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{ "products": [ { "_id": "691b17834c6b1fd261aeaae2", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Dothiepin 75mg and Methylcobalamin 1500mcg | DROTHEPINE M 75", "description": "DROTHEPINE M 75 is a clinically formulated combination that unites the therapeutic strength of Dothiepin 75mg, a tricyclic antidepressant, with Methylcobalamin 1500mcg, an essential neurovitamin known for its nerve-repairing properties. This high-strength formulation is designed to support individuals facing depression, anxiety, neuropathic pain, and nerve degeneration associated with vitamin B12 deficiency. Dothiepin works by restoring chemical balance in the brain to improve mood, sleep, and emotional well-being. Meanwhile, Methylcobalamin helps repair damaged nerves and enhances nerve conduction. Together, these components make DROTHEPINE M 75 a comprehensive solution for boosting both mental health and neurological function.\n\nUses\n\nDROTHEPINE M 75 is recommended for the treatment and management of several psychological and nerve-related conditions. Its primary uses include:\n\nTreatment of Major Depression and Anxiety Disorders: Helps reduce persistent sadness, irritability, and emotional instability.\n\nManagement of Neuropathic Pain: Effective for nerve pain caused by diabetes, injuries, and chronic nerve damage.\n\nCorrection of Vitamin B12 Deficiency: Supports proper nerve functioning in individuals with low B12 levels.\n\nRelief from Nerve Tingling, Burning, and Numbness: Ideal for managing peripheral neuropathy symptoms.\n\nSupport for Sleep Disturbances Linked to Stress or Depression: Promotes relaxation and improves sleep quality.\n\nThese multifaceted uses make DROTHEPINE M 75 a trusted choice for patients needing both emotional and neurological support.\n\nBenefits\n\nThe powerful combination of Dothiepin 75mg and Methylcobalamin 1500mcg delivers a wide range of therapeutic benefits:\n\n1. Enhanced Mood Regulation\n\nDothiepin helps restore the balance of neurotransmitters like serotonin and norepinephrine, providing relief from depression and anxiety while enhancing overall emotional stability.\n\n2. Supports Nerve Regeneration\n\nMethylcobalamin promotes nerve cell repair, improves nerve signaling, and helps reduce neuropathic pain more effectively than standard B12 forms.\n\n3. Dual Action for Mental and Nerve Health\n\nBy targeting both emotional and physical discomfort, DROTHEPINE M 75 offers holistic relief, making daily life more manageable.\n\n4. Improved Sleep and Cognitive Clarity\n\nThe antidepressant component reduces stress-related sleep disturbances and supports improved focus, concentration, and memory.\n\n5. Best-in-Class Strength for Long-Lasting Relief\n\nWith a higher 75mg dose of Dothiepin, this formulation provides sustained action throughout the day, delivering dependable symptom control.\n\nDosage\n\nThe typical recommended dosage of DROTHEPINE M 75 is one tablet once daily, or as directed by a healthcare professional.\n\nTake the tablet with water, preferably after meals to reduce gastrointestinal discomfort.\n\nDosage may differ based on individual needs, severity of symptoms, and medical history.\n\nConsistency is key—take the medication at the same time each day for optimal results.\n\nDo not increase, reduce, or stop the dosage abruptly without consulting a doctor.\n\nSide Effects\n\nAlthough DROTHEPINE M 75 is generally well-tolerated, some individuals may experience mild side effects, especially at the beginning of treatment. These may include:\n\nDrowsiness or dizziness\n\nDry mouth\n\nConstipation\n\nBlurred vision\n\nFatigue or tiredness\n\nIncreased appetite or weight changes\n\nMild nausea or headache\n\nSevere side effects are uncommon, but seek immediate medical attention if you experience irregular heartbeat, severe dizziness, allergic reactions, or sudden mood changes.\n\nPrecautions and Warning\n\nAvoid alcohol while taking this medication, as it may intensify drowsiness and impair alertness.\n\nNot recommended during pregnancy or breastfeeding unless prescribed by a healthcare provider.\n\nPeople with heart problems, glaucoma, epilepsy, liver disease, or urinary retention must inform their doctor before use.\n\nThis medicine may cause drowsiness—avoid driving or operating machinery until you know how it affects you.\n\nDo not discontinue the medicine abruptly; dosage reduction should be supervised by a doctor.\n\nKeep the medication stored in a cool, dry place away from children.\n\nConclusion\n\nDROTHEPINE M 75, formulated with Dothiepin 75mg and Methylcobalamin 1500mcg, is an advanced dual-action therapy designed to support emotional well-being and nerve health simultaneously. It effectively treats depression, anxiety, neuropathic pain, and vitamin B12 deficiency while promoting nerve repair and cognitive clarity. When taken under medical supervision, this powerful combination helps restore balance, reduce discomfort, and improve your overall quality of life.", "price": 360.0, "discountamount": 108.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2209, "imageuri": "https://productimages.withfloats.com/actual/691b1786743983a7e3b55dc4.png", "tileimageuri": "https://productimages.withfloats.com/tile/691b1786743983a7e3b55dc4.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-17T12:39:31.538Z", "updatedon": "2025-11-17T12:41:13.788Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/dothiepin-75mg-and-methylcobalamin-1500mcg-drothepine-m-75/2209", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Steris Healthcare Pvt. Ltd.", "category": "NEUROLOGY", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "67a35e1c4d6823e26538d21d", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Empagliflozin (12.5mg), Metformin Hydrochloride (500mg)", "description": "GLIEMPAFLOZIN MET 12.5mg/500mg is a powerful combination medication formulated to manage type 2 diabetes mellitus (T2DM) effectively. It contains Empagliflozin (12.5mg) and Metformin Hydrochloride (500mg), two potent anti-diabetic agents that work synergistically to regulate blood sugar levels. This medication helps in improving glycemic control while reducing the risk of diabetes-related complications. It is prescribed as an adjunct to diet and exercise to enhance blood glucose regulation in adults with type 2 diabetes.\n\n \nKey Benefits:\n \n\n Effective Blood Sugar Control: Helps in lowering HbA1c levels, leading to better long-term glucose management.\nPromotes Weight Loss: Empagliflozin assists in weight reduction by eliminating excess glucose through urination.\nReduces Cardiovascular Risk: Beneficial for patients with heart-related complications linked to diabetes.