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{ "products": [ { "_id": "693c0f0df827a9801a26dcd7", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Isosorbide mononitrate IP 60mg Tablets", "description": "CARDULES ISMN SR 60 delivers Isosorbide Mononitrate IP 60mg in a sustained-release tablet form, designed for long-term prevention of angina in patients with coronary artery disease. Produced by Steris Healthcare Pvt Ltd, this formulation ensures steady drug release over 12-24 hours, optimizing cardiovascular protection with once-daily dosing convenience. It supports heart health by enhancing blood flow without the peaks and troughs of immediate-release options.​\n\nProduct Overview\nCARDULES ISMN SR 60 contains Isosorbide Mononitrate IP 60mg per sustained-release tablet, a pure nitrate metabolite that bypasses first-pass liver metabolism for consistent bioavailability. The SR technology employs a polymer matrix to gradually liberate the active ingredient, maintaining therapeutic plasma levels throughout the day and minimizing tolerance development associated with frequent dosing. Available in strips of 10 tablets, it features a film-coated exterior for easy swallowing and gastro-resistant properties to protect against stomach acid degradation.​\n\nThis higher 60mg strength suits patients requiring intensified prophylaxis after initial titration from lower doses like 30mg or 40mg. It integrates seamlessly into comprehensive cardiac regimens alongside beta-blockers, statins, or aspirin, under cardiologist supervision. Quality manufacturing adheres to IP standards, ensuring purity above 99% with low impurity profiles for safety in chronic use.​\n\nKey Uses\nCARDULES ISMN SR 60 primarily prevents chronic stable angina pectoris by dilating coronary arteries and reducing myocardial oxygen demand during exertion. Patients experience fewer episodes of chest tightness, pressure, or discomfort triggered by physical activity, stress, or cold exposure.​\n\nIt manages coronary artery disease (CAD) by improving collateral circulation and easing ischemia in narrowed vessels. Often prescribed post-angioplasty or alongside lifestyle modifications, it stabilizes symptoms for enhanced daily functioning.​\n\nAdditionally, it supports adjunctive therapy in congestive heart failure or post-myocardial infarction recovery, where vasodilation unloads the heart. Not for acute attacks—use sublingual nitroglycerin instead—but vital for long-term risk reduction.​\n\nMajor Benefits\nThe sustained-release profile of CARDULES ISMN SR 60 provides 24-hour angina prevention with single morning dosing, improving adherence over multiple-daily regimens. This steady vasodilation lowers preload via venous pooling and afterload via arterial relaxation, cutting oxygen consumption by up to 20-30% during stress.​\n\nPatients report increased exercise tolerance, with treadmill tests showing delayed onset of ST-segment depression. Enhanced myocardial perfusion boosts energy levels, enabling return to work, hobbies, or family activities without fear of sudden symptoms.​\n\nCompared to shorter-acting nitrates, tolerance buildup is slower due to a nitrate-free interval built into once-daily use. Cost-effective at higher strengths, it reduces overall healthcare visits and hospitalization risks from unstable angina.​\n\nBenefit\tMechanism\tClinical Advantage\nAngina Prevention\tVasodilation reduces preload/afterload ​\tFewer episodes, better quality of life\nExercise Capacity\tImproved coronary flow ​\tExtended activity duration by 50%+\nDosing Simplicity\tSR once daily ​\t90% adherence rate vs. multiple doses\nHeart Protection\tLowers ischemia risk. ​\tReduced MI recurrence\nPotential Side Effects\nCommon effects include headache (orthostatic or throbbing), especially in the first week, resolving with hydration and dose acclimation—acetaminophen helps manage it. Dizziness, lightheadedness, or postural hypotension may occur; rise slowly from sitting.​\n\nGastrointestinal upset like nausea or flushing affects 5-10% initially. Avoid alcohol or PDE5 inhibitors (e.g., sildenafil) to prevent severe hypotension.​\n\nRarely, reflex tachycardia, rash, or methemoglobinemia arises; monitor liver enzymes in prolonged use. Contraindicated in severe anemia, glaucoma, or recent PDE5 intake—discontinue if allergic reactions appear.​\n\nDosage Guidelines\nInitiate at 30-40mg daily, titrating to 60mg once in the morning on an empty stomach for optimal absorption. Swallow whole; do not crush. A 10-12 hour nitrate-free window (nighttime) prevents tolerance.​\n\nAdjust for renal/hepatic impairment; max 120mg/day. Store below 25°C. Regular ECG and BP checks ensure efficacy.​\nConclusion\nCARDULES ISMN SR 60 stands as a cornerstone in angina prophylaxis, empowering CAD patients with reliable, sustained vascular relief from Steris Healthcare. Consistent use alongside diet, exercise, and smoking cessation maximizes outcomes, but cardiologist oversight remains essential for safety", "price": 155.0, "discountamount": 47.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2244, "imageuri": "https://productimages.withfloats.com/actual/693c0f14d878634fd7a965ca.png", "tileimageuri": "https://productimages.withfloats.com/tile/693c0f14d878634fd7a965ca.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-12T12:48:13.762Z", "updatedon": "2025-12-16T05:41:10.59Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/isosorbide-mononitrate-ip-60mg-tablets/2244", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CARDULES ISMN SR 60", "category": "cardiology", "tags": [ "Isosorbide mononitrate IP 60mg Tablets", "coronary artery disease", "supports heart health by enhancing blood flow", "gastro-resistant properties to protect against stomach acid", "Contraindicated in severe anemia, glaucoma, or recent PDE5" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6917218c6e3de7f45cff9997", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Gabapentin and Lidocaine Hydrochloride Gel ", "description": "Gabapentin and Lidocaine Hydrochloride is a specialized combination therapy primarily used to manage neuropathic pain—pain resulting from nerve damage, irritation, or dysfunction. This blend unites two highly effective agents: gabapentin, an anticonvulsant widely used for nerve-related pain, and lidocaine hydrochloride, a fast-acting local anesthetic that numbs nerve signals in targeted areas. Together, they deliver both systemic and localized pain relief, making the product ideal for patients seeking comprehensive control of chronic or acute neuropathic symptoms.