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"name": "Tedizolid Phosphate 200 mg ",
"description": "TEDIZOLINE 200 is a state-of-the-art pharmaceutical formulation containing Tedizolid Phosphate 200 mg, representing a significant advancement in the treatment of serious bacterial skin infections. This next-generation oxazolidinone antibiotic offers a powerful solution for patients battling acute bacterial skin and skin structure infections (ABSSSI), including those caused by methicillin-resistant Staphylococcus aureus (MRSA) and other resistant bacterial strains. Developed to address the growing challenge of antibiotic resistance, TEDIZOLINE 200 provides healthcare professionals with an effective therapeutic option when conventional antibiotics may fall short.\nThe active ingredient, Tedizolid Phosphate, functions as a prodrug that is rapidly converted in the body to its active form, tedizolid. This sophisticated mechanism ensures optimal bioavailability and targeted antibacterial action. Each tablet of TEDIZOLINE 200 delivers a precise 200 mg dose, carefully calibrated to provide maximum efficacy while minimizing the risk of adverse effects. The medication is available in convenient oral tablet form, offering flexibility in treatment administration and improving patient compliance compared to intravenous-only alternatives.\nClinical Applications and Therapeutic Uses\nTEDIZOLINE 200 is specifically indicated for the treatment of acute bacterial skin and skin structure infections caused by susceptible strains of various gram-positive bacteria. These infections include cellulitis, major cutaneous abscesses, and wound infections that require systemic antibiotic therapy. The medication demonstrates exceptional efficacy against problematic pathogens including Staphylococcus aureus (both methicillin-susceptible and methicillin-resistant strains), various Streptococcus species, and Enterococcus faecalis.\nHealthcare providers prescribe TEDIZOLINE 200 when patients present with complicated skin infections characterized by significant inflammation, purulent discharge, or systemic signs of infection such as fever and elevated white blood cell counts. The medication is particularly valuable in hospital settings where antibiotic-resistant organisms pose significant treatment challenges, though it is equally effective for outpatient management of appropriate cases.\nThe standard treatment duration with TEDIZOLINE 200 is notably shorter than many traditional antibiotics, typically requiring only six days of therapy. This abbreviated course represents a significant advantage, potentially improving patient adherence, reducing the risk of developing resistance, and minimizing healthcare costs while maintaining excellent clinical outcomes.\nKey Benefits and Therapeutic Advantages\nSuperior Antimicrobial Potency: TEDIZOLINE 200 exhibits exceptional bactericidal activity against resistant gram-positive organisms, making it a frontline weapon against infections that have failed to respond to first-line antibiotics. Its unique mechanism of action—inhibiting bacterial protein synthesis by binding to the 23S ribosomal RNA of the 50S subunit—prevents bacteria from producing essential proteins necessary for survival and reproduction.\nShortened Treatment Duration: Unlike conventional antibiotics that may require ten to fourteen days of therapy, TEDIZOLINE 200 achieves comparable or superior outcomes with just six days of treatment. This condensed regimen reduces the pill burden for patients, improves treatment completion rates, and decreases the opportunity for resistance development.\nFlexible Administration Options: The medication offers both oral and intravenous formulations with nearly identical bioavailability, allowing seamless transitions between routes of administration. This flexibility enables early hospital discharge with continuation of oral therapy at home, reducing healthcare costs and improving patient comfort and quality of life.\nOnce-Daily Dosing Convenience: TEDIZOLINE 200's pharmacokinetic profile supports convenient once-daily administration, simplifying treatment schedules and enhancing patient compliance. The sustained therapeutic levels achieved with this dosing frequency ensure continuous antibacterial activity throughout the treatment course.\nReduced Drug Interaction Profile: Compared to its predecessor oxazolidinone antibiotics, TEDIZOLINE 200 demonstrates minimal interactions with dietary tyramine and requires less stringent dietary restrictions. Additionally, it exhibits reduced potential for serotonin syndrome, offering improved safety when used in patients taking certain antidepressants or other serotonergic medications.\nProven Clinical Efficacy: Extensive clinical trials have demonstrated that TEDIZOLINE 200 achieves cure rates comparable to or exceeding those of vancomycin and linezolid, the traditional gold standards for treating MRSA infections. These studies confirm both the non-inferiority and, in some parameters, the superiority of tedizolid phosphate in treating complicated skin infections.\nPotential Side Effects and Safety Considerations\nWhile TEDIZOLINE 200 is generally well-tolerated, patients and healthcare providers should be aware of potential adverse effects. The most commonly reported side effects include nausea, headache, diarrhea, and vomiting, which typically manifest as mild to moderate in severity and often resolve without intervention.\nGastrointestinal disturbances affect approximately five to ten percent of patients, with nausea being the most frequent complaint. Taking the medication with food may help minimize these symptoms without compromising absorption. Headaches occur in a similar percentage of patients and usually respond well to over-the-counter analgesics.\nMore serious but less common adverse effects include myelosuppression, manifesting as decreased blood cell counts. Although TEDIZOLINE 200 demonstrates less bone marrow suppression than older oxazolidinones, monitoring of complete blood counts is recommended for treatment courses extending beyond the standard six days or in patients with pre-existing hematologic conditions.\nPeripheral and optic neuropathy have been reported with prolonged oxazolidinone use, though the shorter treatment duration of TEDIZOLINE 200 substantially reduces this risk. Patients should report any vision changes, numbness, tingling, or weakness in extremities promptly to their healthcare provider.\nClostridium difficile-associated diarrhea can occur with virtually any antibiotic, including TEDIZOLINE 200. Patients experiencing severe, persistent, or bloody diarrhea during or following treatment should seek immediate medical attention.\nHypersensitivity reactions, though rare, may occur and can range from mild rash to severe anaphylaxis. Any signs of allergic reaction warrant immediate discontinuation and appropriate medical intervention.\nConclusion\nTEDIZOLINE 200 represents a significant therapeutic advancement in the management of acute bacterial skin and skin structure infections, particularly those involving antibiotic-resistant organisms. Its potent antimicrobial activity, convenient once-daily dosing, shortened treatment duration, and improved safety profile compared to earlier oxazolidinones make it an invaluable addition to the antimicrobial arsenal. The medication addresses critical unmet needs in infectious disease management, offering effective treatment options when traditional antibiotics prove insufficient.",
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"name": "Sodium Chloride Inhalation Solution USP 3% w/v",
"description": "SODICHLOR 3% is a sterile, preservative-free hypertonic saline inhalation solution specifically formulated to help manage respiratory conditions characterized by thick, tenacious mucus secretions. This pharmaceutical-grade formulation contains 3% sodium chloride in purified water, offering a concentration three times higher than normal saline, designed to work through osmotic principles to improve airway clearance and respiratory function.\nAs a trusted therapeutic agent in respiratory care, SODICHLOR 3% represents a non-antibiotic approach to managing chronic respiratory conditions, making it an invaluable tool for patients suffering from cystic fibrosis, chronic obstructive pulmonary disease (COPD), bronchiectasis, and other conditions where mucus clearance is compromised. The solution is administered via nebulization, allowing the medication to reach deep into the bronchial passages where it can exert its therapeutic effects most effectively.\nHow SODICHLOR 3% Works\nThe mechanism of action behind SODICHLOR 3% is elegantly simple yet highly effective. When nebulized and inhaled, the hypertonic saline solution creates an osmotic gradient in the airways. This means that the higher salt concentration in the solution draws water from the surrounding tissues into the airway surface liquid layer. This influx of water hydrates the mucus, making it less viscous and sticky, which significantly improves the ability to cough up and clear secretions from the lungs.\nAdditionally, SODICHLOR 3% helps restore the normal salt and water balance on airway surfaces, which is particularly important in conditions like cystic fibrosis where this balance is naturally disrupted. The solution also stimulates ciliary beat frequency, enhancing the natural cleaning mechanism of the respiratory tract. By improving mucociliary clearance, SODICHLOR 3% helps reduce the bacterial burden in the airways, potentially decreasing the frequency of respiratory infections and exacerbations.\nPrimary Uses and Applications\nSODICHLOR 3% is prescribed for various respiratory conditions where enhanced mucus clearance is clinically beneficial:\nCystic Fibrosis Management: Perhaps the most well-established use, SODICHLOR 3% has become a cornerstone therapy for patients with cystic fibrosis. Regular use helps thin the abnormally thick mucus characteristic of this genetic condition, improving lung function and quality of life while reducing the risk of pulmonary exacerbations.\nChronic Obstructive Pulmonary Disease: For COPD patients who struggle with excessive mucus production and poor clearance, SODICHLOR 3% provides relief by facilitating easier expectoration and improving breathing comfort.