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"description": "Risedronate Sodium Tablets IP 35 mg\n\nMaintaining strong and healthy bones becomes increasingly important with age, especially for individuals at risk of osteoporosis or bone loss. Risedronate Sodium Tablets IP 35 mg is a clinically proven medication widely prescribed to strengthen bones, reduce fracture risk, and improve overall skeletal health. If you are considering this treatment, this buyer-focused guide will help you understand everything—from how it works to its benefits, dosage, precautions, and what to check before purchasing.\n\nWhat are Risedronate Sodium Tablets IP 35 mg?\n\nRisedronate Sodium Tablets IP 35 mg contains risedronate sodium, a medication that belongs to a class called bisphosphonates. These drugs are specifically designed to prevent bone breakdown and increase bone density.\n\nIt is commonly used to treat and prevent the following:\n\nOsteoporosis in postmenopausal women\nOsteoporosis in men\nBone loss due to long-term steroid use\nPaget’s disease of bone\n\nThis once-weekly dosage (35 mg) is convenient and effective for long-term bone health management.\n\nHow Do Risedronate Sodium Tablets IP 35 mg Work?\n\nBones are constantly being renewed through a process called bone remodeling, where old bone is broken down and new bone is formed. In conditions like osteoporosis, bone breakdown occurs faster than formation, leading to weak and fragile bones.\n\nMechanism of Action:\nRisedronate inhibits osteoclasts (cells responsible for bone breakdown)\nSlows down bone loss\nHelps maintain or increase bone density\nReduces the risk of fractures, especially in the spine and hips\n\nBy restoring balance in bone remodeling, this medication strengthens bones over time.\n\nKey Benefits of Risedronate Sodium Tablets IP 35 mg\n1. Strengthens Bones\n\nHelps increase bone mineral density, making bones stronger and less prone to fractures.\n\n2. Reduces Fracture Risk\n\nSignificantly lowers the risk of spine, hip, and other bone fractures.\n\n3. Convenient Weekly Dosage\n\nThe 35 mg tablet is typically taken once a week, improving patient compliance.\n\n4. Effective for Long-Term Use\n\nSuitable for ongoing treatment under medical supervision.\n\n5. Proven Clinical Safety\n\nWidely used and trusted by healthcare professionals worldwide.\n\nWho Should Consider Buying Risedronate Sodium Tablets IP 35 mg?\n\nThis medication is suitable for:\n\nPostmenopausal women at risk of osteoporosis\nMen diagnosed with low bone density\nPatients on long-term corticosteroid therapy\nIndividuals with a history of fractures due to weak bones\nPatients diagnosed with Paget’s disease\n\nImportant: Always consult a healthcare professional before starting this medication.\n\nDosage and Administration\n\nProper usage is crucial to ensure effectiveness and reduce side effects.\n\nGeneral Guidelines:\nUsually taken once weekly (same day each week)\nTake the tablet first thing in the morning\nSwallow with a full glass of plain water (not juice or milk)\nTake on an empty stomach\nImportant Instructions:\nDo not lie down for at least 30 minutes after taking the tablet\nAvoid eating or drinking anything else for 30 minutes\nDo not crush or chew the tablet\n\nFollowing these instructions helps prevent irritation of the esophagus and improves absorption.\n\nPossible Side Effects\n\nLike all medications, Risedronate Sodium Tablets IP 35 mg may cause side effects.\n\nCommon Side Effects:\nStomach pain\nIndigestion\nNausea\nJoint or muscle pain\nLess Common but Serious Side Effects:\nDifficulty swallowing\nSevere chest pain\nJaw pain (rare, associated with osteonecrosis)\nUnusual thigh bone fractures (rare)\n\nIf you experience severe or persistent symptoms, seek medical attention immediately.\n\nPrecautions and Warnings\n\nBefore using this medication, consider the following:\n\nMedical Conditions:\nInform your doctor if you have esophageal disorders\nPatients with kidney problems should use caution\nLow calcium levels should be corrected before starting treatment\nPregnancy and Breastfeeding:\nNot recommended unless prescribed\nConsult your doctor for guidance\nDrug Interactions:\n\nRisedronate may interact with the following:\n\nCalcium supplements\nAntacids\nIron supplements\n\nThese should be taken at a different time of day to avoid interference with absorption.\n\nStorage Instructions\n\nTo maintain the quality of the medication:\n\nStore in a cool, dry place\nKeep away from moisture and sunlight\nMaintain temperature below 25°C\nKeep out of reach of children\nBuying Guide: What to Check Before Purchase\n\nWhen purchasing Risedronate Sodium Tablets IP 35 mg, ensure the following:\n\nIt is prescribed by a qualified doctor\nThe product is from a reputable pharmaceutical brand\nPackaging is intact and properly sealed\nExpiry date is valid\nPurchased from a licensed pharmacy\n\nBulk buyers and distributors should source from trusted suppliers to ensure consistent quality and authenticity.\n\nWhy Choose Risedronate Sodium Tablets IP 35 mg?\n\nThis medication stands out due to:\n\nProven effectiveness in improving bone health\nConvenient once-weekly dosing\nReduced risk of fractures\nLong-term safety when monitored\nCost-effective treatment option\n\nFor individuals seeking reliable osteoporosis management, this tablet offers a practical and effective solution.\n\nFrequently Asked Questions (FAQs)\n1. How long does it take to see results?\n\nBone improvement may take several months, but fracture risk reduction begins earlier.\n\n2. Can I take it daily?\n\nNo, the 35 mg dose is typically taken once weekly.\n\n3. Is it safe for long-term use?\n\nYes, under medical supervision with regular monitoring.\n\n4. Can I take it with food?\n\nNo, it should be taken on an empty stomach for proper absorption.\n\n5. Do I need supplements with this medication?\n\nDoctors often recommend calcium and vitamin D supplements alongside treatment.\n\nLifestyle Tips for Better Bone Health\n\nTo maximize the benefits of Risedronate Sodium Tablets IP 35 mg:\n\nMaintain a calcium-rich diet\nEnsure adequate vitamin D intake\nEngage in weight-bearing exercises\nAvoid smoking and excessive alcohol consumption\nGet regular bone density tests\nConclusion\n\nRisedronate Sodium Tablets IP 35 mg is a trusted and effective solution for managing osteoporosis and improving bone strength. With its proven ability to reduce fracture risk and enhance bone density, it plays a vital role in long-term skeletal health.\n\nFor best results, follow your doctor’s instructions carefully, maintain a healthy lifestyle, and ensure regular medical check-ups. Choosing the right treatment today can significantly improve your bone health and overall quality of life in the future.",
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"description": "ESMOSTRUM IT: Comprehensive Product Guide\nProduct Overview\nESMOSTRUM IT is an advanced pharmaceutical formulation that combines two potent active ingredients—Esomeprazole and Itopride—to provide comprehensive relief from gastrointestinal disorders. This dual-action medication represents a significant advancement in the management of acid-related digestive conditions and motility disorders. By combining a proton pump inhibitor with a prokinetic agent, ESMOSTRUM IT addresses both the underlying causes and symptomatic manifestations of various digestive ailments, offering patients a complete therapeutic solution in a single, convenient dosage form.\nThe synergistic combination of Esomeprazole and Itopride makes ESMOSTRUM IT particularly effective for individuals suffering from gastroesophageal reflux disease (GERD), functional dyspepsia, and other conditions where both excessive acid production and impaired gastric motility contribute to discomfort and disease progression.\nActive Pharmaceutical Ingredients\nEsomeprazole\nEsomeprazole is the S-isomer of omeprazole and belongs to the class of medications known as proton pump inhibitors (PPIs). It works by specifically and irreversibly blocking the hydrogen-potassium adenosine triphosphatase enzyme system (the proton pump) located in the gastric parietal cells. This mechanism effectively reduces gastric acid secretion, providing sustained relief from acid-related symptoms and allowing damaged esophageal and gastric tissue to heal.\nItopride\nItopride is a prokinetic agent that enhances gastrointestinal motility through a dual mechanism of action. It acts as both a dopamine D2 receptor antagonist and an acetylcholinesterase inhibitor. By blocking dopamine receptors, it removes the inhibitory effect of dopamine on gastrointestinal motility, while its acetylcholinesterase inhibition increases acetylcholine levels, further promoting coordinated gastric contractions and improved gastric emptying.\nTherapeutic Uses and Indications\nESMOSTRUM IT is prescribed for a wide range of gastrointestinal conditions where both acid suppression and enhanced motility are therapeutically beneficial:\nGastroesophageal Reflux Disease (GERD)\nESMOSTRUM IT provides exceptional relief for patients suffering from GERD, a chronic condition where stomach acid frequently flows back into the esophagus. The esomeprazole component reduces acid production, while itopride improves the tone of the lower esophageal sphincter and accelerates gastric emptying, thereby reducing the frequency and severity of reflux episodes.