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{ "products": [ { "_id": "6abe4471401ae1a1106d67d9", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Bisoprolol 1.25mg", "description": "Bisoprolol 1.25mg is the smallest tablet strength of bisoprolol, a heart-selective beta-1 blocker. Doctors usually prescribe it to start treatment or to build up the dose gradually in people with high blood pressure, chronic stable heart failure, or fast heart rhythms. It suits older adults, people with mild heart failure, and anyone who reacts strongly to beta-blockers. The medicine slows the heartbeat and eases the force of each contraction, so the heart works less hard. BISOGARD 1.25 from Steris Healthcare Pvt. Ltd. comes in a strip pack of 15 tablets. It is a Schedule H medicine, so it must only be started, changed, or stopped on a doctor's advice.\n\nProduct Snapshot\n\nBrand: BISOGARD 1.25\nManufacturer/Marketer: Steris Healthcare Pvt. Ltd., a WHO-GMP and ISO-certified pharmaceutical company in India\nActive ingredient: Bisoprolol Fumarate 1.25mg\nForm: Tablet\nPack size: 15 tablets\nDrug class: Cardioselective beta-1 blocker\nLegal status: Schedule H (valid prescription required)\nAvailability: Through Steris Healthcare's authorized pharmacies and its B2B PCD franchise network across India\nWhat Is Bisoprolol 1.25mg?\n\nIf your doctor has just prescribed bisoprolol 1.25mg, you have been given the lowest dose on purpose. Bisoprolol is a cardioselective beta-1 blocker, meaning it acts mostly on receptors in the heart and has much less effect on the lungs and blood vessels. This is a major reason it is preferred over older, non-selective beta-blockers, especially for people who also have a mild breathing problem.\n\nThe 1.25mg tablet is not a “light” medicine for mild illness. It is a carefully chosen entry point. In heart failure, a weakened heart can struggle if its rate or pressure drops too quickly, so cardiologists follow a “start low, go slow” approach. Treatment begins at 1.25mg, the response is watched for one to two weeks, and the dose is raised step by step (commonly 2.5mg, 3.75mg, 5mg, 7.5mg, and up to 10mg) as the heart adapts. That is why BISOGARD 1.25 is often the first tablet a newly diagnosed heart failure patient takes.\n\nWhat Is Bisoprolol 1.25mg Used For?\n\nDoctors commonly prescribe this strength for:\n\nChronic heart failure (HFrEF): as the first step of dose titration in patients with a reduced ejection fraction, alongside ACE inhibitors/ARBs and diuretics\nHigh blood pressure: especially in older adults, people with low body weight, and those who are sensitive to blood-pressure-lowering drugs\nStable angina: to reduce the heart's oxygen demand and relieve chest discomfort\nAfter a heart attack: in selected patients, under a cardiologist's care\nHeart rate control in some arrhythmias: sometimes used off-label at a low dose to gently bring down a fast heart rate\n\nAt 1.25mg, bisoprolol is seldom meant as the long-term sole treatment for high blood pressure in an otherwise healthy adult. It is usually the first rung of a titration ladder, or a steady maintenance dose for patients who are unusually beta-blocker sensitive (older age, low body weight, or borderline low pressure or pulse).\n\nHow Does Bisoprolol Work?\n\nBisoprolol selectively blocks beta-1 adrenergic receptors, which are packed mainly into heart muscle. This leads to several effects:\n\nSlower heart rate: the heart has more time to fill and rest between beats\nGentler contractions: the heart muscle needs less oxygen and energy\nLess renin from the kidneys: this helps blood pressure fall gradually over time\nLower overall cardiac workload: a real advantage for a heart that already struggles to pump well, as in heart failure\nKey Benefits of BISOGARD 1.25\nA gentle starting dose, well suited to careful titration in frail or elderly patients\nHeart-focused action, with less effect on the lungs and peripheral blood vessels than non-selective beta-blockers\nOnce-daily dosing, which makes it easier to stay on treatment\nA guideline-recommended beta-blocker for HFrEF with well-established outcomes data [Reviewer note: insert specific outcome statistics/trial citation pending medical sign-off]\nMade by Steris Healthcare Pvt. Ltd. under WHO-GMP and ISO-certified standards\nDosage Guidance\nUsual starting dose (heart failure): 1.25mg once a day, preferably in the morning\nDose increases: typically every 1–2 weeks (2.5mg, 3.75mg, 5mg, 7.5mg, up to a maximum of 10mg daily), depending on how well you tolerate it and on your pulse and blood pressure\nHigh blood pressure (sensitive patients): 1.25mg to 5mg once daily, as set by your doctor\nHow to take it: at the same time every day, with or without food, swallowed whole with water\nIf you miss a dose: take it when you remember, unless the next dose is almost due. Never take a double dose.