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{ "products": [ { "_id": "69662101a96bbf383231d700", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "FABRICAL MG K₂7", "description": "FABRICAL MG K₂7 represents a scientifically advanced nutritional supplement that combines essential minerals and vitamins in a synergistic formulation designed to support optimal bone health, cardiovascular function, and overall metabolic wellness. This innovative product brings together six critical nutrients—Calcium Citrate Maleate, Magnesium Bisglycinate, Vitamin D3, Vitamin K2-7 (Menaquinone-7), Zinc, and Methylcobalamin—in precise therapeutic ratios that maximize bioavailability and clinical effectiveness.\nUnlike conventional calcium supplements that focus solely on calcium supplementation, FABRICAL MG K₂7 adopts a comprehensive, multi-nutrient approach that addresses the complex interplay between various micronutrients essential for skeletal integrity, neuromuscular function, immune competence, and metabolic regulation. This sophisticated formulation reflects current understanding of nutritional biochemistry, recognizing that optimal health outcomes require balanced supplementation rather than isolated nutrient provision.\nThe product has been meticulously formulated to address the growing epidemic of nutritional deficiencies affecting diverse populations, from elderly individuals experiencing age-related bone loss to young adults with suboptimal dietary intake, pregnant women with increased nutritional demands, and individuals with chronic conditions affecting nutrient absorption or utilization. FABRICAL MG K₂7 serves as a convenient, evidence-based solution for maintaining nutritional adequacy and supporting long-term health across various life stages.\nDetailed Understanding of FABRICAL MG K₂7 Components\nCalcium Citrate Maleate: Superior Calcium Bioavailability\nCalcium Citrate Maleate represents the premium form of calcium supplementation, offering significantly enhanced absorption compared to traditional calcium carbonate. This advanced calcium complex demonstrates approximately 25-30% better bioavailability, making it particularly valuable for individuals with reduced gastric acid production, including elderly populations and those taking proton pump inhibitors or H2-receptor antagonists. Unlike calcium carbonate, which requires acidic conditions for optimal dissolution, Calcium Citrate Maleate can be absorbed efficiently regardless of meal timing or stomach pH, providing greater flexibility and convenience.\nThe maleate component further enhances calcium absorption and utilization by supporting cellular energy metabolism and mitochondrial function. This sophisticated formulation ensures that supplemented calcium reaches target tissues—bones, teeth, muscles, and nerves—where it performs essential physiological functions rather than accumulating in soft tissues where it could potentially contribute to unwanted calcification.\nMagnesium Bisglycinate: The Gentle Magnesium Choice\nMagnesium Bisglycinate, also known as magnesium glycinate, stands as one of the most bioavailable and well-tolerated forms of magnesium supplementation. This chelated form, where magnesium is bound to two molecules of the amino acid glycine, offers exceptional absorption rates approaching 80-90% while minimizing the gastrointestinal side effects—particularly diarrhea—commonly associated with other magnesium forms like magnesium oxide or sulfate.\nMagnesium plays over 300 enzymatic roles throughout the body, making it indispensable for energy production, protein synthesis, muscle and nerve function, blood glucose control, and blood pressure regulation. Within FABRICAL MG K₂7, magnesium works synergistically with calcium, maintaining the critical calcium-magnesium balance essential for proper muscular contraction and relaxation, cardiovascular rhythm stability, and skeletal mineralization.\nVitamin D3: The Sunshine Vitamin in Its Active Form\nVitamin D3 (cholecalciferol) represents the most bioactive form of vitamin D, identical to what human skin synthesizes upon ultraviolet B exposure. This fat-soluble vitamin functions more accurately as a hormone, regulating calcium absorption from the intestines, maintaining serum calcium and phosphorus concentrations within optimal ranges, and modulating bone remodeling by both osteoblasts and osteoclasts.\nBeyond skeletal functions, Vitamin D3 exerts profound influences on immune system regulation, cellular differentiation and proliferation, neuromuscular function, and inflammation modulation. Vitamin D receptors exist throughout the body—in tissues ranging from the brain and heart to immune cells and muscle—highlighting its systemic importance. The inclusion of Vitamin D3 in FABRICAL MG K₂7 ensures that supplemented calcium can be effectively absorbed and utilized, preventing the futility of calcium supplementation in vitamin D-deficient states.\nVitamin K2-7: The Missing Link in Bone and Cardiovascular Health\nVitamin K2-7, specifically the menaquinone-7 (MK-7) form, represents perhaps the most revolutionary component of FABRICAL MG K₂7. This long-chain vitamin K2 demonstrates superior bioavailability and longer half-life compared to vitamin K1 (phylloquinone) found in green vegetables or shorter-chain K2 forms. Vitamin K2-7's critical function involves activating proteins responsible for proper calcium utilization—specifically matrix Gla protein (MGP) and osteocalcin.\nOsteocalcin, produced by bone-building osteoblasts, requires vitamin K2-dependent carboxylation to become active and effectively bind calcium into bone matrix, strengthening skeletal structure. Simultaneously, Vitamin K2-7 activates MGP, which prevents calcium deposition in arterial walls and soft tissues, directing calcium away from cardiovascular structures where it contributes to atherosclerosis and arterial stiffness. This dual action—promoting bone calcification while preventing vascular calcification—makes Vitamin K2-7 uniquely valuable, addressing the “calcium paradox” where individuals may simultaneously experience osteoporosis and arterial calcification.\nZinc: The Multifunctional Essential Mineral\nZinc, incorporated into FABRICAL MG K₂7 in highly bioavailable form, serves numerous critical physiological functions spanning immune competence, wound healing, protein synthesis, DNA synthesis, and cellular division. Regarding bone health specifically, zinc influences bone metabolism by supporting osteoblast activity and collagen synthesis, contributing to bone matrix formation and mineralization. Zinc also functions as a cofactor for alkaline phosphatase, an enzyme essential for bone mineralization.\nBeyond skeletal contributions, zinc supports immune system function, acting as a critical component of innumerable enzymes involved in immune cell development and function. Zinc deficiency impairs both innate and adaptive immunity, increasing susceptibility to infections. The mineral also supports sensory function (taste and smell), cognitive function, reproductive health, and skin integrity.\nMethylcobalamin: The Bioactive Vitamin B12\nMethylcobalamin represents the active, coenzyme form of vitamin B12, requiring no metabolic conversion to exert biological activity. This form demonstrates superior neurological benefits compared to cyanocobalamin, the synthetic form commonly used in supplements. Methylcobalamin directly participates in methionine synthesis and methylation reactions critical for nervous system health, DNA synthesis, red blood cell formation, and homocysteine metabolism.\nElevated homocysteine, resulting from inadequate B12 status, associates with increased cardiovascular disease risk, cognitive decline, and bone fragility. By supporting homocysteine conversion to methionine, methylcobalamin in FABRICAL MG K₂7 contributes to cardiovascular protection and potentially supports bone health through mechanisms independent of its well-established neurological and hematological roles.\nPrimary Uses and Clinical Applications of FABRICAL MG K₂7\nComprehensive Bone Health Support\nThe primary indication for FABRICAL MG K₂7 centers on comprehensive bone health support across various life stages and clinical scenarios. The formulation addresses all critical aspects of skeletal health: providing adequate calcium substrate for mineralization, ensuring calcium absorption through Vitamin D3, directing calcium into bone matrix via Vitamin K2-7, supporting bone matrix formation through magnesium and zinc, and protecting against homocysteine-related bone fragility through methylcobalamin.\nThis makes FABRICAL MG K₂7 particularly valuable for:\nOsteoporosis Prevention and Management: Postmenopausal women and elderly men experiencing age-related bone loss benefit from the formulation's comprehensive approach, potentially slowing bone density decline and reducing fracture risk.\nGrowing Children and Adolescents: During peak bone-building years, FABRICAL MG K₂7 supports optimal skeletal development, helping children and teenagers achieve maximum peak bone mass—a critical determinant of lifelong skeletal health.\nPregnancy and Lactation: Women during pregnancy and breastfeeding experience dramatically increased calcium demands. FABRICAL MG K₂7 helps prevent maternal bone density loss while supporting fetal skeletal development.\nCardiovascular Protection Through Proper Calcium Distribution\nThe Vitamin K2-7 component positions FABRICAL MG K₂7 as more than a bone health supplement—it's a cardiovascular protective formulation. By activating matrix Gla protein, the supplement helps prevent arterial calcification, potentially reducing cardiovascular disease risk. This dual benefit addresses the concerning observation that some individuals taking calcium supplements without adequate Vitamin K2 may experience increased cardiovascular events due to inappropriate calcium deposition in arterial walls.\nNeurological and Cognitive Support\nThe methylcobalamin component provides neurological support, particularly valuable for elderly individuals at risk for vitamin B12 deficiency due to reduced intrinsic factor production or those taking medications that impair B12 absorption (such as metformin or proton pump inhibitors). Adequate B12 status supports cognitive function, mood regulation, nerve conduction, and may help prevent peripheral neuropathy.\nImmune System Enhancement\nBoth zinc and vitamin D3 within FABRICAL MG K₂7 contribute significantly to immune competence. Vitamin D modulates both innate and adaptive immunity, while zinc supports immune cell development and function. This immune support proves particularly relevant during seasonal illness peaks or for individuals with compromised immunity.\nMuscle Function and Exercise Performance\nMagnesium's role in muscle contraction and relaxation, combined with calcium's involvement in excitation-contraction coupling, makes FABRICAL MG K₂7 valuable for athletes and physically active individuals. The formulation may help prevent exercise-associated muscle cramps, support recovery, and maintain electrolyte balance.\nKey Benefits of FABRICAL MG K₂7\nEnhanced Bioavailability and Absorption\nUnlike basic supplements using inferior ingredient forms, FABRICAL MG K₂7 utilizes premium, highly bioavailable compounds:\n\nCalcium Citrate Maleate offers superior absorption compared to calcium carbonate\nMagnesium Bisglycinate provides excellent absorption without gastrointestinal distress\nVitamin D3 is more potent than D2\nVitamin K2-7 (MK-7) has longer half-life and better tissue distribution than K1 or shorter-chain K2 forms\nMethylcobalamin is the active B12 form requiring no conversion\n\nThis superior bioavailability means lower doses can achieve therapeutic effects, reducing pill burden and potential adverse effects while maximizing benefits.\nSynergistic Nutrient Interactions\nFABRICAL MG K₂7's formulation recognizes that nutrients work together, not in isolation:\n\nVitamin D3 enhances calcium absorption while Vitamin K2-7 directs where that calcium goes\nMagnesium supports Vitamin D activation and calcium metabolism\nZinc supports bone matrix formation complementing calcium's role in mineralization\nMethylcobalamin supports methylation pathways that may influence bone health\n\nThis synergy delivers benefits exceeding what individual nutrients could provide separately.