\n\nThis combination may appear in different formulations, such as topical creams, patches, or oral gabapentin used alongside lidocaine topical therapy. The synergistic action makes it especially beneficial for individuals who do not achieve adequate relief from a single medication. By addressing pain through two different mechanisms—central nerve modulation (gabapentin) and peripheral nerve numbing (lidocaine)—this combination delivers a balanced approach to pain management with reduced need for stronger systemic medications.\n\nGabapentin works by calming overactive nerve signals in the central nervous system. It binds to calcium channels in the brain and spinal cord, reducing the abnormal firing responsible for neuropathic discomfort. Lidocaine, on the other hand, blocks sodium channels in peripheral nerves, preventing pain signals from traveling to the brain. Together, they create a powerful relief profile suitable for various nerve-related conditions.\n\nUses of Gabapentin and Lidocaine Hydrochloride\n\nThis combination is commonly recommended for patients dealing with complex nerve pain. Typical uses include:\n\n1. Neuropathic Pain\n\nIdeal for conditions such as:\n\nPeripheral neuropathy\n\nDiabetic neuropathy\n\nChemotherapy-induced neuropathy\n\nPost-surgical nerve pain\n\n2. Postherpetic Neuralgia (PHN)\n\nPatients recovering from shingles often experience burning, sharp, or stabbing nerve pain. Lidocaine patches offer localized relief, while gabapentin reduces the intensity of nerve signaling.\n\n3. Sciatica and Radicular Pain\n\nWhen pain radiates from the spine to the legs or arms due to nerve compression, this combination offers both deep and surface-level relief.\n\n4. Fibromyalgia\n\nGabapentin may reduce widespread nerve sensitivity, while lidocaine provides targeted relief in high-pain areas.\n\n5. Localized Musculoskeletal or Joint Pain With Nerve Involvement\n\nLidocaine can temporarily numb sensitive regions, while gabapentin addresses chronic nerve irritation.\n\nKey Benefits\n1. Dual-Action Pain Relief\n\nGabapentin works internally to stabilize nerve activity, while lidocaine provides immediate external numbing. This dual approach addresses pain from both ends.\n\n2. Reduced Need for Strong Systemic Painkillers\n\nMany patients experience significant relief without relying on opioids or sedatives.\n\n3. Rapid Onset from Lidocaine\n\nTopical lidocaine begins relieving pain within minutes by blocking peripheral nerve transmission.\n\n4. Long-Term Nerve Modulation from Gabapentin\n\nGabapentin’s central action builds gradually, offering sustained reduction of chronic nerve pain with consistent use.\n\n5. Versatile Application\n\nThe combination can be tailored to individual needs—oral gabapentin for long-term control and lidocaine patches or gel for targeted, immediate comfort.\n\n6. Improved Daily Function\n\nBy reducing constant nerve irritation, patients often regain mobility, sleep quality, and overall comfort.\n\nPossible Side Effects\nGabapentin Side Effects\n\nCommon:\n\nDizziness\n\nDrowsiness\n\nFatigue\n\nMild swelling in the legs\n\nCoordination problems\n\nLess common but important:\n\nMood changes\n\nBlurred vision\n\nDifficulty concentrating\n\nLidocaine Hydrochloride Side Effects\n\nCommon:\n\nSkin redness or irritation\n\nTemporary numbness\n\nMild burning or itching at application site\n\nRare but serious:\n\nAllergic reactions\n\nIrregular heartbeat (with excessive use)\n\nSystemic toxicity if large amounts are absorbed\n\nPatients should follow dosing instructions carefully and avoid applying lidocaine to broken skin unless instructed.\n\nConclusion\n\nThe combination of Gabapentin and Lidocaine Hydrochloride represents a powerful and effective solution for individuals struggling with neuropathic pain. By blending the internal nerve-calming effects of gabapentin with the fast-acting local numbing properties of lidocaine, this therapy covers multiple pain pathways simultaneously. It offers significant relief for conditions such as diabetic neuropathy, shingles-related pain, nerve compression syndromes, and chronic nerve-related disorders.", "price": 250.0, "discountamount": 75.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2206, "imageuri": "https://productimages.withfloats.com/actual/6917218e632ad4b43b4993ca.png", "tileimageuri": "https://productimages.withfloats.com/tile/6917218e632ad4b43b4993ca.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-14T12:33:16.079Z", "updatedon": "2025-12-09T05:58:50.543Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/gabapentin-and-lidocaine-hydrochloride-gel-/2206", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Steris Healthcare Pvt Ltd", "category": "NEUROLOGY", "tags": [ "Gabapentin and Lidocaine Hydrochloride", "neuropathic pain", "nerve damage", "bladder dysfunctions.", "neuropathic symptoms" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69142bf71d499513a92e5772", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Nicorandil Tablets 5mg", "description": "Nicorandil Tablets 5 mg is a vasodilatory anti-anginal medication widely prescribed for the management and prevention of angina pectoris (chest pain) associated with coronary artery disease (CAD). Angina results from an imbalance between the heart’s oxygen demand and supply due to restricted blood flow in the coronary arteries. Nicorandil offers a dual mechanism of action — acting both as a nitrate-like vasodilator and a potassium channel opener, making it unique among anti-anginal agents.\n\nBy improving oxygen delivery to the myocardium and reducing cardiac workload, Nicorandil 5 mg Tablets provide effective relief from anginal pain and reduce the frequency and severity of ischemic episodes. It is also beneficial in preventing future attacks, improving exercise tolerance, and enhancing the overall quality of life in patients with chronic stable angina.\n\nComposition\n\nEach tablet contains:\n\nNicorandil IP – 5 mg\n\nExcipients – q.s.\n\nNicorandil tablets are available in film-coated form to ensure stability, easy swallowing, and optimal absorption. They are manufactured in compliance with Good Manufacturing Practices (GMP) standards to ensure safety, purity, and efficacy.