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"description": "CARDULES ISMN SR 30 tablets provide sustained-release Isosorbide Mononitrate IP 30mg, a nitrate medication designed for long-term management of angina in patients with coronary artery disease. This formulation from Steris Healthcare Pvt Ltd ensures steady vasodilation to improve heart blood flow and reduce chest pain episodes. It supports daily activities by minimizing oxygen demand on the heart muscle.\nProduct Overview\nCARDULES ISMN SR 30 contains Isosorbide Mononitrate IP 30mg in a sustained-release matrix, allowing once-daily dosing for consistent therapeutic levels over 12-24 hours. The tablet's extended-release technology prevents peak-trough fluctuations common in immediate-release forms, promoting better patient compliance. Each film-coated tablet delivers precise bioavailability, with the active metabolite nitric oxide activating guanylate cyclase to boost cyclic GMP, relaxing vascular smooth muscle primarily in veins.\n\nThis mechanism reduces preload (venous return to the heart) and afterload (arterial resistance), easing cardiac workload without significantly affecting heart rate. Unlike short-acting nitrates for acute relief, CARDULES ISMN SR 30 targets prophylaxis in chronic stable angina, often prescribed alongside beta-blockers or calcium channel blockers. Available in strips of 10 tablets, it undergoes rigorous quality testing at Steris facilities to meet IP standards, ensuring purity and stability.\n\nKey Uses\nCARDULES ISMN SR 30 primarily prevents angina pectoris in coronary artery disease, where narrowed vessels limit oxygen supply during exertion. Patients experience fewer chest pain attacks during walking, climbing stairs, or stress.\n\nIt manages chronic stable angina by enhancing myocardial perfusion, suitable for long-term therapy in adults over 18. Healthcare providers may use it adjunctively for coronary spasm or post-myocardial infarction prophylaxis to stabilize symptoms.\n\nIn select cases, it aids heart failure management by offloading the heart, though not as monotherapy. Always initiate under cardiology supervision with dose titration to tolerance.\n\nMajor Benefits\nThe sustained-release profile offers 24-hour protection with single morning dosing, improving adherence and lifestyle quality for active patients. It boosts exercise tolerance by 20-30% in trials, allowing longer physical efforts without angina onset.\n\nBy dilating vessels, it decreases ischemia risk, potentially lowering hospitalization rates for acute episodes. Compared to placebo, users report halved attack frequency within weeks, enhancing daily productivity and emotional well-being.\n\nBenefit\tMechanism\tPatient Outcome\nAngina Prevention\tVasodilation reduces preload/afterload \tFewer attacks, better exertion capacity\nSteady Relief\tSR formulation maintains levels \tOnce-daily convenience, no fluctuations\nHeart Protection\tImproves O2 delivery \tReduced ischemia, enhanced QoL\nCompliance Boost\tSimple regimen \tHigher adherence vs multiple doses\nAdditional perks include minimal impact on blood pressure in normotensives and compatibility with anti-anginals, making it versatile in combo therapy.\n\nPotential Side Effects\nCommon effects include headache (dose-related, often transient in first week), dizziness, or flushing due to vasodilation—hydrate and rise slowly to manage. Gastrointestinal upset like nausea occurs in 5-10% initially.\n\nOrthostatic hypotension risks fainting, especially early; avoid alcohol or other vasodilators. Rare serious issues encompass severe hypotension, tachycardia, or methemoglobinemia with overdose—monitor blood pressure regularly.\n\nAllergic reactions (rash, itching) or vision changes warrant discontinuation. Contraindicated in hypotension, glaucoma, or recent PDE5 inhibitor use; caution in anemia or hypothyroidism.\n\nDosage Guidelines\nStart with 30mg once daily upon waking, swallowed whole without crushing. Titrate to 60mg if tolerated after 3-7 days, max 120mg/day. Take on empty stomach for optimal absorption; avoid late dosing to prevent nocturnal headaches.\n\nAdjust for elderly or renal/hepatic impairment. Tolerance may develop—nitrate-free interval (evening) helps sustain efficacy. Store below 30°C.\nConclusion\nCARDULES ISMN SR 30 empowers angina patients with reliable, once-daily prevention, restoring confidence in routine activities under Steris Healthcare's quality assurance. Its targeted vasodilation balances efficacy and tolerability for sustained heart health",
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"description": "AMIPULSIDE CR 400 is a prescription-based, controlled-release formulation of Amisulpride 400 mg, developed to offer sustained therapeutic effects with once-daily dosing. Manufactured to high quality standards, this medication plays a vital role in the management of both acute and chronic schizophrenic disorders. It belongs to the class of atypical antipsychotics and works by regulating the activity of certain neurotransmitters in the brain, primarily dopamine. This helps control symptoms like hallucinations, delusions, disorganized thinking, and social withdrawal associated with schizophrenia.\n\nWhat is AMIPULSIDE CR 400?\nAMIPULSIDE CR 400 contains Amisulpride, a selective dopamine D2/D3 receptor antagonist. It is primarily used in the treatment of schizophrenia, particularly effective in managing both positive symptoms (e.g., hallucinations, delusions) and negative symptoms (e.g., emotional withdrawal, apathy). The controlled-release (CR) formulation allows for steady absorption and action, improving patient compliance and reducing fluctuations in symptom control.\n\nThis medication is designed for the treatment of acute and chronic schizophrenic disorders and is often used as part of a comprehensive psychiatric care plan, including counseling and behavioral therapy.