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"description": "CARDULES ISMN 10 is a prescription medication formulated to effectively manage and prevent angina pectoris (chest pain) associated with coronary artery disease. This medicine contains Isosorbide Mononitrate (10 mg), a long-acting nitrate that helps reduce the frequency and severity of anginal episodes. It is commonly prescribed as part of a long-term treatment plan for individuals with stable angina and other cardiovascular conditions to improve heart efficiency and blood flow.\n\nKey Ingredients\nIsosorbide Mononitrate 10 mg\nIsosorbide Mononitrate is the active nitrate component in this medicine, known for its vasodilatory effects that relax blood vessels and ease the heart’s workload. It is a metabolite of isosorbide dinitrate and offers longer-lasting therapeutic benefits with fewer doses.\n\nKey Benefits\nPrevents Chest Pain (Angina): CARDULES ISMN 10 is effective in reducing the number and severity of angina attacks by improving blood flow to the heart muscle.\n\nImproves Blood Circulation: The vasodilatory action of Isosorbide Mononitrate widens the arteries and veins, facilitating better circulation and oxygen delivery.\n\nReduces Heart Workload: By dilating blood vessels, the medication decreases the heart's oxygen demand, allowing it to function more efficiently.\n\nEnhances Exercise Tolerance: Patients using this medication often experience an increase in exercise capacity, as the risk of angina during physical activity is significantly reduced.\n\nLong-Acting Relief: As a sustained nitrate, CARDULES ISMN 10 provides long-lasting protection against anginal attacks when taken regularly.\n\nHow Does It Work?\nIsosorbide Mononitrate works by releasing nitric oxide in the smooth muscle cells of blood vessels. This nitric oxide activates an enzyme called guanylate cyclase, which increases cyclic guanosine monophosphate (cGMP). The rise in cGMP levels leads to the relaxation of vascular smooth muscles, causing vasodilation. This process reduces the amount of work the heart must do and lowers myocardial oxygen consumption. As a result, blood flows more easily, and the frequency of chest pain episodes is reduced. This mechanism makes CARDULES ISMN 10 a highly effective drug in the prevention of angina.\n\nDirections for Use\nTake CARDULES ISMN 10 strictly as prescribed by your doctor.\nIt is typically taken once or twice daily, depending on the severity of the condition and the prescribing physician's guidance.\nSwallow the tablet whole with a glass of water, preferably on an empty stomach or as directed.\nDo not crush, chew, or break the tablet, as it may interfere with the drug’s effectiveness.\nFor best results, take it at the same time each day to maintain consistent blood levels.\nAvoid abrupt discontinuation of the medication unless advised by your healthcare provider.\n\nSide Effects\nWhile CARDULES ISMN 10 is generally well-tolerated, some individuals may experience side effects, especially when starting treatment or adjusting dosage. Common and less serious side effects include:\n\nHeadache\n\nDizziness or light-headedness\n\nFlushing (warmth, redness, or tingly feeling under the skin)\n\nNausea\n\nFatigue\n\nIn rare cases, more serious side effects may occur, such as:\n\nSevere hypotension (low blood pressure)\n\nFainting\n\nIrregular heartbeat\n\nAllergic reactions like rash, itching, or swelling\n\nIf any severe or unusual side effects occur, seek immediate medical attention. Regular monitoring and dose adjustments may help manage and minimize side effects.",
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"description": "CARDULES ISMN 20 is a trusted cardiovascular medication formulated with Isosorbide Mononitrate 20 mg, primarily used to prevent and manage angina pectoris (chest pain) due to coronary artery disease. This medicine belongs to the class of drugs known as nitrates, which work by relaxing and widening the blood vessels, improving blood flow to the heart, and reducing its workload. CARDULES ISMN 20 plays a critical role in preventing episodes of angina, enhancing patient quality of life, and lowering the risk of heart-related complications when taken as prescribed.\n\nKey Ingredient\nIsosorbide Mononitrate (20 mg): A long-acting nitrate compound that acts as a vasodilator to reduce myocardial oxygen demand and improve oxygen supply to the heart.\n\nKey Benefits\nPrevents Angina Attacks: Helps in reducing the frequency and severity of chest pain episodes.\n\nImproves Heart Efficiency: Enhances blood flow and reduces the workload on the heart, making it easier for the heart to pump effectively.