\nComprehensive Rather Than Fragmented Nutritional Support\nRather than requiring multiple separate supplements, FABRICAL MG K₂7 provides comprehensive support in a single, convenient formulation. This simplification improves compliance, reduces costs compared to purchasing individual supplements, and eliminates concerns about nutrient imbalances from uncoordinated supplementation.\nProtection Against the Calcium Paradox\nPerhaps the most significant benefit stems from the Vitamin K2-7 inclusion, which addresses the calcium paradox—simultaneously strengthening bones while protecting cardiovascular health by preventing arterial calcification. This represents a critical advancement over traditional calcium supplements that may inadvertently increase cardiovascular risk when taken without adequate Vitamin K2.\nSupport Across Multiple Physiological Systems\nBeyond bones, FABRICAL MG K₂7 benefits:\n\nCardiovascular System: Through arterial protection and homocysteine management\nNervous System: Via methylcobalamin's neurological support\nImmune System: Through vitamin D3 and zinc's immunomodulatory effects\nMuscular System: Via magnesium and calcium's roles in contraction\nMetabolic System: Through magnesium's involvement in glucose metabolism\n\nThis multi-system support delivers value far exceeding simple bone health supplementation.\nPotential Side Effects and Safety Considerations\nGenerally Well-Tolerated with Minimal Side Effects\nFABRICAL MG K₂7, when taken as directed, demonstrates excellent tolerability in most individuals. The selection of highly bioavailable, gentle nutrient forms specifically minimizes adverse effects common with inferior formulations.\nMild Gastrointestinal Effects\nSome users may initially experience mild digestive symptoms including:\n\nSlight nausea, particularly if taken on an empty stomach\nMinor bloating or gas\nMild constipation (though less likely than with calcium carbonate formulations)\n\nThese effects typically resolve within a few days as the body adjusts and can be minimized by taking the supplement with meals and ensuring adequate hydration.\nRare Allergic Reactions\nAlthough uncommon, some individuals may experience hypersensitivity to ingredients or excipients in the formulation. Signs include rash, itching, or swelling. Discontinuation and medical consultation are warranted if such reactions occur.\nConsiderations for Specific Populations\nIndividuals on Anticoagulants: Vitamin K2, while generally safer regarding coagulation than K1, may theoretically interact with warfarin. Patients on anticoagulation therapy should consult healthcare providers before starting FABRICAL MG K₂7, though recent evidence suggests K2 supplementation at consistent doses may not significantly affect INR stability.\nKidney Disease Patients: Individuals with chronic kidney disease should consult nephrologists before supplementing with calcium, magnesium, or vitamin D due to altered mineral metabolism and increased calcification risks in renal impairment.\nHypercalcemia Risk: Those with conditions predisposing to elevated calcium (hyperparathyroidism, sarcoidosis, certain cancers) should avoid supplementation without medical supervision.\nImportance of Appropriate Dosing\nExceeding recommended doses may increase adverse effect risks including:\n\nHypercalcemia (excessive calcium) causing nausea, constipation, kidney stones\nHypermagnesemia (excessive magnesium) causing diarrhea, cardiac abnormalities\nVitamin D toxicity (though requiring very high doses sustained over time)\n\nFollowing manufacturer's recommendations and consulting healthcare providers regarding individual needs ensures safe, effective use.\nRecommended Usage and Dosage Guidelines\nFABRICAL MG K₂7 should be taken according to manufacturer recommendations, typically one to two tablets daily with meals for optimal absorption of fat-soluble vitamins (D3 and K2-7). Taking the supplement with food containing some dietary fat further enhances absorption of these critical nutrients while minimizing potential gastrointestinal discomfort.\nConsistency in timing supports optimal benefits, as regular daily supplementation maintains stable nutrient levels. For individuals on multiple medications, spacing FABRICAL MG K₂7 administration at least two hours from certain medications (particularly thyroid hormones, bisphosphonates, or antibiotics) prevents potential absorption interference.\nIndividual requirements vary based on age, sex, dietary intake, health status, and specific deficiency risks. Healthcare provider consultation helps determine whether standard dosing suffices or whether adjustments are warranted. Periodic monitoring of vitamin D levels and other relevant biomarkers may be recommended to ensure supplementation achieves therapeutic goals without overshooting into excess.\nConclusion: FABRICAL MG K₂7 as a Comprehensive Nutritional Solution\nFABRICAL MG K₂7 stands as a sophisticated, scientifically formulated nutritional supplement that transcends traditional approaches to bone health support. By combining six synergistic nutrients in highly bioavailable forms, this innovative product addresses the complex, interconnected nature of skeletal health, cardiovascular protection, neurological function, and overall metabolic wellness.\nThe formulation's greatest strength lies in its comprehensive approach—recognizing that optimal health outcomes require balanced nutrition rather than isolated nutrient provision. The inclusion of Vitamin K2-7 particularly distinguishes FABRICAL MG K₂7 from conventional calcium supplements, addressing the critical calcium paradox and ensuring supplemented calcium strengthens bones while protecting cardiovascular structures.\nFor individuals seeking to support bone density, prevent osteoporosis, ensure adequate nutritional status during life stages of increased demand, or simply maintain optimal health through evidence-based supplementation, FABRICAL MG K₂7 offers a convenient, effective solution backed by nutritional science. Its excellent tolerability, superior ingredient quality, and multi-system benefits make it suitable for diverse populations from growing adolescents to active adults and elderly individuals concerned about age-related health challenges.\nAs with any nutritional supplement, FABRICAL MG K₂7 works best as part of a comprehensive health strategy including balanced nutrition, regular physical activity, adequate sleep, stress management, and appropriate medical care. It complements rather than replaces healthy lifestyle practices, providing nutritional insurance that helps fill gaps in modern diets while supporting long-term wellness.\nWhether you're proactively supporting your skeletal health, addressing identified nutritional deficiencies, or seeking comprehensive multi-nutrient support, FABRICAL MG K₂7 represents a premium choice that combines scientific sophistication with practical convenience, delivering measurable benefits that support vibrant health across all life stages.\n\nDisclaimer: This information is for educational purposes and does not constitute medical advice. Individual nutritional needs vary significantly based on numerous factors. Consult qualified healthcare professionals before starting any supplement regimen, particularly if you have existing health conditions, take medications, are pregnant or nursing, or have specific health concerns. Keep supplements out of reach of children and store according to manufacturer recommendations to maintain product integrity and safety.", "price": 250.0, "discountamount": 75.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2274, "imageuri": "https://productimages.withfloats.com/actual/696621081f531945cbd90a0c.png", "tileimageuri": "https://productimages.withfloats.com/tile/696621081f531945cbd90a0c.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-13T10:40:01.051Z", "updatedon": "2026-06-09T10:20:10.642Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/fabrical-mg-k-7/2274", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "FABRICAL MG K₂7", "category": "ORTHOLOGYRANG", "tags": [ "calcium citrate maleate magnesium bisglycinate tablets", "calcium citrate maleate with vitamin d3 k2 mk7", "magnesium bisglycinate with methylcobalamin tablets", "calcium citrate maleate vitamin k2-7 tablets", "best calcium citrate maleate tablets for bones", "magnesium bisglycinate tablets for muscle cramps", "methylcobalamin zinc tablets for nerve health", "calcium citrate maleate tablets for osteoporosis", "best calcium supplement with k2-7 for bone strength", "vitamin k2-7 mk7 with calcium benefits", "bone strength tablets with calcium magnesium zinc", "vitamin d3 k2 calcium tablets for elderly", "calcium citrate maleate tablets price in india", "best calcium magnesium vitamin d3 k2 tablets", "best bone health tablets with vitamin k2-7", "calcium magnesium zinc methylcobalamin tablets" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69623e6c95697555dd1afd67", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Esomeprazole and Itopride", "description": "ESMOSTRUM IT: Comprehensive Product Guide\nProduct Overview\nESMOSTRUM IT is an advanced pharmaceutical formulation that combines two potent active ingredients—Esomeprazole and Itopride—to provide comprehensive relief from gastrointestinal disorders. This dual-action medication represents a significant advancement in the management of acid-related digestive conditions and motility disorders. By combining a proton pump inhibitor with a prokinetic agent, ESMOSTRUM IT addresses both the underlying causes and symptomatic manifestations of various digestive ailments, offering patients a complete therapeutic solution in a single, convenient dosage form.\nThe synergistic combination of Esomeprazole and Itopride makes ESMOSTRUM IT particularly effective for individuals suffering from gastroesophageal reflux disease (GERD), functional dyspepsia, and other conditions where both excessive acid production and impaired gastric motility contribute to discomfort and disease progression.\nActive Pharmaceutical Ingredients\nEsomeprazole\nEsomeprazole is the S-isomer of omeprazole and belongs to the class of medications known as proton pump inhibitors (PPIs). It works by specifically and irreversibly blocking the hydrogen-potassium adenosine triphosphatase enzyme system (the proton pump) located in the gastric parietal cells. This mechanism effectively reduces gastric acid secretion, providing sustained relief from acid-related symptoms and allowing damaged esophageal and gastric tissue to heal.\nItopride\nItopride is a prokinetic agent that enhances gastrointestinal motility through a dual mechanism of action. It acts as both a dopamine D2 receptor antagonist and an acetylcholinesterase inhibitor. By blocking dopamine receptors, it removes the inhibitory effect of dopamine on gastrointestinal motility, while its acetylcholinesterase inhibition increases acetylcholine levels, further promoting coordinated gastric contractions and improved gastric emptying.\nTherapeutic Uses and Indications\nESMOSTRUM IT is prescribed for a wide range of gastrointestinal conditions where both acid suppression and enhanced motility are therapeutically beneficial:\nGastroesophageal Reflux Disease (GERD)\nESMOSTRUM IT provides exceptional relief for patients suffering from GERD, a chronic condition where stomach acid frequently flows back into the esophagus. The esomeprazole component reduces acid production, while itopride improves the tone of the lower esophageal sphincter and accelerates gastric emptying, thereby reducing the frequency and severity of reflux episodes.\nFunctional Dyspepsia\nFor patients experiencing persistent or recurrent upper abdominal discomfort without an identifiable organic cause, ESMOSTRUM IT addresses multiple pathophysiological mechanisms. It relieves symptoms such as early satiety, postprandial fullness, epigastric pain, and bloating by normalizing gastric acid levels and improving gastric accommodation and emptying.\nPeptic Ulcer Disease\nESMOSTRUM IT aids in the healing of gastric and duodenal ulcers by creating an optimal healing environment through sustained acid suppression. The prokinetic action of itopride helps prevent stasis of gastric contents, which can exacerbate ulcer symptoms.