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"name": "Micronized Purified Flavonoid Fraction MPFF Tablets 450mg Diosmin+50mg Hesperidin",
"description": "Product Name: FLAVOSHIELD 500\nActive Ingredients: Micronized Purified Flavonoid Fraction (MPFF) 500mg, containing Diosmin 450mg and Hesperidin 50mg.\nPresentation: Oral Tablets\n\nUnveiling FLAVOSHIELD 500: A Deep Dive into Advanced Venous and Vascular Wellness\nIn the intricate network of the human circulatory system, veins perform the silent, relentless task of returning blood to the heart against gravity. When this system faces strain, it can manifest through discomfort, heaviness, and visible changes that impact both physical well-being and quality of life. Enter FLAVOSHIELD 500, a sophisticated pharmaceutical-grade formulation designed to fortify venous health at its core. Powered by a Micronized Purified Flavonoid Fraction (MPFF)—a precise blend of 450mg Diosmin and 50mg Hesperidin—FLAVOSHIELD 500 represents a pinnacle in venoactive therapy. This comprehensive description explores the product, its mechanism, multifaceted uses, key benefits, safety profile, and its role in a holistic health strategy.\n\nWhat is FLAVOSHIELD 500? The Science of MPFF\nFLAVOSHIELD 500 is not a simple herbal supplement; it is a clinically researched, standardized medical treatment. Its active core, the Micronized Purified Flavonoid Fraction, is derived from citrus fruits but undergoes a specialized purification and micronization process. This technological advancement is crucial:\n\nPurification: Ensures a consistent, high-potency concentration of the active flavonoid molecules, Diosmin and Hesperidin, free from plant impurities.\nMicronization: Reduces the particle size of the flavonoids dramatically, increasing their surface area. This leads to significantly enhanced absorption in the gastrointestinal tract, ensuring that a much higher percentage of the active dose reaches the bloodstream and, ultimately, the target venous tissues. Compared to non-micronized diosmin, MPFF offers up to 30% greater bioavailability, making FLAVOSHIELD 500 a more effective and reliable choice.\nThis synergy of Diosmin and Hesperidin works on multiple physiological pathways to restore venous tone and capillary integrity.\n\nPrimary Uses and Therapeutic Applications\nFLAVOSHIELD 500 is indicated for the management of various stages of chronic venous disorders and related conditions:\n\nChronic Venous Disease (CVD) & Venous Insufficiency: This is the primary use. It alleviates the distressing symptoms stemming from weakened vein walls and faulty valves in the legs. These include:\n\nHeaviness and Fatigue: The pervasive feeling of weight and tiredness in the legs, especially after prolonged standing or sitting.\nPain and Aching: Dull, throbbing, or cramping pain that improves with elevation.\nSwelling (Edema): Reduction of ankle and lower leg swelling caused by fluid leakage from capillaries.\nNocturnal Cramps: Relief from painful muscle spasms that often occur at night.\nHemorrhoidal Disease (Acute and Chronic): MPFF is a cornerstone in hemorrhoid management. It treats acute hemorrhoidal attacks by reducing bleeding, pain, and discharge. For chronic cases, it helps prevent recurrences by decreasing capillary fragility and inflammation in the anal venous plexus.\n\nPost-Phlebitic Syndrome: Following deep vein thrombosis (DVT), patients often suffer from chronic leg swelling, pain, and skin changes. FLAVOSHIELD 500 can be part of the management plan to improve microcirculation and reduce symptoms.\n\nSupport Post-Sclerotherapy or Surgical Procedures: It is commonly used after vein stripping, laser ablation, or sclerotherapy to support healing, reduce postoperative swelling and bruising, and help consolidate results.\n\nKey Benefits and Mechanism of Action: The Multi-Target Approach\nThe efficacy of FLAVOSHIELD 500 stems from its multi-faceted pharmacological actions on the venous and lymphatic systems:\n\nVenotonic Action: It increases venous tone and elasticity by promoting the contraction of smooth muscle in the vein walls. This helps veins propel blood more efficiently upward, reducing pooling and pressure. Think of it as “tightening” slackened venous structures.\n\nCapillary-Protective & Anti-Inflammatory Effects: It strengthens capillary walls (reduces capillary permeability) and inhibits the release of inflammatory mediators (like prostaglandins and leukotrienes). This dual action minimizes the leakage of fluid, proteins, and inflammatory cells into surrounding tissues, thereby directly addressing edema (swelling) and inflammation. This is particularly vital in hemorrhoidal tissue.\n\nLymphatic Enhancement: FLAVOSHIELD 500 has been shown to increase lymphatic drainage by boosting the frequency and intensity of lymphatic contractions. This provides an additional route for removing excess interstitial fluid and proteins, further reducing swelling.