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{ "products": [ { "_id": "6abe4471401ae1a1106d67d9", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Bisoprolol 1.25mg", "description": "Bisoprolol 1.25mg is the smallest tablet strength of bisoprolol, a heart-selective beta-1 blocker. Doctors usually prescribe it to start treatment or to build up the dose gradually in people with high blood pressure, chronic stable heart failure, or fast heart rhythms. It suits older adults, people with mild heart failure, and anyone who reacts strongly to beta-blockers. The medicine slows the heartbeat and eases the force of each contraction, so the heart works less hard. BISOGARD 1.25 from Steris Healthcare Pvt. Ltd. comes in a strip pack of 15 tablets. It is a Schedule H medicine, so it must only be started, changed, or stopped on a doctor's advice.\n\nProduct Snapshot\n\nBrand: BISOGARD 1.25\nManufacturer/Marketer: Steris Healthcare Pvt. Ltd., a WHO-GMP and ISO-certified pharmaceutical company in India\nActive ingredient: Bisoprolol Fumarate 1.25mg\nForm: Tablet\nPack size: 15 tablets\nDrug class: Cardioselective beta-1 blocker\nLegal status: Schedule H (valid prescription required)\nAvailability: Through Steris Healthcare's authorized pharmacies and its B2B PCD franchise network across India\nWhat Is Bisoprolol 1.25mg?\n\nIf your doctor has just prescribed bisoprolol 1.25mg, you have been given the lowest dose on purpose. Bisoprolol is a cardioselective beta-1 blocker, meaning it acts mostly on receptors in the heart and has much less effect on the lungs and blood vessels. This is a major reason it is preferred over older, non-selective beta-blockers, especially for people who also have a mild breathing problem.\n\nThe 1.25mg tablet is not a “light” medicine for mild illness. It is a carefully chosen entry point. In heart failure, a weakened heart can struggle if its rate or pressure drops too quickly, so cardiologists follow a “start low, go slow” approach. Treatment begins at 1.25mg, the response is watched for one to two weeks, and the dose is raised step by step (commonly 2.5mg, 3.75mg, 5mg, 7.5mg, and up to 10mg) as the heart adapts. That is why BISOGARD 1.25 is often the first tablet a newly diagnosed heart failure patient takes.\n\nWhat Is Bisoprolol 1.25mg Used For?\n\nDoctors commonly prescribe this strength for:\n\nChronic heart failure (HFrEF): as the first step of dose titration in patients with a reduced ejection fraction, alongside ACE inhibitors/ARBs and diuretics\nHigh blood pressure: especially in older adults, people with low body weight, and those who are sensitive to blood-pressure-lowering drugs\nStable angina: to reduce the heart's oxygen demand and relieve chest discomfort\nAfter a heart attack: in selected patients, under a cardiologist's care\nHeart rate control in some arrhythmias: sometimes used off-label at a low dose to gently bring down a fast heart rate\n\nAt 1.25mg, bisoprolol is seldom meant as the long-term sole treatment for high blood pressure in an otherwise healthy adult. It is usually the first rung of a titration ladder, or a steady maintenance dose for patients who are unusually beta-blocker sensitive (older age, low body weight, or borderline low pressure or pulse).\n\nHow Does Bisoprolol Work?\n\nBisoprolol selectively blocks beta-1 adrenergic receptors, which are packed mainly into heart muscle. This leads to several effects:\n\nSlower heart rate: the heart has more time to fill and rest between beats\nGentler contractions: the heart muscle needs less oxygen and energy\nLess renin from the kidneys: this helps blood pressure fall gradually over time\nLower overall cardiac workload: a real advantage for a heart that already struggles to pump well, as in heart failure\nKey Benefits of BISOGARD 1.25\nA gentle starting dose, well suited to careful titration in frail or elderly patients\nHeart-focused action, with less effect on the lungs and peripheral blood vessels than non-selective beta-blockers\nOnce-daily dosing, which makes it easier to stay on treatment\nA guideline-recommended beta-blocker for HFrEF with well-established outcomes data [Reviewer note: insert specific outcome statistics/trial citation pending medical sign-off]\nMade by Steris Healthcare Pvt. Ltd. under WHO-GMP and ISO-certified standards\nDosage Guidance\nUsual starting dose (heart failure): 1.25mg once a day, preferably in the morning\nDose increases: typically every 1–2 weeks (2.5mg, 3.75mg, 5mg, 7.5mg, up to a maximum of 10mg daily), depending on how well you tolerate it and on your pulse and blood pressure\nHigh blood pressure (sensitive patients): 1.25mg to 5mg once daily, as set by your doctor\nHow to take it: at the same time every day, with or without food, swallowed whole with water\nIf you miss a dose: take it when you remember, unless the next dose is almost due. Never take a double dose.\nNever stop suddenly: abrupt withdrawal can cause a rebound rise in heart rate, blood pressure, or chest pain. The dose must be reduced gradually under medical supervision.\nIs It Better to Take Bisoprolol in the Morning or at Night?\n\nMost doctors advise a morning dose. Bisoprolol lowers pulse and blood pressure, and taking it early matches its action to your daytime activity. A night-time dose could add to the body's natural overnight dip in blood pressure and raise the chance of dizziness when getting up in the dark. Some people who feel tired during the day are told by their doctor to switch to the evening. Do not change your dosing time without your doctor's approval.\n\nSide Effects of Bisoprolol 1.25mg\n\nCommon side effects\n\nTiredness or fatigue\nDizziness or light-headedness, especially on standing quickly\nCold hands or feet\nSlow pulse (bradycardia)\nHeadache\nMild stomach upset (nausea, loose stools)\nDisturbed sleep\n\nSerious side effects (get medical help promptly)\n\nVery slow heartbeat or fainting\nIncreasing breathlessness or swollen legs/ankles, which may mean heart failure is worsening\nAllergic reaction: rash, swelling of the face or throat, trouble breathing\nCold, numb, or bluish fingers and toes\nWheezing or new breathing difficulty, particularly in people with asthma or COPD\nMood changes, low mood, or confusion\nWhat Are the Bad Side Effects of Bisoprolol?\n\nThe effects that need urgent attention are a dangerously slow pulse, fainting, signs of worsening heart failure (swelling, breathlessness), severe allergic reactions, and airway tightening in people with lung disease. These are uncommon at the 1.25mg dose, but anyone who notices them should seek medical help right away. [Reviewer note: specific incidence rates pending clinical/medical sign-off]\n\nSubstitutes & Comparable Beta-Blockers\nMolecule\tSelectivity\tTypical Use Case\nBisoprolol\tHighly cardioselective\tHeart failure titration, hypertension\nMetoprolol Succinate ER\tCardioselective\tHypertension, angina, heart failure\nAtenolol\tCardioselective (older agent)\tHypertension\nCarvedilol\tNon-selective with alpha-blocking action\tHeart failure (adds vasodilation)\nPropranolol\tNon-selective\tMigraine prevention, anxiety-related fast heartbeat, essential tremor\nPrecautions & Who Should Avoid Bisoprolol\nNot suitable for people with severe bradycardia, certain forms of heart block (unless a pacemaker is fitted), unstable or acutely decompensated heart failure, or severe uncontrolled asthma\nUse carefully in diabetes, because beta-blockers can hide the warning signs of low blood sugar\nTake care in peripheral vascular disease, as cold extremities or leg pain on walking may worsen\nNever stop it abruptly; always taper under a doctor's guidance\nTell your doctor about every medicine you use, especially other blood-pressure drugs, calcium channel blockers, and certain antiarrhythmics\nIn pregnancy and breastfeeding, use only if your doctor advises it after weighing benefits and risks\nIs Bisoprolol Safe for Kidneys?\n\nThe body clears bisoprolol through both the liver and the kidneys in roughly equal measure. It is generally considered safe for people with normal or mildly reduced kidney function. When kidney impairment is significant, drug levels in the blood can rise, so your doctor may lower the dose or monitor you more closely. Always tell your prescriber about any kidney disease before starting.\n\nIs Bisoprolol a High-Risk Medication?\n\nBisoprolol is not a narrow therapeutic index drug like tacrolimus or warfarin, where small dose differences matter greatly. Even so, it needs supervised use because it directly affects heart rate and blood pressure. The main dangers are stopping it suddenly, which can set off rebound cardiac events, and using it with certain existing rhythm disorders. Taken as prescribed and checked regularly, it has a long and reassuring safety record.\n\nDoes 1.25mg Bisoprolol Lower Blood Pressure?\n\nYes. Even the smallest dose measurably reduces heart rate and blood pressure by lightening the heart's workload and reducing renin-driven narrowing of blood vessels. At this strength the effect on blood pressure is fairly mild, which is exactly why it is a safe place to begin, especially for older adults or people starting heart failure treatment. The dose is then raised gradually to reach full benefit.\n\nFrequently Asked Questions\n\n1. What is 1.25 mg of bisoprolol used for?\nMainly as a low starting dose when building up treatment for chronic heart failure, and for high blood pressure in people who are very sensitive to beta-blockers, such as older adults.\n\n2. What are the bad side effects of bisoprolol?\nThe more serious ones are a very slow pulse, fainting, worsening heart failure signs (swelling, breathlessness), severe allergy, and breathing trouble in people with lung conditions.\n\n3. What are the common side effects of bisoprolol fumarate 1.25 mg tablets?\nTiredness, dizziness, cold hands and feet, mild headache, and a slightly slower pulse.\n\n4. Is it better to take bisoprolol in the morning or at night?\nMorning is usually preferred so its effect fits daytime activity, though your doctor may suggest evenings in some cases.\n\n5. What is the cost of bisoprolol?\nPrice depends on strength, pack size, and brand. Use the “Check Price” option above for current BISOGARD 1.25 pricing from Steris Healthcare.\n\n6. Does 1.25 mg bisoprolol lower blood pressure?\nYes, though only modestly at this dose. The dose is often stepped up over time.\n\n7. Is bisoprolol safe for kidneys?\nGenerally yes for normal or mildly reduced kidney function. People with significant kidney impairment need dose adjustment and monitoring.\n\n8. Is bisoprolol a high-risk medication?\nIt is not a narrow therapeutic index drug, but it must never be stopped suddenly and should be used under medical supervision because of its direct effect on the heart.\n\n9. Can I take bisoprolol 1.25mg for the rest of my life?