon secretion in a glucose-dependent manner.\n\nPioglitazone 15 mg improves insulin sensitivity in muscle and adipose tissues, allowing the body to use insulin more effectively.\n\nMetformin 500 mg reduces hepatic glucose production and improves peripheral glucose uptake.\n\nBy combining these three well-established agents into a single tablet, ST GLIPTIN 3D 500 simplifies diabetes management while improving adherence and therapeutic efficiency.\n\nUses of ST GLIPTIN 3D 500\n\nST GLIPTIN 3D 500 is primarily indicated for:\n\nManagement of Type 2 Diabetes Mellitus\n\nImproving glycemic control in adults\n\nPatients inadequately controlled on metformin alone\n\nIndividuals requiring triple oral therapy\n\nReducing fasting and postprandial blood glucose levels\n\nSupporting long-term HbA1c reduction\n\nIt is typically prescribed alongside lifestyle modifications such as a healthy diet, regular exercise, and weight management.\n\nHow ST GLIPTIN 3D 500 Works\n\nType 2 diabetes is characterized by insulin resistance, decreased insulin secretion, and excessive hepatic glucose production. ST GLIPTIN 3D 500 addresses all three core defects:\n\nEnhances insulin secretion (Sitagliptin) – Works in a glucose-dependent manner, reducing risk of hypoglycemia.\n\nImproves insulin sensitivity (Pioglitazone) – Helps the body respond better to insulin.\n\nReduces glucose production (Metformin) – Decreases sugar release from the liver.\n\nThis comprehensive mechanism makes ST GLIPTIN 3D 500 a powerful therapeutic option for sustained glycemic control.\n\nKey Benefits of ST GLIPTIN 3D 500\n1. Triple Mechanism Advantage\n\nCombines three different classes of antidiabetic agents for broader and more effective blood sugar management.\n\n2. Improved HbA1c Reduction\n\nHelps significantly lower HbA1c levels when compared to monotherapy.\n\n3. Reduced Pill Burden\n\nThree medications in one tablet improve patient compliance and convenience.\n\n4. Better Postprandial Control\n\nHelps manage blood glucose spikes after meals.\n\n5. Insulin Sensitivity Enhancement\n\nPioglitazone improves peripheral glucose utilization.\n\n6. Lower Risk of Hypoglycemia\n\nSitagliptin works in a glucose-dependent manner, minimizing low blood sugar risk when used appropriately.\n\n7. Suitable for Long-Term Management\n\nDesigned for chronic use under medical supervision.\n\nDosage and Administration\n\nThe dosage should be taken strictly as prescribed by a healthcare professional.\n\nUsually administered once daily with meals to reduce gastrointestinal discomfort.\n\nSwallow the tablet whole with water.\n\nDo not crush or chew unless directed by a doctor.\n\nRegular monitoring of blood glucose and HbA1c levels is recommended during therapy.\n\nPossible Side Effects\n\nLike all medications, ST GLIPTIN 3D 500 may cause side effects, although not everyone experiences them.\n\nCommon Side Effects:\n\nNausea\n\nDiarrhea\n\nStomach discomfort\n\nHeadache\n\nUpper respiratory symptoms\n\nLess Common but Important:\n\nWeight gain (associated with Pioglitazone)\n\nFluid retention or edema\n\nLow blood sugar (when combined with other antidiabetic agents)\n\nVitamin B12 deficiency (long-term Metformin use)\n\nRare but Serious:\n\nLactic acidosis (rare, associated with Metformin)\n\nPancreatitis (rare, associated with Sitagliptin)\n\nLiver function abnormalities\n\nPatients should immediately consult a healthcare provider if they experience severe abdominal pain, persistent vomiting, unusual swelling, or breathing difficulties.\n\nPrecautions and Warnings\n\nNot recommended for Type 1 diabetes.\n\nUse cautiously in patients with renal impairment.\n\nLiver function monitoring may be required.\n\nAvoid excessive alcohol consumption.\n\nInform your doctor about any existing heart conditions.\n\nPregnant or breastfeeding women should use this medication only if clearly advised by a healthcare professional.\n\nStorage Instructions\n\nStore below 25°C in a dry place.\n\nKeep away from direct sunlight.\n\nKeep out of reach of children.\n\nWhy Choose ST GLIPTIN 3D 500?\n\nST GLIPTIN 3D 500 stands out as a comprehensive diabetes management solution by combining three powerful and clinically established molecules in one convenient tablet. It is particularly beneficial for patients who require intensified glycemic control without increasing pill burden.\n\nThe triple therapy model helps target multiple metabolic dysfunctions simultaneously, offering better blood glucose stability throughout the day. When used as part of a complete diabetes management plan—including diet, exercise, and routine monitoring—ST GLIPTIN 3D 500 can significantly enhance quality of life and reduce long-term complications associated with uncontrolled diabetes.\n\nConclusion\nST GLIPTIN 3D 500 (Sitagliptin 100 mg + Pioglitazone 15 mg + Metformin 500 mg) represents a modern, evidence-based approach to managing Type 2 Diabetes Mellitus. By addressing insulin resistance, impaired insulin secretion, and excessive glucose production, it provides comprehensive and sustained glycemic control.", "price": 222.0, "discountamount": 67.