\nNon-Ulcer Dyspepsia\nMany patients experience dyspeptic symptoms without evidence of ulceration. ESMOSTRUM IT effectively manages these symptoms by addressing both acid hypersecretion and delayed gastric emptying, two key factors in non-ulcer dyspepsia.\nGastroparesis-Related Symptoms\nIn conditions where gastric emptying is significantly delayed, the itopride component of ESMOSTRUM IT helps restore more normal gastric motility patterns, reducing associated symptoms like nausea, vomiting, and abdominal distension.\nKey Benefits and Advantages\nDual Mechanism of Action\nThe primary advantage of ESMOSTRUM IT lies in its comprehensive approach to gastrointestinal health. Rather than addressing only acid production or motility in isolation, this combination therapy tackles both aspects simultaneously, providing more complete symptom relief and better therapeutic outcomes.\nSuperior Acid Suppression\nEsomeprazole offers more consistent and prolonged acid suppression compared to many other acid-reducing medications. It provides sustained relief throughout the day and night, allowing patients to experience fewer breakthrough symptoms and better quality of life.\nEnhanced Gastric Motility\nThe itopride component specifically targets motility issues without crossing the blood-brain barrier significantly, meaning it provides prokinetic benefits with minimal central nervous system side effects. This results in improved gastric emptying, reduced bloating, and decreased feelings of fullness after meals.\nRapid Symptom Relief\nMany patients experience noticeable improvement in their symptoms within the first few days of treatment with ESMOSTRUM IT. The combination therapy addresses multiple symptom pathways simultaneously, leading to faster and more comprehensive relief.\nImproved Quality of Life\nBy effectively managing symptoms such as heartburn, regurgitation, nausea, bloating, and early satiety, ESMOSTRUM IT significantly enhances patients' daily functioning and overall well-being. Patients report better sleep quality, improved dietary tolerance, and reduced anxiety related to their digestive symptoms.\nConvenient Dosing\nThe combination of two active ingredients in a single formulation improves medication adherence by reducing pill burden. Patients appreciate the simplicity of taking one medication instead of multiple separate preparations.\nMucosal Healing Properties\nBeyond symptom relief, ESMOSTRUM IT promotes actual healing of damaged esophageal and gastric mucosa. The reduced acid environment created by esomeprazole allows inflamed and eroded tissue to regenerate properly.\nReduced Risk of Complications\nBy effectively controlling acid reflux and improving gastric emptying, ESMOSTRUM IT helps prevent potential complications of chronic GERD, such as esophageal strictures, Barrett's esophagus, and respiratory complications from aspiration.\nDosage and Administration\nESMOSTRUM IT should be taken exactly as prescribed by a healthcare professional. Typically, the medication is administered orally, preferably before meals to optimize its therapeutic effects. The standard dosing regimen usually involves once or twice daily administration, though individual requirements may vary based on the severity of the condition and patient response.\nThe medication should be swallowed whole with water and should not be crushed, chewed, or split, as this may affect the drug's release mechanism and therapeutic efficacy. Patients should maintain regular dosing schedules to ensure optimal acid suppression and motility enhancement throughout the day.\nSide Effects and Safety Considerations\nLike all medications, ESMOSTRUM IT may cause side effects in some individuals, though not everyone experiences them. Understanding potential adverse effects helps patients identify and report concerning symptoms promptly.\nCommon Side Effects\nGastrointestinal Effects: Some patients may experience diarrhea, constipation, abdominal pain, nausea, or flatulence, particularly during initial treatment. These effects are usually mild and often resolve as the body adjusts to the medication.\nHeadache: Mild to moderate headaches occur in a small percentage of patients and typically diminish with continued use.\nDizziness: Some individuals may experience lightheadedness or dizziness, particularly when standing up quickly.\nDry Mouth: Reduced saliva production may occur, leading to oral dryness and discomfort.\nLess Common Side Effects\nSkin Reactions: Rash, itching, or other dermatological manifestations may develop in sensitive individuals.\nSleep Disturbances: Some patients report insomnia or unusual dreams while taking the medication.\nIncreased Prolactin Levels: Itopride may cause mild elevation in prolactin levels, though clinical manifestations are rare.\nTaste Alterations: Changes in taste perception or metallic taste may occur temporarily.\nSerious Side Effects (Rare)\nWhile uncommon, certain serious adverse effects require immediate medical attention:\n\nSevere allergic reactions including difficulty breathing, facial swelling, or severe skin reactions\nSevere diarrhea that persists or contains blood\nIrregular heartbeat or palpitations\nMuscle weakness or pain\nSeizures or tremors\nSigns of liver problems including jaundice, dark urine, or persistent nausea\n\nLong-Term Considerations\nExtended use of proton pump inhibitors like esomeprazole has been associated with certain risks that patients should discuss with their healthcare providers:\n\nPotential reduction in calcium, magnesium, and vitamin B12 absorption\nSlightly increased risk of bone fractures with prolonged use\nPossible increased susceptibility to certain gastrointestinal infections\nRare cases of kidney problems\n\nRegular monitoring and periodic assessment by healthcare professionals help minimize these risks while maintaining therapeutic benefits.\nPrecautions and Contraindications\nPatients should inform their healthcare provider about all existing medical conditions, particularly liver disease, kidney problems, osteoporosis, low magnesium levels, or any gastrointestinal bleeding. ESMOSTRUM IT may interact with certain medications, including blood thinners, antifungals, HIV medications, and certain antibiotics. A complete medication review ensures safe and effective therapy.\nPregnant or breastfeeding women should only use ESMOSTRUM IT under strict medical supervision, as the safety profile in these populations requires careful consideration of potential risks and benefits.\nLifestyle Recommendations\nFor optimal therapeutic outcomes, patients taking ESMOSTRUM IT should complement their medication regimen with appropriate lifestyle modifications:\n\nAvoid trigger foods that exacerbate acid reflux, such as spicy foods, citrus, chocolate, caffeine, and alcohol\nMaintain a healthy body weight to reduce abdominal pressure\nEat smaller, more frequent meals rather than large portions\nAvoid lying down immediately after eating; wait at least two to three hours\nElevate the head of the bed if nighttime symptoms occur\nQuit smoking, as tobacco use significantly worsens reflux symptoms\nManage stress through relaxation techniques, as stress can exacerbate digestive symptoms\n\nConclusion\nESMOSTRUM IT represents a sophisticated and effective pharmaceutical solution for individuals struggling with complex gastrointestinal disorders involving both acid hypersecretion and impaired motility. By combining the powerful acid-suppressing capabilities of esomeprazole with the prokinetic benefits of itopride, this medication offers comprehensive symptom management that addresses the multifaceted nature of digestive disorders.", "price": 182.0, "discountamount": 54.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2273, "imageuri": "https://productimages.withfloats.com/actual/69623e6fd8491171373812e3.png", "tileimageuri": "https://productimages.withfloats.com/tile/69623e6fd8491171373812e3.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-10T11:56:28.061Z", "updatedon": "2026-04-21T09:38:56.999Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//esomeprazole-and-itopride/2273", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "ESMOSTRUM IT", "category": "GASTROLOGYRANGE", "tags": [ "esomeprazole and itopride", "esomeprazole and itopride capsules uses in hindi", "esomeprazole and itopride capsules uses", "esomeprazole and itopride brand name", "esomeprazole and itopride hydrochloride", "esomeprazole and itopride capsules", "esomeprazole and itopride uses", "esomeprazole and itopride hydrochloride capsules", "esomeprazole and itopride hydrochloride uses", "esomeprazole and itopride hydrochloride price", "esomeprazole and itopride hydrochloride price in india", "buy online Esomeprazole and Itopride" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "695b65af2800555f6696a6cf", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Cinacalcet 60 mg Tablet", "description": "CINASELECT 60: Comprehensive Guide to Cinacalcet 60 mg Tablets\nProduct Overview\nCINASELECT 60 is a pharmaceutical formulation containing Cinacalcet hydrochloride 60 mg as its active ingredient. This medication represents a significant advancement in the management of calcium metabolism disorders, particularly in patients with chronic kidney disease and parathyroid conditions. As a calcimimetic agent, CINASELECT 60 works by mimicking the action of calcium on tissues, helping to restore hormonal balance and mineral homeostasis in the body.\nThe 60 mg dosage strength offers an effective therapeutic option for patients requiring moderate to higher-level intervention in managing parathyroid hormone levels and associated calcium imbalances. CINASELECT 60 is manufactured under strict quality control standards, ensuring consistency, purity, and efficacy in every tablet.\nUnderstanding How CINASELECT 60 Works\nCINASELECT 60 operates through a sophisticated mechanism that targets the calcium-sensing receptors located on the surface of parathyroid gland cells. These receptors play a crucial role in regulating parathyroid hormone secretion, which in turn controls calcium and phosphorus levels in the bloodstream.\nWhen you take CINASELECT 60, the active ingredient cinacalcet binds to these calcium-sensing receptors, increasing their sensitivity to extracellular calcium. This enhanced sensitivity tricks the parathyroid glands into “thinking” there is more calcium present in the blood than there actually is. As a result, the glands reduce their production and release of parathyroid hormone (PTH).\nBy lowering PTH levels, CINASELECT 60 subsequently reduces calcium levels in the blood and decreases the amount of phosphorus absorbed from the intestines. This cascade effect helps restore the delicate mineral balance that is often disrupted in patients with kidney disease or parathyroid disorders.\nPrimary Therapeutic Uses\nSecondary Hyperparathyroidism in Chronic Kidney Disease\nThe primary indication for CINASELECT 60 is the treatment of secondary hyperparathyroidism in adult patients with chronic kidney disease (CKD) who are on dialysis. When kidneys fail to function properly, they cannot adequately regulate calcium and phosphorus levels, leading to excessive parathyroid hormone production. This condition can result in serious complications including bone disease, cardiovascular calcification, and increased mortality risk.\nCINASELECT 60 helps manage this condition by controlling PTH levels, thereby reducing the risk of bone complications such as osteitis fibrosa cystica and preventing the dangerous deposition of calcium in blood vessels and soft tissues.\nHypercalcemia in Parathyroid Carcinoma\nCINASELECT 60 is also indicated for treating hypercalcemia (elevated blood calcium levels) in patients with parathyroid carcinoma, a rare malignant tumor of the parathyroid glands. In these cases, the medication helps control the dangerously high calcium levels that can lead to kidney stones, bone pain, digestive issues, and neurological symptoms.\nPrimary Hyperparathyroidism\nFor patients with severe hypercalcemia due to primary hyperparathyroidism who cannot undergo parathyroidectomy or for whom surgery has failed, CINASELECT 60 offers a valuable medical management option. This provides relief for patients who are not surgical candidates due to advanced age, comorbidities, or other contraindications.