\nMany people with chronic heart failure or hypertension do take bisoprolol long term, but the dose usually rises as tolerated. Your doctor should review it regularly.\n\n10. What happens if I miss a dose of bisoprolol?\nTake it when you remember, unless the next dose is nearly due. In that case skip the missed one. Never take two together.\n\n11. Can bisoprolol 1.25mg cause weight gain?\nIt is not commonly reported at this dose. Fluid retention linked to heart failure itself should be reported to your doctor.\n\n12. Is bisoprolol safe for diabetic patients?\nIt can be used, with care, because beta-blockers may hide warning signs of low blood sugar such as a racing heartbeat.\n\n13. Can I stop taking bisoprolol suddenly if I feel fine?\nNo. Stopping abruptly can cause a rebound rise in heart rate, blood pressure, or chest pain. Reduce the dose gradually under medical guidance.\n\n14. Does bisoprolol interact with other blood pressure medicines?\nYes. Combining it with other drugs that lower heart rate or pressure (such as calcium channel blockers) can cause a very low pulse or pressure. Tell your doctor about all your medicines.\n\n15. Is BISOGARD 1.25 available without a prescription?\nNo. Bisoprolol is a Schedule H medicine in India and needs a valid prescription.\n\n16. How long does it take for bisoprolol 1.25mg to start working?\nSome effect on heart rate appears within hours, but the full benefit for blood pressure or heart failure symptoms builds over several weeks of regular use.\n\n17. Can pregnant women take bisoprolol?\nOnly if clearly necessary and prescribed by a doctor, as it may affect the baby's heart rate and growth.", "price": 39.0, "discountamount": 12.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2501, "imageuri": "https://productimages.withfloats.com/actual/6abe4474c205678e0b16a23a.png", "tileimageuri": "https://productimages.withfloats.com/tile/6abe4474c205678e0b16a23a.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-10-01T11:30:57.88Z", "updatedon": "2026-10-01T11:30:57.88Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/bisoprolol-1-25mg/2501", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Bisogard 1.25", "category": "CARDIOLOGYRANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "695b65af2800555f6696a6cf", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Cinacalcet 60 mg Tablet", "description": "CINASELECT 60: Comprehensive Guide to Cinacalcet 60 mg Tablets\nProduct Overview\nCINASELECT 60 is a pharmaceutical formulation containing Cinacalcet hydrochloride 60 mg as its active ingredient. This medication represents a significant advancement in the management of calcium metabolism disorders, particularly in patients with chronic kidney disease and parathyroid conditions. As a calcimimetic agent, CINASELECT 60 works by mimicking the action of calcium on tissues, helping to restore hormonal balance and mineral homeostasis in the body.\nThe 60 mg dosage strength offers an effective therapeutic option for patients requiring moderate to higher-level intervention in managing parathyroid hormone levels and associated calcium imbalances. CINASELECT 60 is manufactured under strict quality control standards, ensuring consistency, purity, and efficacy in every tablet.\nUnderstanding How CINASELECT 60 Works\nCINASELECT 60 operates through a sophisticated mechanism that targets the calcium-sensing receptors located on the surface of parathyroid gland cells. These receptors play a crucial role in regulating parathyroid hormone secretion, which in turn controls calcium and phosphorus levels in the bloodstream.\nWhen you take CINASELECT 60, the active ingredient cinacalcet binds to these calcium-sensing receptors, increasing their sensitivity to extracellular calcium. This enhanced sensitivity tricks the parathyroid glands into “thinking” there is more calcium present in the blood than there actually is. As a result, the glands reduce their production and release of parathyroid hormone (PTH).\nBy lowering PTH levels, CINASELECT 60 subsequently reduces calcium levels in the blood and decreases the amount of phosphorus absorbed from the intestines. This cascade effect helps restore the delicate mineral balance that is often disrupted in patients with kidney disease or parathyroid disorders.\nPrimary Therapeutic Uses\nSecondary Hyperparathyroidism in Chronic Kidney Disease\nThe primary indication for CINASELECT 60 is the treatment of secondary hyperparathyroidism in adult patients with chronic kidney disease (CKD) who are on dialysis. When kidneys fail to function properly, they cannot adequately regulate calcium and phosphorus levels, leading to excessive parathyroid hormone production. This condition can result in serious complications including bone disease, cardiovascular calcification, and increased mortality risk.\nCINASELECT 60 helps manage this condition by controlling PTH levels, thereby reducing the risk of bone complications such as osteitis fibrosa cystica and preventing the dangerous deposition of calcium in blood vessels and soft tissues.\nHypercalcemia in Parathyroid Carcinoma\nCINASELECT 60 is also indicated for treating hypercalcemia (elevated blood calcium levels) in patients with parathyroid carcinoma, a rare malignant tumor of the parathyroid glands. In these cases, the medication helps control the dangerously high calcium levels that can lead to kidney stones, bone pain, digestive issues, and neurological symptoms.\nPrimary Hyperparathyroidism\nFor patients with severe hypercalcemia due to primary hyperparathyroidism who cannot undergo parathyroidectomy or for whom surgery has failed, CINASELECT 60 offers a valuable medical management option. This provides relief for patients who are not surgical candidates due to advanced age, comorbidities, or other contraindications.\nKey Benefits of CINASELECT 60\nEffective PTH Control\nClinical studies have demonstrated that CINASELECT 60 significantly reduces parathyroid hormone levels in a dose-dependent manner. This reduction helps prevent the cascade of complications associated with elevated PTH, including bone mineral loss and cardiovascular calcification.\nImproved Calcium-Phosphorus Balance\nBy reducing PTH secretion, CINASELECT 60 helps normalize serum calcium and phosphorus levels. This is particularly important in dialysis patients, where mineral imbalances can lead to serious complications affecting bone health, cardiovascular function, and overall quality of life.\nReduced Cardiovascular Risk\nElevated calcium and phosphorus levels contribute to vascular calcification, a major risk factor for cardiovascular disease in patients with chronic kidney disease. By managing these mineral levels, CINASELECT 60 may help reduce the risk of cardiovascular complications, which are the leading cause of death in dialysis patients.\nBone Health Preservation\nUncontrolled secondary hyperparathyroidism leads to renal osteodystrophy, a condition characterized by abnormal bone metabolism. CINASELECT 60 helps protect bone integrity by normalizing PTH levels, potentially reducing fracture risk and preserving bone mineral density.\nAlternative to Surgery\nFor patients with primary hyperparathyroidism or parathyroid carcinoma who cannot undergo surgery, CINASELECT 60 provides an effective medical management option. This is particularly valuable for elderly patients or those with multiple comorbidities that make surgery risky.\nQuality of Life Improvement\nBy controlling symptoms associated with hypercalcemia and hyperparathyroidism, such as bone pain, muscle weakness, fatigue, and digestive issues, CINASELECT 60 can significantly improve patients' overall quality of life and functional capacity.\nConvenient Oral Administration\nCINASELECT 60 is administered orally, making it more convenient than injectable alternatives. This allows for outpatient management and reduces the burden on healthcare facilities and patients.\nPotential Side Effects and Adverse Reactions\nCommon Side Effects\nPatients taking CINASELECT 60 may experience several common side effects, which typically include nausea and vomiting, occurring in approximately 20-30% of patients. These gastrointestinal symptoms are usually mild to moderate and may improve over time as the body adjusts to the medication.\nDiarrhea is another frequent complaint, affecting roughly 20% of users. Some patients also report muscle pain or myalgia, dizziness, loss of appetite, and asthenia (general weakness or fatigue).\nSerious Side Effects Requiring Medical Attention\nHypocalcemia: The most significant risk associated with CINASELECT 60 is the development of low calcium levels in the blood. Severe hypocalcemia can lead to paresthesias (tingling sensations), muscle cramps or spasms, tetany, seizures, and QT interval prolongation on electrocardiogram, which can predispose to dangerous heart rhythm abnormalities.\nGastrointestinal Bleeding: There have been reports of gastrointestinal hemorrhage in patients taking cinacalcet, particularly in those with risk factors such as gastritis, ulcers, or concurrent use of other medications that increase bleeding risk.\nAdynamic Bone Disease: Oversuppression of PTH can lead to adynamic bone disease, a condition where bone turnover becomes abnormally low, potentially weakening bones despite normalized calcium levels.\nCardiovascular Effects: Some patients may experience worsening heart failure or arrhythmias, particularly if hypocalcemia develops. Close monitoring is essential in patients with underlying cardiovascular disease.\nAllergic Reactions: Though rare, hypersensitivity reactions including rash, urticaria, and angioedema have been reported.\nPrecautions and Contraindications\nCINASELECT 60 should not be used in patients with serum calcium levels below the normal range. It requires careful dose adjustment and monitoring in patients with hepatic impairment. The medication may interact with drugs metabolized by the CYP2D6 enzyme system and with medications that affect gastric pH.\nPregnant or breastfeeding women should use CINASELECT 60 only if clearly needed, as its safety in these populations has not been fully established. Regular monitoring of serum calcium, phosphorus, and PTH levels is essential throughout treatment.\nDosage and Administration Guidelines\nCINASELECT 60 should be taken orally with food or shortly after a meal, as this improves absorption and reduces gastrointestinal side effects. Tablets should be swallowed whole and not crushed, chewed, or divided.\nThe typical starting dose for secondary hyperparathyroidism is lower than 60 mg, with gradual titration based on PTH and calcium levels. The 60 mg strength is often used as part of the dose escalation process or as a maintenance dose once optimal PTH control is achieved.\nDose adjustments should be made no more frequently than every two to four weeks, as it takes this long to see the full effect of a dose change on PTH levels. Treatment should be individualized based on laboratory values and clinical response.