Home> Products> cyclic guanosine monophosphate

{ "products": [ { "_id": "6926f07d1a6e5ed700f07efd", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Ambrisentan 5mg, Tadalafil 20mg", "description": "Ambrisentan + Tadalafil (5mg + 20mg) is a combination medication primarily used to treat pulmonary arterial hypertension (PAH), a condition characterized by high blood pressure in the arteries of the lungs. This combination works through a synergistic dual mechanism of action to improve pulmonary vascular health and reduce the strain on the heart.\n\nAmbrisentan acts as an endothelin receptor antagonist, selectively blocking endothelin type A receptors. Endothelin is a naturally occurring substance that causes blood vessels to constrict, increasing blood pressure. By blocking these receptors, ambrisentan helps to relax and widen the pulmonary arteries, reducing vascular resistance and improving blood flow. Tadalafil, on the other hand, is a phosphodiesterase type 5 (PDE5) inhibitor that increases cyclic guanosine monophosphate (cGMP) levels, leading to vasodilation and enhanced blood flow. Together, these two drugs complement each other by reducing vessel constriction and promoting dilation, effectively lowering pulmonary arterial pressure and helping the right side of the heart pump more efficiently.​\n\nThe key benefits of the Ambrisentan + Tadalafil combination include improved exercise capacity, better heart function, and reduced symptoms of PAH such as shortness of breath and fatigue. Clinical studies have demonstrated that this combination significantly improves hemodynamics—the dynamics of blood flow—by reducing pulmonary vascular resistance and improving right ventricular (RV) function and structure. It also helps enhance patients' quality of life by increasing their ability to perform physical activities.​\n\nWhile the combination is generally well tolerated, some side effects may occur. Common side effects include headache, nasal congestion, flushing, and swelling of the ankles or legs, which are typical of vasodilator therapies. Some patients may experience gastrointestinal symptoms such as nausea or indigestion. Less commonly, serious side effects such as liver enzyme elevation, hypotension (low blood pressure), or allergic reactions may occur. Patients should consult healthcare professionals before using this combination, especially those with low blood pressure, liver issues, or those taking nitrates due to potential interactions.​\n\nIn conclusion, Ambrisentan + Tadalafil (5mg + 20mg) provides an effective treatment option for patients with pulmonary arterial hypertension by combining two complementary mechanisms to relax and dilate pulmonary arteries, decrease vascular resistance, and improve heart function and exercise tolerance. Patients are advised to use this medication under medical supervision to ensure safety and monitor for possible side effects. This combination therapy represents a significant advancement in managing PAH and improving patient outcomes.​\nThis product is an important therapeutic option and should be integrated into a comprehensive PAH management plan that includes lifestyle modifications, regular monitoring, and adherence to prescribed treatment.", "price": 1800.0, "discountamount": 951.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2220, "imageuri": "https://productimages.withfloats.com/actual/6926f08fce3236cca23d19b7.jpeg", "tileimageuri": "https://productimages.withfloats.com/tile/6926f08fce3236cca23d19b7.jpeg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-26T12:20:13.462Z", "updatedon": "2025-12-04T13:28:01.095Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/ambrisentan-5mg-tadalafil-20mg/2220", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "AMBRISTAR 5 + DURA 20 ", "category": "cardiology", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "681b331b233d4ecb404fe2d7", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Isosorbide Mononitrate 10 mg", "description": "CARDULES ISMN 10 is a prescription medication formulated to effectively manage and prevent angina pectoris (chest pain) associated with coronary artery disease. This medicine contains Isosorbide Mononitrate (10 mg), a long-acting nitrate that helps reduce the frequency and severity of anginal episodes. It is commonly prescribed as part of a long-term treatment plan for individuals with stable angina and other cardiovascular conditions to improve heart efficiency and blood flow.\n\nKey Ingredients\nIsosorbide Mononitrate 10 mg\nIsosorbide Mononitrate is the active nitrate component in this medicine, known for its vasodilatory effects that relax blood vessels and ease the heart’s workload. It is a metabolite of isosorbide dinitrate and offers longer-lasting therapeutic benefits with fewer doses.\n\nKey Benefits\nPrevents Chest Pain (Angina): CARDULES ISMN 10 is effective in reducing the number and severity of angina attacks by improving blood flow to the heart muscle.\n\nImproves Blood Circulation: The vasodilatory action of Isosorbide Mononitrate widens the arteries and veins, facilitating better circulation and oxygen delivery.\n\nReduces Heart Workload: By dilating blood vessels, the medication decreases the heart's oxygen demand, allowing it to function more efficiently.\n\nEnhances Exercise Tolerance: Patients using this medication often experience an increase in exercise capacity, as the risk of angina during physical activity is significantly reduced.\n\nLong-Acting Relief: As a sustained nitrate, CARDULES ISMN 10 provides long-lasting protection against anginal attacks when taken regularly.\n\nHow Does It Work?\nIsosorbide Mononitrate works by releasing nitric oxide in the smooth muscle cells of blood vessels. This nitric oxide activates an enzyme called guanylate cyclase, which increases cyclic guanosine monophosphate (cGMP). The rise in cGMP levels leads to the relaxation of vascular smooth muscles, causing vasodilation. This process reduces the amount of work the heart must do and lowers myocardial oxygen consumption. As a result, blood flows more easily, and the frequency of chest pain episodes is reduced. This mechanism makes CARDULES ISMN 10 a highly effective drug in the prevention of angina.\n\nDirections for Use\nTake CARDULES ISMN 10 strictly as prescribed by your doctor.\nIt is typically taken once or twice daily, depending on the severity of the condition and the prescribing physician's guidance.\nSwallow the tablet whole with a glass of water, preferably on an empty stomach or as directed.\nDo not crush, chew, or break the tablet, as it may interfere with the drug’s effectiveness.\nFor best results, take it at the same time each day to maintain consistent blood levels.\nAvoid abrupt discontinuation of the medication unless advised by your healthcare provider.\n\nSide Effects\nWhile CARDULES ISMN 10 is generally well-tolerated, some individuals may experience side effects, especially when starting treatment or adjusting dosage. Common and less serious side effects include:\n\nHeadache\n\nDizziness or light-headedness\n\nFlushing (warmth, redness, or tingly feeling under the skin)\n\nNausea\n\nFatigue\n\nIn rare cases, more serious side effects may occur, such as:\n\nSevere hypotension (low blood pressure)\n\nFainting\n\nIrregular heartbeat\n\nAllergic reactions like rash, itching, or swelling\n\nIf any severe or unusual side effects occur, seek immediate medical attention. Regular monitoring and dose adjustments may help manage and minimize side effects.", "price": 25.0, "discountamount": 8.