\nFunctional Dyspepsia\nFor patients experiencing persistent or recurrent upper abdominal discomfort without an identifiable organic cause, ESMOSTRUM IT addresses multiple pathophysiological mechanisms. It relieves symptoms such as early satiety, postprandial fullness, epigastric pain, and bloating by normalizing gastric acid levels and improving gastric accommodation and emptying.\nPeptic Ulcer Disease\nESMOSTRUM IT aids in the healing of gastric and duodenal ulcers by creating an optimal healing environment through sustained acid suppression. The prokinetic action of itopride helps prevent stasis of gastric contents, which can exacerbate ulcer symptoms.\nNon-Ulcer Dyspepsia\nMany patients experience dyspeptic symptoms without evidence of ulceration. ESMOSTRUM IT effectively manages these symptoms by addressing both acid hypersecretion and delayed gastric emptying, two key factors in non-ulcer dyspepsia.\nGastroparesis-Related Symptoms\nIn conditions where gastric emptying is significantly delayed, the itopride component of ESMOSTRUM IT helps restore more normal gastric motility patterns, reducing associated symptoms like nausea, vomiting, and abdominal distension.\nKey Benefits and Advantages\nDual Mechanism of Action\nThe primary advantage of ESMOSTRUM IT lies in its comprehensive approach to gastrointestinal health. Rather than addressing only acid production or motility in isolation, this combination therapy tackles both aspects simultaneously, providing more complete symptom relief and better therapeutic outcomes.\nSuperior Acid Suppression\nEsomeprazole offers more consistent and prolonged acid suppression compared to many other acid-reducing medications. It provides sustained relief throughout the day and night, allowing patients to experience fewer breakthrough symptoms and better quality of life.\nEnhanced Gastric Motility\nThe itopride component specifically targets motility issues without crossing the blood-brain barrier significantly, meaning it provides prokinetic benefits with minimal central nervous system side effects. This results in improved gastric emptying, reduced bloating, and decreased feelings of fullness after meals.\nRapid Symptom Relief\nMany patients experience noticeable improvement in their symptoms within the first few days of treatment with ESMOSTRUM IT. The combination therapy addresses multiple symptom pathways simultaneously, leading to faster and more comprehensive relief.\nImproved Quality of Life\nBy effectively managing symptoms such as heartburn, regurgitation, nausea, bloating, and early satiety, ESMOSTRUM IT significantly enhances patients' daily functioning and overall well-being. Patients report better sleep quality, improved dietary tolerance, and reduced anxiety related to their digestive symptoms.\nConvenient Dosing\nThe combination of two active ingredients in a single formulation improves medication adherence by reducing pill burden. Patients appreciate the simplicity of taking one medication instead of multiple separate preparations.\nMucosal Healing Properties\nBeyond symptom relief, ESMOSTRUM IT promotes actual healing of damaged esophageal and gastric mucosa. The reduced acid environment created by esomeprazole allows inflamed and eroded tissue to regenerate properly.\nReduced Risk of Complications\nBy effectively controlling acid reflux and improving gastric emptying, ESMOSTRUM IT helps prevent potential complications of chronic GERD, such as esophageal strictures, Barrett's esophagus, and respiratory complications from aspiration.\nDosage and Administration\nESMOSTRUM IT should be taken exactly as prescribed by a healthcare professional. Typically, the medication is administered orally, preferably before meals to optimize its therapeutic effects. The standard dosing regimen usually involves once or twice daily administration, though individual requirements may vary based on the severity of the condition and patient response.\nThe medication should be swallowed whole with water and should not be crushed, chewed, or split, as this may affect the drug's release mechanism and therapeutic efficacy. Patients should maintain regular dosing schedules to ensure optimal acid suppression and motility enhancement throughout the day.\nSide Effects and Safety Considerations\nLike all medications, ESMOSTRUM IT may cause side effects in some individuals, though not everyone experiences them. Understanding potential adverse effects helps patients identify and report concerning symptoms promptly.\nCommon Side Effects\nGastrointestinal Effects: Some patients may experience diarrhea, constipation, abdominal pain, nausea, or flatulence, particularly during initial treatment. These effects are usually mild and often resolve as the body adjusts to the medication.\nHeadache: Mild to moderate headaches occur in a small percentage of patients and typically diminish with continued use.\nDizziness: Some individuals may experience lightheadedness or dizziness, particularly when standing up quickly.\nDry Mouth: Reduced saliva production may occur, leading to oral dryness and discomfort.\nLess Common Side Effects\nSkin Reactions: Rash, itching, or other dermatological manifestations may develop in sensitive individuals.\nSleep Disturbances: Some patients report insomnia or unusual dreams while taking the medication.\nIncreased Prolactin Levels: Itopride may cause mild elevation in prolactin levels, though clinical manifestations are rare.\nTaste Alterations: Changes in taste perception or metallic taste may occur temporarily.\nSerious Side Effects (Rare)\nWhile uncommon, certain serious adverse effects require immediate medical attention:\n\nSevere allergic reactions including difficulty breathing, facial swelling, or severe skin reactions\nSevere diarrhea that persists or contains blood\nIrregular heartbeat or palpitations\nMuscle weakness or pain\nSeizures or tremors\nSigns of liver problems including jaundice, dark urine, or persistent nausea\n\nLong-Term Considerations\nExtended use of proton pump inhibitors like esomeprazole has been associated with certain risks that patients should discuss with their healthcare providers:\n\nPotential reduction in calcium, magnesium, and vitamin B12 absorption\nSlightly increased risk of bone fractures with prolonged use\nPossible increased susceptibility to certain gastrointestinal infections\nRare cases of kidney problems\n\nRegular monitoring and periodic assessment by healthcare professionals help minimize these risks while maintaining therapeutic benefits.\nPrecautions and Contraindications\nPatients should inform their healthcare provider about all existing medical conditions, particularly liver disease, kidney problems, osteoporosis, low magnesium levels, or any gastrointestinal bleeding. ESMOSTRUM IT may interact with certain medications, including blood thinners, antifungals, HIV medications, and certain antibiotics. A complete medication review ensures safe and effective therapy.\nPregnant or breastfeeding women should only use ESMOSTRUM IT under strict medical supervision, as the safety profile in these populations requires careful consideration of potential risks and benefits.\nLifestyle Recommendations\nFor optimal therapeutic outcomes, patients taking ESMOSTRUM IT should complement their medication regimen with appropriate lifestyle modifications:\n\nAvoid trigger foods that exacerbate acid reflux, such as spicy foods, citrus, chocolate, caffeine, and alcohol\nMaintain a healthy body weight to reduce abdominal pressure\nEat smaller, more frequent meals rather than large portions\nAvoid lying down immediately after eating; wait at least two to three hours\nElevate the head of the bed if nighttime symptoms occur\nQuit smoking, as tobacco use significantly worsens reflux symptoms\nManage stress through relaxation techniques, as stress can exacerbate digestive symptoms\n\nConclusion\nESMOSTRUM IT represents a sophisticated and effective pharmaceutical solution for individuals struggling with complex gastrointestinal disorders involving both acid hypersecretion and impaired motility. By combining the powerful acid-suppressing capabilities of esomeprazole with the prokinetic benefits of itopride, this medication offers comprehensive symptom management that addresses the multifaceted nature of digestive disorders.",
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"name": "Cinacalcet 60 mg Tablet",
