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{ "products": [ { "_id": "69142bf71d499513a92e5772", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Nicorandil Tablets 5mg", "description": "Nicorandil Tablets 5 mg is a vasodilatory anti-anginal medication widely prescribed for the management and prevention of angina pectoris (chest pain) associated with coronary artery disease (CAD). Angina results from an imbalance between the heart’s oxygen demand and supply due to restricted blood flow in the coronary arteries. Nicorandil offers a dual mechanism of action — acting both as a nitrate-like vasodilator and a potassium channel opener, making it unique among anti-anginal agents.\n\nBy improving oxygen delivery to the myocardium and reducing cardiac workload, Nicorandil 5 mg Tablets provide effective relief from anginal pain and reduce the frequency and severity of ischemic episodes. It is also beneficial in preventing future attacks, improving exercise tolerance, and enhancing the overall quality of life in patients with chronic stable angina.\n\nComposition\n\nEach tablet contains:\n\nNicorandil IP – 5 mg\n\nExcipients – q.s.\n\nNicorandil tablets are available in film-coated form to ensure stability, easy swallowing, and optimal absorption. They are manufactured in compliance with Good Manufacturing Practices (GMP) standards to ensure safety, purity, and efficacy.\n\nPharmacological Action / Mechanism of Action\n\nNicorandil exhibits a dual mechanism that makes it distinct among anti-anginal drugs:\n\nNitrate-Like Effect:\nNicorandil acts as a nitric oxide (NO) donor. Nitric oxide activates guanylate cyclase, increasing cyclic GMP (cGMP) levels in vascular smooth muscle. This leads to relaxation of blood vessels, particularly veins and large arteries, thereby reducing preload and afterload on the heart. This nitrate-like activity lowers myocardial oxygen demand.\n\nPotassium Channel Opening Effect:\nNicorandil opens ATP-sensitive potassium (KATP) channels in vascular smooth muscle, resulting in arteriolar vasodilation. This increases coronary blood flow and improves oxygen supply to ischemic heart tissues.\n\nTogether, these effects reduce cardiac workload, enhance coronary perfusion, and prevent anginal pain by correcting the oxygen supply-demand mismatch in the heart muscle.\n\nUses and Indications\n\nNicorandil Tablets 5 mg are indicated for the treatment and prevention of angina pectoris in adults, particularly:\n\nChronic Stable Angina:\n\nHelps reduce the frequency and severity of chest pain associated with exertion or emotional stress.\n\nProphylaxis of Angina Attacks:\n\nUsed regularly to prevent anginal episodes, especially in patients with known coronary artery disease.\n\nAdjunct Therapy in Ischemic Heart Disease (IHD):\n\nCan be used alongside beta-blockers, calcium channel blockers, or antiplatelet drugs for enhanced symptom control and long-term protection.\n\nImprovement of Exercise Tolerance:\n\nReduces the likelihood of anginal pain during physical activity, enabling patients to perform daily tasks comfortably.\n\nIn some clinical cases, Nicorandil is also considered for post-myocardial infarction recovery, as it improves coronary perfusion, although this is at the discretion of a cardiologist.\n\nDosage and Administration\n\nRecommended Starting Dose: 5 mg to 10 mg twice daily.\n\nMaintenance Dose: May be increased gradually to 10–20 mg twice daily, depending on clinical response and tolerance.\n\nThe tablets should be swallowed whole with water, preferably at the same times each day.\n\nNicorandil should not be stopped abruptly; dosage tapering is recommended to avoid rebound angina.\n\nAlways follow the dosage instructions provided by the physician.\n\nKey Benefits\n\nDual Mechanism for Comprehensive Relief:\nCombines nitrate-like and potassium channel-opening properties for both arterial and venous dilation, providing superior protection against anginal attacks.\n\nImproves Coronary Blood Flow:\nDilates coronary arteries, increasing oxygen delivery to ischemic myocardial tissues.\n\nReduces Cardiac Workload:\nBy decreasing preload (venous return) and afterload (arterial resistance), Nicorandil minimizes the heart’s oxygen consumption.\n\nRapid Onset of Action:\nNicorandil acts within a short duration, offering quick relief from anginal discomfort.\n\nPrevents Future Angina Episodes:\nRegular use helps maintain steady control of chest pain, improving exercise capacity and quality of life.\n\nCompatible with Other Cardiac Medications:\nCan be safely used alongside antiplatelet agents, beta-blockers, ACE inhibitors, and statins as part of comprehensive cardiac care.\n\nFavorable Safety Profile:\nCompared to nitrates, Nicorandil carries a lower risk of tolerance development, making it suitable for long-term therapy.\n\nEnhances Myocardial Protection:\nNicorandil’s KATP channel activation provides additional cardioprotective effects by improving microvascular blood flow and limiting ischemic damage during stress.\n\nPrecautions and Warnings\n\nAlthough Nicorandil is generally well-tolerated, certain precautions are advised:\n\nHypotension:\nNicorandil may cause a drop in blood pressure due to vasodilation. Caution is advised in patients with hypotension or dehydration.\n\nConcurrent Use with Nitrates:\nShould not be used together with other nitrate medications to avoid severe hypotension.\n\nOral or Gastrointestinal Ulcers:\nRarely, Nicorandil may cause ulcerations in the mouth, intestines, or skin. Treatment should be discontinued if ulceration occurs.\n\nPatients with Low Blood Volume:\nUse cautiously in individuals with hypovolemia or those on diuretics.\n\nDriving and Machinery:\nDizziness or light-headedness may occur; avoid driving until effects are known.\n\nPregnancy and Lactation:\nShould be used only if prescribed by a physician when the potential benefits outweigh the risks.\n\nPossible Side Effects\n\nNicorandil is generally safe but may cause some side effects, particularly at the start of therapy or with higher doses. Common and rare adverse reactions include:\n\nCommon Side Effects:\n\nHeadache (due to vasodilation)\n\nFlushing or warmth sensation\n\nDizziness or light-headedness\n\nNausea or mild stomach upset\n\nFatigue or weakness\n\nLess Common / Rare Side Effects:\n\nHypotension (low blood pressure)\n\nPalpitations or tachycardia\n\nMouth ulcers, anal ulcers, or skin ulceration (uncommon but serious — discontinue if occurs)\n\nRash or allergic reaction\n\nVisual disturbances (rare and usually reversible)\n\nIf any severe reaction or persistent discomfort occurs, medical attention should be sought promptly.\n\nDrug Interactions\n\nAvoid concomitant use with nitrates or phosphodiesterase type-5 inhibitors (e.g., Sildenafil, Tadalafil), as it may cause a dangerous fall in blood pressure.\n\nCaution with antihypertensive drugs or diuretics, which may enhance hypotensive effects.\n\nAlcohol consumption can potentiate dizziness or hypotension and should be limited.\n\nStorage and Handling\n\nStore below 30°C, protected from moisture and direct sunlight.