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{ "products": [ { "_id": "6a7722af7f45a0190eb37920", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Tolperisone Hydrochloride & Paracetamol Tablets", "description": "TOPERITIME P 150/325: Dual-Action Relief for Musculoskeletal Pain and Spasms\nTOPERITIME P 150/325 is a prescription combination therapy formulated to treat acute musculoskeletal discomfort, muscle stiffness, and associated inflammatory pain. By uniting a centrally acting muscle relaxant with a proven analgesic, this film-coated tablet addresses both the neurological and physical aspects of muscle strain, restoring movement and facilitating recovery.\n\nActive Ingredients\nEach film-coated tablet contains:\n\nTolperisone Hydrochloride (150 mg): A muscle relaxant targeting involuntary contractions within the central nervous system.\n\nParacetamol (325 mg): A widely recognized analgesic and antipyretic agent that blocks pain signal transmission.\n\nAvailable in blister packaging and dispensed strictly under a licensed physician's order.\n\nTherapeutic Mechanism\nPainful muscle conditions often create a feedback loop where localized pain triggers involuntary spasms, which in turn exacerbate the pain. TOPERITIME P 150/325 disrupts this cycle through a two-pronged mechanism:\n\nNeuromuscular Regulation: Tolperisone Hydrochloride acts on the spinal cord and brainstem reflexes to inhibit hyperactive nerve impulses driving muscle tension. Unlike traditional skeletal muscle relaxants, it achieves this with minimal central nervous system depression, significantly reducing the likelihood of heavy sedation.\n\nNociceptive Blocking: Paracetamol inhibits prostaglandin synthesis within the central nervous system, raising the body's overall pain threshold and attenuating pain signals originating from injured tissues.\n\nBy simultaneously relaxing tight muscle fibers and dampening pain sensation, the formulation provides comprehensive symptomatic relief.\n\nClinical Indications\nHealthcare professionals may prescribe TOPERITIME P 150/325 for various acute and subacute conditions characterized by pain and hypertonia, including:\n\nAcute muscle spasms and athletic injuries\n\nAcute or chronic lower back pain (lumbago)\n\nCervical spine discomfort and stiff neck\n\nCervical and lumbar spondylosis\n\nFrozen shoulder (adhesive capsulitis)\n\nPost-operative or post-traumatic muscle recovery\n\nGeneralized connective tissue or orthopedic pain\n\nKey Clinical Features\nBalanced Dual Action: Simultaneously targets involuntary contractions and pain sensation.\n\nLow-Sedation Profile: Tolperisone allows patients to maintain daily function without severe daytime drowsiness typical of older relaxants.\n\nEnhanced Mobility: Reduces joint and tissue stiffness, enabling better engagement in physical rehabilitation.\n\nStreamlined Regimen: Combines two therapeutic agents into a single convenient dosage form.\n\nUsage Guidelines\nThis medication must be taken strictly in accordance with a medical prescription.\n\nAdministration: Swallow the tablet whole with water. Do not crush, chew, or split the film-coated tablet.\n\nTiming: Take immediately after a meal to reduce potential gastrointestinal upset, unless directed otherwise by a doctor.\n\nCompliance: Complete the full course prescribed by your physician, and do not alter the recommended dosage.\n\nPotential Side Effects\nWhile generally well-tolerated, some individuals may experience mild side effects, including:\n\nGastrointestinal distress or mild nausea\n\nTransient dizziness or lightheadedness\n\nHeadaches\n\nGeneral fatigue or muscular weakness\n\nRare: Hypersensitivity reactions or cutaneous skin rashes (discontinue use and consult a physician immediately if severe symptoms appear).\n\nSafety Precautions and Considerations\nConsult a medical practitioner prior to initiating treatment if any of the following apply:\n\nPre-existing hepatic (liver) or renal (kidney) impairment\n\nKnown hypersensitivity to Tolperisone, Paracetamol, or related compounds\n\nPregnancy, plans for pregnancy, or active breastfeeding\n\nHistory of chronic alcohol dependency (due to increased liver sensitivity with Paracetamol)\n\nConcurrent use of other medications, particularly other products containing Paracetamol or central nervous system depressants\n\nStorage and Handling\nStore in a cool, dry area below 25°C (77°F).\n\nProtect from direct light, heat, and moisture.\n\nKeep strictly out of reach of children and pets.\n\nCheck the packaging expiration date before administration.\n\nFrequently Asked Questions\nWhat primary conditions does TOPERITIME P 150/325 treat?\n\nIt is indicated for short-term relief from acute musculoskeletal pain, muscle spasms, neck strains, backaches, and related orthopedic disorders.\n\nWhy is Tolperisone combined with Paracetamol?\n\nTolperisone eases muscle tightness at the neurological level, while Paracetamol lowers overall pain perception, creating a synergistic effect that addresses both spasm and pain together.\n\nWill this medication cause severe drowsiness?\n\nTolperisone is specifically designed to exert less sedating activity compared to older muscle relaxants. However, individual sensitivity varies, so caution is advised when driving or operating machinery until individual tolerance is established.\n\nIs TOPERITIME P 150/325 available over the counter?\n\nNo. It requires a valid medical prescription and direct supervision by a registered healthcare professional.", "price": 95.0, "discountamount": 29.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2493, "imageuri": "https://productimages.withfloats.com/actual/6a7722b0ed25653efa18364e.png", "tileimageuri": "https://productimages.withfloats.com/tile/6a7722b0ed25653efa18364e.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-08-08T12:35:59.075Z", "updatedon": "2026-08-08T12:35:59.075Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/tolperisone-hydrochloride-paracetamol-tablets/2493", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "TOPERITIME P 150/325", "category": "ORTHOLOGYRANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6a4cf32ff4503514c0b03999", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "tropicamide eye drops ip", "description": "Tropicamide eye drops IP are a prescription ophthalmic solution used to dilate the pupil (mydriasis) and temporarily paralyze the eye's focusing muscles (cycloplegia) before eye examinations and certain ocular procedures. Dilation typically begins within 20–40 minutes of application and lasts around 4–6 hours, though effects can occasionally persist longer. Tropicamide is widely used by ophthalmologists and optometrists to get a clear, detailed view of the retina, optic nerve, and back of the eye — something that isn't possible through an undilated pupil. It's generally well tolerated, though temporary blurred vision and light sensitivity are expected effects rather than side effects to worry about.\nWhat Is Tropicamide Eye Drops IP?\nTropicamide eye drops IP (manufactured to Indian Pharmacopoeia standards) are an anticholinergic (antimuscarinic) ophthalmic solution, commonly available in 0.5% and 1% strengths. “IP” indicates the formulation meets the quality and purity standards set by the Indian Pharmacopoeia.\nTropicamide belongs to the same broad drug family as atropine but has a much shorter duration of action, which is precisely why it's the preferred choice for routine eye examinations — it does its job quickly and wears off within hours rather than days. It's typically administered directly by a healthcare provider in a clinical or hospital setting, rather than self-administered at home.\nHow Tropicamide Works (Mechanism of Action)\n\nMuscarinic receptor blockade — Tropicamide blocks acetylcholine from binding to muscarinic receptors in the eye's iris sphincter and ciliary muscles.