\n\nAntioxidant Activity: The flavonoids scavenge harmful free radicals, protecting venous and capillary endothelial cells from oxidative stress, which is a contributing factor in chronic venous disease.\n\nImprovement of Microcirculation: By reducing blood viscosity and inhibiting red blood cell aggregation, it improves blood flow in the smallest vessels, enhancing oxygen delivery and waste removal at the tissue level.\n\nPatient-Centric Benefits:\n\nRapid Symptom Relief: Patients often report a noticeable decrease in leg heaviness and pain within the first few weeks of treatment.\nEnhanced Quality of Life: Restores the ability to stand, walk, and engage in daily activities with greater comfort and less discomfort.\nReduced Reliance on Pain Medication: By addressing the underlying inflammation and pain of venous issues and hemorrhoids, it can decrease the need for NSAIDs.\nComplement to Compression Therapy: Works synergistically with compression stockings, often allowing for better tolerance and compliance with compression wear.\nSide Effects and Safety Profile: What to Expect\nFLAVOSHIELD 500 is generally very well-tolerated, with a low incidence of side effects, which are typically mild and transient. This excellent safety profile is a result of its natural origin and high purification.\n\nCommon Side Effects (Rare and usually mild):\n\nGastrointestinal: Some individuals may experience mild, transient digestive disturbances such as nausea, stomach pain, diarrhea, or heartburn. Taking the tablet with a meal can often mitigate this.\nNeurological: Occasional reports of headache or dizziness.\nAllergic Reactions: Very rare cases of skin rash or itching have been reported.\nImportant Safety Considerations:\n\nPregnancy and Lactation: While no teratogenic effects have been demonstrated, as a precaution, use during pregnancy (especially the first trimester) and breastfeeding should only be under the direct supervision of a physician who has weighed the benefits against potential risks.\nDrug Interactions: No significant pharmacokinetic drug interactions have been formally reported. However, as with any medication, it is prudent to inform your doctor about all other medicines and supplements you are taking.\nContraindications: Hypersensitivity to any of the components (Diosmin, Hesperidin, or excipients in the tablet) is a contraindication.\nCrucial Note: FLAVOSHIELD 500 is a treatment for symptoms and a stabilizer of venous function, not a cure for underlying venous valve incompetence. It does not replace definitive interventional treatments (like ablation or surgery) for advanced varicose veins when they are medically indicated. It is essential to receive a proper diagnosis from a healthcare professional to rule out other causes of leg swelling or pain (e.g., cardiac, renal, or hepatic origin).\n\nConclusion: FLAVOSHIELD 500 – A Cornerstone of Comprehensive Venous Care\nIn conclusion, FLAVOSHIELD 500 stands as a robust, scientifically validated agent in the realm of vascular health. Its advanced MPFF technology, combining 450mg of micronized Diosmin with 50mg of Hesperidin, delivers enhanced bioavailability and a powerful, multi-target action that addresses the root causes of venous discomfort: poor tone, capillary fragility, inflammation, and impaired lymphatic drainage.\n\nWhether battling the daily fatigue of heavy legs, managing the acute distress of a hemorrhoidal flare-up, or supporting recovery after a venous procedure, FLAVOSHIELD 500 offers a reliable and well-tolerated therapeutic option. Its benefits in improving symptoms and quality of life are clear, backed by a strong body of clinical evidence.\n\nHowever, optimal venous health is a holistic endeavor. FLAVOSHIELD 500 should be viewed as the pharmacological cornerstone of a broader management plan. This plan should include:\n\nMedical Supervision: Regular consultation with a vascular specialist or phlebologist.\nLifestyle Modifications: Weight management, regular low-impact exercise (walking, swimming), and elevation of the legs.\nCompression Therapy: The use of medically prescribed compression stockings when recommended.\nDietary Awareness: A fiber-rich diet to prevent constipation and straining.\nBy integrating FLAVOSHIELD 500 into this comprehensive approach, individuals can take proactive control of their venous health, shielding their vitality and comfort from the burdens of venous insufficiency. Always consult your healthcare provider to determine if FLAVOSHIELD 500 is appropriate for your specific condition and to establish the correct dosage and treatment duration.\n\nDisclaimer: This content is for informational purposes only and does not constitute medical advice. Always seek the guidance of a qualified healthcare professional with any questions regarding a medical condition or treatment. Do not delay seeking or disregard professional medical advice based on information contained here.",