\nBronchiectasis: This condition, characterized by permanently damaged and widened airways that trap mucus, benefits significantly from hypertonic saline therapy. SODICHLOR 3% helps clear the pooled secretions that contribute to recurrent infections.\nPost-Operative Respiratory Care: Following certain surgical procedures, particularly thoracic surgeries, SODICHLOR 3% may be used to prevent mucus plugging and atelectasis by maintaining adequate airway hydration.\nSputum Induction: In diagnostic settings, SODICHLOR 3% can be used to induce sputum production for laboratory testing when patients cannot spontaneously produce adequate samples.\nKey Benefits of SODICHLOR 3%\nThe therapeutic advantages of SODICHLOR 3% extend across multiple dimensions of respiratory health:\nEnhanced Mucus Clearance: The primary benefit is the dramatic improvement in the ability to clear thick, sticky mucus from the airways. Patients often report easier breathing and more productive coughing within minutes of treatment.\nImproved Lung Function: Clinical studies have demonstrated that regular use of hypertonic saline solutions like SODICHLOR 3% can lead to measurable improvements in pulmonary function tests, including forced expiratory volume (FEV1) and forced vital capacity (FVC).\nReduced Infection Frequency: By promoting better mucus clearance and reducing bacterial colonization in the airways, SODICHLOR 3% may help decrease the frequency of respiratory infections and disease exacerbations, leading to fewer hospitalizations.\nNon-Antibiotic Therapy: In an era of increasing antibiotic resistance, SODICHLOR 3% offers a mechanical rather than chemical approach to managing respiratory symptoms, making it a valuable addition to any treatment regimen without contributing to resistance patterns.\nCost-Effective Treatment: Compared to many specialized respiratory medications, SODICHLOR 3% represents a relatively affordable therapeutic option that can be used long-term without prohibitive expense.\nQuality of Life Enhancement: Patients using SODICHLOR 3% regularly often report significant improvements in their daily activities, exercise tolerance, and overall sense of well-being due to easier breathing and reduced respiratory distress.\nCompatibility with Other Treatments: SODICHLOR 3% can be safely used alongside other respiratory medications, including bronchodilators, corticosteroids, and antibiotics, as part of a comprehensive treatment plan.\nPotential Side Effects and Considerations\nWhile SODICHLOR 3% is generally well-tolerated, patients should be aware of potential side effects:\nCommon Side Effects: The most frequently reported adverse effects include throat irritation, coughing (especially initially), unpleasant taste, and mild wheezing or chest tightness. These effects are typically transient and often diminish with continued use as the body adapts to the therapy.\nBronchospasm: Some patients, particularly those with hyperreactive airways or asthma, may experience bronchospasm (sudden narrowing of the airways) during or after treatment. This is why healthcare providers often recommend using a bronchodilator before SODICHLOR 3% administration.\nTemporary Oxygen Desaturation: In some cases, especially in patients with severe lung disease, temporary decreases in blood oxygen levels may occur immediately after treatment, though levels typically return to baseline within 30 minutes.\nNasal Congestion and Rhinorrhea: Some patients may experience nasal stuffiness or runny nose following inhalation therapy.\nLess Common Effects: Headache, nausea, dizziness, or voice changes may occasionally occur but are generally mild and self-limiting.\nPatients with certain conditions such as uncontrolled hypertension, severe electrolyte imbalances, or recent hemoptysis should use SODICHLOR 3% only under close medical supervision. As with any medical treatment, it's essential to discuss your complete medical history with your healthcare provider before beginning therapy.\nConclusion\nSODICHLOR 3% represents a scientifically sound, clinically proven approach to managing respiratory conditions complicated by thick mucus secretions. Its mechanism of action—leveraging osmotic principles to hydrate and mobilize airway secretions—addresses a fundamental problem faced by millions of patients with chronic respiratory diseases. The substantial body of evidence supporting its efficacy, combined with its favorable safety profile and cost-effectiveness, makes SODICHLOR 3% an indispensable component of modern respiratory care.",
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"name": "Magnesium glycine complex and vitamin d3 Tablet",
"description": "FABRICAL D3 represents a breakthrough in nutritional supplementation, combining the superior bioavailability of magnesium glycinate complex with the essential benefits of vitamin D3 (cholecalciferol). This scientifically formulated supplement addresses two of the most common nutritional deficiencies affecting modern populations, offering a comprehensive solution for individuals seeking to optimize their mineral and vitamin intake for overall health and wellness.\nThe unique formulation of FABRICAL D3 harnesses the synergistic relationship between magnesium and vitamin D3, two nutrients that work in tandem to support numerous physiological processes. While magnesium glycinate provides highly absorbable magnesium bound to the amino acid glycine, vitamin D3 delivers the most bioactive form of vitamin D, ensuring maximum therapeutic benefit with minimal gastrointestinal discomfort.\nUnderstanding the Components\nMagnesium Glycinate Complex\nMagnesium glycinate is widely regarded as one of the most bioavailable forms of magnesium supplementation. Unlike other magnesium compounds that may cause digestive upset, the glycinate form is chelated with glycine, an amino acid that facilitates gentle absorption and enhances tolerability. This molecular structure allows magnesium to pass through the intestinal wall more efficiently, delivering therapeutic levels of this essential mineral to tissues throughout the body.\nMagnesium participates in over 300 enzymatic reactions within the human body, making it indispensable for energy production, protein synthesis, muscle function, and nervous system regulation. The glycinate form specifically offers additional calming benefits through glycine's natural ability to support neurotransmitter balance and promote relaxation.\nVitamin D3 (Cholecalciferol)\nVitamin D3 is the biologically active form of vitamin D that the body naturally produces when skin is exposed to sunlight. FABRICAL D3 provides supplemental cholecalciferol to compensate for inadequate sun exposure, dietary insufficiency, or increased physiological demands. Vitamin D3 functions more as a hormone than a traditional vitamin, influencing gene expression and regulating calcium absorption, immune function, and cellular health throughout the body.\nPrimary Uses and Applications\nFABRICAL D3 is designed for individuals experiencing or at risk of magnesium and vitamin D deficiency. Common scenarios warranting supplementation include:\nBone Health Support: The combination supports optimal bone density by facilitating calcium absorption and utilization. Magnesium activates vitamin D, while vitamin D enhances calcium absorption—creating a powerful triad for skeletal integrity.\nMuscle Function and Recovery: Athletes, active individuals, and those experiencing muscle cramps or tension benefit from magnesium's role in muscle contraction and relaxation, while vitamin D supports muscle strength and recovery.\nMood and Cognitive Support: Both nutrients influence neurotransmitter production and brain function. Magnesium glycinate's calming properties combined with vitamin D's mood-regulating effects make FABRICAL D3 valuable for emotional wellness.\nSleep Quality Enhancement: The glycinate component promotes relaxation and may improve sleep quality, while adequate vitamin D levels correlate with better sleep patterns.\nImmune System Fortification: Vitamin D3 plays a critical role in immune cell function, while magnesium supports the immune response through various enzymatic pathways.\nCardiovascular Health: Magnesium supports healthy blood pressure and vascular function, while vitamin D contributes to cardiovascular system regulation.\nEnergy Production: Magnesium is essential for ATP synthesis, the body's primary energy currency, helping combat fatigue and support metabolic efficiency.\nKey Benefits of FABRICAL D3\nEnhanced Bioavailability\nThe magnesium glycinate complex offers superior absorption compared to conventional magnesium oxide or citrate forms, ensuring therapeutic levels reach target tissues without gastrointestinal distress.\nDual-Action Formula\nBy addressing two prevalent nutritional deficiencies simultaneously, FABRICAL D3 provides comprehensive nutritional support in a single convenient tablet.\nGentle on Digestion\nThe glycinate form minimizes the laxative effect commonly associated with magnesium supplementation, making it suitable for individuals with sensitive digestive systems.\nSynergistic Nutrient Interaction\nMagnesium activates vitamin D, while vitamin D enhances magnesium absorption—creating a mutually beneficial relationship that maximizes the efficacy of both nutrients.\nNervous System Support\nThe combination promotes neurological health, supporting stress response, cognitive function, and overall mental clarity.\nBone Density Optimization\nTogether, these nutrients create an optimal environment for calcium utilization, supporting skeletal strength and reducing fracture risk.\nImproved Muscle Function\nThe formula addresses muscle cramping, tension, and weakness while supporting post-exercise recovery and physical performance.\nConvenient Dosing\nSingle-tablet formulation simplifies supplementation routines, improving compliance and consistency.