\nMonitoring Requirements\nPatients on CINASELECT 60 require regular monitoring of serum calcium, phosphorus, and intact PTH levels. Calcium levels should be checked within one week of starting treatment or after any dose adjustment, and then monthly once stable. PTH levels should be measured one to four weeks after initiation or dose adjustment, then every one to three months during maintenance therapy.\nAdditionally, patients should be monitored for signs and symptoms of hypocalcemia, particularly during the initial treatment period. Electrocardiogram monitoring may be appropriate in patients at risk for QT prolongation.\nStorage and Handling\nCINASELECT 60 should be stored at room temperature, away from moisture and direct sunlight. The medication should be kept in its original container with the lid tightly closed to protect from humidity. Keep out of reach of children and pets. Do not use past the expiration date printed on the package.\nConclusion\nCINASELECT 60 (Cinacalcet 60 mg) represents a valuable therapeutic option in the management of secondary hyperparathyroidism associated with chronic kidney disease, hypercalcemia in parathyroid carcinoma, and primary hyperparathyroidism in patients who cannot undergo surgery. Its unique mechanism as a calcimimetic agent provides effective control of parathyroid hormone secretion, helping to restore mineral balance and prevent serious complications.\nThe benefits of CINASELECT 60 extend beyond simple laboratory value normalization. By controlling PTH, calcium, and phosphorus levels, this medication helps preserve bone health, reduce cardiovascular calcification risk, and improve overall quality of life for patients dealing with complex metabolic disorders. For patients who are not surgical candidates, CINASELECT 60 offers hope and effective symptom management.\nHowever, like all medications, CINASELECT 60 must be used judiciously under close medical supervision. The risk of hypocalcemia and other potential side effects necessitates regular laboratory monitoring and open communication between patients and healthcare providers. Patients should report any concerning symptoms promptly and attend all scheduled follow-up appointments.", "price": 740.0, "discountamount": 222.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2266, "imageuri": "https://productimages.withfloats.com/actual/695b65ebf30763183f64d4f7.png", "tileimageuri": "https://productimages.withfloats.com/tile/695b65ebf30763183f64d4f7.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-05T07:18:07.264Z", "updatedon": "2026-05-01T06:30:26.075Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//cinacalcet-60-mg-tablet/2266", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CINASELECT 60", "category": "NEPHROLOGYRANGE", "tags": [ "cinacalcet 60 mg", "cinacalcet mechanism of action.", "cinacalcet uses", "tab cinacalcet.", "cinacalcet dose.", "cinacalcet structure.", "cinacalcet tab.", "calcium and phosphorus levels in the bloodstream.", "parathyroid hormone secretion.", "calcium metabolism disorders.", "chronic kidney disease and parathyroid conditions.", "cinacalcet 60 mg", "cinacalcet 60", "Cinacalcet Tablets 60 mg price in India", "Buy Cinacalcet Tablets 60 mg online", "Cinacalcet 60 mg wholesale price", "Buy Cinacalcet Tablets 60 mg", "Get Cinacalcet Tablets 60 mg at best price" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "694e56c05837f90c86a7eb8c", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "empagliflozin linagliptin and metformin", "description": "LINALIGIP EMPAMET (Empagliflozin, Linagliptin, and Metformin Hydrochloride ER Tablets) stands out as a comprehensive triple therapy for adults with type 2 diabetes mellitus, combining three synergistic agents to tackle hyperglycemia from multiple angles. This once-daily extended-release formulation simplifies adherence while delivering robust glycemic control, weight management, and cardiovascular protection. Patients often seek it for its convenience in managing blood sugar levels when diet, exercise, and single agents fall short.\n​\n\nProduct Description and Composition\nLINALIGIP EMPAMET features Empagliflozin (typically 10-25mg), Linagliptin (5 mg), and Metformin Hydrochloride ER (up to 1000mg) in a single tablet, designed for prolonged release to minimize gastrointestinal upset. Empagliflozin, an SGLT2 inhibitor, blocks glucose reabsorption in the kidneys, promoting its excretion via urine. Linagliptin, a DPP-4 inhibitor, enhances incretin hormones like GLP-1 to boost insulin secretion and suppress glucagon. Metformin ER reduces hepatic glucose production and improves insulin sensitivity without hypoglycemia risk.\n​\n\nThis unique blend from Steris Healthcare ensures steady drug delivery over 24 hours, reducing peak-trough fluctuations for stable HbA1c reductions of 1.5-2.0%. The extended-release metformin coats the tablet core, dissolving gradually in the intestines for better tolerability compared to immediate-release forms. Ideal for Indian patients facing rising diabetes prevalence, it addresses insulin resistance, postprandial spikes, and caloric overload holistically.\n​\n\nMechanism of Action\nThe triple mechanism targets key diabetes pathways: Empagliflozin inhibits SGLT2 in proximal renal tubules, lowering blood glucose by 70-90g daily through glycosuria, independent of insulin. Linagliptin selectively binds DPP-4, prolonging GLP-1 and GIP activity to stimulate glucose-dependent insulin release from beta cells and curb glucagon-mediated gluconeogenesis. Metformin activates AMPK in hepatocytes, inhibiting gluconeogenesis while enhancing peripheral glucose uptake.\n​\n\nSynergy amplifies effects—SGLT2 inhibition provides insulin-independent control, DPP-4 boosts prandial responses, and metformin tackles fasting hyperglycemia—resulting in complementary HbA1c drops without overlapping toxicities. Clinical data show this combination yields superior efficacy over dual therapies, with added osmotic diuresis aiding fluid balance.\n​\n\nUses and Indications\nLINALIGIP EMPAMET treats type 2 diabetes in adults, as adjunct to diet and exercise, especially when metformin alone or dual therapy inadequately controls glycemia. Primary uses include newly diagnosed patients needing intensification, those with obesity (due to weight loss from glycosuria), and high-risk cardiovascular profiles benefiting from empagliflozin's heart protection. It excels in managing postprandial hyperglycemia, fasting glucose, and preventing complications like nephropathy.\n​\n\nPrescribed for patients intolerant to other agents or requiring simplified regimens, it suits Indian demographics with high metabolic syndrome rates. Not for type 1 diabetes or ketoacidosis; renal function (eGFR >45 mL/min) guides initiation.\n​\n\nKey Benefits\nLINALIGIP EMPAMET offers multifaceted advantages for long-term diabetes management:\n\nSuperior Glycemic Control: Achieves 1.8% HbA1c reduction in trials, outperforming monotherapies by targeting multiple defects.\n​\n\nWeight Loss: Empagliflozin induces 3-5kg loss via caloric excretion, countering metformin's neutral effect.\n​\n\nCardiovascular and Renal Protection: Reduces major adverse cardiac events (MACE) by 14% and slows CKD progression, per EMPA-REG outcomes.\n​\n\nLow Hypoglycemia Risk: Glucose-dependent actions of linagliptin and empagliflozin minimize lows, unlike sulfonylureas.\n​\n\nConvenience: Single-tablet ER dosing improves compliance, vital for busy lifestyles in Jaipur and beyond.\n​\n\nBlood Pressure Reduction: Mild diuretic effect lowers systolic BP by 3-5 mmHg.\n​\n\nThese benefits enhance quality of life, reducing fatigue, neuropathy risks, and healthcare costs.\n\nSide Effects\nCommon side effects mirror individual components but occur less due to synergy:\n\nGastrointestinal: Metformin ER causes less nausea/diarrhea (10-15%) than IR forms; titrate slowly.\n​\n\nGenitourinary: Empagliflozin raises UTI/genital mycotic infection risk (5-10%), managed with hygiene.\n​\n\nVolume Depletion: Orthostatic hypotension in 2-3%, especially with diuretics.\n​\n\nSerious effects include lactic acidosis (rare, <1/100,000 with metformin in eGFR >30), ketoacidosis (euglycemic, 0.1%), and acute kidney injury. Monitor for dehydration, pancreatitis signs, or bullous pemphigoid with linagliptin. Hypersensitivity rash or bone fractures warrant discontinuation.\n​\n\nSide Effect Category\tFrequency\tManagement\nNausea and Diarrhea\tCommon (10%)\tTake with food, slow titration \n​\nUTI/Mycotic Infections\tCommon (7%)\tHydration, antifungals \n​\nHypoglycemia\tRare (<2%)\tWith insulin, dose adjust \n​\nLactic Acidosis\tVery Rare.\tAvoid in renal/hepatic failure \n​\nKetoacidosis\tRare (0.1%)\tCheck ketones if nausea \n​\nDosage and Administration\nStart with Empagliflozin 10mg/Linagliptin 5mg/Metformin ER 1000mg once daily with morning meal to optimize absorption and reduce GI effects. Titrate metformin to 2000mg max based on tolerance; empagliflozin to 25mg if needed. Swallow whole; no crushing. Adjust for renal impairment (eGFR 30-45: max metformin 1000mg; <30 contraindicated). Elderly start low due to volume sensitivity.\n​\n\nMissed dose: Take soon if less than 12 hours late; skip otherwise. Discontinue pre-surgery or contrast use.\n\nPrecautions and Warnings\nAssess eGFR before and 3-6 months after initiation; hold if <45. Caution in dehydration, heart failure, or liver disease risks lactic acidosis. Educate on ketoacidosis symptoms (nausea, fatigue) despite normal glucose. Avoid excessive alcohol; monitor BP in hypertensives. Pregnancy category D—use insulin instead. Breastfeeding is contraindicated.\n​\n\nDrug interactions: Adding sulfonylureas/insulin heightens hypoglycemia; rifampin reduces linagliptin levels; ritonavir boosts empagliflozin exposure.\n\nFrequently Asked Questions\nWhat is LINALIGIP EMPAMET used for?\nControls type 2 diabetes via triple action on glucose excretion, incretins, and insulin sensitivity.\n​\nDoes it cause weight gain?\nNo—it promotes 2-4 kg loss, unlike some antidiabetics.\n​\n\nSafe for kidneys?\nRenal-protective; monitor eGFR.\n​\n\nHypoglycemia risk?\nMinimal without sulfonylureas.\n\nConclusion\nLINALIGIP EMPAMET revolutionizes type 2 diabetes care with its potent, convenient triple therapy, delivering glycemic mastery, weight benefits, and cardioprotection unmatched by singles or duos. Backed by landmark trials, it empowers patients toward complication-free lives when integrated with lifestyle changes. Consult physicians for personalized dosing to harness its full potential safely.", "price": 220.0, "discountamount": 66.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2257, "imageuri": "https://productimages.withfloats.com/actual/694e60c1db6d50f75e42e875.png", "tileimageuri": "https://productimages.withfloats.com/tile/694e60c1db6d50f75e42e875.