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": [ "commonly prescribed", "effectively manage", "angina directions", "medication decreases", "angina attacks", "stable angina", "dose adjustments", "rash itching", "rare cases", "tingly feeling", "headache dizziness", "generally welltolerated", "cardules ismn 10", "drugs effectiveness", "crush chew", "empty stomach", "water preferably", "daily depending", "process reduces", "anginal attacks", "longlasting protection", "physical activity", "exercise capacity", "veins facilitating", "vasodilatory action", "hearts workload", "cardiovascular conditions", "helps reduce", "vasodilatory effects", "starting treatment", "isosorbide dinitrate", "anginal episodes", "longacting nitrate", "side effects", "blood vessels", "experience side effects", "prescription medication formulated", "minimize side effects", "highly effective drug", "improve heart efficiency", "dilating blood vessels", "relax blood vessels", "chest pain episodes", "isosorbide mononitrate widens", "active nitrate component", "longterm treatment plan", "result blood flows", "improving blood flow", "skin nausea fatigue", "adjusting dosage common", "cgmp levels leads", "nitric oxide activates", "smooth muscle cells", "releasing nitric oxide", "coronary artery disease" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2105, "imageuri": "https://productimages.withfloats.com/actual/681b331ec4193dc2e4e9a77a.png", "tileimageuri": "https://productimages.withfloats.com/tile/681b331ec4193dc2e4e9a77a.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-05-07T10:16:59.84Z", "updatedon": "2025-11-25T09:21:15.124Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/isosorbide-mononitrate-10-mg/2105", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Steris Healthcare Pvt. Ltd.", "category": "CARDIOLOGYRANGE", "tags": [ "Isosorbide Mononitrate 10 mg Uses in Hindi", "Isosorbide 10 mg uses", "Isosorbide mononitrate 120 mg" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6666c17bc6406f17e8a38522", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Tadalafil 20mg", "description": "STERIS DURA 20 \nTadalafil 20mg\nIntroduction\n\nSexual health is an essential part of overall well-being, confidence, and quality of life. Conditions such as erectile dysfunction (ED) can affect men physically and emotionally, often leading to stress, relationship challenges, and reduced self-esteem. STERIS DURA 20, containing Tadalafil 20mg, is a clinically proven medication designed to help men regain sexual confidence by improving erectile function in a safe and effective manner.\n\nManufactured by Steris Healthcare, STERIS DURA 20 is formulated to provide long-lasting relief from erectile dysfunction, allowing greater flexibility, spontaneity, and satisfaction. This comprehensive guide explains the product description, uses, key benefits, possible side effects, and important safety information in a clear and easy-to-understand way.\n\nProduct Description: STERIS DURA 20\n\nSTERIS DURA 20 is an oral tablet containing Tadalafil 20mg, a well-established Phosphodiesterase Type-5 (PDE5) inhibitor. Tadalafil works by improving blood flow to specific areas of the body, particularly the penile tissues, helping men achieve and maintain a firm erection during sexual stimulation.\n\nWhat makes Tadalafil unique compared to many other erectile dysfunction treatments is its long duration of action. A single dose of STERIS DURA 20 can remain effective for up to 36 hours, offering a broader window of opportunity for intimacy without the need for strict timing.\n\nSteris Healthcare ensures that STERIS DURA 20 is manufactured following high pharmaceutical quality standards, making it a reliable and trusted choice for long-term use when prescribed by a healthcare professional.\n\nUses of Tadalafil 20mg (STERIS DURA 20)\n\nSTERIS DURA 20 is primarily used for the treatment of erectile dysfunction (ED) in adult men. However, Tadalafil also has additional therapeutic uses under medical supervision.\n\n1. Erectile Dysfunction (ED)\n\nThe primary use of Tadalafil 20mg is to help men who have difficulty achieving or maintaining an erection sufficient for sexual activity. By improving blood flow to the penis, it supports natural erectile response during sexual stimulation.\n\n2. Benign Prostatic Hyperplasia (BPH)\n\nTadalafil is also used in the management of urinary symptoms associated with an enlarged prostate, such as weak urine stream, frequent urination, and difficulty in starting urination.\n\n3. Erectile Dysfunction Associated with BPH\n\nIn some patients, STERIS DURA 20 helps address both erectile dysfunction and urinary symptoms simultaneously, improving overall quality of life.\n\nHow STERIS DURA 20 Works\n\nTadalafil 20mg works by targeting the PDE5 enzyme, which is responsible for breaking down a chemical called cyclic guanosine monophosphate (cGMP). During sexual arousal, cGMP helps relax smooth muscles and increase blood flow in the penile tissues.\n\nBy inhibiting PDE5:\n\ncGMP levels remain elevated\n\nBlood vessels stay relaxed\n\nBlood flow improves\n\nA stronger and longer-lasting erection is achieved\n\nIt is important to note that STERIS DURA 20 does not cause automatic erections. Sexual stimulation is necessary for the medicine to work effectively.\n\nKey Benefits of STERIS DURA 20\n1. Long-Lasting Effect\n\nOne of the biggest advantages of Tadalafil 20mg is its long duration of action, which can last up to 36 hours. This allows greater spontaneity compared to short-acting alternatives.\n\n2. Improved Sexual Confidence\n\nBy providing reliable erectile support, STERIS DURA 20 helps reduce performance anxiety and restores confidence in intimate relationships.\n\n3. Flexible Usage\n\nSTERIS DURA 20 can be taken with or without food and does not require precise timing before sexual activity.\n\n4. Dual Benefit for Urinary Symptoms\n\nIn men with BPH, Tadalafil helps relax smooth muscles in the prostate and bladder, improving urinary flow.\n\n5. Trusted Quality from Steris Healthcare\n\nManufactured by Steris Healthcare, the product is designed to meet quality, safety, and effectiveness standards.\n\nDosage and Administration\n\nThe usual recommended dose is one tablet of STERIS DURA 20 (Tadalafil 20mg) as advised by a doctor.\n\nIt is generally taken 30 to 60 minutes before sexual activity.\n\nDo not take more than one tablet in 24 hours.\n\nThe tablet should be swallowed whole with water.\n\nDosage may vary based on individual health conditions and response to treatment.\n\nPossible Side Effects of Tadalafil 20mg\n\nLike all medications, STERIS DURA 20 may cause side effects in some individuals. Most side effects are mild and temporary.\n\nCommon Side Effects\n\nHeadache\n\nFlushing (warm sensation in the face)\n\nNasal congestion\n\nIndigestion\n\nBack pain\n\nMuscle aches\n\nMild dizziness\n\nThese effects usually subside as the body adjusts to the medication.\n\nLess Common but Serious Side Effects\n\nSudden vision or hearing loss\n\nChest pain\n\nIrregular heartbeat\n\nSevere dizziness or fainting\n\nProlonged erection lasting more than 4 hours (priapism)\n\nSeek immediate medical attention if any serious symptoms occur.\n\nPrecautions and Warnings\n\nSTERIS DURA 20 should not be used with nitrate medicines used for chest pain.\n\nPatients with heart disease, low blood pressure, liver or kidney disorders should consult a doctor before use.\n\nAvoid excessive alcohol consumption, as it may increase side effects.\n\nNot recommended for women or individuals under 18 years of age.\n\nAlways inform your doctor about other medications you are taking.\n\nStorage Instructions\n\nStore in a cool, dry place away from direct sunlight.\n\nKeep out of reach of children.\n\nDo not use after the expiry date.