\nNever stop suddenly: abrupt withdrawal can cause a rebound rise in heart rate, blood pressure, or chest pain. The dose must be reduced gradually under medical supervision.\nIs It Better to Take Bisoprolol in the Morning or at Night?\n\nMost doctors advise a morning dose. Bisoprolol lowers pulse and blood pressure, and taking it early matches its action to your daytime activity. A night-time dose could add to the body's natural overnight dip in blood pressure and raise the chance of dizziness when getting up in the dark. Some people who feel tired during the day are told by their doctor to switch to the evening. Do not change your dosing time without your doctor's approval.\n\nSide Effects of Bisoprolol 1.25mg\n\nCommon side effects\n\nTiredness or fatigue\nDizziness or light-headedness, especially on standing quickly\nCold hands or feet\nSlow pulse (bradycardia)\nHeadache\nMild stomach upset (nausea, loose stools)\nDisturbed sleep\n\nSerious side effects (get medical help promptly)\n\nVery slow heartbeat or fainting\nIncreasing breathlessness or swollen legs/ankles, which may mean heart failure is worsening\nAllergic reaction: rash, swelling of the face or throat, trouble breathing\nCold, numb, or bluish fingers and toes\nWheezing or new breathing difficulty, particularly in people with asthma or COPD\nMood changes, low mood, or confusion\nWhat Are the Bad Side Effects of Bisoprolol?\n\nThe effects that need urgent attention are a dangerously slow pulse, fainting, signs of worsening heart failure (swelling, breathlessness), severe allergic reactions, and airway tightening in people with lung disease. These are uncommon at the 1.25mg dose, but anyone who notices them should seek medical help right away. [Reviewer note: specific incidence rates pending clinical/medical sign-off]\n\nSubstitutes & Comparable Beta-Blockers\nMolecule\tSelectivity\tTypical Use Case\nBisoprolol\tHighly cardioselective\tHeart failure titration, hypertension\nMetoprolol Succinate ER\tCardioselective\tHypertension, angina, heart failure\nAtenolol\tCardioselective (older agent)\tHypertension\nCarvedilol\tNon-selective with alpha-blocking action\tHeart failure (adds vasodilation)\nPropranolol\tNon-selective\tMigraine prevention, anxiety-related fast heartbeat, essential tremor\nPrecautions & Who Should Avoid Bisoprolol\nNot suitable for people with severe bradycardia, certain forms of heart block (unless a pacemaker is fitted), unstable or acutely decompensated heart failure, or severe uncontrolled asthma\nUse carefully in diabetes, because beta-blockers can hide the warning signs of low blood sugar\nTake care in peripheral vascular disease, as cold extremities or leg pain on walking may worsen\nNever stop it abruptly; always taper under a doctor's guidance\nTell your doctor about every medicine you use, especially other blood-pressure drugs, calcium channel blockers, and certain antiarrhythmics\nIn pregnancy and breastfeeding, use only if your doctor advises it after weighing benefits and risks\nIs Bisoprolol Safe for Kidneys?\n\nThe body clears bisoprolol through both the liver and the kidneys in roughly equal measure. It is generally considered safe for people with normal or mildly reduced kidney function. When kidney impairment is significant, drug levels in the blood can rise, so your doctor may lower the dose or monitor you more closely. Always tell your prescriber about any kidney disease before starting.\n\nIs Bisoprolol a High-Risk Medication?\n\nBisoprolol is not a narrow therapeutic index drug like tacrolimus or warfarin, where small dose differences matter greatly. Even so, it needs supervised use because it directly affects heart rate and blood pressure. The main dangers are stopping it suddenly, which can set off rebound cardiac events, and using it with certain existing rhythm disorders. Taken as prescribed and checked regularly, it has a long and reassuring safety record.\n\nDoes 1.25mg Bisoprolol Lower Blood Pressure?