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"name": "Glimepiride IP1 mg, Voglibose IP 0.2 MG & Metformin Hydrochloride IP 500 mg ",
"description": "GLIMITERIS MV1 0.2 is an advanced fixed-dose combination (FDC) medication designed for adults with Type 2 Diabetes Mellitus (T2DM) who require more than lifestyle modifications or single/dual therapy to maintain optimal blood sugar levels. This innovative formulation brings together the power of three well-established antidiabetic agents—Glimepiride (1 mg), Voglibose (0.2 mg), and Metformin Hydrochloride SR (500 mg)—to provide comprehensive glycemic control.\n\nIt is particularly effective for patients struggling with postprandial hyperglycemia, fasting glucose regulation, and HbA1c reduction, making it a preferred choice in cases of poorly controlled diabetes.\n\n \n\nMechanism of Action\nThe therapeutic benefit of GLIMITERIS MV1 0.2 comes from the unique synergy of its three components, each targeting different aspects of glucose metabolism:\n\n1. Glimepiride (1 mg) – Sulfonylurea\nStimulates insulin secretion by activating pancreatic beta cells.\n\nProvides a long-lasting effect with comparatively lower hypoglycemia risk than older sulfonylureas.\n\nHelps reduce both fasting and postprandial glucose levels.\n\n2. Voglibose (0.2 mg) – Alpha-Glucosidase Inhibitor\nDelays the breakdown and absorption of carbohydrates in the intestine.\n\nMinimizes post-meal glucose spikes (PPBG).\n\nActs locally in the gut and has minimal systemic absorption, which reduces systemic side effects.\n\n3. Metformin Hydrochloride SR (500 mg) – Biguanide\nDecreases hepatic glucose production (gluconeogenesis).\n\nImproves peripheral insulin sensitivity, enhancing glucose uptake in muscles.\n\nDoes not cause hypoglycemia on its own.\n\nThe sustained-release (SR) formulation ensures extended control and reduces gastrointestinal side effects.\n\n \n\nIndications\nGLIMITERIS MV1 0.2 is indicated for:\n\nAdults with Type 2 Diabetes Mellitus.\n\nPatients inadequately controlled with monotherapy or dual therapy.\n\nManagement of fasting and postprandial hyperglycemia.\n\nLong-term HbA1c reduction as part of a comprehensive diabetes care plan.\n\n \n\nKey Benefits\n✅ Comprehensive Blood Sugar Control – Acts on fasting, post-meal, and long-term HbA1c levels.\n✅ Postprandial Spike Management – Voglibose effectively controls carbohydrate-induced sugar surges.\n✅ Reduced Pill Burden – Combines three medicines into a single tablet.\n✅ Lower Hypoglycemia Risk – Metformin and Voglibose balance out Glimepiride’s insulin-secreting effect.\n✅ Weight Management Support – Metformin may promote modest weight loss or prevent weight gain.\n✅ Improved Tolerability – SR formulation of Metformin enhances gastrointestinal comfort.\n\n \n\nDosage and Administration\nRecommended dose: One tablet once or twice daily with meals, or as directed by the physician.\n\nAdministration tips:\n\nTake with the first bite of a main meal to maximize Voglibose’s effect.\n\nSwallow whole with water; do not crush or chew the SR tablet.\n\nDose adjustments: Based on blood sugar monitoring, clinical response, and renal/hepatic function.\n\n \n\nContraindications\nGLIMITERIS MV1 0.2 is not suitable for patients with:\n\nType 1 diabetes or diabetic ketoacidosis.\n\nSevere renal impairment (eGFR <30 mL/min/1.73 m²).\n\nHepatic dysfunction.\n\nSevere gastrointestinal diseases.\n\nHistory of lactic acidosis.\n\nHypersensitivity to Glimepiride, Voglibose, or Metformin.\n\nPregnancy and lactation (unless strictly advised by a physician).\n\n \n\nWarnings and Precautions\nHypoglycemia: Risk is higher when combined with other antidiabetics or with missed meals.\n\nLactic Acidosis: A rare but life-threatening effect of Metformin—renal function monitoring is essential.\n\nGI Side Effects: Voglibose and Metformin may cause bloating, flatulence, or diarrhea (usually temporary).\n\nVitamin B12 Monitoring: Long-term Metformin use may reduce B12 absorption.\n\nLiver and Kidney Function: Regular monitoring is recommended for safe long-term use.\n\n \n\nAdverse Effects\nCommon:\nGlimepiride: Mild hypoglycemia, dizziness, slight weight gain.\n\nVoglibose: Gas, abdominal discomfort, mild diarrhea.\n\nMetformin SR: Nausea, bloating, metallic taste, loose stools.\n\nRare but Serious:\nLactic acidosis (from Metformin).\n\nSevere hypoglycemia (especially if meals are skipped).\n\nAllergic reactions such as rash, itching, or swelling.\n\nElevated liver enzymes.\n\nSeek medical attention if symptoms such as rapid breathing, confusion, severe fatigue, or muscle pain occur.\n\n \n\nDrug Interactions\nIncreased hypoglycemia risk: With insulin, beta-blockers, and sulfonylureas.\n\nReduced Metformin efficacy: With corticosteroids, estrogens, and diuretics.\n\nLactic acidosis risk: Higher with alcohol or iodinated contrast agents. ",