\nImproves Insulin Sensitivity: Metformin enhances insulin action, reducing insulin resistance.\nPrevents Kidney Damage: Helps in reducing the burden on kidneys by decreasing glucose reabsorption.\nConvenient Combination Therapy: Eliminates the need for multiple medications by combining two effective drugs in one tablet.\n \nHow Does It Work?\n \n\nGLIEMPAFLOZIN MET 12.5mg/500mg works through a dual mechanism:\n\nEmpagliflozin blocks SGLT2 in the kidneys, preventing glucose reabsorption and promoting its excretion through urine. This leads to a significant reduction in blood sugar levels.\n\nMetformin lowers hepatic glucose production, decreases intestinal glucose absorption, and enhances insulin sensitivity, ensuring better blood glucose utilization by the body.\n\n \nDirections for Use:\n \n\nTake one tablet daily or as directed by your healthcare provider.\n\nSwallow the tablet whole with a glass of water. Do not crush or chew it.\n\nIt is recommended to take the medication with food to minimize gastrointestinal side effects.\n\nFollow a balanced diet and regular exercise regimen for optimal results.\n\nMonitor blood sugar levels regularly to ensure proper dosage adjustments.\n\n \nSide Effects:\n \n\nAlthough GLIEMPAFLOZIN MET 12.5mg/500mg is well tolerated, some patients may experience mild to moderate side effects, including:\n\nFrequent Urination due to glucose excretion\n\nDehydration or thirst\n\nHypoglycemia (Low Blood Sugar) when used with other anti-diabetic medications\n\nGastrointestinal Issues such as nausea, diarrhea, or stomach discomfort\n\nUrinary Tract Infections (UTIs) due to increased glucose in urine\n\nLactic Acidosis (Rare but Serious) in some cases due to Metformin", "price": 155.0, "discountamount": 47.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": [ "tablet daily", "balanced diet", "medication helps", "nausea diarrhea", "experience mild", "body directions", "significant reduction", "effective drugs", "multiple medications", "weight reduction", "work synergistically", "empagliflozin 125mg", "cases due", "diabetesrelated complications", "increased glucose", "glucose excretion dehydration", "regular exercise regimen", "metformin hydrochloride 500mg", "frequent urination due", "heartrelated complications linked", "blood glucose utilization", "eliminating excess glucose", "moderate side effects", "gliempaflozin met 125mg500mg", "healthcare provider swallow", "improving glycemic control", "potent antidiabetic agents" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2050, "imageuri": "https://productimages.withfloats.com/actual/67a35e57b167fbeb7927d316.png", "tileimageuri": "https://productimages.withfloats.com/tile/67a35e57b167fbeb7927d316.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-02-05T12:48:28.684Z", "updatedon": "2025-03-17T11:04:23.276Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/empagliflozin-12-5mg-metformin-hydrochloride-500mg-/2050", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "GLIEMPAFLOZIN MET 12.5mg/ 500mg", "category": "DIABETIC RANGE", "tags": [ "empagliflozin 12.5 mg+metformin 500 mg", "empagliflozin/metformin 5 mg/1000 mg", "Empagliflozin 12.5 mg brands in India", "empagliflozin 12.5 mg+metformin 500 mg price" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "66fd3dbc096a50a033e5b387", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Silodosin (8mg), Dutasteride (0.5mg)", "description": "SILODOSOLID 8D is a combination medication designed to effectively manage symptoms of benign prostatic hyperplasia (BPH), commonly known as an enlarged prostate. This powerful formula contains Silodosin (8mg) and Dutasteride (0.5mg), working together to provide relief from urinary difficulties and improve quality of life for men suffering from prostate enlargement.\n\n \n\nKey Ingredients:\n \n\nSilodosin (8mg): Silodosin is an alpha-blocker that relaxes the muscles in the prostate and bladder, making it easier to pass urine and relieving symptoms of BPH.\nDutasteride (0.5mg): Dutasteride belongs to a class of medications called 5-alpha-reductase inhibitors. It helps shrink the enlarged prostate by reducing the production of dihydrotestosterone (DHT), a hormone that contributes to prostate growth.\n \n\nKey Benefits:\n \n\nRelieves symptoms of BPH, including difficulty in urination, frequent urination, and a weak urine stream.\nHelps shrink the prostate gland, improving urine flow and reducing the need for surgery.\nReduces the risk of urinary retention and other complications related to BPH.\nProvides long-term management of prostate enlargement symptoms.\n \n\nHow Does It Work?\n \nSILODOSOLID 8D works by combining the effects of Silodosin and Dutasteride. Silodosin acts as an alpha-blocker, relaxing the muscles around the prostate and bladder neck to ease the flow of urine. Dutasteride, on the other hand, targets the hormone DHT, which is responsible for prostate enlargement. By lowering DHT levels, Dutasteride reduces prostate size, leading to improved urinary function and a reduction in BPH symptoms.\n\n \n\nDirections for Use:\n \n\nTake SILODOSOLID 8D exactly as prescribed by your healthcare provider. Typically, one capsule is taken once a day, with or without food. Swallow the capsule whole without chewing or crushing it. For best results, follow the prescribed dosage schedule and avoid missing doses.\n\n \n\nSide Effects:\n \n\nWhile SILODOSOLID 8D is effective for many, it may cause some side effects, including:\n\nDizziness or lightheadedness\nEjaculation problems or reduced sexual desire\nBreast tenderness or enlargement\nHeadache\nDiarrhea\nNasal congestion", "price": 339.0, "discountamount": 101.7, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "urine flow", "DHT levels", "other hand", "one capsule", "BPH symptoms", "bladder neck", "Side Effects", "best results", "Key Benefits", "prostate size", "sexual desire", "missing doses", "prostate gland", "SILODOSOLID 8D", "prostate growth", "dosage schedule", "Key Ingredients", "Nasal congestion", "urinary function", "powerful formula", "enlarged prostate", "Breast tenderness", "urinary retention", "weak urine stream", "frequent urination", "healthcare provider", "other complications", "Ejaculation problems", "long-term management", "urinary difficulties", "combination medication", "benign prostatic hyperplasia", "prostate enlargement symptoms" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1984, "imageuri": "https://productimages.withfloats.com/actual/66fd3dc44f132d08f7e5354f.png", "tileimageuri": "https://productimages.withfloats.com/tile/66fd3dc44f132d08f7e5354f.