\n\nYes. Even the smallest dose measurably reduces heart rate and blood pressure by lightening the heart's workload and reducing renin-driven narrowing of blood vessels. At this strength the effect on blood pressure is fairly mild, which is exactly why it is a safe place to begin, especially for older adults or people starting heart failure treatment. The dose is then raised gradually to reach full benefit.\n\nFrequently Asked Questions\n\n1. What is 1.25 mg of bisoprolol used for?\nMainly as a low starting dose when building up treatment for chronic heart failure, and for high blood pressure in people who are very sensitive to beta-blockers, such as older adults.\n\n2. What are the bad side effects of bisoprolol?\nThe more serious ones are a very slow pulse, fainting, worsening heart failure signs (swelling, breathlessness), severe allergy, and breathing trouble in people with lung conditions.\n\n3. What are the common side effects of bisoprolol fumarate 1.25 mg tablets?\nTiredness, dizziness, cold hands and feet, mild headache, and a slightly slower pulse.\n\n4. Is it better to take bisoprolol in the morning or at night?\nMorning is usually preferred so its effect fits daytime activity, though your doctor may suggest evenings in some cases.\n\n5. What is the cost of bisoprolol?\nPrice depends on strength, pack size, and brand. Use the “Check Price” option above for current BISOGARD 1.25 pricing from Steris Healthcare.\n\n6. Does 1.25 mg bisoprolol lower blood pressure?\nYes, though only modestly at this dose. The dose is often stepped up over time.\n\n7. Is bisoprolol safe for kidneys?\nGenerally yes for normal or mildly reduced kidney function. People with significant kidney impairment need dose adjustment and monitoring.\n\n8. Is bisoprolol a high-risk medication?\nIt is not a narrow therapeutic index drug, but it must never be stopped suddenly and should be used under medical supervision because of its direct effect on the heart.\n\n9. Can I take bisoprolol 1.25mg for the rest of my life?\nMany people with chronic heart failure or hypertension do take bisoprolol long term, but the dose usually rises as tolerated. Your doctor should review it regularly.\n\n10. What happens if I miss a dose of bisoprolol?\nTake it when you remember, unless the next dose is nearly due. In that case skip the missed one. Never take two together.\n\n11. Can bisoprolol 1.25mg cause weight gain?\nIt is not commonly reported at this dose. Fluid retention linked to heart failure itself should be reported to your doctor.\n\n12. Is bisoprolol safe for diabetic patients?\nIt can be used, with care, because beta-blockers may hide warning signs of low blood sugar such as a racing heartbeat.\n\n13. Can I stop taking bisoprolol suddenly if I feel fine?\nNo. Stopping abruptly can cause a rebound rise in heart rate, blood pressure, or chest pain. Reduce the dose gradually under medical guidance.\n\n14. Does bisoprolol interact with other blood pressure medicines?\nYes. Combining it with other drugs that lower heart rate or pressure (such as calcium channel blockers) can cause a very low pulse or pressure. Tell your doctor about all your medicines.\n\n15. Is BISOGARD 1.25 available without a prescription?\nNo. Bisoprolol is a Schedule H medicine in India and needs a valid prescription.\n\n16. How long does it take for bisoprolol 1.25mg to start working?\nSome effect on heart rate appears within hours, but the full benefit for blood pressure or heart failure symptoms builds over several weeks of regular use.\n\n17. Can pregnant women take bisoprolol?\nOnly if clearly necessary and prescribed by a doctor, as it may affect the baby's heart rate and growth.", "price": 39.0, "discountamount": 12.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2501, "imageuri": "https://productimages.withfloats.com/actual/6abe4474c205678e0b16a23a.png", "tileimageuri": "https://productimages.withfloats.com/tile/6abe4474c205678e0b16a23a.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-10-01T11:30:57.88Z", "updatedon": "2026-10-01T11:30:57.88Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/bisoprolol-1-25mg/2501", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Bisogard 1.25", "category": "CARDIOLOGYRANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69f1cca37360b3ebd4a13fc4", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Cilostazol 100mg", "description": "If you are searching for an effective treatment to improve blood circulation and manage symptoms of peripheral vascular conditions, CILOSITAZON 100 (Cilostazol 100 mg) is a well-recognized and trusted option. This comprehensive, SEO-friendly guide is designed to help buyers and patients understand everything about this medication—its uses, benefits, dosage, safety profile, and why it is commonly prescribed.