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"name": "Glimepiride IP1 mg, Voglibose IP 0.2 MG & Metformin Hydrochloride IP 500 mg ",
"description": "GLIMITERIS MV1 0.2 is an advanced fixed-dose combination (FDC) medication designed for adults with Type 2 Diabetes Mellitus (T2DM) who require more than lifestyle modifications or single/dual therapy to maintain optimal blood sugar levels. This innovative formulation brings together the power of three well-established antidiabetic agents—Glimepiride (1 mg), Voglibose (0.2 mg), and Metformin Hydrochloride SR (500 mg)—to provide comprehensive glycemic control.\n\nIt is particularly effective for patients struggling with postprandial hyperglycemia, fasting glucose regulation, and HbA1c reduction, making it a preferred choice in cases of poorly controlled diabetes.\n\n \n\nMechanism of Action\nThe therapeutic benefit of GLIMITERIS MV1 0.2 comes from the unique synergy of its three components, each targeting different aspects of glucose metabolism:\n\n1. Glimepiride (1 mg) – Sulfonylurea\nStimulates insulin secretion by activating pancreatic beta cells.\n\nProvides a long-lasting effect with comparatively lower hypoglycemia risk than older sulfonylureas.\n\nHelps reduce both fasting and postprandial glucose levels.\n\n2. Voglibose (0.2 mg) – Alpha-Glucosidase Inhibitor\nDelays the breakdown and absorption of carbohydrates in the intestine.\n\nMinimizes post-meal glucose spikes (PPBG).\n\nActs locally in the gut and has minimal systemic absorption, which reduces systemic side effects.\n\n3. Metformin Hydrochloride SR (500 mg) – Biguanide\nDecreases hepatic glucose production (gluconeogenesis).\n\nImproves peripheral insulin sensitivity, enhancing glucose uptake in muscles.\n\nDoes not cause hypoglycemia on its own.\n\nThe sustained-release (SR) formulation ensures extended control and reduces gastrointestinal side effects.\n\n \n\nIndications\nGLIMITERIS MV1 0.2 is indicated for:\n\nAdults with Type 2 Diabetes Mellitus.\n\nPatients inadequately controlled with monotherapy or dual therapy.\n\nManagement of fasting and postprandial hyperglycemia.\n\nLong-term HbA1c reduction as part of a comprehensive diabetes care plan.\n\n \n\nKey Benefits\n✅ Comprehensive Blood Sugar Control – Acts on fasting, post-meal, and long-term HbA1c levels.\n✅ Postprandial Spike Management – Voglibose effectively controls carbohydrate-induced sugar surges.\n✅ Reduced Pill Burden – Combines three medicines into a single tablet.\n✅ Lower Hypoglycemia Risk – Metformin and Voglibose balance out Glimepiride’s insulin-secreting effect.\n✅ Weight Management Support – Metformin may promote modest weight loss or prevent weight gain.\n✅ Improved Tolerability – SR formulation of Metformin enhances gastrointestinal comfort.\n\n \n\nDosage and Administration\nRecommended dose: One tablet once or twice daily with meals, or as directed by the physician.\n\nAdministration tips:\n\nTake with the first bite of a main meal to maximize Voglibose’s effect.\n\nSwallow whole with water; do not crush or chew the SR tablet.\n\nDose adjustments: Based on blood sugar monitoring, clinical response, and renal/hepatic function.\n\n \n\nContraindications\nGLIMITERIS MV1 0.2 is not suitable for patients with:\n\nType 1 diabetes or diabetic ketoacidosis.\n\nSevere renal impairment (eGFR <30 mL/min/1.73 m²).\n\nHepatic dysfunction.\n\nSevere gastrointestinal diseases.\n\nHistory of lactic acidosis.\n\nHypersensitivity to Glimepiride, Voglibose, or Metformin.\n\nPregnancy and lactation (unless strictly advised by a physician).\n\n \n\nWarnings and Precautions\nHypoglycemia: Risk is higher when combined with other antidiabetics or with missed meals.\n\nLactic Acidosis: A rare but life-threatening effect of Metformin—renal function monitoring is essential.\n\nGI Side Effects: Voglibose and Metformin may cause bloating, flatulence, or diarrhea (usually temporary).\n\nVitamin B12 Monitoring: Long-term Metformin use may reduce B12 absorption.\n\nLiver and Kidney Function: Regular monitoring is recommended for safe long-term use.\n\n \n\nAdverse Effects\nCommon:\nGlimepiride: Mild hypoglycemia, dizziness, slight weight gain.\n\nVoglibose: Gas, abdominal discomfort, mild diarrhea.\n\nMetformin SR: Nausea, bloating, metallic taste, loose stools.\n\nRare but Serious:\nLactic acidosis (from Metformin).\n\nSevere hypoglycemia (especially if meals are skipped).\n\nAllergic reactions such as rash, itching, or swelling.\n\nElevated liver enzymes.\n\nSeek medical attention if symptoms such as rapid breathing, confusion, severe fatigue, or muscle pain occur.\n\n \n\nDrug Interactions\nIncreased hypoglycemia risk: With insulin, beta-blockers, and sulfonylureas.\n\nReduced Metformin efficacy: With corticosteroids, estrogens, and diuretics.\n\nLactic acidosis risk: Higher with alcohol or iodinated contrast agents. ",