\nKey Benefits of CINASELECT 60\nEffective PTH Control\nClinical studies have demonstrated that CINASELECT 60 significantly reduces parathyroid hormone levels in a dose-dependent manner. This reduction helps prevent the cascade of complications associated with elevated PTH, including bone mineral loss and cardiovascular calcification.\nImproved Calcium-Phosphorus Balance\nBy reducing PTH secretion, CINASELECT 60 helps normalize serum calcium and phosphorus levels. This is particularly important in dialysis patients, where mineral imbalances can lead to serious complications affecting bone health, cardiovascular function, and overall quality of life.\nReduced Cardiovascular Risk\nElevated calcium and phosphorus levels contribute to vascular calcification, a major risk factor for cardiovascular disease in patients with chronic kidney disease. By managing these mineral levels, CINASELECT 60 may help reduce the risk of cardiovascular complications, which are the leading cause of death in dialysis patients.\nBone Health Preservation\nUncontrolled secondary hyperparathyroidism leads to renal osteodystrophy, a condition characterized by abnormal bone metabolism. CINASELECT 60 helps protect bone integrity by normalizing PTH levels, potentially reducing fracture risk and preserving bone mineral density.\nAlternative to Surgery\nFor patients with primary hyperparathyroidism or parathyroid carcinoma who cannot undergo surgery, CINASELECT 60 provides an effective medical management option. This is particularly valuable for elderly patients or those with multiple comorbidities that make surgery risky.\nQuality of Life Improvement\nBy controlling symptoms associated with hypercalcemia and hyperparathyroidism, such as bone pain, muscle weakness, fatigue, and digestive issues, CINASELECT 60 can significantly improve patients' overall quality of life and functional capacity.\nConvenient Oral Administration\nCINASELECT 60 is administered orally, making it more convenient than injectable alternatives. This allows for outpatient management and reduces the burden on healthcare facilities and patients.\nPotential Side Effects and Adverse Reactions\nCommon Side Effects\nPatients taking CINASELECT 60 may experience several common side effects, which typically include nausea and vomiting, occurring in approximately 20-30% of patients. These gastrointestinal symptoms are usually mild to moderate and may improve over time as the body adjusts to the medication.\nDiarrhea is another frequent complaint, affecting roughly 20% of users. Some patients also report muscle pain or myalgia, dizziness, loss of appetite, and asthenia (general weakness or fatigue).\nSerious Side Effects Requiring Medical Attention\nHypocalcemia: The most significant risk associated with CINASELECT 60 is the development of low calcium levels in the blood. Severe hypocalcemia can lead to paresthesias (tingling sensations), muscle cramps or spasms, tetany, seizures, and QT interval prolongation on electrocardiogram, which can predispose to dangerous heart rhythm abnormalities.\nGastrointestinal Bleeding: There have been reports of gastrointestinal hemorrhage in patients taking cinacalcet, particularly in those with risk factors such as gastritis, ulcers, or concurrent use of other medications that increase bleeding risk.\nAdynamic Bone Disease: Oversuppression of PTH can lead to adynamic bone disease, a condition where bone turnover becomes abnormally low, potentially weakening bones despite normalized calcium levels.\nCardiovascular Effects: Some patients may experience worsening heart failure or arrhythmias, particularly if hypocalcemia develops. Close monitoring is essential in patients with underlying cardiovascular disease.\nAllergic Reactions: Though rare, hypersensitivity reactions including rash, urticaria, and angioedema have been reported.\nPrecautions and Contraindications\nCINASELECT 60 should not be used in patients with serum calcium levels below the normal range. It requires careful dose adjustment and monitoring in patients with hepatic impairment. The medication may interact with drugs metabolized by the CYP2D6 enzyme system and with medications that affect gastric pH.\nPregnant or breastfeeding women should use CINASELECT 60 only if clearly needed, as its safety in these populations has not been fully established. Regular monitoring of serum calcium, phosphorus, and PTH levels is essential throughout treatment.\nDosage and Administration Guidelines\nCINASELECT 60 should be taken orally with food or shortly after a meal, as this improves absorption and reduces gastrointestinal side effects. Tablets should be swallowed whole and not crushed, chewed, or divided.\nThe typical starting dose for secondary hyperparathyroidism is lower than 60 mg, with gradual titration based on PTH and calcium levels. The 60 mg strength is often used as part of the dose escalation process or as a maintenance dose once optimal PTH control is achieved.\nDose adjustments should be made no more frequently than every two to four weeks, as it takes this long to see the full effect of a dose change on PTH levels. Treatment should be individualized based on laboratory values and clinical response.\nMonitoring Requirements\nPatients on CINASELECT 60 require regular monitoring of serum calcium, phosphorus, and intact PTH levels. Calcium levels should be checked within one week of starting treatment or after any dose adjustment, and then monthly once stable. PTH levels should be measured one to four weeks after initiation or dose adjustment, then every one to three months during maintenance therapy.\nAdditionally, patients should be monitored for signs and symptoms of hypocalcemia, particularly during the initial treatment period. Electrocardiogram monitoring may be appropriate in patients at risk for QT prolongation.\nStorage and Handling\nCINASELECT 60 should be stored at room temperature, away from moisture and direct sunlight. The medication should be kept in its original container with the lid tightly closed to protect from humidity. Keep out of reach of children and pets. Do not use past the expiration date printed on the package.\nConclusion\nCINASELECT 60 (Cinacalcet 60 mg) represents a valuable therapeutic option in the management of secondary hyperparathyroidism associated with chronic kidney disease, hypercalcemia in parathyroid carcinoma, and primary hyperparathyroidism in patients who cannot undergo surgery. Its unique mechanism as a calcimimetic agent provides effective control of parathyroid hormone secretion, helping to restore mineral balance and prevent serious complications.\nThe benefits of CINASELECT 60 extend beyond simple laboratory value normalization. By controlling PTH, calcium, and phosphorus levels, this medication helps preserve bone health, reduce cardiovascular calcification risk, and improve overall quality of life for patients dealing with complex metabolic disorders. For patients who are not surgical candidates, CINASELECT 60 offers hope and effective symptom management.\nHowever, like all medications, CINASELECT 60 must be used judiciously under close medical supervision. The risk of hypocalcemia and other potential side effects necessitates regular laboratory monitoring and open communication between patients and healthcare providers. Patients should report any concerning symptoms promptly and attend all scheduled follow-up appointments.", "price": 740.0, "discountamount": 222.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2266, "imageuri": "https://productimages.withfloats.com/actual/695b65ebf30763183f64d4f7.png", "tileimageuri": "https://productimages.withfloats.com/tile/695b65ebf30763183f64d4f7.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-05T07:18:07.264Z", "updatedon": "2026-05-01T06:30:26.075Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//cinacalcet-60-mg-tablet/2266", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CINASELECT 60", "category": "NEPHROLOGYRANGE", "tags": [ "cinacalcet 60 mg", "cinacalcet mechanism of action.", "cinacalcet uses", "tab cinacalcet.", "cinacalcet dose.", "cinacalcet structure.", "cinacalcet tab.", "calcium and phosphorus levels in the bloodstream.", "parathyroid hormone secretion.", "calcium metabolism disorders.", "chronic kidney disease and parathyroid conditions.", "cinacalcet 60 mg", "cinacalcet 60", "Cinacalcet Tablets 60 mg price in India", "Buy Cinacalcet Tablets 60 mg online", "Cinacalcet 60 mg wholesale price", "Buy Cinacalcet Tablets 60 mg", "Get Cinacalcet Tablets 60 mg at best price" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "694d181a5837f90c86a7e9f9", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Frusemide IP 40mg ", "description": "FRUSIP 40 is a pharmaceutical formulation containing Frusemide IP 40mg as its active ingredient, presented in tablet form for oral administration. This medication belongs to the class of loop diuretics, which are among the most potent diuretic agents available in modern medicine. FRUSIP 40 is specifically designed to help manage conditions associated with fluid retention and elevated blood pressure, offering patients a reliable therapeutic solution for maintaining optimal fluid balance in the body.\nThe formulation adheres to Indian Pharmacopoeia (IP) standards, ensuring consistent quality, purity, and efficacy. Each tablet is precisely manufactured to deliver the exact dosage required for effective treatment while maintaining the highest safety standards in pharmaceutical production.\nUnderstanding Furosemide and Its Mechanism\nFrusemide, also known as furosemide in some regions, is a powerful loop diuretic that works primarily in the kidneys. The medication exerts its therapeutic effect by inhibiting the reabsorption of sodium and chloride in the ascending loop of Henle, a specific segment of the kidney's nephron. This action prevents the body from retaining excess salt and water, leading to increased urine production and the subsequent elimination of accumulated fluids.\nThe “loop” designation comes from the specific site of action within the kidney's loop of Henle, making frusemide significantly more potent than thiazide diuretics that work in different parts of the kidney. This enhanced potency makes FRUSIP 40 particularly valuable in managing conditions requiring substantial fluid removal.\nPrimary Uses and Indications\nFRUSIP 40 is prescribed for various medical conditions where fluid accumulation poses health risks or causes discomfort:\nEdema Management: The medication is highly effective in treating edema (swelling) associated with congestive heart failure, where the heart's reduced pumping efficiency leads to fluid buildup in the lungs, legs, and other tissues. It helps alleviate breathing difficulties and reduces the strain on the cardiovascular system.\nLiver Disease: Patients with cirrhosis or other liver conditions often develop ascites, an accumulation of fluid in the abdominal cavity. FRUSIP 40 helps manage this uncomfortable and potentially dangerous condition by promoting fluid elimination.\nKidney Disorders: In cases of nephrotic syndrome and other renal conditions causing fluid retention, this medication assists in maintaining proper fluid balance, though it must be used judiciously under medical supervision in patients with compromised kidney function.\nHypertension Control: FRUSIP 40 serves as an effective antihypertensive agent, helping to lower blood pressure by reducing blood volume through increased fluid excretion. This is particularly beneficial for patients whose hypertension is resistant to other treatments.\nPulmonary Edema: In acute situations where fluid accumulates in the lungs, this medication can provide rapid relief, making it a valuable tool in emergency medical settings.\nKey Benefits and Therapeutic Advantages\nThe advantages of FRUSIP 40 extend beyond its primary diuretic function, offering patients multiple therapeutic benefits:\nRapid Onset of Action: One of the most significant advantages is the quick response time. Patients typically experience diuretic effects within 30 to 60 minutes of oral administration, with peak effects occurring within one to two hours. This rapid action is particularly valuable in acute situations requiring prompt fluid removal.\nPotent Efficacy: As a loop diuretic, FRUSIP 40 demonstrates superior diuretic potency compared to thiazide diuretics, making it the preferred choice for patients with severe fluid retention or those who haven't responded adequately to milder diuretics.