\n\nWhat is CILOSITAZON 100 (Cilostazol 100 mg)?\n\nCILOSITAZON 100 contains Cilostazol 100 mg, a medication classified as a phosphodiesterase III inhibitor. It works by widening blood vessels and preventing platelets from sticking together, thereby improving blood flow.\n\nThis medicine is primarily used in the treatment of intermittent claudication, a condition caused by reduced blood flow to the legs, which leads to pain while walking or exercising.\n\nHow Does Cilostazol 100 mg Work?\n\nCilostazol works through a dual mechanism:\n\nVasodilation: It relaxes blood vessels, allowing better blood flow to the limbs\nAntiplatelet Action: It reduces the clumping of platelets, preventing clot formation\n\nBy improving circulation, CILOSITAZON 100 helps patients walk longer distances without pain and enhances overall mobility.\n\nUses of CILOSITAZON 100\n1. Treatment of Intermittent Claudication\n\nThe primary use of Cilostazol is to relieve leg pain caused by poor circulation, especially in patients with peripheral artery disease (PAD).\n\n2. Improvement in Walking Distance\n\nIt significantly improves walking capacity and reduces discomfort during physical activity.\n\n3. Peripheral Vascular Disease (PVD)\n\nHelps manage symptoms associated with reduced blood supply to the extremities.\n\n4. Blood Circulation Support\n\nEnhances overall blood flow, making it beneficial for patients with vascular complications.\n\nKey Benefits of CILOSITAZON 100\n✔ Improved Blood Flow\n\nCilostazol widens blood vessels, ensuring better oxygen and nutrient delivery to tissues.\n\n✔ Increased Mobility\n\nPatients experience reduced pain while walking, allowing for improved daily activity.\n\n✔ Anti-Clotting Effect\n\nPrevents platelet aggregation, lowering the risk of clot-related complications.\n\n✔ Non-Surgical Option\n\nProvides a medical alternative to invasive treatments for circulation disorders.\n\n✔ Better Quality of Life\n\nRegular use can significantly enhance physical performance and comfort.\n\nDosage and Administration\nRecommended Dosage:\nTypically 100 mg twice daily or as prescribed by a healthcare professional\nHow to Take:\nTake on an empty stomach (at least 30 minutes before or 2 hours after meals)\nSwallow the tablet whole with water\nImportant Instructions:\nFollow your doctor’s advice strictly\nDo not skip doses\nDo not exceed the prescribed amount\nSide Effects of CILOSITAZON 100\n\nLike all medications, CILOSITAZON 100 may cause side effects in some individuals.\n\nCommon Side Effects:\nHeadache\nDiarrhea\nDizziness\nPalpitations\nLess Common but Serious Side Effects:\nRapid or irregular heartbeat\nSevere bleeding\nChest pain\nSwelling of the legs\n\nIf any serious symptoms occur, immediate medical attention is required.\n\nPrecautions and Warnings\n⚠️ Heart Conditions\n\nCilostazol is not recommended for patients with heart failure.\n\n⚠️ Bleeding Disorders\n\nUse with caution in individuals with a history of bleeding problems.\n\n⚠️ Pregnancy & Breastfeeding\n\nConsult your doctor before use.\n\n⚠️ Drug Interactions\n\nAvoid combining with:\n\nBlood thinners\nCertain antibiotics\nAntifungal medications\n\nAlways inform your healthcare provider about all medicines you are taking.\n\nStorage Instructions\nStore in a cool, dry place\nKeep away from direct sunlight\nKeep out of reach of children\nWho Should Consider CILOSITAZON 100?\n\nThis medication is suitable for individuals who:\n\nExperience leg pain while walking due to poor circulation\nAre diagnosed with peripheral artery disease\nNeed improved blood flow without surgical intervention\n\nHowever, it should always be used under proper medical supervision.\n\nBuying Guide for CILOSITAZON 100\n\nWhen purchasing CILOSITAZON 100, keep the following in mind:\n\n✔ Choose a Reliable Supplier\n\nBuy only from licensed pharmacies or trusted healthcare providers.\n\n✔ Check Product Authenticity\n\nVerify packaging, batch number, and expiry date.\n\n✔ Prescription Requirement\n\nEnsure you have a valid prescription from a doctor.\n\n✔ Compare Pricing\n\nEvaluate different brands for quality and affordability.\n\nWhy Choose CILOSITAZON 100?\n\nCILOSITAZON 100 (Cilostazol 100 mg) stands out due to its\n\nProven effectiveness in improving circulation\nDual action mechanism (vasodilation + antiplatelet)\nAbility to enhance walking distance and reduce pain\nNon-invasive treatment approach\n\nIt is widely recommended by healthcare professionals for managing peripheral vascular conditions effectively.