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2311, "imageuri": "https://productimages.withfloats.com/actual/699bfe47d849febb9bcc2d46.png", "tileimageuri": "https://productimages.withfloats.com/tile/699bfe47d849febb9bcc2d46.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-02-23T07:14:13.494Z", "updatedon": "2026-03-13T11:04:02.141Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//sitagliptin-100-pioglitazone-15-metformin-500/2311", "availableunits": -1.0, "iscodavailable": true, "isprepaidonlineavailable": true, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "ST GLIPTIN 3D 500", "category": "DIABETIC RANGE", "tags": [ "Sitagliptin 100 Pioglitazone 15 Metformin 500 tablet uses", "Sitagliptin Pioglitazone Metformin triple therapy dosage", "Sitagliptin 100 mg Pioglitazone 15 mg Metformin 500 mg benefits", "Triple combination tablet for type 2 diabetes control", "Sitagliptin Pioglitazone Metformin side effects in adults", "How to take Sitagliptin Pioglitazone Metformin tablet", "Sitagliptin Metformin Pioglitazone price in India", "Buy Sitagliptin 100 Pioglitazone 15 Metformin 500 online", "Order Sitagliptin Pioglitazone Metformin tablets", "Sitagliptin 100 Pioglitazone 15 Metformin 500 price", "Sitagliptin triple combination bulk purchase" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "694e56c05837f90c86a7eb8c", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "empagliflozin linagliptin and metformin", "description": "LINALIGIP EMPAMET (Empagliflozin, Linagliptin, and Metformin Hydrochloride ER Tablets) stands out as a comprehensive triple therapy for adults with type 2 diabetes mellitus, combining three synergistic agents to tackle hyperglycemia from multiple angles. This once-daily extended-release formulation simplifies adherence while delivering robust glycemic control, weight management, and cardiovascular protection. Patients often seek it for its convenience in managing blood sugar levels when diet, exercise, and single agents fall short.\n​\n\nProduct Description and Composition\nLINALIGIP EMPAMET features Empagliflozin (typically 10-25mg), Linagliptin (5 mg), and Metformin Hydrochloride ER (up to 1000mg) in a single tablet, designed for prolonged release to minimize gastrointestinal upset. Empagliflozin, an SGLT2 inhibitor, blocks glucose reabsorption in the kidneys, promoting its excretion via urine. Linagliptin, a DPP-4 inhibitor, enhances incretin hormones like GLP-1 to boost insulin secretion and suppress glucagon. Metformin ER reduces hepatic glucose production and improves insulin sensitivity without hypoglycemia risk.\n​\n\nThis unique blend from Steris Healthcare ensures steady drug delivery over 24 hours, reducing peak-trough fluctuations for stable HbA1c reductions of 1.5-2.0%. The extended-release metformin coats the tablet core, dissolving gradually in the intestines for better tolerability compared to immediate-release forms. Ideal for Indian patients facing rising diabetes prevalence, it addresses insulin resistance, postprandial spikes, and caloric overload holistically.\n​\n\nMechanism of Action\nThe triple mechanism targets key diabetes pathways: Empagliflozin inhibits SGLT2 in proximal renal tubules, lowering blood glucose by 70-90g daily through glycosuria, independent of insulin. Linagliptin selectively binds DPP-4, prolonging GLP-1 and GIP activity to stimulate glucose-dependent insulin release from beta cells and curb glucagon-mediated gluconeogenesis. Metformin activates AMPK in hepatocytes, inhibiting gluconeogenesis while enhancing peripheral glucose uptake.\n​\n\nSynergy amplifies effects—SGLT2 inhibition provides insulin-independent control, DPP-4 boosts prandial responses, and metformin tackles fasting hyperglycemia—resulting in complementary HbA1c drops without overlapping toxicities. Clinical data show this combination yields superior efficacy over dual therapies, with added osmotic diuresis aiding fluid balance.\n​\n\nUses and Indications\nLINALIGIP EMPAMET treats type 2 diabetes in adults, as adjunct to diet and exercise, especially when metformin alone or dual therapy inadequately controls glycemia. Primary uses include newly diagnosed patients needing intensification, those with obesity (due to weight loss from glycosuria), and high-risk cardiovascular profiles benefiting from empagliflozin's heart protection. It excels in managing postprandial hyperglycemia, fasting glucose, and preventing complications like nephropathy.\n​\n\nPrescribed for patients intolerant to other agents or requiring simplified regimens, it suits Indian demographics with high metabolic syndrome rates. Not for type 1 diabetes or ketoacidosis; renal function (eGFR >45 mL/min) guides initiation.\n​\n\nKey Benefits\nLINALIGIP EMPAMET offers multifaceted advantages for long-term diabetes management:\n\nSuperior Glycemic Control: Achieves 1.8% HbA1c reduction in trials, outperforming monotherapies by targeting multiple defects.\n​\n\nWeight Loss: Empagliflozin induces 3-5kg loss via caloric excretion, countering metformin's neutral effect.\n​\n\nCardiovascular and Renal Protection: Reduces major adverse cardiac events (MACE) by 14% and slows CKD progression, per EMPA-REG outcomes.