\nPotential Side Effects and Considerations\nWhile FABRICAL D3 is generally well-tolerated, some individuals may experience side effects, particularly when beginning supplementation or taking doses exceeding recommended guidelines:\nMagnesium-Related Effects:\n\nMild digestive upset, though significantly less common with glycinate forms\nDiarrhea if dosage exceeds individual tolerance (typically above 400-500mg elemental magnesium)\nNausea in sensitive individuals\n\nVitamin D3-Related Effects:\n\nHypercalcemia (elevated blood calcium) with excessive long-term supplementation\nNausea or vomiting with very high doses\nKidney stone formation in susceptible individuals taking excessive amounts\nFatigue or weakness if overdosed\n\nGeneral Considerations:\nIndividuals with kidney disease should consult healthcare providers before use, as magnesium excretion may be impaired. Those taking medications including antibiotics, bisphosphonates, diuretics, or heart medications should discuss potential interactions with their physician. Vitamin D supplementation should be monitored in individuals with hyperparathyroidism, sarcoidosis, or other conditions affecting calcium metabolism.\nRecommended Usage\nFor optimal results, take FABRICAL D3 as directed by healthcare professionals or according to package instructions. Generally, supplementation is most effective when taken with food containing healthy fats, which enhance vitamin D3 absorption. Consistency is crucial—daily supplementation allows the body to maintain steady nutrient levels and experience cumulative benefits over time.\nIndividuals should consider periodic blood testing to monitor vitamin D and magnesium status, ensuring supplementation achieves therapeutic ranges without exceeding safe upper limits. Healthcare providers can adjust dosing based on individual biochemistry, lifestyle factors, and health objectives.\nConclusion\nFABRICAL D3 represents an intelligently designed nutritional supplement that addresses two fundamental nutritional gaps affecting millions worldwide. By combining highly bioavailable magnesium glycinate with vitamin D3, this formulation delivers comprehensive support for bone health, muscle function, immune system performance, mood regulation, and overall vitality.\nThe scientific synergy between these nutrients—where each enhances the other's absorption and function—makes FABRICAL D3 more than a simple combination product. It's a thoughtfully engineered solution that recognizes how nutrients work together within the complex systems of human physiology.",
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"name": "Cinnarizine and Domperidone Tablets ",
"description": "CLANARIZINE DOM represents an advanced pharmaceutical combination that brings together two potent therapeutic agents—Cinnarizine and Domperidone—in a single convenient tablet formulation. This innovative combination medication addresses multiple aspects of vestibular disorders, motion sickness, and associated nausea and vomiting, providing comprehensive relief for patients suffering from these debilitating conditions. Manufactured under stringent quality control standards, CLANARIZINE DOM offers a synergistic approach to managing symptoms that significantly impact quality of life and daily functioning.The combination of Cinnarizine and Domperidone in CLANARIZINE DOM is based on sound pharmacological principles. While Cinnarizine works primarily on the vestibular system to reduce dizziness and vertigo, Domperidone acts as an effective antiemetic to control nausea and vomiting. Together, these two active ingredients provide more comprehensive symptom control than either agent alone, making CLANARIZINE DOM an excellent choice for patients experiencing vestibular disturbances accompanied by gastrointestinal symptoms.This combination therapy is particularly valuable because vertigo, dizziness, and motion sickness are frequently accompanied by nausea and vomiting. Patients suffering from these conditions often find that addressing only one aspect of their symptoms provides insufficient relief. CLANARIZINE DOM's dual-action formula tackles both the underlying vestibular dysfunction and the accompanying gastrointestinal distress, offering patients a more complete therapeutic solution that improves both comfort and functional capacity.Understanding the Active IngredientsCinnarizine is a calcium channel blocker with specific antihistaminic and vestibular suppressant properties. Unlike systemic calcium channel blockers used for cardiovascular conditions, Cinnarizine selectively acts on the blood vessels in the inner ear and brain, improving blood flow to these areas. This enhanced circulation helps reduce the frequency and severity of vertigo attacks while also preventing motion sickness. Cinnarizine also possesses mild antihistaminic effects that contribute to its anti-nausea properties, though this is not its primary mechanism of action.The medication works by blocking calcium channels in the vestibular system, which helps stabilize the sensory organs responsible for balance. By reducing the excessive stimulation of the vestibular apparatus, Cinnarizine decreases the sensation of spinning or imbalance that characterizes vertigo. Additionally, its vasodilatory effects improve microcirculation in the inner ear, which can be beneficial for conditions where reduced blood flow contributes to symptoms.Domperidone is a peripheral dopamine antagonist that acts primarily as a prokinetic and antiemetic agent. Unlike some antiemetic medications that cross the blood-brain barrier and cause sedation or extrapyramidal side effects, Domperidone works predominantly in the peripheral nervous system. It blocks dopamine receptors in the chemoreceptor trigger zone (CTZ) located outside the blood-brain barrier, effectively preventing nausea and vomiting without causing significant central nervous system effects.Domperidone also enhances gastrointestinal motility by promoting coordinated contractions of the stomach and upper small intestine. This prokinetic effect helps empty the stomach more efficiently, reducing feelings of fullness, bloating, and discomfort that often accompany vestibular disorders. By accelerating gastric emptying, Domperidone also reduces the likelihood of gastroesophageal reflux, which can exacerbate nausea in some patients.The combination of these two medications in CLANARIZINE DOM creates a complementary therapeutic effect. While Cinnarizine addresses the vestibular component of dizziness and vertigo, Domperidone manages the gastrointestinal symptoms that frequently accompany these conditions. This dual approach provides more comprehensive symptom relief and improves overall treatment outcomes compared to monotherapy with either agent alone.Clinical Applications and UsesCLANARIZINE DOM is indicated for a wide range of conditions characterized by vertigo, dizziness, and associated nausea. Understanding these clinical applications helps healthcare providers select appropriate candidates for this combination therapy.Vestibular Disorders: The primary indication for CLANARIZINE DOM includes various vestibular disorders that cause vertigo and imbalance. These conditions include Ménière's disease, benign paroxysmal positional vertigo (BPPV), vestibular neuritis, and labyrinthitis. Patients with these disorders experience episodes of spinning sensation, loss of balance, and often severe nausea. CLANARIZINE DOM helps reduce the frequency and intensity of vertigo attacks while controlling the accompanying gastrointestinal symptoms.Motion Sickness: CLANARIZINE DOM is highly effective for preventing and treating motion sickness, whether related to travel by car, boat, airplane, or amusement park rides. The medication can be taken prophylactically before travel or at the onset of symptoms. The combination is particularly useful for individuals who experience severe nausea and vomiting with motion sickness, as Domperidone provides powerful antiemetic effects that complement Cinnarizine's anti-motion-sickness properties.Migraine-Associated Vertigo: Many patients with migraines experience vestibular symptoms, including dizziness, vertigo, and motion sensitivity, either during migraine attacks or as independent episodes. CLANARIZINE DOM can help manage these vestibular manifestations of migraine, reducing both the vertigo and the nausea that often accompany migraine headaches.Post-Concussion Syndrome: Following head injuries, some patients develop persistent dizziness, balance problems, and nausea as part of post-concussion syndrome. CLANARIZINE DOM may provide symptomatic relief for these patients during their recovery period, though it should be used as part of a comprehensive treatment approach that includes rest, gradual return to activities, and vestibular rehabilitation when appropriate.Cerebrovascular Insufficiency: In older adults with reduced blood flow to the brain, symptoms such as dizziness, vertigo, tinnitus (ringing in the ears), and cognitive difficulties may develop. Cinnarizine's vasodilatory properties can improve cerebral circulation, potentially reducing these symptoms. The addition of Domperidone helps manage any associated nausea.Radiation-Induced or Chemotherapy-Induced Nausea: While not a primary indication, some healthcare providers use CLANARIZINE DOM as adjunctive therapy for patients undergoing cancer treatment who experience both nausea and dizziness. Domperidone's strong antiemetic properties are particularly valuable in this context.Key Benefits of CLANARIZINE DOMThe unique combination of Cinnarizine and Domperidone in CLANARIZINE DOM offers numerous advantages that make it a preferred choice for managing vestibular disorders and associated symptoms.Comprehensive Symptom Control: The primary benefit of CLANARIZINE DOM is its ability to address multiple symptoms simultaneously. Rather than requiring patients to take separate medications for vertigo and nausea, this combination provides unified treatment in a single tablet. This comprehensive approach improves symptom control across the full spectrum of vestibular disorder manifestations, from the spinning sensation to the gastrointestinal distress that often accompanies it.Improved Patient Compliance: Taking multiple medications can be burdensome, particularly for patients who feel dizzy or nauseated. CLANARIZINE DOM simplifies the treatment regimen by combining two medications in one tablet, making it easier for patients to adhere to their prescribed therapy. Better compliance translates to better outcomes, as consistent medication use is essential for managing chronic vestibular conditions.Synergistic Therapeutic Effects: The combination of Cinnarizine and Domperidone creates synergistic effects that enhance overall efficacy. While Cinnarizine reduces vestibular stimulation and improves inner ear