\n\nKeep out of reach of children.\n\nDo not use tablets past the expiry date or if the packaging is damaged.\n\nConclusion\n\nNicorandil Tablets 5 mg offer a modern and effective approach to managing angina pectoris, providing reliable relief through their dual-action mechanism. By combining nitrate-like vasodilation with potassium channel opening, Nicorandil ensures both oxygen supply improvement and reduction of cardiac workload — the cornerstone of angina management.\n\nIt is well-tolerated, fast-acting, and suitable for long-term therapy, making it a preferred choice for patients with chronic stable angina. Regular use under medical supervision helps reduce the frequency of chest pain, improve physical endurance, and enhance the overall quality of life in individuals with coronary artery disease.", "price": 381.0, "discountamount": 115.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2202, "imageuri": "https://productimages.withfloats.com/actual/69142c03b53db80943abd33d.png", "tileimageuri": "https://productimages.withfloats.com/tile/69142c03b53db80943abd33d.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-12T06:40:55.795Z", "updatedon": "2025-12-09T05:59:32.564Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/nicorandil-tablets-5mg/2202", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MAYORANDIL 5 ", "category": "CARDIOLOGYRANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6914248e8c1ae64991df6fc2", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Paracetamol Infusion ip", "description": "Paracetamol Infusion IP is a sterile, non-pyrogenic, and clear solution of Paracetamol (Acetaminophen) formulated for intravenous administration. It is primarily used for the management of pain and fever when oral or rectal routes are not suitable, such as in hospitalized or post-operative patients. Recognized as one of the most widely used analgesic and antipyretic medications, Paracetamol Infusion IP offers rapid onset of action, consistent therapeutic effects, and excellent patient tolerance.\n\nThis formulation ensures precise and controlled delivery of Paracetamol directly into the bloodstream, allowing for faster relief and improved bioavailability compared to oral administration.\n\nComposition\n\nEach 100 mL of Paracetamol Infusion IP typically contains:\n\nParacetamol IP – 1000 mg (1% w/v)\n\nExcipients – as required for stability and isotonicity\n\nWater for Injection – q.s. to 100 mL\n\nThe infusion is usually supplied in ready-to-use glass or plastic bottles or flexible bags, ensuring sterility and ease of use in hospital settings.\n\nMechanism of Action\n\nParacetamol (acetaminophen) exerts its therapeutic effects primarily through central inhibition of prostaglandin synthesis. Unlike nonsteroidal anti-inflammatory drugs (NSAIDs), Paracetamol has minimal peripheral anti-inflammatory activity, making it a safer option for patients with gastrointestinal or platelet-related concerns.\n\nThe drug acts by:\n\nInhibiting the cyclooxygenase (COX) enzymes, particularly COX-3, within the central nervous system, thereby reducing the synthesis of prostaglandins responsible for fever and pain.\n\nModulating the endocannabinoid system and serotonergic pathways, enhancing its analgesic potential.\n\nAs a result, Paracetamol Infusion IP provides effective fever reduction (antipyretic) and pain relief (analgesic) without significant gastrointestinal irritation or bleeding risks.\n\nIndications and Uses\n\nParacetamol Infusion IP is indicated for:\n\nManagement of Fever (Pyrexia):\n\nReduces elevated body temperature in adults and children.\n\nSuitable for patients unable to take oral medication due to nausea, vomiting, or unconsciousness.\n\nRelief of Mild to Moderate Pain:\n\nEffective in conditions like headaches, dental pain, menstrual cramps, and musculoskeletal pain.\n\nCommonly used as part of multimodal pain management after surgical procedures.\n\nPost-Operative and Trauma Pain:\n\nProvides fast, reliable pain relief in surgical recovery and trauma cases where oral medication is not feasible.\n\nAdjunct Therapy:\n\nCan be used alongside opioids to enhance analgesic effect and reduce opioid requirements.\n\nDosage and Administration\n\nAdults and adolescents (>50 kg): 1 g every 6 hours, not exceeding 4 g per day.\n\nAdults and adolescents (<50 kg): Dose adjusted based on body weight, typically 15 mg/kg every 6 hours.\n\nChildren (≥10 kg): 15 mg/kg per dose every 6 hours.\n\nThe infusion should be administered over 15 minutes, using aseptic technique. Paracetamol Infusion should not be mixed with other drugs in the same IV line unless compatibility is established.\n\nKey Benefits\n\nRapid Onset of Action:\nIntravenous administration ensures faster absorption and onset of relief compared to oral or rectal forms.\n\nHigh Bioavailability:\nSince it bypasses gastrointestinal metabolism, almost the entire dose reaches systemic circulation, providing consistent therapeutic effect.\n\nConvenience in Critical Care:\nIdeal for patients who are unconscious, post-surgery, or unable to tolerate oral medications.\n\nSafe and Well-Tolerated:\nHas minimal gastrointestinal side effects and no significant effect on platelets or renal function when used within the recommended dose range.\n\nEffective Multimodal Pain Relief:\nEnhances pain control when combined with opioids, allowing reduced opioid dosage and minimizing associated risks.\n\nStable Formulation:\nThe isotonic and sterile composition ensures patient safety, stability, and reduced risk of contamination.\n\nSuitable for Broad Patient Demographics:\nCan be used in adults, elderly patients, and children under proper medical supervision.\n\nPrecautions and Warnings\n\nWhile Paracetamol Infusion IP is generally safe, the following precautions should be observed:\n\nLiver Impairment:\nUse with caution in patients with hepatic insufficiency, chronic alcoholism, or pre-existing liver disease, as Paracetamol is primarily metabolized in the liver.\n\nRenal Impairment:\nDosage adjustment may be required in severe renal dysfunction.\n\nAvoid Overdose:\nExceeding the recommended dose can lead to severe liver toxicity and, in extreme cases, hepatic failure.\n\nDrug Interactions:\nConcomitant use with other Paracetamol-containing medications increases risk of overdose.\nCaution when used with hepatotoxic drugs or alcohol.\n\nPregnancy and Lactation:\nGenerally considered safe when used under medical supervision, though benefits should outweigh potential risks.\n\nPossible Side Effects\n\nAlthough rare and usually mild, Paracetamol Infusion IP may cause:\n\nAllergic Reactions:\nSkin rash, itching, urticaria, or swelling.\n\nHypotension:\nA transient drop in blood pressure may occur during infusion in some patients.\n\nLiver Toxicity:\nOverdose or prolonged use can lead to hepatocellular injury or elevated liver enzymes.\n\nInjection Site Reactions:\nMild pain, redness, or inflammation at the infusion site.\n\nBlood Disorders (Very Rare):\nThrombocytopenia or leukopenia may occur in extremely rare cases.