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-10-02T12:34:04.798Z", "updatedon": "2024-10-02T12:34:04.798Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/silodosin-8mg-dutasteride-0-5mg-/1984", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "SILODOSOLID 8D ", "category": "UROLOGYRANGE", "tags": [ "Silodosin 8D Capsule", "Silodosin 8d Uses in Hindi", "Difference between Silodal and Silodal D" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "66d84378023454f4a668f11f", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Chondroitin Sulfate Sodium 200mg, Collagen Peptides Type 40mg, Sodium Hyaluronate 30mg, Vitamin C 12.5mg", "description": "ACTOTEND \nChondroitin Sulfate Sodium 200mg, Collagen Peptides Type 40mg, Sodium Hyaluronate 30mg, Vitamin C 12.5mg\nACTOTEND is a dietary supplement formulated to support joint health and mobility. Combining the benefits of Chondroitin Sulfate Sodium, Collagen Peptides, Sodium Hyaluronate, and Vitamin C, ACTOTEND is designed to enhance joint function, reduce discomfort, and promote overall joint wellness. Whether you are experiencing joint issues due to aging, physical activity, or other factors, ACTOTEND provides a comprehensive approach to maintaining healthy joints.\n\n \n\nKey Benefits:\n \n\nJoint Health Support: ACTOTEND helps in maintaining the health and integrity of cartilage, ensuring better joint function and mobility.\nPain Relief: By supporting cartilage and synovial fluid health, ACTOTEND can help reduce joint discomfort and pain associated with wear and tear.\nEnhanced Mobility: The combination of ingredients works synergistically to improve joint flexibility and ease of movement.\nCartilage Regeneration: With essential nutrients for cartilage synthesis and repair, ACTOTEND aids in the regeneration of joint tissues.\nAntioxidant Protection: Vitamin C provides antioxidant protection, reducing oxidative stress on joints and supporting overall joint health.\n \nHow Does It Work?\n \n\nACTOTEND works by delivering a potent blend of ingredients that target various aspects of joint health. Chondroitin Sulfate and Collagen Peptides provide the building blocks for cartilage, promoting its maintenance and repair. Sodium Hyaluronate enhances the lubrication of joints, reducing friction and wear during movement. Vitamin C supports collagen production and provides antioxidant protection, ensuring the overall health and resilience of joint tissues. Together, these ingredients help to alleviate joint pain, improve mobility, and support long-term joint health.\n\n \nDirections for Use:\n \n\nTake one ACTOTEND tablet daily with a glass of water, preferably after a meal. Consistent use is recommended for optimal results. Always follow the dosage instructions provided by your healthcare provider.\n\n \nSide Effects:\n \n\nACTOTEND is generally well-tolerated when taken as directed. However, some individuals may experience mild side effects, such as:\n\nGastrointestinal Discomfort: Minor stomach upset or nausea.\nAllergic Reactions: Rarely, some individuals may experience allergic reactions. Discontinue use and seek medical attention if you experience symptoms such as rash, itching, or swelling.\n For further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order NOW\n", "price": 415.0, "discountamount": 125.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "Vitamin C", "joint pain", "Pain Relief", "Key Benefits", "potent blend", "joint issues", "other factors", "joint tissues", "Consistent use", "healthy joints", "joint function", "overall health", "optimal results", "building blocks", "various aspects", "joint discomfort", "oxidative stress", "Enhanced Mobility", "medical attention", "physical activity", "joint flexibility", "mild side effects", "Allergic Reactions", "dietary supplement", "Sodium Hyaluronate", "cartilage synthesis", "healthcare provider", "dosage instructions", "essential nutrients", "collagen production", "one ACTOTEND tablet", "Minor stomach upset", "overall joint health", "Joint Health Support", "synovial fluid health", "Cartilage Regeneration", "Antioxidant Protection", "comprehensive approach", "long-term joint health", "Collagen Peptides Type", "overall joint wellness", "Chondroitin Sulfate Sodium", "Gastrointestinal Discomfort" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1964, "imageuri": "https://productimages.withfloats.com/actual/66d8437bce173d87109b5bca.jpeg", "tileimageuri": "https://productimages.withfloats.com/tile/66d8437bce173d87109b5bca.jpeg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-09-04T11:24:40.528Z", "updatedon": "2024-09-04T11:24:40.528Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/chondroitin-sulfate-sodium-200mg-collagen-peptides-type-40mg-sodium-hyaluronate-30mg-vitamin-c-12-5mg/1964", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "ACTOTEND ", "category": "ORTHOPEDICSRANGE", "tags": null, "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6662ada77247ae19c482b06f", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "TACRENOLIME 0.50", "description": "TACRENOLIME 0.50\nTacrolimus Capsules (0.5mg)\nTacrenolime 0.50 is a medication that comes in the form of Tacrolimus Capsules, with each capsule containing 0.5mg of Tacrolimus. Tacrolimus is an immunosuppressant drug that is commonly used to prevent rejection after organ transplantation. It works by suppressing the immune system's response to foreign substances, thereby reducing the risk of the body rejecting a transplanted organ.\n\nTacrolimus capsules are typically prescribed as part of a comprehensive transplant treatment regimen. The dosage and frequency of administration are determined by your healthcare provider based on factors such as your medical condition, response to treatment, and other medications you may be taking.\n\nIt's important to follow your doctor's instructions carefully when taking Tacrenolime 0.50. Do not adjust the dosage or stop taking the medication without consulting your healthcare provider. Missing doses or discontinuing treatment abruptly can increase the risk of transplant rejection or other complications.\n\nCommon side effects of Tacrenolime 0.50 may include nausea, vomiting, diarrhea, headache, dizziness, and changes in kidney function. Inform your doctor if you experience any persistent or severe side effects while taking this medication.\n\nTacrenolime 0.50 is an essential part of post-transplant care, helping to ensure the success of the transplant and improve long-term outcomes. Always keep your healthcare provider informed about any changes in your health or medications while using Tacrenolime 0.50.For further information:\nEmail: info@sterispharma.com / contact@sterispharma.com\nCall/WhatsApp: 7877551268, 7849827488\nOrder Now: \n\nhttps://www.sterisonline.com/product/tacrenolime-0-50-133685", "price": 224.0, "discountamount": 68.