\nPupil dilation (mydriasis) — With the sphincter muscle relaxed, the pupil's natural constricting reflex is blocked, allowing it to widen.\nParalysis of accommodation (cycloplegia) — The ciliary muscle, responsible for adjusting eye focus for near vision, is also relaxed, temporarily reducing the eye's ability to focus on close objects.\nClear visualization of the fundus — With the pupil fully dilated, the examining doctor can clearly view the retina, macula, optic nerve, and vitreous — structures that are otherwise obscured behind an undilated pupil.\nNatural wearing-off — As the drug is metabolized and clears from the eye tissue, muscle tone gradually returns, and the pupil returns to its normal size and reactivity.\n\nClinical Indications\nUse CaseWhy Tropicamide Is UsedDilated fundus examinationAllows a detailed view of the retina, optic nerve, and maculaPre- and post-cataract surgeryAchieves adequate pupil dilation for surgical visibility and reduces post-operative inflammation-related discomfortDiagnosis of refractive errors in childrenCycloplegic effect prevents the eye from actively focusing, giving a more accurate refraction measurementRetinal and posterior segment proceduresSupports clear visualization for laser treatments and retinal surgeryEvaluation of optic nerve or cranial nerve abnormalitiesHelps assess disc swelling, cup-to-disc ratio, and pupillary responsesAnterior uveitis management (adjunctive use)Cycloplegic effect can reduce pain and the risk of complications like posterior synechiae\nDosage Guidelines\nParameterTypical GuidanceStandard strength0.5% or 1% ophthalmic solutionTypical doseOne drop instilled into the eye(s), as directed by the examining doctorOnset of actionDilation usually begins within 20–40 minutesDuration of effectCommonly 4–6 hours; can occasionally last longer depending on individual responseAdministration techniqueTilt the head back, pull down the lower eyelid, instill the drop, then close the eye gently for 2–3 minutes without blinking; applying gentle pressure at the inner corner of the eye can help limit systemic absorptionRepeat dosingA second drop may be used after several minutes if dilation is insufficient, at the doctor's discretion\nTropicamide is typically administered by a healthcare professional in a clinical setting rather than self-instilled at home, and dosing should always follow the specific instructions of the treating doctor.\nKey Benefits\n\nProvides fast, reliable pupil dilation, enabling a thorough examination of the back of the eye\nShort duration of action (compared to atropine) means vision and eye function return to normal within hours, not days\nWell-established, widely used mydriatic with a strong long-term safety record in clinical practice\nSupports more accurate diagnosis of refractive errors in children through its cycloplegic effect\nUseful both for routine diagnostic eye exams and as part of pre-/post-surgical eye care\nAvailable in two strengths (0.5% and 1%), allowing the examining doctor to tailor the degree of dilation needed\n\nPrecautions\n\nShould only be administered by, or under the direct guidance of, a qualified eye care professional\nWear sunglasses after application, since dilated pupils let in significantly more light and cause noticeable light sensitivity\nAvoid driving or operating machinery until vision returns to normal, as focusing on nearby objects (like a dashboard or phone) will be impaired\nDo not wear contact lenses during instillation, as the preservative in some formulations can discolor soft lenses\nUse caution in patients with a history of narrow-angle glaucoma, as pupil dilation can rarely trigger a sudden, serious rise in eye pressure (angle-closure glaucoma)\nIn children, wash hands thoroughly after administration, since rare but serious anticholinergic effects (including psychosis) have been reported, particularly with higher doses or accidental ingestion\nInform the doctor of any history of heart conditions, as anticholinergic effects can occasionally affect heart rate\n\nSide Effects\nCommon side effects (expected and temporary):\n\nBlurred vision, especially for near objects\nIncreased sensitivity to light (photophobia)\nMild stinging or burning sensation on application\nTransient increase in intraocular pressure\n\nLess common side effects:\n\nDry mouth\nHeadache\nIncreased heart rate\nFlushing or mild fever\nEye surface irritation\n\nRare but serious side effects — seek immediate medical attention:\n\nSigns of an allergic reaction: hives, difficulty breathing, swelling of the face, lips, tongue, or throat\nConfusion, slurred speech, agitation, or hallucinations (rare anticholinergic toxicity, more often reported in children)\nSudden eye pain, severe headache, nausea, or vomiting (possible signs of angle-closure glaucoma)\n\nMost side effects resolve on their own as the drug wears off within a few hours; however, any signs of a serious reaction should be reported to a doctor right away.\nComparison with Alternatives\nFeatureTropicamideAtropineOnset of action20–40 minutes30–40 minutesDuration of effect4–6 hours (short-acting)Up to 1–2 weeks (long-acting)Common useRoutine diagnostic dilation, fundus examsCycloplegic refraction in select cases, anterior uveitis managementPreferred settingOutpatient eye exams, same-day proceduresCases needing prolonged cycloplegia\nTropicamide's shorter duration makes it the preferred first choice for most routine eye examinations, where rapid return to normal vision is desirable.\nKey Statistics\n[Placeholder — pending clinical/regulatory team verification. Do not publish without confirmed source citation for dilation success rates, comparative onset/duration data, or incidence rates of rare adverse effects.]\nExpert Insight\n[Placeholder — reserved for a quote from a qualified ophthalmologist or clinical reviewer. Do not publish without a verified, attributable expert quote.]\nFrequently Asked Questions\n1. What is tropicamide eye drops used for?\nTropicamide eye drops are used to dilate the pupil and temporarily relax the eye's focusing muscles, allowing an eye doctor to clearly examine the retina, optic nerve, and back of the eye during routine eye exams and certain procedures.\n2. How long does dilation last with tropicamide?\nDilation typically begins within 20–40 minutes and lasts about 4–6 hours, though this can vary slightly from person to person. Vision usually returns to normal well within the same day.\n3. What are the risks of tropicamide eye drops?\nCommon effects include temporary blurred vision and light sensitivity. Less commonly, dry mouth, headache, or a faster heartbeat can occur. Rare but serious risks include an allergic reaction or, in susceptible individuals, a sudden rise in eye pressure (angle-closure glaucoma) — these require immediate medical attention.\n4. What are the benefits of tropicamide?\nTropicamide allows for fast, reliable pupil dilation with a much shorter recovery time than older agents like atropine, enabling accurate diagnosis of retinal and optic nerve conditions while letting patients return to normal vision within hours.\nConclusion\nTropicamide eye drops IP remain one of the most widely used and trusted tools in modern eye care, offering fast-acting, short-duration pupil dilation that allows eye care professionals to thoroughly examine the structures at the back of the eye. Its short window of action compared to older cycloplegic agents like atropine makes it especially well suited for routine diagnostic exams, where patients need their vision to return to normal within the same day. While temporary blurred vision and light sensitivity are expected parts of the experience, tropicamide has a strong long-term safety record when administered appropriately by a qualified eye care professional. As with any prescription ophthalmic agent, it should only be used under medical supervision, with simple precautions like wearing sunglasses afterward and avoiding driving until vision normalizes.