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"name": "Formoterol Fumarate Dihydrate Ip 6 mcg & Budesonide IP 400 mcg",
"description": "BUDESHINE F 400 CAP - This is a combination inhalation therapy used in the management of asthma and Chronic Obstructive Pulmonary Disease (COPD).\n\n \nMechanism of Action:\n\nFormoterol Fumarate: A long-acting β2-adrenergic agonist (LABA) that relaxes airway smooth muscles, providing rapid and sustained bronchodilation.\n\nBudesonide: An inhaled corticosteroid (ICS) that reduces airway inflammation, swelling, and mucus production.\n\nTogether, they offer dual action—quick relief of bronchospasm and long-term control of airway inflammation.\n\n \n\nIndications:\n\nAsthma (for patients not controlled adequately with inhaled corticosteroids alone).\n\nChronic Obstructive Pulmonary Disease (COPD) with reversible airway obstruction.\n\nPrevention of asthma attacks and reduction of COPD exacerbations.\n\n \n\nKey Benefits:\n\nProvides fast and sustained relief from breathing difficulty.\n\nControls both inflammation and bronchospasm.\n\nReduces the frequency and severity of asthma/COPD flare-ups.\n\nImproves overall lung function and quality of life.\n\n \nDosage and Administration:\n\nAdministered via inhalation as directed by a physician.\n\nDose depends on the severity of disease and patient response.\n\nRegular use is required for effective control—not for acute asthma attacks.\n(Exact dosing schedule to be prescribed by the doctor.)",
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"description": "TELAVINCE 300 is a high-quality antiviral medication containing Tenofovir Disoproxil Fumarate 300 mg, specifically formulated for the effective management of HIV-1 infection and chronic Hepatitis B in adults and adolescents. Manufactured under strict pharmaceutical standards, TELAVINCE 300 offers consistent, potent, and clinically proven antiviral action, helping to suppress viral replication and improve immune function.\n\nTenofovir Disoproxil Fumarate is a nucleotide reverse transcriptase inhibitor (NtRTI). It works by interfering with the enzyme reverse transcriptase, which is essential for viral replication in HIV and Hepatitis B viruses. By inhibiting this enzyme, TELAVINCE 300 reduces the amount of virus in the body, helping to prevent further immune system damage and liver complications.\n\n \nKey Indications:\n \n\nTELAVINCE 300 is indicated for:\n\nHIV-1 Infection: In combination with other antiretroviral agents for the treatment of HIV-1 in adults and adolescents (aged 12 years and older, weighing at least 35 kg).\n\nChronic Hepatitis B: For the treatment of chronic hepatitis B virus infection in adults and adolescents with compensated liver disease and evidence of active viral replication.\n\n \nMechanism of Action:\n \nTenofovir Disoproxil Fumarate is a prodrug of tenofovir, which, once absorbed and metabolized in the body, is converted into tenofovir diphosphate, the active form. Tenofovir diphosphate acts as a competitive inhibitor of reverse transcriptase, incorporating itself into the viral DNA chain and causing premature chain termination. This process disrupts the life cycle of the virus, significantly reducing its ability to multiply and spread.\n\n \nDosage and Administration:\n \n\nRecommended Dose for Adults and Adolescents (≥12 years, ≥35 kg): One tablet (300 mg) once daily, preferably with food.\n\nFor HIV Treatment: Administer in combination with other antiretroviral medications as per the treatment regimen.\n\nFor Chronic Hepatitis B: Monotherapy or as part of combination therapy, depending on patient condition and physician's assessment.\n\nDosage adjustments may be required in patients with renal impairment. Close monitoring is recommended for patients with existing kidney disease.