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-26T09:34:56.604Z", "updatedon": "2026-03-13T10:59:31Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//empagliflozin-linagliptin-and-metformin/2257", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "LINALIGIP EMPAMET", "category": "DIABETIC RANGE", "tags": [ "empagliflozin 10 mg", "empagliflozin 25 mg", "empagliflozin 10 mg uses in hindi", "empagliflozin 10 mg tablet.", "type 2 diabetes mellitus.", "linagliptin", "Linagliptin 5 mg", "linagliptin 5 mg uses", "linagliptin tablet uses", "Linagliptin 5 mg price", "Empagliflozin, an SGLT2 inhibitor.", "Metformin ER reduces hepatic glucose production and improves insulin.", "LINALIGIP EMPAMET revolutionizes type 2 diabetes.", "empagliflozin linagliptin and metformin tablets", "empagliflozin linagliptin metformin combination tablet", "empagliflozin linagliptin metformin tablets uses", "empagliflozin linagliptin metformin triple combination", "empagliflozin linagliptin metformin dosage strength", "empagliflozin linagliptin metformin sustained release tablet", "empagliflozin linagliptin metformin medicine for diabetes", "empagliflozin linagliptin metformin tablet uses", "empagliflozin linagliptin metformin benefits", "empagliflozin linagliptin metformin for type 2 diabetes", "empagliflozin linagliptin metformin blood sugar control", "empagliflozin linagliptin metformin weight loss benefit", "what is empagliflozin linagliptin metformin tablet", "how does empagliflozin linagliptin metformin work", "empagliflozin linagliptin metformin tablet price in india", "empagliflozin linagliptin metformin tablet dosage", "empagliflozin linagliptin metformin before or after food" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "694d14f6274fc8b97e9b7120", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Mirtazapine 30mg", "description": "MIRTAZPRIME 30 is a pharmaceutical formulation containing Mirtazapine 30mg as per Indian Pharmacopoeia (IP) standards. This prescription medication belongs to a class of drugs known as tetracyclic antidepressants and represents an advanced therapeutic option for individuals struggling with major depressive disorder and related mental health conditions. Manufactured under stringent quality control measures, MIRTAZPRIME 30 offers patients a reliable and effective solution for managing depression while also addressing associated symptoms such as insomnia and anxiety.\nMirtazapine, the active pharmaceutical ingredient in MIRTAZPRIME 30, works through a unique dual mechanism that distinguishes it from other antidepressants. Unlike selective serotonin reuptake inhibitors (SSRIs), mirtazapine enhances the release of both norepinephrine and serotonin in the brain by blocking specific receptors. This innovative approach not only helps alleviate depressive symptoms but also provides sedative effects that can be particularly beneficial for patients experiencing sleep disturbances alongside depression.\nTherapeutic Uses and Applications\nMIRTAZPRIME 30 is primarily indicated for the treatment of major depressive disorder (MDD), a serious mental health condition characterized by persistent feelings of sadness, hopelessness, and loss of interest in daily activities. The medication has demonstrated significant efficacy in clinical trials, showing improvement in mood, energy levels, and overall quality of life for patients suffering from depression.\nBeyond its primary indication, healthcare providers may prescribe MIRTAZPRIME 30 for various off-label uses based on clinical judgment and patient needs. The medication has shown promise in managing generalized anxiety disorder, where excessive worry and tension interfere with daily functioning. Its sedative properties make it particularly valuable for patients experiencing insomnia related to depression or anxiety, as it can help restore healthy sleep patterns without the need for additional sleep medications.\nThe 30mg dosage strength represents a therapeutic level commonly prescribed for maintenance treatment after initial dose titration. Patients typically begin with lower doses and gradually increase to 30mg as their body adjusts to the medication and their symptoms require more robust management. This dosage provides an optimal balance between therapeutic efficacy and side effect management for many individuals.\nMIRTAZPRIME 30 may also be considered for patients who have not responded adequately to other antidepressant therapies, offering an alternative mechanism of action that can break through treatment-resistant depression. Additionally, its appetite-stimulating effects can be beneficial for patients experiencing significant weight loss due to depression or other medical conditions.\nKey Benefits and Therapeutic Advantages\nThe benefits of MIRTAZPRIME 30 extend beyond simple symptom relief, offering patients a multifaceted approach to mental health recovery. One of the most significant advantages is its relatively rapid onset of action compared to many other antidepressants. While most SSRIs require several weeks to demonstrate meaningful clinical improvement, patients taking mirtazapine often experience some relief from symptoms within one to two weeks, with continued improvement over subsequent weeks.\nThe dual neurotransmitter action of MIRTAZPRIME 30 provides comprehensive coverage of depressive symptoms. By enhancing both serotonergic and noradrenergic neurotransmission, the medication addresses the complex neurochemical imbalances underlying depression more thoroughly than single-mechanism antidepressants. This broader action can result in more complete symptom resolution and better overall outcomes.\nSleep improvement represents another crucial benefit of MIRTAZPRIME 30. The medication's sedative properties, particularly pronounced at lower doses, help patients fall asleep faster and enjoy more restorative sleep throughout the night. This is especially valuable since sleep disturbances are both a symptom and an exacerbating factor in depression. Better sleep quality contributes to improved daytime functioning, energy levels, and emotional regulation.\nUnlike many antidepressants that commonly cause sexual dysfunction, MIRTAZPRIME 30 has a relatively favorable profile in this regard. The medication is less likely to interfere with sexual function, making it an attractive option for patients who have experienced these troublesome side effects with other antidepressants. This characteristic can significantly improve treatment adherence and quality of life.\nThe appetite-stimulating effect, while considered a side effect by some, can be therapeutically beneficial for patients experiencing significant weight loss or poor appetite due to depression. MIRTAZPRIME 30 can help restore healthy eating patterns and reverse the physical decline that often accompanies severe depressive episodes.\nFurthermore, MIRTAZPRIME 30 does not typically cause the gastrointestinal side effects commonly associated with SSRI antidepressants, such as nausea, diarrhea, or stomach upset. This improved gastrointestinal tolerability enhances patient comfort and compliance with treatment regimens.\nPotential Side Effects and Safety Considerations\nWhile MIRTAZPRIME 30 offers numerous therapeutic benefits, patients should be aware of potential side effects that may occur during treatment. Understanding these effects helps patients make informed decisions and enables early identification of any concerning symptoms requiring medical attention.\nThe most commonly reported side effect is drowsiness or sedation, particularly during the initial weeks of treatment. This effect is typically most pronounced during the first few hours after taking the medication, which is why it's generally recommended for evening administration. Patients should exercise caution when driving, operating machinery, or engaging in activities requiring alertness until they understand how the medication affects them personally.\nIncreased appetite and weight gain represent another frequent side effect of MIRTAZPRIME 30. While beneficial for some patients, others may find this effect undesirable. Weight gain typically ranges from moderate to significant and appears to be dose-related. Patients concerned about weight should discuss dietary strategies and exercise plans with their healthcare provider.\nDry mouth is a common anticholinergic side effect that can cause discomfort but is generally manageable through increased fluid intake, sugar-free gum or candy, and good oral hygiene practices. Some patients may also experience dizziness, particularly when standing up quickly, due to the medication's effects on blood pressure regulation.\nConstipation may occur in some patients and can usually be managed through dietary modifications, increased fiber intake, adequate hydration, and regular physical activity. Less commonly, patients might experience confusion, abnormal dreams, or changes in thinking, particularly in older adults who may be more sensitive to the medication's effects.\nSerious side effects, while rare, require immediate medical attention. These include signs of allergic reactions such as rash, itching, swelling, severe dizziness, or difficulty breathing. Agranulocytosis, a dangerous decrease in white blood cells, is an extremely rare but serious complication that manifests as fever, sore throat, or signs of infection. Any unexplained fever or signs of infection should prompt immediate contact with a healthcare provider.\nSerotonin syndrome is another rare but potentially life-threatening condition that can occur when mirtazapine is combined with other medications affecting serotonin levels. Symptoms include agitation, hallucinations, rapid heartbeat, fever, excessive sweating, muscle stiffness, or coordination problems. Patients should inform their healthcare provider about all medications and supplements they are taking to avoid dangerous interactions.\nAbrupt discontinuation of MIRTAZPRIME 30 can lead to withdrawal symptoms, including nausea, anxiety, irritability, and flu-like symptoms. Therefore, any decision to stop the medication should be made in consultation with a healthcare provider who can develop an appropriate tapering schedule.\nImportant Usage Guidelines\nMIRTAZPRIME 30 should always be taken exactly as prescribed by a qualified healthcare professional. The medication is typically administered once daily, preferably in the evening before bedtime due to its sedative effects. Tablets should be swallowed whole with water and can be taken with or without food, though taking them with food may help reduce any stomach upset.