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"description": "FLAVONOWN DS 1000 \nMicronized purified Flavonoid Fraction 1000 mg\nIntroduction\nFLAVONOWN DS 1000 is a high-potency dietary supplement formulated to support vascular health, improve venous tone, and alleviate symptoms associated with chronic venous insufficiency (CVI) and hemorrhoidal disease. Each tablet contains 1000 mg of Micronized Purified Flavonoid Fraction (MPFF), primarily composed of Diosmin and Hesperidin. The micronization process enhances the absorption and bioavailability of the flavonoids, ensuring maximum therapeutic benefits.\n\nKey Component and Its Benefits\nMicronized Purified Flavonoid Fraction (MPFF) 1000 mg\nMicronized Purified Flavonoid Fraction is a powerful combination of flavonoids, primarily Diosmin and Hesperidin, known for their vascular benefits:\n\nVascular Health: MPFF strengthens blood vessels, improving their tone and elasticity, which helps in maintaining healthy circulation.\nReduces Inflammation: Flavonoids have anti-inflammatory properties that help reduce inflammation in the veins, alleviating symptoms associated with venous insufficiency and hemorrhoids.\nEnhances Lymphatic Drainage: Improves lymphatic drainage, reducing swelling and discomfort in the legs and other affected areas.\nAntioxidant Properties: Protects blood vessels from oxidative stress and damage caused by free radicals.\nBenefits of FLAVONOWN DS 1000\nSupports Vascular Health\nImproves Venous Tone: Enhances the tone and elasticity of veins, promoting better blood flow and reducing the risk of venous disorders.\nStrengthens Blood Vessels: Provides\nessential support to blood vessels, making them more resilient and less prone to damage.\n\nReduces Symptoms of Venous Insufficiency\nAlleviates Leg Pain and Swelling: Reduces pain, swelling, and heaviness in the legs, common symptoms of chronic venous insufficiency.\nPrevents Varicose Veins: Helps in the prevention and management of varicose veins by improving venous return and reducing venous pressure.\nManages Hemorrhoidal Disease\nReduces Hemorrhoid Symptoms: Alleviates symptoms of hemorrhoids, such as pain, bleeding, and swelling, by reducing inflammation and improving venous tone.\nPromotes Healing: Supports the healing of hemorrhoidal tissue and reduces the frequency of flare-ups.\nHow to Use FLAVONOWN DS 1000\nDosage and Administration\nRecommended Dosage: The typical dosage is one FLAVONOWN DS 1000 tablet taken once or twice daily, as directed by your healthcare provider.\nAdministration: Swallow the tablet whole with a full glass of water. It is best taken with meals to enhance absorption and minimize gastrointestinal discomfort.\nGuidelines for Optimal Use\nConsistent Use: For best results, take FLAVONOWN DS 1000 regularly at the same time each day as prescribed by your healthcare provider.\nMonitor Symptoms: Regularly monitor your symptoms and consult your healthcare provider to ensure the supplement is effectively managing your condition.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488\n BUY NOW\nhttps://www.sterisonline.com/product/flavonown-ds-1000-134306",
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"description": "FLAVONOWN 500 \nMicronized purified Flavonoid Fraction 500 mg\nIntroduction\nFLAVONOWN 500 is a dietary supplement containing 500 mg of Micronized Purified Flavonoid Fraction (MPFF). This formulation is specifically designed to support vascular health, improve venous tone, and reduce symptoms related to chronic venous insufficiency (CVI) and hemorrhoidal disease. The micronization process enhances the absorption and bioavailability of the flavonoids, ensuring maximum therapeutic benefits.\n\nKey Component and Its Benefits\nMicronized Purified Flavonoid Fraction (MPFF) 500 mg\nMicronized Purified Flavonoid Fraction is a combination of powerful flavonoids, primarily Diosmin and Hesperidin, known for their vascular benefits:\n\nVascular Health: MPFF strengthens blood vessels, improving their tone and elasticity, which helps in maintaining healthy circulation.\nReduces Inflammation: Flavonoids have anti-inflammatory properties that help reduce inflammation in the veins, alleviating symptoms associated with venous insufficiency and hemorrhoids.\nEnhances Lymphatic Drainage: Improves lymphatic drainage, reducing swelling and discomfort in the legs and other affected areas.\nAntioxidant Properties: Protects blood vessels from oxidative stress and damage caused by free radicals.