\n\nDisclaimer: This content is for informational purposes only and is not a substitute for professional medical advice. Tropicamide eye drops IP are a prescription medicine and should only be administered by, or under the direct guidance of, a qualified eye care professional.\nManufactured by:\nSteris Healthcare Pvt. Ltd.\nWHO-GMP & ISO Certified Pharmaceutical Manufacturer\nEmail: contact@sterispharma.com | info@sterispharma.com\nContent last reviewed: July 2026", "price": 50.0, "discountamount": 15.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2466, "imageuri": "https://productimages.withfloats.com/actual/6a4cf331dd4ec8cc0aa1b9e4.png", "tileimageuri": "https://productimages.withfloats.com/tile/6a4cf331dd4ec8cc0aa1b9e4.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-07-07T12:38:07.8Z", "updatedon": "2026-07-07T12:38:07.8Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//tropicamide-eye-drops-ip/2466", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CIPVISION TRACOPA 1%", "category": "Opthalmology Range", "tags": [ "tropicamide eye drops ip", "tropicamide eye drops ip uses in hindi", "tropicamide eye drops", "tropicamide eye drops uses", "tropicamide eye drops uses in hindi", "tropicamide eye drops price", "tropicamide eye drops bottle", "tropicamide eye drops side effects", "tropicamide eye drops brand name" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6a43bee2d208c802be053f9d", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Sitagliptin 100mg Metformin Hydrochloride 1000mg Sustained Release Pioglitazone 15 mg", "description": "Managing type 2 diabetes often requires more than a single medication to achieve long-term blood sugar control. Sitagliptin 100mg Metformin Hydrochloride 1000mg Sustained Release Pioglitazone 15 mg is a triple-combination prescription medicine formulated to help adults with type 2 diabetes maintain healthy glucose levels when diet, exercise, and single-drug therapy are not enough.\n\nThis advanced combination works through three different mechanisms to improve insulin sensitivity, reduce glucose production by the liver, and enhance the body's natural insulin response after meals. Because of its multi-action approach, it is frequently prescribed by healthcare professionals for patients requiring comprehensive glycemic control.\n\nIf you are searching for Sitagliptin 100mg Metformin Hydrochloride 1000mg Sustained Release Pioglitazone 15 mg, this guide covers everything you need to know—including how it works, benefits, dosage information, side effects, precautions, storage, and frequently asked questions.\n\nWhat is Sitagliptin 100mg Metformin Hydrochloride 1000mg Sustained Release Pioglitazone 15 mg?\n\nSitagliptin 100mg Metformin Hydrochloride 1000mg Sustained Release Pioglitazone 15 mg is a prescription oral anti-diabetic medicine used to manage Type 2 Diabetes Mellitus. It combines three clinically proven medicines into one convenient tablet to provide better blood sugar management throughout the day.\n\nThe formulation contains:\n\nSitagliptin 100 mg – A DPP-4 inhibitor that increases incretin hormones to improve insulin secretion.\nMetformin Hydrochloride 1000 mg Sustained Release – A biguanide that lowers glucose production by the liver and improves insulin sensitivity.\nPioglitazone 15 mg – A thiazolidinedione that enhances the body's response to insulin.\n\nTogether, these ingredients target multiple causes of high blood sugar, helping patients achieve better diabetes control while reducing the need for multiple separate medications.\n\nHow Does Sitagliptin 100mg Metformin Hydrochloride 1000mg Sustained Release Pioglitazone 15 mg Work?\n\nThis triple-combination tablet works through complementary mechanisms:\n\n1. Sitagliptin\n\nSitagliptin inhibits the DPP-4 enzyme, allowing incretin hormones to remain active longer. These hormones increase insulin release after meals and reduce excess glucagon production.\n\n2. Metformin SR\n\nMetformin Sustained Release decreases glucose production in the liver, reduces intestinal glucose absorption, and improves insulin sensitivity without causing excessive insulin release.\n\n3. Pioglitazone\n\nPioglitazone improves insulin sensitivity in muscle and fat tissues, enabling cells to utilize glucose more effectively.\n\nThe combination helps maintain consistent blood sugar levels throughout the day while lowering both fasting and post-meal glucose.\n\nWhy is This Triple Combination Important?\n\nType 2 diabetes progresses over time, making it difficult for many patients to control blood sugar using a single medication. A triple therapy offers several advantages:\n\nBetter HbA1c reduction\nMultiple mechanisms of action\nReduced insulin resistance\nImproved post-meal glucose control\nLower fasting blood sugar\nSimplified treatment with one tablet\nImproved medication adherence\nReduced need for additional medications\n\nHealthcare providers often prescribe this combination when dual therapy no longer provides adequate glucose control.\n\nKey Benefits of Sitagliptin 100mg Metformin Hydrochloride 1000mg Sustained Release Pioglitazone 15 mg\nExcellent Blood Sugar Control\n\nThe medicine helps reduce both fasting and postprandial blood glucose levels effectively.\n\nTriple Mechanism of Action\n\nEach ingredient targets a different pathway involved in diabetes, resulting in more comprehensive glycemic control.\n\nImproved Insulin Sensitivity\n\nPioglitazone increases insulin responsiveness, helping the body utilize glucose more efficiently.\n\nReduced Liver Glucose Production\n\nMetformin decreases glucose release from the liver, preventing unnecessary increases in blood sugar.\n\nSupports Long-Term Diabetes Management\n\nRegular use, alongside lifestyle modifications, contributes to improved HbA1c levels and reduced diabetes-related complications.\n\nConvenient Once-Daily Regimen\n\nCombining three medicines into a single tablet improves treatment convenience and supports better compliance.\n\nWho May Benefit from This Medicine?\n\nHealthcare professionals may prescribe this medication for adults with Type 2 Diabetes who:\n\nHave uncontrolled blood sugar despite dual therapy\nRequire triple oral anti-diabetic therapy\nHave elevated HbA1c levels\nNeed improved insulin sensitivity\nPrefer fewer tablets in their treatment plan\nAre following dietary and exercise recommendations but require additional glucose control\n\nThis medicine is not intended for Type 1 Diabetes or diabetic ketoacidosis.\n\nHow to Take Sitagliptin 100mg Metformin Hydrochloride 1000mg Sustained Release Pioglitazone 15 mg\n\nAlways follow your physician's instructions.\n\nGeneral recommendations include:\n\nTake once daily or as prescribed.\nSwallow the tablet whole.\nDo not crush, split, or chew the sustained-release tablet.\nTake with food to reduce stomach discomfort.\nTake it at the same time each day.\nContinue exercising and following a diabetic meal plan.\n\nNever stop treatment without consulting your healthcare provider.\n\nPossible Side Effects\n\nLike all prescription medicines, this combination may cause side effects, although not everyone experiences them.