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"description": "Description: \nSACUSMART 200 is a combination medicine containing Sacubitril (97 mg) and Valsartan (103 mg), specifically designed to manage chronic heart failure with reduced ejection fraction (HFrEF). This dual-acting therapy is classified as an angiotensin receptor neprilysin inhibitor (ARNI) and is widely prescribed to reduce the risk of cardiovascular death and hospitalization in patients with heart failure.\n\nHeart failure is a progressive condition where the heart cannot pump blood efficiently to meet the body’s needs. SACUSMART 200 improves the efficiency of the heart by relaxing blood vessels, reducing fluid retention, and lowering strain on the heart, helping patients live a better and longer life.\n\n \nWhat is SACUSMART 200?\n \n\nSACUSMART 200 is a highly effective heart failure medication that combines two active components:\n\nSacubitril (97 mg) – a neprilysin inhibitor that increases levels of natriuretic peptides, leading to vasodilation, sodium excretion, and reduced stress on the heart.\n\nValsartan (103 mg) – an angiotensin II receptor blocker (ARB) that relaxes blood vessels, lowers blood pressure, and prevents harmful effects of angiotensin II.\n\nTogether, these mechanisms make SACUSMART 200 a superior alternative to traditional ACE inhibitors or ARBs alone in treating chronic heart failure.\n\n \nUses of SACUSMART 200\n \n\nSACUSMART 200 is prescribed for:\n\nChronic heart failure with reduced ejection fraction (HFrEF)\n\nReducing risk of hospitalization due to worsening heart failure\n\nImproving survival rates in patients with heart failure\n\nEnhancing exercise tolerance and quality of life in long-term heart failure management\n\n \nBenefits of SACUSMART 200\n \n\nDual action with neprilysin inhibition + ARB effect for comprehensive heart protection\n\nProven to reduce mortality and hospitalization risk in heart failure patients\n\nImproves symptoms such as breathlessness, fatigue, and swelling\n\nHelps patients regain better physical stamina and daily activity levels\n\nLong-term use significantly contributes to improved quality of life\n\n \nPossible Side Effects of SACUSMART 200\n \n\nWhile SACUSMART 200 is effective and generally well tolerated, some patients may experience:\n\nLow blood pressure (hypotension)\n\nIncreased blood potassium levels (hyperkalemia)\n\nDizziness or light-headedness\n\nKidney function changes\n\nCough\n\nRarely, serious allergic reactions or angioedema (swelling of face, lips, or throat)\n\nImmediate medical attention is required if severe swelling, difficulty breathing, or fainting occurs.\n\n \nPrecautions Before Using SACUSMART 200\n \n\nDo not use if you are allergic to sacubitril, valsartan, or other ARBs\n\nAvoid if you have taken an ACE inhibitor within the last 36 hours due to the risk of angioedema\n\nNot recommended for patients with a history of hereditary angioedema\n\nCaution in patients with severe kidney or liver disease\n\nPregnant and breastfeeding women should avoid this medicine due to harmful effects on the baby\n\nAlways monitor blood pressure, kidney function, and potassium levels while on this treatment\n\n \nDrug Interactions\n \n\nSACUSMART 200 may interact with:\n\nACE inhibitors – should not be combined, risk of angioedema\n\nPotassium supplements or potassium-sparing diuretics – risk of high potassium\n\nNSAIDs (e.g., ibuprofen, naproxen) – may reduce kidney function\n\nLithium – risk of lithium toxicity\n\nDiuretics – may increase the risk of low blood pressure\n\nAlways inform your doctor about all medicines, supplements, or herbal products you are taking before starting SACUSMART 200.\n\n \nConclusion\n \n\nSACUSMART 200 (Sacubitril 97 mg & Valsartan 103 mg) is a breakthrough treatment in managing chronic heart failure with reduced ejection fraction (HFrEF). By combining neprilysin inhibition and angiotensin receptor blockade, it not only reduces symptoms but also significantly lowers the risk of hospitalization and death, improving both longevity and quality of life.\n\nFor patients living with heart failure, SACUSMART 200 offers a scientifically proven and clinically superior solution to regain control over their health and live a more fulfilling life.",
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"description": "SACUSMART 25 is a potent medication used in the treatment of chronic heart failure. It combines two essential active ingredients, Sacubitril (12 mg) and Valsartan (13 mg), working synergistically to improve heart function and reduce the risk of hospitalization due to heart failure. This combination medication belongs to the class of drugs known as ARNI (Angiotensin Receptor-Neprilysin Inhibitors) and is widely prescribed to manage heart failure symptoms, enhance quality of life, and prolong survival in patients with reduced ejection fraction.\n\n \n\nKey Benefits:\n \n\nImproves Heart Function: SACUSMART 25 enhances the ability of the heart to pump blood more efficiently, reducing symptoms of heart failure such as breathlessness and fatigue.\n\nReduces Hospitalization Risk: By improving heart function and preventing fluid buildup, SACUSMART 25 significantly reduces the likelihood of heart failure-related hospitalizations.