\n\nPharmacological Action / Mechanism of Action\n\nNicorandil exhibits a dual mechanism that makes it distinct among anti-anginal drugs:\n\nNitrate-Like Effect:\nNicorandil acts as a nitric oxide (NO) donor. Nitric oxide activates guanylate cyclase, increasing cyclic GMP (cGMP) levels in vascular smooth muscle. This leads to relaxation of blood vessels, particularly veins and large arteries, thereby reducing preload and afterload on the heart. This nitrate-like activity lowers myocardial oxygen demand.\n\nPotassium Channel Opening Effect:\nNicorandil opens ATP-sensitive potassium (KATP) channels in vascular smooth muscle, resulting in arteriolar vasodilation. This increases coronary blood flow and improves oxygen supply to ischemic heart tissues.\n\nTogether, these effects reduce cardiac workload, enhance coronary perfusion, and prevent anginal pain by correcting the oxygen supply-demand mismatch in the heart muscle.\n\nUses and Indications\n\nNicorandil Tablets 5 mg are indicated for the treatment and prevention of angina pectoris in adults, particularly:\n\nChronic Stable Angina:\n\nHelps reduce the frequency and severity of chest pain associated with exertion or emotional stress.\n\nProphylaxis of Angina Attacks:\n\nUsed regularly to prevent anginal episodes, especially in patients with known coronary artery disease.\n\nAdjunct Therapy in Ischemic Heart Disease (IHD):\n\nCan be used alongside beta-blockers, calcium channel blockers, or antiplatelet drugs for enhanced symptom control and long-term protection.\n\nImprovement of Exercise Tolerance:\n\nReduces the likelihood of anginal pain during physical activity, enabling patients to perform daily tasks comfortably.\n\nIn some clinical cases, Nicorandil is also considered for post-myocardial infarction recovery, as it improves coronary perfusion, although this is at the discretion of a cardiologist.\n\nDosage and Administration\n\nRecommended Starting Dose: 5 mg to 10 mg twice daily.\n\nMaintenance Dose: May be increased gradually to 10–20 mg twice daily, depending on clinical response and tolerance.\n\nThe tablets should be swallowed whole with water, preferably at the same times each day.\n\nNicorandil should not be stopped abruptly; dosage tapering is recommended to avoid rebound angina.\n\nAlways follow the dosage instructions provided by the physician.\n\nKey Benefits\n\nDual Mechanism for Comprehensive Relief:\nCombines nitrate-like and potassium channel-opening properties for both arterial and venous dilation, providing superior protection against anginal attacks.\n\nImproves Coronary Blood Flow:\nDilates coronary arteries, increasing oxygen delivery to ischemic myocardial tissues.\n\nReduces Cardiac Workload:\nBy decreasing preload (venous return) and afterload (arterial resistance), Nicorandil minimizes the heart’s oxygen consumption.\n\nRapid Onset of Action:\nNicorandil acts within a short duration, offering quick relief from anginal discomfort.\n\nPrevents Future Angina Episodes:\nRegular use helps maintain steady control of chest pain, improving exercise capacity and quality of life.\n\nCompatible with Other Cardiac Medications:\nCan be safely used alongside antiplatelet agents, beta-blockers, ACE inhibitors, and statins as part of comprehensive cardiac care.\n\nFavorable Safety Profile:\nCompared to nitrates, Nicorandil carries a lower risk of tolerance development, making it suitable for long-term therapy.\n\nEnhances Myocardial Protection:\nNicorandil’s KATP channel activation provides additional cardioprotective effects by improving microvascular blood flow and limiting ischemic damage during stress.\n\nPrecautions and Warnings\n\nAlthough Nicorandil is generally well-tolerated, certain precautions are advised:\n\nHypotension:\nNicorandil may cause a drop in blood pressure due to vasodilation. Caution is advised in patients with hypotension or dehydration.\n\nConcurrent Use with Nitrates:\nShould not be used together with other nitrate medications to avoid severe hypotension.\n\nOral or Gastrointestinal Ulcers:\nRarely, Nicorandil may cause ulcerations in the mouth, intestines, or skin. Treatment should be discontinued if ulceration occurs.\n\nPatients with Low Blood Volume:\nUse cautiously in individuals with hypovolemia or those on diuretics.\n\nDriving and Machinery:\nDizziness or light-headedness may occur; avoid driving until effects are known.\n\nPregnancy and Lactation:\nShould be used only if prescribed by a physician when the potential benefits outweigh the risks.\n\nPossible Side Effects\n\nNicorandil is generally safe but may cause some side effects, particularly at the start of therapy or with higher doses. Common and rare adverse reactions include:\n\nCommon Side Effects:\n\nHeadache (due to vasodilation)\n\nFlushing or warmth sensation\n\nDizziness or light-headedness\n\nNausea or mild stomach upset\n\nFatigue or weakness\n\nLess Common / Rare Side Effects:\n\nHypotension (low blood pressure)\n\nPalpitations or tachycardia\n\nMouth ulcers, anal ulcers, or skin ulceration (uncommon but serious — discontinue if occurs)\n\nRash or allergic reaction\n\nVisual disturbances (rare and usually reversible)\n\nIf any severe reaction or persistent discomfort occurs, medical attention should be sought promptly.\n\nDrug Interactions\n\nAvoid concomitant use with nitrates or phosphodiesterase type-5 inhibitors (e.g., Sildenafil, Tadalafil), as it may cause a dangerous fall in blood pressure.\n\nCaution with antihypertensive drugs or diuretics, which may enhance hypotensive effects.\n\nAlcohol consumption can potentiate dizziness or hypotension and should be limited.\n\nStorage and Handling\n\nStore below 30°C, protected from moisture and direct sunlight.\n\nKeep out of reach of children.\n\nDo not use tablets past the expiry date or if the packaging is damaged.\n\nConclusion\n\nNicorandil Tablets 5 mg offer a modern and effective approach to managing angina pectoris, providing reliable relief through their dual-action mechanism. By combining nitrate-like vasodilation with potassium channel opening, Nicorandil ensures both oxygen supply improvement and reduction of cardiac workload — the cornerstone of angina management.\n\nIt is well-tolerated, fast-acting, and suitable for long-term therapy, making it a preferred choice for patients with chronic stable angina. Regular use under medical supervision helps reduce the frequency of chest pain, improve physical endurance, and enhance the overall quality of life in individuals with coronary artery disease.", "price": 381.0, "discountamount": 115.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2202, "imageuri": "https://productimages.withfloats.com/actual/69142c03b53db80943abd33d.png", "tileimageuri": "https://productimages.withfloats.com/tile/69142c03b53db80943abd33d.