"description": "CINASELECT 60: Comprehensive Guide to Cinacalcet 60 mg Tablets\nProduct Overview\nCINASELECT 60 is a pharmaceutical formulation containing Cinacalcet hydrochloride 60 mg as its active ingredient. This medication represents a significant advancement in the management of calcium metabolism disorders, particularly in patients with chronic kidney disease and parathyroid conditions. As a calcimimetic agent, CINASELECT 60 works by mimicking the action of calcium on tissues, helping to restore hormonal balance and mineral homeostasis in the body.\nThe 60 mg dosage strength offers an effective therapeutic option for patients requiring moderate to higher-level intervention in managing parathyroid hormone levels and associated calcium imbalances. CINASELECT 60 is manufactured under strict quality control standards, ensuring consistency, purity, and efficacy in every tablet.\nUnderstanding How CINASELECT 60 Works\nCINASELECT 60 operates through a sophisticated mechanism that targets the calcium-sensing receptors located on the surface of parathyroid gland cells. These receptors play a crucial role in regulating parathyroid hormone secretion, which in turn controls calcium and phosphorus levels in the bloodstream.\nWhen you take CINASELECT 60, the active ingredient cinacalcet binds to these calcium-sensing receptors, increasing their sensitivity to extracellular calcium. This enhanced sensitivity tricks the parathyroid glands into “thinking” there is more calcium present in the blood than there actually is. As a result, the glands reduce their production and release of parathyroid hormone (PTH).\nBy lowering PTH levels, CINASELECT 60 subsequently reduces calcium levels in the blood and decreases the amount of phosphorus absorbed from the intestines. This cascade effect helps restore the delicate mineral balance that is often disrupted in patients with kidney disease or parathyroid disorders.\nPrimary Therapeutic Uses\nSecondary Hyperparathyroidism in Chronic Kidney Disease\nThe primary indication for CINASELECT 60 is the treatment of secondary hyperparathyroidism in adult patients with chronic kidney disease (CKD) who are on dialysis. When kidneys fail to function properly, they cannot adequately regulate calcium and phosphorus levels, leading to excessive parathyroid hormone production. This condition can result in serious complications including bone disease, cardiovascular calcification, and increased mortality risk.\nCINASELECT 60 helps manage this condition by controlling PTH levels, thereby reducing the risk of bone complications such as osteitis fibrosa cystica and preventing the dangerous deposition of calcium in blood vessels and soft tissues.\nHypercalcemia in Parathyroid Carcinoma\nCINASELECT 60 is also indicated for treating hypercalcemia (elevated blood calcium levels) in patients with parathyroid carcinoma, a rare malignant tumor of the parathyroid glands. In these cases, the medication helps control the dangerously high calcium levels that can lead to kidney stones, bone pain, digestive issues, and neurological symptoms.\nPrimary Hyperparathyroidism\nFor patients with severe hypercalcemia due to primary hyperparathyroidism who cannot undergo parathyroidectomy or for whom surgery has failed, CINASELECT 60 offers a valuable medical management option. This provides relief for patients who are not surgical candidates due to advanced age, comorbidities, or other contraindications.\nKey Benefits of CINASELECT 60\nEffective PTH Control\nClinical studies have demonstrated that CINASELECT 60 significantly reduces parathyroid hormone levels in a dose-dependent manner. This reduction helps prevent the cascade of complications associated with elevated PTH, including bone mineral loss and cardiovascular calcification.\nImproved Calcium-Phosphorus Balance\nBy reducing PTH secretion, CINASELECT 60 helps normalize serum calcium and phosphorus levels. This is particularly important in dialysis patients, where mineral imbalances can lead to serious complications affecting bone health, cardiovascular function, and overall quality of life.\nReduced Cardiovascular Risk\nElevated calcium and phosphorus levels contribute to vascular calcification, a major risk factor for cardiovascular disease in patients with chronic kidney disease. By managing these mineral levels, CINASELECT 60 may help reduce the risk of cardiovascular complications, which are the leading cause of death in dialysis patients.\nBone Health Preservation\nUncontrolled secondary hyperparathyroidism leads to renal osteodystrophy, a condition characterized by abnormal bone metabolism. CINASELECT 60 helps protect bone integrity by normalizing PTH levels, potentially reducing fracture risk and preserving bone mineral density.\nAlternative to Surgery\nFor patients with primary hyperparathyroidism or parathyroid carcinoma who cannot undergo surgery, CINASELECT 60 provides an effective medical management option. This is particularly valuable for elderly patients or those with multiple comorbidities that make surgery risky.\nQuality of Life Improvement\nBy controlling symptoms associated with hypercalcemia and hyperparathyroidism, such as bone pain, muscle weakness, fatigue, and digestive issues, CINASELECT 60 can significantly improve patients' overall quality of life and functional capacity.\nConvenient Oral Administration\nCINASELECT 60 is administered orally, making it more convenient than injectable alternatives. This allows for outpatient management and reduces the burden on healthcare facilities and patients.\nPotential Side Effects and Adverse Reactions\nCommon Side Effects\nPatients taking CINASELECT 60 may experience several common side effects, which typically include nausea and vomiting, occurring in approximately 20-30% of patients. These gastrointestinal symptoms are usually mild to moderate and may improve over time as the body adjusts to the medication.\nDiarrhea is another frequent complaint, affecting roughly 20% of users. Some patients also report muscle pain or myalgia, dizziness, loss of appetite, and asthenia (general weakness or fatigue).\nSerious Side Effects Requiring Medical Attention\nHypocalcemia: The most significant risk associated with CINASELECT 60 is the development of low calcium levels in the blood. Severe hypocalcemia can lead to paresthesias (tingling sensations), muscle cramps or spasms, tetany, seizures, and QT interval prolongation on electrocardiogram, which can predispose to dangerous heart rhythm abnormalities.\nGastrointestinal Bleeding: There have been reports of gastrointestinal hemorrhage in patients taking cinacalcet, particularly in those with risk factors such as gastritis, ulcers, or concurrent use of other medications that increase bleeding risk.\nAdynamic Bone Disease: Oversuppression of PTH can lead to adynamic bone disease, a condition where bone turnover becomes abnormally low, potentially weakening bones despite normalized calcium levels.\nCardiovascular Effects: Some patients may experience worsening heart failure or arrhythmias, particularly if hypocalcemia develops. Close monitoring is essential in patients with underlying cardiovascular disease.\nAllergic Reactions: Though rare, hypersensitivity reactions including rash, urticaria, and angioedema have been reported.\nPrecautions and Contraindications\nCINASELECT 60 should not be used in patients with serum calcium levels below the normal range. It requires careful dose adjustment and monitoring in patients with hepatic impairment. The medication may interact with drugs metabolized by the CYP2D6 enzyme system and with medications that affect gastric pH.\nPregnant or breastfeeding women should use CINASELECT 60 only if clearly needed, as its safety in these populations has not been fully established. Regular monitoring of serum calcium, phosphorus, and PTH levels is essential throughout treatment.\nDosage and Administration Guidelines\nCINASELECT 60 should be taken orally with food or shortly after a meal, as this improves absorption and reduces gastrointestinal side effects. Tablets should be swallowed whole and not crushed, chewed, or divided.\nThe typical starting dose for secondary hyperparathyroidism is lower than 60 mg, with gradual titration based on PTH and calcium levels. The 60 mg strength is often used as part of the dose escalation process or as a maintenance dose once optimal PTH control is achieved.\nDose adjustments should be made no more frequently than every two to four weeks, as it takes this long to see the full effect of a dose change on PTH levels. Treatment should be individualized based on laboratory values and clinical response.\nMonitoring Requirements\nPatients on CINASELECT 60 require regular monitoring of serum calcium, phosphorus, and intact PTH levels. Calcium levels should be checked within one week of starting treatment or after any dose adjustment, and then monthly once stable. PTH levels should be measured one to four weeks after initiation or dose adjustment, then every one to three months during maintenance therapy.\nAdditionally, patients should be monitored for signs and symptoms of hypocalcemia, particularly during the initial treatment period. Electrocardiogram monitoring may be appropriate in patients at risk for QT prolongation.\nStorage and Handling\nCINASELECT 60 should be stored at room temperature, away from moisture and direct sunlight. The medication should be kept in its original container with the lid tightly closed to protect from humidity. Keep out of reach of children and pets. Do not use past the expiration date printed on the package.\nConclusion\nCINASELECT 60 (Cinacalcet 60 mg) represents a valuable therapeutic option in the management of secondary hyperparathyroidism associated with chronic kidney disease, hypercalcemia in parathyroid carcinoma, and primary hyperparathyroidism in patients who cannot undergo surgery. Its unique mechanism as a calcimimetic agent provides effective control of parathyroid hormone secretion, helping to restore mineral balance and prevent serious complications.\nThe benefits of CINASELECT 60 extend beyond simple laboratory value normalization. By controlling PTH, calcium, and phosphorus levels, this medication helps preserve bone health, reduce cardiovascular calcification risk, and improve overall quality of life for patients dealing with complex metabolic disorders. For patients who are not surgical candidates, CINASELECT 60 offers hope and effective symptom management.\nHowever, like all medications, CINASELECT 60 must be used judiciously under close medical supervision. The risk of hypocalcemia and other potential side effects necessitates regular laboratory monitoring and open communication between patients and healthcare providers. Patients should report any concerning symptoms promptly and attend all scheduled follow-up appointments.",