\n\nReduces Risk of Hospitalization: Long-term use helps reduce emergency visits and admissions due to angina.\n\nPromotes Better Exercise Tolerance: Allows patients with stable angina to engage in physical activity with reduced risk of chest pain.\n\nLong-Acting Relief: Designed for prolonged action, providing extended protection throughout the day when taken regularly.\n\nHow Does It Work?\nIsosorbide Mononitrate, the active ingredient in CARDULES ISMN 20, is a vasodilator that works by releasing nitric oxide, a natural compound in the body that relaxes smooth muscles of the blood vessels. This relaxation causes the veins and arteries to widen, which reduces the pressure on the heart and lowers oxygen demand. It also improves blood flow to the heart muscle, thereby preventing angina attacks. Unlike short-acting nitrates, Isosorbide Mononitrate has a prolonged action, making it suitable for maintenance therapy in chronic angina.\n\nDirections for Use\nTake CARDULES ISMN 20 exactly as prescribed by your physician.\n\nUsually taken once or twice daily, preferably in the morning and afternoon.\n\nSwallow the tablet whole with water; do not crush or chew.\n\nTake the medication on an empty stomach or after a light meal.\n\nMaintain consistent timing every day to achieve the best therapeutic effect.\n\nDo not stop suddenly without consulting your healthcare provider, as it may lead to worsening angina.\n\nImportant: Follow the nitrate-free interval as directed by your doctor to avoid nitrate tolerance (reduced effectiveness over time).\n\nSide Effects\nLike all medications, CARDULES ISMN 20 may cause side effects in some individuals. These are usually mild and temporary but should be monitored.\n\nCommon Side Effects:\n\nHeadache\n\nDizziness or lightheadedness (especially when standing up)\n\nFlushing or warmth in the face\n\nLow blood pressure\n\nNausea\n\nRare but Serious Side Effects:\n\nFainting\n\nIrregular heartbeat\n\nSevere hypotension\n\nAllergic reactions (rash, itching, swelling, especially of the face/tongue/throat)\n\nNote: If you experience severe or persistent side effects, seek medical attention promptly.\n\nPrecautions:\n\nDo not use CARDULES ISMN 20 with phosphodiesterase inhibitors (e.g., sildenafil) as it may cause dangerously low blood pressure.\n\nInform your doctor if you have a history of heart failure, hypotension, anemia, or liver disease.\n\nAvoid alcohol while taking this medicine as it may enhance the blood pressure-lowering effects.\n\nNot recommended for children or pregnant women unless advised by a healthcare professional.\n\nCARDULES ISMN 20 is a clinically proven and effective option for the long-term management of angina pectoris. Regular and proper use can significantly reduce chest pain episodes and improve your heart health and quality of life.",
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"description": "CARDULES ISMN SR 50 is a sustained-release tablet formulated with Isosorbide Mononitrate (50 mg), a nitrate-class medication widely used for the prevention and long-term management of angina pectoris (chest pain caused by heart disease). This medicine works by relaxing and widening the blood vessels, ensuring an adequate oxygen supply to the heart muscles and reducing the workload on the heart. It is primarily prescribed to individuals suffering from coronary artery disease or chronic stable angina.\n\n\nKey Benefits:\n\n\nPrevents angina attacks by increasing oxygen delivery to the heart muscles.\n\nImproves blood circulation by dilating the blood vessels, especially in the heart.\n\nReduces the workload on the heart, making it easier for patients with heart conditions to engage in daily activities.\n\nSustained-release formulation provides longer-lasting relief and maintains consistent therapeutic levels in the bloodstream.\n\nHelps manage chronic chest pain and enhances the overall quality of life in patients with heart-related conditions.\n\n\nHow Does It Work?\n\n\nIsosorbide Mononitrate, the active component in CARDULES ISMN SR 50, is a nitrate that undergoes biotransformation to release nitric oxide (NO), a natural vasodilator. Nitric oxide activates guanylate cyclase, leading to the production of cyclic GMP, which relaxes the smooth muscles of the blood vessels. This action reduces preload and afterload, lowering the heart's oxygen demand and preventing anginal episodes. The sustained-release mechanism ensures a steady release of the drug over time, providing prolonged therapeutic effects and reducing the frequency of dosing.