blood flow, Domperidone prevents nausea and promotes gastric emptying. This dual action addresses both the cause and consequences of vestibular dysfunction, providing more complete relief than either medication alone.Reduced Central Nervous System Side Effects: Because Domperidone works primarily in the peripheral nervous system rather than crossing the blood-brain barrier extensively, CLANARIZINE DOM causes less sedation and fewer cognitive effects compared to some alternative antiemetic medications. This allows patients to maintain better alertness and function during treatment, which is particularly important for those who need to continue working or performing daily activities.Enhanced Quality of Life: Vertigo and chronic dizziness significantly impair quality of life, limiting mobility, social interactions, and occupational functioning. The nausea and vomiting that accompany these conditions add another layer of disability. By effectively controlling both vestibular and gastrointestinal symptoms, CLANARIZINE DOM helps restore patients' ability to engage in normal activities, improving overall life satisfaction and functional independence.Fast Onset of Action: CLANARIZINE DOM provides relatively rapid symptom relief, with many patients experiencing improvement within 30 minutes to 2 hours after taking the medication. This quick onset is particularly valuable for acute episodes of vertigo or when taking the medication prophylactically before situations that might trigger motion sickness.Suitable for Long-Term Use: For patients with chronic vestibular disorders requiring ongoing treatment, CLANARIZINE DOM is generally safe for extended use when properly monitored by a healthcare provider. The medication maintains its effectiveness over time without significant tolerance development, making it suitable for long-term symptom management.Improved Gastric Emptying: The prokinetic effects of Domperidone benefit not only nausea but also other gastrointestinal symptoms such as early satiety, bloating, and upper abdominal discomfort. Patients with vestibular disorders often develop gastroparesis or delayed gastric emptying secondary to their condition, and Domperidone addresses this issue effectively.Vascular Benefits: Cinnarizine's ability to improve blood flow to the inner ear and brain provides additional benefits beyond symptom control. Enhanced microcirculation may support healing and recovery in conditions where vascular insufficiency contributes to vestibular dysfunction.Side Effects and Safety ConsiderationsLike all medications, CLANARIZINE DOM can cause side effects, though not everyone experiences them. Understanding potential adverse effects helps patients recognize when to seek medical attention and allows healthcare providers to monitor therapy appropriately.Common Side Effects:The most frequently reported side effect of CLANARIZINE DOM is drowsiness or sedation, occurring in approximately 10-20% of patients. This effect is primarily attributable to Cinnarizine's antihistaminic properties. Patients should avoid driving or operating machinery until they know how the medication affects them. Taking the medication at bedtime can minimize daytime drowsiness for some patients.Dry mouth is another common side effect, affecting roughly 10-15% of patients. This occurs due to anticholinergic effects and can be managed by sipping water frequently, chewing sugar-free gum, or using saliva substitutes if severe. Maintaining good oral hygiene is important to prevent dental problems associated with reduced saliva production.Mild gastrointestinal symptoms, including constipation, abdominal discomfort, or changes in bowel habits, may occur. While Domperidone promotes gastric emptying, it can occasionally alter bowel motility. These effects are usually mild and resolve with continued use or dose adjustment.",
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"name": "Ivabradine 5mg",
"description": "Introduction\n\nA healthy heart rhythm is essential for maintaining energy, stamina, and overall well-being. When the heart beats too fast at rest, it can place unnecessary strain on the heart muscle, reduce blood supply to vital organs, and increase the risk of long-term cardiovascular complications. Conditions such as chronic stable angina and certain types of heart failure are often associated with an elevated resting heart rate, which can worsen symptoms and limit daily activities.\n\nIVADRIVE 5, containing Ivabradine 5 mg, is a specialized heart-rate–lowering medication designed to help control heart rate without reducing blood pressure or weakening heart contraction. Unlike many traditional cardiac drugs, IVADRIVE 5 works selectively on the heart’s natural pacemaker, helping the heart beat more slowly and efficiently. This targeted approach allows patients to experience better symptom control, improved exercise tolerance, and enhanced quality of life.\n\nComposition\n\nActive Ingredient: Ivabradine 5 mg\n\nBrand Name: IVADRIVE 5\n\nDosage Form: Oral Tablet\n\nIvabradine belongs to a unique class of medications known as selective heart rate–reducing agents.\n\nHow IVADRIVE 5 Works\n\nThe heart’s rhythm is controlled by a natural pacemaker called the sinoatrial (SA) node. Ivabradine acts specifically on the “If” (funny) channels in the SA node, which are responsible for regulating heart rate.\n\nBy selectively inhibiting these channels:\n\nThe heart rate slows down\n\nOxygen demand of the heart is reduced\n\nBlood flow to the heart muscle improves\n\nCardiac efficiency increases\n\nImportantly, IVADRIVE 5 lowers heart rate without affecting blood pressure or heart muscle strength, making it especially suitable for patients who cannot tolerate beta-blockers or require additional heart rate control.\n\nUses of IVADRIVE 5\n1. Chronic Stable Angina\n\nIVADRIVE 5 is widely used to treat chronic stable angina in patients with normal heart rhythm but elevated resting heart rate. By slowing the heart rate, it reduces chest pain episodes and improves exercise tolerance.\n\n2. Chronic Heart Failure\n\nIt is prescribed in selected patients with chronic heart failure to reduce hospitalizations and improve heart function when heart rate remains high despite standard therapy.\n\n3. Heart Rate Control\n\nIVADRIVE 5 is beneficial for patients who require heart rate reduction but cannot tolerate traditional heart-rate-lowering drugs.\n\nKey Benefits of IVADRIVE 5\n1. Effective Heart Rate Reduction\n\nIVADRIVE 5 specifically lowers resting heart rate, helping the heart work more efficiently and reducing strain on the heart muscle.\n\n2. Improves Exercise Capacity\n\nPatients often notice improved stamina and reduced fatigue during physical activity due to better oxygen delivery.\n\n3. Reduces Angina Attacks\n\nBy decreasing oxygen demand, IVADRIVE 5 helps lower the frequency and severity of chest pain episodes.\n\n4. Preserves Blood Pressure\n\nUnlike many cardiac medicines, it does not significantly lower blood pressure, making it suitable for patients with normal or low blood pressure.\n\n5. Supports Long-Term Heart Health\n\nConsistent use may help reduce disease progression and hospitalization risk in heart failure patients.\n\n6. Well-Tolerated Option\n\nIVADRIVE 5 is generally well tolerated and can be used alone or in combination with other cardiovascular medications under medical supervision.\n\nDosage and Administration\n\nThe usual starting dose is Ivabradine 5 mg, taken twice daily.\n\nTablets should be taken with meals for optimal absorption.\n\nDose adjustments may be made based on heart rate response and tolerance.\n\nImportant: Always follow your doctor’s instructions and do not stop or change the dose without medical advice.\n\nPossible Side Effects of IVADRIVE 5\n\nWhile IVADRIVE 5 is generally safe when used as prescribed, some patients may experience side effects.\n\nCommon Side Effects\n\nSlow heart rate (bradycardia)\n\nHeadache\n\nDizziness\n\nFatigue\n\nVisual Disturbances\n\nTemporary brightness or light flashes (phosphenes)\n\nBlurred vision in low-light conditions\nThese effects are usually mild and reversible.\n\nLess Common Side Effects\n\nNausea\n\nLow blood pressure symptoms\n\nIrregular heartbeat sensations\n\nRare Side Effects\n\nSevere bradycardia\n\nHeart rhythm disturbances\n\nPatients should report any persistent or severe symptoms to their healthcare provider promptly.\n\nPrecautions and Warnings\n\nHeart Rhythm Disorders: Not recommended in patients with certain arrhythmias.\n\nLow Heart Rate: Should not be used if resting heart rate is already very low.\n\nPregnancy and Breastfeeding: Use only if clearly advised by a doctor.\n\nLiver Disorders: Caution is advised in patients with liver impairment.\n\nDrug Interactions: Inform your doctor about all medications, including antifungals, antibiotics, and herbal supplements.\n\nWho Should Avoid IVADRIVE 5?\n\nPatients with severe bradycardia\n\nIndividuals with acute heart failure\n\nPatients with pacemaker dependency\n\nThose allergic to Ivabradine\n\nStorage Instructions\n\nStore below 25°C\n\nProtect from moisture and direct sunlight\n\nKeep out of reach of children\n\nDo not use after expiry date\n\nConclusion\n\nIVADRIVE 5 (Ivabradine 5 mg) offers a focused and effective solution for managing elevated heart rate in patients with chronic stable angina and selected cases of heart failure. By selectively acting on the heart’s natural pacemaker, it delivers targeted heart rate control without compromising blood pressure or cardiac strength.",
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"name": "coenzyme q10 tablets india",