\n\nConclusion\n\nSTERIS DURA 20 (Tadalafil 20mg) is a safe, effective, and long-acting solution for men experiencing erectile dysfunction. Its ability to improve blood flow, support natural sexual response, and provide extended duration makes it a preferred choice for many patients. In addition to improving erectile function, it offers added benefits for urinary symptoms related to prostate enlargement.\n", "price": 365.0, "discountamount": 110.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "Call", "cGMP", "body", "food", "drugs", "penis", "ORDER", "Email", "class", "Usage", "enzyme", "doctor", "Action", "alcohol", "Studies", "queries", "nitrates", "WhatsApp", "priapism", "headache", "concerns", "Mechanism", "impotence", "back pain", "relaxation", "medication", "Conclusion", "blood flow", "information", "indigestion", "STERIS DURA", "muscle pain", "individuals", "20mg dosage", "Precautions", "sterispharma", "sterisonline", "Effectiveness", "heart problems", "Tadalafil 20mg", "penile tissues", "smooth muscles", "sexual activity", "PDE5) inhibitors", "nasal congestion", "grapefruit juice", "increased levels", "erectile function", "medical condition", "sudden vision loss", "sexual stimulation", "dosage instructions", "individual response", "prolonged erections", "effective treatment", "medical supervision", "Common side effects", "erectile dysfunction", "Serious side effects", "healthcare professional", "phosphodiesterase type 5", "various underlying causes", "cyclic guanosine monophosphate" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1646, "imageuri": "https://productimages.withfloats.com/actual/6666c17e475de163fe8832c7.png", "tileimageuri": "https://productimages.withfloats.com/tile/6666c17e475de163fe8832c7.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-10T09:03:55.945Z", "updatedon": "2025-12-17T12:50:40.143Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/steris-dura-20-/1646", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "STERIS DURA 20 ", "category": "UROLOGYRANGE", "tags": [ "STERIS DURA 20 mg", "Tadalafil 20mg", "", "tadalafil 20mg price", "", "tadalafil 20 mg tablet uses", "", "tadalafil गोली", "", "tadalafil 20 mg side effects", "", "tadalafil 20mg dosage", "Sexual health", "STERIS DURA 20 helps address both erectile dysfunction and urinary symptoms simultaneously", "Long-Lasting Effect" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6666b9a99f460208a41a62d2", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "tadalafil and dapoxetine tablets", "description": "DAPOXETINE LONG \nDAPOXITIME LONG is a potent combination tablet containing Tadalafil 10mg and Dapoxetine 30mg, crafted to tackle erectile dysfunction (ED) and premature ejaculation (PE) in men aged 18-64. This dual-action formula empowers men to achieve firmer erections, extend intercourse duration, and regain sexual confidence effectively. Designed for on-demand use, it offers a convenient solution for enhancing intimate experiences without daily dosing.​\n\nProduct Overview\nDAPOXETINE LONG stands out as an innovative pharmaceutical from Steris Healthcare, blending two clinically proven active ingredients into a single tablet. Tadalafil, a PDE5 inhibitor, relaxes penile blood vessels to boost blood flow during arousal, enabling strong, sustainable erections lasting up to 36 hours. Dapoxetine, a selective serotonin reuptake inhibitor (SSRI), modulates serotonin levels in the brain to delay ejaculation reflexes, providing better ejaculatory control.​\n\nThis synergistic pairing addresses the root causes of common male sexual challenges, making DAPOXITIME LONG ideal for men experiencing both ED and PE concurrently. Unlike single-ingredient treatments, it delivers comprehensive results in one easy-to-swallow tablet, typically taken 1-3 hours before anticipated sexual activity with water. Available through trusted pharmacies like Steris Online, it prioritizes discretion and efficacy for modern lifestyles.​\n\nKey Uses\nDAPOXITIME LONG primarily treats erectile dysfunction, where men struggle to attain or maintain an erection sufficient for satisfactory intercourse. It also effectively manages premature ejaculation, defined as ejaculation occurring sooner than desired, often within one minute of penetration.​\n\nBeyond core indications, the medication enhances overall sexual stamina, allowing couples to enjoy prolonged intimacy without performance pressure. Men with mixed symptoms find it particularly valuable, as it restores natural sexual rhythms and fosters deeper partner satisfaction. Clinical data supports its role in reducing related distress, making it a go-to for revitalizing bedroom dynamics.​\n\nMechanism of Action\nTadalafil inhibits phosphodiesterase type 5 (PDE5) enzymes, preventing cyclic guanosine monophosphate (cGMP) breakdown. This promotes smooth muscle relaxation in the corpus cavernosum, facilitating increased arterial inflow and reduced venous outflow for robust erections upon stimulation.​\n\nDapoxetine rapidly absorbs into the bloodstream, peaking within 1-2 hours, to elevate synaptic serotonin. This heightens sensory thresholds and prolongs intravaginal ejaculatory latency time (IELT) by 2-3 fold, as shown in phase 3 trials. The combination ensures Tadalafil's prolonged window aligns seamlessly with Dapoxetine's quick-onset control, optimizing dual benefits without interference.​\n\nKey Benefits\nSuperior Erection Quality: Tadalafil delivers reliable, long-lasting hardness, outperforming shorter-acting alternatives for spontaneous encounters.​\n\nExtended Intercourse Duration: Dapoxetine significantly boosts IELT, transforming brief encounters into fulfilling sessions averaging 3-4 times longer.​\n\nBoosted Confidence: Dual relief from ED and PE alleviates anxiety, enhancing self-esteem and relationship intimacy.​\n\nConvenience and Flexibility: On-demand dosing up to 36 hours of readiness eliminates rigid schedules, fitting busy lives seamlessly.​\n\nPartner Satisfaction: Improved performance leads to mutual pleasure, strengthening emotional bonds and reducing interpersonal distress.​\n\nThese advantages position DAPOXETINE LONG as a game-changer, backed by pooled efficacy data showing consistent improvements across demographics.​\n\nDosage and Administration\nTake one DAPOXITIME LONG tablet orally with a full glass of water 1-3 hours prior to sexual activity. Avoid grapefruit juice, heavy meals, or alcohol, as they may delay absorption or amplify side effects. Do not exceed one tablet per 24 hours or use more than once daily.​\n\nStart with the standard 10mg Tadalafil/30mg Dapoxetine dose; healthcare providers may adjust based on response and tolerance. Sexual stimulation remains essential, as the medication enhances natural physiology rather than initiating arousal independently. Store in a cool, dry place away from children.​\n\nPotential Side Effects\nCommon mild effects include headache, dizziness, nausea, flushing, nasal congestion, and indigestion, often resolving as the body adjusts. Dapoxetine-specific reactions like fatigue, dry mouth, or insomnia occur in about 10-20% of users initially.​\n\nLess frequent but notable are blurred vision from Tadalafil or back pain or diarrhea from Dapoxetine. Rare serious issues like priapism (prolonged erection >4 hours), sudden vision/hearing loss, or severe allergic reactions (rash, swelling) demand immediate medical attention. Most resolve without intervention, but monitoring is advised during early use.