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "body", "Call", "form", "risk", "Order", "0.5mg", "Email", "dosage", "doctor", "nausea", "success", "changes", "factors", "vomiting", "diarrhea", "headache", "WhatsApp", "response", "frequency", "dizziness", "persistent", "TACRENOLIME", "sterispharma", "instructions", "sterisonline", "Missing doses", "immune system", "administration", "essential part", "kidney function", "medical condition", "other medications", "long-term outcomes", "foreign substances", "other complications", "Tacrolimus Capsules", "healthcare provider", "severe side effects", "Common side effects", "transplant rejection", "post-transplant care", "organ transplantation", "immunosuppressant drug", "comprehensive transplant treatment regimen" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1495, "imageuri": "https://productimages.withfloats.com/actual/6662ada8637f8700d7caf813.jpg", "tileimageuri": "https://productimages.withfloats.com/tile/6662ada8637f8700d7caf813.jpg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-07T06:50:15.551Z", "updatedon": "2024-06-28T11:42:30.421Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/tacrenolime-0-50/1495", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "TACRENOLIME 0.50", "category": "NEPHROLOGYRANGE", "tags": [ "TACRENOLIME 0.50", "Tacrolimus Capsules (0.5mg)", "tacrolimus 0.5 mg capsule price", "tacrolimus 1 mg capsule uses", "what is tacrolimus capsules used for" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "691b190c54131a1a1c761716", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Dothiepin 50mg and Methylcobalamin 1500mcg | DROTHEPINE M 50", "description": "DROTHEPINE M 50 is a specialized combination medicine that blends the antidepressant properties of Dothiepin 50mg with the nerve-repairing benefits of Methylcobalamin 1500mcg. This balanced formulation is designed to support individuals dealing with depression, anxiety, neuropathic pain, and vitamin B12 deficiency–related nerve issues. Dothiepin, a tricyclic antidepressant, helps restore neurotransmitter balance in the brain, promoting emotional stability and mental clarity. Methylcobalamin, an active form of vitamin B12, plays an essential role in nerve regeneration and optimal neurological functioning. Together, these two powerful ingredients make DROTHEPINE M 50 an effective choice for improving mood, reducing nerve discomfort, and enhancing overall quality of life.\n\nUses\n\nDROTHEPINE M 50 is commonly prescribed for a wide range of mental and neurological conditions. Its primary uses include:\n\nTreatment of Depression and Anxiety: Helps relieve persistent low mood, tension, nervousness, and emotional imbalance.\n\nManagement of Neuropathic Pain: Effective for nerve pain caused by diabetes, nerve injuries, and chronic nerve degeneration.\n\nCorrection of Vitamin B12 Deficiency: Supports nerve health and improves symptoms associated with B12 deficiency.\n\nRelief from Tingling, Burning, and Numbness: Suitable for individuals experiencing peripheral neuropathy symptoms.\n\nImproves Sleep Patterns: Beneficial for individuals suffering from insomnia or disturbed sleep linked to depression or mental stress.\n\nBenefits\n\nThe combination of Dothiepin 50mg and Methylcobalamin 1500mcg offers several key therapeutic benefits:\n\n1. Balanced Mood Enhancement\n\nDothiepin works by regulating serotonin and norepinephrine levels in the brain, helping alleviate depressive symptoms, anxiety, and emotional trauma.\n\n2. Supports Nerve Repair and Regeneration\n\nMethylcobalamin aids in repairing damaged nerve cells, enhancing nerve signal transmission, and reducing nerve-related discomfort.\n\n3. Comprehensive Relief for Mental and Nerve Conditions\n\nBy addressing both mental health concerns and nerve pain, DROTHEPINE M 50 offers a dual-action therapeutic approach.\n\n4. Enhances Cognitive Performance\n\nImproved neurotransmitter balance and nerve function contribute to better concentration, memory, and overall mental clarity.\n\n5. Helps Improve Daily Functionality\n\nWith reduced pain, improved mood, and better sleep quality, patients can experience enhanced productivity and a better quality of life.\n\nDosage\n\nThe typical recommended dosage for DROTHEPINE M 50 is one tablet per day, or as directed by a healthcare provider.\n\nTablets should be taken with water, preferably after a meal to support absorption and reduce stomach upset.\n\nDosage may vary depending on the individual’s medical history, condition severity, and treatment response.\n\nConsistent daily use is essential for achieving long-term benefits.\n\nDo not change the dosage or stop the medication abruptly without consulting a doctor.\n\nSide Effects\n\nLike all medications, DROTHEPINE M 50 may cause some side effects, although not everyone experiences them. Common side effects may include:\n\nDrowsiness or dizziness\n\nDry mouth\n\nConstipation\n\nBlurred vision\n\nIncreased appetite or slight weight gain\n\nMild nausea\n\nFatigue or weakness\n\nOccasional headaches\n\nSevere side effects are rare, but if you experience rapid heartbeat, severe dizziness, allergic reactions, or mood changes, seek medical attention immediately.\n\nPrecautions and Warning\n\nAvoid alcohol use during treatment, as it may increase drowsiness and impair judgment.\n\nNot advisable during pregnancy or breastfeeding unless recommended by a healthcare professional.\n\nIndividuals with heart disease, glaucoma, epilepsy, or liver problems should inform their doctor before starting this medication.\n\nThis medicine may cause drowsiness—avoid driving or operating machinery until its effects are known.\n\nDo not discontinue the medication suddenly; dosage adjustments must be done under medical supervision.\n\nStore the product in a cool, dry place and keep it out of reach of children.\n\nConclusion\n\nDROTHEPINE M 50, a powerful combination of Dothiepin 50mg and Methylcobalamin 1500mcg, provides an effective and balanced solution for managing depression, anxiety, neuropathic pain, and vitamin B12 deficiency. Its dual-action formula supports mental health while promoting nerve repair, improving cognitive performance, and offering long-lasting relief from discomfort. When taken under medical guidance, DROTHEPINE M 50 can help restore emotional stability, reduce nerve symptoms, and significantly enhance overall well-being.", "price": 270.0, "discountamount": 81.