\n​\n\nLow Hypoglycemia Risk: Glucose-dependent actions of linagliptin and empagliflozin minimize lows, unlike sulfonylureas.\n​\n\nConvenience: Single-tablet ER dosing improves compliance, vital for busy lifestyles in Jaipur and beyond.\n​\n\nBlood Pressure Reduction: Mild diuretic effect lowers systolic BP by 3-5 mmHg.\n​\n\nThese benefits enhance quality of life, reducing fatigue, neuropathy risks, and healthcare costs.\n\nSide Effects\nCommon side effects mirror individual components but occur less due to synergy:\n\nGastrointestinal: Metformin ER causes less nausea/diarrhea (10-15%) than IR forms; titrate slowly.\n​\n\nGenitourinary: Empagliflozin raises UTI/genital mycotic infection risk (5-10%), managed with hygiene.\n​\n\nVolume Depletion: Orthostatic hypotension in 2-3%, especially with diuretics.\n​\n\nSerious effects include lactic acidosis (rare, <1/100,000 with metformin in eGFR >30), ketoacidosis (euglycemic, 0.1%), and acute kidney injury. Monitor for dehydration, pancreatitis signs, or bullous pemphigoid with linagliptin. Hypersensitivity rash or bone fractures warrant discontinuation.\n​\n\nSide Effect Category\tFrequency\tManagement\nNausea and Diarrhea\tCommon (10%)\tTake with food, slow titration \n​\nUTI/Mycotic Infections\tCommon (7%)\tHydration, antifungals \n​\nHypoglycemia\tRare (<2%)\tWith insulin, dose adjust \n​\nLactic Acidosis\tVery Rare.\tAvoid in renal/hepatic failure \n​\nKetoacidosis\tRare (0.1%)\tCheck ketones if nausea \n​\nDosage and Administration\nStart with Empagliflozin 10mg/Linagliptin 5mg/Metformin ER 1000mg once daily with morning meal to optimize absorption and reduce GI effects. Titrate metformin to 2000mg max based on tolerance; empagliflozin to 25mg if needed. Swallow whole; no crushing. Adjust for renal impairment (eGFR 30-45: max metformin 1000mg; <30 contraindicated). Elderly start low due to volume sensitivity.\n​\n\nMissed dose: Take soon if less than 12 hours late; skip otherwise. Discontinue pre-surgery or contrast use.\n\nPrecautions and Warnings\nAssess eGFR before and 3-6 months after initiation; hold if <45. Caution in dehydration, heart failure, or liver disease risks lactic acidosis. Educate on ketoacidosis symptoms (nausea, fatigue) despite normal glucose. Avoid excessive alcohol; monitor BP in hypertensives. Pregnancy category D—use insulin instead. Breastfeeding is contraindicated.\n​\n\nDrug interactions: Adding sulfonylureas/insulin heightens hypoglycemia; rifampin reduces linagliptin levels; ritonavir boosts empagliflozin exposure.\n\nFrequently Asked Questions\nWhat is LINALIGIP EMPAMET used for?\nControls type 2 diabetes via triple action on glucose excretion, incretins, and insulin sensitivity.\n​\nDoes it cause weight gain?\nNo—it promotes 2-4 kg loss, unlike some antidiabetics.\n​\n\nSafe for kidneys?\nRenal-protective; monitor eGFR.\n​\n\nHypoglycemia risk?\nMinimal without sulfonylureas.\n\nConclusion\nLINALIGIP EMPAMET revolutionizes type 2 diabetes care with its potent, convenient triple therapy, delivering glycemic mastery, weight benefits, and cardioprotection unmatched by singles or duos. Backed by landmark trials, it empowers patients toward complication-free lives when integrated with lifestyle changes. Consult physicians for personalized dosing to harness its full potential safely.", "price": 220.0, "discountamount": 66.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2257, "imageuri": "https://productimages.withfloats.com/actual/694e60c1db6d50f75e42e875.png", "tileimageuri": "https://productimages.withfloats.com/tile/694e60c1db6d50f75e42e875.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-26T09:34:56.604Z", "updatedon": "2026-03-13T10:59:31Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//empagliflozin-linagliptin-and-metformin/2257", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "LINALIGIP EMPAMET", "category": "DIABETIC RANGE", "tags": [ "empagliflozin 10 mg", "empagliflozin 25 mg", "empagliflozin 10 mg uses in hindi", "empagliflozin 10 mg tablet.", "type 2 diabetes mellitus.", "linagliptin", "Linagliptin 5 mg", "linagliptin 5 mg uses", "linagliptin tablet uses", "Linagliptin 5 mg price", "Empagliflozin, an SGLT2 inhibitor.", "Metformin ER reduces hepatic glucose production and improves insulin.", "LINALIGIP EMPAMET revolutionizes type 2 diabetes.", "empagliflozin linagliptin and metformin tablets", "empagliflozin linagliptin metformin combination tablet", "empagliflozin linagliptin metformin tablets uses", "empagliflozin linagliptin metformin triple combination", "empagliflozin linagliptin metformin dosage strength", "empagliflozin linagliptin metformin sustained release tablet", "empagliflozin linagliptin metformin medicine for diabetes", "empagliflozin linagliptin metformin tablet uses", "empagliflozin linagliptin metformin benefits", "empagliflozin linagliptin metformin for type 2 diabetes", "empagliflozin linagliptin metformin blood sugar control", "empagliflozin linagliptin metformin weight loss benefit", "what is empagliflozin linagliptin metformin tablet", "how does empagliflozin linagliptin metformin work", "empagliflozin