\n\nCommon side effects include:\n\nNausea\nStomach discomfort\nDiarrhea\nHeadache\nUpper respiratory infection\nWeight gain\nSwelling of feet or ankles\nMuscle aches\nDizziness\n\nSeek immediate medical attention if you experience:\n\nSevere allergic reaction\nPersistent vomiting\nDifficulty breathing\nSevere abdominal pain\nUnusual fatigue\nYellowing of skin or eyes\nSymptoms of lactic acidosis\nSigns of heart failure, such as rapid weight gain or shortness of breath\nPrecautions Before Using This Medicine\n\nInform your healthcare provider if you have:\n\nKidney disease\nLiver disease\nHeart failure\nBladder cancer history\nPancreatitis\nSevere dehydration\nAlcohol dependence\nVitamin B12 deficiency\nPlanned surgery or imaging with contrast dye\n\nWomen who are pregnant or breastfeeding should use this medicine only under medical supervision.\n\nDrug Interactions\n\nTell your doctor about all medicines you take, including:\n\nInsulin\nSulfonylureas\nDiuretics\nCorticosteroids\nThyroid medicines\nBlood pressure medicines\nRifampicin\nAlcohol\nCimetidine\nCertain antifungal medicines\n\nProper medication review helps minimize interaction risks.\n\nLifestyle Tips for Better Diabetes Control\n\nMedicine works best when combined with healthy lifestyle habits.\n\nRecommended practices include:\n\nFollow a balanced diabetic diet.\nExercise for at least 30 minutes most days.\nMonitor blood sugar regularly.\nMaintain a healthy body weight.\nStay hydrated.\nAvoid smoking.\nLimit alcohol intake.\nGet regular HbA1c tests.\nManage stress effectively.\nAttend routine medical check-ups.\nStorage Instructions\n\nStore the tablets:\n\nBelow 25°C\nIn a cool, dry place\nAway from moisture and direct sunlight\nIn the original packaging\nOut of reach of children and pets\n\nDo not use expired medicine.\n\nWhy Healthcare Professionals Choose This Triple Combination\n\nDoctors frequently recommend Sitagliptin 100mg Metformin Hydrochloride 1000mg Sustained Release Pioglitazone 15 mg because it addresses multiple aspects of diabetes management in a single formulation. By improving insulin secretion, reducing hepatic glucose production, and enhancing insulin sensitivity, it provides comprehensive glycemic control while simplifying treatment. When combined with a healthy lifestyle and regular medical follow-up, it can support long-term diabetes management and help reduce the risk of complications associated with uncontrolled blood sugar.\n\nConclusion\n\nSitagliptin 100mg Metformin Hydrochloride 1000mg Sustained Release Pioglitazone 15 mg is an effective prescription medication designed for adults with Type 2 Diabetes Mellitus who require stronger blood sugar management than single or dual therapy can provide. Its triple-action formula offers improved glycemic control, better insulin utilization, and convenient once-daily dosing. While highly effective, it should always be used under the guidance of a qualified healthcare professional, together with a balanced diet, regular physical activity, and routine blood sugar monitoring for the best long-term outcomes.\n\nHigh-Ranking FAQs (Google Search & Voice Search Optimized)\n1. What is Sitagliptin 100mg Metformin Hydrochloride 1000mg Sustained Release Pioglitazone 15 mg used for?\n\nIt is prescribed to help adults with Type 2 Diabetes Mellitus control blood sugar when lifestyle changes and other oral medicines do not provide adequate glycemic control.\n\n2. How does this triple-combination tablet work?\n\nIt combines three medicines that increase insulin release after meals, reduce glucose production by the liver, and improve the body's sensitivity to insulin, resulting in better overall blood sugar control.\n\n3. Can this medicine be taken once daily?\n\nYes. Many patients take it once daily, but the exact dosage and timing should always follow the prescribing doctor's instructions.\n\n4. Should I take this tablet with food?\n\nYes. Taking it with meals helps reduce stomach-related side effects associated with metformin and improves tolerability.\n\n5. Can this medicine cure diabetes?\n\nNo. It helps control blood sugar levels but does not cure Type 2 Diabetes. Long-term treatment, healthy eating, exercise, and regular monitoring remain essential.\n\n6. What should I do if I miss a dose?\n\nTake the missed dose as soon as you remember unless it is nearly time for your next scheduled dose. Do not take two doses together to make up for a missed dose.\n\n7. Can this medicine cause low blood sugar?\n\nOn its own, the risk is relatively low. However, the likelihood increases when it is used with insulin or sulfonylurea medicines, or if meals are skipped.\n\n8. Is this medicine safe for patients with kidney disease?\n\nPatients with kidney impairment require medical evaluation before using this medicine, particularly because metformin may not be suitable in severe kidney dysfunction.\n\n9. Can I drink alcohol while taking this medication?\n\nAlcohol intake should be limited or avoided, as excessive consumption may increase the risk of serious side effects, including lactic acidosis.\n\n10. Who should not use Sitagliptin 100mg Metformin Hydrochloride 1000mg Sustained Release Pioglitazone 15 mg?\n\nIt should not be used without medical advice by individuals with Type 1 Diabetes, diabetic ketoacidosis, severe kidney disease, certain liver conditions, or a history of serious hypersensitivity to any of its ingredients. Always consult your healthcare provider before starting treatment.", "price": 243.0, "discountamount": 73.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2462, "imageuri": "https://productimages.withfloats.com/actual/6a43bee3de301bd6de277db2.png", "tileimageuri": "https://productimages.withfloats.com/tile/6a43bee3de301bd6de277db2.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-06-30T13:04:34Z", "updatedon": "2026-06-30T13:04:34Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//sitagliptin-100mg-metformin-hydrochloride-1000mg-sustained-release-pioglitazone-15-mg/2462", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "ST GLIPTIN 3D 1000", "category": "DIABETIC RANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6989a63c42154005d2069493", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Citicoline and Piracetam Tablets", "description": "CITICOTIME PM 400 represents a scientifically formulated pharmaceutical combination that brings together two powerful nootropic compounds: Citicoline and Piracetam. This synergistic blend is specifically designed to support cognitive function, enhance mental clarity, and promote overall brain health. Each tablet delivers a precisely calibrated dose of these neurologically active ingredients, making it a preferred choice for individuals seeking to optimize their mental performance, support recovery from neurological conditions, or maintain cognitive vitality as they age.\nThe formulation combines the neuroprotective properties of Citicoline with the cognitive-enhancing effects of Piracetam, creating a comprehensive approach to brain health that addresses multiple pathways of neurological function. This dual-action mechanism makes CITICOTIME PM 400 particularly effective for managing various cognitive challenges and supporting brain function across different age groups and health conditions.\nUnderstanding the Active Ingredients\nCiticoline, also known as CDP-Choline (Cytidine 5'-diphosphocholine), is a naturally occurring compound that plays a crucial role in the synthesis of phosphatidylcholine, a major component of brain cell membranes. This remarkable substance serves as both a choline donor and a source of cytidine, providing the building blocks necessary for maintaining healthy neuronal structures and facilitating efficient neurotransmission.\nPiracetam belongs to the racetam family of nootropics and was one of the first cognitive enhancers ever developed. It works primarily by modulating neurotransmitter systems and enhancing neuroplasticity, the brain's ability to form new connections and adapt to changing demands. Together with Citicoline, it creates a powerful combination that addresses cognitive function from multiple angles.