\nBenefits of FLAVONOWN 500\nSupports Vascular Health\nImproves Venous Tone: Enhances the tone and elasticity of veins, promoting better blood flow and reducing the risk of venous disorders.\nStrengthens Blood Vessels: Provides essential support to blood vessels, making them more resilient and less prone to damage.\nReduces Symptoms of Venous Insufficiency\nAlleviates Leg Pain and Swelling: Reduces pain, swelling, and heaviness in the legs, common symptoms of chronic venous insufficiency.\nPrevents Varicose Veins: Helps in the prevention and management of varicose veins by improving venous return and reducing venous pressure.\nManages Hemorrhoidal Disease\nReduces Hemorrhoid Symptoms: Alleviates symptoms of hemorrhoids, such as pain, bleeding, and swelling, by reducing inflammation and improving venous tone.\nPromotes Healing: Supports the healing of hemorrhoidal tissue and reduces the frequency of flare-ups.\nHow to Use FLAVONOWN 500\nDosage and Administration\nRecommended Dosage: The typical dosage is one tablet taken once or twice daily, as directed by your healthcare provider.\nAdministration: Swallow the tablet whole with a full glass of water. It is best taken with meals to enhance absorption and minimize gastrointestinal discomfort.\nGuidelines for Optimal Use\nConsistent Use: For best results, take FLAVONOWN 500 regularly at the same time each day as prescribed by your healthcare provider.\nMonitor Symptoms: Regularly monitor your symptoms and consult your healthcare provider to ensure the supplement is effectively managing your condition.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488\n BUY NOW\nhttps://www.sterisonline.com/product/flavonown-500-134222",
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"description": "Eligolux 150 delivers 150mg of elagolix per tablet, formulated as an oral, once-daily option in convenient packs for ongoing therapy. As a non-peptide GnRH receptor antagonist, it selectively suppresses pituitary gonadotropins, reducing ovarian estrogen production without the flare effect of agonists. Ideal for patients with milder symptoms or those prioritizing bone health, this dose minimizes hypoestrogenic risks while targeting endometriotic pain.\n\nTake Eligolux 150 whole with water, with or without food, preferably at the same time daily. Storage requires a cool, dry environment below 30°C, away from children and moisture. Steris Healthcare ensures GMP-compliant manufacturing, making it accessible across India for endometriosis care.\n\nPrimary Uses and Indications\nEligolux 150 primarily treats moderate endometriosis-associated pain, including dysmenorrhea, chronic pelvic discomfort, and dyspareunia. Endometriosis impacts 10% of reproductive-age women, causing ectopic endometrial growth that triggers inflammation and scarring; elagolix 150mg curbs estrogen-driven progression.\n\nPrescribed when NSAIDs or combined pills prove inadequate, it excels in non-severe cases, allowing prolonged use. Emerging evidence supports its role in heavy menstrual bleeding from fibroids, though primary approval focuses on pain relief. Start therapy within the first week of menses for optimal synchronization.\n\nMechanism of Action\nElagolix in Eligolux 150 competitively binds GnRH receptors, dose-dependently inhibiting LH/FSH release. This lowers estradiol by 40-60%—less aggressive than 200mg—halting endometrial tissue proliferation outside the uterus. Peak levels hit in 1 hour, with a 4-6 hour half-life supporting steady-state suppression on QD dosing.\n\nUnlike agonists, no initial hormone surge occurs, preventing worsened pain. Partial estrogen reduction preserves some bone-protective effects, differentiating it from deeper suppression therapies.\n\nKey Benefits\nEligolux 150 shines in clinical responsiveness: phase 3 trials showed 32% dysmenorrhea resolution versus 20% placebo at 6 months, with 50% pain score drops. Quality-of-life gains include better work attendance, sleep, and relationships, per EQ-5D assessments.\n\nExtended 24-month approval suits long-term control, with amenorrhea in 40-50% of users reducing bleeding volume by 70%. Oral ease beats injectables, enhancing adherence at 85% in studies. Lower BMD impact (0.5-1% loss/year) allows safer continuation versus higher doses.\n\nBenefit\tTrial Data\tPatient Impact\nPain Reduction\t32-50% dysmenorrhea-free \n\tDaily activity restoration\nBleeding Control\t70% volume drop \n\tAnemia prevention\nLong-Term Use:\tUp to 24 months \n\tSustained relief\nQoL Improvement\tEQ-5D gains \n\tEmotional well-being\nPotential Side Effects\nVasomotor symptoms dominate: hot flashes (20-30%), headaches (17%), and night sweats (10-15%) emerge early but fade. Nausea (8%), insomnia (7%), and mild depression (5%) affect minorities, with a 70% event rate mostly grade 1.\n\nBMD decline averages -0.9% at the spine after 12 months, monitored via DEXA. Discontinuation hovers at 5-8%.