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-12T06:40:55.795Z", "updatedon": "2025-12-09T05:59:32.564Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/nicorandil-tablets-5mg/2202", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MAYORANDIL 5 ", "category": "CARDIOLOGYRANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "666c09b805b00e1ad41ca790", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Topiramate 50mg", "description": "TP MATE 50 \nTopiramate (50mg)\nIntroduction:\nTP MATE 50 contains Topiramate, a versatile anticonvulsant and migraine prophylactic medication. With a dosage strength of 50mg, TP MATE 50 is designed to manage seizures in epilepsy and prevent migraines, significantly enhancing the quality of life for patients.\nKey Features and Benefits:\nAnticonvulsant Action:\nTP MATE 50 is highly effective in treating various types of seizures, including partial-onset seizures, generalized tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome. It stabilizes neuronal activity by enhancing GABAergic transmission, blocking sodium channels, and inhibiting glutamate activity.\nMigraine Prophylaxis:\n\nTopiramate is widely used for preventing migraines. By modulating neurotransmitter activity, TP MATE 50 reduces the frequency and severity of migraine attacks, helping patients manage their condition and improve their daily functioning.\nWeight Management:\n\nAn added benefit of TP MATE 50 is its potential to assist with weight loss. Unlike many anticonvulsants, Topiramate may lead to weight reduction, which can be beneficial for patients concerned about weight gain associated with other medications.\nMood Stabilization:\n\nTopiramate has mood-stabilizing properties, making it useful for patients with coexisting mood disorders such as bipolar disorder. It helps in stabilizing mood swings and reducing symptoms of anxiety and depression.\nWell-Tolerated and Safe:\n\nTP MATE 50 is generally well-tolerated with a favorable safety profile, making it a reliable option for long-term management of epilepsy and migraines.\nDosage and Administration:\n\nInitial Dosage for Epilepsy:\n\nThe initial dose of TP MATE 50 for adults with epilepsy typically starts at a low dose, gradually increasing to reduce the risk of side effects. A common starting dose is 25-50mg per day, increasing weekly by 25-50mg until the effective dose is reached. The usual maintenance dose ranges from 200-400mg per day, divided into two doses.\nInitial Dosage for Migraine Prophylaxis:\n\nFor migraine prevention, the initial dose is 25mg taken once daily, usually at night. The dose may be increased weekly by 25mg, up to a recommended dose of 50-100mg per day, divided into two doses.\nAdministration Instructions:\n\nTP MATE 50 tablets should be taken orally with or without food. It is important to maintain consistent dosing schedules to ensure stable therapeutic levels.\nContinued Monitoring:\n\nRegular monitoring of seizure frequency, migraine attacks, and potential side effects is essential during TP MATE 50 therapy to ensure therapeutic efficacy and patient safety.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order NOW \n", "price": 92.0, "discountamount": 28.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "day", "life", "food", "50mg", "25mg", "risk", "EMAIL", "night", "option", "adults", "anxiety", "quality", "symptoms", "severity", "50-100mg", "low dose", "epilepsy", "patients", "Benefits", "200-400mg", "two doses", "condition", "migraines", "Topiramate", "depression", "mood swings", "weight gain", "weight loss", "information", "Key Features", "sterispharma", "Introduction", "initial dose", "sterisonline", "CALL/WHATSAPP", "added benefit", "various types", "mood disorders", "patient safety", "Initial Dosage", "effective dose", "sodium channels", "dosage strength", "migraine attacks", "bipolar disorder", "weight reduction", "neuronal activity", "seizure frequency", "daily functioning", "other medications", "Weight Management", "Regular monitoring", "Mood Stabilization", "TP MATE 50 therapy", "glutamate activity", "TP MATE 50 tablets", "migraine prevention", "long-term management", "Migraine Prophylaxis", "Continued Monitoring", "common starting dose", "many anticonvulsants", "therapeutic efficacy", "Anticonvulsant Action", "usual maintenance dose", "potential side effects", "partial-onset seizures", "GABAergic transmission", "Lennox-Gastaut syndrome", "favorable safety profile", "versatile anticonvulsant", "neurotransmitter activity", "stable therapeutic levels", "Administration Instructions", "mood-stabilizing properties", "consistent dosing schedules", "migraine prophylactic medication", "generalized tonic-clonic seizures" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1905, "imageuri": "https://productimages.withfloats.com/actual/666c09bbf068be46bdec8995.png", "tileimageuri": "https://productimages.withfloats.com/tile/666c09bbf068be46bdec8995.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-14T09:13:28.046Z", "updatedon": "2025-12-17T05:54:34.575Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/topiramate-50mg/1905", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "TP MATE 50 ", "category": "NEUROLOGY RANGE", "tags": [ "TP MATE 50", "", "Topiramate (50mg)", "topiramate uses", "topiramate 50 mg", "topiramate side effects", "topiramate side effects weight loss" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "666c08e7c91739182c9574b6", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "TP MATE 100 ", "description": "TP MATE 100 \nTopiramate (100mg)\nIntroduction:\n\nTP MATE 100 contains Topiramate, a broad-spectrum anticonvulsant and migraine prophylactic medication. With a dosage strength of 100mg, TP MATE 100 is designed to manage seizures in epilepsy and prevent migraines, significantly enhancing the quality of life for patients.\nKey Features and Benefits:\n\nAnticonvulsant Action:\n\nTP MATE 100 is highly effective in treating various types of seizures, including partial-onset seizures, generalized tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome. It stabilizes neuronal activity by enhancing GABAergic transmission, blocking sodium channels, and inhibiting glutamate activity.\nMigraine Prophylaxis:\n\nTopiramate is widely used for preventing migraines. By modulating neurotransmitter activity, TP MATE 100 reduces the frequency and severity of migraine attacks, helping patients manage their condition and improve their daily functioning.