linagliptin metformin tablet price in india", "empagliflozin linagliptin metformin tablet dosage", "empagliflozin linagliptin metformin before or after food" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6932959513286b8c66d8786f", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Myoinositol 600mg + Metformin SR 500", "description": "OVOCYST M is a specialized sustained-release tablet combining Myoinositol 600mg and Metformin SR 500mg, primarily designed to address polycystic ovary syndrome (PCOS) and related metabolic issues in women. This formulation from Steris Healthcare Pvt Ltd targets insulin resistance, hormonal imbalances, and ovulatory dysfunction, making it a go-to option for restoring reproductive wellness. By improving insulin sensitivity and ovarian function, OVOCYST M supports regular cycles and fertility outcomes effectively.​\n\nProduct Composition and Mechanism\nOVOCYST M features Myoinositol 600mg, a natural insulin signaling mediator that enhances cellular health and oocyte quality in PCOS patients. Paired with Metformin SR 500mg, a sustained-release biguanide that lowers hepatic glucose production and boosts peripheral insulin uptake, this duo tackles root causes like hyperinsulinemia. The SR technology ensures gradual release, minimizing digestive upset while providing prolonged metabolic support throughout the day.​\n\nThis synergistic action restores ovulatory cycles by balancing hormones such as FSH and LH, reducing androgen excess common in PCOS. Women experiencing anovulation or irregular menses find OVOCYST M particularly beneficial as it promotes follicular development without aggressive interventions.​\n\nKey Uses of OVOCYST M\nOVOCYST M excels in managing PCOS symptoms, including irregular menstrual cycles and infertility linked to insulin resistance. Healthcare providers often prescribe it for hyperandrogenism, where elevated male hormones cause hirsutism or acne, alongside metabolic syndrome features like obesity.​\n\nSupports fertility treatments by improving egg quality and implantation rates in assisted reproduction.​\nAids weight management in PCOS by curbing insulin-driven fat accumulation.​\nRegulates blood sugar in prediabetic women with PCOS, preventing progression to type 2 diabetes.​\nTypically taken once or twice daily with meals, the dosage aligns with physician guidance for optimal results over 4-12 weeks.​\n\nMajor Benefits for PCOS and Beyond\nOne standout advantage of OVOCYST M is its ability to normalize ovulation, with studies showing improved cycle regularity in up to 70-80% of users. By enhancing insulin sensitivity, it reduces hyperinsulinemia, alleviating symptoms like fatigue and cravings that hinder daily life.​\n\nPromotes modest weight loss (2-5kg over months) through better metabolic control, boosting self-esteem and mobility.​\n\nEnhances fertility by maturing oocytes and lowering miscarriage risks in PCOS pregnancies.​\n\nLowers androgen levels, clearing skin issues and reducing unwanted hair growth for aesthetic and emotional relief.​\n\nLong-term use under supervision sustains these gains, fostering holistic health improvements like better energy and mood stability.​\n\nPotential Side Effects and Precautions\nWhile generally well-tolerated, OVOCYST M may cause mild gastrointestinal effects such as nausea, flatulence, or a metallic taste from Metformin. These often subside with time or food intake, thanks to the SR formulation's gentler profile.​\n\nRare but serious risks include lactic acidosis in those with kidney/liver issues, warranting avoidance in such cases. Precautions involve monitoring blood sugar, avoiding during acute illnesses, and consulting doctors if pregnant or breastfeeding.​\n\nCommon: Bloating or diarrhea, manageable by starting low dose.​\n\nConsult promptly for persistent vomiting or weakness.​\n\nConclusion\nOVOCYST M stands as a reliable, science-backed ally for women battling PCOS, insulin resistance, and fertility hurdles through its potent Myoinositol 600mg and Metformin SR 500mg blend. Delivering tangible benefits like restored cycles, weight control, and enhanced conception chances, it empowers proactive reproductive health management. Always pair with lifestyle tweaks like balanced diet and exercise for peak efficacy, and rely on professional oversight for safe, sustained results—transforming challenges into opportunities for vitality.", "price": 257.0, "discountamount": 77.