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2210, "imageuri": "https://productimages.withfloats.com/actual/691b190e7361b0a74ff6bb95.png", "tileimageuri": "https://productimages.withfloats.com/tile/691b190e7361b0a74ff6bb95.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-17T12:46:04.063Z", "updatedon": "2025-11-17T12:46:04.063Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/dothiepin-50mg-and-methylcobalamin-1500mcg-drothepine-m-50/2210", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Steris Healthcare Pvt Ltd", "category": "NEUROLOGY", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69143c14e91a8f3f57dea824", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Rifaximin oral suspension 100mg/5ml", "description": "Rifaximin Oral Suspension 100 mg/5 ml is a broad-spectrum, gut-selective antibiotic formulated to treat various bacterial infections of the gastrointestinal tract, including traveler’s diarrhea, hepatic encephalopathy-related symptoms, and irritable bowel syndrome with diarrhea (IBS-D). Its unique non-systemic activity ensures that the drug acts locally in the intestines without significant absorption into the bloodstream, making it both effective and safe for long-term gastrointestinal management.\n\nDesigned in a pleasant-tasting, easy-to-administer oral suspension form, Rifaximin 100 mg/5 ml is especially suitable for pediatric patients and adults who have difficulty swallowing tablets. It is ideal for treating infections caused by non-invasive strains of Escherichia coli and other enteric bacteria, while also helping maintain intestinal balance and promoting recovery from gut-related complications.\n\nComposition\n\nEach 5 ml of suspension contains:\n\nRifaximin IP – 100 mg\n\nFlavored base and excipients – q.s.\n\nDosage Form: Oral Suspension\nAppearance: Pink to reddish suspension (depending on brand formulation)\nPackaging: Available in 30 ml, 60 ml, or 100 ml bottles with a measuring cup for accurate dosing.\n\nPharmacological Action and Mechanism\n\nRifaximin belongs to the rifamycin class of antibiotics and is structurally related to rifampicin. However, it has been specially modified to act locally in the gastrointestinal tract with negligible systemic absorption (<0.4%).\n\nMechanism of Action:\n\nRifaximin inhibits bacterial RNA synthesis by binding to the β-subunit of the bacterial DNA-dependent RNA polymerase.\n\nThis action prevents the transcription process, thereby stopping bacterial growth and replication.\n\nIts broad-spectrum activity covers both gram-positive and gram-negative bacteria, including aerobic and anaerobic strains.\n\nDue to poor absorption, it remains in the intestine at high concentrations, providing localized antibacterial effect without systemic toxicity.\n\nAdditionally, Rifaximin exerts eubiotic effects — it helps restore normal intestinal flora balance by selectively targeting harmful bacteria, which makes it useful for chronic intestinal disorders.\n\nUses and Indications\n\nRifaximin Oral Suspension 100 mg/5 ml is indicated for the following conditions:\n\nTraveler’s Diarrhea (TD):\n\nCaused by non-invasive strains of Escherichia coli.\n\nHelps relieve symptoms like watery stools, abdominal cramps, and bloating within a short duration.\n\nHepatic Encephalopathy (HE):\n\nUsed as adjunct therapy to reduce ammonia-producing gut bacteria, thereby lowering blood ammonia levels and improving mental status in patients with chronic liver disease.\n\nIrritable Bowel Syndrome with Diarrhea (IBS-D):\n\nProvides relief from abdominal pain, bloating, and irregular bowel movements by reducing bacterial overgrowth in the small intestine (SIBO).\n\nSmall Intestinal Bacterial Overgrowth (SIBO):\n\nHelps normalize gut flora and reduces gas, bloating, and discomfort caused by bacterial overgrowth.\n\nGastrointestinal Infections in Children:\n\nEffective in pediatric patients suffering from infectious diarrhea due to bacterial contamination of food or water.\n\nProphylactic Use:\n\nMay be prescribed post-surgery or in chronic liver disease to prevent recurrence of infection-related complications.\n\nDosage and Administration\n\nAdults and Children (>12 years): Usual dose is 10–20 ml (200–400 mg) every 8–12 hours, depending on the indication and physician’s recommendation.\n\nChildren (2–12 years): 5–10 ml (100–200 mg) two or three times daily, as directed by a pediatrician.\n\nShake the bottle well before each use.\n\nComplete the prescribed course even if symptoms improve early to prevent recurrence and antibiotic resistance.\n\nKey Benefits\n\nGut-Selective Action:\nActs locally within the intestine without entering systemic circulation, ensuring targeted therapy with minimal side effects.\n\nBroad-Spectrum Antibacterial Activity:\nEffective against a wide range of gram-positive, gram-negative, aerobic, and anaerobic enteric pathogens.\n\nSafe for Pediatric and Adult Use:\nThe liquid form allows accurate dosing and ease of administration, especially for children or elderly patients.\n\nMinimal Systemic Absorption:\nReduces the risk of systemic toxicity and drug interactions compared to conventional antibiotics.\n\nEffective for Traveler’s Diarrhea:\nRapidly controls diarrhea symptoms caused by E. coli and restores normal intestinal function.\n\nImproves Liver Health in Hepatic Encephalopathy:\nDecreases ammonia-producing bacteria, thereby reducing confusion, lethargy, and other symptoms related to hepatic encephalopathy.\n\nRestores Gut Microbiota Balance:\nHelps maintain healthy intestinal flora, supporting digestion and preventing recurrent infections.\n\nReduces Bloating and Abdominal Discomfort in IBS-D:\nProvides symptomatic relief and enhances quality of life in patients suffering from chronic bowel irregularities.\n\nLow Risk of Resistance:\nDue to its minimal absorption and targeted mechanism, the development of bacterial resistance is significantly lower.\n\nWell-Tolerated Formulation:\nThe oral suspension is gentle on the stomach and has a pleasant taste, improving compliance in children and adults alike.\n\nPrecautions and Warnings\n\nWhile Rifaximin Oral Suspension is considered safe for most patients, the following precautions should be observed:\n\nAllergy: Avoid use in patients with known hypersensitivity to rifaximin, rifampicin, or other rifamycin derivatives.\n\nSevere Diarrhea or Bloody Stool: If symptoms worsen or persist beyond 48 hours, consult a physician; may indicate an invasive infection requiring alternative therapy.\n\nLiver Impairment: Use with caution in patients with severe hepatic impairment; dosage adjustments may be required.\n\nPregnancy and Lactation: Limited data available; should be used only if clearly needed and prescribed by a doctor.