\n\nIf any severe reaction such as jaundice, persistent vomiting, or allergic swelling occurs, medical attention should be sought immediately.\n\nStorage and Handling\n\nStore below 30°C, protected from light and freezing.\n\nDo not use if the solution appears cloudy or contains particles.\n\nSingle-use only; discard any unused portion after opening.\n\nConclusion\n\nParacetamol Infusion IP stands as a trusted, fast-acting, and safe intravenous formulation of one of the most widely used analgesic and antipyretic agents worldwide. Its ability to deliver rapid and predictable pain and fever relief makes it invaluable in hospitals, emergency care, and post-surgical settings.\n\nWith its favorable safety profile, high efficacy, and compatibility with multimodal pain management strategies, Paracetamol Infusion IP continues to be a first-line choice for clinicians seeking a reliable and well-tolerated solution for pain and fever management.", "price": 225.0, "discountamount": 68.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2200, "imageuri": "https://productimages.withfloats.com/actual/6914248ff448eb2e5cf3b164.png", "tileimageuri": "https://productimages.withfloats.com/tile/6914248ff448eb2e5cf3b164.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-12T06:09:18.258Z", "updatedon": "2025-12-09T05:59:57.8Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/paracetamol-infusion-ip/2200", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "METAPECT 1% W/V ", "category": "GENERAL RANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "689dc838bf323e16334fe2f6", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Rosehip Extract, Devil's Claw Extract & Boswellia Serrata Extract Tablets", "description": "CHONDROFLEX TRIO is a premium joint support supplement formulated to enhance joint health, flexibility, and mobility. It combines the synergistic effects of three powerful natural extracts: Rosehip Extract, Devil's Claw Extract, and Boswellia Serrata Extract. These ingredients are traditionally known for their anti-inflammatory, analgesic, and antioxidant properties, which collectively help to reduce joint pain, swelling, stiffness, and improve overall musculoskeletal wellness. This formulation is designed to aid those experiencing joint discomfort due to arthritis, osteoarthritis, or other degenerative joint conditions, supporting healthy joint function and promoting greater ease of movement.\nWhat is CHONDROFLEX TRIO?\n\nCHONDROFLEX TRIO is a tablet that contains a unique blend of natural extracts — Rosehip Extract, Devil's Claw Extract, and Boswellia Serrata Extract — formulated to target joint inflammation and pain. These extracts work together to protect cartilage, reduce joint inflammation, and support the repair of joint tissues. The supplement aims to improve joint flexibility and enhance overall joint health, making it suitable for individuals dealing with arthritis or age-related joint issues.\nUses of CHONDROFLEX TRIO\nSupports joint health and flexibility\n\nHelps reduce joint inflammation and swelling\nAlleviates joint pain and stiffness\nPromotes cartilage repair and regeneration\nImproves blood supply to the joints, enhancing nutrient delivery\n\nSupports overall musculoskeletal comfort and mobility\nMay aid in managing symptoms related to osteoarthritis and rheumatoid arthritis\nHelps maintain fluid balance within joints for better movement\nSide Effects of CHONDROFLEX TRIO\n\nWhile CHONDROFLEX TRIO is generally well tolerated, some individuals may experience the following side effects:\n\nMild gastrointestinal discomfort such as nausea, diarrhea, or constipation\nAllergic reactions including skin rashes, itching, or swelling (rare)\nPossible sensitivity reactions in some individuals, requiring discontinuation\nIt is important to consult with a healthcare provider if any side effects persist or worsen.\nPrecautions Before Using CHONDROFLEX TRIO\nConsult a healthcare professional before starting if you are pregnant or breastfeeding\nInform your doctor if you have any pre-existing medical conditions, especially liver or kidney disorders\n\nUse caution if you have a history of allergies to herbal supplements\n\nDo not exceed the recommended dosage without medical advice\nKeep out of reach of children\nStore in a cool, dry place away from direct sunlight.\n\nDrug Interactions — What Drugs Interact with CHONDROFLEX TRIO?\n\nCHONDROFLEX TRIO may interact with certain medications, so it is essential to inform your healthcare provider about all medications you are taking before starting this supplement. Potential interactions include:\n\nBlood thinners (anticoagulants), as some ingredients may affect blood clotting\n\nAnti-inflammatory drugs or pain relievers, which may enhance or alter effect\n\nImmunosuppressant drugs, due to potential immune system modulation\n\nDiabetes medications, as some herbal components might influence blood sugar levels\n\nAlways seek professional guidance to avoid adverse effects related to drug interactions.\n\n \n\nConclusion\n\nCHONDROFLEX TRIO, with its potent blend of Rosehip Extract, Devil's Claw Extract, and Boswellia Serrata Extract, offers a natural and effective approach to managing joint health. By reducing inflammation, promoting cartilage repair, and enhancing joint flexibility, it provides relief from discomfort associated with various joint conditions. Regular use combined with medical supervision can contribute to improved joint function and overall quality of life. This supplement is a valuable choice for those seeking a natural alternative to support their joint wellness and mobility.", "price": 560.0, "discountamount": 300.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2160, "imageuri": "https://productimages.withfloats.com/actual/689dc83c6a07538a7ce8bd8c.png", "tileimageuri": "https://productimages.withfloats.com/tile/689dc83c6a07538a7ce8bd8c.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-08-14T11:27:52.965Z", "updatedon": "2025-12-12T07:34:49.928Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/Tablets/2160", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CHONDROFLEX TRIO", "category": "ORTHOPEDICS RANGE", "tags": [ "Rosehip Extract", "stiffness" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6864fe81c4418d1ebb0d08eb", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Dry powder inhaler", "description": "The STERIS DPI DEVICE is a modern, user-friendly Dry Powder Inhaler (DPI) designed to deliver respiratory medication directly to the lungs in a highly efficient and portable form. Inhalation therapy plays a critical role in the management of chronic respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). The DPI device simplifies this process by delivering the drug in the form of a dry powder without the need for coordination between actuation and inhalation, making it ideal for patients of all ages.\n\nWhat is a DPI Device?