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"description": "LINALIGIP EMPAMET (Empagliflozin, Linagliptin, and Metformin Hydrochloride ER Tablets) stands out as a comprehensive triple therapy for adults with type 2 diabetes mellitus, combining three synergistic agents to tackle hyperglycemia from multiple angles. This once-daily extended-release formulation simplifies adherence while delivering robust glycemic control, weight management, and cardiovascular protection. Patients often seek it for its convenience in managing blood sugar levels when diet, exercise, and single agents fall short.\n\n\nProduct Description and Composition\nLINALIGIP EMPAMET features Empagliflozin (typically 10-25mg), Linagliptin (5 mg), and Metformin Hydrochloride ER (up to 1000mg) in a single tablet, designed for prolonged release to minimize gastrointestinal upset. Empagliflozin, an SGLT2 inhibitor, blocks glucose reabsorption in the kidneys, promoting its excretion via urine. Linagliptin, a DPP-4 inhibitor, enhances incretin hormones like GLP-1 to boost insulin secretion and suppress glucagon. Metformin ER reduces hepatic glucose production and improves insulin sensitivity without hypoglycemia risk.\n\n\nThis unique blend from Steris Healthcare ensures steady drug delivery over 24 hours, reducing peak-trough fluctuations for stable HbA1c reductions of 1.5-2.0%. The extended-release metformin coats the tablet core, dissolving gradually in the intestines for better tolerability compared to immediate-release forms. Ideal for Indian patients facing rising diabetes prevalence, it addresses insulin resistance, postprandial spikes, and caloric overload holistically.\n\n\nMechanism of Action\nThe triple mechanism targets key diabetes pathways: Empagliflozin inhibits SGLT2 in proximal renal tubules, lowering blood glucose by 70-90g daily through glycosuria, independent of insulin. Linagliptin selectively binds DPP-4, prolonging GLP-1 and GIP activity to stimulate glucose-dependent insulin release from beta cells and curb glucagon-mediated gluconeogenesis. Metformin activates AMPK in hepatocytes, inhibiting gluconeogenesis while enhancing peripheral glucose uptake.\n\n\nSynergy amplifies effects—SGLT2 inhibition provides insulin-independent control, DPP-4 boosts prandial responses, and metformin tackles fasting hyperglycemia—resulting in complementary HbA1c drops without overlapping toxicities. Clinical data show this combination yields superior efficacy over dual therapies, with added osmotic diuresis aiding fluid balance.\n\n\nUses and Indications\nLINALIGIP EMPAMET treats type 2 diabetes in adults, as adjunct to diet and exercise, especially when metformin alone or dual therapy inadequately controls glycemia. Primary uses include newly diagnosed patients needing intensification, those with obesity (due to weight loss from glycosuria), and high-risk cardiovascular profiles benefiting from empagliflozin's heart protection. It excels in managing postprandial hyperglycemia, fasting glucose, and preventing complications like nephropathy.\n\n\nPrescribed for patients intolerant to other agents or requiring simplified regimens, it suits Indian demographics with high metabolic syndrome rates. Not for type 1 diabetes or ketoacidosis; renal function (eGFR >45 mL/min) guides initiation.\n\n\nKey Benefits\nLINALIGIP EMPAMET offers multifaceted advantages for long-term diabetes management:\n\nSuperior Glycemic Control: Achieves 1.8% HbA1c reduction in trials, outperforming monotherapies by targeting multiple defects.\n\n\nWeight Loss: Empagliflozin induces 3-5kg loss via caloric excretion, countering metformin's neutral effect.\n\n\nCardiovascular and Renal Protection: Reduces major adverse cardiac events (MACE) by 14% and slows CKD progression, per EMPA-REG outcomes.\n\n\nLow Hypoglycemia Risk: Glucose-dependent actions of linagliptin and empagliflozin minimize lows, unlike sulfonylureas.\n\n\nConvenience: Single-tablet ER dosing improves compliance, vital for busy lifestyles in Jaipur and beyond.\n\n\nBlood Pressure Reduction: Mild diuretic effect lowers systolic BP by 3-5 mmHg.\n\n\nThese benefits enhance quality of life, reducing fatigue, neuropathy risks, and healthcare costs.\n\nSide Effects\nCommon side effects mirror individual components but occur less due to synergy:\n\nGastrointestinal: Metformin ER causes less nausea/diarrhea (10-15%) than IR forms; titrate slowly.\n\n\nGenitourinary: Empagliflozin raises UTI/genital mycotic infection risk (5-10%), managed with hygiene.\n\n\nVolume Depletion: Orthostatic hypotension in 2-3%, especially with diuretics.\n\n\nSerious effects include lactic acidosis (rare, <1/100,000 with metformin in eGFR >30), ketoacidosis (euglycemic, 0.1%), and acute kidney injury. Monitor for dehydration, pancreatitis signs, or bullous pemphigoid with linagliptin. Hypersensitivity rash or bone fractures warrant discontinuation.\n\n\nSide Effect Category\tFrequency\tManagement\nNausea and Diarrhea\tCommon (10%)\tTake with food, slow titration \n\nUTI/Mycotic Infections\tCommon (7%)\tHydration, antifungals \n\nHypoglycemia\tRare (<2%)\tWith insulin, dose adjust \n\nLactic Acidosis\tVery Rare.\tAvoid in renal/hepatic failure \n\nKetoacidosis\tRare (0.1%)\tCheck ketones if nausea \n\nDosage and Administration\nStart with Empagliflozin 10mg/Linagliptin 5mg/Metformin ER 1000mg once daily with morning meal to optimize absorption and reduce GI effects. Titrate metformin to 2000mg max based on tolerance; empagliflozin to 25mg if needed. Swallow whole; no crushing. Adjust for renal impairment (eGFR 30-45: max metformin 1000mg; <30 contraindicated). Elderly start low due to volume sensitivity.\n\n\nMissed dose: Take soon if less than 12 hours late; skip otherwise. Discontinue pre-surgery or contrast use.\n\nPrecautions and Warnings\nAssess eGFR before and 3-6 months after initiation; hold if <45. Caution in dehydration, heart failure, or liver disease risks lactic acidosis. Educate on ketoacidosis symptoms (nausea, fatigue) despite normal glucose. Avoid excessive alcohol; monitor BP in hypertensives. Pregnancy category D—use insulin instead. Breastfeeding is contraindicated.\n\n\nDrug interactions: Adding sulfonylureas/insulin heightens hypoglycemia; rifampin reduces linagliptin levels; ritonavir boosts empagliflozin exposure.\n\nFrequently Asked Questions\nWhat is LINALIGIP EMPAMET used for?\nControls type 2 diabetes via triple action on glucose excretion, incretins, and insulin sensitivity.\n\nDoes it cause weight gain?\nNo—it promotes 2-4 kg loss, unlike some antidiabetics.\n\n\nSafe for kidneys?\nRenal-protective; monitor eGFR.\n\n\nHypoglycemia risk?\nMinimal without sulfonylureas.\n\nConclusion\nLINALIGIP EMPAMET revolutionizes type 2 diabetes care with its potent, convenient triple therapy, delivering glycemic mastery, weight benefits, and cardioprotection unmatched by singles or duos. Backed by landmark trials, it empowers patients toward complication-free lives when integrated with lifestyle changes. Consult physicians for personalized dosing to harness its full potential safely.",
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"description": "ENZULAMIDE 160\nEnzalutamide 160mg capsules represent a breakthrough in targeted therapy for advanced prostate cancer, specifically designed to inhibit androgen receptor signaling at multiple levels, slowing cancer progression even in castration-resistant cases. This oral medication, typically taken as a single daily 160mg dose (four 40mg capsules), binds directly to the androgen receptor, preventing nuclear translocation and DNA binding, which starves hormone-dependent prostate tumors of growth signals. Patients with metastatic castration-resistant prostate cancer (mCRPC), non-metastatic CRPC (nmCRPC), or metastatic castration-sensitive prostate cancer (mCSPC) benefit from its ability to delay disease advancement, reduce PSA levels, and extend progression-free survival.\n\nAdministered continuously without cycling, enzalutamide 160mg maintains steady-state plasma levels for consistent anti-tumor activity, making it suitable for long-term management alongside standard care. Its role expands beyond initial hormone therapy failures, offering hope where traditional options falter.\n\nProduct Uses: Targeting Advanced Prostate Cancer\nEnzalutamide 160mg primarily treats metastatic castration-resistant prostate cancer (mCRPC) post-chemotherapy or in pre-chemo settings, where tumors grow despite low testosterone. It excels in non-metastatic CRPC (nmCRPC) by delaying metastasis onset, with trials showing median metastasis-free survival exceeding 3 years versus placebo. In mCSPC, combination with ADT prolongs overall survival by months, reducing radiographic progression risks.\n\nClinicians prescribe it for high-risk patients with rising PSA despite androgen deprivation therapy (ADT), as it shrinks tumors, alleviates bone pain from metastases, and improves quality of life metrics like urinary function and fatigue scores. Regular monitoring via PSA doubling time and imaging guides ongoing use.