\n\nLong-Term Use: Prolonged or unnecessary use may lead to superinfection by non-susceptible organisms, including fungi.\n\nDriving and Machinery: Generally safe, but dizziness or fatigue may occur in rare cases.\n\nPossible Side Effects\n\nRifaximin is generally well-tolerated due to its localized action in the gut. However, some mild to moderate side effects may occur in sensitive individuals.\n\nCommon Side Effects:\n\nNausea\n\nFlatulence (gas)\n\nAbdominal pain or cramping\n\nHeadache\n\nBloating\n\nConstipation\n\nLess Common / Rare Side Effects:\n\nSkin rash or itching\n\nDizziness or fatigue\n\nElevated liver enzymes (rare)\n\nVomiting or dry mouth\n\nFever or flu-like symptoms\n\nSerious Side Effects (Very Rare):\n\nAllergic reaction (rash, swelling, or breathing difficulty)\n\nPersistent watery or bloody diarrhea\n\nSevere abdominal pain\n\nIf any severe adverse reactions occur, discontinue use and seek medical attention immediately.\n\nStorage and Handling\n\nStore below 30°C in a cool, dry place.\n\nProtect from direct sunlight and freezing.\n\nShake well before use.\n\nKeep out of reach of children.\n\nDiscard any unused portion after the treatment course or expiry date.\n\nConclusion\n\nRifaximin Oral Suspension 100 mg/5 ml is a clinically trusted and patient-friendly antibiotic formulation for the treatment of gastrointestinal infections and liver-related complications. Its unique non-systemic mode of action, combined with broad antibacterial efficacy, makes it an excellent choice for both acute and chronic intestinal disorders.\n\nUnlike traditional antibiotics that circulate systemically, Rifaximin works locally within the intestines to eliminate harmful bacteria while preserving the natural gut flora. This results in faster relief from symptoms like diarrhea, bloating, and abdominal discomfort — with minimal side effects.\n\nWhether used for traveler’s diarrhea, hepatic encephalopathy, IBS-D, or bacterial overgrowth syndromes, Rifaximin offers targeted, safe, and effective therapy for restoring digestive health and improving overall well-being.", "price": 170.0, "discountamount": 51.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2204, "imageuri": "https://productimages.withfloats.com/actual/69143c160712d1e28ab8336e.png", "tileimageuri": "https://productimages.withfloats.com/tile/69143c160712d1e28ab8336e.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-12T07:49:40.243Z", "updatedon": "2025-11-12T07:49:40.243Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/rifaximin-oral-suspension-100mg-5ml/2204", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Steris Healthcare Pvt Ltd", "category": "Pediatric", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "691437f0df62fb2c61ddbc40", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Ginkgo Biloba Extract and Piracetam Tablets ", "description": "Ginkgo Biloba Extract & Piracetam Tablets is a scientifically formulated neuroprotective and cognitive-enhancing combination designed to support memory, concentration, and brain function. It combines two powerful agents — Ginkgo Biloba, a time-tested herbal extract known for its circulation-enhancing and antioxidant properties, and Piracetam, a well-researched nootropic compound that enhances neuronal communication and cognitive performance.\n\nTogether, these two active ingredients work synergistically to improve cerebral blood flow, increase oxygen and nutrient delivery to the brain, and enhance mental clarity and alertness. The formulation is widely prescribed as a neurotonic and cognitive enhancer for individuals experiencing memory decline, age-related cognitive impairment, or neurological disorders such as dementia, Alzheimer’s disease, and cerebrovascular insufficiency.\n\nComposition\n\nEach film-coated tablet typically contains:\n\nGinkgo Biloba Extract (Standardized to contain 24% Flavone Glycosides & 6% Terpene Lactones) – 40 mg or 60 mg\n\nPiracetam – 800 mg\n\nExcipients – q.s.\n\nThe tablets are designed for oral administration, offering convenient dosage and high bioavailability.\n\nMechanism of Action\n1. Ginkgo Biloba Extract\n\nGinkgo Biloba, derived from the leaves of the ancient Ginkgo tree, is rich in flavonoids and terpenoids, which possess antioxidant, vasodilatory, and neuroprotective properties. It acts through several mechanisms:\n\nImproves microcirculation: Enhances blood flow to brain tissues by reducing blood viscosity and promoting vasodilation.\n\nAntioxidant action: Neutralizes free radicals that cause oxidative stress, protecting neurons from damage.\n\nIncreases neurotransmitter activity: Supports the release and uptake of acetylcholine and serotonin, improving mood and memory.\n\nReduces platelet aggregation: Improves oxygen supply to the brain and minimizes risk of ischemic injury.\n\n2. Piracetam\n\nPiracetam is a nootropic (cognitive enhancer) that improves neuronal efficiency and communication between brain cells.\nIts mechanism includes:\n\nEnhancing neuronal plasticity: Facilitates the transmission of impulses across synapses, improving learning and memory.\n\nImproving cerebral blood flow and metabolism: Enhances glucose utilization and oxygen consumption in the brain.\n\nProtecting neurons: Increases membrane fluidity and stabilizes nerve cells against hypoxic or oxidative damage.\n\nTogether, Ginkgo Biloba and Piracetam complement each other to enhance mental performance, protect neural structures, and improve cerebral function.\n\nUses and Indications\n\nGinkgo Biloba Extract & Piracetam Tablets are indicated for the following conditions:\n\nCognitive Decline and Memory Disorders:\n\nImproves memory, focus, and concentration in elderly individuals or those with mild cognitive impairment.\n\nDementia and Alzheimer’s Disease:\n\nUsed as supportive therapy to slow progression of degenerative brain disorders and enhance daily functioning.\n\nCerebrovascular Insufficiency:\n\nBeneficial in cases of reduced blood flow to the brain, helping alleviate symptoms like dizziness, headache, and mental fatigue.\n\nPost-Stroke Rehabilitation:\n\nEnhances neurological recovery and helps restore cognitive function after ischemic brain injury.\n\nVertigo and Tinnitus (Ringing in the Ears):\n\nImproves inner ear circulation, reducing dizziness and balance-related issues.\n\nLearning Disorders and Attention Deficits:\n\nImproves attention span and memory recall in both adults and children.\n\nNeuroprotective Supplement for Elderly:\n\nMaintains brain vitality and helps prevent age-related cognitive decline.\n\nKey Benefits\n\nEnhances Memory and Concentration:\nThe synergistic effect of Ginkgo Biloba and Piracetam improves synaptic transmission and neuroplasticity, enhancing learning, focus, and recall.