\nA Dry Powder Inhaler (DPI) is a medical device used to deliver therapeutic medication directly into the lungs. Unlike traditional inhalers that use propellants to push the drug into the lungs, DPI devices rely on the patient’s own inhalation power to disperse and inhale the powdered drug effectively. Essentially, a DPI device is a tool that administers medication in dry powder form to the lungs, providing quick and targeted respiratory relief.\n\nDPI Full Form: Dry Powder Inhaler\n\nUses of STERIS DPI DEVICE\nThe STERIS DPI DEVICE is commonly used in the treatment and management of respiratory diseases such as:\n\nAsthma\n\nChronic Obstructive Pulmonary Disease (COPD)\n\nBronchitis\n\nAllergic airway conditions\n\nIt helps deliver medication directly to the airways, ensuring faster action and reduced systemic side effects compared to oral treatments.\n\nHow It Works\nWhen the patient inhales through the mouthpiece, the device uses the airflow to disperse the dry powder into fine particles, allowing it to reach deep into the lungs. The inhaled medication begins working quickly to open airways, reduce inflammation, or treat infection, depending on the formulation used with the DPI.\n\nSide Effects of Dry Powder Inhaler Use\nWhile the STERIS DPI DEVICE itself is safe and user-friendly, some medications delivered via DPI may cause minor side effects such as:\n\nDry throat or mouth\n\nHoarseness\n\nCough\n\nIrritation in the throat\n\nFungal infections in the mouth (if corticosteroids are used and mouth is not rinsed after use)\n\nThese side effects can often be minimized with proper usage and hygiene.\n\nPrecautions Before Using STERIS DPI DEVICE\nAlways read the instructions carefully before first-time use.\n\nMake sure the device is clean and free from moisture.\n\nInhale deeply and forcefully to ensure proper medication delivery.\n\nDo not exhale into the device, as moisture can affect the powder's consistency.\n\nStore in a dry, cool place away from direct sunlight.\n\nAlways rinse your mouth after using corticosteroid-based powders.\n\nAdvantages of STERIS DPI DEVICE\nPropellant-free and eco-friendly\n\nPortable and compact design for daily use\n\nNo coordination required between inhalation and actuation\n\nDelivers medication effectively with minimal effort\n\nEasy-to-use, even for elderly or pediatric patients\n\nConclusion\nThe STERIS DPI DEVICE is a highly effective solution for individuals suffering from chronic or acute respiratory disorders. By delivering medication directly to the lungs in a dry powder form, it ensures fast relief, greater bioavailability, and improved patient compliance. Whether you’re managing asthma or COPD, this DPI device offers a dependable and convenient way to breathe easier every day.", "price": 255.0, "discountamount": 77.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": [ "coordination required", "inhalation power", "inhalation making", "breathe easier", "individuals suffering", "compact design", "ecofriendly portable", "direct sunlight", "instructions carefully", "hygiene precautions", "proper usage", "medications delivered", "reach deep", "oral treatments", "critical role", "medical device", "patient inhales", "administers medication", "highly efficient", "respiratory diseases", "dpi device", "dry throat", "dry powder", "side effects", "moisture inhale deeply", "delivering medication directly", "lungs providing quick", "dry powder form", "chronic respiratory conditions", "pediatric patients conclusion", "dpi device offers", "dpi device simplifies", "steris dpi device", "dpi side effects", "youre managing asthma", "dry powder inhaler", "minor side effects", "improved patient compliance", "highly effective solution", "throat fungal infections", "dry cool place", "acute respiratory disorders", "minimal effort easytouse", "corticosteroidbased powders advantages", "powders consistency store", "treat infection depending", "fine particles allowing" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2142, "imageuri": "https://productimages.withfloats.com/actual/6864feb4c75fa610aeaeaeda.png", "tileimageuri": "https://productimages.withfloats.com/tile/6864feb4c75fa610aeaeaeda.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-07-02T09:40:17.078Z", "updatedon": "2025-12-02T07:19:43.885Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/dry-powder-inhaler/2142", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "STERIS DPI DEVICE", "category": "RESPIRTORYRANGE", "tags": [ "Dry powder inhaler", "pulmonary disease (COPD)", "respiratory symptoms", "Asthma", "Asthma or COPD Patients" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6827200ed43a11f501af2c5f", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Nifedipine 5mg", "description": "NIFEDULES 5 is a prescription medication containing Nifedipine 5mg, a well-known calcium channel blocker used to manage high blood pressure (hypertension), angina (chest pain), and other cardiovascular conditions. It works by improving blood flow and reducing the workload on the heart, offering reliable relief and long-term management of heart-related symptoms. NIFEDULES 5 helps maintain a healthy cardiovascular system and prevents complications associated with high blood pressure.\n\nKey Ingredient\nNifedipine 5mg\nNifedipine belongs to the class of medications known as dihydropyridine calcium channel blockers. It is effective in dilating blood vessels, improving circulation, and reducing the heart’s effort in pumping blood.\n\nKey Benefits\nHelps control and lower high blood pressure\n\nRelieves chronic stable angina and variant angina\n\nImproves oxygen delivery to the heart\n\nPrevents chest pain during physical or emotional stress\n\nReduces the risk of stroke and heart attack\n\nSupports better heart function and circulation\n\nOffers rapid onset of action in certain formulations\n\nHow Does It Work?\nNIFEDULES 5 works by inhibiting the influx of calcium ions into the smooth muscles of the heart and blood vessels. By blocking calcium entry, it causes relaxation of the vascular smooth muscles, resulting in the dilation of arteries. This leads to decreased vascular resistance, improved blood flow, and reduced blood pressure. For angina patients, it decreases the oxygen demand of the heart, helping prevent chest pain.\n\nDirections for Use\nTake the medication exactly as prescribed by your doctor\n\nUsually taken orally with or without food\n\nSwallow the tablet whole with water; do not crush or chew\n\nFollow a consistent schedule daily to maintain steady drug levels\n\nDo not abruptly stop the medication without consulting your healthcare provider\n\nSide Effects\nHeadache\n\nFlushing (warmth, redness in face or neck)\n\nDizziness or light-headedness\n\nSwelling in the ankles or feet\n\nNausea or upset stomach\n\nRapid heartbeat or palpitations\n\nFatigue or weakness\n\nRare but serious: low blood pressure, severe chest pain, or allergic reaction\n\n", "price": 28.0, "discountamount": 9.