\nWeight Management:\n\nAn added benefit of TP MATE 100 is its potential to assist with weight loss. Unlike many anticonvulsants, Topiramate may lead to weight reduction, which can be beneficial for patients concerned about weight gain associated with other medications.\nMood Stabilization:\n\nTopiramate has mood-stabilizing properties, making it useful for patients with coexisting mood disorders such as bipolar disorder. It helps in stabilizing mood swings and reducing symptoms of anxiety and depression.\nWell-Tolerated and Safe:\n\nTP MATE 100 is generally well-tolerated with a favorable safety profile, making it a reliable option for long-term management of epilepsy and migraines.\nDosage and Administration:\n\nInitial Dosage for Epilepsy:\n\nThe initial dose of TP MATE 100 for adults with epilepsy typically starts at a low dose, gradually increasing to reduce the risk of side effects. A common starting dose is 25-50mg per day, increasing weekly by 25-50mg until the effective dose is reached. The usual maintenance dose ranges from 200-400mg per day, divided into two doses.\nInitial Dosage for Migraine Prophylaxis:\n\nFor migraine prevention, the initial dose is 25mg taken once daily, usually at night. The dose may be increased weekly by 25mg, up to a recommended dose of 100mg per day, divided into two doses.\nAdministration Instructions:\n\nTP MATE 100 tablets should be taken orally with or without food. It is important to maintain consistent dosing schedules to ensure stable therapeutic levels.\nContinued Monitoring:\n\nRegular monitoring of seizure frequency, migraine attacks, and potential side effects is essential during TP MATE 100 therapy to ensure therapeutic efficacy and patient safety.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order NOW \nhttps://www.sterisonline.com/product/tp-mate-100-133633", "price": 149.0, "discountamount": 44.7, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "day", "life", "food", "25mg", "risk", "50mg", "EMAIL", "night", "100mg", "option", "adults", "anxiety", "quality", "symptoms", "severity", "low dose", "epilepsy", "patients", "Benefits", "200-400mg", "two doses", "condition", "migraines", "Topiramate", "depression", "mood swings", "weight gain", "weight loss", "information", "Key Features", "sterispharma", "Introduction", "initial dose", "sterisonline", "CALL/WHATSAPP", "added benefit", "various types", "mood disorders", "patient safety", "Initial Dosage", "effective dose", "sodium channels", "dosage strength", "migraine attacks", "bipolar disorder", "weight reduction", "neuronal activity", "seizure frequency", "daily functioning", "other medications", "Weight Management", "Regular monitoring", "Mood Stabilization", "glutamate activity", "migraine prevention", "TP MATE 100 therapy", "TP MATE 100 tablets", "long-term management", "Migraine Prophylaxis", "Continued Monitoring", "common starting dose", "many anticonvulsants", "therapeutic efficacy", "Anticonvulsant Action", "usual maintenance dose", "potential side effects", "partial-onset seizures", "GABAergic transmission", "Lennox-Gastaut syndrome", "favorable safety profile", "neurotransmitter activity", "stable therapeutic levels", "Administration Instructions", "mood-stabilizing properties", "consistent dosing schedules", "broad-spectrum anticonvulsant", "migraine prophylactic medication", "generalized tonic-clonic seizures" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1904, "imageuri": "https://productimages.withfloats.com/actual/666c08eb0b4fc76a99a41986.png", "tileimageuri": "https://productimages.withfloats.com/tile/666c08eb0b4fc76a99a41986.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-14T09:09:59.43Z", "updatedon": "2024-06-26T06:09:24.07Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/tp-mate-100-/1904", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "TP MATE 100 ", "category": "NEUROLOGY RANGE", "tags": [ "tp mate 100 tablet price", "topiramate side effects weight loss", "topiramate side effects", "tp mate 100 tablet in hindi language" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "66541ca7329f8d125c490814", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "AMIDRONE 200", "description": "AMIDRONE 200\nAmiodarone 200mg\nAMIDRONE 200, containing Amiodarone (200mg), is a highly effective antiarrhythmic medication designed to stabilize heart rhythms. It's particularly crucial for patients with potentially fatal arrhythmias where other treatments might have failed.\n\nUses:\nThis medication is primarily used to treat severe ventricular arrhythmias such as ventricular tachycardia and ventricular fibrillation. It is also effective against atrial fibrillation and other serious supraventricular arrhythmias that do not respond to other medications.\n\nDosage:\nTreatment typically starts with a high initial dose ranging from 800 to 1600 mg daily for 1 to 3 weeks until a response is achieved, followed by a gradual reduction to maintenance levels of 200 to 400 mg per day as directed by a healthcare provider.\n\nSide Effects:\nCommon side effects of AMIDRONE 200 include nausea, fatigue, and tremors. Serious potential side effects involve lung and liver toxicity, vision issues, and skin changes. Long-term use may lead to thyroid dysfunction or neurological effects.\n\nPrecautions:\nPatients on AMIDRONE 200 should have regular monitoring of heart function, liver enzymes, lung function, and thyroid function tests. This medication should be used with caution in combination with other drugs that can affect the heart rhythm. Patients should avoid grapefruit juice and excessive sunlight due to interactions and increased risk of sunburn.\n\nConclusion:\nAMIDRONE 200 is a cornerstone in the management of severe arrhythmias, requiring careful oversight and regular follow-ups to manage its complex side effect profile effectively. It's vital for patients to maintain close communication with their healthcare providers to ensure safe and effective treatment.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order NOW\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order NOW\n", "price": 120.0, "discountamount": 36.