\n\nLowers Blood Pressure: The combination of Sacubitril and Valsartan effectively lowers blood pressure, which helps reduce the strain on the heart and prevent further complications.\n\nEnhances Quality of Life: By managing the symptoms of heart failure, SACUSMART 25 helps patients lead a more active and comfortable life.\n\nLong-term Survival: Studies show that the combination therapy of Sacubitril and Valsartan can improve survival rates in patients with chronic heart failure compared to traditional therapies.\n\n \n\nHow Does It Work?\n \n\nSACUSMART 25 works by targeting two critical pathways in the regulation of blood pressure and heart function:\n\nSacubitril’s Role: As a neprilysin inhibitor, Sacubitril prevents the breakdown of natriuretic peptides, which are proteins that promote blood vessel dilation, sodium excretion, and reduced blood pressure. This leads to a decreased workload on the heart, allowing it to function more efficiently and with less strain.\n\nValsartan’s Role: Valsartan, as an angiotensin II receptor blocker, inhibits the action of angiotensin II, a hormone responsible for vasoconstriction (narrowing of blood vessels). By blocking this effect, Valsartan helps blood vessels remain relaxed, improving blood flow and reducing blood pressure.\n\nTogether, these mechanisms improve cardiac function, reduce blood pressure, and enhance the overall cardiovascular health of patients with heart failure.\n\n \n\nDirections for Use:\n \nDosage: SACUSMART 25 should be taken exactly as prescribed by a healthcare provider, typically once or twice daily, depending on the severity of the heart condition.\n\nAdministration: The tablet should be swallowed whole with water, with or without food. It's important not to crush or chew the tablet as this could affect the release and absorption of the medication.\n\nMissed Dose: If a dose is missed, take it as soon as possible unless it is almost time for the next scheduled dose. Do not double the dose to make up for a missed one.\n\nRegular Monitoring: Patients should regularly monitor their blood pressure and kidney function, as SACUSMART 25 can lower blood pressure significantly and may affect kidney health.\n\n \n\nSide Effects:\n \n\nWhile SACUSMART 25 is generally well-tolerated, some individuals may experience side effects. It’s important to be aware of these potential reactions and consult a doctor if they occur.\n\nCommon Side Effects:\nLow blood pressure (hypotension)\nDizziness or lightheadedness\nElevated potassium levels (hyperkalemia)\nCough\nFatigue\n",
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"description": "SACUBRIGHT 200 \nSacubitril (97mg), Valsartan (103mg)\nSACUBRIGHT 200 is a combination medication containing two active ingredients: Sacubitril (97mg) and Valsartan (103mg). This combination is designed to provide dual inhibition of the renin-angiotensin-aldosterone system (RAAS) for the treatment of heart failure with reduced ejection fraction (HFrEF).\n\nSacubitril is a neprilysin inhibitor, while Valsartan is an angiotensin II receptor blocker (ARB). Together, they work synergistically to improve cardiovascular outcomes in patients with HFrEF by targeting different pathways involved in the pathophysiology of heart failure.\n\nNeprilysin is an enzyme responsible for the degradation of natriuretic peptides, which play a crucial role in regulating blood pressure and fluid balance. By inhibiting neprilysin, Sacubitril increases the levels of natriuretic peptides, leading to vasodilation, natriuresis, and diuresis, which helps reduce blood pressure, preload, and afterload on the heart.\n\nValsartan, as an ARB, blocks the effects of angiotensin II, a vasoconstrictor and stimulator of aldosterone secretion. By antagonizing the angiotensin II type 1 (AT1) receptors, Valsartan dilates blood vessels, reduces blood pressure, and attenuates the deleterious effects of angiotensin II on cardiac remodeling and fibrosis.\n\nSACUBRIGHT 200 is indicated for the treatment of symptomatic HFrEF in patients with New York Heart Association (NYHA) class II-IV heart failure. Clinical studies have demonstrated that this combination therapy reduces the risk of cardiovascular death and hospitalization for heart failure compared to traditional therapy with angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) alone.\n\nAs with any medication, SACUBRIGHT 200 may cause side effects, including hypotension, hyperkalemia, renal impairment, and angioedema. Patients should be monitored regularly for these adverse effects, especially during initiation and dose titration.\n\nOverall, SACUBRIGHT 200 represents an innovative approach to the management of HFrEF, offering superior efficacy and cardiovascular benefits compared to standard therapy. However, it should only be used under the supervision of a healthcare professional experienced in the management of heart failure and in accordance with established treatment guidelines.\n\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order Now\nhttps://www.sterisonline.com/product/sacubright-200-134307\n\n\n\n",
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