"description": "Coenzyme Q10, commonly referred to as CoQ10, is a vital antioxidant naturally present in the human body. It plays a significant role in energy production and cellular protection. CO ADD Q10 Tablets, a high-quality formulation by Steris Healthcare, is designed to help maintain optimal CoQ10 levels in the body, supporting energy metabolism, cardiovascular health, and overall wellness.\n\nCoQ10 is particularly essential for individuals with low energy, aging-related oxidative stress, or those on statin medications, as these conditions can reduce the natural levels of CoQ10 in the body. CO ADD Q10 Tablets offer a convenient way to replenish this critical nutrient and promote a healthier, more active lifestyle.\n\nHow CO ADD Q10 Tablet Works\n\nThe primary function of CoQ10 is in the production of adenosine triphosphate (ATP), the energy currency of our cells. ATP is crucial for all bodily functions, including muscle contraction, nerve transmission, and organ performance. CO ADD Q10 enhances the efficiency of the mitochondria—the powerhouse of the cells—by participating in the electron transport chain, which is necessary for ATP generation.\n\nIn addition to its role in energy production, CoQ10 acts as a potent antioxidant, neutralizing harmful free radicals that cause oxidative damage to cells and tissues. By reducing oxidative stress, CO ADD Q10 supports cardiovascular health, slows the aging process, and protects against chronic diseases.\n\nComposition\n\nEach CO ADD Q10 Tablet contains:\n\nCoenzyme Q10 (CoQ10) – 100 mg\n\nExcipients – q.s.\n\nThis composition ensures a clinically effective dose of CoQ10, formulated for maximum absorption and bioavailability in the body.\n\nUses of CO ADD Q10 Tablets\n\nCO ADD Q10 Tablets are recommended for a variety of health purposes:\n\nSupports Heart Health—CoQ10 strengthens cardiac muscle, supports normal blood pressure, and improves overall heart function.\n\nEnhances Energy Levels—By boosting ATP production, CO ADD Q10 reduces fatigue and increases stamina for daily activities.\n\nPowerful Antioxidant Protection – Protects cells from oxidative damage, promoting healthy aging and cellular wellness.\n\nStatin Support – Patients taking statin medications often have lower CoQ10 levels; supplementation helps restore these levels and reduce side effects like muscle pain.\n\nOverall Wellness – Supports immune function, mental clarity, and metabolic efficiency.\n\nKey Benefits of CO ADD Q10 Tablets\n\nCardiovascular Health: Improves heart function and maintains healthy blood pressure levels.\n\nEnergy & Stamina: Reduces fatigue and enhances physical and mental performance.\n\nAntioxidant Protection: Fights oxidative stress, protecting against cellular damage and age-related changes.\n\nBrain Function Support: CoQ10 contributes to neuroprotection, supporting focus, memory, and cognitive function.\n\nSupports Statin Therapy: Helps prevent statin-induced myopathy by replenishing depleted CoQ10 levels.\n\nSide Effects of CO ADD Q10 Tablets\n\nCO ADD Q10 Tablets are generally well-tolerated. However, some individuals may experience mild side effects, which are usually temporary.\n\nCommon Side Effects\n\nNausea or upset stomach\n\nDiarrhea or mild gastrointestinal discomfort\n\nHeadache\n\nDizziness\n\nSerious Side Effects (Rare)\n\nAllergic reactions such as rash, itching, or swelling\n\nRapid heartbeat or palpitations in sensitive individuals\n\nIf any severe symptoms occur, it is advised to discontinue use and consult a healthcare professional immediately.\n\nDosage Guidelines\n\nFor adults, the recommended dose is generally:\n\n100 mg to 200 mg per day\n\nTake the tablet with meals to improve absorption\n\nAvoid taking on an empty stomach to reduce gastrointestinal discomfort\n\nAlways consult a physician before starting CO ADD Q10 Tablets, especially if you are on medications or have underlying health conditions.\n\nPrecautions & Warnings\n\nConsult a doctor before use during pregnancy or breastfeeding.\n\nInform your healthcare provider if you are on blood thinners or heart medications.\n\nStore in a cool, dry place away from direct sunlight.\n\nDo not exceed the recommended dosage.\n\nKeep out of reach of children.\n\nMechanism of Action\n\nCoenzyme Q10 functions as a cofactor in the mitochondrial electron transport chain, facilitating electron transfer from complex I and II to complex III, which is critical for ATP synthesis. By enhancing mitochondrial function, CO ADD Q10 improves energy production at the cellular level and reduces oxidative stress by neutralizing free radicals.\n\nThis dual action—boosting energy and protecting cells—makes CO ADD Q10 an essential supplement for individuals seeking overall wellness and longevity.\n\nClinical Evidence & Efficacy\n\nScientific studies support the use of CoQ10 in various health areas:\n\nImproves cardiac output and ejection fraction in heart failure patients\n\nReduces fatigue and enhances exercise performance\n\nLowers oxidative stress markers, protecting against chronic diseases\n\nSupports patients on statin therapy by replenishing depleted CoQ10 levels\n\nThese clinical findings validate CO ADD Q10 Tablets as a reliable choice for cardiovascular support, energy enhancement, and antioxidant protection.\n\nFrequently Asked Questions\n\nQ1. How long does it take to see benefits?\nA1. Noticeable improvements in energy and stamina can appear within 4–8 weeks of regular use.\n\nQ2. Can CO ADD Q10 Tablets be taken with other medications?\nA2. Generally yes, but consult a healthcare professional if you are taking blood thinners or heart medications.\n\nQ3. Are CO ADD Q10 Tablets suitable for elderly individuals?\nA3. Yes, they are safe for older adults and may help support energy levels and cardiovascular health.\n\nQ4. Can diabetics take CO ADD Q10 Tablets?\nA4. Yes, but consultation with a healthcare professional is recommended.\n\nConclusion\n\nCO ADD Q10 Tablets by Steris Healthcare are a scientifically formulated Coenzyme Q10 supplement designed to support heart health, boost energy, and protect cells from oxidative damage. With its clinically validated composition, high absorption, and proven benefits, CO ADD Q10 is a trusted choice for anyone looking to maintain vitality and overall wellness.\n\nWhether you are seeking improved energy levels, cardiovascular support, or enhanced antioxidant protection, CO ADD Q10 Tablets provide a safe and effective solution for long-term health and well-being.",
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"name": "Mirtazapine 30mg",
"description": "MIRTAZPRIME 30 is a pharmaceutical formulation containing Mirtazapine 30mg as per Indian Pharmacopoeia (IP) standards. This prescription medication belongs to a class of drugs known as tetracyclic antidepressants and represents an advanced therapeutic option for individuals struggling with major depressive disorder and related mental health conditions. Manufactured under stringent quality control measures, MIRTAZPRIME 30 offers patients a reliable and effective solution for managing depression while also addressing associated symptoms such as insomnia and anxiety.\nMirtazapine, the active pharmaceutical ingredient in MIRTAZPRIME 30, works through a unique dual mechanism that distinguishes it from other antidepressants. Unlike selective serotonin reuptake inhibitors (SSRIs), mirtazapine enhances the release of both norepinephrine and serotonin in the brain by blocking specific receptors. This innovative approach not only helps alleviate depressive symptoms but also provides sedative effects that can be particularly beneficial for patients experiencing sleep disturbances alongside depression.\nTherapeutic Uses and Applications\nMIRTAZPRIME 30 is primarily indicated for the treatment of major depressive disorder (MDD), a serious mental health condition characterized by persistent feelings of sadness, hopelessness, and loss of interest in daily activities. The medication has demonstrated significant efficacy in clinical trials, showing improvement in mood, energy levels, and overall quality of life for patients suffering from depression.\nBeyond its primary indication, healthcare providers may prescribe MIRTAZPRIME 30 for various off-label uses based on clinical judgment and patient needs. The medication has shown promise in managing generalized anxiety disorder, where excessive worry and tension interfere with daily functioning. Its sedative properties make it particularly valuable for patients experiencing insomnia related to depression or anxiety, as it can help restore healthy sleep patterns without the need for additional sleep medications.\nThe 30mg dosage strength represents a therapeutic level commonly prescribed for maintenance treatment after initial dose titration. Patients typically begin with lower doses and gradually increase to 30mg as their body adjusts to the medication and their symptoms require more robust management. This dosage provides an optimal balance between therapeutic efficacy and side effect management for many individuals.\nMIRTAZPRIME 30 may also be considered for patients who have not responded adequately to other antidepressant therapies, offering an alternative mechanism of action that can break through treatment-resistant depression. Additionally, its appetite-stimulating effects can be beneficial for patients experiencing significant weight loss due to depression or other medical conditions.\nKey Benefits and Therapeutic Advantages\nThe benefits of MIRTAZPRIME 30 extend beyond simple symptom relief, offering patients a multifaceted approach to mental health recovery. One of the most significant advantages is its relatively rapid onset of action compared to many other antidepressants. While most SSRIs require several weeks to demonstrate meaningful clinical improvement, patients taking mirtazapine often experience some relief from symptoms within one to two weeks, with continued improvement over subsequent weeks.\nThe dual neurotransmitter action of MIRTAZPRIME 30 provides comprehensive coverage of depressive symptoms. By enhancing both serotonergic and noradrenergic neurotransmission, the medication addresses the complex neurochemical imbalances underlying depression more thoroughly than single-mechanism antidepressants. This broader action can result in more complete symptom resolution and better overall outcomes.\nSleep improvement represents another crucial benefit of MIRTAZPRIME 30. The medication's sedative properties, particularly pronounced at lower doses, help patients fall asleep faster and enjoy more restorative sleep throughout the night. This is especially valuable since sleep disturbances are both a symptom and an exacerbating factor in depression. Better sleep quality contributes to improved daytime functioning, energy levels, and emotional regulation.\nUnlike many antidepressants that commonly cause sexual dysfunction, MIRTAZPRIME 30 has a relatively favorable profile in this regard. The medication is less likely to interfere with sexual function, making it an attractive option for patients who have experienced these troublesome side effects with other antidepressants. This characteristic can significantly improve treatment adherence and quality of life.