\n\nSide Effect\tIncidence\tMitigation\nHot Flashes\t20-30% \n\tVentilation, timing\nHeadache\t17% \n\tAnalgesics\nBMD Loss\t0.9% \n\tSupplements, scans\nMood Shifts\t5% \n\tMonitoring\nSerious Risks and Management\nSuicidality (0.1-0.5%) demands baseline psych screening; halt if worsening. Liver enzymes rise in 1%, requiring LFTs at 3/6 months. Rare anaphylaxis or thromboembolism prompts immediate cessation. Avoid in osteoporosis or smokers >35.\n\n\nDosage Guidelines\n150 mg once daily for up to 24 months in normal/mild liver function; limit to 6 months in moderate impairment (Child-Pugh B). No titration needed; miss a dose? Resume the next day, no doubling. Pair with 1 g calcium/800 IU vitamin D daily.\n\n\nPrecautions and Contraindications\nPregnancy category X: mandates non-hormonal birth control during and 1 week post-therapy. Screen hepatic/renal function; avoid severe cases. CYP3A interactions (e.g., rifampin reduces efficacy) need dose review. Breastfeeding is contraindicated.\n\nClinical Evidence and Efficacy\nElaris trials (n=1,689) confirmed superiority: co-primary endpoints met with 75% responder rates for pain. 12-month extensions showed persistent efficacy and low rebound. Versus 200mg, 150mg balances tolerability for moderate pain.\n\nConclusion\nEligolux 150 empowers women with moderate endometriosis pain through precise, extended hormonal modulation and proven outcomes. Regular physician oversight maximizes safety and efficacy.\n",
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"description": "Eligolux200 contains 200 mg of elagolix per tablet and is manufactured by Steris Healthcare Pvt Ltd in India as a prescription medication in packs of 3x10 tablets. Elagolix acts as a potent gonadotropin-releasing hormone (GnRH) receptor antagonist, binding competitively to GnRH receptors in the pituitary gland to rapidly reduce estrogen and progesterone levels without the initial flare-\nup seen in agonists. This mechanism starves endometrial-like tissue outside the uterus of hormonal stimulation, shrinking lesions and easing inflammation.\n\n\nAdminister Eligolux200 orally, swallowed whole with water, with or without food, typically starting within 7 days of menstrual onset. Standard dosing for severe cases involves 200mg twice daily for up to 6 months, or 150mg once daily extended to 24 months, adjusted by physicians based on tolerance and response. Store in a cool, dry place away from moisture and light, keeping out of children's reach.\n\n\nPrimary Uses\nEligolux200 targets moderate to severe endometriosis-associated pain, including dysmenorrhea (painful periods), nonmenstrual pelvic pain, and dyspareunia (painful intercourse). Endometriosis affects millions globally, causing tissue similar to the uterine lining to grow ectopically, leading to chronic inflammation, adhesions, and scarring. By dosing flexibly, Eligolux200 suits patients needing stronger suppression for intense symptoms, reducing reliance on opioids or surgery.\n\n\nClinical trials like Elaris EM-I and EM-II showed 75% dysmenorrhea reduction and 50-60% nonmenstrual pain relief at 6-12 months. It also curbs heavy menstrual bleeding in uterine fibroids, offering dual benefits for overlapping conditions. Physicians prescribe it when first-line NSAIDs or oral contraceptives fail, prioritizing non-invasive symptom control.\n\n\nKey Benefits\nEligolix in Eligolux200 delivers rapid pain relief, with significant improvements in daily pain scales within 3 months versus placebo. Women report 47% better composite pelvic pain scores, enhancing daily activities, work productivity, and intimacy. Quality-of-life metrics improve consistently over 24 weeks, including reduced fatigue and better emotional well-being.\n\n\nUnlike injectables, its oral form and dose-dependent estrogen suppression allow titration—lower doses minimize hypoestrogenic effects while higher 200mg dosing tackles severe pain. Studies confirm amenorrhea in 25% of users early on, slashing bleeding days by up to 50%. Long-term data up to 12 months with add-back therapy sustains efficacy, preserving bone health better than monotherapy. Patients regain control, avoiding invasive laparoscopies and reclaiming normalcy.\n\n\nBenefit\tEvidence from Trials'\tImpact on Patients\nDysmenorrhea Reduction:\t75% at 6 months \n\tFewer missed workdays\nNonmenstrual Pain Relief:\t50-60% improvement \n\tEnhanced mobility\nBleeding Control:\t14% bleeding days vs. 24% baseline \n\tImproved hygiene, anemia prevention\nQuality of Life\tSustained over 24 weeks \n\tBetter sleep, relationships\nPotential Side Effects\nCommon side effects of Eligolux200 mirror hypoestrogenic states: hot flashes, night sweats, headache, and nausea, each affecting about 10% of users. These often lessen as the body adjusts, with 69.5% overall adverse event rate over 24 weeks, mostly mild. Mood changes like irritability or depression occur less commonly, warranting mood monitoring.