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2233, "imageuri": "https://productimages.withfloats.com/actual/693295fa395d93bf6f980d94.jpg", "tileimageuri": "https://productimages.withfloats.com/tile/693295fa395d93bf6f980d94.jpg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-05T08:19:33.812Z", "updatedon": "2026-03-26T06:02:58.674Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//myoinositol-600mg-metformin-sr-500/2233", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "OVOCYST M", "category": "GYANECOLOGYRANGE", "tags": [ "Myoinositol 600mg and Metformin SR 500mg", "polycystic ovary syndrome (PCOS)", "OVOCYST M supports regular cycles and fertility" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6911af10f122e2a45d230b07", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Sitagliptin 50 mg, Metformin Hydrochloride 1000 mg & Glimepirde 2 mg", "description": "Sitagliptin 50 mg, Metformin Hydrochloride 1000 mg, and Glimepiride 2 mg is a triple-combination oral anti-diabetic medication formulated to achieve optimal blood sugar control in adults with Type 2 Diabetes Mellitus (T2DM). This unique blend brings together three complementary agents — Sitagliptin (a DPP-4 inhibitor), Metformin (a biguanide), and Glimepiride (a sulfonylurea) — that work through distinct mechanisms to enhance glucose regulation, improve insulin sensitivity, and support overall metabolic balance.\n\nThis advanced combination therapy is prescribed when monotherapy or dual therapy fails to achieve adequate glycemic control. It helps reduce both fasting plasma glucose (FPG) and postprandial glucose (PPG) levels, promoting stable long-term glycemic management.\n\nUses of Sitagliptin + Metformin + Glimepiride\n\nThis fixed-dose combination is primarily indicated for the management of Type 2 Diabetes Mellitus in adults. It is especially beneficial for patients whose blood sugar levels remain uncontrolled despite treatment with Metformin and Glimepiride or Metformin and Sitagliptin alone.\n\nIts main objectives include:\n\nControlling elevated blood glucose levels in adults with Type 2 diabetes\n\nReducing the risk of diabetes-related complications such as neuropathy, nephropathy, and cardiovascular diseases\n\nSupporting better insulin utilization by the body\n\nComplementing diet, exercise, and lifestyle modification to maintain optimal glycemic balance\n\nMechanism of Action\n\nEach component of this combination plays a vital role in maintaining blood sugar control:\n\nSitagliptin (50 mg) – A Dipeptidyl Peptidase-4 (DPP-4) inhibitor that enhances the activity of incretin hormones. These hormones stimulate insulin release and suppress glucagon production when blood glucose levels rise, thereby improving post-meal glucose control.\n\nMetformin Hydrochloride (1000 mg) – A biguanide that lowers glucose production in the liver and increases the body’s sensitivity to insulin. It also decreases intestinal glucose absorption, making it an essential first-line therapy in diabetes management.\n\nGlimepiride (2 mg) – A sulfonylurea that stimulates pancreatic beta cells to release more insulin, especially when blood glucose levels are high. It works synergistically with Metformin and Sitagliptin for more effective glycemic control.\n\nKey Benefits\n\nTriple Mechanism for Superior Control:\nBy combining three potent agents, the medication addresses multiple pathways of glucose regulation—insulin secretion, insulin sensitivity, and hepatic glucose output—resulting in comprehensive and consistent control of blood sugar levels.\n\nEffective Glycemic Stability:\nThe combination helps maintain target HbA1c levels and reduces both fasting and post-meal glucose spikes without significant weight gain when used with proper diet and exercise.\n\nReduced Risk of Diabetic Complications:\nLong-term blood sugar control minimizes the risk of complications such as kidney disease, vision problems, nerve damage, and heart conditions associated with uncontrolled diabetes.\n\nConvenient Fixed-Dose Formulation:\nCombining three medications into a single tablet simplifies dosing schedules, improves patient adherence, and reduces pill burden, which is crucial for long-term treatment success.\n\nImproved Insulin Efficiency:\nEnhances the body's natural insulin response and glucose metabolism, allowing for smoother daily energy levels and reduced fatigue associated with hyperglycemia.\n\nPossible Side Effects\n\nWhile this combination is generally well tolerated, some patients may experience side effects, especially at the beginning of therapy. Common and rare side effects include:\n\nHypoglycemia (low blood sugar): More likely when meals are skipped or during excessive physical exertion. Symptoms include sweating, dizziness, and rapid heartbeat.\n\nGastrointestinal disturbances: Such as nausea, vomiting, diarrhea, abdominal discomfort, or loss of appetite (mostly due to Metformin).\n\nHeadache or Weakness: Usually mild and transient.\n\nAllergic reactions: Rarely, rash or itching may occur.\n\nLactic Acidosis (rare but serious): A potential complication of Metformin, particularly in patients with kidney impairment or excessive alcohol consumption.\n\nWeight gain: Mild weight gain may occur due to Glimepiride’s insulin-enhancing effect.\n\nPrecautions:\n\nRegular monitoring of blood sugar levels and kidney function is essential.\n\nAvoid alcohol and consult a doctor before using this medicine if you have liver or kidney disease.\n\nThe medication should not be used in patients with Type 1 diabetes or diabetic ketoacidosis.\n\nConclusion\n\nThe combination of Sitagliptin 50 mg, Metformin Hydrochloride 1000 mg, and Glimepiride 2 mg represents a powerful and balanced therapy for adults with Type 2 Diabetes Mellitus, especially those requiring triple-drug intervention to achieve desired glycemic control. Its multi-targeted approach ensures effective management of both fasting and postprandial glucose levels, thereby improving long-term metabolic health and reducing the risk of complications.", "price": 295.0, "discountamount": 89.