​\n\nPrecautions and Contraindications\nAvoid if allergic to either component or with nitrates, riociguat, alpha-blockers, or severe heart/liver/kidney issues. Consult a doctor for a history of low blood pressure, seizures, depression, glaucoma, or bleeding disorders. Not for women, children under 18, or men over 64 without guidance.​\n\nLifestyle tips: Stay hydrated, limit alcohol to prevent orthostatic hypotension, and disclose all medications to avoid interactions like with antifungals or HIV protease inhibitors. Regular checkups ensure safe, ongoing use.​\n\nConclusion\nDAPOXITIME LONG redefines male sexual wellness by merging Tadalafil's enduring erection support with Dapoxetine's precise ejaculation control, delivering unmatched performance gains. Men embracing this therapy report heightened satisfaction, confidence, and harmony in relationships, transforming intimacy from a concern to a strength. Prioritize professional consultation to tailor it to your health profile and unlock its full potential safely.​\n\n", "price": 355.0, "discountamount": 107.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "ED", "Call", "SSRI", "Email", "penis", "ORDER", "climax", "control", "WhatsApp", "erections", "Tadalafil", "blood flow", "information", "combination", "sterispharma", "sterisonline", "single tablet", "PDE5 inhibitor", "DAPOXITIME LONG", "Dapoxetine Long", "erectile dysfunction", "premature ejaculation", "comprehensive solution", "sexual health concerns", "selective serotonin reuptake inhibitor" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1636, "imageuri": "https://productimages.withfloats.com/actual/6666b9ac117f82c50b0351e7.png", "tileimageuri": "https://productimages.withfloats.com/tile/6666b9ac117f82c50b0351e7.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-10T08:30:33.181Z", "updatedon": "2025-12-18T07:57:35.962Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/tadalafil-and-dapoxetine-tablets/1636", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "DAPOXITIME LONG ", "category": "", "tags": [ "DAPOXITIME LONG", "Tadalafil (10mg)", "Dapoxetine (30mg)", "", "dapoxetine 30mg uses", "dapoxetine 30mg price in india", "", "dapoxetine 30mg uses in hindi", "", "dapoxetine 30mg side effects", "", "relaxes penile blood vessels to boost blood flow during arousal", "male sexual challenges.", "sexual activity .", "Partner Satisfaction." ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6661a73687f0960e14a2c739", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "mycophenolate sodium 360 mg", "description": "MYCOPLASM S 360 \nMycophenolate sodium 360 mg is an essential immunosuppressant medication designed to prevent organ transplant rejection, particularly for kidney, heart, and liver transplants. As the sodium salt of mycophenolic acid, it delivers 360 mg of the active moiety per tablet, providing targeted immune suppression to help patients maintain their new organs long-term. This product stands out for its enteric-coated formulation, which enhances gastrointestinal tolerability compared to other forms, making it a preferred choice in post-transplant care regimens.​\n\nUses of Mycophenolate Sodium 360 mg\nMycophenolate sodium 360 mg primarily serves as a prophylactic agent against acute rejection in adult and pediatric patients receiving allogeneic renal, cardiac, or hepatic transplants. It works alongside other immunosuppressants like cyclosporine and corticosteroids to create a balanced regimen that minimizes the risk of graft loss. Clinically, it proves effective in de novo transplant recipients, where starting therapy early post-surgery significantly reduces rejection episodes. Beyond transplants, off-label applications include managing refractory autoimmune conditions such as lupus nephritis or myasthenia gravis, where immune overactivity damages tissues.​\n\nThe drug targets the proliferation of T- and B-lymphocytes, key players in immune responses that can attack transplanted organs. In renal transplant patients, for instance, it helps preserve kidney function by curbing antibody-mediated rejection. Its role extends to maintenance therapy, where consistent dosing sustains immunosuppression without excessive toxicity. Healthcare providers often adjust it based on patient response and trough levels of the active metabolite, mycophenolic acid (MPA), ensuring optimal therapeutic outcomes.​\n\nKey Benefits of Mycophenolate Sodium 360 mg\nMycophenolate sodium 360 mg offers several advantages that make it a cornerstone in transplant medicine. One primary benefit is its selective inhibition of lymphocyte proliferation, sparing other cell types and reducing broad-spectrum immunosuppression risks. This leads to fewer opportunistic infections compared to older agents like azathioprine. The enteric coating minimizes upper GI upset, improving patient compliance—studies show higher adherence rates with this formulation.​\n\nEnhanced Graft Survival: Prolongs organ viability by effectively suppressing cell-mediated and humoral immunity, with clinical data showing reduced biopsy-proven rejection rates.\n\nImproved Tolerability: Lower incidence of nausea and diarrhea due to delayed-release technology, allowing twice-daily dosing without food restrictions.\n\nFlexible Dosing: Equivalent to 720 mg mycophenolate mofetil, but with predictable MPA exposure via enterohepatic recirculation for steady-state efficacy.\n\nPediatric Suitability: Approved for children over 2 years in renal transplants, supporting growth without compromising safety.\n\nCost-Effective Long-Term Option: Balances efficacy and side effect profile, potentially lowering overall healthcare costs from fewer rejections or hospitalizations.​\n\nPatients experience better quality of life, with sustained energy levels and fewer interruptions from acute rejection crises. Its metabolism to MPA via liver glucuronidation ensures reliable pharmacokinetics, even in patients with mild renal impairment.​\n\nSide Effects of Mycophenolate Sodium 360 mg\nWhile highly effective, mycophenolate sodium 360 mg carries risks typical of immunosuppressants, necessitating vigilant monitoring. Common adverse effects stem from its impact on rapidly dividing cells, particularly in the gut and bone marrow.\n\nCommon Side Effects\nGastrointestinal issues like diarrhea, nausea, vomiting, and abdominal pain, affecting up to 30-50% of users.\n\nHeadache, insomnia, and tremor, often mild and transient.\n\nInfections such as urinary tract or respiratory, due to moderated immunity.\n\nHypertension or peripheral edema, manageable with supportive care.\n\nLeukopenia or anemia, requiring periodic blood counts.​\n\nSerious Side Effects\nSevere myelosuppression leading to neutropenia or thrombocytopenia, which can increase infection or bleeding risks.\n\nProgressive multifocal leukoencephalopathy (PML), a rare brain infection linked to JC virus reactivation.\n\nGastrointestinal perforation or bleeding, especially in at-risk patients.\n\nIncreased malignancy risk, including lymphoma or skin cancers, over long-term use.\n\nHypersensitivity reactions like rash or anaphylaxis.​\n\nRegular complete blood counts, viral monitoring (e.g., CMV, BK virus), and skin exams mitigate these risks. Dose reductions or discontinuation may be needed if counts drop significantly.​\n\nMechanism of Action\nMycophenolate sodium 360 mg rapidly hydrolyzes to mycophenolic acid (MPA), a potent, reversible, non-competitive inhibitor of inosine-5'-monophosphate dehydrogenase (IMPDH). This enzyme catalyzes the rate-limiting step in de novo guanine nucleotide synthesis, depleting guanosine nucleotides essential for T- and B-cell DNA replication. Lymphocytes, reliant on this pathway, undergo proliferation arrest, suppressing both cell-mediated immunity and antibody production.