\n\nKey Benefits of Enzalutamide 160mg\nEnzalutamide 160mg delivers transformative outcomes through potent androgen blockade:\n\nExtended Progression-Free Survival: PROSPER trial data indicate 97% risk reduction in metastasis or death for nmCRPC; ENZAMET shows 33% overall survival benefit in mCSPC.\n\nPSA Response Rates: Over 78% achieve ≥50% PSA decline in mCRPC, correlating with radiographic stability and symptom palliation.\n\nBone Metastasis Control: Lowers skeletal-related events by 30-40%, preserving mobility and reducing fracture incidence when paired with bone agents.\n\nQuality of Life Preservation: FACT-P scores improve in pain, appetite, and emotional well-being domains, enabling patients to maintain daily activities longer.\n\nOral Convenience: Once-daily dosing without food restrictions enhances adherence compared to infusions or multi-pill regimens.\n\nThese advantages position enzalutamide 160mg as a cornerstone in modern prostate cancer protocols, particularly for fit patients tolerating its profile.\n\nSide Effects: Managing Risks Effectively\nWhile effective, enzalutamide 160mg carries side effects from androgen suppression and receptor antagonism, affecting 70-90% of users to varying degrees. Most prove manageable with supportive care, dose holds, or adjustments, but vigilance remains essential.\n\nCommon Side Effects\nFrequently reported (≥10%) issues include:\n\nFatigue/Asthenia (30-40%): Profound tiredness impacting daily tasks; rest, exercise, and stimulants like modafinil help.\n\nHot Flashes (20-25%): Sudden heat waves; cooling strategies and SSRIs alleviate symptoms.\n\nMusculoskeletal Pain (15-30%): Joint/muscle aches; NSAIDs or physical therapy provide relief.\n\nDiarrhea/Constipation (10-20%): Alternating bowel changes; fiber, hydration, and laxatives balance gut function.\n\nHypertension (10-15%): Blood pressure elevations; routine monitoring and antihypertensives control spikes.\n\nThese transient effects often peak in first months, diminishing with acclimation.\n\nSerious Side Effects\nSeek immediate care for:\n\nSeizures (1-2%): Risk higher with brain history; anticonvulsants or discontinuation advised.\n\nFalls/Fractures (10-15%): Due to weakness, dizziness; fall precautions and bone density scans mitigate.\n\nCardiovascular Events: Myocardial infarction, strokes (2-5%); lipid/BP checks essential.\n\nPosterior Reversible Encephalopathy Syndrome (PRES): Rare confusion, seizures, vision loss; MRI confirms.\n\nSevere Skin Reactions: Stevens-Johnson syndrome; rash monitoring critical.\n\nBaseline neurological assessments and quarterly labs optimize safety.\n\nDosage and Administration Guidelines\nSwallow four 40mg capsules whole once daily at the same time, with or without food, totaling 160mg. No dose reductions below 120mg recommended; hold for grade 3-4 toxicity, resuming at prior dose once resolved. Hepatic impairment (Child-Pugh B/C) warrants caution; renal adjustments unnecessary. Continue indefinitely unless progression or intolerance occurs.\n\nPrecautions and Monitoring\nAvoid in seizure history without prophylaxis; women (especially pregnant) must not handle due to teratogenicity. Strong CYP2A4 inducers/inhibitors alter exposure—adjust accordingly. Elderly patients face amplified fall risks; annual DEXA scans track bone health. Regular PSA, testosterone, CBC, liver enzymes, and ECGs ensure proactive management.\n\nConclusion\nEnzalutamide 160mg stands as a pivotal advancement in prostate cancer care, offering substantial delays in disease progression, symptom control, and survival gains for patients facing hormone-resistant stages. By meticulously balancing its robust benefits against manageable side effects through vigilant monitoring and supportive measures, individuals regain control over their health journey. Consult oncologists to integrate this therapy seamlessly, tailoring it to personal profiles for optimal, life-extending results\nEmail: info@sterispharma.com / contact@sterispharma.com\nCall/WhatsApp: 7877551268, 7849827488\n\n\n\n\n\n\n\n",
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"description": "Enzalutamide 40 mg capsules represent a breakthrough in targeted therapy for advanced prostate cancer, particularly in metastatic castration-resistant prostate cancer (mCRPC) and metastatic castration-sensitive prostate cancer (mCSPC). This second-generation androgen receptor inhibitor works by disrupting multiple steps in the androgen signaling pathway, offering patients a chance to slow disease progression, reduce tumor burden, and extend survival even after other treatments fail. Administered as a once-daily oral capsule, enzalutamide 40 mg provides four capsules per day (total 160 mg), making it convenient for long-term use in clinical settings where hormone therapy alone proves insufficient.\n\nPatients often turn to enzalutamide when facing rising PSA levels despite androgen deprivation therapy (ADT), experiencing bone pain, or dealing with cancer spread to lymph nodes or distant sites. Its high affinity for androgen receptors—5-8 times stronger than first-generation antiandrogens like bicalutamide—ensures potent blockade without agonist activity, translating to real-world benefits like delayed chemotherapy needs and improved quality of life during treatment.\n\nProduct Use and Indications\nEnzalutamide 40 mg primarily treats metastatic castration-resistant prostate cancer (mCRPC) in patients previously treated with docetaxel or progressing despite ADT. The FDA and EMA approvals extend to non-metastatic CRPC (nmCRPC) with high-risk biochemical recurrence and metastatic castration-sensitive prostate cancer (mCSPC) alongside ADT, based on landmark trials like AFFIRM, PREVAIL, PROSPER, and ARCHES.\n\nKey uses include:\n\nSlowing tumor growth in hormone-refractory stages by inhibiting androgen-driven proliferation.\n\nReducing skeletal-related events like fractures or spinal cord compression in bone metastases.\n\nDelaying progression to chemotherapy in pre-chemotherapy mCRPC, with PREVAIL showing 17-month median radiographic progression-free survival (rPFS) versus 4 months for placebo.\n\nIn mCSPC, ARCHES trial data demonstrated 61% risk reduction in progression or death when combined with ADT. Clinicians monitor PSA response (≥50% decline in 70-80% of patients) and imaging every 3 months to assess efficacy.\n\nMechanism of Action\nEnzalutamide 40 mg exerts a threefold blockade on androgen receptor (AR) signaling: it competitively inhibits androgen binding to AR (with affinity rivaling dihydrotestosterone), prevents nuclear translocation of the ligand-receptor complex, and disrupts DNA binding and coactivator recruitment at androgen response elements. This comprehensive inhibition downregulates oncogenes like TMPRSS2-ERG fusion genes common in prostate cancer, inducing apoptosis and halting cell proliferation without lowering systemic testosterone levels.\n\nUnlike earlier antiandrogens, enzalutamide avoids partial agonist effects, ensuring pure antagonism even in AR-overexpressing tumors. Its active metabolite, N-desmethyl enzalutamide (via CYP2C8), contributes 30% to activity, with steady-state levels achieved in 4 weeks.\n\nKey Benefits\nExtended Progression-Free Survival: In PREVAIL (pre-chemo mCRPC), median overall survival reached 32.4 months versus 30.2 for placebo; PROSPER (nmCRPC) delayed metastasis by 22 months.\n\nPSA Response and Tumor Shrinkage: 78% PSA90 response rate; radiographic responses in 29% with measurable disease.\n\nQuality of Life Preservation: Delays pain progression (hazard ratio 0.40) and chemotherapy (by 17 months), maintaining daily function.\n\nBone Protection: Reduces fractures by 30% in high-risk patients via AR inhibition in osteoblasts.\n\nCombination Synergy: Enhances ADT efficacy in mCSPC, cutting death risk by 33% per ARCHES.\n\nThese benefits position enzalutamide 40 mg as a cornerstone in modern prostate cancer protocols, especially for fit patients tolerating oral therapy.\n\nSide Effects\nEnzalutamide 40 mg carries a manageable profile, with most effects dose-related and reversible upon discontinuation.\n\nCommon Side Effects\nFatigue/Asthenia (34-50%): Often mild, peaking in first months; rest and nutrition help.\n\nArthralgia/Myalgia (14-21%): Joint/muscle pain managed with NSAIDs.\n\nHot Flashes (20%): Androgen blockade mimic; hydration aids.\n\nHeadache/Dizziness (12-19%): Transient; avoid driving if severe.\n\nHypertension (6-13%): Monitor BP monthly; antihypertensives as needed.\n\nGI Issues (diarrhea 12%, nausea 11%): Antiemetics support compliance.\n\nSerious Side Effects\nSeizures (0.9%): Highest risk in epileptics or brain mets; EEG baseline, avoid triggers.\n\nPosterior Reversible Encephalopathy (PRES): Rare (<0.1%); headache, confusion—MRI confirms.\n\nFalls/Fractures (15% increased risk): Due to weakness/falls; DEXA scans recommended.\n\nCardiac Events (2-5%): MI/arrhythmias; ECG monitoring in CVD history.\n\nHepatic Injury (1%): ALT/AST elevation; monthly labs first 3 months.\n\nDiscontinuation occurs in 8-10%; supportive care mitigates most.\n\nDosage and Administration\nStandard dose: 160 mg (four 40 mg capsules) once daily, with or without food. Swallow intact; no crushing. Adjust for CYP2A4 inducers (e.g., rifampin—increase to 240 mg) or strong inhibitors (reduce to 80 mg). Continue until progression/toxicity; no dose interruptions beyond 28 days without reassessment.\n\nPrecautions and Monitoring\nContraindicated in pregnancy (teratogenic; absolute contraception for men/ partners). Screen for seizure history; CYP2C8/3A4 interactions (e.g., ketoconazole). Baseline LFTs, PSA, testosterone; imaging q8-12 weeks. Elderly (>75) monitor falls.\nConclusion\nEnzalutamide 40 mg stands as a transformative therapy, empowering prostate cancer patients with prolonged control over aggressive disease through precise AR inhibition. Balancing robust efficacy—evidenced by landmark trials delaying metastasis and death—with proactive side effect management, it enhances survival and daily living. Patients achieve meaningful milestones, from family events to travel, underscoring its role in personalized oncology. Consult oncologists for integration into care plans, ensuring optimal outcomes in this challenging journey.\nEmail: info@sterispharma.com / contact@sterispharma.com\nCall/WhatsApp: 7877551268, 7849827488\n\n\n\n\n\n\n\n\n",