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2197, "imageuri": "https://productimages.withfloats.com/actual/6911af137e4c90e1dc453884.png", "tileimageuri": "https://productimages.withfloats.com/tile/6911af137e4c90e1dc453884.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-10T09:23:28.795Z", "updatedon": "2026-03-13T10:41:32.995Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//sitagliptin-50-mg-metformin-hydrochloride-1000-mg-glimepirde-2-mg/2197", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "ST GLIPTIN GM 50+1000+2 ", "category": "DIABETIC RANGE", "tags": [ "Sitagliptin 50 mg, Metformin Hydrochloride 1000 mg, and Glimepiride 2 mg", "anti-diabetic medication", "blood sugar control", "Type 2 Diabetes Mellitus" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "68fcb453ba48b3ee8857fd47", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Sitagliptin Phosphate Monhydrate 64.25 mg, Sitagliptin 50 mg, Metformin Hydrochloride 1000 mg & Glimepirde 1 mg", "description": "ST GLIPTIN GM is a high-quality, fixed-dose combination oral antidiabetic medication containing Sitagliptin 50 mg, Metformin Hydrochloride 1000 mg, and Glimepiride 1 mg. This triple-combination therapy is specifically formulated to provide effective glycemic control in adults with type 2 diabetes mellitus (T2DM) who require multiple agents to achieve adequate blood sugar control.\nST GLIPTIN GM works through complementary mechanisms to target the core pathophysiological defects of T2DM—insulin resistance, impaired insulin secretion, and increased hepatic glucose output—making it an ideal choice for patients requiring intensified therapy.\nKey Indications:\nST GLIPTIN GM is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus when dual therapy with any two of the individual components (Sitagliptin, Metformin, or Glimepiride) does not provide adequate control.\nMechanism of Action:\nSitagliptin (50 mg):\nA Dipeptidyl Peptidase-4 (DPP-4) inhibitor that enhances the levels of active incretin hormones (GLP-1 and GIP), increasing insulin release and decreasing glucagon secretion in a glucose-dependent manner.\nMetformin Hydrochloride (1000 mg):\nA biguanide that improves insulin sensitivity by decreasing hepatic glucose production and enhancing peripheral glucose uptake.\nGlimepiride (1 mg):\nA sulfonylurea that stimulates pancreatic β-cells to secrete insulin, thereby reducing blood glucose levels.\nThe combination targets multiple metabolic pathways to provide synergistic and sustained blood glucose control.\nDosage and Administration:\nRecommended Dose:\nOne tablet daily, preferably with meals to reduce gastrointestinal side effects.\nIndividualization Required:\nDosage should be tailored based on patient response, renal function, and physician assessment.\nRenal Monitoring:\nBaseline and periodic assessment of renal function is advised, particularly due to the metformin component.\nKey Benefits of ST GLIPTIN GM 50/1000/1:\nTriple Mechanism of Action:\nTargets insulin resistance, insufficient insulin secretion, and excessive hepatic glucose production.\nEnhanced Glycemic Control:\nEffective in achieving and maintaining HbA1c targets.\nOnce-Daily Convenience:\nImproves adherence by reducing pill burden in patients requiring combination therapy.\nWeight Neutral to Modest Reduction:\nMetformin and sitagliptin components support weight neutrality.\nLow Hypoglycemia Risk:\nSitagliptin and metformin carry minimal hypoglycemia risk; however, glimepiride may increase the risk—monitor accordingly.\nSafety and Precautions:\nHypoglycemia:\nMay occur, particularly due to the glimepiride component. Educate patients on recognizing and managing low blood sugar.\nLactic Acidosis:\nA rare but serious complication of metformin. Avoid in patients with significant renal impairment or conditions predisposing to hypoxia.\nRenal Function:\nDose adjustment or discontinuation may be needed based on renal function.\nPancreatitis:\nRare reports with DPP-4 inhibitors like sitagliptin. Discontinue if suspected.\nAllergic Reactions:\nDiscontinue use if hypersensitivity reactions occur.\nPossible Side Effects:\nWhile ST GLIPTIN GM is generally well-tolerated, some patients may experience:\nNausea\nDiarrhea\nHeadache\nHypoglycemia (especially in elderly or with missed meals)\nAbdominal discomfort\nUpper respiratory tract infections\nDizziness\nFlatulence\nIf any side effects persist or worsen, seek immediate medical advice.\nStorage Instructions:\nStore at a temperature below 30°C.\nProtect from moisture and direct sunlight.\nKeep out of reach of children.\nWhy Choose ST GLIPTIN GM 50/1000/1?\nST GLIPTIN GM provides a powerful and synergistic combination of three well-established antidiabetic agents in a single, convenient daily dose. It offers a comprehensive approach to managing type 2 diabetes by addressing multiple metabolic abnormalities with a focus on safety, efficacy, and patient compliance. Manufactured under stringent GMP-certified conditions, ST GLIPTIN GM ensures quality, reliability, and therapeutic confidence for both patients and prescribers.", "price": 285.0, "discountamount": 86.