\nPrimary Uses and Indications\nCITICOTIME PM 400 is prescribed for a wide range of neurological and cognitive conditions. It serves as an effective therapeutic intervention for individuals experiencing age-related cognitive decline, helping to slow the progression of memory loss and maintain mental sharpness in older adults. The formulation is particularly valuable for patients recovering from stroke, as it supports neurological rehabilitation and may help restore lost cognitive functions.\nThe medication is also utilized in managing various forms of dementia, including vascular dementia and early-stage Alzheimer's disease, where it helps preserve cognitive abilities and may slow disease progression. Students, professionals, and individuals facing high cognitive demands often use this supplement to enhance focus, concentration, and mental stamina during periods of intensive intellectual work.\nAdditionally, CITICOTIME PM 400 finds application in treating traumatic brain injuries, supporting the recovery process by promoting neuronal repair and protecting against further damage. It's also prescribed for individuals with attention disorders, learning difficulties, and other cognitive impairments that affect daily functioning and quality of life.\nKey Benefits and Therapeutic Advantages\nThe benefits of CITICOTIME PM 400 extend across multiple dimensions of cognitive and neurological health. One of the most significant advantages is enhanced memory formation and recall. The combination of Citicoline and Piracetam supports the mechanisms underlying both short-term and long-term memory, making it easier to learn new information and retrieve stored memories when needed.\nImproved focus and concentration represent another cornerstone benefit. Users often report experiencing sustained attention spans, reduced mental fatigue, and an enhanced ability to engage in complex tasks requiring prolonged cognitive effort. This makes the supplement particularly valuable for individuals whose work or studies demand high levels of mental performance.\nThe formulation provides robust neuroprotective effects, shielding brain cells from oxidative stress, inflammation, and age-related deterioration. This protective action helps maintain the structural integrity of neurons and supports long-term brain health, potentially reducing the risk of neurodegenerative conditions.\nEnhanced cerebral blood flow is another critical benefit. Both active ingredients work to improve circulation within the brain, ensuring that neurons receive adequate oxygen and nutrients while facilitating the removal of metabolic waste products. This improved circulation contributes to better overall brain function and mental clarity.\nUsers frequently experience increased mental energy and reduced brain fog. The supplement helps combat the mental sluggishness that can accompany aging, stress, or illness, promoting a state of alert wakefulness and mental clarity throughout the day.\nThe formulation also supports neuroplasticity and cognitive flexibility, enabling the brain to adapt more readily to new challenges, learn new skills more efficiently, and recover more effectively from neurological insults.\nPotential Side Effects and Considerations\nWhile CITICOTIME PM 400 is generally well-tolerated by most users, it's important to be aware of potential side effects. Common mild effects may include headaches, particularly during the initial days of treatment as the body adjusts to the medication. Some individuals may experience digestive disturbances such as nausea, stomach upset, or mild gastrointestinal discomfort.\nSleep disturbances, including insomnia or vivid dreams, can occur in some users, particularly if the medication is taken too late in the day. To minimize this risk, it's typically recommended to take CITICOTIME PM 400 in the morning or early afternoon.\nOther potential side effects include nervousness, restlessness, or mild anxiety in sensitive individuals. Some users may experience dizziness, particularly when standing up quickly. Rarely, individuals may report skin rashes or allergic reactions, which should prompt immediate medical consultation.\nIt's crucial to inform your healthcare provider about all medications, supplements, and health conditions before starting CITICOTIME PM 400, as interactions may occur with certain drugs, particularly blood thinners and other neurological medications.\nDosage and Administration Guidelines\nThe typical dosage and administration schedule should always be determined by a qualified healthcare professional based on individual needs, health status, and treatment objectives. Generally, the medication is taken orally with water, preferably with meals to enhance absorption and minimize gastrointestinal side effects.\nConsistency in timing is important for maintaining stable blood levels of the active ingredients. Most prescribers recommend taking the supplement in the morning or early afternoon to avoid potential sleep interference. It's advisable to avoid taking CITICOTIME PM 400 on an empty stomach, as this may increase the likelihood of digestive discomfort.\nConclusion\nCITICOTIME PM 400 stands as a scientifically-backed, comprehensive cognitive enhancement solution that addresses brain health through multiple complementary mechanisms. The intelligent combination of Citicoline and Piracetam offers users a powerful tool for maintaining cognitive vitality, supporting recovery from neurological challenges, and optimizing mental performance across various life stages.", "price": 780.0, "discountamount": 234.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2296, "imageuri": "https://productimages.withfloats.com/actual/6989a63f3821a38d68f07a39.png", "tileimageuri": "https://productimages.withfloats.com/tile/6989a63f3821a38d68f07a39.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-02-09T09:17:48.921Z", "updatedon": "2026-05-23T07:23:00.607Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//citicoline-and-piracetam-tablets/2296", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CITICOTIME PM 400", "category": "NEUROLOGY RANGE", "tags": [ "citicoline and piracetam tablets uses", "citicoline and piracetam combination tablets", "citicoline piracetam tablets for brain health", "how citicoline and piracetam tablets work", "citicoline piracetam tablets benefits", "citicoline piracetam tablets side effects", "citicoline piracetam oral tablets", "citicoline piracetam tablet composition", "citicoline piracetam tablets for memory improvement", "citicoline piracetam tablets for cognitive impairment", "what are citicoline and piracetam tablets", "who should take citicoline piracetam tablets", "how long does citicoline piracetam take to work", "citicoline with piracetam tablets", "piracetam citicoline brain supplement tablets", "citicoline piracetam nootropic combination", "citicoline and piracetam tablets price", "citicoline and piracetam tablets uses in hindi", "citicoline and piracetam tablets uses in tamil", "citicoline and piracetam tablets brands", "citicoline and piracetam tablets side effects", "use of citicoline and piracetam tablets", "citicoline and piracetam tablets dosage", "citicoline and piracetam tablets uses in telugu", "citicoline and piracetam tablets uses in english", "citicoline and piracetam tablets use" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69327c28991683751071b8b8", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Polmacoxib 2mg , Paracetamol 325mg", "description": "PUMACOXIB PCM, featuring Polmacoxib 2mg and Paracetamol 325mg, delivers targeted relief from pain, inflammation, and fever associated with conditions like osteoarthritis and rheumatoid arthritis. This combination tablet works synergistically, with Polmacoxib inhibiting the COX-2 enzyme to curb inflammatory prostaglandins, while Paracetamol blocks pain signals in the brain. Patients often experience faster mobility and daily comfort from this dual-action formula.