\n\n\nBone mineral density (BMD) loss poses a key concern—200mg twice daily causes -1.5% to -2.4% drops at lumbar spine and hip after 6 months, attenuated with calcium/vitamin D or add-back therapy. Rare serious risks include suicidal thoughts, liver enzyme elevations, or allergic reactions like anaphylaxis. Discontinuation due to events stays low at 4-12%. No deaths are linked directly to treatment in trials.\n\n\nSide Effect Category\tFrequency\tManagement\nVasomotor (Hot Flashes)\t9.9-10% \n\tLifestyle cooling, dose adjustment\nNeurologic (Headache)\t9.9% \n\tHydration, analgesics\nBone Loss\tUp to 2.4% at 6 months \n\tDEXA scans, supplements\nMood Changes\tLess common \n\tPsychiatric screening\nPrecautions and Contraindications\nAvoid Eligolux200 in pregnancy (risk of early loss), known osteoporosis, severe hepatic impairment, or with strong OATP1B1 inhibitors like cyclosporine or gemfibrozil. Women of childbearing age need effective non-hormonal contraception during and 28 days post-therapy, as it impairs recognition of pregnancy via amenorrhea. Not for pediatrics under 18 or geriatrics lacking data.\n\n\nScreen for depression history, liver function, and BMD before starting; monitor quarterly. Drug interactions abound with rifampin (reduces levels) or over 50 others like clarithromycin—inform physicians fully. Breastfeeding lacks safety data; weigh risks. Regular blood/urine tests track efficacy and safety.\n\n\nDosage Guidelines\nInitiate Eligolux200 at 150mg daily for milder cases, escalating to 200mg BID for dyspareunia or severe pain, max 6 months at higher dose. Miss a dose? Take promptly unless near next; never double. Duration caps at 24 months total, with liver-adjusted lower dosing. Pair with add-back for extended use to curb BMD loss.\n\n\nPhysicians tailor based on response: 74-77% complete 6-month trials. Swallow intact; no crushing.\n\n\nClinical Evidence\nPhase III trials (Elaris EM-I/II) randomized 1689 women, proving both doses superior to placebo for co-primary endpoints of dysmenorrhea and nonmenstrual pain. Open-label extensions to 24 weeks maintained gains. A 12-month study with add-back showed persistent relief and <1% additional BMD loss versus placebo. Real-world use echoes this, positioning Eligolix as first oral GnRH antagonist approved for endometriosis.\n\n\nVersus relugolix, Eligolix offers comparable pelvic pain reduction with adjustable dosing. Indian brands like Eligolux200 align with global standards.\n\n\nConclusion\nEligolux200 transforms endometriosis management, delivering substantial pain relief and functional gains through precise hormonal control. Balancing robust benefits against manageable risks like BMD monitoring empowers women toward symptom-free lives. Consult healthcare providers for personalized integration into care plans.\n",
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"description": "IMATIFLOW 400, containing Imatinib IP 400mg, represents a breakthrough in targeted cancer therapy, offering patients a precise weapon against specific malignancies. This oral medication belongs to the class of tyrosine kinase inhibitors, revolutionizing treatment for conditions once deemed challenging to manage. By blocking abnormal proteins that fuel cancer cell growth, IMATIFLOW 400 helps restore normal cellular function and improves quality of life for many users.\n\nProduct Overview\nIMATIFLOW 400 is a branded formulation of Imatinib mesylate 400mg, produced to high pharmaceutical standards for consistent efficacy and bioavailability. Each tablet delivers the active ingredient in a film-coated form, designed for once-daily administration with food to enhance absorption and minimize gastrointestinal upset. Developed for adult patients, it targets cancers driven by dysregulated tyrosine kinases like BCR-ABL, c-KIT, and PDGFR, making it a cornerstone in modern oncology protocols.\n\nThe medication's mechanism hinges on competitive inhibition at the ATP-binding site of these kinases, halting downstream signaling pathways that promote uncontrolled proliferation, survival, and metastasis of malignant cells. Unlike traditional chemotherapy, which broadly attacks dividing cells, IMATIFLOW 400 spares most healthy tissues, leading to a more favorable safety profile. Clinical data from pivotal trials underscore its role as first-line therapy, with high response rates observed within months of initiation.\n\nPrimary Uses\nIMATIFLOW 400 excels in treating chronic myeloid leukemia (CML), particularly in the chronic phase where it induces deep molecular responses in over 80% of patients. It suppresses the Philadelphia chromosome-positive cells hallmark of CML by inhibiting the BCR-ABL fusion protein, dramatically extending progression-free survival. For newly diagnosed patients, standard dosing starts at 400mg daily, often achieving complete cytogenetic remission.