​\n\nMPA also hinders glycosylation of adhesion molecules on lymphocytes and monocytes, impeding their migration to graft sites. It reduces nitric oxide production in macrophages without affecting endothelial cells, curbing inflammation. Enterohepatic recirculation of the glucuronide metabolite (MPAG) prolongs MPA exposure, enhancing efficacy. Protein binding to albumin (around 97%) ensures targeted delivery, with clearance primarily renal for the inactive form.​\n\nDosage and Administration Guidelines\nStandard dosing for renal transplant is 720 mg (two 360 mg tablets) twice daily, starting within 72 hours post-surgery. Adjustments occur for hepatic or cardiac transplants, often alongside cyclosporine. Therapeutic drug monitoring of MPA AUC (area under curve) optimizes levels between 30-60 mcg·h/mL. Take on an empty stomach for best absorption, though food has minimal impact due to the coating.​\n\nPrecautions and Warnings\nAvoid in pregnancy (Category D) due to teratogenicity—use contraception and regular pregnancy tests. Contraindicated in active untreated infections. Monitor for GI bleeding in ulcerative colitis patients. Drug interactions with antacids, cholestyramine, or rifampin alter MPA levels. Live vaccines are prohibited.​\n\nConclusion\nMycophenolate sodium 360 mg represents a vital advancement in transplant immunosuppression, offering robust protection against rejection with a favorable benefit-risk profile. Its targeted action on lymphocytes, combined with improved GI tolerance, empowers patients to thrive post-transplant. By integrating it into comprehensive regimens with close monitoring, healthcare teams maximize graft success and patient well-being. Always consult a specialist for personalized guidance to harness its full potential safely.\nEmail: info@sterispharma.com / contact@sterispharma.com\nCall/WhatsApp: 7877551268, 7849827488\nORDER Now: \nhttps://www.sterisonline.com/product/mycoplasm-s-360-133670\n\n\n\n\n\n\n", "price": 767.0, "discountamount": 567.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "dose", "risk", "body", "part", "ORDER", "360mg", "Email", "cells", "dosage", "nausea", "vomiting", "schedule", "headache", "strength", "WhatsApp", "diarrhea", "activity", "rejection", "treatment", "infections", "supplements", "information", "MYCOPLASM S", "sterispharma", "sterisonline", "stomach pain", "blood counts", "immune system", "complications", "liver problems", "liver function", "other medications", "Regular monitoring", "medical conditions", "healthcare provider", "Common side effects", "Serious side effects", "white blood cell count", "potential drug interactions", "optimal therapeutic effects", "combination therapy regimen", "organ transplant recipients", "Mycophenolate Sodium therapy", "other immunosuppressive drugs" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1474, "imageuri": "https://productimages.withfloats.com/actual/6661a739c749b7962dbc08c6.jpg", "tileimageuri": "https://productimages.withfloats.com/tile/6661a739c749b7962dbc08c6.jpg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-06T12:10:30.488Z", "updatedon": "2025-12-04T07:44:09.122Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/mycophenolate-sodium-360-mg/1474", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MYCOPLASM S 360 ", "category": "Oncology", "tags": [ "MYCOPLASM S 360", "Mycophenolate sodium (360mg)", "Mycophenolate sodium 360 mg price", "Mycophenolate sodium 360 mg brands", "Mycophenolate sodium 360 mg side effects", "Myfortic 360 alternative", "Myfortic 500" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6661a57d8da3a81d5c6a17dd", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Mycophenolate mofetil 500mg", "description": "MYCOPLASM M 500\nMycophenolate mofetil (500mg)\nMycoplasm M 500 is a medication containing Mycophenolate Mofetil in a 500mg dose. Mycophenolate Mofetil is an immunosuppressive drug used to prevent rejection in organ transplantation, particularly kidney, heart, and liver transplants. It works by inhibiting the proliferation of T and B lymphocytes, which are involved in the immune response that leads to rejection.\n\nThis medication is typically prescribed in combination with other immunosuppressants as part of a comprehensive transplant treatment regimen. It is important to take Mycoplasm M 500 exactly as prescribed by your healthcare provider to ensure optimal therapeutic outcomes and to minimize the risk of rejection or other complications.\n\nCommon side effects of Mycophenolate Mofetil may include gastrointestinal disturbances such as nausea, vomiting, diarrhea, and abdominal pain. It can also increase the risk of infections due to its immunosuppressive effects. Patients should be monitored regularly by their healthcare provider while taking this medication to assess for any potential adverse effects and to adjust the dosage as needed.\n\nMycoplasm M 500 should not be used in pregnant women or those planning to become pregnant without consulting a healthcare professional, as it can cause harm to the developing fetus. Additionally, it may interact with other medications, so it is important to inform your doctor about all the medications you are currently taking before starting Mycoplasm M 500 therapy.For further information:\nEmail: info@sterispharma.com / contact@sterispharma.com\nCall/WhatsApp: 7877551268, 7849827488\nORDER Now: \n\n\n\n\nMycophenolate mofetil 500 mg stands as a cornerstone in modern immunosuppressive therapy, primarily designed to prevent organ transplant rejection in kidney, heart, and liver recipients. As a prodrug, it rapidly converts to its active form, mycophenolic acid (MPA), which selectively targets the proliferation of T and B lymphocytes—key players in immune responses that can attack transplanted organs. This medication, available in convenient 500 mg tablets, offers reliable protection against acute rejection episodes, making it an essential component in post-transplant regimens worldwide.​\n\nProduct Uses\nMycophenolate mofetil 500 mg finds its primary application in solid organ transplantation, where it helps maintain long-term graft survival. For kidney transplant patients, it is typically administered alongside corticosteroids and calcineurin inhibitors like cyclosporine or tacrolimus to suppress the immune system's overreaction to the new organ. In heart and liver transplants, it plays a similar role, reducing the incidence of rejection by inhibiting antibody production and cell-mediated immunity.​\n\nBeyond transplants, healthcare providers increasingly use mycophenolate mofetil 500 mg for various autoimmune conditions. It effectively manages lupus nephritis by curbing inflammation in the kidneys, showing superior efficacy over traditional therapies in preserving renal function. Rheumatoid arthritis patients benefit from its ability to dampen joint inflammation, while those with dermatomyositis or scleroderma experience reduced skin and muscle involvement. Off-label, it treats inflammatory bowel diseases like Crohn's disease and even certain skin disorders such as pemphigus vulgaris, where immune-mediated blistering threatens quality of life.​\n\nKey Benefits\nThe therapeutic advantages of mycophenolate mofetil 500 mg extend far beyond basic immunosuppression, offering patients enhanced outcomes and improved daily living.\n\nSuperior Graft Protection: Clinical data highlight reduced acute rejection rates by up to 50% when combined with standard regimens, leading to better long-term organ function and survival.​\n\nSelective Lymphocyte Targeting: By depleting guanosine nucleotides in T and B cells via inosine monophosphate dehydrogenase (IMPDH) inhibition, it spares other cell types, minimizing broad toxicity seen with older immunosuppressants.