​\n\nProduct Overview and Composition\nPUMACOXIB PCM stands out as a modern pharmaceutical solution crafted for effective management of acute and chronic pain issues. Each tablet contains precisely 2mg of Polmacoxib, a selective COX-2 inhibitor that precisely targets inflammation without broadly affecting other body processes, and 325mg of Paracetamol, a trusted analgesic and antipyretic. This balanced formulation ensures comprehensive coverage against discomfort from joint disorders, muscle strains, or post-injury swelling.​\n\nThe medication's design emphasizes safety and efficacy, making it suitable for ortho patients and those with inflammatory conditions. Produced under high-quality standards, PUMACOXIB PCM offers a convenient single-dose approach to symptom control. Regular use as prescribed supports sustained joint health and reduces reliance on multiple drugs.​\n\nKey Uses of PUMACOXIB PCM\nPUMACOXIB PCM proves highly effective for osteoarthritis, particularly in hip and knee joints, where it alleviates pain, stiffness, and swelling. Rheumatoid arthritis patients benefit from its ability to ease flare-ups, improving grip strength and movement. It also addresses general body aches, back pain, and muscle soreness from injuries or overuse.​\n\nBeyond arthritis, the tablet manages post-surgical discomfort and inflammatory responses in conditions like tendonitis. For fever accompanying pain, such as in flu-related joint issues, Paracetamol component provides prompt temperature reduction. Healthcare providers often recommend it for short-term acute pain or longer-term chronic management under supervision.​\n\nMajor Benefits and Advantages\nOne primary benefit of PUMACOXIB PCM lies in its rapid onset, delivering long-lasting pain relief that enhances daily activities without constant redosing. The selective COX-2 action of Polmacoxib minimizes gastrointestinal risks compared to traditional NSAIDs, allowing safer use for stomach-sensitive individuals. Combined with Paracetamol, it offers fever control alongside anti-inflammatory effects, creating a versatile tool for multifaceted symptoms.​\n\nUsers report improved mobility and quality of life, with reduced joint stiffness enabling better exercise adherence and work productivity. Its lower side effect profile supports extended use in chronic cases, outperforming single-agent therapies in noninferiority studies against alternatives like etoricoxib combinations. Overall, PUMACOXIB PCM promotes holistic pain management with fewer disruptions to routine.​\n\nFast-acting dual relief for pain and swelling.​\n\nEnhanced joint flexibility for arthritis sufferers.​\n\nSafer stomach profile for prolonged therapy.​\n\nConvenient all-in-one tablet for busy lifestyles.​\n\nPotential Side Effects and Precautions\nWhile generally well-tolerated, PUMACOXIB PCM may cause mild effects like nausea, headache, or dizziness in some users, often resolving without intervention. Rare risks include allergic reactions such as rash or swelling, requiring immediate medical attention. Liver concerns arise with Paracetamol overuse, so adherence to dosage—one to two tablets daily—remains crucial.​\n\nAvoid alcohol to prevent liver strain, and consult doctors for kidney, liver, or heart conditions before starting. Pregnant or breastfeeding individuals should seek guidance, as should those on blood thinners or other medications. Monitoring ensures optimal safety, with most experiencing minimal issues at recommended levels.​\n\nCommon Side Effects\tLess Common Risks\tManagement Tips\nNausea, dizziness ​\tAllergic rash, swelling ​\tTake with food; hydrate well\nHeadache ​\tLiver strain (overdose) ​\tFollow dosage; avoid alcohol\nStomach discomfort ​\tHeart-related (rare) ​\tConsult for pre-existing issues\nDosage Guidelines and Best Practices\nSwallow PUMACOXIB PCM whole with water, once or twice daily, adjusting per physician advice based on pain severity. It works with or without meals, though food may ease minor stomach upset. For acute pain, short courses suffice; chronic use needs regular check-ups.​\n\nDo not exceed prescribed amounts to safeguard against Paracetamol accumulation. Store in a cool, dry place away from children. Integrating lifestyle changes like light exercise amplifies results.​\n\nConclusion\nPUMACOXIB PCM with Polmacoxib 2mg and Paracetamol 325mg transforms pain management by blending potent anti-inflammatory and analgesic actions into one reliable tablet. Its benefits in reducing inflammation, easing pain, and boosting mobility make it ideal for arthritis and related woes, all while prioritizing a favorable safety profile. Choose PUMACOXIB PCM for empowered, discomfort-free living—consult your healthcare provider today to integrate it into your wellness plan.​", "price": 295.0, "discountamount": 89.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2232, "imageuri": "https://productimages.withfloats.com/actual/69327c296111c1dae707ef57.png", "tileimageuri": "https://productimages.withfloats.com/tile/69327c296111c1dae707ef57.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-05T06:31:04.077Z", "updatedon": "2026-03-14T06:38:22.671Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//polmacoxib-2mg-paracetamol-325mg/2232", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "PUMACOXIB PCM", "category": "ORTHOLOGYRANG", "tags": [ "Polmacoxib 2mg and Paracetamol 325mg", "Paracetamol blocks pain signals in the brain", "PUMACOXIB PCM,", "Polmacoxib 2mg and Paracetamol 325mg transforms pain" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "692ebab58b1b9a33636fefc6", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Polmacoxib 2mg", "description": "Polmacoxib 2 mg capsules represent a targeted selective COX-2 inhibitor designed specifically for managing pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, and chronic joint issues. Each capsule delivers 2 mg of Polmacoxib, offering once-daily dosing for convenient, long-term use with a reduced risk of gastrointestinal complications compared to traditional NSAIDs. This formulation supports joint health by inhibiting the COX-2 enzyme responsible for producing prostaglandins that trigger pain, swelling, and stiffness.​\nTherapeutic Uses of Polmacoxib 2mg\nPolmacoxib 2 mg excels in treating osteoarthritis of the hip and knee, where cartilage breakdown leads to joint pain and reduced mobility. Healthcare providers prescribe it to alleviate symptoms of rheumatoid arthritis, ankylosing spondylitis, acute injuries like sprains, postoperative swelling, and chronic inflammatory disorders. By focusing on inflammation at its source, it helps patients regain daily functionality, from walking without stiffness to performing routine tasks with less discomfort.​\nThe medication proves particularly valuable for active individuals or those in later years seeking mobility support. It addresses post-surgery inflammation and muscle strains by quickly reducing localized swelling and pain, promoting faster recovery. Standard administration involves one 2mg capsule daily, with or without food, as directed by a physician to optimize absorption and efficacy.​\nKey Benefits and Advantages\nPolmacoxib 2mg stands out for its selective COX-2 inhibition, sparing the COX-1 enzyme that protects the stomach lining, thus minimizing risks like ulcers and bleeding common in non-selective NSAIDs. Patients experience rapid pain relief alongside improved joint flexibility, enabling better movement and reduced stiffness for enhanced quality of life.​\n\nEffective inflammation control targets swelling in osteoarthritis and rheumatoid arthritis, preserving cartilage and supporting long-term joint function.