\n\n\nDirections for Use:\n\n\nCARDULES ISMN SR 50 should be taken once daily, preferably in the morning after a light meal.\n\nSwallow the tablet whole with a glass of water. Do not crush or chew.\n\nFollow your healthcare provider's instructions regarding dosage and duration.\n\nAvoid abrupt discontinuation without consulting your doctor.\n\nMaintain a nitrate-free interval of 10-- 12 hours daily (as advised) to prevent tolerance buildup.\n\n\nSide Effects:\n\n\nWhile CARDULES ISMN SR 50 is generally well-tolerated, some individuals may experience:\n\nHeadache-- Common and usually resolves with continued use.\n\nDizziness or lightheadedness-- Especially when getting up from a sitting or lying position.\n\nFlushing or warmth in the face\n\nLow blood pressure (hypotension).\n\nNausea or vomiting.\n\nFatigue or weakness.\n\nSeek immediate medical attention if you experience severe allergic reactions, chest pain that worsens, or signs of low blood pressure such as fainting or vision changes.",
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"description": "TRIMETAZ CR 80 \nTrimetazidine (80mg)\nIntroduction\nTRIMETAZ CR 80 is a medication containing Trimetazidine hydrochloride, formulated to treat angina pectoris and certain other cardiovascular conditions. It is known for its metabolic effects on the heart muscle, improving myocardial efficiency and reducing symptoms associated with ischemic heart disease.\n\nComposition\n\nTrimetazidine (80mg): The active ingredient, Trimetazidine, acts as a cellular metabolic agent that enhances myocardial glucose utilization and improves energy production in the heart muscle.\nMechanism of Action\nTrimetazidine exerts its therapeutic effects through several mechanisms:\n\nMetabolic Regulation: Shifts myocardial energy substrate utilization from fatty acids toward glucose oxidation, which is more efficient and requires less oxygen.\nAnti-ischemic Effect: Protects the heart against ischemic damage by preserving cellular energy metabolism and reducing oxidative stress.\nImprovement in Symptomatology: Reduces angina symptoms such as chest pain, shortness of breath, and exercise intolerance by enhancing myocardial function.\nIndications\nTRIMETAZ CR 80 is indicated for:\n\nChronic Stable Angina Pectoris: Used as adjunctive therapy in patients who are inadequately controlled with other anti-anginal medications.\nIschemic Heart Disease: Helps improve myocardial function and reduce symptoms associated with coronary artery disease.\nDosage and Administration\n\nThe usual dosage of TRIMETAZ CR 80 is one tablet (80mg) taken orally twice daily, preferably with meals.\nThe extended-release formulation ensures sustained therapeutic levels of Trimetazidine throughout the day.\nDosage adjustments may be necessary based on individual patient response and tolerance.\nSide Effects\nCommon side effects may include:\n\nHeadache\nDizziness\nNausea\nGastrointestinal disturbances (such as abdominal pain or diarrhea)\nSevere side effects are rare but may include:\n\nAllergic reactions (rash, itching, swelling)\nExtrapyramidal symptoms (involuntary movements)\nHepatic dysfunction (monitor liver function tests periodically)\nPrecautions\n\nUse with caution in patients with severe renal impairment or hepatic dysfunction, as Trimetazidine metabolism may be altered.\nMonitor patients for signs of extrapyramidal symptoms, especially in patients with Parkinson's disease or other movement disorders.\nAvoid abrupt discontinuation of Trimetazidine, as it may worsen angina symptoms.\nDrug Interactions\n\nTrimetazidine may interact with other medications that affect myocardial metabolism or cardiac function, including beta-blockers and calcium channel blockers. Close monitoring is recommended when used concomitantly.\nConclusion\nTRIMETAZ CR 80 is a valuable therapeutic option for managing chronic stable angina pectoris and ischemic heart disease by improving myocardial efficiency and reducing symptoms associated with cardiac ischemia. Its mechanism of action, focusing on metabolic modulation and anti-ischemic effects, makes it an effective adjunctive therapy in patients with inadequate symptom control on standard anti-anginal medications. Proper dosage, administration, and monitoring for side effects are essential to ensure safe and effective use of TRIMETAZ CR 80 in cardiovascular patients. Consultation with a healthcare provider is recommended for personalized treatment plans and management of cardiac conditions with TRIMETAZ CR 80.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order NOW\n\n",
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