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"description": "Indomethacin and Paracetamol Capsules: Complete Guide to Uses, Benefits, Composition, and Safety\nWhat Are Indomethacin and Paracetamol Capsules?\n\nIndomethacin and Paracetamol Capsules are a combination medication used to relieve pain, reduce inflammation, and control fever associated with various acute and chronic conditions. This combination brings together the powerful anti-inflammatory action of Indomethacin and the well-established pain-relieving and fever-reducing properties of Paracetamol, making it an effective treatment option for patients experiencing musculoskeletal pain, arthritis-related discomfort, headaches, post-operative pain, and fever.\n\nThe dual-action formula is designed to provide faster and more comprehensive symptom relief compared to single-ingredient therapies. Healthcare professionals often prescribe this combination when pain and inflammation occur together and require effective management.\n\nComposition of Indomethacin and Paracetamol Capsules\n\nThe formulation contains the following active pharmaceutical ingredients:\n\nIndomethacin\n\nA potent non-steroidal anti-inflammatory drug (NSAID) that helps reduce inflammation, swelling, stiffness, and pain.\n\nParacetamol (Acetaminophen)\n\nAn analgesic and antipyretic agent used to relieve pain and reduce fever.\n\nTogether, these ingredients provide a balanced approach to managing pain, inflammation, and elevated body temperature.\n\nHow Do Indomethacin and Paracetamol Capsules Work?\n\nIndomethacin and Paracetamol Capsules work through complementary mechanisms to deliver effective relief from painful and inflammatory conditions.\n\nIndomethacin Action\n\nIndomethacin inhibits cyclooxygenase (COX) enzymes responsible for producing prostaglandins, which are chemicals that contribute to inflammation, pain, and swelling. By reducing prostaglandin production, Indomethacin helps alleviate discomfort and improve mobility.\n\nParacetamol Action\n\nParacetamol acts primarily within the central nervous system to block pain signals and regulate body temperature. It effectively reduces fever and enhances overall pain control.\n\nThe combination provides broader symptom relief by addressing both peripheral inflammation and central pain perception.\n\nComposition Benefits of Indomethacin and Paracetamol Capsules\n\nThe combination offers multiple therapeutic benefits:\n\nEffective pain management\nStrong anti-inflammatory action\nFever reduction\nImproved mobility and comfort\nFaster symptom relief\nBetter patient compliance through combination therapy\nMechanism of Each Ingredient\nIndomethacin\nMechanism of Action\n\nIndomethacin belongs to the NSAID class and works by inhibiting cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes. These enzymes are involved in the production of prostaglandins that cause inflammation and pain.\n\nTherapeutic Effects\nReduces inflammation\nRelieves joint pain\nMinimizes swelling\nImproves flexibility and movement\nControls pain associated with arthritis and musculoskeletal disorders\nParacetamol\nMechanism of Action\n\nParacetamol acts centrally by inhibiting pain-mediating pathways in the brain and affecting the hypothalamic heat-regulating center.\n\nTherapeutic Effects\nReduces fever\nRelieves mild to moderate pain\nImproves patient comfort\nEnhances overall pain management when combined with NSAIDs\nKey Benefits of Indomethacin and Paracetamol Capsules\nPowerful Pain Relief\n\nThe combination effectively manages moderate to severe pain caused by inflammatory and non-inflammatory conditions.\n\nDual Action Formula\n\nProvides both anti-inflammatory and analgesic effects for comprehensive symptom control.\n\nEffective Fever Reduction\n\nParacetamol helps lower elevated body temperature associated with infections and inflammatory diseases.\n\nImproved Joint Mobility\n\nIndomethacin reduces stiffness and swelling, making movement easier and more comfortable.\n\nFaster Recovery Support\n\nBy controlling pain and inflammation, the capsules help patients return to normal daily activities sooner.\n\nConvenient Combination Therapy\n\nCombines two trusted therapeutic agents into a single dosage form for improved treatment adherence.\n\nUses of Indomethacin and Paracetamol Capsules\n\nHealthcare professionals may prescribe Indomethacin and Paracetamol Capsules for various conditions, including:\n\nOsteoarthritis\n\nHelps relieve:\n\nJoint pain\nSwelling\nStiffness\nReduced mobility\nRheumatoid Arthritis\n\nProvides symptomatic relief from chronic inflammation and discomfort.\n\nAnkylosing Spondylitis\n\nHelps reduce spinal pain and stiffness associated with inflammatory conditions.\n\nAcute Musculoskeletal Pain\n\nUseful for:\n\nMuscle injuries\nLigament strains\nSports injuries\nBack pain\nGouty Arthritis\n\nIndomethacin is particularly effective in managing acute gout attacks and associated inflammation.\n\nDental Pain\n\nProvides relief from pain and swelling following dental procedures or infections.\n\nPost-Operative Pain\n\nSupports pain management after surgical interventions.\n\nFever Associated with Painful Conditions\n\nParacetamol helps control elevated body temperature while Indomethacin addresses inflammation.\n\nHeadache and Migraine\n\nMay be used under medical supervision for inflammatory headaches and migraine-related discomfort.\n\nWhy Choose Indomethacin and Paracetamol Capsules?\nComprehensive Symptom Relief\n\nThe combination targets pain, inflammation, and fever simultaneously.\n\nTrusted Active Ingredients\n\nBoth Indomethacin and Paracetamol have long-established clinical use in pain management.\n\nEnhanced Pain Control\n\nCombining two different mechanisms of action often provides superior relief compared to monotherapy.\n\nEffective for Inflammatory Conditions\n\nParticularly beneficial in arthritis, gout, and musculoskeletal disorders.\n\nImproved Patient Convenience\n\nA single capsule provides multiple therapeutic benefits, reducing the need for separate medications.\n\nSuitable for Short-Term Pain Management\n\nOften prescribed for acute painful conditions requiring rapid symptom control.\n\nImportant Safety Information\n\nBefore using Indomethacin and Paracetamol Capsules, consider the following precautions:\n\nUse Only as Prescribed\n\nTake the medication exactly as directed by your healthcare professional.\n\nAvoid Exceeding Recommended Dosage\n\nOveruse may increase the risk of serious side effects, including liver damage and gastrointestinal complications.\n\nGastrointestinal Precautions\n\nIndomethacin may cause:\n\nStomach irritation\nGastric ulcers\nGastrointestinal bleeding\n\nPatients with a history of ulcers should consult their physician before use.\n\nLiver Disease Warning\n\nParacetamol should be used cautiously in patients with liver impairment.\n\nKidney Function Monitoring\n\nPatients with kidney disease may require dose adjustments and regular monitoring.\n\nCardiovascular Considerations\n\nNSAIDs may increase cardiovascular risks in certain patients.\n\nPregnancy and Breastfeeding\n\nUse only if specifically recommended by a healthcare provider after evaluating the benefits and risks.\n\nAlcohol Consumption\n\nAvoid alcohol while taking this medication as it may increase the risk of liver and stomach-related side effects.\n\nDrug Interactions\n\nInform your healthcare provider if you are taking:\n\nBlood thinners\nOther NSAIDs\nCorticosteroids\nAntihypertensive medicines\nDiuretics\nAntidiabetic medications\nPossible Side Effects\n\nLike all medications, Indomethacin and Paracetamol Capsules may cause side effects in some individuals.\n\nCommon side effects include:\n\nNausea\nVomiting\nIndigestion\nStomach pain\nHeadache\nDizziness\nDrowsiness\nHeartburn\n\nSeek immediate medical attention if you experience:\n\nSevere allergic reactions\nDifficulty breathing\nBlack or bloody stools\nSevere abdominal pain\nYellowing of the skin or eyes\nUnusual bleeding\nStorage Instructions\nStore in a cool, dry place.\nProtect from moisture and direct sunlight.\nKeep the capsules in their original packaging.\nKeep out of reach of children.\nDo not use after the expiry date mentioned on the package.\nConclusion\n\nIndomethacin and Paracetamol Capsules are an effective combination therapy for managing pain, inflammation, and fever associated with a wide range of medical conditions. The anti-inflammatory power of Indomethacin combined with the analgesic and antipyretic effects of Paracetamol provides comprehensive symptom relief and improved patient comfort.",