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": [ "prescription medication", "allergic reaction", "weakness rare", "palpitations fatigue", "feet nausea", "lightheadedness swelling", "neck dizziness", "abruptly stop", "chew follow", "food swallow", "oxygen demand", "angina patients", "smooth muscles", "heart function", "hearts effort", "prevents complications", "longterm management", "nifedipine 5mg", "nifedules 5nifedules 5", "calcium ions", "cardiovascular conditions", "blood vessels", "heart attack supports", "blocking calcium entry", "healthy cardiovascular system", "reduced blood pressure", "improving blood flow", "consistent schedule daily", "emotional stress reduces" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2115, "imageuri": "https://productimages.withfloats.com/actual/68272010de3c95a1760cd413.png", "tileimageuri": "https://productimages.withfloats.com/tile/68272010de3c95a1760cd413.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-05-16T11:22:54.123Z", "updatedon": "2025-12-08T09:03:50.931Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/nifedipine-5mg/2115", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Steris Healthcare Pvt Ltd", "category": "CARDIOLOGYRANGE", "tags": [ "Nifedipine 5mg Price", "Nifedipine dosage", "Nifedipine 5mg Uses in Hindi", "Nifedipine 5mg uses" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "681b331b233d4ecb404fe2d7", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Isosorbide Mononitrate 10 mg", "description": "CARDULES ISMN 10 is a prescription medication formulated to effectively manage and prevent angina pectoris (chest pain) associated with coronary artery disease. This medicine contains Isosorbide Mononitrate (10 mg), a long-acting nitrate that helps reduce the frequency and severity of anginal episodes. It is commonly prescribed as part of a long-term treatment plan for individuals with stable angina and other cardiovascular conditions to improve heart efficiency and blood flow.\n\nKey Ingredients\nIsosorbide Mononitrate 10 mg\nIsosorbide Mononitrate is the active nitrate component in this medicine, known for its vasodilatory effects that relax blood vessels and ease the heart’s workload. It is a metabolite of isosorbide dinitrate and offers longer-lasting therapeutic benefits with fewer doses.\n\nKey Benefits\nPrevents Chest Pain (Angina): CARDULES ISMN 10 is effective in reducing the number and severity of angina attacks by improving blood flow to the heart muscle.\n\nImproves Blood Circulation: The vasodilatory action of Isosorbide Mononitrate widens the arteries and veins, facilitating better circulation and oxygen delivery.\n\nReduces Heart Workload: By dilating blood vessels, the medication decreases the heart's oxygen demand, allowing it to function more efficiently.\n\nEnhances Exercise Tolerance: Patients using this medication often experience an increase in exercise capacity, as the risk of angina during physical activity is significantly reduced.\n\nLong-Acting Relief: As a sustained nitrate, CARDULES ISMN 10 provides long-lasting protection against anginal attacks when taken regularly.\n\nHow Does It Work?\nIsosorbide Mononitrate works by releasing nitric oxide in the smooth muscle cells of blood vessels. This nitric oxide activates an enzyme called guanylate cyclase, which increases cyclic guanosine monophosphate (cGMP). The rise in cGMP levels leads to the relaxation of vascular smooth muscles, causing vasodilation. This process reduces the amount of work the heart must do and lowers myocardial oxygen consumption. As a result, blood flows more easily, and the frequency of chest pain episodes is reduced. This mechanism makes CARDULES ISMN 10 a highly effective drug in the prevention of angina.\n\nDirections for Use\nTake CARDULES ISMN 10 strictly as prescribed by your doctor.\nIt is typically taken once or twice daily, depending on the severity of the condition and the prescribing physician's guidance.\nSwallow the tablet whole with a glass of water, preferably on an empty stomach or as directed.\nDo not crush, chew, or break the tablet, as it may interfere with the drug’s effectiveness.\nFor best results, take it at the same time each day to maintain consistent blood levels.\nAvoid abrupt discontinuation of the medication unless advised by your healthcare provider.\n\nSide Effects\nWhile CARDULES ISMN 10 is generally well-tolerated, some individuals may experience side effects, especially when starting treatment or adjusting dosage. Common and less serious side effects include:\n\nHeadache\n\nDizziness or light-headedness\n\nFlushing (warmth, redness, or tingly feeling under the skin)\n\nNausea\n\nFatigue\n\nIn rare cases, more serious side effects may occur, such as:\n\nSevere hypotension (low blood pressure)\n\nFainting\n\nIrregular heartbeat\n\nAllergic reactions like rash, itching, or swelling\n\nIf any severe or unusual side effects occur, seek immediate medical attention. Regular monitoring and dose adjustments may help manage and minimize side effects.", "price": 25.0, "discountamount": 8.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": [ "commonly prescribed", "effectively manage", "angina directions", "medication decreases", "angina attacks", "stable angina", "dose adjustments", "rash itching", "rare cases", "tingly feeling", "headache dizziness", "generally welltolerated", "cardules ismn 10", "drugs effectiveness", "crush chew", "empty stomach", "water preferably", "daily depending", "process reduces", "anginal attacks", "longlasting protection", "physical activity", "exercise capacity", "veins facilitating", "vasodilatory action", "hearts workload", "cardiovascular conditions", "helps reduce", "vasodilatory effects", "starting treatment", "isosorbide dinitrate", "anginal episodes", "longacting nitrate", "side effects", "blood vessels", "experience side effects", "prescription medication formulated", "minimize side effects", "highly effective drug", "improve heart efficiency", "dilating blood vessels", "relax blood vessels", "chest pain episodes", "isosorbide mononitrate widens", "active nitrate component", "longterm treatment plan", "result blood flows", "improving blood flow", "skin nausea fatigue", "adjusting dosage common", "cgmp levels leads", "nitric oxide activates", "smooth muscle cells", "releasing nitric oxide", "coronary artery disease" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2105, "imageuri": "https://productimages.withfloats.com/actual/681b331ec4193dc2e4e9a77a.png", "tileimageuri": "https://productimages.withfloats.com/tile/681b331ec4193dc2e4e9a77a.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-05-07T10:16:59.84Z", "updatedon": "2025-11-25T09:21:15.124Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/isosorbide-mononitrate-10-mg/2105", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Steris Healthcare Pvt. Ltd.", "category": "CARDIOLOGYRANGE", "tags": [ "Isosorbide Mononitrate 10 mg Uses in Hindi", "Isosorbide 10 mg uses", "Isosorbide mononitrate 120 mg" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "681b2e1131166af9fb0be5c3", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Isosorbide Dinitrate 5mg", "description": "CARDULES ISDN 5 is a prescription medication formulated with Isosorbide Dinitrate (5 mg), a well-known nitrate used to prevent and treat chest pain (angina) caused by coronary artery disease. This medicine is commonly prescribed to improve blood flow to the heart and reduce the frequency and severity of anginal attacks. It works by relaxing the blood vessels, making it easier for the heart to pump blood, and reducing its oxygen demand. CARDULES ISDN 5 is especially useful for long-term management of chronic angina and can be an essential part of a comprehensive cardiac care plan.