\n\nBoosts Cerebral Circulation:\nGinkgo Biloba improves microcirculation within brain tissues, ensuring efficient delivery of oxygen and glucose to neurons.\n\nProtects Against Neurodegeneration:\nThe powerful antioxidant activity of flavonoids and terpenes from Ginkgo Biloba helps neutralize harmful free radicals, delaying age-related brain cell damage.\n\nImproves Cognitive Function in Dementia:\nClinical studies have shown improved cognition, mood, and behavior in patients with Alzheimer’s and vascular dementia with this combination.\n\nRestores Energy and Mental Clarity:\nPiracetam enhances brain metabolism and ATP synthesis, combating mental fatigue and promoting alertness.\n\nAids Recovery After Stroke or Brain Injury:\nEnhances neural regeneration, oxygen utilization, and cerebral function in post-stroke rehabilitation.\n\nReduces Dizziness, Vertigo, and Tinnitus:\nGinkgo’s vasodilatory and anti-platelet properties improve blood flow to the inner ear and brain, alleviating these symptoms.\n\nSafe and Well-Tolerated:\nNon-sedating, non-addictive, and suitable for long-term use under medical supervision.\n\nDosage and Administration\n\nAdults: One tablet two or three times daily, or as directed by a physician.\n\nElderly Patients: Dosage may be adjusted according to tolerance and medical condition.\n\nChildren: Use only if prescribed by a doctor.\n\nTablets should be swallowed whole with water, preferably after meals to avoid gastrointestinal discomfort.\n\nPrecautions and Warnings\n\nMedical Supervision Required: Should only be used under the guidance of a healthcare professional, especially for elderly patients or those on multiple medications.\n\nBleeding Disorders: Ginkgo Biloba may increase bleeding risk; avoid in patients with clotting disorders or those taking anticoagulants.\n\nSurgery: Discontinue use at least two weeks before scheduled surgery to minimize bleeding risk.\n\nEpilepsy: Piracetam may lower the seizure threshold; caution advised in epileptic patients.\n\nPregnancy and Lactation: Safety not well established; use only if prescribed by a doctor.\n\nDriving or Operating Machinery: Some individuals may experience dizziness or drowsiness; caution advised.\n\nPossible Side Effects\n\nWhile generally safe, Ginkgo Biloba Extract & Piracetam Tablets may cause mild, transient side effects in some users. These typically resolve upon dosage adjustment or discontinuation.\n\nCommon Side Effects:\n\nHeadache or mild dizziness\n\nNausea or stomach discomfort\n\nNervousness or restlessness\n\nInsomnia (if taken late in the day)\n\nLess Common Side Effects:\n\nAllergic skin rash or itching\n\nGastrointestinal upset\n\nPalpitations or rapid heartbeat\n\nMild bleeding (nosebleed, bruising) in sensitive individuals\n\nTremors (rare, usually at higher doses)\n\nSeek medical help immediately if severe allergic reactions, confusion, or unusual bleeding occur.\n\nDrug Interactions\n\nAnticoagulants and Antiplatelet Agents (e.g., Warfarin, Aspirin): May increase bleeding risk.\n\nNSAIDs (e.g., Ibuprofen): Combined use may enhance bleeding tendency.\n\nAntiepileptic Medications: Use with caution as Piracetam may affect seizure control.\n\nHerbal Supplements (e.g., Garlic, Ginseng): May potentiate anticoagulant effects.\n\nStorage and Handling\n\nStore below 30°C, protected from moisture and direct sunlight.\n\nKeep out of reach of children.\n\nDo not use tablets past the expiry date or if the blister pack is damaged.\n\nConclusion\n\nGinkgo Biloba Extract & Piracetam Tablets represent a powerful blend of herbal wisdom and modern neuroscience, formulated to promote optimal brain function and long-term cognitive health. By enhancing blood circulation to the brain, protecting neurons from oxidative damage, and improving neurotransmitter activity, this combination supports memory, focus, and mental agility across all age groups.\n\nIdeal for individuals suffering from age-related memory loss, stress-induced mental fatigue, or neurological disorders, this formulation provides comprehensive neuroprotection and cognitive enhancement in a safe, well-tolerated form.", "price": 250.0, "discountamount": 75.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2203, "imageuri": "https://productimages.withfloats.com/actual/691437f3b2490379b1b47e37.png", "tileimageuri": "https://productimages.withfloats.com/tile/691437f3b2490379b1b47e37.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-12T07:32:00.682Z", "updatedon": "2025-11-12T07:32:00.682Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/ginkgo-biloba-extract-and-piracetam-tablets-/2203", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Steris Healthcare Pvt Ltd", "category": "NEUROLOGY RANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69142bf71d499513a92e5772", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Nicorandil Tablets 5mg", "description": "Nicorandil Tablets 5 mg is a vasodilatory anti-anginal medication widely prescribed for the management and prevention of angina pectoris (chest pain) associated with coronary artery disease (CAD). Angina results from an imbalance between the heart’s oxygen demand and supply due to restricted blood flow in the coronary arteries. Nicorandil offers a dual mechanism of action — acting both as a nitrate-like vasodilator and a potassium channel opener, making it unique among anti-anginal agents.\n\nBy improving oxygen delivery to the myocardium and reducing cardiac workload, Nicorandil 5 mg Tablets provide effective relief from anginal pain and reduce the frequency and severity of ischemic episodes. It is also beneficial in preventing future attacks, improving exercise tolerance, and enhancing the overall quality of life in patients with chronic stable angina.\n\nComposition\n\nEach tablet contains:\n\nNicorandil IP – 5 mg\n\nExcipients – q.s.\n\nNicorandil tablets are available in film-coated form to ensure stability, easy swallowing, and optimal absorption. They are manufactured in compliance with Good Manufacturing Practices (GMP) standards to ensure safety, purity, and efficacy.\n\nPharmacological Action / Mechanism of Action\n\nNicorandil exhibits a dual mechanism that makes it distinct among anti-anginal drugs:\n\nNitrate-Like Effect:\nNicorandil acts as a nitric oxide (NO) donor. Nitric oxide activates guanylate cyclase, increasing cyclic GMP (cGMP) levels in vascular smooth muscle. This leads to relaxation of blood vessels, particularly veins and large arteries, thereby reducing preload and afterload on the heart. This nitrate-like activity lowers myocardial oxygen demand.