\n\nUses of AMIPULSIDE CR 400\nManagement of acute episodes of schizophrenia\n\nLong-term maintenance therapy for chronic schizophrenic disorders\n\nEffective in treating positive symptoms (e.g., hallucinations, paranoia)\n\nBeneficial in alleviating negative symptoms (e.g., lack of motivation, social withdrawal)\n\nSide Effects of AMIPULSIDE CR 400\nLike all medications, AMIPULSIDE CR 400 may cause side effects in some patients. Common side effects include:\n\nInsomnia or drowsiness\n\nWeight gain\n\nConstipation\n\nAnxiety\n\nIncreased prolactin levels (can lead to breast tenderness or menstrual changes)\n\nTremors or stiffness (extrapyramidal symptoms)\n\nSerious but rare side effects may include:\n\nNeuroleptic malignant syndrome (fever, muscle rigidity, confusion)\n\nIrregular heart rhythms\n\nSeizures\n\nSeek immediate medical help if you experience chest pain, severe dizziness, or signs of an allergic reaction.\n\nPrecautions Before Using AMIPULSIDE CR 400\nBefore starting treatment with AMIPULSIDE CR 400, inform your doctor if:\n\nYou have a history of heart disease or irregular heart rhythms\n\nYou suffer from kidney or liver dysfunction\n\nYou are pregnant, planning pregnancy, or breastfeeding\n\nYou have Parkinson’s disease\n\nYou have low potassium or magnesium levels in your blood\n\nAvoid alcohol and other central nervous system depressants while taking this medication, as they may increase drowsiness or impair alertness.\n\nDrug Interactions\nAmisulpride can interact with a variety of medications, which may enhance or diminish its therapeutic effects or increase the risk of adverse events.\n\nWhat Drugs Interact with AMIPULSIDE CR 400?\nAntiarrhythmic drugs (e.g., quinidine, amiodarone): May increase the risk of heart rhythm abnormalities\n\nCNS depressants (e.g., benzodiazepines, opioids): Increase sedation and respiratory depression risk\n\nLevodopa and dopamine agonists: Can counteract the effect of Amisulpride\n\nSSRIs (e.g., fluoxetine, paroxetine): May increase the plasma levels of Amisulpride\n\nDrugs that prolong QT interval (e.g., erythromycin, haloperidol): May raise the risk of cardiac arrhythmias\n\nDiuretics: May alter electrolyte balance, increasing risk of heart rhythm disturbances\n\nAlways disclose all medications, supplements, or herbal products you are taking to your healthcare provider before starting AMIPULSIDE CR 400.\n\nConclusion\n\nAMIPULSIDE CR 400 (Amisulpride 400 mg CR Tablet) is a clinically effective medication for individuals suffering from schizophrenia, offering reliable symptom control through its controlled-release formulation. Its ability to treat both the acute and chronic phases of the disorder makes it a cornerstone in psychiatric management. Regular monitoring and adherence to prescribed guidelines ensure optimal results and improved quality of life for patients.",
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"description": "CARDULES ISMN SR 40 is a sustained-release tablet formulated with Isosorbide Mononitrate (40 mg), a powerful nitrate-based compound used primarily in the prevention and long-term management of angina pectoris (chest pain caused by heart disease). This medication works by relaxing and widening blood vessels, allowing for improved blood flow to the heart, reducing its workload, and preventing episodes of chest pain. It is typically prescribed for patients with chronic stable angina and forms part of a long-term treatment plan for certain heart conditions.\n\n\nKey Benefits:\n\n\nHelps prevent and manage angina (chest pain) in patients with coronary artery disease.\n\nImproves blood flow to the heart muscles, reducing the risk of cardiac ischemia.\n\nDecreases the oxygen demand on the heart by reducing preload and afterload.\n\nOffers long-lasting relief with a sustained-release action for convenience and steady plasma levels.\n\nReduces the frequency of anginal attacks, enhancing quality of life and exercise tolerance.\n\n\nHow Does It Work?\n\n\nIsosorbide Mononitrate, the active ingredient in CARDULES ISMN SR 40, is converted into nitric oxide in the body. Nitric oxide activates guanylate cyclase, leading to increased levels of cyclic GMP (cGMP). This compound causes relaxation of vascular smooth muscles, primarily in the veins and arteries, resulting in vasodilation. As a result, blood flows more freely to the heart with reduced pressure, decreasing the heart's workload and helping to prevent episodes of angina. The sustained-release formulation ensures a prolonged therapeutic effect, minimizing fluctuations in drug levels throughout the day.\n\nDirections for Use\nTake CARDULES ISMN SR 40 exactly as prescribed by your doctor.\n\nSwallow the tablet whole with a glass of water, preferably at the same time each day.\n\nDo not crush, chew, or break the tablet as it is designed for slow release over time.\n\nIt is typically taken once daily, but the dosage may vary depending on individual medical conditions.\n\nAvoid taking the tablet on an empty stomach unless advised by your healthcare provider.\n\nDo not suddenly stop taking the medication without consulting your doctor.\n\n\nSide Effects:\n\n\nLike all medications, CARDULES ISMN SR 40 may cause some side effects, although not everyone experiences them. Common side effects include:\n\nHeadache (especially at the beginning of treatment).\n\nDizziness or lightheadedness.\n\nFlushing of the skin.\n\nNausea or vomiting.\n\nFatigue.\n\nLow blood pressure (hypotension).\n\nIn rare cases, severe allergic reactions or fainting may occur. Contact your healthcare provider immediately if you experience chest pain that doesn't improve, irregular heartbeat, or signs of an allergic reaction like rash, itching, or swelling.",
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