\nCardiovascular Protection: By reducing fluid overload, the medication decreases the workload on the heart, helping to prevent complications in patients with heart failure. This protective effect can significantly improve quality of life and potentially reduce hospitalizations.\nSymptom Relief: Patients often experience notable improvement in symptoms such as shortness of breath, swelling in the extremities, and abdominal distension. This symptomatic relief contributes to enhanced mobility and daily functioning.\nFlexible Dosing: The 40mg strength allows healthcare providers to adjust treatment according to individual patient needs, either maintaining this dose or modifying it based on therapeutic response and tolerance.\nElectrolyte Management: When used under proper medical supervision with appropriate monitoring, the medication allows for controlled fluid management while maintaining awareness of electrolyte balance.\nPotential Side Effects and Considerations\nWhile FRUSIP 40 is generally well-tolerated, patients should be aware of potential side effects:\nCommon Side Effects: These include increased urination frequency (which is expected), dizziness or lightheadedness upon standing (due to reduced blood volume), muscle cramps, and mild headaches. These effects often diminish as the body adjusts to the medication.\nElectrolyte Imbalances: The medication can cause depletion of important electrolytes, including potassium, sodium, magnesium, and calcium. Symptoms may include weakness, irregular heartbeat, confusion, or severe muscle cramps. Regular monitoring through blood tests is essential.\nDehydration Risk: Excessive fluid loss can lead to dehydration, characterized by extreme thirst, dry mouth, decreased urine output, and confusion. Patients must maintain adequate fluid intake as directed by their healthcare provider.\nMetabolic Effects: Some patients may experience increased blood sugar levels, elevated uric acid (potentially triggering gout attacks), or changes in cholesterol levels.\nHearing Changes: Rarely, particularly at higher doses, patients may experience ringing in the ears (tinnitus) or temporary hearing impairment.\nPhotosensitivity: Increased sensitivity to sunlight may occur, requiring appropriate sun protection measures.\nDrug Interactions: FRUSIP 40 can interact with numerous medications, including certain antibiotics, other blood pressure medications, NSAIDs, and lithium, necessitating comprehensive medication review by healthcare providers.\nImportant Safety Information\nPatients taking FRUSIP 40 should inform their healthcare provider about any existing medical conditions, particularly kidney disease, liver disease, diabetes, gout, or lupus. Pregnant and breastfeeding women require special consideration, as the medication crosses the placenta and appears in breast milk.\nRegular monitoring of kidney function, electrolyte levels, and blood pressure is essential for safe and effective therapy. Patients should maintain consistent communication with their healthcare team and report any unusual symptoms promptly.\nConclusion\nFRUSIP 40 (Frusemide IP 40mg Tablets) represents a cornerstone therapy in the management of conditions involving fluid retention and hypertension. Its potent diuretic action, rapid onset, and proven efficacy make it an invaluable tool in cardiovascular and renal medicine. The medication offers significant benefits in symptom relief, cardiovascular protection, and overall quality of life improvement for patients struggling with edema and related conditions.\nHowever, the power of this medication demands respect and proper medical supervision. The potential for electrolyte imbalances and other side effects necessitates regular monitoring and open communication between patients and healthcare providers. When used appropriately under medical guidance, with proper monitoring and patient education, FRUSIP 40 can dramatically improve patient outcomes and help individuals regain control over conditions that significantly impact their daily lives.\nPatients prescribed FRUSIP 40 should view this medication as part of a comprehensive treatment plan that may include dietary modifications, lifestyle changes, and other medications. Success with this therapy depends on adherence to prescribed dosing, regular follow-up appointments, and proactive management of potential side effects. With proper use, FRUSIP 40 continues to serve as a trusted and effective therapeutic option for millions of patients worldwide requiring diuretic therapy.", "price": 14.0, "discountamount": 5.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2255, "imageuri": "https://productimages.withfloats.com/actual/694d1821ad363997d8b04dfb.png", "tileimageuri": "https://productimages.withfloats.com/tile/694d1821ad363997d8b04dfb.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-25T10:55:22.405Z", "updatedon": "2026-04-18T09:37:29.473Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//frusemide-ip-40mg-/2255", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "FRUSIP 40", "category": "UROLOGYRANGE", "tags": [ "FRUSIP 40", "It helps alleviate breathing difficulties and reduces the strain on the cardiovascular system.", "fluid buildup in the lungs, legs, and other tissues.", "Metabolic Effects.", "frusemide 40mg", "tab frusemide 40mg", "frusemide 40mg use", "frusemide 40mg hindi", "frusemide 40mg tablet", "frusemide 40mg uses", "frusemide 40mg price", "tab frusemide 40mg use" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "694cf85408591c1173b54c2f", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Pregabalin Epalrestat and Methylcobalamin Tablets", "description": "EPSTATE ED represents an advanced pharmaceutical formulation that combines three powerful therapeutic agents: Pregabalin, Epalrestat, and Methylcobalamin. This innovative triple-combination medication is specifically designed to address the complex pathophysiology of diabetic neuropathy and neuropathic pain conditions. By integrating multiple mechanisms of action, EPSTATE ED offers a comprehensive approach to managing nerve-related complications that significantly impact the quality of life for millions of individuals worldwide.\nThe formulation addresses not only the symptomatic relief of neuropathic pain but also targets the underlying metabolic derangements that contribute to nerve damage progression. This multi-pronged therapeutic strategy makes EPSTATE ED particularly valuable for patients who require more than symptomatic management alone.\nUnderstanding the Active Components\nPregabalin: The Neuropathic Pain Modulator\nPregabalin serves as the cornerstone analgesic component in EPSTATE ED. This anticonvulsant medication works by binding to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. Through this mechanism, Pregabalin reduces the release of excitatory neurotransmitters including glutamate, norepinephrine, and substance P. This reduction in neurotransmitter release effectively dampens the abnormal neural signaling that characterizes neuropathic pain conditions.\nThe molecule demonstrates excellent bioavailability and rapid absorption, allowing patients to experience relief within a relatively short timeframe. Its efficacy in managing various neuropathic pain syndromes has been extensively documented in clinical trials, establishing it as a first-line agent for diabetic peripheral neuropathy, postherpetic neuralgia, and other chronic neuropathic pain conditions.\nEpalrestat: The Aldose Reductase Inhibitor\nEpalrestat represents a unique addition to the formulation, functioning as a selective aldose reductase inhibitor. In diabetic conditions, excess glucose is converted to sorbitol through the polyol pathway, with aldose reductase serving as the rate-limiting enzyme. The accumulation of sorbitol within nerve cells leads to osmotic stress, depletion of myoinositol, and subsequent nerve dysfunction.\nBy inhibiting aldose reductase, Epalrestat prevents this harmful sorbitol accumulation, thereby addressing one of the fundamental metabolic abnormalities responsible for diabetic neuropathy. This disease-modifying approach distinguishes EPSTATE ED from purely symptomatic treatments. Epalrestat has been particularly well-studied in Asian populations and has demonstrated the ability to improve nerve conduction velocities and reduce subjective neuropathic symptoms over time.\nMethylcobalamin: The Neurotropic Vitamin\nMethylcobalamin, the bioactive form of Vitamin B12, completes the therapeutic triad in EPSTATE ED. Unlike cyanocobalamin, which requires conversion in the body, methylcobalamin is immediately available for utilization in crucial biochemical processes. It plays an indispensable role in myelin synthesis, the protective sheath surrounding nerve fibers that enables proper signal transmission.\nThis coenzyme participates in methionine synthesis and is essential for maintaining the structural and functional integrity of neurons. Methylcobalamin also facilitates nerve regeneration and has demonstrated neuroprotective properties in various experimental models. For patients with diabetic neuropathy, who often exhibit Vitamin B12 deficiency (sometimes exacerbated by metformin therapy), supplementation with methylcobalamin addresses both nutritional deficits and supports nerve health at a fundamental level.\nClinical Applications and Uses\nEPSTATE ED is primarily indicated for the comprehensive management of diabetic peripheral neuropathy, a condition affecting approximately 50% of individuals with long-standing diabetes. The symptoms of this condition range from tingling sensations and burning pain to numbness and loss of protective sensation, which can lead to serious complications including foot ulcers and amputations.\nBeyond diabetic neuropathy, EPSTATE ED may be prescribed for various neuropathic pain syndromes where the combination of pain relief, metabolic correction, and nerve support proves beneficial. Patients experiencing chronic nerve pain resulting from metabolic disturbances, nutritional deficiencies, or structural nerve damage may find this combination particularly effective.\nThe medication is typically recommended for adults who have not achieved adequate symptom control with single-agent therapy or who would benefit from the synergistic effects of the three components. Healthcare providers may prescribe EPSTATE ED when a patient requires both immediate symptom relief and long-term disease modification.\nKey Benefits and Therapeutic Advantages\nComprehensive Multi-Mechanism Action\nThe primary advantage of EPSTATE ED lies in its multi-faceted approach to neuropathic conditions. Rather than addressing only pain symptoms, the formulation simultaneously tackles pain perception, underlying metabolic abnormalities, and nutritional support for nerve health. This comprehensive strategy may lead to superior outcomes compared to monotherapy approaches.\nEnhanced Pain Relief\nClinical evidence supporting Pregabalin's efficacy in neuropathic pain is substantial. Patients often report significant reductions in pain intensity, improved sleep quality due to decreased nocturnal pain, and enhanced ability to perform daily activities. The pain-relieving effects typically manifest within the first week of therapy and continue to improve with ongoing treatment.\nDisease Modification Potential\nUnlike purely symptomatic treatments, the inclusion of Epalrestat provides genuine disease-modifying potential. By targeting the polyol pathway, EPSTATE ED may slow the progression of nerve damage in diabetic patients. Long-term use may preserve nerve function and prevent the worsening of neuropathic symptoms, offering hope beyond mere symptom management.\nImproved Nerve Conduction and Function\nThe combination of metabolic correction through Epalrestat and neurotropic support via Methylcobalamin creates an environment conducive to nerve regeneration and functional improvement. Studies have demonstrated improvements in nerve conduction velocity parameters with similar combination therapies, suggesting potential restoration of nerve function rather than simple symptom masking.\nConvenience of Combination Therapy\nFor patients who would otherwise require multiple separate medications, EPSTATE ED offers the convenience of a single tablet containing all three therapeutic agents. This simplification of medication regimens improves compliance, reduces pill burden, and may enhance overall treatment outcomes.