\n\nIn gastrointestinal stromal tumors (GIST), IMATIFLOW 400 targets KIT or PDGFRA mutations, shrinking unresectable tumors and delaying progression in advanced cases. The recommended dose remains 400mg once daily, with potential escalation to 600-800mg for resistant strains, as per oncology guidelines. It also finds application in dermatofibrosarcoma protuberans (DFSP), aggressive systemic mastocytosis, and certain myelodysplastic syndromes, broadening its utility in precision medicine.\n\nHealthcare providers monitor response via PCR for BCR-ABL transcripts in CML or imaging for GIST, adjusting therapy based on milestones like major molecular response. Patients with Ph+ acute lymphoblastic leukemia (ALL) may receive it adjunctively, enhancing outcomes when combined with chemotherapy. Overall, IMATIFLOW 400 transforms these diseases from fatal to chronically manageable.\n\nKey Benefits\nOne standout benefit of IMATIFLOW 400 is its oral convenience, eliminating the need for frequent hospital visits associated with infusions. Response rates exceed 90% in early CML, with many patients achieving treatment-free remission after sustained deep responses, a paradigm shift from interferon-era therapies.\n\nTumor control in GIST prevents life-threatening complications like bowel obstruction, improving survival from months to years. Its specificity reduces severe toxicities, allowing patients to maintain daily activities, work, and social engagements with minimal disruption. Long-term studies report 10-year survival rates above 80% in CML, underscoring durable efficacy.\n\nAdditional advantages include cost-effectiveness over biologics and compatibility with supportive care like hydroxyurea for cytoreduction. Fluid retention, while common, responds well to diuretics, preserving cardiac function. For Indian patients, accessible pricing via brands like IMATIFLOW 400 supports equitable care in resource-limited settings.\n\nPotential Side Effects\nWhile generally well-tolerated, IMATIFLOW 400 can cause edema (swelling in legs or face) in up to 70% of users, managed by dose reduction or supportive measures. Gastrointestinal issues like nausea, vomiting, and diarrhea affect 40-50%, often resolving with antiemetics and dietary adjustments.\n\nMusculoskeletal pain, cramps, and fatigue occur frequently, alongside rash and abdominal discomfort. Hematologic effects include neutropenia or thrombocytopenia, necessitating regular blood counts. Rare but serious risks involve liver enzyme elevation, heart failure, or hemorrhage; prompt reporting of symptoms like shortness of breath or yellowing skin is crucial.\n\nAvoid grapefruit juice, as it elevates drug levels, and inform doctors of concurrent medications like CYP3A4 inhibitors. Pregnancy category D status advises contraception, with monitoring for growth retardation in exposed fetuses. Dizziness may impair driving, so caution is essential during initial weeks.\n\nDosage and Administration Guidelines\nSwallow IMATIFLOW 400 whole with a meal and full glass of water to optimize pharmacokinetics and reduce esophageal irritation. The standard adult dose for CML chronic phase is 400mg daily; for accelerated phase or blast crisis, 600mg. GIST dosing mirrors 400mg, titrated based on tolerance and response.\n\nRenal or hepatic impairment requires dose adjustments—reduce to 300-400mg in moderate cases. Do not crush or chew tablets. Missed doses should be taken promptly unless near the next, avoiding doubles. Long-term use demands quarterly monitoring of CBC, liver function, and ECG.\n\nPrecautions and Interactions\nPatients with a cardiac history need baseline echocardiograms, as QT prolongation or effusion risks exist. Drug interactions abound: St. John's wort induces metabolism, reducing efficacy; ketoconazole boosts levels. Vaccines, especially live ones, are contraindicated during therapy.\n\nRegular dermatologic checks mitigate skin cancer risk from prolonged use. Hydration combats fluid retention, and low-salt diets aid management. Steris Healthcare emphasizes patient education via counseling on adherence for optimal outcomes.\n\nConclusion\nIMATIFLOW 400 (Imatinib IP 400mg) stands as a testament to targeted therapy's power, offering robust control over CML, GIST, and related cancers with a balance of efficacy and manageability. Its benefits in prolonging life and enhancing daily functioning far outweigh transient side effects for most when monitored diligently. Consult oncologists for personalized plans, ensuring this innovative treatment maximizes hope and health in the fight against cancer.",