​\n\nLower gastrointestinal risks make it suitable for extended use, ideal for chronic conditions without frequent stomach upset.​\n\nConvenient once-daily dosing boosts adherence, while potential cardiovascular safety offers reassurance for those with heart concerns when used appropriately.​\n\nPromotes mobility in aging populations, reducing wear on joints and aiding independence during daily activities.​\n\nCompared to older NSAIDs, Polmacoxib provides comparable efficacy with a safer profile for prolonged therapy.​\n\nPotential Side Effects and Precautions\nWhile generally well-tolerated, Polmacoxib 2 mg may cause common mild effects such as nausea, headache, dizziness, or stomach discomfort, which often resolve with continued use. Metabolic changes like elevated blood pressure can occur, especially in hypertensive patients, alongside rare renal issues or allergic reactions.​\n\nSerious risks, though less frequent, include cardiovascular events like heart attack or stroke with long-term high-dose use, particularly in those with pre-existing heart disease, and potential kidney impairment. Contraindications cover third-trimester pregnancy, severe heart or kidney conditions, and allergies to NSAIDs; interactions with blood thinners, diuretics, or ACE inhibitors require monitoring. Always consult a doctor before starting, especially if combining with other medications.​\n\nAspect\tCommon Side Effects\tSerious Risks\tPrecautions\nGastrointestinal\tNausea, upset stomach\tUlcers (reduced risk)\tTake with food if needed ​\nCardiovascular\tBlood pressure rise\tHeart attack, stroke\tMonitor in heart patients ​\nRenal\tMild changes\tKidney failure (rare)\tHydrate well ​\nGeneral\tHeadache, dizziness\tAllergic reactions\tAvoid alcohol ​\nDosage Guidelines and Best Practices\nAdults typically take one 2 mg capsule once daily for osteoarthritis or related pains, adjusting based on response and tolerance under medical supervision. Swallow whole without crushing; maintain consistent timing for steady relief. For acute pain, relief starts within hours, while chronic benefits build over days.​\n\nDo not exceed the prescribed dose to avoid amplified risks. Regular checkups ensure safety, particularly for long-term users. Store in a cool, dry place away from children.​\n\nConclusion: Empower Your Joint Health with Polmacoxib 2 mg\nPolmacoxib 2 mg capsules deliver precise, effective relief for osteoarthritis, rheumatoid arthritis, and inflammatory pains, balancing potent COX-2 inhibition with a favorable safety profile for sustained use. By easing pain, curbing inflammation, and enhancing mobility, it empowers patients to reclaim active lifestyles with fewer compromises. Consult healthcare professionals for personalized advice to maximize benefits while managing risks effectively.", "price": 180.0, "discountamount": 54.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2225, "imageuri": "https://productimages.withfloats.com/actual/692ebabc525aa88c1a67d995.png", "tileimageuri": "https://productimages.withfloats.com/tile/692ebabc525aa88c1a67d995.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-02T10:08:53.463Z", "updatedon": "2026-02-26T06:53:08.037Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//polmacoxib-2mg/2225", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "PUMACOXIB 2 MG", "category": "ORTHOPEDICS RANGE", "tags": [ "Polmacoxib 2mg", "chronic joint issues", "COX-2 enzymes", "osteoarthritis of the hip and knee", "Joint Health with Polmacoxib 2 mg", "pain curbing inflammation.", "prolonged therapy" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69142bf71d499513a92e5772", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Nicorandil Tablets 5mg", "description": "Nicorandil Tablets 5 mg is a vasodilatory anti-anginal medication widely prescribed for the management and prevention of angina pectoris (chest pain) associated with coronary artery disease (CAD). Angina results from an imbalance between the heart’s oxygen demand and supply due to restricted blood flow in the coronary arteries. Nicorandil offers a dual mechanism of action — acting both as a nitrate-like vasodilator and a potassium channel opener, making it unique among anti-anginal agents.\n\nBy improving oxygen delivery to the myocardium and reducing cardiac workload, Nicorandil 5 mg Tablets provide effective relief from anginal pain and reduce the frequency and severity of ischemic episodes. It is also beneficial in preventing future attacks, improving exercise tolerance, and enhancing the overall quality of life in patients with chronic stable angina.\n\nComposition\n\nEach tablet contains:\n\nNicorandil IP – 5 mg\n\nExcipients – q.s.\n\nNicorandil tablets are available in film-coated form to ensure stability, easy swallowing, and optimal absorption. They are manufactured in compliance with Good Manufacturing Practices (GMP) standards to ensure safety, purity, and efficacy.\n\nPharmacological Action / Mechanism of Action\n\nNicorandil exhibits a dual mechanism that makes it distinct among anti-anginal drugs:\n\nNitrate-Like Effect:\nNicorandil acts as a nitric oxide (NO) donor. Nitric oxide activates guanylate cyclase, increasing cyclic GMP (cGMP) levels in vascular smooth muscle. This leads to relaxation of blood vessels, particularly veins and large arteries, thereby reducing preload and afterload on the heart. This nitrate-like activity lowers myocardial oxygen demand.\n\nPotassium Channel Opening Effect:\nNicorandil opens ATP-sensitive potassium (KATP) channels in vascular smooth muscle, resulting in arteriolar vasodilation. This increases coronary blood flow and improves oxygen supply to ischemic heart tissues.\n\nTogether, these effects reduce cardiac workload, enhance coronary perfusion, and prevent anginal pain by correcting the oxygen supply-demand mismatch in the heart muscle.\n\nUses and Indications\n\nNicorandil Tablets 5 mg are indicated for the treatment and prevention of angina pectoris in adults, particularly:\n\nChronic Stable Angina:\n\nHelps reduce the frequency and severity of chest pain associated with exertion or emotional stress.\n\nProphylaxis of Angina Attacks:\n\nUsed regularly to prevent anginal episodes, especially in patients with known coronary artery disease.\n\nAdjunct Therapy in Ischemic Heart Disease (IHD):\n\nCan be used alongside beta-blockers, calcium channel blockers, or antiplatelet drugs for enhanced symptom control and long-term protection.\n\nImprovement of Exercise Tolerance:\n\nReduces the likelihood of anginal pain during physical activity, enabling patients to perform daily tasks comfortably.\n\nIn some clinical cases, Nicorandil is also considered for post-myocardial infarction recovery, as it improves coronary perfusion, although this is at the discretion of a cardiologist.\n\nDosage and Administration\n\nRecommended Starting Dose: 5 mg to 10 mg twice daily.\n\nMaintenance Dose: May be increased gradually to 10–20 mg twice daily, depending on clinical response and tolerance.\n\nThe tablets should be swallowed whole with water, preferably at the same times each day.\n\nNicorandil should not be stopped abruptly; dosage tapering is recommended to avoid rebound angina.\n\nAlways follow the dosage instructions provided by the physician.\n\nKey Benefits\n\nDual Mechanism for Comprehensive Relief:\nCombines nitrate-like and potassium channel-opening properties for both arterial and venous dilation, providing superior protection against anginal attacks.\n\nImproves Coronary Blood Flow:\nDilates coronary arteries, increasing oxygen delivery to ischemic myocardial tissues.\n\nReduces Cardiac Workload:\nBy decreasing preload (venous return) and afterload (arterial resistance), Nicorandil minimizes the heart’s oxygen consumption.\n\nRapid Onset of Action:\nNicorandil acts within a short duration, offering quick relief from anginal discomfort.