\nThe appetite-stimulating effect, while considered a side effect by some, can be therapeutically beneficial for patients experiencing significant weight loss or poor appetite due to depression. MIRTAZPRIME 30 can help restore healthy eating patterns and reverse the physical decline that often accompanies severe depressive episodes.\nFurthermore, MIRTAZPRIME 30 does not typically cause the gastrointestinal side effects commonly associated with SSRI antidepressants, such as nausea, diarrhea, or stomach upset. This improved gastrointestinal tolerability enhances patient comfort and compliance with treatment regimens.\nPotential Side Effects and Safety Considerations\nWhile MIRTAZPRIME 30 offers numerous therapeutic benefits, patients should be aware of potential side effects that may occur during treatment. Understanding these effects helps patients make informed decisions and enables early identification of any concerning symptoms requiring medical attention.\nThe most commonly reported side effect is drowsiness or sedation, particularly during the initial weeks of treatment. This effect is typically most pronounced during the first few hours after taking the medication, which is why it's generally recommended for evening administration. Patients should exercise caution when driving, operating machinery, or engaging in activities requiring alertness until they understand how the medication affects them personally.\nIncreased appetite and weight gain represent another frequent side effect of MIRTAZPRIME 30. While beneficial for some patients, others may find this effect undesirable. Weight gain typically ranges from moderate to significant and appears to be dose-related. Patients concerned about weight should discuss dietary strategies and exercise plans with their healthcare provider.\nDry mouth is a common anticholinergic side effect that can cause discomfort but is generally manageable through increased fluid intake, sugar-free gum or candy, and good oral hygiene practices. Some patients may also experience dizziness, particularly when standing up quickly, due to the medication's effects on blood pressure regulation.\nConstipation may occur in some patients and can usually be managed through dietary modifications, increased fiber intake, adequate hydration, and regular physical activity. Less commonly, patients might experience confusion, abnormal dreams, or changes in thinking, particularly in older adults who may be more sensitive to the medication's effects.\nSerious side effects, while rare, require immediate medical attention. These include signs of allergic reactions such as rash, itching, swelling, severe dizziness, or difficulty breathing. Agranulocytosis, a dangerous decrease in white blood cells, is an extremely rare but serious complication that manifests as fever, sore throat, or signs of infection. Any unexplained fever or signs of infection should prompt immediate contact with a healthcare provider.\nSerotonin syndrome is another rare but potentially life-threatening condition that can occur when mirtazapine is combined with other medications affecting serotonin levels. Symptoms include agitation, hallucinations, rapid heartbeat, fever, excessive sweating, muscle stiffness, or coordination problems. Patients should inform their healthcare provider about all medications and supplements they are taking to avoid dangerous interactions.\nAbrupt discontinuation of MIRTAZPRIME 30 can lead to withdrawal symptoms, including nausea, anxiety, irritability, and flu-like symptoms. Therefore, any decision to stop the medication should be made in consultation with a healthcare provider who can develop an appropriate tapering schedule.\nImportant Usage Guidelines\nMIRTAZPRIME 30 should always be taken exactly as prescribed by a qualified healthcare professional. The medication is typically administered once daily, preferably in the evening before bedtime due to its sedative effects. Tablets should be swallowed whole with water and can be taken with or without food, though taking them with food may help reduce any stomach upset.\nConsistency in timing is important for maintaining stable blood levels of the medication and optimizing therapeutic effects. Patients should try to take their dose at approximately the same time each evening. If a dose is missed, it should be taken as soon as remembered unless it's close to the time for the next scheduled dose, in which case the missed dose should be skipped rather than doubling up.\nThe full therapeutic benefits of MIRTAZPRIME 30 may take several weeks to manifest. Patients should continue taking the medication as prescribed even if they don't feel immediate improvement. Premature discontinuation is a common reason for treatment failure in depression management.\nRegular follow-up appointments with the prescribing physician are essential for monitoring treatment response, adjusting dosages if necessary, and screening for potential side effects. Patients should maintain open communication with their healthcare team about their symptoms, concerns, and any changes in their condition.\nConclusion\nMIRTAZPRIME 30 represents a valuable therapeutic option in the comprehensive management of major depressive disorder and related conditions. Its unique mechanism of action, combining enhanced noradrenergic and serotonergic neurotransmission with sedative and appetite-stimulating properties, offers distinct advantages for carefully selected patients. The medication's ability to improve both mood symptoms and sleep disturbances makes it particularly useful for patients experiencing depression accompanied by insomnia.\nThe relatively favorable side effect profile, particularly regarding sexual function and gastrointestinal tolerability, enhances patient acceptance and adherence to treatment. While potential side effects such as sedation, increased appetite, and weight gain require monitoring and management, many patients find these effects tolerable compared to the debilitating symptoms of untreated depression.\nSuccess with MIRTAZPRIME 30, as with any antidepressant therapy, depends on proper patient selection, appropriate dosing, regular monitoring, and a comprehensive treatment approach that may include psychotherapy, lifestyle modifications, and social support alongside pharmacological intervention. Patients should work closely with their healthcare providers to optimize treatment outcomes and maintain long-term mental health wellness.\nThe decision to use MIRTAZPRIME 30 should always be made collaboratively between patient and physician, considering individual symptoms, treatment history, coexisting medical conditions, and personal preferences. With proper use under medical supervision, MIRTAZPRIME 30 can be an effective tool in helping patients reclaim their lives from the devastating effects of depression and move toward recovery and renewed well-being.",
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"description": "EPSTATE ED represents an advanced pharmaceutical formulation that combines three powerful therapeutic agents: Pregabalin, Epalrestat, and Methylcobalamin. This innovative triple-combination medication is specifically designed to address the complex pathophysiology of diabetic neuropathy and neuropathic pain conditions. By integrating multiple mechanisms of action, EPSTATE ED offers a comprehensive approach to managing nerve-related complications that significantly impact the quality of life for millions of individuals worldwide.\nThe formulation addresses not only the symptomatic relief of neuropathic pain but also targets the underlying metabolic derangements that contribute to nerve damage progression. This multi-pronged therapeutic strategy makes EPSTATE ED particularly valuable for patients who require more than symptomatic management alone.\nUnderstanding the Active Components\nPregabalin: The Neuropathic Pain Modulator\nPregabalin serves as the cornerstone analgesic component in EPSTATE ED. This anticonvulsant medication works by binding to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. Through this mechanism, Pregabalin reduces the release of excitatory neurotransmitters including glutamate, norepinephrine, and substance P. This reduction in neurotransmitter release effectively dampens the abnormal neural signaling that characterizes neuropathic pain conditions.\nThe molecule demonstrates excellent bioavailability and rapid absorption, allowing patients to experience relief within a relatively short timeframe. Its efficacy in managing various neuropathic pain syndromes has been extensively documented in clinical trials, establishing it as a first-line agent for diabetic peripheral neuropathy, postherpetic neuralgia, and other chronic neuropathic pain conditions.\nEpalrestat: The Aldose Reductase Inhibitor\nEpalrestat represents a unique addition to the formulation, functioning as a selective aldose reductase inhibitor. In diabetic conditions, excess glucose is converted to sorbitol through the polyol pathway, with aldose reductase serving as the rate-limiting enzyme. The accumulation of sorbitol within nerve cells leads to osmotic stress, depletion of myoinositol, and subsequent nerve dysfunction.\nBy inhibiting aldose reductase, Epalrestat prevents this harmful sorbitol accumulation, thereby addressing one of the fundamental metabolic abnormalities responsible for diabetic neuropathy. This disease-modifying approach distinguishes EPSTATE ED from purely symptomatic treatments. Epalrestat has been particularly well-studied in Asian populations and has demonstrated the ability to improve nerve conduction velocities and reduce subjective neuropathic symptoms over time.\nMethylcobalamin: The Neurotropic Vitamin\nMethylcobalamin, the bioactive form of Vitamin B12, completes the therapeutic triad in EPSTATE ED. Unlike cyanocobalamin, which requires conversion in the body, methylcobalamin is immediately available for utilization in crucial biochemical processes. It plays an indispensable role in myelin synthesis, the protective sheath surrounding nerve fibers that enables proper signal transmission.