\n\n \nKey Benefits of TELAVINCE 300:\n \n\nPotent Antiviral Action: Rapid and sustained suppression of HIV and HBV replication.\nOnce-Daily Dosing: Improves patient compliance and treatment adherence.\n\nBacked by Clinical Research: Proven efficacy in managing viral load and improving immune markers (CD4 count).\n\nTrusted Quality: Manufactured under GMP-certified facilities with stringent quality control processes.\n\nPart of First-Line Therapy: Recommended in various national and international treatment guidelines for HIV and Hepatitis B.\n\n \nSafety and Precautions:\n \n\nRenal Monitoring: Tenofovir may affect kidney function. Routine renal function tests are recommended before and during treatment.\n\nBone Mineral Density: Long-term use may reduce bone mineral density. Consider monitoring in patients at risk of osteopenia or osteoporosis.\n\nHepatic Flare: Discontinuation of therapy in hepatitis B patients may result in severe acute exacerbations. Liver function should be closely monitored post-treatment.\n\nLactic Acidosis and Hepatomegaly: Rare but serious side effects. Patients presenting symptoms such as abdominal pain, fatigue, or difficulty breathing should seek immediate medical attention.\n\n \n\nPossible Side Effects:\n \n\nMost patients tolerate TELAVINCE 300 well. However, some may experience:\n\nNausea\n\nDiarrhea\n\nHeadache\n\nFatigue\n\nRash\n\nDizziness\n\nDecreased bone mineral density\n\nRenal impairment (in rare cases)\n\nIf any side effects persist or worsen, consult a healthcare professional immediately.\n\n \nStorage Instructions:\n \n\nStore in a cool, dry place below 30°C.\n\nProtect from light and moisture.\n\nKeep out of reach of children.\n\n \n\nWhy Choose TELAVINCE 300?\n \n\nTELAVINCE 300 offers a dependable, clinically validated solution for the long-term management of HIV and Hepatitis B. With its once-daily dosing and proven effectiveness, TELAVINCE 300 is an ideal choice for patients and healthcare providers looking for quality, safety, and therapeutic reliability. It is manufactured by a trusted name in healthcare, ensuring every tablet meets global pharmaceutical standards.\n\n \nDisclaimer:\n \n\nThis product description is for informational purposes only and is not a substitute for professional medical advice. Always consult your doctor or healthcare provider before starting any medication.",
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"name": "CEPHODOXIAA 50 DS",
"description": "CEPHODOXIAA 50 DS is an oral suspension containing Cefpodoxime Proxetil, a third-generation cephalosporin antibiotic. It is widely prescribed for the treatment of bacterial infections in adults and children, including infants and babies.Oral suspension form is particularly useful for children and patients who have difficulty swallowing tablets, ensuring accurate dosing and better compliance.\nComposition\nActive Ingredient: Cefpodoxime Proxetil 50 mg per 5 ml suspension\nBrand Name: CEPHODOXIAA 50 DS\nForm: Oral Suspension\nDrug Class: Cephalosporin Antibiotic\nExcipients: Flavors, sweeteners, stabilizers for palatability and suspension stability\nCefpodoxime Proxetil Oral Suspension IP Uses\nCEPHODOXIAA 50 DS is prescribed for a wide variety of bacterial infections:\nRespiratory Tract Infections\nTonsillitis, Pharyngitis\nBronchitis and Pneumonia\nEar, Nose & Throat (ENT) Infections\nAcute Sinusitis\nOtitis Media (middle ear infection)\nUrinary Tract Infections (UTIs)\nCystitis and kidney infections\nSkin & Soft Tissue Infections\nImpetigo, Cellulitis\nInfected wounds and abscesses\nOther Indications\nGonorrhea (in selected cases)\nPediatric bacterial infections where oral dosing is preferred\nFor babies and children: The oral suspension allows precise weight-based dosing, making it safe and convenient for pediatric infections.\nHow Cefpodoxime Proxetil Oral Suspension Works\nCefpodoxime Proxetil is a beta-lactam antibiotic that:\nInhibits bacterial cell wall synthesis\nWeakens bacterial cells, causing cell death\nEffective against both Gram-positive and Gram-negative bacteria\nThis mechanism helps control infections and prevents their spread.\nDosage & Administration \nInfants & Children: Dose is based on body weight and prescribed by a pediatrician.\nCommonly 5–10 mg/kg/day, divided into 2 doses daily.\nAdults: Typically 100–200 mg every 12 hours, depending on infection severity.