\n\nKey Ingredients\nIsosorbide Dinitrate (5 mg) – This is the active pharmaceutical ingredient in CARDULES ISDN 5. Belonging to the nitrate class of drugs, Isosorbide Dinitrate helps widen and relax blood vessels, thereby improving blood flow and oxygen delivery to the heart muscle.\n\nKey Benefits\nProvides effective relief from angina (chest pain)\n\nHelps prevent angina episodes when taken regularly\n\nImproves blood circulation to the heart\n\nReduces the heart's workload and oxygen demand\n\nSupports overall cardiac function in patients with coronary artery disease\n\nCan improve exercise tolerance and reduce anginal frequency\n\nHow Does It Work?\nCARDULES ISDN 5 works by releasing nitric oxide within the vascular smooth muscle, leading to the relaxation of blood vessels. This vasodilation effect reduces the amount of work the heart must do to pump blood and lowers its oxygen demand. By widening the arteries and veins, Isosorbide Dinitrate facilitates better oxygen delivery to the heart tissue, which helps prevent angina attacks. It is especially effective in preventing episodes when used on a regular schedule, rather than providing immediate relief during an ongoing attack.\n\nDirections for Use\nAlways take CARDULES ISDN 5 exactly as prescribed by your physician.\n\nTypically taken orally, with or without food.\n\nIt is important to take the medication at the same times each day to maintain consistent nitrate levels in the bloodstream.\n\nSwallow the tablet whole with water; do not crush or chew unless advised.\n\nDo not stop the medication abruptly without consulting your doctor, as it may worsen angina symptoms.\n\nSide Effects\nWhile CARDULES ISDN 5 is generally well-tolerated, some individuals may experience side effects. These can include:\n\nHeadache (commonly occurs initially and often subsides with continued use)\n\nDizziness or light-headedness, especially when rising from a sitting or lying position\n\nNausea or vomiting\n\nFlushing or warmth of the skin\n\nLow blood pressure (hypotension)\n\nRapid heartbeat (tachycardia)\n\nIn rare cases, allergic reactions or more serious cardiovascular effects may occur. Always report any persistent or severe side effects to your healthcare provider immediately.\n\n", "price": 8.0, "discountamount": 2.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": [ "effective relief", "heart tissue", "commonly prescribed", "heart reduces", "vomiting flushing", "generally welltolerated", "medication abruptly", "bloodstream swallow", "physician typically", "cardules ismn 5", "regular schedule", "preventing episodes", "cardiac function", "hearts workload", "nitrate class", "essential part", "chronic angina", "longterm management", "wellknown nitrate", "oxygen delivery", "anginal attacks", "pump blood", "cardiovascular effects", "oxygen demand", "blood vessels", "reduce anginal frequency", "oxygen demand supports", "prescription medication formulated", "relax blood vessels", "blood vessels making", "vasodilation effect reduces", "improving blood flow", "improve blood flow", "severe side effects", "experience side effects", "healthcare provider immediately", "lying position nausea", "ongoing attack directions", "releasing nitric oxide", "improve exercise tolerance", "active pharmaceutical ingredient", "coronary artery disease" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2104, "imageuri": "https://productimages.withfloats.com/actual/681b2e1454203247c379193a.png", "tileimageuri": "https://productimages.withfloats.com/tile/681b2e1454203247c379193a.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-05-07T09:55:29.776Z", "updatedon": "2025-11-25T09:21:33.234Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/isosorbide-dinitrate-5mg/2104", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "", "category": "CARDIOLOGYRANGE", "tags": [ "Isosorbide dinitrate 5 mg uses", "Isosorbide dinitrate uses", "Isosorbide Dinitrate 5 mg price", "Isosorbide dinitrate dosage" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "66d6df52731125bdd4e1003b", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "VALGANCICLOVIR TABLET IP 450 MG", "description": "VOLANE SOURCE 450 is a pharmaceutical tablet containing Valganciclovir at a dosage strength of 450 mg. It is a potent antiviral medication primarily designed to treat and prevent certain viral infections caused by cytomegalovirus (CMV), especially in immunocompromised patients such as those undergoing organ transplants or living with HIV/AIDS. Manufactured adhering to strict quality standards under the tablet IP (Indian Pharmacopoeia), VOLANE SOURCE 450 ensures consistent efficacy and safety for patients requiring antiviral therapy.\n\nComposition and Pharmacological Profile\nEach film-coated tablet of VOLANE SOURCE 450 contains 450 mg of Valganciclovir as the active ingredient. Valganciclovir is a prodrug of ganciclovir, meaning it is converted in the body into ganciclovir, which is the active antiviral agent. Its mechanism involves inhibiting viral DNA synthesis by competing with deoxyguanosine triphosphate for incorporation into viral DNA, thereby suppressing the replication of CMV and related herpes viruses.\n\nPrimary Uses of VOLANE SOURCE 450\nTreatment of CMV Retinitis: CMV retinitis is a serious viral eye infection common in patients with weakened immune systems, such as AIDS patients. It leads to inflammation and possible vision loss if left untreated. VOLANE SOURCE 450 is a frontline therapy used to halt the progression of this infection.\n\nPrevention of CMV Disease in Transplant Patients: Solid organ transplant recipients and bone marrow transplant patients are at high risk of CMV infection due to immunosuppressive drugs. Prophylactic use of VOLANE SOURCE 450 helps in preventing CMV disease in these vulnerable groups.\n\nTreatment of CMV Infection: Apart from retinitis, CMV can cause systemic infections affecting multiple organs, including lungs, digestive tract, and nervous system. VOLANE SOURCE 450 is used for managing such infections effectively.\n\nPart of Combination Therapy: It may also be prescribed alongside other antiviral agents as part of combination treatment protocols tailored to complex viral infections, enhancing viral suppression.\n\nKey Benefits of Using VOLANE SOURCE 450\nHigh Oral Bioavailability: Being a prodrug, Valganciclovir is well absorbed orally and converted efficiently to ganciclovir in the body, enabling effective antiviral levels.\n\nWide Spectrum of Action: Targets multiple herpesviruses with high specificity, primarily cytomegalovirus, reducing viral load and infection severity.