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "800", "day", "risk", "Uses", "safe", "200mg", "Dosage", "nausea", "1600 mg", "sunburn", "tremors", "fatigue", "AMIDRONE", "patients", "response", "Conclusion", "Amiodarone", "management", "Precautions", "combination", "cornerstone", "other drugs", "interactions", "1 to 3 weeks", "skin changes", "200 to 400 mg", "lung function", "liver enzymes", "vision issues", "heart rhythms", "Long-term use", "liver toxicity", "heart function", "grapefruit juice", "other treatments", "gradual reduction", "fatal arrhythmias", "other medications", "high initial dose", "careful oversight", "maintenance levels", "regular follow-ups", "excessive sunlight", "severe arrhythmias", "regular monitoring", "atrial fibrillation", "Common side effects", "healthcare provider", "effective treatment", "close communication", "thyroid dysfunction", "neurological effects", "thyroid function tests", "ventricular tachycardia", "ventricular fibrillation", "complex side effect profile", "Serious potential side effects", "severe ventricular arrhythmias", "effective antiarrhythmic medication", "other serious supraventricular arrhythmias" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1154, "imageuri": "https://productimages.withfloats.com/actual/667d2d5d000f6c164f095062.png", "tileimageuri": "https://productimages.withfloats.com/tile/667d2d5d000f6c164f095062.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-05-27T05:39:51.591Z", "updatedon": "2025-12-04T12:17:34.566Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/amidrone-200/1154", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Amiodarone (200mg)", "category": "CARDIOLOGYRANGE", "tags": [ "Amiodarone 200 mg uses", "Amiodarone uses", "Amiodarone dosage 200 mg", "Is 200 mg of amiodarone a lot", "Amiodarone 200 mg price", "Amiodarone side effects", "Side effects of amiodarone 200 mg", "" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6943af86161ad9de85f42b10", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Imatinib IP 400mg", "description": "IMATIFLOW 400, containing Imatinib IP 400mg, represents a breakthrough in targeted cancer therapy, offering patients a precise weapon against specific malignancies. This oral medication belongs to the class of tyrosine kinase inhibitors, revolutionizing treatment for conditions once deemed challenging to manage. By blocking abnormal proteins that fuel cancer cell growth, IMATIFLOW 400 helps restore normal cellular function and improves quality of life for many users.​\n\nProduct Overview\nIMATIFLOW 400 is a branded formulation of Imatinib mesylate 400mg, produced to high pharmaceutical standards for consistent efficacy and bioavailability. Each tablet delivers the active ingredient in a film-coated form, designed for once-daily administration with food to enhance absorption and minimize gastrointestinal upset. Developed for adult patients, it targets cancers driven by dysregulated tyrosine kinases like BCR-ABL, c-KIT, and PDGFR, making it a cornerstone in modern oncology protocols.​\n\nThe medication's mechanism hinges on competitive inhibition at the ATP-binding site of these kinases, halting downstream signaling pathways that promote uncontrolled proliferation, survival, and metastasis of malignant cells. Unlike traditional chemotherapy, which broadly attacks dividing cells, IMATIFLOW 400 spares most healthy tissues, leading to a more favorable safety profile. Clinical data from pivotal trials underscore its role as first-line therapy, with high response rates observed within months of initiation.​\n\nPrimary Uses\nIMATIFLOW 400 excels in treating chronic myeloid leukemia (CML), particularly in the chronic phase where it induces deep molecular responses in over 80% of patients. It suppresses the Philadelphia chromosome-positive cells hallmark of CML by inhibiting the BCR-ABL fusion protein, dramatically extending progression-free survival. For newly diagnosed patients, standard dosing starts at 400mg daily, often achieving complete cytogenetic remission.​\n\nIn gastrointestinal stromal tumors (GIST), IMATIFLOW 400 targets KIT or PDGFRA mutations, shrinking unresectable tumors and delaying progression in advanced cases. The recommended dose remains 400mg once daily, with potential escalation to 600-800mg for resistant strains, as per oncology guidelines. It also finds application in dermatofibrosarcoma protuberans (DFSP), aggressive systemic mastocytosis, and certain myelodysplastic syndromes, broadening its utility in precision medicine.​\n\nHealthcare providers monitor response via PCR for BCR-ABL transcripts in CML or imaging for GIST, adjusting therapy based on milestones like major molecular response. Patients with Ph+ acute lymphoblastic leukemia (ALL) may receive it adjunctively, enhancing outcomes when combined with chemotherapy. Overall, IMATIFLOW 400 transforms these diseases from fatal to chronically manageable.​\n\nKey Benefits\nOne standout benefit of IMATIFLOW 400 is its oral convenience, eliminating the need for frequent hospital visits associated with infusions. Response rates exceed 90% in early CML, with many patients achieving treatment-free remission after sustained deep responses, a paradigm shift from interferon-era therapies.​\n\nTumor control in GIST prevents life-threatening complications like bowel obstruction, improving survival from months to years. Its specificity reduces severe toxicities, allowing patients to maintain daily activities, work, and social engagements with minimal disruption. Long-term studies report 10-year survival rates above 80% in CML, underscoring durable efficacy.​\n\nAdditional advantages include cost-effectiveness over biologics and compatibility with supportive care like hydroxyurea for cytoreduction. Fluid retention, while common, responds well to diuretics, preserving cardiac function. For Indian patients, accessible pricing via brands like IMATIFLOW 400 supports equitable care in resource-limited settings.​\n\nPotential Side Effects\nWhile generally well-tolerated, IMATIFLOW 400 can cause edema (swelling in legs or face) in up to 70% of users, managed by dose reduction or supportive measures. Gastrointestinal issues like nausea, vomiting, and diarrhea affect 40-50%, often resolving with antiemetics and dietary adjustments.​\n\nMusculoskeletal pain, cramps, and fatigue occur frequently, alongside rash and abdominal discomfort. Hematologic effects include neutropenia or thrombocytopenia, necessitating regular blood counts. Rare but serious risks involve liver enzyme elevation, heart failure, or hemorrhage; prompt reporting of symptoms like shortness of breath or yellowing skin is crucial.​\n\nAvoid grapefruit juice, as it elevates drug levels, and inform doctors of concurrent medications like CYP3A4 inhibitors. Pregnancy category D status advises contraception, with monitoring for growth retardation in exposed fetuses. Dizziness may impair driving, so caution is essential during initial weeks.