\nAdministration Tips:\nShake the bottle well before use.\nUse the measuring cup or spoon provided for accurate dosing.\nCan be taken with or without food, but giving after meals may reduce stomach upset.\nComplete the full course even if symptoms improve.\nBenefits of Cefpodoxime Proxetil Oral Suspension\nEasy to administer for children and babies\nBroad-spectrum coverage for respiratory, urinary, and skin infections\nHelps in rapid infection control\nSafe and effective with minimal side effects when taken as prescribed\nSuspension form allows accurate weight-based dosing\nSide Effects of Cefpodoxime Proxetil Oral Suspension\nMild side effects may include:\nDiarrhea or loose stools\nNausea or vomiting\nStomach pain\nHeadache or dizziness\nSkin rash or itching\nSerious side effects (rare):\nSevere allergic reaction (swelling, rash, difficulty breathing)\nSevere diarrhea indicating Clostridium difficile infection\nLiver enzyme elevation\nSeek medical attention if any severe or persistent side effects occur.\nPrecautions & Warnings\nAvoid if allergic to cephalosporins, penicillin, or other beta-lactam antibiotics\nUse cautiously in patients with kidney or liver disease\nNot effective against viral infections like flu or common cold\nPregnant or breastfeeding women should consult a doctor before use\nAlways complete the full prescribed course to prevent antibiotic resistance\nDrug Interactions\nAntacids containing magnesium or aluminum may reduce absorption\nProton pump inhibitors (PPIs) like omeprazole\nBlood thinners (e.g., warfarin – monitor for increased bleeding risk)\nOther antibiotics may interact and alter effectiveness\nConclusion\nCEPHODOXIAA 50 DS (Cefpodoxime Proxetil Oral Suspension IP) is a safe and effective solution for treating bacterial infections in adults, children, and babies.",
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"description": "Description: \nSACUSMART 200 is a combination medicine containing Sacubitril (97 mg) and Valsartan (103 mg), specifically designed to manage chronic heart failure with reduced ejection fraction (HFrEF). This dual-acting therapy is classified as an angiotensin receptor neprilysin inhibitor (ARNI) and is widely prescribed to reduce the risk of cardiovascular death and hospitalization in patients with heart failure.\n\nHeart failure is a progressive condition where the heart cannot pump blood efficiently to meet the body’s needs. SACUSMART 200 improves the efficiency of the heart by relaxing blood vessels, reducing fluid retention, and lowering strain on the heart, helping patients live a better and longer life.\n\n \nWhat is SACUSMART 200?\n \n\nSACUSMART 200 is a highly effective heart failure medication that combines two active components:\n\nSacubitril (97 mg) – a neprilysin inhibitor that increases levels of natriuretic peptides, leading to vasodilation, sodium excretion, and reduced stress on the heart.\n\nValsartan (103 mg) – an angiotensin II receptor blocker (ARB) that relaxes blood vessels, lowers blood pressure, and prevents harmful effects of angiotensin II.\n\nTogether, these mechanisms make SACUSMART 200 a superior alternative to traditional ACE inhibitors or ARBs alone in treating chronic heart failure.\n\n \nUses of SACUSMART 200\n \n\nSACUSMART 200 is prescribed for:\n\nChronic heart failure with reduced ejection fraction (HFrEF)\n\nReducing risk of hospitalization due to worsening heart failure\n\nImproving survival rates in patients with heart failure\n\nEnhancing exercise tolerance and quality of life in long-term heart failure management\n\n \nBenefits of SACUSMART 200\n \n\nDual action with neprilysin inhibition + ARB effect for comprehensive heart protection\n\nProven to reduce mortality and hospitalization risk in heart failure patients\n\nImproves symptoms such as breathlessness, fatigue, and swelling\n\nHelps patients regain better physical stamina and daily activity levels\n\nLong-term use significantly contributes to improved quality of life\n\n \nPossible Side Effects of SACUSMART 200\n \n\nWhile SACUSMART 200 is effective and generally well tolerated, some patients may experience:\n\nLow blood pressure (hypotension)\n\nIncreased blood potassium levels (hyperkalemia)\n\nDizziness or light-headedness\n\nKidney function changes\n\nCough\n\nRarely, serious allergic reactions or angioedema (swelling of face, lips, or throat)\n\nImmediate medical attention is required if severe swelling, difficulty breathing, or fainting occurs.