​\n\nAnti-Inflammatory Effects: MPA inhibits adhesion molecule glycosylation, preventing lymphocyte recruitment to inflamed sites, which alleviates symptoms in autoimmune flares.​\n\nOral Convenience: The 500 mg formulation allows flexible dosing—typically 1 gram twice daily—without the need for injections, improving patient adherence.​\n\nVersatility Across Conditions: Proven efficacy in lupus, vasculitis, and myositis expands its utility, often allowing steroid dose reduction and fewer relapses.​\n\nCardiovascular and Anticancer Potential: Emerging evidence suggests it delays graft atherosclerosis by reducing lipid oxidation and may hinder tumor progression in certain malignancies due to its impact on nucleotide synthesis.​\n\nThese benefits translate to fewer hospital readmissions, better quality of life, and cost savings in long-term care for transplant and autoimmune patients.​\n\nSide Effects\nWhile mycophenolate mofetil 500 mg provides robust immunosuppression, it carries risks typical of this drug class, necessitating vigilant monitoring.\n\nCommon side effects affect the gastrointestinal tract most prominently, with nausea, vomiting, diarrhea, and abdominal pain occurring in over 30% of users. These often improve with dose adjustments or enteric-coated alternatives, but hydration and antiemetics help manage them effectively.​\n\nHematologic issues like leukopenia, anemia, and thrombocytopenia arise due to bone marrow suppression, requiring regular complete blood counts—weekly initially, then monthly. Infections pose a significant threat, as suppressed immunity increases susceptibility to viral (e.g., CMV), bacterial, and fungal pathogens; prophylactic antivirals are standard.​\n\nLess frequent but notable effects include hypertension, tremor, insomnia, and elevated liver enzymes. Women face heightened risks of congenital malformations if used during pregnancy, mandating effective contraception and pregnancy testing. Rare severe reactions encompass progressive multifocal leukoencephalopathy (PML) from JC virus reactivation and hypersensitivity syndromes.​\n\nDosage and Administration Notes\nStandard dosing for renal transplants involves 1 gram (two 500 mg tablets) twice daily, starting within 72 hours post-surgery, with adjustments for renal impairment. Hepatic transplant patients may require higher initial doses due to metabolism differences. Always take on an empty stomach with water to optimize absorption, avoiding antacids that bind MPA.​\n\nPrecautions and Interactions\nPatients must avoid live vaccines, report fevers promptly, and undergo TB screening pre-treatment. Drug interactions with azathioprine, cholestyramine, or rifampin can alter levels, so pharmacists review regimens closely. Regular monitoring of MPA blood levels ensures therapeutic efficacy without toxicity.​\n\nConclusion\nMycophenolate mofetil 500 mg emerges as a transformative immunosuppressive agent, safeguarding transplanted organs and taming autoimmune storms with its precise mechanism of lymphocyte suppression and anti-inflammatory prowess. By delivering key benefits like reduced rejection, versatile applications, and manageable administration, it empowers patients to reclaim normalcy post-transplant or amid chronic illness. Despite potential side effects, proactive monitoring and personalized dosing mitigate risks, underscoring its value in contemporary medicine. For those navigating transplant recovery or autoimmune challenges, this medication offers hope and stability, backed by decades of clinical validation.\n\n", "price": 775.0, "discountamount": 256.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "part", "Call", "harm", "risk", "Email", "heart", "ORDER", "nausea", "kidney", "dosage", "doctor", "vomiting", "WhatsApp", "Patients", "diarrhea", "rejection", "infections", "500mg dose", "combination", "information", "sterisonline", "proliferation", "B lymphocytes", "abdominal pain", "pregnant women", "immune response", "developing fetus", "other medications", "liver transplants", "other complications", "healthcare provider", "Common side effects", "organ transplantation", "Mycophenolate mofetil", "immunosuppressive drug", "Mycoplasm M 500 therapy", "healthcare professional", "other immunosuppressants", "immunosuppressive effects", "potential adverse effects", "optimal therapeutic outcomes", "gastrointestinal disturbances", "comprehensive transplant treatment regimen" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1472, "imageuri": "https://productimages.withfloats.com/actual/6661a57fdd39d2ccddbc3bb9.jpg", "tileimageuri": "https://productimages.withfloats.com/tile/6661a57fdd39d2ccddbc3bb9.jpg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-06T12:03:09.216Z", "updatedon": "2025-12-04T07:15:30.023Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/mycophenolate-mofetil-500mg/1472", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MYCOPLASM M 500", "category": "NEPHROLOGYRANGE", "tags": [ "MYCOPLASM M 500", "Mycophenolate mofetil (500mg)", "Mycophenolate mofetil 500 mg tablet", "Mycophenolate mofetil 500 mg price", "Mycophenolate mofetil 500 mg dosage", "Mycophenolate mofetil uses", "Mycophenolate mofetil side effects", "" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "693c0c9c0c30ac5c9f8203b4", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Isosorbide Mononitrate IP 30mg Tablets", "description": "CARDULES ISMN SR 30 tablets provide sustained-release Isosorbide Mononitrate IP 30mg, a nitrate medication designed for long-term management of angina in patients with coronary artery disease. This formulation from Steris Healthcare Pvt Ltd ensures steady vasodilation to improve heart blood flow and reduce chest pain episodes. It supports daily activities by minimizing oxygen demand on the heart muscle.​\nProduct Overview\nCARDULES ISMN SR 30 contains Isosorbide Mononitrate IP 30mg in a sustained-release matrix, allowing once-daily dosing for consistent therapeutic levels over 12-24 hours. The tablet's extended-release technology prevents peak-trough fluctuations common in immediate-release forms, promoting better patient compliance. Each film-coated tablet delivers precise bioavailability, with the active metabolite nitric oxide activating guanylate cyclase to boost cyclic GMP, relaxing vascular smooth muscle primarily in veins.​\n\nThis mechanism reduces preload (venous return to the heart) and afterload (arterial resistance), easing cardiac workload without significantly affecting heart rate. Unlike short-acting nitrates for acute relief, CARDULES ISMN SR 30 targets prophylaxis in chronic stable angina, often prescribed alongside beta-blockers or calcium channel blockers. Available in strips of 10 tablets, it undergoes rigorous quality testing at Steris facilities to meet IP standards, ensuring purity and stability.​\n\nKey Uses\nCARDULES ISMN SR 30 primarily prevents angina pectoris in coronary artery disease, where narrowed vessels limit oxygen supply during exertion. Patients experience fewer chest pain attacks during walking, climbing stairs, or stress.​\n\nIt manages chronic stable angina by enhancing myocardial perfusion, suitable for long-term therapy in adults over 18. Healthcare providers may use it adjunctively for coronary spasm or post-myocardial infarction prophylaxis to stabilize symptoms.​\n\nIn select cases, it aids heart failure management by offloading the heart, though not as monotherapy. Always initiate under cardiology supervision with dose titration to tolerance.