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2188, "imageuri": "https://productimages.withfloats.com/actual/68fcb456f31288eaa96accfa.png", "tileimageuri": "https://productimages.withfloats.com/tile/68fcb456f31288eaa96accfa.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-10-25T11:28:19.425Z", "updatedon": "2026-03-13T10:40:20.1Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//sitagliptin-phosphate-monhydrate-64-25-mg-sitagliptin-50-mg-metformin-hydrochloride-1000-mg-glimepirde-1-mg/2188", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "ST GLIPTIN GM 50+1000+1", "category": "DIABETIC RANGE", "tags": [ "Sitagliptin 50 mg", "Sitagliptin 50 mg, Metformin Hydrochloride 1000 mg, and Glimepiride 1 mg", "type 2 diabetes mellitus (T2DM)", "blood sugar control" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "68e7a474f3481c1f16d3b038", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "sitagliptin 50mg glimepiride 2mg metformin 500mg", "description": "Sitagliptin 50mg, Metformin Hydrochloride 500mg & Glimepiride 2mg is a combination oral medication designed for the effective management of type 2 diabetes mellitus. This triple-action formula works synergistically to control blood glucose levels by addressing insulin resistance, enhancing insulin secretion, and regulating post-meal sugar spikes. Ideal for patients who require more than one mechanism to maintain stable blood sugar, this combination is often prescribed when monotherapy or dual therapy is insufficient.\n\nUses\n\nManagement of Type 2 Diabetes Mellitus in adults.\n\nHelps in controlling fasting and postprandial blood glucose levels.\n\nRecommended for patients whose blood sugar is not adequately controlled with a single antidiabetic medicine.\n\nCan be used as part of a comprehensive diabetes management plan, including diet and exercise.\n\nKey Benefits\n\nDual Mechanism Control:\n\nMetformin Hydrochloride reduces hepatic glucose production and improves insulin sensitivity.\n\nGlimepiride stimulates pancreatic beta cells to secrete more insulin.\n\nSitagliptin enhances incretin hormones, leading to better regulation of post-meal glucose levels.\n\nEffective Blood Sugar Management:\nHelps maintain optimal fasting and postprandial glucose levels, reducing the risk of diabetes-related complications.\n\nConvenient Combination Therapy:\nCombines three mechanisms in a single tablet, reducing the pill burden and improving patient compliance.\n\nSupports Overall Health:\nHelps prevent long-term complications such as neuropathy, nephropathy, retinopathy, and cardiovascular risks associated with diabetes.\n\nPossible Side Effects\n\nWhile generally well-tolerated, some patients may experience:\n\nGastrointestinal issues: nausea, vomiting, diarrhea, or abdominal discomfort (mainly from Metformin).\n\nHypoglycemia (low blood sugar): more likely due to Glimepiride; symptoms include dizziness, sweating, or shakiness.\n\nAllergic reactions: rash, itching, or swelling in rare cases.\n\nOther mild effects: headache, fatigue, or minor changes in taste.\n\nNote: Patients should always consult their doctor before starting this combination and report any unusual symptoms immediately.\n\nConclusion\n\nThe Sitagliptin, Metformin Hydrochloride & Glimepiride combination provides a powerful, multi-targeted approach to managing type 2 diabetes. By tackling high blood sugar from different angles, it supports better glucose control, enhances overall quality of life, and reduces the risk of diabetes-related complications. When used alongside proper diet, exercise, and medical guidance, this combination can be a cornerstone in effective diabetes management.", "price": 180.0, "discountamount": 54.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2185, "imageuri": "https://productimages.withfloats.com/actual/68e7a47b040520d37b5e6b34.png", "tileimageuri": "https://productimages.withfloats.com/tile/68e7a47b040520d37b5e6b34.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-10-09T12:03:00.012Z", "updatedon": "2026-03-13T10:48:17.253Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//sitagliptin-50mg-glimepiride-2mg-metformin-500mg/2185", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "ST GLIPTIN GM", "category": "DIABETIC RANGE", "tags": [ "Sitagliptin", "Metformin Hydrochloride", "Glimepiride", "type 2 diabetes mellitus", "sitagliptin 50 mg glimepiride 2 mg metformin 500 mg tablet uses", "sitagliptin glimepiride metformin combination benefits for diabetes", "sitagliptin glimepiride metformin tablet dosage guide", "sitagliptin glimepiride metformin tablets how it works for blood sugar", "sitagliptin glimepiride metformin tablets doctor prescription guide", "buy sitagliptin glimepiride metformin tablets online", "sitagliptin glimepiride metformin tablet price in india", "sitagliptin glimepiride metformin tablets supplier", "sitagliptin glimepiride metformin tablets