\nQuality of Life Enhancement\nThe cumulative effect of pain reduction, improved nerve function, and better metabolic control translates into meaningful quality of life improvements. Patients report better mobility, reduced interference of pain with daily activities, improved mood, and enhanced social functioning.\nPotential Side Effects and Safety Considerations\nCommon Side Effects\nAs with any pharmaceutical agent, EPSTATE ED may produce certain adverse effects. The most commonly reported side effects are primarily attributable to the Pregabalin component and include dizziness, somnolence, peripheral edema, dry mouth, blurred vision, weight gain, and difficulty with concentration or attention. These effects are generally mild to moderate and often diminish with continued therapy as the body adapts to the medication.\nGastrointestinal symptoms such as constipation or nausea may occur, though they are typically manageable with dietary modifications or symptomatic treatment. Some patients experience increased appetite leading to weight gain, which requires monitoring, particularly in diabetic individuals where weight management is crucial.\nSerious but Rare Adverse Events\nThough uncommon, certain serious adverse effects warrant immediate medical attention. These include allergic reactions manifesting as rash, itching, swelling, severe dizziness, or breathing difficulties. Pregabalin has been associated with rare cases of angioedema, which requires prompt discontinuation and medical intervention.\nMental health changes, including mood alterations, anxiety, depression, agitation, or suicidal thoughts, have been reported with Pregabalin use, particularly in individuals with pre-existing psychiatric conditions. Patients and caregivers should remain vigilant for behavioral changes and report them immediately to healthcare providers.\nDrug Interactions and Precautions\nEPSTATE ED may interact with other central nervous system depressants, including alcohol, opioids, benzodiazepines, and antihistamines, potentially intensifying sedation and cognitive impairment. Patients should inform their healthcare provider of all medications, supplements, and substances they consume.\nIndividuals with kidney impairment require dose adjustments since Pregabalin is primarily eliminated through renal excretion. Regular monitoring of renal function may be necessary during long-term therapy.\nSpecial Population Considerations\nPregnant or breastfeeding women should use EPSTATE ED only when clearly necessary and under strict medical supervision, as the safety profile in these populations has not been fully established. Elderly patients may be more susceptible to side effects, particularly dizziness and confusion, necessitating careful dose titration and monitoring.\nPatients should be advised against abrupt discontinuation of EPSTATE ED, as sudden cessation of Pregabalin may precipitate withdrawal symptoms including insomnia, nausea, headache, anxiety, and sweating. Gradual dose reduction under medical supervision is recommended when discontinuing therapy.\nDosage and Administration Guidelines\nThe appropriate dosage of EPSTATE ED is highly individualized and should be determined by a qualified healthcare professional based on the patient's specific condition, response to therapy, and tolerance. Typically, treatment begins with a lower dose that is gradually increased to achieve optimal therapeutic benefit while minimizing adverse effects.\nPatients should take EPSTATE ED exactly as prescribed, with or without food, at consistent times each day to maintain stable blood levels. Missing doses should be addressed by taking the forgotten dose as soon as remembered, unless it's nearly time for the next scheduled dose. Double dosing to compensate for missed doses is not recommended.\nRegular follow-up appointments allow healthcare providers to assess treatment efficacy, monitor for adverse effects, and make necessary dose adjustments. Patients should maintain open communication with their medical team regarding symptom improvement, side effects, and any concerns that arise during therapy.\nPatient Counseling and Lifestyle Recommendations\nMaximizing the benefits of EPSTATE ED extends beyond simply taking the medication. Patients should be counseled on complementary lifestyle measures that support neuropathy management. Maintaining optimal glycemic control remains paramount for diabetic patients, as blood sugar management directly impacts neuropathy progression regardless of medication.\nRegular physical activity, within individual capabilities, promotes circulation, supports nerve health, and may enhance the therapeutic effects of EPSTATE ED. Daily foot examinations become critical for diabetic patients to identify potential injuries early, preventing serious complications.\nNutritional optimization, including adequate intake of B vitamins, antioxidants, and essential nutrients, supports the neurotropic effects of Methylcobalamin. Avoiding alcohol and tobacco, both of which can exacerbate neuropathy, is strongly recommended.\nPatients should be cautioned about activities requiring alertness, such as driving or operating machinery, especially during the initial treatment phase when dizziness and somnolence may be more pronounced. These effects typically improve with continued therapy, but individual responses vary.\nConclusion\nEPSTATE ED represents a thoughtfully designed pharmaceutical formulation that addresses the multifaceted nature of diabetic neuropathy and neuropathic pain through its unique combination of Pregabalin, Epalrestat, and Methylcobalamin. This triple-action approach offers patients more than symptomatic relief—it provides genuine disease modification potential, nutritional support, and comprehensive nerve health optimization.\nThe synergistic effects of these three components create a therapeutic profile that is greater than the sum of its parts. While Pregabalin efficiently manages pain symptoms and improves quality of life in the short term, Epalrestat works to address underlying metabolic derangements that drive disease progression, and Methylcobalamin provides essential neurotropic support for nerve regeneration and function.\nFor patients struggling with the debilitating effects of neuropathic pain and diabetic neuropathy, EPSTATE ED offers renewed hope for better symptom control and potentially slowed disease progression. The convenience of combination therapy in a single tablet improves adherence and simplifies complex treatment regimens.\nHowever, EPSTATE ED is not without considerations. Potential side effects, though generally manageable, require awareness and monitoring. The medication is most effective when integrated into a comprehensive management plan that includes optimal glycemic control, lifestyle modifications, and regular medical supervision.\nUltimately, EPSTATE ED should be viewed as a valuable tool in the therapeutic arsenal against neuropathic conditions, best utilized under the guidance of knowledgeable healthcare professionals who can individualize treatment to each patient's unique needs and circumstances. With proper use, monitoring, and patient education, EPSTATE ED can significantly improve outcomes and quality of life for those affected by these challenging neurological conditions.", "price": 275.0, "discountamount": 82.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2253, "imageuri": "https://productimages.withfloats.com/actual/694cf859d25fa0b0657b1ac8.png", "tileimageuri": "https://productimages.withfloats.com/tile/694cf859d25fa0b0657b1ac8.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-25T08:39:48.947Z", "updatedon": "2026-04-18T09:21:49.885Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//pregabalin-epalrestat-and-methylcobalamin-tablets/2253", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "EPSTATE ED", "category": "NEUROLOGYRANGE", "tags": [ "regabalin, Epalrestat, and Methylcobalamin.neuropathic pain conditions.", "Pregabalin, Epalrestat, and Methylcobalamin.", "neuropathic pain.", "diabetic neuropathy.", "sorbitol within nerve cells leads to osmotic stress.", "Epalrestat and neurotropic support via Methylcobalamin creates an environment .", "mood alterations, anxiety, depression, agitation.", "supports the neurotropic effects of Methylcobalamin.", "Pregabalin Epalrestat and Methylcobalamin Tablets", "epalrestat and methylcobalamin tablets uses", "epalrestat and methylcobalamin tablets in hindi", "pregabalin epalrestat and methylcobalamin tablets price jaipur", "pregabalin epalrestat and methylcobalamin tablets price india" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "693c0c9c0c30ac5c9f8203b4", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Isosorbide Mononitrate IP 30mg Tablets", "description": "CARDULES ISMN SR 30 tablets provide sustained-release Isosorbide Mononitrate IP 30mg, a nitrate medication designed for long-term management of angina in patients with coronary artery disease. This formulation from Steris Healthcare Pvt Ltd ensures steady vasodilation to improve heart blood flow and reduce chest pain episodes. It supports daily activities by minimizing oxygen demand on the heart muscle.​\nProduct Overview\nCARDULES ISMN SR 30 contains Isosorbide Mononitrate IP 30mg in a sustained-release matrix, allowing once-daily dosing for consistent therapeutic levels over 12-24 hours. The tablet's extended-release technology prevents peak-trough fluctuations common in immediate-release forms, promoting better patient compliance. Each film-coated tablet delivers precise bioavailability, with the active metabolite nitric oxide activating guanylate cyclase to boost cyclic GMP, relaxing vascular smooth muscle primarily in veins.​\n\nThis mechanism reduces preload (venous return to the heart) and afterload (arterial resistance), easing cardiac workload without significantly affecting heart rate. Unlike short-acting nitrates for acute relief, CARDULES ISMN SR 30 targets prophylaxis in chronic stable angina, often prescribed alongside beta-blockers or calcium channel blockers. Available in strips of 10 tablets, it undergoes rigorous quality testing at Steris facilities to meet IP standards, ensuring purity and stability.​\n\nKey Uses\nCARDULES ISMN SR 30 primarily prevents angina pectoris in coronary artery disease, where narrowed vessels limit oxygen supply during exertion. Patients experience fewer chest pain attacks during walking, climbing stairs, or stress.​\n\nIt manages chronic stable angina by enhancing myocardial perfusion, suitable for long-term therapy in adults over 18. Healthcare providers may use it adjunctively for coronary spasm or post-myocardial infarction prophylaxis to stabilize symptoms.​\n\nIn select cases, it aids heart failure management by offloading the heart, though not as monotherapy. Always initiate under cardiology supervision with dose titration to tolerance.​\n\nMajor Benefits\nThe sustained-release profile offers 24-hour protection with single morning dosing, improving adherence and lifestyle quality for active patients. It boosts exercise tolerance by 20-30% in trials, allowing longer physical efforts without angina onset.​\n\nBy dilating vessels, it decreases ischemia risk, potentially lowering hospitalization rates for acute episodes. Compared to placebo, users report halved attack frequency within weeks, enhancing daily productivity and emotional well-being.​\n\nBenefit\tMechanism\tPatient Outcome\nAngina Prevention\tVasodilation reduces preload/afterload ​\tFewer attacks, better exertion capacity\nSteady Relief\tSR formulation maintains levels ​\tOnce-daily convenience, no fluctuations\nHeart Protection\tImproves O2 delivery ​\tReduced ischemia, enhanced QoL\nCompliance Boost\tSimple regimen ​\tHigher adherence vs multiple doses\nAdditional perks include minimal impact on blood pressure in normotensives and compatibility with anti-anginals, making it versatile in combo therapy.\n\nPotential Side Effects\nCommon effects include headache (dose-related, often transient in first week), dizziness, or flushing due to vasodilation—hydrate and rise slowly to manage. Gastrointestinal upset like nausea occurs in 5-10% initially.​\n\nOrthostatic hypotension risks fainting, especially early; avoid alcohol or other vasodilators. Rare serious issues encompass severe hypotension, tachycardia, or methemoglobinemia with overdose—monitor blood pressure regularly.