​\n\nMajor Benefits\nThe sustained-release profile offers 24-hour protection with single morning dosing, improving adherence and lifestyle quality for active patients. It boosts exercise tolerance by 20-30% in trials, allowing longer physical efforts without angina onset.​\n\nBy dilating vessels, it decreases ischemia risk, potentially lowering hospitalization rates for acute episodes. Compared to placebo, users report halved attack frequency within weeks, enhancing daily productivity and emotional well-being.​\n\nBenefit\tMechanism\tPatient Outcome\nAngina Prevention\tVasodilation reduces preload/afterload ​\tFewer attacks, better exertion capacity\nSteady Relief\tSR formulation maintains levels ​\tOnce-daily convenience, no fluctuations\nHeart Protection\tImproves O2 delivery ​\tReduced ischemia, enhanced QoL\nCompliance Boost\tSimple regimen ​\tHigher adherence vs multiple doses\nAdditional perks include minimal impact on blood pressure in normotensives and compatibility with anti-anginals, making it versatile in combo therapy.\n\nPotential Side Effects\nCommon effects include headache (dose-related, often transient in first week), dizziness, or flushing due to vasodilation—hydrate and rise slowly to manage. Gastrointestinal upset like nausea occurs in 5-10% initially.​\n\nOrthostatic hypotension risks fainting, especially early; avoid alcohol or other vasodilators. Rare serious issues encompass severe hypotension, tachycardia, or methemoglobinemia with overdose—monitor blood pressure regularly.​\n\nAllergic reactions (rash, itching) or vision changes warrant discontinuation. Contraindicated in hypotension, glaucoma, or recent PDE5 inhibitor use; caution in anemia or hypothyroidism.​\n\nDosage Guidelines\nStart with 30mg once daily upon waking, swallowed whole without crushing. Titrate to 60mg if tolerated after 3-7 days, max 120mg/day. Take on empty stomach for optimal absorption; avoid late dosing to prevent nocturnal headaches.​\n\nAdjust for elderly or renal/hepatic impairment. Tolerance may develop—nitrate-free interval (evening) helps sustain efficacy. Store below 30°C.​\nConclusion\nCARDULES ISMN SR 30 empowers angina patients with reliable, once-daily prevention, restoring confidence in routine activities under Steris Healthcare's quality assurance. Its targeted vasodilation balances efficacy and tolerability for sustained heart health", "price": 65.0, "discountamount": 19.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2243, "imageuri": "https://productimages.withfloats.com/actual/693c0ca6391a3fa44b0608d8.png", "tileimageuri": "https://productimages.withfloats.com/tile/693c0ca6391a3fa44b0608d8.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-12T12:37:48.92Z", "updatedon": "2025-12-12T12:37:48.92Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/isosorbide-mononitrate-ip-30mg-tablets/2243", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CARDULES ISMN SR 30", "category": "", "tags": [ "Isosorbide Mononitrate IP 30mg Tablets", "coronary artery disease", "heart blood flow and reduce chest pain episodes", "oxygen demand on the heart muscle", "relaxing vascular smooth muscle primarily in veins" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "693c0a0eb7439f8802544bc8", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "RIBAVIRIN CAPSULES IP 100mg", "description": "REBATERIS 100 contains Ribavirin IP 100mg in a hard gelatin capsule filled with white to off-white powder for optimal stability and bioavailability. Each pack typically includes 30 capsules, designed for oral administration with food to enhance absorption and reduce gastrointestinal upset. Ribavirin, a synthetic guanosine nucleoside analog, interferes with viral RNA polymerase and mRNA capping, halting hepatitis C virus (HCV) replication at multiple stages. This broad-spectrum antiviral also shows activity against respiratory syncytial virus (RSV) in select pediatric cases, though its primary indication remains HCV genotype management.​\n\nThe 100mg strength allows for weight-based dosing adjustments, making REBATERIS 100 suitable for adults and children over 3 years under specialist supervision. Unlike higher 200mg capsules, it supports finer dose reductions during therapy to manage side effects, ensuring better tolerability. Stored at room temperature away from moisture, it maintains potency for extended shelf life, aligning with pharmacopeial standards for purity and dissolution.​\n\nKey Uses\nREBATERIS 100 treats chronic hepatitis C virus infection in combination therapies, particularly for patients ineligible for all-oral direct-acting antivirals. It boosts sustained virologic response rates when paired with pegylated interferon alfa, addressing genotypes 1 through 6 based on regional guidelines.​\n\nIn severe RSV lower respiratory tract infections, off-label use occurs in hospitalized infants, where aerosolized forms predominate, but oral REBATERIS 100 contributes to interferon combos for immunocompromised children. It curbs viral load, prevents liver fibrosis progression, and reduces cirrhosis risk, making it essential for long-term liver preservation.​\n\nAdditionally, emerging evidence supports its adjunct role in certain hemorrhagic fevers like Lassa virus, though availability limits widespread application. Always initiated by hepatologists, treatment durations span 24-48 weeks depending on genotype, viral load, and response milestones.​\n\nMajor Benefits\nREBATERIS 100 enhances viral clearance, achieving up to 50-80% sustained response rates in interferon combinations, significantly lowering hepatocellular carcinoma risk over five years. Patients experience normalized liver enzymes and fibrosis regression on biopsy follow-up.​\n\nIts oral capsule form simplifies adherence compared to injectables, with twice-daily dosing fitting daily routines. The 100mg potency permits precise titration—e.g., 800-1400mg daily divided—for personalized therapy, minimizing excess exposure in lighter patients.​\n\nLong-term, it preserves liver function, averting transplants and improving quality of life metrics like fatigue reduction and work productivity. Cost-effective for resource-limited settings, REBATERIS 100 bridges gaps until pan-genotypic regimens become accessible.​\nBenefit\tMechanism\tClinical Impact\nViral Suppression\tRNA polymerase inhibition ​\t>50% SVR in combos ​\nLiver Protection\tFibrosis halt ​\tReduced cirrhosis by 30-40%\nFlexible Dosing\t100mg increments ​\tBetter tolerability, adherence\nBroad Genotype Coverage\tMulti-genotype efficacy ​\tVersatile for diverse patients\nPotential Side Effects\nCommon side effects include hemolytic anemia, peaking at weeks 4-8, necessitating hemoglobin monitoring and dose cuts to 600mg daily if levels drop below 10g/dL. Fatigue, headache, and insomnia affect over 40% of users, often resolving post-therapy.​\n\nGastrointestinal issues like nausea, diarrhea, and anorexia occur in 20-30%, mitigated by food intake. Dermatologic reactions—rash, pruritus—or flu-like symptoms from interferon pairing demand vigilance. Teratogenicity risks are high; dual contraception is mandatory for 6 months post-treatment due to sperm/ovum mutagenicity.​\n\nSerious risks encompass pulmonary infiltrates, cardiac ischemia in vulnerable patients, and thyroid dysfunction. Avoid in hemoglobinopathies, severe renal impairment (CrCl <50mL/min), or pregnancy. Regular blood counts and ophthalmologic exams guide safe continuation.​\n\nDosage Guidelines\nDosing is weight-based: adults <75kg receive mg/day (10 capsules: 5 AM, 5 PM); ≥75kg get 1200 mg/day (12 capsules: 6 AM, 6 PM), swallowed whole with meals. Pediatrics (≥3 years): 15mg/kg/day divided BID, rounded to the nearest 100mg via REBATERIS 100 capsules.