\n\nReduced Risk of CMV Disease Post-Transplant: By preventing CMV infection in transplant recipients, VOLANE SOURCE 450 significantly lowers the risk of post-transplant complications related to viral disease.\n\nConvenient Oral Dosage: Unlike intravenous ganciclovir, VOLANE SOURCE 450 allows for easier home administration, improving patient compliance and quality of life.\n\nEffective Against Resistant Strains: Used in recurrent and resistant CMV infections, especially where other therapies fail.\n\nProtects Vision: In CMV retinitis patients, prompt use of VOLANE SOURCE 450 can preserve vision and prevent blindness due to viral damage.\n\nRecommended Dosage and Administration\nThe dosing of VOLANE SOURCE 450 depends on the condition being treated, kidney function, and patient immune status. It is typically prescribed by healthcare professionals following careful medical assessment.\n\nFor CMV retinitis treatment, the initial dose is usually higher and then tapered down for maintenance.\n\nFor CMV prophylaxis post-transplant, a standard dose is taken once or twice daily for several months.\n\nIt is advised to swallow tablets whole with food to enhance absorption.\n\nRegular monitoring of blood counts and kidney function is essential during therapy since the drug can impact bone marrow and renal function.\n\nPotential Side Effects of VOLANE SOURCE 450\nLike any potent antiviral medication, VOLANE SOURCE 450 can cause side effects. Awareness and timely reporting to a healthcare provider are important to manage these effects safely.\n\nCommon side effects include:\n\nGastrointestinal symptoms: Nausea, vomiting, diarrhea, and abdominal pain.\n\nBone marrow suppression: Leading to anemia, neutropenia (low neutrophils), or thrombocytopenia (low platelets), which increase infection risks and bruising.\n\nHeadache and fatigue: Mild to moderate headache and tiredness may occur.\n\nFever and infections: Due to immune suppression, secondary infections may arise.\n\nElectrolyte imbalance: Occasionally, abnormalities in blood calcium or potassium levels.\n\nRare hypersensitivity reactions: Skin rash, itching, or swelling which require immediate medical attention.\n\nPrecautions and Contraindications\nPatients with severe renal impairment require dose adjustments or alternative therapies to avoid toxicity.\n\nPregnant or breastfeeding women should avoid this drug due to potential harm to the fetus or infant.\n\nRegular blood tests are necessary to monitor for hematologic or renal side effects.\n\nUse caution in patients with pre-existing neutropenia or anemia.\n\nConclusion\nVOLANE SOURCE 450 (Valganciclovir Tablet IP 450 mg) represents a reliable and efficacious antiviral therapy specifically targeting cytomegalovirus infections. Its role in treatment and prevention of CMV-related diseases, especially among immunocompromised patients, makes it invaluable in clinical practice.\n\nIts oral formulation allows for easy administration and effective drug delivery, improving patient adherence and outcomes. While the risk of side effects exists, careful monitoring and adherence to prescribed dosages minimize complications.\n\nOverall, VOLANE SOURCE 450 offers a potent solution against serious viral infections, helping preserve health, prevent complications, and improve quality of life for vulnerable patient populations.\n\n", "price": 3944.0, "discountamount": 2367.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "viral DNA", "rare cases", "Key Benefits", "CMV Retinitis", "VOLANE SOURCE", "CMV infection", "various organs", "kidney function", "prescribed course", "chain termination", "active ingredient", "organ transplants", "medical condition", "blood cell counts", "healthcare provider", "severe side effects", "Common Side Effects", "Regular blood tests", "complete eradication", "antiviral medication", "high bioavailability", "severe eye infection", "Serious Side Effects", "high-risk individuals", "convenient oral option", "bone marrow suppression", "weakened immune systems", "VALGANCICLOVIR TABLET IP", "High Oral Bioavailability", "Immediate medical attention" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1950, "imageuri": "https://productimages.withfloats.com/actual/6936b55236477d52c1e94700.png", "tileimageuri": "https://productimages.withfloats.com/tile/6936b55236477d52c1e94700.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-09-03T10:05:06.943Z", "updatedon": "2025-12-08T11:24:01.847Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/valganciclovir-tablet-ip-450-mg/1950", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "VOLANE SOURCE 450", "category": "CARDIOLOGYRANGE", "tags": [ "VALGANCICLOVIR TABLET IP 450 MG USUE", "Valganciclovir Tablet IP 450 mg", "infections caused by cytomegalovirus (CMV).", "VOLANE SOURCE 450", "helps control the spread of the CMV infection within the body", "high bioavailability", "improve quality of life for vulnerable patient populations" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6661a73687f0960e14a2c739", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "mycophenolate sodium 360 mg", "description": "MYCOPLASM S 360 \nMycophenolate sodium 360 mg is an essential immunosuppressant medication designed to prevent organ transplant rejection, particularly for kidney, heart, and liver transplants. As the sodium salt of mycophenolic acid, it delivers 360 mg of the active moiety per tablet, providing targeted immune suppression to help patients maintain their new organs long-term. This product stands out for its enteric-coated formulation, which enhances gastrointestinal tolerability compared to other forms, making it a preferred choice in post-transplant care regimens.​\n\nUses of Mycophenolate Sodium 360 mg\nMycophenolate sodium 360 mg primarily serves as a prophylactic agent against acute rejection in adult and pediatric patients receiving allogeneic renal, cardiac, or hepatic transplants. It works alongside other immunosuppressants like cyclosporine and corticosteroids to create a balanced regimen that minimizes the risk of graft loss. Clinically, it proves effective in de novo transplant recipients, where starting therapy early post-surgery significantly reduces rejection episodes. Beyond transplants, off-label applications include managing refractory autoimmune conditions such as lupus nephritis or myasthenia gravis, where immune overactivity damages tissues.​\n\nThe drug targets the proliferation of T- and B-lymphocytes, key players in immune responses that can attack transplanted organs. In renal transplant patients, for instance, it helps preserve kidney function by curbing antibody-mediated rejection. Its role extends to maintenance therapy, where consistent dosing sustains immunosuppression without excessive toxicity. Healthcare providers often adjust it based on patient response and trough levels of the active metabolite, mycophenolic acid (MPA), ensuring optimal therapeutic outcomes.