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"description": "KETORENAL PREPROB 90B is a premium probiotic supplement specifically designed to support gut health, digestive function, and overall immune wellness. Formulated with a potent blend of Streptococcus Thermophilus, Lactobacillus Acidophilus, and Bifidobacterium Longum, this product helps restore and maintain the natural balance of healthy bacteria in the gastrointestinal tract. Ideal for individuals dealing with digestive discomfort, antibiotic-associated disturbances, or seeking to promote optimal kidney and metabolic health, this capsule-based supplement delivers reliable daily support.\n\n\nKey Benefits:\n\n\nHelps restore healthy gut flora, especially after antibiotic therapy\n\nSupports kidney and metabolic health, ideal for patients with renal complications\n\nEnhances digestive comfort by reducing bloating, gas, and irregular bowel movements\n\nBoosts natural immunity by strengthening the gut barrier and preventing harmful bacterial overgrowth\n\nPromotes nutrient absorption and assists in maintaining optimal intestinal pH.\n\nMay aid in managing chronic kidney disease (CKD) by reducing intestinal-derived toxins.\n\n\nHow Does It Work?\n\n\nKETORENAL PREPROB 90B works by delivering a balanced blend of live, beneficial bacteria to the gastrointestinal tract. These probiotics colonize the gut lining and perform several important functions:.\n\nStreptococcus Thermophilus helps break down lactose and promotes the production of beneficial enzymes and acids that prevent the growth of harmful microorganisms.\n\nLactobacillus Acidophilus maintains the acidic environment of the intestines, which helps inhibit the proliferation of pathogens and aids digestion.\n\nBifidobacterium Longum supports the immune system, reduces gut inflammation, and enhances the breakdown of dietary fiber into beneficial short-chain fatty acids.\n\nTogether, these strains improve the gut environment, reduce inflammation, and support healthy metabolism and kidney function.\n\n\nDirections for Use:.\n\n\nTake one capsule daily, or as directed by your healthcare provider.\n\nIt is best taken with or after meals for improved absorption and tolerance.\n\nDo not crush or chew the capsule; swallow it whole with water.\n\nStore in a cool, dry place, away from direct sunlight.\n\nRefrigeration is optional unless specified on the packaging, but helps maintain potency.\n\n\nSide Effects:.\n\n\nKETORENAL PREPROB 90B is generally well tolerated. However, some individuals may experience mild and temporary side effects, especially when first starting probiotic supplementation.\n\nCommon Side Effects:.\n\nGas.\n\nBloating.\n\nMild abdominal discomfort.\n\nThese effects typically subside as the body adjusts to the probiotic. If symptoms persist or worsen, consult your healthcare provider.\n\nRare Side Effects:.\n\nAllergic reactions (rash, itching, swelling).\n\nSevere gastrointestinal upset in immunocompromised individuals.\n\nAlways consult your physician before starting any new supplement, especially if you are pregnant, nursing, or have a chronic medical condition.",
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"description": "VELAXFINE XR 75 is an extended-release formulation of Venlafaxine Hydrochloride 75 mg, a well-established serotonin-norepinephrine reuptake inhibitor (SNRI) used primarily to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder (SAD), and panic disorder. With its gradual release mechanism, this medication helps maintain consistent therapeutic levels throughout the day, providing effective relief from mood and anxiety symptoms with reduced dosing frequency.\n\n\nKey Benefits:\n\n\nEffectively treats major depressive disorder (MDD).\n\nHelps manage generalized anxiety disorder (GAD) and panic attacks.\n\nReduces symptoms of social anxiety disorder (SAD).\n\nSupports emotional balance and improves mental clarity.\n\nPromotes better sleep, energy levels, and concentration.\n\nExtended-release formulation offers convenience and improved tolerability.\n\n\nHow Does It Work?\n\n\nVELAXFINE XR 75 works by increasing the levels of serotonin and norepinephrine, two natural chemicals in the brain that are crucial for maintaining mental balance. As an SNRI, Venlafaxine blocks the reabsorption (reuptake) of these neurotransmitters in the brain's synaptic clefts. By enhancing their availability, it helps improve mood, reduce anxiety, and alleviate emotional stress.\n\nThe extended-release formulation ensures a gradual and consistent release of the active ingredient over 24 hours, maintaining stable blood levels and reducing the risk of side effects such as nausea or dizziness that can occur with immediate-release forms.\n\n\nDirections for Use:.\n\n\nTake VELAXFINE XR 75 exactly as prescribed by your healthcare provider.\n\nUsually taken once daily, with food, to reduce the risk of gastrointestinal discomfort.\n\nSwallow the capsule whole with a glass of water-- do not crush, chew, or open the capsule.\n\nConsistency is key; take it at the same time each day.\n\nDo not suddenly stop taking this medication without medical advice, as it may lead to withdrawal symptoms.\n\nRegular follow-ups with your doctor are recommended to monitor progress and adjust dosage if necessary.\n\n\nSide Effects:.\n\n\nWhile VELAXFINE XR 75 is effective for many patients, it may cause side effects in some individuals.\n\nCommon Side Effects:.\n\nNausea or upset stomach.\n\nDrowsiness or insomnia.\n\nDry mouth.\n\nDizziness.\n\nSweating.\n\nLoss of appetite.\n\nIncreased blood pressure (especially at higher doses).\n\nSerious but Less Common Side Effects:.\n\nSuicidal thoughts or behavior (especially in young adults).\n\nSerotonin syndrome (confusion, rapid heartbeat, hallucinations).\n\nSeizures.\n\nEye pain or vision changes (angle-closure glaucoma).\n\nWithdrawal symptoms upon abrupt discontinuation (headache, mood swings, fatigue).\n\nNotify your doctor immediately if you experience mood changes, unusual behavior, or allergic reactions such as rash, swelling, or difficulty breathing.",
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