​\n\nDosage and Administration Guidelines\nSwallow IMATIFLOW 400 whole with a meal and full glass of water to optimize pharmacokinetics and reduce esophageal irritation. The standard adult dose for CML chronic phase is 400mg daily; for accelerated phase or blast crisis, 600mg. GIST dosing mirrors 400mg, titrated based on tolerance and response.​\n\nRenal or hepatic impairment requires dose adjustments—reduce to 300-400mg in moderate cases. Do not crush or chew tablets. Missed doses should be taken promptly unless near the next, avoiding doubles. Long-term use demands quarterly monitoring of CBC, liver function, and ECG.​\n\nPrecautions and Interactions\nPatients with a cardiac history need baseline echocardiograms, as QT prolongation or effusion risks exist. Drug interactions abound: St. John's wort induces metabolism, reducing efficacy; ketoconazole boosts levels. Vaccines, especially live ones, are contraindicated during therapy.​\n\nRegular dermatologic checks mitigate skin cancer risk from prolonged use. Hydration combats fluid retention, and low-salt diets aid management. Steris Healthcare emphasizes patient education via counseling on adherence for optimal outcomes.​\n\nConclusion\nIMATIFLOW 400 (Imatinib IP 400mg) stands as a testament to targeted therapy's power, offering robust control over CML, GIST, and related cancers with a balance of efficacy and manageability. Its benefits in prolonging life and enhancing daily functioning far outweigh transient side effects for most when monitored diligently. Consult oncologists for personalized plans, ensuring this innovative treatment maximizes hope and health in the fight against cancer.", "price": 1827.0, "discountamount": 540.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2249, "imageuri": "https://productimages.withfloats.com/actual/6943b026ca1b0dcfc6c37820.png", "tileimageuri": "https://productimages.withfloats.com/tile/6943b026ca1b0dcfc6c37820.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-18T07:38:46.766Z", "updatedon": "2025-12-18T07:41:25.851Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/imatinib-ip-400mg/2249", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "IMATIFLOW 400", "category": "NEPHROLOGYRANGE", "tags": [ "Imatinib IP 400mg", "offering robust control over CML.", "related cancers with a balance of efficacy and manageability.", "innovative treatment maximizes hope and health in the fight against cancer.", "cancer therapy.", "fuel cancer cell growth.", "chemotherapy." ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69400227de5d3e57a9340a50", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Nebivolol and s-amlodipine Tablets 5/2.5 mg", "description": "NEBIVALVE AM is a combination tablet containing Nebivolol and S-Amlodipine, designed to provide effective management of hypertension (high blood pressure). Hypertension is a leading risk factor for cardiovascular diseases in India, including heart attacks, strokes, and kidney complications.\n\nThis dual-action formulation combines the benefits of Nebivolol, a cardio-selective beta-blocker, with S-Amlodipine, a calcium channel blocker, providing comprehensive blood pressure control. The combination helps relax blood vessels, improve blood flow, and reduce cardiac workload, offering a convenient and effective option for patients requiring combination therapy.\n\nUses\n\nNEBIVALVE AM is primarily prescribed for:\n\nEssential Hypertension\nLowers elevated blood pressure to reduce the risk of cardiovascular complications.\n\nCardiovascular Risk Reduction\nHelps in preventing heart attacks, strokes, and heart failure in high-risk patients.\n\nManagement of Stable Angina\nBy reducing cardiac workload and improving oxygen supply to the heart.\n\nCombination Therapy in Resistant Hypertension\nSuitable for patients who do not achieve target blood pressure with single-drug therapy.\n\nBenefits\n1. Dual Mechanism of Action\n\nNebivolol: Blocks beta-1 adrenergic receptors in the heart, reducing heart rate and cardiac output. It also promotes nitric oxide release, helping dilate blood vessels.\n\nS-Amlodipine: Relaxes vascular smooth muscles by blocking calcium channels, improving blood flow and reducing blood pressure.\n\n2. Effective Blood Pressure Control\n\nThe combination provides better blood pressure reduction compared to either drug alone, helping patients achieve their target levels faster.\n\n3. Cardiovascular Protection\n\nReduces strain on the heart, lowers risk of stroke, and supports overall heart health.\n\n4. Once-Daily Convenience\n\nThe tablet can be taken once daily, enhancing patient adherence to therapy.\n\n5. Well-Tolerated Formulation\n\nBoth Nebivolol and S-Amlodipine are generally well tolerated, minimizing side effects when used as prescribed.\n\nDosage\n\nTypical Dose: One tablet of NEBIVALVE AM once daily, preferably at the same time each day.\n\nAdministration: Swallow the tablet whole with water. Do not crush or chew.\n\nIndividualization: The dose may be adjusted by the physician based on blood pressure response and patient tolerability.\n\nLifestyle Measures: Continue dietary modifications, regular exercise, and salt restriction alongside medication for optimal results.\n\nImportant: Do not stop the medication abruptly without consulting your doctor, as sudden withdrawal may worsen blood pressure control or cardiac function.\n\nSide Effects\n\nNEBIVALVE AM is generally well tolerated, but some patients may experience mild side effects, including:\n\nDizziness or lightheadedness\n\nFatigue or weakness\n\nHeadache\n\nFlushing or swelling of ankles (edema)\n\nMild gastrointestinal discomfort\n\nRare but Serious Side Effects\n\nSlow heart rate (bradycardia)\n\nSevere hypotension (low blood pressure)\n\nWorsening of heart failure in susceptible patients\n\nAllergic reactions such as rash or swelling\n\nSeek immediate medical attention if severe symptoms such as fainting, chest pain, or shortness of breath occur.\n\nPrecautions and Warning\n\nPregnancy and Breastfeeding: Use only if clearly indicated and prescribed by a doctor.\n\nHeart Conditions: Inform your doctor if you have heart failure, arrhythmia, or recent heart attack.\n\nKidney or Liver Impairment: Dose adjustment may be necessary.\n\nDiabetes: Nebivolol may mask symptoms of low blood sugar; monitor blood glucose closely.