\n\n \nPrecautions Before Using SACUSMART 200\n \n\nDo not use if you are allergic to sacubitril, valsartan, or other ARBs\n\nAvoid if you have taken an ACE inhibitor within the last 36 hours due to the risk of angioedema\n\nNot recommended for patients with a history of hereditary angioedema\n\nCaution in patients with severe kidney or liver disease\n\nPregnant and breastfeeding women should avoid this medicine due to harmful effects on the baby\n\nAlways monitor blood pressure, kidney function, and potassium levels while on this treatment\n\n \nDrug Interactions\n \n\nSACUSMART 200 may interact with:\n\nACE inhibitors – should not be combined, risk of angioedema\n\nPotassium supplements or potassium-sparing diuretics – risk of high potassium\n\nNSAIDs (e.g., ibuprofen, naproxen) – may reduce kidney function\n\nLithium – risk of lithium toxicity\n\nDiuretics – may increase the risk of low blood pressure\n\nAlways inform your doctor about all medicines, supplements, or herbal products you are taking before starting SACUSMART 200.\n\n \nConclusion\n \n\nSACUSMART 200 (Sacubitril 97 mg & Valsartan 103 mg) is a breakthrough treatment in managing chronic heart failure with reduced ejection fraction (HFrEF). By combining neprilysin inhibition and angiotensin receptor blockade, it not only reduces symptoms but also significantly lowers the risk of hospitalization and death, improving both longevity and quality of life.\n\nFor patients living with heart failure, SACUSMART 200 offers a scientifically proven and clinically superior solution to regain control over their health and live a more fulfilling life.",
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"description": "TRELAQWK 50 is a modern oral antidiabetic tablet containing Trelagliptin 50 mg, specially developed for adults with type 2 diabetes mellitus. This once-weekly medication helps regulate blood sugar effectively, offering both convenience and strong clinical outcomes. With its advanced formulation, TRELAQWK 50 supports better glycemic control, making it easier for patients to lead a balanced and healthier lifestyle.\nManufactured under strict quality standards, TRELAQWK 50 ensures patient compliance, long-term safety, and efficacy in diabetes management.\nKey Ingredient\nTrelagliptin (50 mg):\nA unique, long-acting DPP-4 (dipeptidyl peptidase-4) inhibitor that allows weekly dosing, ensuring higher treatment adherence while maintaining effective control over blood glucose levels.\nKey Benefits of TRELAQWK 50\nProvides consistent blood sugar management with just one tablet per week\nEnhances insulin secretion while lowering glucagon levels in a glucose-dependent manner\nHelps reduce both fasting and postprandial blood glucose\nConvenient choice for patients with busy schedules who struggle with daily tablets\nLow risk of hypoglycemia when used as monotherapy\nSupports long-term improvement in HbA1c levels\nMechanism of Action – How TRELAQWK 50 Works\nTRELAQWK 50 works by blocking the DPP-4 enzyme, which normally degrades incretin hormones such as GLP-1 and GIP. These incretins are vital for maintaining blood sugar balance. By prolonging incretin activity, trelagliptin:\nStimulates insulin secretion from the pancreas\nReduces glucagon release from alpha cells\nHelps lower blood sugar, particularly after meals\nThis mechanism provides both effective glycemic control and improved patient compliance.\nDirections for Use\nTake one tablet of TRELAQWK 50 once a week, on the same day each week\nCan be taken with or without food\nSwallow whole with a glass of water\nFollow your doctor’s advice for dosage adjustment\nDo not double the dose if missed; consult your healthcare provider\nPossible Side Effects\nTRELAQWK 50 is usually well-tolerated. However, some patients may experience:\nMild headache\nNasopharyngitis (cold-like symptoms)\nDiarrhea\nStomach discomfort or indigestion\nRare allergic reactions (rash, itching)\nIf any unusual or persistent side effects occur, seek medical advice promptly.",