​\n\nKey Benefits of Mycophenolate Sodium 360 mg\nMycophenolate sodium 360 mg offers several advantages that make it a cornerstone in transplant medicine. One primary benefit is its selective inhibition of lymphocyte proliferation, sparing other cell types and reducing broad-spectrum immunosuppression risks. This leads to fewer opportunistic infections compared to older agents like azathioprine. The enteric coating minimizes upper GI upset, improving patient compliance—studies show higher adherence rates with this formulation.​\n\nEnhanced Graft Survival: Prolongs organ viability by effectively suppressing cell-mediated and humoral immunity, with clinical data showing reduced biopsy-proven rejection rates.\n\nImproved Tolerability: Lower incidence of nausea and diarrhea due to delayed-release technology, allowing twice-daily dosing without food restrictions.\n\nFlexible Dosing: Equivalent to 720 mg mycophenolate mofetil, but with predictable MPA exposure via enterohepatic recirculation for steady-state efficacy.\n\nPediatric Suitability: Approved for children over 2 years in renal transplants, supporting growth without compromising safety.\n\nCost-Effective Long-Term Option: Balances efficacy and side effect profile, potentially lowering overall healthcare costs from fewer rejections or hospitalizations.​\n\nPatients experience better quality of life, with sustained energy levels and fewer interruptions from acute rejection crises. Its metabolism to MPA via liver glucuronidation ensures reliable pharmacokinetics, even in patients with mild renal impairment.​\n\nSide Effects of Mycophenolate Sodium 360 mg\nWhile highly effective, mycophenolate sodium 360 mg carries risks typical of immunosuppressants, necessitating vigilant monitoring. Common adverse effects stem from its impact on rapidly dividing cells, particularly in the gut and bone marrow.\n\nCommon Side Effects\nGastrointestinal issues like diarrhea, nausea, vomiting, and abdominal pain, affecting up to 30-50% of users.\n\nHeadache, insomnia, and tremor, often mild and transient.\n\nInfections such as urinary tract or respiratory, due to moderated immunity.\n\nHypertension or peripheral edema, manageable with supportive care.\n\nLeukopenia or anemia, requiring periodic blood counts.​\n\nSerious Side Effects\nSevere myelosuppression leading to neutropenia or thrombocytopenia, which can increase infection or bleeding risks.\n\nProgressive multifocal leukoencephalopathy (PML), a rare brain infection linked to JC virus reactivation.\n\nGastrointestinal perforation or bleeding, especially in at-risk patients.\n\nIncreased malignancy risk, including lymphoma or skin cancers, over long-term use.\n\nHypersensitivity reactions like rash or anaphylaxis.​\n\nRegular complete blood counts, viral monitoring (e.g., CMV, BK virus), and skin exams mitigate these risks. Dose reductions or discontinuation may be needed if counts drop significantly.​\n\nMechanism of Action\nMycophenolate sodium 360 mg rapidly hydrolyzes to mycophenolic acid (MPA), a potent, reversible, non-competitive inhibitor of inosine-5'-monophosphate dehydrogenase (IMPDH). This enzyme catalyzes the rate-limiting step in de novo guanine nucleotide synthesis, depleting guanosine nucleotides essential for T- and B-cell DNA replication. Lymphocytes, reliant on this pathway, undergo proliferation arrest, suppressing both cell-mediated immunity and antibody production.​\n\nMPA also hinders glycosylation of adhesion molecules on lymphocytes and monocytes, impeding their migration to graft sites. It reduces nitric oxide production in macrophages without affecting endothelial cells, curbing inflammation. Enterohepatic recirculation of the glucuronide metabolite (MPAG) prolongs MPA exposure, enhancing efficacy. Protein binding to albumin (around 97%) ensures targeted delivery, with clearance primarily renal for the inactive form.​\n\nDosage and Administration Guidelines\nStandard dosing for renal transplant is 720 mg (two 360 mg tablets) twice daily, starting within 72 hours post-surgery. Adjustments occur for hepatic or cardiac transplants, often alongside cyclosporine. Therapeutic drug monitoring of MPA AUC (area under curve) optimizes levels between 30-60 mcg·h/mL. Take on an empty stomach for best absorption, though food has minimal impact due to the coating.​\n\nPrecautions and Warnings\nAvoid in pregnancy (Category D) due to teratogenicity—use contraception and regular pregnancy tests. Contraindicated in active untreated infections. Monitor for GI bleeding in ulcerative colitis patients. Drug interactions with antacids, cholestyramine, or rifampin alter MPA levels. Live vaccines are prohibited.​\n\nConclusion\nMycophenolate sodium 360 mg represents a vital advancement in transplant immunosuppression, offering robust protection against rejection with a favorable benefit-risk profile. Its targeted action on lymphocytes, combined with improved GI tolerance, empowers patients to thrive post-transplant. By integrating it into comprehensive regimens with close monitoring, healthcare teams maximize graft success and patient well-being. Always consult a specialist for personalized guidance to harness its full potential safely.\nEmail: info@sterispharma.com / contact@sterispharma.com\nCall/WhatsApp: 7877551268, 7849827488\nORDER Now: \nhttps://www.sterisonline.com/product/mycoplasm-s-360-133670\n\n\n\n\n\n\n", "price": 767.0, "discountamount": 567.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "dose", "risk", "body", "part", "ORDER", "360mg", "Email", "cells", "dosage", "nausea", "vomiting", "schedule", "headache", "strength", "WhatsApp", "diarrhea", "activity", "rejection", "treatment", "infections", "supplements", "information", "MYCOPLASM S", "sterispharma", "sterisonline", "stomach pain", "blood counts", "immune system", "complications", "liver problems", "liver function", "other medications", "Regular monitoring", "medical conditions", "healthcare provider", "Common side effects", "Serious side effects", "white blood cell count", "potential drug interactions", "optimal therapeutic effects", "combination therapy regimen", "organ transplant recipients", "Mycophenolate Sodium therapy", "other immunosuppressive drugs" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1474, "imageuri": "https://productimages.withfloats.com/actual/6661a739c749b7962dbc08c6.jpg", "tileimageuri": "https://productimages.withfloats.com/tile/6661a739c749b7962dbc08c6.jpg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-06T12:10:30.488Z", "updatedon": "2025-12-04T07:44:09.122Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//mycophenolate-sodium-360-mg/1474", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MYCOPLASM S 360 ", "category": "Oncology", "tags": [ "MYCOPLASM S 360", "Mycophenolate sodium (360mg)", "Mycophenolate sodium 360 mg price", "Mycophenolate sodium 360 mg brands", "Mycophenolate sodium 360 mg side effects", "Myfortic 360 alternative", "Myfortic 500" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false } ], "hasmoreitems": false, "isapirequest": false, "totalresults": 27, "query": null, "floatingpoint": null }