\nConsistency in timing is important for maintaining stable blood levels of the medication and optimizing therapeutic effects. Patients should try to take their dose at approximately the same time each evening. If a dose is missed, it should be taken as soon as remembered unless it's close to the time for the next scheduled dose, in which case the missed dose should be skipped rather than doubling up.\nThe full therapeutic benefits of MIRTAZPRIME 30 may take several weeks to manifest. Patients should continue taking the medication as prescribed even if they don't feel immediate improvement. Premature discontinuation is a common reason for treatment failure in depression management.\nRegular follow-up appointments with the prescribing physician are essential for monitoring treatment response, adjusting dosages if necessary, and screening for potential side effects. Patients should maintain open communication with their healthcare team about their symptoms, concerns, and any changes in their condition.\nConclusion\nMIRTAZPRIME 30 represents a valuable therapeutic option in the comprehensive management of major depressive disorder and related conditions. Its unique mechanism of action, combining enhanced noradrenergic and serotonergic neurotransmission with sedative and appetite-stimulating properties, offers distinct advantages for carefully selected patients. The medication's ability to improve both mood symptoms and sleep disturbances makes it particularly useful for patients experiencing depression accompanied by insomnia.\nThe relatively favorable side effect profile, particularly regarding sexual function and gastrointestinal tolerability, enhances patient acceptance and adherence to treatment. While potential side effects such as sedation, increased appetite, and weight gain require monitoring and management, many patients find these effects tolerable compared to the debilitating symptoms of untreated depression.\nSuccess with MIRTAZPRIME 30, as with any antidepressant therapy, depends on proper patient selection, appropriate dosing, regular monitoring, and a comprehensive treatment approach that may include psychotherapy, lifestyle modifications, and social support alongside pharmacological intervention. Patients should work closely with their healthcare providers to optimize treatment outcomes and maintain long-term mental health wellness.\nThe decision to use MIRTAZPRIME 30 should always be made collaboratively between patient and physician, considering individual symptoms, treatment history, coexisting medical conditions, and personal preferences. With proper use under medical supervision, MIRTAZPRIME 30 can be an effective tool in helping patients reclaim their lives from the devastating effects of depression and move toward recovery and renewed well-being.", "price": 262.0, "discountamount": 79.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2254, "imageuri": "https://productimages.withfloats.com/actual/694d14f83d39ca31a28d046b.png", "tileimageuri": "https://productimages.withfloats.com/tile/694d14f83d39ca31a28d046b.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-25T10:41:58.966Z", "updatedon": "2026-03-13T07:46:51.004Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//mirtazapine-30mg/2254", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MIRTAZPRIME 30", "category": "NEUROLOGYRANGE", "tags": [ "MIRTAZPRIME 30", "Mirtazapine 30mg as per Indian Pharmacopoeia (IP) standards", "managing depression", "insomnia and anxiety.", "depression or anxiety.", "depredepressive episodes.", "helping patients reclaim their lives from the devastating effects of depression." ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "694cf85408591c1173b54c2f", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Pregabalin Epalrestat and Methylcobalamin Tablets", "description": "EPSTATE ED represents an advanced pharmaceutical formulation that combines three powerful therapeutic agents: Pregabalin, Epalrestat, and Methylcobalamin. This innovative triple-combination medication is specifically designed to address the complex pathophysiology of diabetic neuropathy and neuropathic pain conditions. By integrating multiple mechanisms of action, EPSTATE ED offers a comprehensive approach to managing nerve-related complications that significantly impact the quality of life for millions of individuals worldwide.\nThe formulation addresses not only the symptomatic relief of neuropathic pain but also targets the underlying metabolic derangements that contribute to nerve damage progression. This multi-pronged therapeutic strategy makes EPSTATE ED particularly valuable for patients who require more than symptomatic management alone.\nUnderstanding the Active Components\nPregabalin: The Neuropathic Pain Modulator\nPregabalin serves as the cornerstone analgesic component in EPSTATE ED. This anticonvulsant medication works by binding to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. Through this mechanism, Pregabalin reduces the release of excitatory neurotransmitters including glutamate, norepinephrine, and substance P. This reduction in neurotransmitter release effectively dampens the abnormal neural signaling that characterizes neuropathic pain conditions.\nThe molecule demonstrates excellent bioavailability and rapid absorption, allowing patients to experience relief within a relatively short timeframe. Its efficacy in managing various neuropathic pain syndromes has been extensively documented in clinical trials, establishing it as a first-line agent for diabetic peripheral neuropathy, postherpetic neuralgia, and other chronic neuropathic pain conditions.\nEpalrestat: The Aldose Reductase Inhibitor\nEpalrestat represents a unique addition to the formulation, functioning as a selective aldose reductase inhibitor. In diabetic conditions, excess glucose is converted to sorbitol through the polyol pathway, with aldose reductase serving as the rate-limiting enzyme. The accumulation of sorbitol within nerve cells leads to osmotic stress, depletion of myoinositol, and subsequent nerve dysfunction.\nBy inhibiting aldose reductase, Epalrestat prevents this harmful sorbitol accumulation, thereby addressing one of the fundamental metabolic abnormalities responsible for diabetic neuropathy. This disease-modifying approach distinguishes EPSTATE ED from purely symptomatic treatments. Epalrestat has been particularly well-studied in Asian populations and has demonstrated the ability to improve nerve conduction velocities and reduce subjective neuropathic symptoms over time.\nMethylcobalamin: The Neurotropic Vitamin\nMethylcobalamin, the bioactive form of Vitamin B12, completes the therapeutic triad in EPSTATE ED. Unlike cyanocobalamin, which requires conversion in the body, methylcobalamin is immediately available for utilization in crucial biochemical processes. It plays an indispensable role in myelin synthesis, the protective sheath surrounding nerve fibers that enables proper signal transmission.\nThis coenzyme participates in methionine synthesis and is essential for maintaining the structural and functional integrity of neurons. Methylcobalamin also facilitates nerve regeneration and has demonstrated neuroprotective properties in various experimental models. For patients with diabetic neuropathy, who often exhibit Vitamin B12 deficiency (sometimes exacerbated by metformin therapy), supplementation with methylcobalamin addresses both nutritional deficits and supports nerve health at a fundamental level.\nClinical Applications and Uses\nEPSTATE ED is primarily indicated for the comprehensive management of diabetic peripheral neuropathy, a condition affecting approximately 50% of individuals with long-standing diabetes. The symptoms of this condition range from tingling sensations and burning pain to numbness and loss of protective sensation, which can lead to serious complications including foot ulcers and amputations.\nBeyond diabetic neuropathy, EPSTATE ED may be prescribed for various neuropathic pain syndromes where the combination of pain relief, metabolic correction, and nerve support proves beneficial. Patients experiencing chronic nerve pain resulting from metabolic disturbances, nutritional deficiencies, or structural nerve damage may find this combination particularly effective.\nThe medication is typically recommended for adults who have not achieved adequate symptom control with single-agent therapy or who would benefit from the synergistic effects of the three components. Healthcare providers may prescribe EPSTATE ED when a patient requires both immediate symptom relief and long-term disease modification.\nKey Benefits and Therapeutic Advantages\nComprehensive Multi-Mechanism Action\nThe primary advantage of EPSTATE ED lies in its multi-faceted approach to neuropathic conditions. Rather than addressing only pain symptoms, the formulation simultaneously tackles pain perception, underlying metabolic abnormalities, and nutritional support for nerve health. This comprehensive strategy may lead to superior outcomes compared to monotherapy approaches.\nEnhanced Pain Relief\nClinical evidence supporting Pregabalin's efficacy in neuropathic pain is substantial. Patients often report significant reductions in pain intensity, improved sleep quality due to decreased nocturnal pain, and enhanced ability to perform daily activities. The pain-relieving effects typically manifest within the first week of therapy and continue to improve with ongoing treatment.\nDisease Modification Potential\nUnlike purely symptomatic treatments, the inclusion of Epalrestat provides genuine disease-modifying potential. By targeting the polyol pathway, EPSTATE ED may slow the progression of nerve damage in diabetic patients. Long-term use may preserve nerve function and prevent the worsening of neuropathic symptoms, offering hope beyond mere symptom management.\nImproved Nerve Conduction and Function\nThe combination of metabolic correction through Epalrestat and neurotropic support via Methylcobalamin creates an environment conducive to nerve regeneration and functional improvement. Studies have demonstrated improvements in nerve conduction velocity parameters with similar combination therapies, suggesting potential restoration of nerve function rather than simple symptom masking.\nConvenience of Combination Therapy\nFor patients who would otherwise require multiple separate medications, EPSTATE ED offers the convenience of a single tablet containing all three therapeutic agents. This simplification of medication regimens improves compliance, reduces pill burden, and may enhance overall treatment outcomes.\nQuality of Life Enhancement\nThe cumulative effect of pain reduction, improved nerve function, and better metabolic control translates into meaningful quality of life improvements. Patients report better mobility, reduced interference of pain with daily activities, improved mood, and enhanced social functioning.