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"description": "METAPECT MF KID SUSPENSION stands out as a specialized formulation from Steris Healthcare Pvt Ltd, blending Mefenamic Acid, a non-steroidal anti-inflammatory drug (NSAID), with Paracetamol, a widely used analgesic and antipyretic. Typically available in a 60ml bottle with child-friendly flavoring, it contains precise concentrations like 100mg Mefenamic Acid and 250mg Paracetamol per 5ml serving, ensuring accurate dosing via the included measuring cup. This sugar-free or low-sugar variant minimizes dental risks while providing rapid absorption for faster onset compared to solid forms. Manufactured under stringent quality controls, it supports pediatric care by addressing inflammation at its source through COX enzyme inhibition, which curbs prostaglandin production responsible for pain signals and fever response.\n\nThe suspension's dual-action mechanism sets it apart: Paracetamol targets the brain's hypothalamus to regulate body temperature and elevate pain thresholds, while Mefenamic Acid reduces tissue swelling and inflammatory mediators. This synergy makes METAPECT MF KID SUSPENSION more effective than single-ingredient options for multifaceted symptoms. Healthcare professionals often recommend it for short-term use in infants over six months and children, always under medical guidance to match age and weight-based dosages.\n\nKey Uses\nMETAPECT MF KID SUSPENSION excels in managing fever associated with viral infections, teething, or post-vaccination reactions. It swiftly lowers elevated temperatures, promoting comfort and better sleep for restless kids.\n\nFor pain relief, it tackles mild to moderate discomfort from headaches, toothaches, earaches, and sore throats common during colds or flu. Caregivers report noticeable easing of symptoms within 30-60 minutes, allowing children to resume play or eat without distress.\n\nAdditionally, it soothes body aches, muscle strains from minor injuries, or joint pains in growing kids. In cases of post-surgical recovery or inflammatory episodes, it provides reliable support without the need for stronger opioids.\n\nMajor Benefits\nThe primary benefit lies in its comprehensive symptom control, combining antipyretic, analgesic, and anti-inflammatory effects for holistic relief. Children experience reduced fever, less pain, and diminished swelling, leading to improved appetite and activity levels.\n\nIts liquid suspension format ensures easy administration—no choking risks—and precise dosing prevents under- or overdosing. Flavored options like mango enhance compliance, turning medicine time into a less daunting routine for picky eaters.\n\nCompared to alternatives, METAPECT MF KID SUSPENSION offers quicker bioavailability due to its oral liquid state, ideal for emergencies like high fever spikes at night. Long-term, it supports faster recovery by minimizing inflammation, potentially shortening illness duration when used as directed.\n\nBenefit\tDescription:\tAdvantage over Single Agents\nFever Reduction\tLowers temperature via hypothalamic action \tFaster than Paracetamol alone\nPain Relief\tBlocks pain signals and prostaglandins. \tSuperior for inflammatory pain\nAnti-Inflammatory\tReduces swelling in tissues \tAddresses root cause, not just symptoms\nEasy Dosing\tLiquid with dropper for accuracy \tChild-friendly, no splitting tablets\nPotential Side Effects\nWhile generally well-tolerated, METAPECT MF KID SUSPENSION may cause mild gastrointestinal issues like nausea, vomiting, stomach pain, or indigestion in some children, especially if taken on an empty stomach. Administering with food can mitigate this.\n\nLess common effects include drowsiness, dizziness, or allergic reactions such as rashes, itching, or swelling—seek immediate medical help if these occur. Prolonged use risks liver strain from Paracetamol or kidney concerns from Mefenamic Acid, so adhere strictly to prescribed durations.\nRarely, it might lead to diarrhea, headache, or elevated liver enzymes. Monitoring is key; consult a doctor for persistent symptoms or in kids with pre-existing conditions like asthma or ulcers.\n\nDosage Guidelines\nFollow pediatrician-recommended doses based on weight: typically 5-10ml every 6-8 hours, not exceeding 4 doses daily. Shake well before use and store below 30°C away from light.\nAvoid in neonates under 6 months or those with hypersensitivity. Hydration and diet play roles in efficacy—pair with plenty of fluids.\nConclusion\nMETAPECT MF KID SUSPENSION empowers parents with a dependable tool for childhood pain and fever, blending efficacy, safety, and convenience under Steris Healthcare's trusted banner. Quick relief restores normalcy, but professional oversight ensures optimal outcomes.",
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