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"description": "Latanoprost Ophthalmic Solution – Trusted Eye Drop Treatment for Glaucoma and Ocular Hypertension\nLatanoprost Ophthalmic Solution\n\nIf you are looking for an effective treatment to lower elevated eye pressure and protect your vision, Latanoprost Ophthalmic Solution is one of the most widely prescribed medications for glaucoma and ocular hypertension. Known for its proven efficacy, convenient once-daily dosing, and long-term benefits, Latanoprost helps reduce intraocular pressure (IOP), which is a major risk factor for optic nerve damage and vision loss.\n\nMillions of patients worldwide rely on Latanoprost Ophthalmic Solution to manage chronic eye conditions that can gradually affect eyesight. By improving the natural drainage of fluid from the eye, this medication helps maintain healthy eye pressure levels and supports long-term ocular health.\n\nWhether you have recently been diagnosed with glaucoma or are searching for a reliable eye pressure-lowering treatment, this comprehensive guide will help you understand the uses, benefits, mechanism of action, dosage, side effects, and key advantages of Latanoprost Ophthalmic Solution.\n\nWhat Is Latanoprost Ophthalmic Solution?\n\nLatanoprost Ophthalmic Solution is a prescription eye medication belonging to a class of drugs known as prostaglandin analogs. It is primarily used to reduce elevated intraocular pressure in patients with:\n\nOpen-angle glaucoma\nOcular hypertension\nChronic eye pressure management\nRisk of glaucoma progression\n\nElevated pressure inside the eye can damage the optic nerve over time, leading to permanent vision impairment. Latanoprost Ophthalmic Solution helps prevent this damage by facilitating better fluid drainage from the eye.\n\nBecause of its strong effectiveness and convenient dosing schedule, ophthalmologists often recommend Latanoprost as a first-line treatment for glaucoma management.\n\nHow Latanoprost Ophthalmic Solution Works\n\nThe eye continuously produces a fluid known as aqueous humor. This fluid nourishes the eye and helps maintain its shape. Normally, the fluid drains naturally through specialized pathways.\n\nIn glaucoma and ocular hypertension, fluid drainage becomes inadequate, causing pressure to build up inside the eye.\n\nMechanism of Action\n\nLatanoprost works by:\n\nIncreasing the outflow of aqueous humor from the eye\nEnhancing natural fluid drainage through the uveoscleral pathway\nReducing intraocular pressure effectively\nMaintaining healthier pressure levels throughout the day\n\nBy lowering eye pressure, Latanoprost helps reduce stress on the optic nerve and decreases the risk of progressive vision loss.\n\nIts pressure-lowering effect typically lasts for 24 hours, making once-daily administration highly effective for most patients.\n\nUses of Latanoprost Ophthalmic Solution\n1. Open-Angle Glaucoma\n\nOpen-angle glaucoma is the most common form of glaucoma worldwide. Latanoprost helps lower eye pressure and slow the progression of optic nerve damage.\n\n2. Ocular Hypertension\n\nPatients with elevated intraocular pressure but no significant optic nerve damage can benefit from early pressure reduction to prevent glaucoma development.\n\n3. Long-Term Eye Pressure Control\n\nLatanoprost is commonly prescribed for ongoing management of chronic eye conditions requiring consistent pressure regulation.\n\n4. Vision Preservation\n\nBy reducing pressure within the eye, Latanoprost helps protect vision and maintain overall eye health over time.\n\n5. Prevention of Glaucoma Progression\n\nMaintaining controlled intraocular pressure significantly lowers the likelihood of disease advancement and associated vision loss.\n\nKey Benefits of Latanoprost Ophthalmic Solution\nEffective Intraocular Pressure Reduction\n\nLatanoprost is highly effective in lowering elevated eye pressure and maintaining stable control.\n\nOnce-Daily Dosing\n\nThe medication typically requires only one application per day, making treatment simple and convenient.\n\nLong-Lasting Action\n\nA single dose can provide pressure-lowering effects for up to 24 hours.\n\nSupports Optic Nerve Protection\n\nReducing eye pressure helps safeguard the optic nerve from long-term damage.\n\nImproved Treatment Compliance\n\nThe easy dosing schedule encourages consistent medication use and better treatment outcomes.\n\nWidely Trusted by Eye Specialists\n\nLatanoprost has been extensively studied and remains one of the most prescribed glaucoma medications globally.\n\nHelps Preserve Vision\n\nRegular use contributes to long-term visual health and reduces the risk of glaucoma-related blindness.\n\nWho Can Benefit from Latanoprost Ophthalmic Solution?\n\nLatanoprost Ophthalmic Solution may be suitable for:\n\nAdults diagnosed with open-angle glaucoma\nPatients with ocular hypertension\nIndividuals requiring long-term eye pressure management\nPatients seeking convenient once-daily therapy\nIndividuals at risk of optic nerve damage\nPatients requiring preventive glaucoma treatment\n\nYour ophthalmologist will determine whether Latanoprost is appropriate based on your eye condition and medical history.\n\nWhy Buyers Choose Latanoprost Ophthalmic Solution\n\nWhen purchasing glaucoma medication, patients prioritize effectiveness, convenience, and safety. Latanoprost Ophthalmic Solution consistently meets these expectations.\n\nBuyer Intent Advantages\nProven glaucoma treatment\nTrusted by ophthalmologists worldwide\nConvenient once-daily application\nEffective pressure reduction\nLong-term vision protection\nEasy incorporation into daily routines\nSuitable for chronic use\nClinically established safety profile\n\nThese advantages make Latanoprost Ophthalmic Solution one of the most preferred choices for glaucoma management.\n\nHow to Use Latanoprost Ophthalmic Solution\n\nFor best results, use the medication exactly as prescribed by your healthcare provider.\n\nGeneral Directions\nWash your hands thoroughly.\nShake the bottle if instructed.\nTilt your head backward.\nPull down the lower eyelid gently.\nInstill one drop into the affected eye.\nClose your eyes for one to two minutes.\nAvoid touching the dropper tip to any surface.\nReplace the cap securely after use.\n\nLatanoprost is usually administered once daily in the evening unless otherwise directed by your ophthalmologist.\n\nImportant Precautions\n\nBefore using Latanoprost Ophthalmic Solution, inform your healthcare provider if you have:\n\nEye inflammation\nEye infections\nHistory of eye surgery\nMacular edema\nContact lens use\nSevere allergies\nOther ongoing eye conditions\n\nRegular eye examinations are important to monitor treatment effectiveness and eye health.\n\nPossible Side Effects of Latanoprost Ophthalmic Solution\n\nLike all medications, Latanoprost may cause side effects in some individuals.\n\nCommon Side Effects\nEye redness\nMild irritation\nBurning sensation\nItching\nTemporary blurred vision\nIncreased tearing\nDry eye sensation\nLong-Term Cosmetic Changes\n\nSome users may experience:\n\nDarkening of the iris color\nIncreased eyelash growth\nThickening of eyelashes\nDarkening of eyelid skin\n\nThese changes usually occur gradually and may become permanent with prolonged use.\n\nLess Common Side Effects\nEye pain\nSensitivity to light\nSwelling around the eye\nVision disturbances\n\nSeek immediate medical attention if severe allergic reactions or significant vision changes occur.\n\nStorage Instructions\n\nProper storage helps maintain medication quality and effectiveness.\n\nRecommended Storage Guidelines\nStore at the temperature recommended on the product label.\nKeep away from direct sunlight.\nProtect from excessive heat.\nKeep the bottle tightly closed when not in use.\nDo not use after the expiration date.\nKeep out of reach of children.\n\nAlways follow manufacturer-specific storage instructions.\n\nFrequently Asked Questions\nCan Latanoprost cure glaucoma?\n\nNo. Latanoprost does not cure glaucoma but helps control eye pressure and slow disease progression.\n\nHow quickly does it lower eye pressure?\n\nPressure reduction typically begins within a few hours of administration, with maximum effects developing over continued use.\n\nCan it be used long term?\n\nYes. Latanoprost is commonly prescribed for long-term management of glaucoma and ocular hypertension.\n\nWhat happens if I miss a dose?\n\nTake the next scheduled dose as directed. Do not use extra drops to compensate for a missed application.\n\nCan contact lens users use Latanoprost?\n\nYes, but contact lenses may need to be removed before application and reinserted after the recommended waiting period advised by your doctor.\n\nConclusion\n\nLatanoprost Ophthalmic Solution is a highly effective and widely trusted treatment for reducing elevated intraocular pressure associated with glaucoma and ocular hypertension. By enhancing the natural drainage of fluid from the eye, it helps maintain healthy eye pressure levels, protect the optic nerve, and preserve long-term vision.\n\nIts once-daily dosing, proven clinical effectiveness, and established safety profile make it a preferred choice among ophthalmologists and patients alike. Whether you are newly diagnosed with glaucoma or seeking reliable long-term eye pressure management, Latanoprost Ophthalmic Solution offers a dependable solution for protecting your eyesight and supporting overall ocular health.",