\n\nPrevents Future Angina Episodes:\nRegular use helps maintain steady control of chest pain, improving exercise capacity and quality of life.\n\nCompatible with Other Cardiac Medications:\nCan be safely used alongside antiplatelet agents, beta-blockers, ACE inhibitors, and statins as part of comprehensive cardiac care.\n\nFavorable Safety Profile:\nCompared to nitrates, Nicorandil carries a lower risk of tolerance development, making it suitable for long-term therapy.\n\nEnhances Myocardial Protection:\nNicorandil’s KATP channel activation provides additional cardioprotective effects by improving microvascular blood flow and limiting ischemic damage during stress.\n\nPrecautions and Warnings\n\nAlthough Nicorandil is generally well-tolerated, certain precautions are advised:\n\nHypotension:\nNicorandil may cause a drop in blood pressure due to vasodilation. Caution is advised in patients with hypotension or dehydration.\n\nConcurrent Use with Nitrates:\nShould not be used together with other nitrate medications to avoid severe hypotension.\n\nOral or Gastrointestinal Ulcers:\nRarely, Nicorandil may cause ulcerations in the mouth, intestines, or skin. Treatment should be discontinued if ulceration occurs.\n\nPatients with Low Blood Volume:\nUse cautiously in individuals with hypovolemia or those on diuretics.\n\nDriving and Machinery:\nDizziness or light-headedness may occur; avoid driving until effects are known.\n\nPregnancy and Lactation:\nShould be used only if prescribed by a physician when the potential benefits outweigh the risks.\n\nPossible Side Effects\n\nNicorandil is generally safe but may cause some side effects, particularly at the start of therapy or with higher doses. Common and rare adverse reactions include:\n\nCommon Side Effects:\n\nHeadache (due to vasodilation)\n\nFlushing or warmth sensation\n\nDizziness or light-headedness\n\nNausea or mild stomach upset\n\nFatigue or weakness\n\nLess Common / Rare Side Effects:\n\nHypotension (low blood pressure)\n\nPalpitations or tachycardia\n\nMouth ulcers, anal ulcers, or skin ulceration (uncommon but serious — discontinue if occurs)\n\nRash or allergic reaction\n\nVisual disturbances (rare and usually reversible)\n\nIf any severe reaction or persistent discomfort occurs, medical attention should be sought promptly.\n\nDrug Interactions\n\nAvoid concomitant use with nitrates or phosphodiesterase type-5 inhibitors (e.g., Sildenafil, Tadalafil), as it may cause a dangerous fall in blood pressure.\n\nCaution with antihypertensive drugs or diuretics, which may enhance hypotensive effects.\n\nAlcohol consumption can potentiate dizziness or hypotension and should be limited.\n\nStorage and Handling\n\nStore below 30°C, protected from moisture and direct sunlight.\n\nKeep out of reach of children.\n\nDo not use tablets past the expiry date or if the packaging is damaged.\n\nConclusion\n\nNicorandil Tablets 5 mg offer a modern and effective approach to managing angina pectoris, providing reliable relief through their dual-action mechanism. By combining nitrate-like vasodilation with potassium channel opening, Nicorandil ensures both oxygen supply improvement and reduction of cardiac workload — the cornerstone of angina management.\n\nIt is well-tolerated, fast-acting, and suitable for long-term therapy, making it a preferred choice for patients with chronic stable angina. Regular use under medical supervision helps reduce the frequency of chest pain, improve physical endurance, and enhance the overall quality of life in individuals with coronary artery disease.", "price": 381.0, "discountamount": 115.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2202, "imageuri": "https://productimages.withfloats.com/actual/69142c03b53db80943abd33d.png", "tileimageuri": "https://productimages.withfloats.com/tile/69142c03b53db80943abd33d.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-12T06:40:55.795Z", "updatedon": "2026-03-16T08:18:00.245Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//nicorandil-tablets-5mg/2202", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MAYORANDIL 5 ", "category": "CARDIOLOGYRANGE", "tags": [ "nicorandil tablets 5mg", "nicorandil 5 mg tablets uses", "nicorandil tablet 5mg benefits", "nicorandil 5mg medicine", "nicorandil tablets ip 5 mg", "what is nicorandil 5mg used for", "how does nicorandil tablet work", "nicorandil 5mg mechanism of action", "nicorandil tablets for angina treatment", "nicorandil tablet uses in heart disease", "nicorandil 5mg tablet price in india", "buy nicorandil 5mg tablets online", "nicorandil 5mg tablet brands", "nicorandil tablets manufacturer", "nicorandil tablets wholesale supplier" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6842b74dc10e9000933fa1d7", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "trelagliptin 50 mg", "description": "TRELAQWK 50 is a modern, once-a-week oral antidiabetic medication containing Trelagliptin 50mg, developed to support adults with type 2 diabetes mellitus (T2DM). This formulation is designed to improve blood glucose regulation while offering patients the convenience of weekly dosing. Created under rigorous quality standards, TRELAQWK 50 combines therapeutic effectiveness with enhanced compliance and lifestyle ease.\n\nActive Ingredient:\nTrelagliptin 50mg\nA next-generation DPP-4 (Dipeptidyl Peptidase-4) inhibitor with an extended half-life, enabling once-weekly administration. It helps improve glycemic control by preserving incretin hormones that naturally support insulin secretion and reduce glucagon production.\n\nKey Advantages:\nDelivers long-lasting blood sugar control with just one tablet per week\n\nEnhances insulin production and decreases glucagon levels in a glucose-dependent manner\n\nEffectively lowers both fasting and post-meal blood sugar levels\n\nPerfect for patients who find daily medications challenging\n\nLowers the risk of hypoglycemia when not combined with insulin or sulfonylureas\n\nContributes to better HbA1c levels over continued use\n\nMechanism of Action:\nTRELAQWK 50 functions by inhibiting the DPP-4 enzyme, which degrades incretin hormones like GLP-1 (Glucagon-Like Peptide-1) and GIP (Glucose-Dependent Insulinotropic Polypeptide). By preventing their breakdown, Trelagliptin extends the action of these hormones, resulting in increased insulin release and reduced glucagon levels. This mechanism is particularly effective after meals, helping maintain optimal blood glucose levels throughout the week.\n\nUsage Instructions:\nTake one tablet weekly, ideally on the same day each week\n\nCan be taken with or without meals\n\nSwallow whole with water—do not crush or chew\n\nFollow your doctor's dosing guidelines exactly\n\nIf you miss a dose, do not take two tablets together; speak with your doctor for guidance\n\nPossible Side Effects:\nTRELAQWK 50 is usually well-tolerated. 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It combines a blend of essential enzymes — Alpha Galactosidase, Lipase, Alpha Amylase, Protease, and Lactase — which help break down complex foods like carbohydrates, fats, proteins, and dairy products, making digestion easier and more efficient. PYLODIGEST is ideal for individuals suffering from bloating, gas, indigestion, or enzyme deficiencies.\n\nKey Benefits\nPromotes complete digestion of carbohydrates, fats, proteins, and lactose\n\nHelps relieve bloating, gas, and stomach discomfort\n\nSupports nutrient absorption for better overall health\n\nReduces symptoms of lactose intolerance\n\nEnhances digestive comfort after heavy meals\n\nSupports a healthy gut environment by preventing undigested food buildup\n\nHow Does It Work?\nPYLODIGEST works by supplementing the natural digestive enzymes produced by the body. 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