\n\nDrug Interactions: Notify your doctor about all medications, especially other blood pressure drugs, anti-arrhythmics, or diuretics.\n\nAvoid Alcohol: Alcohol may increase the risk of hypotension or dizziness.\n\nRegular Monitoring: Blood pressure and heart rate should be monitored periodically during therapy.\n\nConclusion\n\nNEBIVALVE AM (Nebivolol and S-Amlodipine Tablets) is a safe and effective combination therapy for managing hypertension and reducing cardiovascular risks. By combining Nebivolol’s beta-blocking and vasodilatory effects with S-Amlodipine’s calcium channel blocking action, it provides superior blood pressure control and cardiovascular protection.", "price": 210.0, "discountamount": 63.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2246, "imageuri": "https://productimages.withfloats.com/actual/69400229d51eeda87e74dba0.png", "tileimageuri": "https://productimages.withfloats.com/tile/69400229d51eeda87e74dba0.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-15T12:42:15.327Z", "updatedon": "2025-12-16T05:52:43.351Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/nebivolol-and-s-amlodipine-tablets-5-2-5-mg/2246", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "NEBIVALVE AM", "category": "CARDIOLOGY", "tags": [ "nebivolol and s-amlodipine tablets", "nebivolol and s-amlodipine tablets uses", "nebivolol and s-amlodipine tablets uses in hindi", "nebivolol", "s-amlodipine tablets", "hypertension (high blood pressure)", "heart attacks", "strokes", "kidney complications", "blood pressure contro", "helps relax blood vessels", "improve blood flow" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "693c0a0eb7439f8802544bc8", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "RIBAVIRIN CAPSULES IP 100mg", "description": "REBATERIS 100 contains Ribavirin IP 100mg in a hard gelatin capsule filled with white to off-white powder for optimal stability and bioavailability. Each pack typically includes 30 capsules, designed for oral administration with food to enhance absorption and reduce gastrointestinal upset. Ribavirin, a synthetic guanosine nucleoside analog, interferes with viral RNA polymerase and mRNA capping, halting hepatitis C virus (HCV) replication at multiple stages. This broad-spectrum antiviral also shows activity against respiratory syncytial virus (RSV) in select pediatric cases, though its primary indication remains HCV genotype management.​\n\nThe 100mg strength allows for weight-based dosing adjustments, making REBATERIS 100 suitable for adults and children over 3 years under specialist supervision. Unlike higher 200mg capsules, it supports finer dose reductions during therapy to manage side effects, ensuring better tolerability. Stored at room temperature away from moisture, it maintains potency for extended shelf life, aligning with pharmacopeial standards for purity and dissolution.​\n\nKey Uses\nREBATERIS 100 treats chronic hepatitis C virus infection in combination therapies, particularly for patients ineligible for all-oral direct-acting antivirals. It boosts sustained virologic response rates when paired with pegylated interferon alfa, addressing genotypes 1 through 6 based on regional guidelines.​\n\nIn severe RSV lower respiratory tract infections, off-label use occurs in hospitalized infants, where aerosolized forms predominate, but oral REBATERIS 100 contributes to interferon combos for immunocompromised children. It curbs viral load, prevents liver fibrosis progression, and reduces cirrhosis risk, making it essential for long-term liver preservation.​\n\nAdditionally, emerging evidence supports its adjunct role in certain hemorrhagic fevers like Lassa virus, though availability limits widespread application. Always initiated by hepatologists, treatment durations span 24-48 weeks depending on genotype, viral load, and response milestones.​\n\nMajor Benefits\nREBATERIS 100 enhances viral clearance, achieving up to 50-80% sustained response rates in interferon combinations, significantly lowering hepatocellular carcinoma risk over five years. Patients experience normalized liver enzymes and fibrosis regression on biopsy follow-up.​\n\nIts oral capsule form simplifies adherence compared to injectables, with twice-daily dosing fitting daily routines. The 100mg potency permits precise titration—e.g., 800-1400mg daily divided—for personalized therapy, minimizing excess exposure in lighter patients.​\n\nLong-term, it preserves liver function, averting transplants and improving quality of life metrics like fatigue reduction and work productivity. Cost-effective for resource-limited settings, REBATERIS 100 bridges gaps until pan-genotypic regimens become accessible.​\nBenefit\tMechanism\tClinical Impact\nViral Suppression\tRNA polymerase inhibition ​\t>50% SVR in combos ​\nLiver Protection\tFibrosis halt ​\tReduced cirrhosis by 30-40%\nFlexible Dosing\t100mg increments ​\tBetter tolerability, adherence\nBroad Genotype Coverage\tMulti-genotype efficacy ​\tVersatile for diverse patients\nPotential Side Effects\nCommon side effects include hemolytic anemia, peaking at weeks 4-8, necessitating hemoglobin monitoring and dose cuts to 600mg daily if levels drop below 10g/dL. Fatigue, headache, and insomnia affect over 40% of users, often resolving post-therapy.​\n\nGastrointestinal issues like nausea, diarrhea, and anorexia occur in 20-30%, mitigated by food intake. Dermatologic reactions—rash, pruritus—or flu-like symptoms from interferon pairing demand vigilance. Teratogenicity risks are high; dual contraception is mandatory for 6 months post-treatment due to sperm/ovum mutagenicity.​\n\nSerious risks encompass pulmonary infiltrates, cardiac ischemia in vulnerable patients, and thyroid dysfunction. Avoid in hemoglobinopathies, severe renal impairment (CrCl <50mL/min), or pregnancy. Regular blood counts and ophthalmologic exams guide safe continuation.​\n\nDosage Guidelines\nDosing is weight-based: adults <75kg receive mg/day (10 capsules: 5 AM, 5 PM); ≥75kg get 1200 mg/day (12 capsules: 6 AM, 6 PM), swallowed whole with meals. Pediatrics (≥3 years): 15mg/kg/day divided BID, rounded to the nearest 100mg via REBATERIS 100 capsules.​\n\nReduce by 200-400mg for anemia or neutropenia; discontinue if unresolved. Duration: 48 weeks for genotype 1, 24 weeks for others, with viral load checks at week 12. Swallow intact; no crushing.​\nConclusion\nREBATERIS 100 empowers hepatitis C management with proven antiviral potency and dosing precision from Steris Healthcare. 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