​\n\nReduce by 200-400mg for anemia or neutropenia; discontinue if unresolved. Duration: 48 weeks for genotype 1, 24 weeks for others, with viral load checks at week 12. Swallow intact; no crushing.​\nConclusion\nREBATERIS 100 empowers hepatitis C management with proven antiviral potency and dosing precision from Steris Healthcare. It transforms prognosis for countless patients, but demands specialist oversight amid monitoring needs", "price": 2900.0, "discountamount": 870.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2242, "imageuri": "https://productimages.withfloats.com/actual/693c0a151c130ff8f4cd2c93.png", "tileimageuri": "https://productimages.withfloats.com/tile/693c0a151c130ff8f4cd2c93.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-12T12:26:54.651Z", "updatedon": "2025-12-12T12:26:54.651Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/ribavirin-capsules-ip-100mg/2242", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "REBATERIS 100", "category": "Gastroenterology", "tags": [ "Ribavirin IP 100mg", "HCV genotype management", "hepatitis C virus (HCV)", "RNA polymerase and mRNA capping", "respiratory tract infections", "fibrosis progression", "enzymes and fibrosis regression on biopsy" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6937c92e461b07808ef722e4", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Cyclosporine 100mg", "description": "Cyclosporine, marketed under the brand name CYCLOPURE 100, is a potent immunosuppressant medication widely used in clinical settings to prevent organ transplant rejection and to manage various autoimmune disorders. Available as a 100mg oral capsule, CYCLOPURE 100 plays a critical role in modulating the immune system, helping patients maintain graft survival and control symptoms of immune-related diseases.\n\nProduct Description\nCYCLOPURE 100 contains cyclosporine, a cyclic polypeptide consisting of 11 amino acids, derived from the fungus Tolypocladium inflatum. It selectively inhibits the activity of T-lymphocytes, a subset of white blood cells that play a central role in immune response. By targeting these immune cells, cyclosporine helps prevent the body’s immune system from attacking transplanted organs, such as kidneys, liver, or heart, and reduces inflammation in autoimmune diseases.\n\nThe capsules are formulated for oral administration, with each capsule containing 100mg of cyclosporine. This dosage provides an effective balance between immunosuppression and safety for most adult patients, although dosing must be carefully tailored by healthcare providers based on patient response, therapeutic drug monitoring, and condition severity.\n\nUses of CYCLOPURE 100\nCYCLOPURE 100 is primarily indicated for the following medical purposes:\n\nPrevention of Organ Transplant Rejection: It is commonly prescribed to recipients of kidney, liver, heart, or other organ transplants to prevent acute and chronic rejection by suppressing immune responses that target the graft.\n\nAutoimmune Disease Management: Cyclosporine is effective in treating autoimmune disorders such as rheumatoid arthritis, psoriasis, and certain types of nephrotic syndrome. By reducing immune system overactivity, it helps alleviate symptoms such as joint inflammation, skin lesions, and kidney damage.\n\nSevere Atopic Dermatitis: In cases where conventional treatments are ineffective, cyclosporine may be used to control symptoms of severe eczema by modulating immune hyper-reactivity.\n\nOther Off-Label Uses: Occasionally, cyclosporine is used for other immune-mediated conditions like uveitis, Crohn’s disease, and some forms of lupus nephritis depending on physician discretion.\n\nKey Benefits\nEffective Immunosuppression: CYCLOPURE 100 is known for its potent ability to suppress immune responses selectively, significantly reducing the risk of organ rejection after transplantation and improving graft survival rates.\n\nVersatility in Autoimmune Conditions: Beyond organ transplantation, cyclosporine’s immunomodulatory effects provide relief in autoimmune diseases by controlling inflammation and immune overactivity that cause tissue damage.\n\nImprovement in Quality of Life: By controlling disease symptoms such as joint pain, skin inflammation, or kidney impairment, CYCLOPURE 100 enables patients to experience improved physical comfort and daily functioning.\n\nOral Administration Convenience: The capsule form ensures ease of use and better patient compliance compared to injectable immunosuppressants, allowing therapy to be managed on an outpatient basis.\n\nTherapeutic Drug Monitoring: The availability of blood level monitoring helps customize dosage and maximize therapeutic effects while minimizing toxicity.\n\nSide Effects and Precautions\nWhile CYCLOPURE 100 is highly beneficial, it carries a risk of side effects due to its immunosuppressive nature and systemic effects. Common, less severe side effects include:\n\nGingival hyperplasia (gum overgrowth)\n\nTremors or mild neurological symptoms\n\nHypertension (high blood pressure)\n\nIncreased hair growth (hypertrichosis)\n\nGastrointestinal disturbances (nausea, diarrhea)\n\nMore serious adverse effects, which require immediate medical attention, can include:\n\nNephrotoxicity: Cyclosporine can affect kidney function; regular monitoring of kidney function tests is essential.\n\nIncreased Risk of Infections: Suppression of the immune system increases vulnerability to bacterial, viral, and fungal infections.\n\nHepatotoxicity: Liver function should be monitored as cyclosporine may cause elevated liver enzymes or more severe liver damage.\n\nMalignancies: Long-term use has been associated with an increased risk of certain cancers, particularly lymphomas and skin cancers.\n\nElectrolyte Imbalances: Hypomagnesemia and hyperkalemia are possible and require monitoring.\n\nPatients must inform their healthcare providers about other medications they take, as cyclosporine has significant drug interactions that can affect its blood levels and toxicity risk, including with antibiotics, antifungals, anticonvulsants, and others.\n\nConclusion\nCYCLOPURE 100 (Cyclosporine 100mg) stands as a cornerstone immunosuppressant medication that plays a vital role in preventing organ rejection and managing autoimmune diseases. Its targeted immunosuppressive action effectively reduces disease burden, enhances graft survival, and improves patients’ quality of life. Although it entails risks of side effects, careful medical supervision, therapeutic drug monitoring, and adherence to prescribed dosing protocols effectively mitigate these concerns.\n\nFor patients undergoing organ transplantation or those with autoimmune conditions unresponsive to standard therapies, CYCLOPURE 100 provides a valuable therapeutic solution. Always consult a healthcare professional before starting or adjusting therapy with CYCLOPURE 100 to ensure the safest and most effective use tailored to individual clinical needs.", "price": 1014.0, "discountamount": 305.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2239, "imageuri": "https://productimages.withfloats.com/actual/6937c930ed26b2c06ce34f7e.jpeg", "tileimageuri": "https://productimages.withfloats.com/tile/6937c930ed26b2c06ce34f7e.jpeg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-09T07:01:02.399Z", "updatedon": "2025-12-09T07:01:02.399Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/cyclosporine-100mg/2239", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CYCLOPURE 100", "category": "NEUROLOGY RANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false } ], "hasmoreitems": false, "isapirequest": false, "totalresults": 27, "query": null, "floatingpoint": null }