\nThis coenzyme participates in methionine synthesis and is essential for maintaining the structural and functional integrity of neurons. Methylcobalamin also facilitates nerve regeneration and has demonstrated neuroprotective properties in various experimental models. For patients with diabetic neuropathy, who often exhibit Vitamin B12 deficiency (sometimes exacerbated by metformin therapy), supplementation with methylcobalamin addresses both nutritional deficits and supports nerve health at a fundamental level.\nClinical Applications and Uses\nEPSTATE ED is primarily indicated for the comprehensive management of diabetic peripheral neuropathy, a condition affecting approximately 50% of individuals with long-standing diabetes. The symptoms of this condition range from tingling sensations and burning pain to numbness and loss of protective sensation, which can lead to serious complications including foot ulcers and amputations.\nBeyond diabetic neuropathy, EPSTATE ED may be prescribed for various neuropathic pain syndromes where the combination of pain relief, metabolic correction, and nerve support proves beneficial. Patients experiencing chronic nerve pain resulting from metabolic disturbances, nutritional deficiencies, or structural nerve damage may find this combination particularly effective.\nThe medication is typically recommended for adults who have not achieved adequate symptom control with single-agent therapy or who would benefit from the synergistic effects of the three components. Healthcare providers may prescribe EPSTATE ED when a patient requires both immediate symptom relief and long-term disease modification.\nKey Benefits and Therapeutic Advantages\nComprehensive Multi-Mechanism Action\nThe primary advantage of EPSTATE ED lies in its multi-faceted approach to neuropathic conditions. Rather than addressing only pain symptoms, the formulation simultaneously tackles pain perception, underlying metabolic abnormalities, and nutritional support for nerve health. This comprehensive strategy may lead to superior outcomes compared to monotherapy approaches.\nEnhanced Pain Relief\nClinical evidence supporting Pregabalin's efficacy in neuropathic pain is substantial. Patients often report significant reductions in pain intensity, improved sleep quality due to decreased nocturnal pain, and enhanced ability to perform daily activities. The pain-relieving effects typically manifest within the first week of therapy and continue to improve with ongoing treatment.\nDisease Modification Potential\nUnlike purely symptomatic treatments, the inclusion of Epalrestat provides genuine disease-modifying potential. By targeting the polyol pathway, EPSTATE ED may slow the progression of nerve damage in diabetic patients. Long-term use may preserve nerve function and prevent the worsening of neuropathic symptoms, offering hope beyond mere symptom management.\nImproved Nerve Conduction and Function\nThe combination of metabolic correction through Epalrestat and neurotropic support via Methylcobalamin creates an environment conducive to nerve regeneration and functional improvement. Studies have demonstrated improvements in nerve conduction velocity parameters with similar combination therapies, suggesting potential restoration of nerve function rather than simple symptom masking.\nConvenience of Combination Therapy\nFor patients who would otherwise require multiple separate medications, EPSTATE ED offers the convenience of a single tablet containing all three therapeutic agents. This simplification of medication regimens improves compliance, reduces pill burden, and may enhance overall treatment outcomes.\nQuality of Life Enhancement\nThe cumulative effect of pain reduction, improved nerve function, and better metabolic control translates into meaningful quality of life improvements. Patients report better mobility, reduced interference of pain with daily activities, improved mood, and enhanced social functioning.\nPotential Side Effects and Safety Considerations\nCommon Side Effects\nAs with any pharmaceutical agent, EPSTATE ED may produce certain adverse effects. The most commonly reported side effects are primarily attributable to the Pregabalin component and include dizziness, somnolence, peripheral edema, dry mouth, blurred vision, weight gain, and difficulty with concentration or attention. These effects are generally mild to moderate and often diminish with continued therapy as the body adapts to the medication.\nGastrointestinal symptoms such as constipation or nausea may occur, though they are typically manageable with dietary modifications or symptomatic treatment. Some patients experience increased appetite leading to weight gain, which requires monitoring, particularly in diabetic individuals where weight management is crucial.\nSerious but Rare Adverse Events\nThough uncommon, certain serious adverse effects warrant immediate medical attention. These include allergic reactions manifesting as rash, itching, swelling, severe dizziness, or breathing difficulties. Pregabalin has been associated with rare cases of angioedema, which requires prompt discontinuation and medical intervention.\nMental health changes, including mood alterations, anxiety, depression, agitation, or suicidal thoughts, have been reported with Pregabalin use, particularly in individuals with pre-existing psychiatric conditions. Patients and caregivers should remain vigilant for behavioral changes and report them immediately to healthcare providers.\nDrug Interactions and Precautions\nEPSTATE ED may interact with other central nervous system depressants, including alcohol, opioids, benzodiazepines, and antihistamines, potentially intensifying sedation and cognitive impairment. Patients should inform their healthcare provider of all medications, supplements, and substances they consume.\nIndividuals with kidney impairment require dose adjustments since Pregabalin is primarily eliminated through renal excretion. Regular monitoring of renal function may be necessary during long-term therapy.\nSpecial Population Considerations\nPregnant or breastfeeding women should use EPSTATE ED only when clearly necessary and under strict medical supervision, as the safety profile in these populations has not been fully established. Elderly patients may be more susceptible to side effects, particularly dizziness and confusion, necessitating careful dose titration and monitoring.\nPatients should be advised against abrupt discontinuation of EPSTATE ED, as sudden cessation of Pregabalin may precipitate withdrawal symptoms including insomnia, nausea, headache, anxiety, and sweating. Gradual dose reduction under medical supervision is recommended when discontinuing therapy.\nDosage and Administration Guidelines\nThe appropriate dosage of EPSTATE ED is highly individualized and should be determined by a qualified healthcare professional based on the patient's specific condition, response to therapy, and tolerance. Typically, treatment begins with a lower dose that is gradually increased to achieve optimal therapeutic benefit while minimizing adverse effects.\nPatients should take EPSTATE ED exactly as prescribed, with or without food, at consistent times each day to maintain stable blood levels. Missing doses should be addressed by taking the forgotten dose as soon as remembered, unless it's nearly time for the next scheduled dose. Double dosing to compensate for missed doses is not recommended.\nRegular follow-up appointments allow healthcare providers to assess treatment efficacy, monitor for adverse effects, and make necessary dose adjustments. Patients should maintain open communication with their medical team regarding symptom improvement, side effects, and any concerns that arise during therapy.\nPatient Counseling and Lifestyle Recommendations\nMaximizing the benefits of EPSTATE ED extends beyond simply taking the medication. Patients should be counseled on complementary lifestyle measures that support neuropathy management. Maintaining optimal glycemic control remains paramount for diabetic patients, as blood sugar management directly impacts neuropathy progression regardless of medication.\nRegular physical activity, within individual capabilities, promotes circulation, supports nerve health, and may enhance the therapeutic effects of EPSTATE ED. Daily foot examinations become critical for diabetic patients to identify potential injuries early, preventing serious complications.\nNutritional optimization, including adequate intake of B vitamins, antioxidants, and essential nutrients, supports the neurotropic effects of Methylcobalamin. Avoiding alcohol and tobacco, both of which can exacerbate neuropathy, is strongly recommended.\nPatients should be cautioned about activities requiring alertness, such as driving or operating machinery, especially during the initial treatment phase when dizziness and somnolence may be more pronounced. These effects typically improve with continued therapy, but individual responses vary.\nConclusion\nEPSTATE ED represents a thoughtfully designed pharmaceutical formulation that addresses the multifaceted nature of diabetic neuropathy and neuropathic pain through its unique combination of Pregabalin, Epalrestat, and Methylcobalamin. This triple-action approach offers patients more than symptomatic relief—it provides genuine disease modification potential, nutritional support, and comprehensive nerve health optimization.\nThe synergistic effects of these three components create a therapeutic profile that is greater than the sum of its parts. While Pregabalin efficiently manages pain symptoms and improves quality of life in the short term, Epalrestat works to address underlying metabolic derangements that drive disease progression, and Methylcobalamin provides essential neurotropic support for nerve regeneration and function.\nFor patients struggling with the debilitating effects of neuropathic pain and diabetic neuropathy, EPSTATE ED offers renewed hope for better symptom control and potentially slowed disease progression. The convenience of combination therapy in a single tablet improves adherence and simplifies complex treatment regimens.\nHowever, EPSTATE ED is not without considerations. Potential side effects, though generally manageable, require awareness and monitoring. The medication is most effective when integrated into a comprehensive management plan that includes optimal glycemic control, lifestyle modifications, and regular medical supervision.\nUltimately, EPSTATE ED should be viewed as a valuable tool in the therapeutic arsenal against neuropathic conditions, best utilized under the guidance of knowledgeable healthcare professionals who can individualize treatment to each patient's unique needs and circumstances. With proper use, monitoring, and patient education, EPSTATE ED can significantly improve outcomes and quality of life for those affected by these challenging neurological conditions.",