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"description": "Fluticasone Nasal Spray IP is a widely prescribed medication for managing nasal allergies, sneezing, runny nose, and nasal congestion. Marketed under the trusted brand name FLUTICATONE PROP NASAL SPRAY, it provides fast and effective relief from seasonal and perennial allergic rhinitis. Patients suffering from chronic nasal blockage, sinus discomfort, or persistent sneezing often find fluticasone nasal spray as one of the most reliable treatments. With its targeted action, it works directly in the nasal passages to reduce inflammation, making breathing easier and improving overall comfort.\n\nWhat is Fluticasone Nasal Spray IP?\n\nFluticasone belongs to the class of corticosteroids, which are powerful anti-inflammatory agents. When delivered as a nasal spray, it works locally in the nose to reduce swelling, mucus production, and irritation caused by allergens such as dust, pollen, or pet dander.\n\nUnlike oral medications, fluticasone nasal spray acts directly at the site of the problem, providing long-lasting relief with fewer systemic side effects. FLUTICATONE PROP NASAL SPRAY is therefore a safe, convenient, and effective option for patients struggling with allergic symptoms.\n\nUses of Fluticasone Nasal Spray\n\nThe uses of fluticasone nasal spray cover a wide range of allergic and nasal conditions, such as:\n\nRelief from seasonal allergies (hay fever).\n\nControl of perennial allergic rhinitis (year-round symptoms).\n\nReduction of nasal congestion and swelling.\n\nManagement of sneezing, itching, and runny nose.\n\nSupporting patients with sinus discomfort due to allergy-related inflammation.\n\nFor many patients, using FLUTICATONE PROP NASAL SPRAY daily provides consistent relief and helps restore normal breathing.\n\nDosage and How to Use\n\nThe usual recommended dose for adults is one to two sprays in each nostril once daily, or as directed by a doctor.\n\nChildren’s dosage should always be determined by a healthcare provider.\n\nShake the spray bottle gently before each use.\n\nClear nasal passages before spraying for best absorption.\n\nUse consistently for maximum benefit, as the full effect may take a few days.\n\nSide Effects of Fluticasone Nasal Spray\n\nMost patients tolerate fluticasone nasal spray well. However, some may experience mild side effects, including:\n\nDryness or irritation in the nose or throat.\n\nNosebleeds.\n\nMild headache.\n\nSneezing immediately after use.\n\nRarely, changes in sense of taste or smell.\n\nSevere side effects are uncommon, but if patients experience persistent nosebleeds, vision changes, or difficulty breathing, they should consult a doctor immediately.\n\nPrecautions Before Using\n\nBefore starting FLUTICATONE PROP NASAL SPRAY, patients should take the following precautions:\n\nInform the doctor if you have recent nasal surgery or injury.\n\nUse with caution if you have asthma, tuberculosis, or immune system problems.\n\nPregnant and breastfeeding women should use only under medical advice.\n\nAvoid exceeding the recommended dose to prevent unwanted side effects.\n\nRegular monitoring may be advised for patients on long-term use.\n\nDrug Interactions\n\nFluticasone nasal spray may interact with other medicines. Patients should inform their doctor if they are taking:\n\nStrong antifungal medicines (like ketoconazole).\n\nCertain HIV medications (ritonavir, cobicistat).\n\nOther steroid medications.\n\nProper medical guidance ensures safe and effective use without harmful interactions.\n\nWhy Choose Steris Healthcare?\n\nWhen it comes to safe and effective medicines, Steris Healthcare is a name patients and doctors trust. By choosing FLUTICATONE PROP NASAL SPRAY, you get:\n\nA high-quality formulation designed for fast allergy relief.\n\nStrict quality control standards to ensure safety and effectiveness.\n\nA product trusted by healthcare professionals across India.\n\nA patient-centric approach where comfort and results are prioritized.\n\nSteris Healthcare continues to provide advanced solutions in healthcare, making treatments more reliable and accessible for patients.",
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"name": "BENZTETRA 25",