\nPotential Side Effects and Safety Considerations\nCommon Side Effects\nAs with any pharmaceutical agent, EPSTATE ED may produce certain adverse effects. The most commonly reported side effects are primarily attributable to the Pregabalin component and include dizziness, somnolence, peripheral edema, dry mouth, blurred vision, weight gain, and difficulty with concentration or attention. These effects are generally mild to moderate and often diminish with continued therapy as the body adapts to the medication.\nGastrointestinal symptoms such as constipation or nausea may occur, though they are typically manageable with dietary modifications or symptomatic treatment. Some patients experience increased appetite leading to weight gain, which requires monitoring, particularly in diabetic individuals where weight management is crucial.\nSerious but Rare Adverse Events\nThough uncommon, certain serious adverse effects warrant immediate medical attention. These include allergic reactions manifesting as rash, itching, swelling, severe dizziness, or breathing difficulties. Pregabalin has been associated with rare cases of angioedema, which requires prompt discontinuation and medical intervention.\nMental health changes, including mood alterations, anxiety, depression, agitation, or suicidal thoughts, have been reported with Pregabalin use, particularly in individuals with pre-existing psychiatric conditions. Patients and caregivers should remain vigilant for behavioral changes and report them immediately to healthcare providers.\nDrug Interactions and Precautions\nEPSTATE ED may interact with other central nervous system depressants, including alcohol, opioids, benzodiazepines, and antihistamines, potentially intensifying sedation and cognitive impairment. Patients should inform their healthcare provider of all medications, supplements, and substances they consume.\nIndividuals with kidney impairment require dose adjustments since Pregabalin is primarily eliminated through renal excretion. Regular monitoring of renal function may be necessary during long-term therapy.\nSpecial Population Considerations\nPregnant or breastfeeding women should use EPSTATE ED only when clearly necessary and under strict medical supervision, as the safety profile in these populations has not been fully established. Elderly patients may be more susceptible to side effects, particularly dizziness and confusion, necessitating careful dose titration and monitoring.\nPatients should be advised against abrupt discontinuation of EPSTATE ED, as sudden cessation of Pregabalin may precipitate withdrawal symptoms including insomnia, nausea, headache, anxiety, and sweating. Gradual dose reduction under medical supervision is recommended when discontinuing therapy.\nDosage and Administration Guidelines\nThe appropriate dosage of EPSTATE ED is highly individualized and should be determined by a qualified healthcare professional based on the patient's specific condition, response to therapy, and tolerance. Typically, treatment begins with a lower dose that is gradually increased to achieve optimal therapeutic benefit while minimizing adverse effects.\nPatients should take EPSTATE ED exactly as prescribed, with or without food, at consistent times each day to maintain stable blood levels. Missing doses should be addressed by taking the forgotten dose as soon as remembered, unless it's nearly time for the next scheduled dose. Double dosing to compensate for missed doses is not recommended.\nRegular follow-up appointments allow healthcare providers to assess treatment efficacy, monitor for adverse effects, and make necessary dose adjustments. Patients should maintain open communication with their medical team regarding symptom improvement, side effects, and any concerns that arise during therapy.\nPatient Counseling and Lifestyle Recommendations\nMaximizing the benefits of EPSTATE ED extends beyond simply taking the medication. Patients should be counseled on complementary lifestyle measures that support neuropathy management. Maintaining optimal glycemic control remains paramount for diabetic patients, as blood sugar management directly impacts neuropathy progression regardless of medication.\nRegular physical activity, within individual capabilities, promotes circulation, supports nerve health, and may enhance the therapeutic effects of EPSTATE ED. Daily foot examinations become critical for diabetic patients to identify potential injuries early, preventing serious complications.\nNutritional optimization, including adequate intake of B vitamins, antioxidants, and essential nutrients, supports the neurotropic effects of Methylcobalamin. Avoiding alcohol and tobacco, both of which can exacerbate neuropathy, is strongly recommended.\nPatients should be cautioned about activities requiring alertness, such as driving or operating machinery, especially during the initial treatment phase when dizziness and somnolence may be more pronounced. These effects typically improve with continued therapy, but individual responses vary.\nConclusion\nEPSTATE ED represents a thoughtfully designed pharmaceutical formulation that addresses the multifaceted nature of diabetic neuropathy and neuropathic pain through its unique combination of Pregabalin, Epalrestat, and Methylcobalamin. This triple-action approach offers patients more than symptomatic relief—it provides genuine disease modification potential, nutritional support, and comprehensive nerve health optimization.\nThe synergistic effects of these three components create a therapeutic profile that is greater than the sum of its parts. While Pregabalin efficiently manages pain symptoms and improves quality of life in the short term, Epalrestat works to address underlying metabolic derangements that drive disease progression, and Methylcobalamin provides essential neurotropic support for nerve regeneration and function.\nFor patients struggling with the debilitating effects of neuropathic pain and diabetic neuropathy, EPSTATE ED offers renewed hope for better symptom control and potentially slowed disease progression. The convenience of combination therapy in a single tablet improves adherence and simplifies complex treatment regimens.\nHowever, EPSTATE ED is not without considerations. Potential side effects, though generally manageable, require awareness and monitoring. The medication is most effective when integrated into a comprehensive management plan that includes optimal glycemic control, lifestyle modifications, and regular medical supervision.\nUltimately, EPSTATE ED should be viewed as a valuable tool in the therapeutic arsenal against neuropathic conditions, best utilized under the guidance of knowledgeable healthcare professionals who can individualize treatment to each patient's unique needs and circumstances. With proper use, monitoring, and patient education, EPSTATE ED can significantly improve outcomes and quality of life for those affected by these challenging neurological conditions.", "price": 275.0, "discountamount": 82.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2253, "imageuri": "https://productimages.withfloats.com/actual/694cf859d25fa0b0657b1ac8.png", "tileimageuri": "https://productimages.withfloats.com/tile/694cf859d25fa0b0657b1ac8.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-25T08:39:48.947Z", "updatedon": "2026-04-18T09:21:49.885Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//pregabalin-epalrestat-and-methylcobalamin-tablets/2253", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "EPSTATE ED", "category": "NEUROLOGYRANGE", "tags": [ "regabalin, Epalrestat, and Methylcobalamin.neuropathic pain conditions.", "Pregabalin, Epalrestat, and Methylcobalamin.", "neuropathic pain.", "diabetic neuropathy.", "sorbitol within nerve cells leads to osmotic stress.", "Epalrestat and neurotropic support via Methylcobalamin creates an environment .", "mood alterations, anxiety, depression, agitation.", "supports the neurotropic effects of Methylcobalamin.", "Pregabalin Epalrestat and Methylcobalamin Tablets", "epalrestat and methylcobalamin tablets uses", "epalrestat and methylcobalamin tablets in hindi", "pregabalin epalrestat and methylcobalamin tablets price jaipur", "pregabalin epalrestat and methylcobalamin tablets price india" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "693c0f0df827a9801a26dcd7", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Isosorbide mononitrate IP 60mg Tablets", "description": "CARDULES ISMN SR 60 delivers Isosorbide Mononitrate IP 60mg in a sustained-release tablet form, designed for long-term prevention of angina in patients with coronary artery disease. Produced by Steris Healthcare Pvt Ltd, this formulation ensures steady drug release over 12-24 hours, optimizing cardiovascular protection with once-daily dosing convenience. It supports heart health by enhancing blood flow without the peaks and troughs of immediate-release options.​\n\nProduct Overview\nCARDULES ISMN SR 60 contains Isosorbide Mononitrate IP 60mg per sustained-release tablet, a pure nitrate metabolite that bypasses first-pass liver metabolism for consistent bioavailability. The SR technology employs a polymer matrix to gradually liberate the active ingredient, maintaining therapeutic plasma levels throughout the day and minimizing tolerance development associated with frequent dosing. Available in strips of 10 tablets, it features a film-coated exterior for easy swallowing and gastro-resistant properties to protect against stomach acid degradation.​\n\nThis higher 60mg strength suits patients requiring intensified prophylaxis after initial titration from lower doses like 30mg or 40mg. It integrates seamlessly into comprehensive cardiac regimens alongside beta-blockers, statins, or aspirin, under cardiologist supervision. Quality manufacturing adheres to IP standards, ensuring purity above 99% with low impurity profiles for safety in chronic use.​\n\nKey Uses\nCARDULES ISMN SR 60 primarily prevents chronic stable angina pectoris by dilating coronary arteries and reducing myocardial oxygen demand during exertion. Patients experience fewer episodes of chest tightness, pressure, or discomfort triggered by physical activity, stress, or cold exposure.​\n\nIt manages coronary artery disease (CAD) by improving collateral circulation and easing ischemia in narrowed vessels. Often prescribed post-angioplasty or alongside lifestyle modifications, it stabilizes symptoms for enhanced daily functioning.​\n\nAdditionally, it supports adjunctive therapy in congestive heart failure or post-myocardial infarction recovery, where vasodilation unloads the heart. Not for acute attacks—use sublingual nitroglycerin instead—but vital for long-term risk reduction.​\n\nMajor Benefits\nThe sustained-release profile of CARDULE ISMN SR 60 provides 24-hour angina prevention with single morning dosing, improving adherence over multiple-daily regimens. This steady vasodilation lowers preload via venous pooling and afterload via arterial relaxation, cutting oxygen consumption by up to 20-30% during stress.