​\n\nAllergic reactions (rash, itching) or vision changes warrant discontinuation. Contraindicated in hypotension, glaucoma, or recent PDE5 inhibitor use; caution in anemia or hypothyroidism.​\n\nDosage Guidelines\nStart with 30mg once daily upon waking, swallowed whole without crushing. Titrate to 60mg if tolerated after 3-7 days, max 120mg/day. Take on empty stomach for optimal absorption; avoid late dosing to prevent nocturnal headaches.​\n\nAdjust for elderly or renal/hepatic impairment. Tolerance may develop—nitrate-free interval (evening) helps sustain efficacy. Store below 30°C.​\nConclusion\nCARDULES ISMN SR 30 empowers angina patients with reliable, once-daily prevention, restoring confidence in routine activities under Steris Healthcare's quality assurance. Its targeted vasodilation balances efficacy and tolerability for sustained heart health", "price": 65.0, "discountamount": 19.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2243, "imageuri": "https://productimages.withfloats.com/actual/693c0ca6391a3fa44b0608d8.png", "tileimageuri": "https://productimages.withfloats.com/tile/693c0ca6391a3fa44b0608d8.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-12T12:37:48.92Z", "updatedon": "2026-03-14T08:21:58.091Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//isosorbide-mononitrate-ip-30mg-tablets/2243", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CARDULES ISMN SR 30", "category": "", "tags": [ "Isosorbide Mononitrate IP 30mg Tablets", "coronary artery disease", "heart blood flow and reduce chest pain episodes", "oxygen demand on the heart muscle", "relaxing vascular smooth muscle primarily in veins" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69142bf71d499513a92e5772", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Nicorandil Tablets 5mg", "description": "Nicorandil Tablets 5 mg is a vasodilatory anti-anginal medication widely prescribed for the management and prevention of angina pectoris (chest pain) associated with coronary artery disease (CAD). Angina results from an imbalance between the heart’s oxygen demand and supply due to restricted blood flow in the coronary arteries. Nicorandil offers a dual mechanism of action — acting both as a nitrate-like vasodilator and a potassium channel opener, making it unique among anti-anginal agents.\n\nBy improving oxygen delivery to the myocardium and reducing cardiac workload, Nicorandil 5 mg Tablets provide effective relief from anginal pain and reduce the frequency and severity of ischemic episodes. It is also beneficial in preventing future attacks, improving exercise tolerance, and enhancing the overall quality of life in patients with chronic stable angina.\n\nComposition\n\nEach tablet contains:\n\nNicorandil IP – 5 mg\n\nExcipients – q.s.\n\nNicorandil tablets are available in film-coated form to ensure stability, easy swallowing, and optimal absorption. They are manufactured in compliance with Good Manufacturing Practices (GMP) standards to ensure safety, purity, and efficacy.\n\nPharmacological Action / Mechanism of Action\n\nNicorandil exhibits a dual mechanism that makes it distinct among anti-anginal drugs:\n\nNitrate-Like Effect:\nNicorandil acts as a nitric oxide (NO) donor. Nitric oxide activates guanylate cyclase, increasing cyclic GMP (cGMP) levels in vascular smooth muscle. This leads to relaxation of blood vessels, particularly veins and large arteries, thereby reducing preload and afterload on the heart. This nitrate-like activity lowers myocardial oxygen demand.\n\nPotassium Channel Opening Effect:\nNicorandil opens ATP-sensitive potassium (KATP) channels in vascular smooth muscle, resulting in arteriolar vasodilation. This increases coronary blood flow and improves oxygen supply to ischemic heart tissues.\n\nTogether, these effects reduce cardiac workload, enhance coronary perfusion, and prevent anginal pain by correcting the oxygen supply-demand mismatch in the heart muscle.\n\nUses and Indications\n\nNicorandil Tablets 5 mg are indicated for the treatment and prevention of angina pectoris in adults, particularly:\n\nChronic Stable Angina:\n\nHelps reduce the frequency and severity of chest pain associated with exertion or emotional stress.\n\nProphylaxis of Angina Attacks:\n\nUsed regularly to prevent anginal episodes, especially in patients with known coronary artery disease.\n\nAdjunct Therapy in Ischemic Heart Disease (IHD):\n\nCan be used alongside beta-blockers, calcium channel blockers, or antiplatelet drugs for enhanced symptom control and long-term protection.\n\nImprovement of Exercise Tolerance:\n\nReduces the likelihood of anginal pain during physical activity, enabling patients to perform daily tasks comfortably.\n\nIn some clinical cases, Nicorandil is also considered for post-myocardial infarction recovery, as it improves coronary perfusion, although this is at the discretion of a cardiologist.\n\nDosage and Administration\n\nRecommended Starting Dose: 5 mg to 10 mg twice daily.\n\nMaintenance Dose: May be increased gradually to 10–20 mg twice daily, depending on clinical response and tolerance.\n\nThe tablets should be swallowed whole with water, preferably at the same times each day.\n\nNicorandil should not be stopped abruptly; dosage tapering is recommended to avoid rebound angina.\n\nAlways follow the dosage instructions provided by the physician.\n\nKey Benefits\n\nDual Mechanism for Comprehensive Relief:\nCombines nitrate-like and potassium channel-opening properties for both arterial and venous dilation, providing superior protection against anginal attacks.\n\nImproves Coronary Blood Flow:\nDilates coronary arteries, increasing oxygen delivery to ischemic myocardial tissues.\n\nReduces Cardiac Workload:\nBy decreasing preload (venous return) and afterload (arterial resistance), Nicorandil minimizes the heart’s oxygen consumption.\n\nRapid Onset of Action:\nNicorandil acts within a short duration, offering quick relief from anginal discomfort.\n\nPrevents Future Angina Episodes:\nRegular use helps maintain steady control of chest pain, improving exercise capacity and quality of life.\n\nCompatible with Other Cardiac Medications:\nCan be safely used alongside antiplatelet agents, beta-blockers, ACE inhibitors, and statins as part of comprehensive cardiac care.\n\nFavorable Safety Profile:\nCompared to nitrates, Nicorandil carries a lower risk of tolerance development, making it suitable for long-term therapy.\n\nEnhances Myocardial Protection:\nNicorandil’s KATP channel activation provides additional cardioprotective effects by improving microvascular blood flow and limiting ischemic damage during stress.\n\nPrecautions and Warnings\n\nAlthough Nicorandil is generally well-tolerated, certain precautions are advised:\n\nHypotension:\nNicorandil may cause a drop in blood pressure due to vasodilation. Caution is advised in patients with hypotension or dehydration.\n\nConcurrent Use with Nitrates:\nShould not be used together with other nitrate medications to avoid severe hypotension.\n\nOral or Gastrointestinal Ulcers:\nRarely, Nicorandil may cause ulcerations in the mouth, intestines, or skin. Treatment should be discontinued if ulceration occurs.\n\nPatients with Low Blood Volume:\nUse cautiously in individuals with hypovolemia or those on diuretics.\n\nDriving and Machinery:\nDizziness or light-headedness may occur; avoid driving until effects are known.\n\nPregnancy and Lactation:\nShould be used only if prescribed by a physician when the potential benefits outweigh the risks.\n\nPossible Side Effects\n\nNicorandil is generally safe but may cause some side effects, particularly at the start of therapy or with higher doses. Common and rare adverse reactions include:\n\nCommon Side Effects:\n\nHeadache (due to vasodilation)\n\nFlushing or warmth sensation\n\nDizziness or light-headedness\n\nNausea or mild stomach upset\n\nFatigue or weakness\n\nLess Common / Rare Side Effects:\n\nHypotension (low blood pressure)\n\nPalpitations or tachycardia\n\nMouth ulcers, anal ulcers, or skin ulceration (uncommon but serious — discontinue if occurs)\n\nRash or allergic reaction\n\nVisual disturbances (rare and usually reversible)\n\nIf any severe reaction or persistent discomfort occurs, medical attention should be sought promptly.\n\nDrug Interactions\n\nAvoid concomitant use with nitrates or phosphodiesterase type-5 inhibitors (e.g., Sildenafil, Tadalafil), as it may cause a dangerous fall in blood pressure.\n\nCaution with antihypertensive drugs or diuretics, which may enhance hypotensive effects.\n\nAlcohol consumption can potentiate dizziness or hypotension and should be limited.\n\nStorage and Handling\n\nStore below 30°C, protected from moisture and direct sunlight.\n\nKeep out of reach of children.\n\nDo not use tablets past the expiry date or if the packaging is damaged.\n\nConclusion\n\nNicorandil Tablets 5 mg offer a modern and effective approach to managing angina pectoris, providing reliable relief through their dual-action mechanism. By combining nitrate-like vasodilation with potassium channel opening, Nicorandil ensures both oxygen supply improvement and reduction of cardiac workload — the cornerstone of angina management.\n\nIt is well-tolerated, fast-acting, and suitable for long-term therapy, making it a preferred choice for patients with chronic stable angina. Regular use under medical supervision helps reduce the frequency of chest pain, improve physical endurance, and enhance the overall quality of life in individuals with coronary artery disease.", "price": 381.0, "discountamount": 115.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2202, "imageuri": "https://productimages.withfloats.com/actual/69142c03b53db80943abd33d.png", "tileimageuri": "https://productimages.withfloats.com/tile/69142c03b53db80943abd33d.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-12T06:40:55.795Z", "updatedon": "2026-03-16T08:18:00.245Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//nicorandil-tablets-5mg/2202", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MAYORANDIL 5 ", "category": "CARDIOLOGYRANGE", "tags": [ "nicorandil tablets 5mg", "nicorandil 5 mg tablets uses", "nicorandil tablet 5mg benefits", "nicorandil 5mg medicine", "nicorandil tablets ip 5 mg", "what is nicorandil 5mg used for", "how does nicorandil tablet work", "nicorandil 5mg mechanism of action", "nicorandil tablets for angina treatment", "nicorandil tablet uses in heart disease", "nicorandil 5mg tablet price in india", "buy nicorandil 5mg tablets online", "nicorandil 5mg tablet brands", "nicorandil tablets manufacturer", "nicorandil tablets wholesale supplier" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "68b6d892c8730ef2a3e86287", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Liposomal Calcium Absorption with vitamin k2-7 and vitamin d2 syrup", "description": "Description: \nFABRICAL LIPO SYRUP is a scientifically formulated liposomal calcium supplement designed to support optimal bone strength, improved calcium utilization, and overall skeletal health. Unlike conventional calcium syrups, FABRICAL LIPO SYRUP uses advanced liposomal delivery technology to enhance absorption and bioavailability. This ensures that your body receives maximum benefit from every dose.\n\nCalcium alone is not enough for maintaining strong bones and teeth. Proper absorption and distribution are equally important. That is why FABRICAL LIPO SYRUP combines liposomal calcium with Vitamin K2-7 (Menaquinone-7) and Vitamin D2 (Ergocalciferol) — a powerful trio that works synergistically to strengthen bones, support cardiovascular health, and promote balanced calcium metabolism.\n\nThis syrup is ideal for growing children, adults, elderly individuals, pregnant and lactating women (under medical supervision), and people at risk of calcium deficiency.\n\nKey Ingredients & Their Roles\n1. Liposomal Calcium\n\nLiposomal calcium is encapsulated within microscopic lipid spheres (liposomes). This advanced delivery method protects calcium from degradation in the digestive system and allows better absorption through intestinal walls. Compared to traditional calcium salts, liposomal calcium is gentler on the stomach and more efficiently utilized by the body.