\n\nPotassium Channel Opening Effect:\nNicorandil opens ATP-sensitive potassium (KATP) channels in vascular smooth muscle, resulting in arteriolar vasodilation. This increases coronary blood flow and improves oxygen supply to ischemic heart tissues.\n\nTogether, these effects reduce cardiac workload, enhance coronary perfusion, and prevent anginal pain by correcting the oxygen supply-demand mismatch in the heart muscle.\n\nUses and Indications\n\nNicorandil Tablets 5 mg are indicated for the treatment and prevention of angina pectoris in adults, particularly:\n\nChronic Stable Angina:\n\nHelps reduce the frequency and severity of chest pain associated with exertion or emotional stress.\n\nProphylaxis of Angina Attacks:\n\nUsed regularly to prevent anginal episodes, especially in patients with known coronary artery disease.\n\nAdjunct Therapy in Ischemic Heart Disease (IHD):\n\nCan be used alongside beta-blockers, calcium channel blockers, or antiplatelet drugs for enhanced symptom control and long-term protection.\n\nImprovement of Exercise Tolerance:\n\nReduces the likelihood of anginal pain during physical activity, enabling patients to perform daily tasks comfortably.\n\nIn some clinical cases, Nicorandil is also considered for post-myocardial infarction recovery, as it improves coronary perfusion, although this is at the discretion of a cardiologist.\n\nDosage and Administration\n\nRecommended Starting Dose: 5 mg to 10 mg twice daily.\n\nMaintenance Dose: May be increased gradually to 10–20 mg twice daily, depending on clinical response and tolerance.\n\nThe tablets should be swallowed whole with water, preferably at the same times each day.\n\nNicorandil should not be stopped abruptly; dosage tapering is recommended to avoid rebound angina.\n\nAlways follow the dosage instructions provided by the physician.\n\nKey Benefits\n\nDual Mechanism for Comprehensive Relief:\nCombines nitrate-like and potassium channel-opening properties for both arterial and venous dilation, providing superior protection against anginal attacks.\n\nImproves Coronary Blood Flow:\nDilates coronary arteries, increasing oxygen delivery to ischemic myocardial tissues.\n\nReduces Cardiac Workload:\nBy decreasing preload (venous return) and afterload (arterial resistance), Nicorandil minimizes the heart’s oxygen consumption.\n\nRapid Onset of Action:\nNicorandil acts within a short duration, offering quick relief from anginal discomfort.\n\nPrevents Future Angina Episodes:\nRegular use helps maintain steady control of chest pain, improving exercise capacity and quality of life.\n\nCompatible with Other Cardiac Medications:\nCan be safely used alongside antiplatelet agents, beta-blockers, ACE inhibitors, and statins as part of comprehensive cardiac care.\n\nFavorable Safety Profile:\nCompared to nitrates, Nicorandil carries a lower risk of tolerance development, making it suitable for long-term therapy.\n\nEnhances Myocardial Protection:\nNicorandil’s KATP channel activation provides additional cardioprotective effects by improving microvascular blood flow and limiting ischemic damage during stress.\n\nPrecautions and Warnings\n\nAlthough Nicorandil is generally well-tolerated, certain precautions are advised:\n\nHypotension:\nNicorandil may cause a drop in blood pressure due to vasodilation. Caution is advised in patients with hypotension or dehydration.\n\nConcurrent Use with Nitrates:\nShould not be used together with other nitrate medications to avoid severe hypotension.\n\nOral or Gastrointestinal Ulcers:\nRarely, Nicorandil may cause ulcerations in the mouth, intestines, or skin. Treatment should be discontinued if ulceration occurs.\n\nPatients with Low Blood Volume:\nUse cautiously in individuals with hypovolemia or those on diuretics.\n\nDriving and Machinery:\nDizziness or light-headedness may occur; avoid driving until effects are known.\n\nPregnancy and Lactation:\nShould be used only if prescribed by a physician when the potential benefits outweigh the risks.\n\nPossible Side Effects\n\nNicorandil is generally safe but may cause some side effects, particularly at the start of therapy or with higher doses. Common and rare adverse reactions include:\n\nCommon Side Effects:\n\nHeadache (due to vasodilation)\n\nFlushing or warmth sensation\n\nDizziness or light-headedness\n\nNausea or mild stomach upset\n\nFatigue or weakness\n\nLess Common / Rare Side Effects:\n\nHypotension (low blood pressure)\n\nPalpitations or tachycardia\n\nMouth ulcers, anal ulcers, or skin ulceration (uncommon but serious — discontinue if occurs)\n\nRash or allergic reaction\n\nVisual disturbances (rare and usually reversible)\n\nIf any severe reaction or persistent discomfort occurs, medical attention should be sought promptly.\n\nDrug Interactions\n\nAvoid concomitant use with nitrates or phosphodiesterase type-5 inhibitors (e.g., Sildenafil, Tadalafil), as it may cause a dangerous fall in blood pressure.\n\nCaution with antihypertensive drugs or diuretics, which may enhance hypotensive effects.\n\nAlcohol consumption can potentiate dizziness or hypotension and should be limited.\n\nStorage and Handling\n\nStore below 30°C, protected from moisture and direct sunlight.\n\nKeep out of reach of children.\n\nDo not use tablets past the expiry date or if the packaging is damaged.\n\nConclusion\n\nNicorandil Tablets 5 mg offer a modern and effective approach to managing angina pectoris, providing reliable relief through their dual-action mechanism. By combining nitrate-like vasodilation with potassium channel opening, Nicorandil ensures both oxygen supply improvement and reduction of cardiac workload — the cornerstone of angina management.\n\nIt is well-tolerated, fast-acting, and suitable for long-term therapy, making it a preferred choice for patients with chronic stable angina. Regular use under medical supervision helps reduce the frequency of chest pain, improve physical endurance, and enhance the overall quality of life in individuals with coronary artery disease.", "price": 381.0, "discountamount": 115.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2202, "imageuri": "https://productimages.withfloats.com/actual/69142c03b53db80943abd33d.png", "tileimageuri": "https://productimages.withfloats.com/tile/69142c03b53db80943abd33d.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-12T06:40:55.795Z", "updatedon": "2025-11-12T06:40:55.795Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/nicorandil-tablets-5mg/2202", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Steris Healthcare Pvt Ltd", "category": "CARDIOLOGYRANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false } ], "hasmoreitems": false, "isapirequest": false, "totalresults": 27, "query": null, "floatingpoint": null }