​\n\nPatients report increased exercise tolerance, with treadmill tests showing delayed onset of ST-segment depression. Enhanced myocardial perfusion boosts energy levels, enabling a return to work, hobbies, or family activities without fear of sudden symptoms.​\n\nCompared to shorter-acting nitrates, tolerance buildup is slower due to a nitrate-free interval built into once-daily use. Cost-effective at higher strengths, it reduces overall healthcare visits and hospitalization risks from unstable angina.​\n\nBenefit\tMechanism\tClinical Advantage\nAngina Prevention\tVasodilation reduces preload/afterload. ​\tFewer episodes, better quality of life\nExercise Capacity\tImproved coronary flow ​\tExtended activity duration by 50%+\nDosing Simplicity\tSR once daily ​\t90% adherence rate vs. multiple doses\nHeart Protection\tLowers ischemia risk. ​\tReduced MI recurrence\nPotential Side Effects\nCommon effects include headache (orthostatic or throbbing), especially in the first week, resolving with hydration and dose acclimation—acetaminophen helps manage it. Dizziness, lightheadedness, or postural hypotension may occur; rise slowly from sitting.​\n\nGastrointestinal upset like nausea or flushing affects 5-10% initially. Avoid alcohol or PDE5 inhibitors (e.g., sildenafil) to prevent severe hypotension.​\n\nRarely, reflex tachycardia, rash, or methemoglobinemia arises; monitor liver enzymes in prolonged use. Contraindicated in severe anemia, glaucoma, or recent PDE5 intake—discontinue if allergic reactions appear.​\n\nDosage Guidelines\nInitiate at 30-40mg daily, titrating to 60mg once in the morning on an empty stomach for optimal absorption. Swallow whole; do not crush. A 10-12 hour nitrate-free window (nighttime) prevents tolerance.​\n\nAdjust for renal/hepatic impairment; max 120mg/day. Store below 25°C. Regular ECG and BP checks ensure efficacy.​\nConclusion\nCARDULES ISMN SR 60 stands as a cornerstone in angina prophylaxis, empowering CAD patients with reliable, sustained vascular relief from Steris Healthcare. Consistent use alongside diet, exercise, and smoking cessation maximizes outcomes, but cardiologist oversight remains essential for safety", "price": 155.0, "discountamount": 47.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2244, "imageuri": "https://productimages.withfloats.com/actual/693c0f14d878634fd7a965ca.png", "tileimageuri": "https://productimages.withfloats.com/tile/693c0f14d878634fd7a965ca.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-12T12:48:13.762Z", "updatedon": "2026-03-14T08:23:14.824Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//isosorbide-mononitrate-ip-60mg-tablets/2244", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CARDULES ISMN SR 60", "category": "cardiology", "tags": [ "Isosorbide mononitrate IP 60mg Tablets", "coronary artery disease", "supports heart health by enhancing blood flow", "gastro-resistant properties to protect against stomach acid", "Contraindicated in severe anemia, glaucoma, or recent PDE5", "coronary artery disease.", "It supports heart health by enhancing blood.", "isosorbide mononitrate 60mg.", "isosorbide 60mg.", "isosorbide mononitrate.", "isosorbide dinitrate tablet uses in hindi", "isosorbide", "isosorbide mononitrate uses", "isosorbide mononitrate 30 mg", "isosorbide mononitrate tablet uses in hindi" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "666ab64ed0d0330684bdba32", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "mirtazapine 7.5mg", "description": "MIRTAZPRIME 7.5 \nMirtazapine (7.5mg)\nIntroduction:\nMIRTAZPRIME 7.5 contains Mirtazapine 7.5 mg, an antidepressant medication primarily used in the management of depressive disorders and certain anxiety-related conditions. Mirtazapine belongs to a class of medicines known as noradrenergic and specific serotonergic antidepressants (NaSSAs). It works by enhancing the activity of specific neurotransmitters in the brain that regulate mood, sleep, and emotional stability.\n\nThe 7.5 mg strength is generally considered a low-dose formulation and is often used as an initial starting dose, for dose titration, or in cases where lower doses are clinically appropriate. Due to its sedative properties at lower doses, MIRTAZPRIME 7.5 is sometimes prescribed for patients who experience depression associated with sleep disturbances.\n\nMIRTAZPRIME 7.5 is intended to be used under the supervision of a qualified healthcare professional as part of a comprehensive treatment plan that may include psychological therapy, lifestyle changes, and regular monitoring.\n\nHow MIRTAZPRIME 7.5 Works\n\nMirtazapine works by influencing the levels of neurotransmitters in the brain, particularly:\n\nSerotonin – regulates mood, anxiety, and emotional balance\n\nNorepinephrine (Noradrenaline) – supports alertness, energy, and focus\n\nUnlike many other antidepressants, Mirtazapine enhances both serotonin and norepinephrine transmission through a unique mechanism. It also blocks certain histamine receptors, which contributes to its calming and sleep-promoting effects.\n\nBy restoring neurotransmitter balance, MIRTAZPRIME 7.5 helps improve mood, reduce anxiety, enhance sleep quality, and support overall mental well-being.\n\nUses of MIRTAZPRIME 7.5\n\nMIRTAZPRIME 7.5 may be prescribed for the following conditions:\n\n1. Major Depressive Disorder (MDD)\n\nMirtazapine is commonly used to treat symptoms of depression, including:\n\nPersistent sadness\n\nLoss of interest or pleasure\n\nFatigue\n\nSleep disturbances\n\nAppetite changes\n\nFeelings of hopelessness\n\nIt helps stabilize mood and gradually restore emotional functioning.\n\n2. Depression with Insomnia\n\nAt lower doses such as 7.5 mg, Mirtazapine’s sedative properties may help patients who struggle with:\n\nDifficulty falling asleep\n\nFrequent nighttime awakenings\n\nPoor sleep quality\n\nImproved sleep often plays a key role in overall recovery from depression.\n\n3. Anxiety Disorders (Off-Label Use)\n\nSome healthcare providers prescribe Mirtazapine for generalized anxiety disorder (GAD), panic disorder, or social anxiety disorder, especially when insomnia is also present.\n\n4. Appetite Stimulation in Select Patients\n\nMirtazapine may increase appetite in some individuals. In carefully selected cases, it may be used when depression is associated with weight loss or reduced appetite.\n\nKey Benefits of MIRTAZPRIME 7.5\n1. Dual Action on Mood Regulation\n\nBy enhancing both serotonin and norepinephrine activity, MIRTAZPRIME 7.5 provides comprehensive support for mood stabilization.\n\n2. Improves Sleep Quality\n\nUnlike some antidepressants that may worsen insomnia initially, low-dose Mirtazapine can promote restful sleep, making it particularly helpful for patients with sleep-related depressive symptoms.\n\n3. Reduced Sexual Side Effects\n\nCompared to certain selective serotonin reuptake inhibitors (SSRIs), Mirtazapine may have a lower risk of sexual dysfunction in some patients.\n\n4. Appetite Support\n\nFor individuals experiencing appetite loss due to depression, MIRTAZPRIME 7.5 may help restore healthy eating patterns.\n\n5. Flexible Dosing\n\nThe 7.5 mg strength allows healthcare providers to:\n\nStart treatment gradually\n\nAdjust dosage carefully\n\nMinimize initial side effects\n\nPersonalize therapy according to patient response\n\n6. Suitable for Night-Time Administration\n\nDue to its calming effects, MIRTAZPRIME 7.5 is often taken at bedtime, which can help improve adherence and nighttime comfort.\n\nDosage and Administration\n\nMIRTAZPRIME 7.5 should be taken exactly as prescribed by a healthcare professional.\n\nIt is typically taken once daily, usually at bedtime.\n\nTablets should be swallowed with water.\n\nDo not stop the medication abruptly without consulting your doctor.\n\nAntidepressants may take several weeks to show full therapeutic effects. Consistent use is important for optimal results.\n\nPossible Side Effects of MIRTAZPRIME 7.5\n\nLike all medications, MIRTAZPRIME 7.5 may cause side effects. Not everyone experiences them, and many are mild and temporary.\n\nCommon Side Effects\n\nDrowsiness or sedation\n\nIncreased appetite\n\nWeight gain\n\nDry mouth\n\nConstipation\n\nDizziness\n\nThese effects often improve as the body adjusts to the medication.\n\nMetabolic Effects\n\nLong-term use may lead to:\n\nWeight gain\n\nChanges in cholesterol levels\n\nRegular monitoring may be recommended in some patients.\n\nNeurological Effects\n\nHeadache\n\nFatigue\n\nRarely, agitation or restlessness\n\nRare but Serious Side Effects\n\nSeek immediate medical attention if you experience:\n\nSevere allergic reactions\n\nSigns of infection such as persistent fever or sore throat\n\nSuicidal thoughts or worsening depression\n\nUnusual mood changes\n\nIn rare cases, antidepressants may increase suicidal thoughts, particularly in younger individuals during early treatment phases. Close monitoring is important.\n\nPrecautions and Warnings\n\nInform your doctor if you have liver or kidney disease.\n\nUse caution if you have a history of bipolar disorder, as antidepressants may trigger mania in susceptible individuals.\n\nAvoid alcohol, as it may increase drowsiness.\n\nUse caution when driving or operating machinery until you know how the medication affects you.\n\nPregnant or breastfeeding women should consult their healthcare provider before starting MIRTAZPRIME 7.5.\n\nWho Should Avoid MIRTAZPRIME 7.5?\n\nMIRTAZPRIME 7.5 may not be suitable for individuals who:\n\nAre allergic to Mirtazapine\n\nAre taking monoamine oxidase inhibitors (MAOIs)\n\nHave severe uncontrolled liver impairment\n\nHave a history of certain blood disorders without medical supervision\n\nAlways disclose your full medical history and current medications to your healthcare provider.\n\nStorage Instructions\n\nStore at room temperature.\n\nKeep away from direct heat and moisture.\n\nKeep out of reach of children.\n\nDo not use after the expiry date printed on the package.\n\nConclusion\nMIRTAZPRIME 7.5 (Mirtazapine 7.5 mg) is a clinically established antidepressant designed to support individuals experiencing depression, particularly when accompanied by sleep disturbances or appetite changes. Its unique mechanism of action enhances serotonin and norepinephrine activity, helping restore emotional balance and improve overall mental health.