"description": "BENZTETRA 25 contains the active ingredient tetrabenazine 25mg, a specialized medication used primarily to manage involuntary movements associated with neurological disorders. Tetrabenazine is classified as a vesicular monoamine transporter 2 (VMAT2) inhibitor and works by regulating the levels of neurotransmitters such as dopamine, serotonin, norepinephrine, and histamine in the brain. This correction of chemical imbalances helps reduce excessive and uncontrolled muscle movements. BENZTETRA 25 is especially valuable for patients suffering from movement disorders that significantly impact their daily functioning. It helps improve motor control, thereby enhancing quality of life for those affected. This medication is prescribed mainly to treat chorea—a movement disorder characterized by jerky, irregular, and uncontrollable muscle movements—that is caused by Huntington disease.\n\nWhat is BENZTETRA 25?\nBENZTETRA 25 is a therapeutic tablet containing tetrabenazine 25mg, designed to treat involuntary movements (chorea) linked to Huntington disease. It does not cure Huntington disease nor address cognitive or psychiatric symptoms of the disease but effectively reduces the severity of abnormal movements by altering neurotransmitter activity in the brain.\n\nUses of BENZTETRA 25\n\nTo treat chorea (a movement disorder) that is caused by Huntington disease.\n\nTo control involuntary muscle movements in Huntington’s disease patients.\n\nManagement of other hyperkinetic movement disorders as determined by a healthcare provider (such as tardive dyskinesia or Tourette syndrome in some cases).\n\nTo reduce excessive motor activity caused by abnormal nerve signaling in the brain, improving voluntary muscle control.\n\nSide Effects of BENZTETRA 25\n\nDrowsiness and fatigue, which may affect alertness.\n\nInsomnia or difficulty sleeping.\n\nNausea, vomiting, or abdominal discomfort.\n\nParkinsonism symptoms such as tremors, muscle rigidity, and slowed movements (bradykinesia).\n\nMood alterations including depression, anxiety, and in severe cases, suicidal thoughts.\n\nRare serious reactions like allergic responses, heart rhythm irregularities, or neuroleptic malignant syndrome (characterized by high fever, muscle stiffness).\n\nPrecautions Before Using BENZTETRA 25\n\nInform your doctor if you have a history of depression, suicidal thoughts, or any psychiatric illness.\n\nAvoid use if you have severe liver disease or have recently taken monoamine oxidase inhibitors (MAOIs).\n\nCaution in patients with cardiac issues due to potential QT interval prolongation.\n\nUse with care when driving or operating machinery as BENZTETRA 25 may cause dizziness or drowsiness.\n\nDo not stop the medication suddenly without consulting your healthcare provider, as symptoms might worsen.\n\nRegular monitoring by a healthcare professional is recommended to assess side effects and efficacy.\n\nDrug Interactions: What Drugs Interact with BENZTETRA 25?\n\nMAO inhibitors such as isocarboxazid, phenelzine, selegiline, and others can cause dangerous interactions and should not be used concurrently.\n\nOther drugs that affect serotonin levels, including selective serotonin reuptake inhibitors (SSRIs), may increase the risk of serotonin syndrome.\n\nCaution with other medications known to prolong the QT interval or those affecting dopamine systems.\n\nInteractions with neuroleptics or antipsychotics require close medical supervision due to additive effects on movement and mood.\n\nConclusion\nBENZTETRA 25, containing tetrabenazine 25mg, is a vital medication for managing chorea associated with Huntington disease by modulating neurotransmitter levels in the brain to reduce involuntary movements. While it offers substantial benefits in improving motor control, careful attention to side effects, precautions, and drug interactions is essential for safe and effective use. Always follow the guidance of a healthcare professional when using BENZTETRA 25 to ensure optimal outcomes and safety.",
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"description": "MAGRAL 160 is a pharmaceutical medication containing megestrol acetate 160 mg, a synthetic progestin known for its potent antineoplastic and appetite-stimulating properties. This drug is primarily prescribed to manage significant health challenges such as unexplained weight loss, anorexia, and cachexia, especially in patients suffering from chronic conditions like cancer or AIDS. Additionally, megestrol acetate functions as a hormone therapy agent employed in the treatment of certain hormone-sensitive malignancies. Its dual action both supports tumor management and improves patients' nutritional status by stimulating appetite and promoting weight gain, thereby enhancing overall quality of life. The drug is regarded as a crucial option in oncology and palliative care for managing complex conditions related to hormone-dependent cancers and severe wasting syndromes.