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"description": "Product Name: FLAVOSHIELD 500\nActive Ingredients: Micronized Purified Flavonoid Fraction (MPFF) 500mg, containing Diosmin 450mg and Hesperidin 50mg.\nPresentation: Oral Tablets\n\nUnveiling FLAVOSHIELD 500: A Deep Dive into Advanced Venous and Vascular Wellness\nIn the intricate network of the human circulatory system, veins perform the silent, relentless task of returning blood to the heart against gravity. When this system faces strain, it can manifest through discomfort, heaviness, and visible changes that impact both physical well-being and quality of life. Enter FLAVOSHIELD 500, a sophisticated pharmaceutical-grade formulation designed to fortify venous health at its core. Powered by a Micronized Purified Flavonoid Fraction (MPFF)—a precise blend of 450mg Diosmin and 50mg Hesperidin—FLAVOSHIELD 500 represents a pinnacle in venoactive therapy. This comprehensive description explores the product, its mechanism, multifaceted uses, key benefits, safety profile, and its role in a holistic health strategy.\n\nWhat is FLAVOSHIELD 500? The Science of MPFF\nFLAVOSHIELD 500 is not a simple herbal supplement; it is a clinically researched, standardized medical treatment. Its active core, the Micronized Purified Flavonoid Fraction, is derived from citrus fruits but undergoes a specialized purification and micronization process. This technological advancement is crucial:\n\nPurification: Ensures a consistent, high-potency concentration of the active flavonoid molecules, Diosmin and Hesperidin, free from plant impurities.\nMicronization: Reduces the particle size of the flavonoids dramatically, increasing their surface area. This leads to significantly enhanced absorption in the gastrointestinal tract, ensuring that a much higher percentage of the active dose reaches the bloodstream and, ultimately, the target venous tissues. Compared to non-micronized diosmin, MPFF offers up to 30% greater bioavailability, making FLAVOSHIELD 500 a more effective and reliable choice.\nThis synergy of Diosmin and Hesperidin works on multiple physiological pathways to restore venous tone and capillary integrity.\n\nPrimary Uses and Therapeutic Applications\nFLAVOSHIELD 500 is indicated for the management of various stages of chronic venous disorders and related conditions:\n\nChronic Venous Disease (CVD) & Venous Insufficiency: This is the primary use. It alleviates the distressing symptoms stemming from weakened vein walls and faulty valves in the legs. These include:\n\nHeaviness and Fatigue: The pervasive feeling of weight and tiredness in the legs, especially after prolonged standing or sitting.\nPain and Aching: Dull, throbbing, or cramping pain that improves with elevation.\nSwelling (Edema): Reduction of ankle and lower leg swelling caused by fluid leakage from capillaries.\nNocturnal Cramps: Relief from painful muscle spasms that often occur at night.\nHemorrhoidal Disease (Acute and Chronic): MPFF is a cornerstone in hemorrhoid management. It treats acute hemorrhoidal attacks by reducing bleeding, pain, and discharge. For chronic cases, it helps prevent recurrences by decreasing capillary fragility and inflammation in the anal venous plexus.\n\nPost-Phlebitic Syndrome: Following deep vein thrombosis (DVT), patients often suffer from chronic leg swelling, pain, and skin changes. FLAVOSHIELD 500 can be part of the management plan to improve microcirculation and reduce symptoms.\n\nSupport Post-Sclerotherapy or Surgical Procedures: It is commonly used after vein stripping, laser ablation, or sclerotherapy to support healing, reduce postoperative swelling and bruising, and help consolidate results.\n\nKey Benefits and Mechanism of Action: The Multi-Target Approach\nThe efficacy of FLAVOSHIELD 500 stems from its multi-faceted pharmacological actions on the venous and lymphatic systems:\n\nVenotonic Action: It increases venous tone and elasticity by promoting the contraction of smooth muscle in the vein walls. This helps veins propel blood more efficiently upward, reducing pooling and pressure. Think of it as “tightening” slackened venous structures.\n\nCapillary-Protective & Anti-Inflammatory Effects: It strengthens capillary walls (reduces capillary permeability) and inhibits the release of inflammatory mediators (like prostaglandins and leukotrienes). This dual action minimizes the leakage of fluid, proteins, and inflammatory cells into surrounding tissues, thereby directly addressing edema (swelling) and inflammation. This is particularly vital in hemorrhoidal tissue.\n\nLymphatic Enhancement: FLAVOSHIELD 500 has been shown to increase lymphatic drainage by boosting the frequency and intensity of lymphatic contractions. This provides an additional route for removing excess interstitial fluid and proteins, further reducing swelling.\n\nAntioxidant Activity: The flavonoids scavenge harmful free radicals, protecting venous and capillary endothelial cells from oxidative stress, which is a contributing factor in chronic venous disease.\n\nImprovement of Microcirculation: By reducing blood viscosity and inhibiting red blood cell aggregation, it improves blood flow in the smallest vessels, enhancing oxygen delivery and waste removal at the tissue level.\n\nPatient-Centric Benefits:\n\nRapid Symptom Relief: Patients often report a noticeable decrease in leg heaviness and pain within the first few weeks of treatment.\nEnhanced Quality of Life: Restores the ability to stand, walk, and engage in daily activities with greater comfort and less discomfort.\nReduced Reliance on Pain Medication: By addressing the underlying inflammation and pain of venous issues and hemorrhoids, it can decrease the need for NSAIDs.\nComplement to Compression Therapy: Works synergistically with compression stockings, often allowing for better tolerance and compliance with compression wear.\nSide Effects and Safety Profile: What to Expect\nFLAVOSHIELD 500 is generally very well-tolerated, with a low incidence of side effects, which are typically mild and transient. This excellent safety profile is a result of its natural origin and high purification.\n\nCommon Side Effects (Rare and usually mild):\n\nGastrointestinal: Some individuals may experience mild, transient digestive disturbances such as nausea, stomach pain, diarrhea, or heartburn. Taking the tablet with a meal can often mitigate this.\nNeurological: Occasional reports of headache or dizziness.\nAllergic Reactions: Very rare cases of skin rash or itching have been reported.\nImportant Safety Considerations:\n\nPregnancy and Lactation: While no teratogenic effects have been demonstrated, as a precaution, use during pregnancy (especially the first trimester) and breastfeeding should only be under the direct supervision of a physician who has weighed the benefits against potential risks.\nDrug Interactions: No significant pharmacokinetic drug interactions have been formally reported. However, as with any medication, it is prudent to inform your doctor about all other medicines and supplements you are taking.\nContraindications: Hypersensitivity to any of the components (Diosmin, Hesperidin, or excipients in the tablet) is a contraindication.\nCrucial Note: FLAVOSHIELD 500 is a treatment for symptoms and a stabilizer of venous function, not a cure for underlying venous valve incompetence. It does not replace definitive interventional treatments (like ablation or surgery) for advanced varicose veins when they are medically indicated. It is essential to receive a proper diagnosis from a healthcare professional to rule out other causes of leg swelling or pain (e.g., cardiac, renal, or hepatic origin).\n\nConclusion: FLAVOSHIELD 500 – A Cornerstone of Comprehensive Venous Care\nIn conclusion, FLAVOSHIELD 500 stands as a robust, scientifically validated agent in the realm of vascular health. Its advanced MPFF technology, combining 450mg of micronized Diosmin with 50mg of Hesperidin, delivers enhanced bioavailability and a powerful, multi-target action that addresses the root causes of venous discomfort: poor tone, capillary fragility, inflammation, and impaired lymphatic drainage.\n\nWhether battling the daily fatigue of heavy legs, managing the acute distress of a hemorrhoidal flare-up, or supporting recovery after a venous procedure, FLAVOSHIELD 500 offers a reliable and well-tolerated therapeutic option. Its benefits in improving symptoms and quality of life are clear, backed by a strong body of clinical evidence.\n\nHowever, optimal venous health is a holistic endeavor. FLAVOSHIELD 500 should be viewed as the pharmacological cornerstone of a broader management plan. This plan should include:\n\nMedical Supervision: Regular consultation with a vascular specialist or phlebologist.\nLifestyle Modifications: Weight management, regular low-impact exercise (walking, swimming), and elevation of the legs.\nCompression Therapy: The use of medically prescribed compression stockings when recommended.\nDietary Awareness: A fiber-rich diet to prevent constipation and straining.\nBy integrating FLAVOSHIELD 500 into this comprehensive approach, individuals can take proactive control of their venous health, shielding their vitality and comfort from the burdens of venous insufficiency. Always consult your healthcare provider to determine if FLAVOSHIELD 500 is appropriate for your specific condition and to establish the correct dosage and treatment duration.\n\nDisclaimer: This content is for informational purposes only and does not constitute medical advice. Always seek the guidance of a qualified healthcare professional with any questions regarding a medical condition or treatment. Do not delay seeking or disregard professional medical advice based on information contained here.",
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