supplier", "who should take sitagliptin glimepiride metformin tablets", "sitagliptin glimepiride metformin tablets weight loss effect", "sitagliptin glimepiride metformin tablets kidney safety" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "68d51d9a26579f4bc195771a", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "glimepiride voglibose metformin", "description": "GLIMITERIS MV1 0.2 is an advanced fixed-dose combination (FDC) medication designed for adults with Type 2 Diabetes Mellitus (T2DM) who require more than lifestyle modifications or single/dual therapy to maintain optimal blood sugar levels. This innovative formulation brings together the power of three well-established antidiabetic agents—Glimepiride (1 mg), Voglibose (0.2 mg), and Metformin Hydrochloride SR (500 mg)—to provide comprehensive glycemic control.\n\nIt is particularly effective for patients struggling with postprandial hyperglycemia, fasting glucose regulation, and HbA1c reduction, making it a preferred choice in cases of poorly controlled diabetes.\n\n \n\nMechanism of Action\nThe therapeutic benefit of GLIMITERIS MV1 0.2 comes from the unique synergy of its three components, each targeting different aspects of glucose metabolism:\n\n1. Glimepiride (1 mg) – Sulfonylurea\nStimulates insulin secretion by activating pancreatic beta cells.\n\nProvides a long-lasting effect with comparatively lower hypoglycemia risk than older sulfonylureas.\n\nHelps reduce both fasting and postprandial glucose levels.\n\n2. Voglibose (0.2 mg) – Alpha-Glucosidase Inhibitor\nDelays the breakdown and absorption of carbohydrates in the intestine.\n\nMinimizes post-meal glucose spikes (PPBG).\n\nActs locally in the gut and has minimal systemic absorption, which reduces systemic side effects.\n\n3. Metformin Hydrochloride SR (500 mg) – Biguanide\nDecreases hepatic glucose production (gluconeogenesis).\n\nImproves peripheral insulin sensitivity, enhancing glucose uptake in muscles.\n\nDoes not cause hypoglycemia on its own.\n\nThe sustained-release (SR) formulation ensures extended control and reduces gastrointestinal side effects.\n\n \n\nIndications\nGLIMITERIS MV1 0.2 is indicated for:\n\nAdults with Type 2 Diabetes Mellitus.\n\nPatients inadequately controlled with monotherapy or dual therapy.\n\nManagement of fasting and postprandial hyperglycemia.\n\nLong-term HbA1c reduction as part of a comprehensive diabetes care plan.\n\n \n\nKey Benefits\n✅ Comprehensive Blood Sugar Control – Acts on fasting, post-meal, and long-term HbA1c levels.\n✅ Postprandial Spike Management – Voglibose effectively controls carbohydrate-induced sugar surges.\n✅ Reduced Pill Burden – Combines three medicines into a single tablet.\n✅ Lower Hypoglycemia Risk – Metformin and Voglibose balance out Glimepiride’s insulin-secreting effect.\n✅ Weight Management Support – Metformin may promote modest weight loss or prevent weight gain.\n✅ Improved Tolerability – SR formulation of Metformin enhances gastrointestinal comfort.\n\n \n\nDosage and Administration\nRecommended dose: One tablet once or twice daily with meals, or as directed by the physician.\n\nAdministration tips:\n\nTake with the first bite of a main meal to maximize Voglibose’s effect.\n\nSwallow whole with water; do not crush or chew the SR tablet.\n\nDose adjustments: Based on blood sugar monitoring, clinical response, and renal/hepatic function.\n\n \n\nContraindications\nGLIMITERIS MV1 0.2 is not suitable for patients with:\n\nType 1 diabetes or diabetic ketoacidosis.\n\nSevere renal impairment (eGFR <30 mL/min/1.73 m²).\n\nHepatic dysfunction.\n\nSevere gastrointestinal diseases.\n\nHistory of lactic acidosis.\n\nHypersensitivity to Glimepiride, Voglibose, or Metformin.\n\nPregnancy and lactation (unless strictly advised by a physician).\n\n \n\nWarnings and Precautions\nHypoglycemia: Risk is higher when combined with other antidiabetics or with missed meals.\n\nLactic Acidosis: A rare but life-threatening effect of Metformin—renal function monitoring is essential.\n\nGI Side Effects: Voglibose and Metformin may cause bloating, flatulence, or diarrhea (usually temporary).\n\nVitamin B12 Monitoring: Long-term Metformin use may reduce B12 absorption.\n\nLiver and Kidney Function: Regular monitoring is recommended for safe long-term use.\n\n \n\nAdverse Effects\nCommon:\nGlimepiride: Mild hypoglycemia, dizziness, slight weight gain.\n\nVoglibose: Gas, abdominal discomfort, mild diarrhea.\n\nMetformin SR: Nausea, bloating, metallic taste, loose stools.\n\nRare but Serious:\nLactic acidosis (from Metformin).\n\nSevere hypoglycemia (especially if meals are skipped).\n\nAllergic reactions such as rash, itching, or swelling.\n\nElevated liver enzymes.\n\nSeek medical attention if symptoms such as rapid breathing, confusion, severe fatigue, or muscle pain occur.\n\n \n\nDrug Interactions\nIncreased hypoglycemia risk: With insulin, beta-blockers, and sulfonylureas.\n\nReduced Metformin efficacy: With corticosteroids, estrogens, and diuretics.\n\nLactic acidosis risk: Higher with alcohol or iodinated contrast agents. 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