\n\nRole:\n\nSupports bone density\n\nMaintains strong teeth\n\nAssists muscle contraction\n\nSupports nerve signaling\n\nHelps in proper heart rhythm\n\n2. Vitamin K2-7 (Menaquinone-7)\n\nVitamin K2-7 plays a crucial role in directing calcium to the bones and teeth while preventing its accumulation in soft tissues and arteries. It activates osteocalcin, a protein responsible for binding calcium to the bone matrix.\n\nRole:\n\nEnhances bone mineralization\n\nPrevents arterial calcification\n\nSupports cardiovascular health\n\nImproves long-term bone strength\n\n3. Vitamin D2 (Ergocalciferol)\n\nVitamin D2 enhances calcium absorption from the intestines. Without adequate Vitamin D, calcium intake may not be effectively utilized by the body.\n\nRole:\n\nIncreases calcium absorption\n\nSupports immune function\n\nPromotes bone remodeling\n\nHelps maintain normal blood calcium levels\n\nHow FABRICAL LIPO SYRUP Works\n\nThe strength of FABRICAL LIPO SYRUP lies in its synergistic formulation:\n\nVitamin D2 increases calcium absorption from the digestive tract.\n\nLiposomal technology ensures enhanced delivery into the bloodstream.\n\nVitamin K2-7 directs calcium toward bones and away from arteries.\n\nThis coordinated mechanism ensures that calcium is not just absorbed, but properly utilized where the body needs it most.\n\nUses of FABRICAL LIPO SYRUP\n\nFABRICAL LIPO SYRUP is commonly recommended for:\n\n1. Bone Health Support\n\nHelps improve bone density and reduce the risk of fractures, particularly in aging individuals.\n\n2. Calcium Deficiency\n\nUseful in individuals with low dietary calcium intake or poor absorption.\n\n3. Osteopenia & Osteoporosis Management\n\nSupports bone mineral density in individuals at risk of bone thinning.\n\n4. Growth Support in Children & Adolescents\n\nHelps in healthy skeletal development during growth phases.\n\n5. Pregnancy & Lactation (Under Medical Advice)\n\nSupports increased calcium requirements during pregnancy and breastfeeding.\n\n6. Post-Menopausal Bone Support\n\nHelps counteract calcium loss associated with hormonal changes.\n\n7. Muscle & Nerve Function\n\nCalcium plays a critical role in muscle contraction and nerve transmission.\n\nKey Benefits of FABRICAL LIPO SYRUP\n1. Superior Absorption\n\nLiposomal delivery improves bioavailability compared to standard calcium supplements.\n\n2. Targeted Calcium Utilization\n\nVitamin K2-7 ensures calcium is directed to bones rather than soft tissues.\n\n3. Bone Strength & Density\n\nRegular use supports improved bone mineralization.\n\n4. Cardiovascular Safety Support\n\nVitamin K2-7 may help prevent arterial calcification.\n\n5. Gentle on the Stomach\n\nLiposomal calcium is less likely to cause digestive discomfort.\n\n6. Immune Support\n\nVitamin D2 contributes to immune system health.\n\n7. Suitable for All Age Groups\n\nFrom growing children to elderly individuals, this syrup supports lifelong bone care.\n\nRecommended Dosage\n\nDosage should be taken as advised by a healthcare professional. Typically, the syrup may be taken once or twice daily after meals for better absorption.\n\nShake well before use.\n\nPossible Side Effects\n\nFABRICAL LIPO SYRUP is generally well tolerated when taken as directed. However, excessive intake or sensitivity to ingredients may cause:\n\nMild gastrointestinal discomfort\n\nNausea\n\nConstipation\n\nBloating\n\nRare allergic reactions\n\nExcessive calcium intake may lead to hypercalcemia (high calcium levels), which can cause symptoms such as weakness, confusion, or kidney issues. Always follow recommended dosage and consult a healthcare provider before starting supplementation, especially if you have kidney disease, heart conditions, or are taking blood thinners.\n\nPrecautions\n\nDo not exceed recommended dosage.\n\nConsult a doctor if pregnant, breastfeeding, or on medication.\n\nIndividuals with kidney stones or hypercalcemia should seek medical advice before use.\n\nKeep out of reach of children.\n\nStore in a cool, dry place away from direct sunlight.\n\nWhy Choose FABRICAL LIPO SYRUP?\n\nModern lifestyles, inadequate sun exposure, processed diets, and aging can all contribute to weakened bones and poor calcium metabolism. FABRICAL LIPO SYRUP addresses these concerns with advanced liposomal technology and a scientifically balanced combination of calcium, Vitamin K2-7, and Vitamin D2.\n\nUnlike traditional calcium supplements that may be poorly absorbed or cause digestive discomfort, FABRICAL LIPO SYRUP is designed for enhanced bioavailability and better physiological utilization.\n\nIt is not just a calcium supplement — it is a comprehensive bone health solution.\n\nConclusion\n\nFABRICAL LIPO SYRUP is a next-generation calcium supplement formulated with liposomal technology and enriched with Vitamin K2-7 and Vitamin D2 to ensure optimal absorption and proper calcium distribution. By supporting bone density, improving calcium metabolism, and promoting cardiovascular health, it provides a complete approach to skeletal wellness.", "price": 192.0, "discountamount": 58.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2172, "imageuri": "https://productimages.withfloats.com/actual/68b6d8954d1092feddfacbc5.png", "tileimageuri": "https://productimages.withfloats.com/tile/68b6d8954d1092feddfacbc5.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-09-02T11:44:18.672Z", "updatedon": "2026-05-25T06:12:07.885Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//liposomal-calcium-absorption-with-vitamin-k2-7-and-vitamin-d2-syrup/2172", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "FABRICAL LIPO SYRUP", "category": "GENERAL RANGE", "tags": [ "Liposomal Calcium", "liposomal calcium syrup uses", "liposomal calcium syrup benefits", "liposomal calcium syrup dosage", "liposomal calcium syrup for bones", "liposomal calcium syrup for adults", "liposomal calcium syrup for kids", "liposomal calcium syrup absorption", "liposomal calcium syrup side effects", "liposomal calcium syrup for osteoporosis", "liposomal calcium syrup for calcium deficiency", "what is liposomal calcium syrup", "how liposomal calcium syrup works", "is liposomal calcium syrup better than tablets", "when to take liposomal calcium syrup", "who should take liposomal calcium syrup", "liposomal calcium syrup price in india", "best liposomal calcium syrup", "liposomal calcium syrup manufacturer india", "liposomal calcium syrup supplier", "liposomal calcium syrup pharma company", "liposomal calcium syrup wholesale", "calcium liposomal syrup", "liposomal calcium oral syrup", "liquid liposomal calcium", "liposomal calcium supplement syrup", "liposomal calcium with vitamin d syrup", "liposomal calcium brands in india", "what is liposomal calcium", "liposomal calcium tablet", "liposomal calcium supplement" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "683d8fd4990bc014137527ef", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "MULTIVITAMIN, MULTI MINERAL PROTEIN POWDER WITH CHOLINE", "description": "STERIMMUNE HEPA PROTEIN POWDER is a scientifically formulated nutritional supplement designed to support overall wellness, energy, and liver function. Enriched with essential multivitamins, vital minerals, high-quality protein, and choline, this powder provides a balanced solution to meet daily nutritional needs. Ideal for individuals recovering from illness, with weakened immunity, or seeking a daily health boost, it contributes to enhanced vitality and supports organ health—particularly liver health.\n\nKey Ingredients\nMultivitamins: Includes a broad spectrum of vitamins such as A, B-complex, C, D, and E that support immune health, metabolism, vision, and energy production.\n\nMulti Minerals: Essential minerals like calcium, magnesium, zinc, selenium, and iron help in strengthening bones, oxygen transport, antioxidant defense, and enzymatic functions.\n\nProtein: High-quality protein helps in muscle repair, tissue regeneration, and maintaining lean body mass.\n\nCholine: An essential nutrient that plays a critical role in liver function, brain development, nerve function, and fat metabolism.\n\nKey Benefits\nProvides complete nutritional support for the body’s daily needs\n\nPromotes healthy immune system function\n\nSupports liver health and helps improve fat metabolism\n\nEnhances muscle recovery and energy production\n\nImproves cognitive function and memory through the action of choline\n\nSupports antioxidant activity to combat oxidative stress\n\nIdeal for recovery from chronic illness or surgery\n\nSuitable for all age groups including growing children, adults, and the elderly\n\nHow Does It Work?\nSTERIMMUNE HEPA PROTEIN POWDER works by replenishing essential nutrients that may be deficient due to poor diet, illness, or increased physiological demand.\n\nThe multivitamins and minerals help activate numerous biological processes including enzyme function, energy release, and immune defense.\n\nProtein aids in muscle growth, cellular repair, and maintaining body structure.\n\nCholine supports liver detoxification, helps prevent fat accumulation in the liver, and improves neurotransmitter activity.\n\nThe synergistic effect of these ingredients ensures optimal absorption and utilization, keeping the body nourished and resilient.\n\nDirections for Use\nMix one or two tablespoons (approx. 15–30g) of the powder with 200 ml of lukewarm milk or water.\n\nStir well until completely dissolved and consume immediately.\n\nTake once or twice daily, or as directed by a healthcare professional.\n\nCan be consumed with breakfast or between meals for best results.\n\nSide Effects\nSTERIMMUNE HEPA PROTEIN POWDER is generally well tolerated when taken as directed. However, mild side effects may occur in sensitive individuals such as:\n\nBloating or gas due to protein digestion\n\nMild nausea if taken on an empty stomach\n\nAllergic reaction in individuals sensitive to any ingredient (consult label)\n\nAlways consult your physician before starting any supplement, especially if you are pregnant, breastfeeding, or have a chronic medical condition.\n\n", "price": 427.0, "discountamount": 129.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": [ "200 ml", "pregnant breastfeeding", "individuals sensitive", "gas due", "sensitive individuals", "healthcare professional", "consume immediately", "completely dissolved", "water stir", "lukewarm milk", "resilient directions", "body nourished", "utilization keeping", "synergistic effect", "deficient due", "age groups", "surgery suitable", "critical role", "broad spectrum", "enhanced vitality", "weakened immunity", "individuals recovering", "balanced solution", "wellness energy", "bodys daily", "chronic illness", "essential nutrient", "ingredient consult label", "poor diet illness", "complete nutritional support", "liver function enriched", "daily health boost", "meet daily nutritional", "chronic medical condition", "replenishing essential nutrients", "mild side effects", "tablespoons approx 1530g", "improves neurotransmitter activity", "increased physiological demand", "growing children adults" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2129, "imageuri": "https://productimages.withfloats.com/actual/683d8fd9ff3655f5a866e74c.png", "tileimageuri": "https://productimages.withfloats.com/tile/683d8fd9ff3655f5a866e74c.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-06-02T11:49:40.984Z", "updatedon": "2026-03-12T10:46:56.991Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//multivitamin-multi-mineral-protein-powder-with-choline/2129", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "STERIMMUNE HEPA PROTEIN POWDER", "category": "GENERAL RANGE", "tags": [ "MULTIVITAMIN, MULTI MINERAL PROTEIN POWDER WITH CHOLINE", "nutritional needs", "immunity", "health boost", "supports organ health", "Multivitamin Multi Mineral Protein Powder with Choline for muscle recovery", "Benefits of multivitamin protein powder with choline", "Multi-mineral protein powder with choline for energy", "Protein powder with multivitamins, minerals, and choline for weight loss", "Choline in protein powder: benefits for liver health", "Buy multivitamin multi-mineral protein powder with choline online", "Multivitamin protein powder with choline price", "Order multivitamin multi-mineral protein powder with choline" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false } ], "hasmoreitems": false, "isapirequest": false, "totalresults": 27, "query": null, "floatingpoint": null }