\n\nWhat is MAGRAL 160?\nMAGRAL 160 is an oral medication formulated with megestrol acetate 160 mg, a synthetic progestin hormone derivative. It works primarily by modulating hormone receptors and altering hormone levels that influence the growth of hormone-responsive tumors such as breast and endometrial cancers. Apart from its antineoplastic action, it stimulates appetite by acting on the hypothalamic centers responsible for hunger, helping patients suffering from severe weight loss regain a healthy appetite and weight.\n\nUses of MAGRAL 160\n\nTo treat hormone-dependent cancers, specifically advanced breast cancer and endometrial cancer.\n\nTo stimulate appetite and promote weight gain in patients experiencing anorexia, cachexia, or unexplained severe weight loss related to chronic illnesses like cancer or AIDS.\n\nTo manage wasting syndromes that lead to malnutrition and significant weight loss.\n\nTo serve as an antineoplastic agent in hormone-sensitive malignancies.\n\nIn short, MAGRAL 160 is primarily used to treat anorexia and cachexia or serious unexplained weight loss and is also used as an antineoplastic agent to treat certain types of malignancy.\n\nSide Effects of MAGRAL 160\n\nWeight gain (often desirable but can be excessive)\n\nFluid retention and edema (swelling)\n\nNausea and vomiting\n\nDiarrhea or constipation\n\nVaginal bleeding or spotting in women\n\nFatigue, weakness, and insomnia\n\nHeadache and dizziness\n\nIncreased risk of blood clots (deep vein thrombosis or pulmonary embolism)\n\nHormonal imbalances, such as decreased sex hormone levels, which can lead to sexual dysfunction or bone density loss\n\nAllergic reactions including rash or itching\n\nPatients should report severe or unusual symptoms, especially signs of blood clots such as limb swelling, chest pain, or sudden shortness of breath, immediately to their healthcare provider.\n\nPrecautions before Using MAGRAL 160\n\nInform your doctor if you are pregnant, breastfeeding, or planning to conceive as MAGRAL 160 is contraindicated in pregnancy.\n\nDisclose any history of blood clots, cardiovascular diseases, liver or kidney impairment.\n\nPatients with diabetes should monitor blood sugar closely as megestrol acetate may cause hyperglycemia.\n\nAvoid sudden discontinuation without medical advice to prevent potential hormonal withdrawal effects.\n\nRegular monitoring is required, including hormone levels and blood tests, to assess efficacy and safety during treatment.\n\nUse cautiously in patients at risk for deep vein thrombosis or pulmonary embolism due to increased clotting risks.\n\nDrug Interactions: What Drugs Interact with MAGRAL 160?\n\nCYP3A4 enzyme inducers (e.g., rifampin, phenytoin) may reduce the effectiveness of megestrol acetate by increasing its metabolism.\n\nConcurrent use with blood thinners (anticoagulants) requires careful monitoring as MAGRAL 160 might influence clotting parameters.\n\nCombining with drugs that affect hormonal pathways, such as other hormonal therapies or corticosteroids, may alter treatment outcomes.\n\nInteractions with diabetes medications might necessitate dose adjustment due to potential effects on blood sugar control.\n\nCareful medical supervision is necessary when used with immunosuppressants or other chemotherapy agents to avoid additive side effects or altered drug levels.\n\nConclusion\nMAGRAL 160, containing megestrol acetate 160 mg, is a clinically validated medication widely used to manage complex conditions such as hormone-dependent cancers as well as severe weight loss due to anorexia and cachexia. Its unique ability to act both as an antineoplastic agent and an appetite stimulant makes it invaluable in improving patient outcomes, nutritional status, and overall quality of life. Patients prescribed MAGRAL 160 should adhere strictly to their healthcare provider’s instructions and report any adverse effects promptly. This medication should always be used under medical supervision to ensure optimal benefits and minimize risks.",
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