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"description": "Travoprost Timolol Eye Drops\n\nIf you are looking for a trusted and clinically proven solution to manage elevated eye pressure associated with glaucoma or ocular hypertension, Travoprost Timolol Eye Drops offer an effective dual-action treatment. This combination medication is widely prescribed by ophthalmologists to help reduce intraocular pressure (IOP), protect the optic nerve, and lower the risk of vision loss caused by progressive eye diseases.\n\nTravoprost Timolol Eye Drops combine two powerful active ingredients—Travoprost, a prostaglandin analog, and Timolol, a beta-blocker. Together, they work through complementary mechanisms to provide superior pressure control compared to many single-agent treatments. For patients who require enhanced management of eye pressure, this combination offers convenience, efficacy, and long-term protection.\n\nThis comprehensive guide explains the uses, benefits, mechanism of action, dosage guidance, side effects, and reasons why Travoprost Timolol Eye Drops are a preferred choice among eye care professionals and patients.\n\nWhat Are Travoprost Timolol Eye Drops?\n\nTravoprost Timolol Eye Drops are prescription ophthalmic drops used primarily to reduce increased intraocular pressure in individuals suffering from:\n\nOpen-angle glaucoma\nOcular hypertension\nChronic glaucoma management\nElevated eye pressure resistant to monotherapy\n\nHigh eye pressure can gradually damage the optic nerve, leading to permanent vision loss if left untreated. Travoprost Timolol Eye Drops help maintain healthy eye pressure levels and preserve visual function.\n\nThe combination includes:\n\nTravoprost\n\nTravoprost belongs to a class of medications known as prostaglandin analogs. It works by increasing the natural drainage of fluid from the eye.\n\nTimolol\n\nTimolol is a non-selective beta-blocker that reduces the production of aqueous humor, the fluid responsible for maintaining pressure within the eye.\n\nTogether, these ingredients provide a comprehensive approach to lowering intraocular pressure.\n\nHow Travoprost Timolol Eye Drops Work\n\nThe effectiveness of Travoprost Timolol Eye Drops comes from their dual-action mechanism.\n\nTravoprost Action\n\nTravoprost improves the outflow of aqueous humor through the uveoscleral pathway. As more fluid drains from the eye, intraocular pressure decreases.\n\nTimolol Action\n\nTimolol reduces the amount of aqueous humor produced by the ciliary body inside the eye. Lower fluid production helps maintain optimal pressure levels.\n\nCombined Benefits\n\nBy simultaneously increasing fluid drainage and decreasing fluid production, Travoprost Timolol Eye Drops provide stronger and more consistent pressure control than either component alone.\n\nThis dual mechanism makes them particularly effective for patients requiring significant reduction in intraocular pressure.\n\nUses of Travoprost Timolol Eye Drops\n1. Open-Angle Glaucoma\n\nOpen-angle glaucoma is one of the most common forms of glaucoma. Travoprost Timolol Eye Drops help lower eye pressure and reduce the risk of optic nerve damage.\n\n2. Ocular Hypertension\n\nPatients with elevated eye pressure but no visible optic nerve damage can benefit from pressure reduction to prevent future complications.\n\n3. Long-Term Glaucoma Management\n\nThese eye drops are often prescribed as part of a long-term treatment plan to maintain stable eye pressure levels.\n\n4. Inadequate Response to Single Therapy\n\nPatients who do not achieve sufficient pressure control with a single medication may be switched to this combination therapy.\n\n5. Prevention of Vision Loss\n\nConsistent control of intraocular pressure helps minimize the progression of glaucoma-related vision impairment.\n\nKey Benefits of Travoprost Timolol Eye Drops\nPowerful Intraocular Pressure Reduction\n\nThe dual-action formula provides significant and sustained lowering of eye pressure.\n\nTwo Medications in One Drop\n\nCombining two proven therapies into a single formulation improves convenience and treatment adherence.\n\nReduced Risk of Optic Nerve Damage\n\nMaintaining healthy eye pressure levels helps protect the optic nerve from progressive damage.\n\nLong-Lasting Effectiveness\n\nMany patients achieve effective pressure control with once-daily administration as prescribed by their ophthalmologist.\n\nEnhanced Treatment Compliance\n\nUsing a combination product may reduce the need for multiple eye medications, simplifying treatment routines.\n\nProven Clinical Performance\n\nBoth Travoprost and Timolol have extensive clinical use and are well-established in glaucoma management.\n\nSupports Long-Term Vision Preservation\n\nRegular use can help slow disease progression and maintain visual function.\n\nWho Should Consider Travoprost Timolol Eye Drops?\n\nTravoprost Timolol Eye Drops may be suitable for:\n\nAdults diagnosed with open-angle glaucoma\nPatients with ocular hypertension\nIndividuals requiring stronger eye pressure control\nPatients not adequately controlled on single-agent therapy\nPeople seeking a convenient combination treatment\nIndividuals at risk of glaucoma progression\n\nOnly an eye specialist can determine whether this medication is appropriate based on individual eye health and medical history.\n\nHow to Use Travoprost Timolol Eye Drops\n\nFor best results, use the eye drops exactly as prescribed.\n\nGeneral Application Steps\nWash your hands thoroughly.\nShake the bottle if instructed.\nTilt your head backward.\nPull down the lower eyelid gently.\nInstill the prescribed number of drops.\nClose your eyes for one to two minutes.\nAvoid touching the dropper tip to any surface.\nReplace the cap securely after use.\n\nIf using multiple eye medications, allow an interval between applications according to your healthcare provider's instructions.\n\nWhy Buyers Choose Travoprost Timolol Eye Drops\n\nWhen purchasing glaucoma medications, patients and caregivers often prioritize effectiveness, convenience, and long-term protection. Travoprost Timolol Eye Drops are a preferred option because they address multiple treatment goals simultaneously.\n\nBuyer-Focused Advantages\nEffective reduction of elevated eye pressure\nConvenient dual-action formula\nTrusted glaucoma treatment\nReduced medication burden\nSupports optic nerve health\nLong-term disease management\nWidely prescribed by ophthalmologists\nProven safety and efficacy profile\n\nThese qualities make Travoprost Timolol Eye Drops a reliable choice for glaucoma and ocular hypertension management.\n\nPrecautions Before Using Travoprost Timolol Eye Drops\n\nBefore starting treatment, inform your healthcare provider if you have:\n\nAsthma\nChronic obstructive pulmonary disease (COPD)\nHeart disease\nSlow heart rate\nDiabetes\nThyroid disorders\nHistory of severe allergic reactions\nEye infections or recent eye surgery\n\nTimolol may be absorbed into the bloodstream and can affect certain medical conditions. Regular monitoring may be required.\n\nPossible Side Effects of Travoprost Timolol Eye Drops\n\nLike all medications, Travoprost Timolol Eye Drops may cause side effects in some individuals.\n\nCommon Side Effects\nEye redness\nMild burning or stinging\nTemporary blurred vision\nEye irritation\nIncreased tear production\nDry eyes\nForeign body sensation\nTravoprost-Related Effects\nGradual darkening of the iris\nIncreased eyelash growth\nChanges in eyelash thickness\nEyelid skin darkening\nTimolol-Related Effects\nSlower heart rate\nFatigue\nDizziness\nShortness of breath in susceptible individuals\n\nSeek immediate medical attention if severe allergic reactions, chest pain, breathing difficulties, or significant vision changes occur.\n\nStorage Instructions\n\nTo maintain effectiveness and sterility:\n\nStore at room temperature.\nProtect from excessive heat and direct sunlight.\nKeep the bottle tightly closed.\nDo not use after the expiration date.\nKeep out of reach of children.\n\nAlways follow the storage recommendations provided on the product label.\n\nFrequently Asked Questions\nCan Travoprost Timolol Eye Drops cure glaucoma?\n\nNo. Glaucoma cannot currently be cured, but these eye drops help control eye pressure and slow disease progression.\n\nHow long does it take to work?\n\nThe medication begins lowering eye pressure soon after administration, with continued benefits during regular use.\n\nCan contact lens wearers use these drops?\n\nContact lenses may need to be removed before application and reinserted later according to your doctor's guidance.\n\nIs daily use necessary?\n\nYes. Consistent daily use is important for maintaining stable intraocular pressure and protecting vision.\n\nConclusion\n\nTravoprost Timolol Eye Drops are an advanced combination therapy designed to effectively manage elevated intraocular pressure associated with glaucoma and ocular hypertension. By combining the pressure-lowering effects of Travoprost and Timolol, these eye drops provide comprehensive, long-lasting control that helps protect the optic nerve and preserve vision.\n\nWhether you require stronger glaucoma management or a more convenient treatment option, Travoprost Timolol Eye Drops offer a trusted solution backed by extensive clinical experience. With benefits including powerful pressure reduction, simplified dosing, and support for long-term eye health, they remain a preferred choice for patients seeking reliable glaucoma care.",
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