\n", "price": 65.0, "discountamount": 19.5, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "day", "MDD", "mood", "food", "class", "brain", "EMAIL", "water", "45 mg", "15 mg", "tablet", "7.5 mg", "bedtime", "Benefits", "interest", "feelings", "insomnia", "patients", "response", "treatment", "same time", "chemicals", "activities", "depression", "medications", "Mirtazapine", "MIRTAZPRIME", "bloodstream", "information", "Rapid Onset", "individuals", "weight loss", "sterispharma", "hopelessness", "Introduction", "sterisonline", "Key Features", "poor appetite", "CALL/WHATSAPP", "Improved Sleep", "Initial Dosage", "anxiety levels", "Anxiety Relief", "calming effect", "Administration", "sleep patterns", "quicker relief", "anxiety symptoms", "one to two weeks", "sedative effects", "anxiety disorders", "Maintenance Dosage", "persistent sadness", "depressive symptoms", "healthcare provider", "sedative properties", "Appetite Stimulation", "other antidepressants", "typical starting dose", "usual maintenance dose", "Effective Antidepressant", "antidepressant medication", "major depressive disorder", "tetracyclic antidepressants", "consistent medication levels" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1855, "imageuri": "https://productimages.withfloats.com/actual/667d168dbd53863fb364f7ea.png", "tileimageuri": "https://productimages.withfloats.com/tile/667d168dbd53863fb364f7ea.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-13T09:05:18.43Z", "updatedon": "2026-03-12T12:03:34.972Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//mirtazapine-7-5mg/1855", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MIRTAZPRIME 7.5 ", "category": "NEUROLOGYRANGE", "tags": [ "mirtazapine warnings", "mirtazapine 7.5 uses in hindi", "mirtaz 7.5 side effects", "mirtaz 7.5 benefits", "mirtazapine for sleep", "mirtazapine 7.5mg uses", "what is mirtazapine 7.5 mg used for", "mirtazapine 7.5mg benefits", "how mirtazapine 7.5mg works", "mirtazapine 7.5mg dosage guide", "mirtazapine 7.5mg for sleep", "is mirtazapine 7.5mg effective", "mirtazapine low dose benefits", "mirtazapine 7.5mg for insomnia", "mirtazapine 7.5mg weight gain", "mirtazapine 7.5mg for elderly patients", "mirtazapine 7.5mg for stress and anxiety", "mirtazapine 7.5mg tablet price", "mirtazapine 7.5mg tablets in india", "buy mirtazapine 7.5mg online india", "mirtazapine 7.5mg generic brand", "mirtazapine 7.5mg tablet cost", "mirtazapine 7.5mg medicine information", "is mirtazapine 7.5mg enough for sleep", "how long does mirtazapine 7.5mg take to work", "can mirtazapine 7.5mg be taken daily" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "666a9bf44722330554e90097", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "LAMOTROZEN 25 ", "description": "LAMOTROZEN 25 \nLamotrigine (25mg)\nIntroduction:\n\nLAMOTROZEN 25 contains Lamotrigine (25 mg), a versatile antiepileptic medication used to treat partial-onset seizures, generalized seizures of Lennox-Gastaut syndrome, and primary generalized tonic-clonic seizures. Additionally, it is prescribed for the maintenance treatment of bipolar disorder to prevent mood episodes.\nKey Features and Benefits:\n\nSeizure Control: Lamotrigine is effective in reducing the frequency and severity of various types of seizures, including partial-onset seizures and generalized seizures, providing better control over epileptic conditions.\nBipolar Disorder Management: Lamotrigine helps prevent mood episodes in individuals with bipolar disorder, stabilizing mood and reducing the risk of extreme mood swings.\nNeurostabilization: It works by inhibiting voltage-sensitive sodium channels, which stabilizes neuronal membranes and prevents excessive neuronal firing, thereby reducing seizure activity and mood instability.\nConvenient Dosage: The 25 mg strength allows for flexible dosing schedules and adjustments as needed by healthcare providers to achieve optimal therapeutic effects.\nDosage and Administration:\n\nInitial Dosage for Epilepsy: The typical starting dose of LAMOTROZEN 25 (Lamotrigine 25 mg) is usually initiated at a low dose and gradually increased. The starting dose may vary depending on whether Lamotrigine is used alone or in combination with other antiepileptic drugs.\nInitial Dosage for Bipolar Disorder: For bipolar disorder, the initial dose is typically lower and gradually increased according to a titration schedule determined by a healthcare provider.\nMaintenance Dosage: The maintenance dose for epilepsy generally ranges from 100 mg to 500 mg per day, divided into two doses. For bipolar disorder, the maintenance dose typically ranges from 100 mg to 400 mg per day.\nAdministration: The tablet should be taken orally with water, with or without food. It is important to take Lamotrigine at the same times each day to maintain consistent medication levels in the bloodstream.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order NOW\nhttps://www.sterisonline.com/product/lamotrozen-50-134352\n", "price": 85.0, "discountamount": 25.5, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "day", "food", "risk", "EMAIL", "water", "500 mg", "400 mg", "100 mg", "tablet", "Benefits", "low dose", "severity", "Epilepsy", "two doses", "frequency", "LAMOTROZEN", "same times", "adjustments", "combination", "individuals", "bloodstream", "information", "sterispharma", "Introduction", "sterisonline", "Key Features", "initial dose", "various types", "mood episodes", "CALL/WHATSAPP", "Initial Dosage", "25 mg strength", "Administration", "Seizure Control", "seizure activity", "maintenance dose", "mood instability", "Convenient Dosage", "Lamotrigine 25 mg", "Maintenance Dosage", "titration schedule", "Neurostabilization", "neuronal membranes", "extreme mood swings", "healthcare providers", "epileptic conditions", "generalized seizures", "maintenance treatment", "typical starting dose", "partial-onset seizures", "Lennox-Gastaut syndrome", "excessive neuronal firing", "flexible dosing schedules", "other antiepileptic drugs", "Bipolar Disorder Management", "optimal therapeutic effects", "consistent medication levels", "voltage-sensitive sodium channels", "versatile antiepileptic medication", "primary generalized tonic-clonic seizures" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1844, "imageuri": "https://productimages.withfloats.com/actual/666a9bf70b4fc76a99a1fbd0.jpeg", "tileimageuri": "https://productimages.withfloats.com/tile/666a9bf70b4fc76a99a1fbd0.jpeg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-13T07:12:52.134Z", "updatedon": "2026-03-12T11:50:19.46Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//lamotrozen-25-/1844", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "LAMOTROZEN 25 ", "category": "NEUROLOGYRANGE", "tags": [ "Lamotrigine (25mg)", "", "lamotrigine side effects", "lamotrigine side effects weight gain", "lamictal weight gain reviews", "lamotrigine uses" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "666a99b5c91739182c956027", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "LAMOTRIZ 50 ", "description": "LAMOTRIZ 50 \nLamotrigine Dispersible 50\nIntroduction:\n\nLAMOTRIZ 50 contains Lamotrigine Dispersible (50 mg), a versatile antiepileptic medication used to treat partial-onset seizures, generalized seizures of Lennox-Gastaut syndrome, and primary generalized tonic-clonic seizures. Additionally, it is prescribed for the maintenance treatment of bipolar disorder to prevent mood episodes.\nKey Features and Benefits:\n\nSeizure Control: Lamotrigine is effective in reducing the frequency and severity of various types of seizures, including partial-onset seizures and generalized seizures, providing better control over epileptic conditions.\nBipolar Disorder Management: Lamotrigine helps prevent mood episodes in individuals with bipolar disorder, stabilizing mood and reducing the risk of extreme mood swings.\nNeurostabilization: It works by inhibiting voltage-sensitive sodium channels, which stabilizes neuronal membranes and prevents excessive neuronal firing, thereby reducing seizure activity and mood instability.\nDispersible Tablet: The dispersible formulation of Lamotrigine makes it easier to administer, especially for individuals who have difficulty swallowing tablets. It can be dissolved in water or placed on the tongue to dissolve.\nDosage and Administration:\n\nInitial Dosage for Epilepsy: The typical starting dose of LAMOTRIZ 50 (Lamotrigine Dispersible 50 mg) is usually initiated at a low dose and gradually increased. The starting dose may vary depending on whether Lamotrigine is used alone or in combination with other antiepileptic drugs.\nInitial Dosage for Bipolar Disorder: For bipolar disorder, the initial dose is typically lower and gradually increased according to a titration schedule determined by a healthcare provider.\nMaintenance Dosage: The maintenance dose for epilepsy generally ranges from 100 mg to 500 mg per day, divided into two doses. For bipolar disorder, the maintenance dose typically ranges from 100 mg to 400 mg per day.\nAdministration: The dispersible tablet should be placed on the tongue to dissolve or mixed with a small amount of water before swallowing. It can be taken with or without food.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order NOW\nhttps://www.sterisonline.com/product/lamotriz-50-133579", "price": 108.8, "discountamount": 32.64, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "day", "risk", "food", "EMAIL", "water", "100 mg", "500 mg", "400 mg", "tongue", "tablets", "product", "low dose", "severity", "Benefits", "LAMOTRIZ", "Epilepsy", "frequency", "two doses", "difficulty", "individuals", "combination", "information", "sterisonline", "Introduction", "sterispharma", "small amount", "Key Features", "initial dose", "CALL/WHATSAPP", "various types", "mood episodes", "Initial Dosage", "Administration", "Seizure Control", "mood instability", "seizure activity", "maintenance dose", "neuronal membranes", "Dispersible Tablet", "titration schedule", "Maintenance Dosage", "Neurostabilization", "extreme mood swings", "healthcare provider", "generalized seizures", "epileptic conditions", "typical starting dose", "maintenance treatment", "partial-onset seizures", "dispersible formulation", "Lennox-Gastaut syndrome", "excessive neuronal firing", "other antiepileptic drugs", "Bipolar Disorder Management", "Lamotrigine Dispersible 50 mg", "voltage-sensitive sodium channels", "versatile antiepileptic medication", "primary generalized tonic-clonic seizures" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1843, "imageuri": "https://productimages.withfloats.com/actual/666a99b84b514c761a3042cc.jpg", "tileimageuri": "https://productimages.withfloats.com/tile/666a99b84b514c761a3042cc.jpg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-13T07:03:17.643Z", "updatedon": "2026-03-17T07:37:51.689Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//lamotriz-50-/1843", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "LAMOTRIZ 50 ", "category": "NEUROLOGYRANGE", "tags": [ "LAMOTRIZ 50", "", "Lamotrigine Dispersible 50", "", "lamotrigine 50 mg uses", "lamotrigine side effects", "lamotrigine side effects weight gain", "bipolar weight gain solutions" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false } ], "hasmoreitems": false, "isapirequest": false, "totalresults": 27, "query": null, "floatingpoint": null }