\n\nConclusion\n\nCILOSITAZON 100 (Cilostazol 100 mg) is a highly effective medication designed to improve blood circulation and relieve symptoms of intermittent claudication. With its unique dual mechanism, it not only enhances blood flow but also reduces the risk of clot formation, making it a valuable option for patients with peripheral artery disease.", "price": 179.0, "discountamount": 54.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2392, "imageuri": "https://productimages.withfloats.com/actual/69f1cca6893ab121f53d8a91.png", "tileimageuri": "https://productimages.withfloats.com/tile/69f1cca6893ab121f53d8a91.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-04-29T09:17:23.076Z", "updatedon": "2026-04-30T09:01:52.993Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//cilostazol-100mg/2392", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CILOSITAZON 100", "category": "CARDIOLOGYRANGE", "tags": [ "cilostazol 100mg", "cilostazol 100mg tab", "tab cilostazol 100mg", "cilostazol 100mg tablets", "cilostazol 100mg price", "cilostazol 100mg uses", "tab. cilostazol 100mg", "cilostazol 100mg tablet" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69e9ed91fa23eada60366b93", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "nebivolol 2.5mg and cilnidipine 10 mg", "description": "If you are searching for an effective and well-balanced treatment for high blood pressure (hypertension), the combination of nebivolol 2.5mg and cilnidipine 10 mg is a modern and highly recommended therapy. This dual-action medication is designed to not only control blood pressure but also protect your heart and blood vessels over the long term.\n\nIn this buyer-focused guide, you will learn everything about nebivolol 2.5 mg and cilnidipine 10 mg, including how it works, benefits, dosage, safety, side effects, and what to consider before purchasing.\n\nWhat is Nebivolol 2.5mg and Cilnidipine 10 mg?\n\nNebivolol 2.5mg and cilnidipine 10 mg is a combination medicine used to treat hypertension. It combines two powerful agents:\n\nNebivolol (2.5mg): A beta-blocker that reduces heart rate and relaxes blood vessels\nCilnidipine (10mg): A calcium channel blocker that widens blood vessels and improves circulation\n\nTogether, these components work synergistically to provide effective and sustained blood pressure control.\n\nHow Does Nebivolol 2.5mg and Cilnidipine 10 mg Work?\n\nThis combination targets blood pressure through two complementary mechanisms, making it more effective than single-drug therapy.\n\nMechanism of Action\n1. Nebivolol Action\nBlocks beta-1 adrenergic receptors in the heart\nReduces heart rate and cardiac output\nPromotes release of nitric oxide, improving blood vessel dilation\n2. Cilnidipine Action\nBlocks L-type and N-type calcium channels\nRelaxes blood vessels and reduces resistance\nDecreases stress on blood vessel walls\nCombined Effect\nLowers blood pressure effectively\nImproves blood flow\nReduces strain on the heart\nHelps prevent complications like stroke and heart attack\nKey Benefits of Nebivolol 2.5mg and Cilnidipine 10 mg\n1. Dual Mechanism for Better Control\n\nTargets both heart rate and blood vessel resistance for optimal results.\n\n2. Effective Blood Pressure Reduction\n\nHelps maintain stable blood pressure levels throughout the day.\n\n3. Heart Protection\n\nReduces risk of cardiovascular complications.\n\n4. Improved Tolerability\n\nCombination therapy often leads to fewer side effects compared to higher doses of single drugs.\n\n5. Kidney Protection\n\nCilnidipine helps reduce protein loss in urine, supporting kidney health.\n\nWho Should Consider Buying This Medication?\n\nYou may consider nebivolol 2.5 mg and cilnidipine 10 mg if you:\n\nHave high blood pressure not controlled by a single medicine\nNeed a combination therapy for better results\nAre at risk of heart disease or stroke\nRequire long-term hypertension management\n\nImportant: This medication should only be used under a doctor’s prescription.\n\nDosage and Administration\nRecommended Dosage\nUsually one tablet once daily, or as prescribed\nCan be taken with or without food\nTake at the same time each day for consistency\nUsage Tips\nSwallow the tablet whole with water\nDo not skip doses\nDo not stop suddenly without consulting your doctor\nPossible Side Effects\n\nWhile this combination is generally well tolerated, some side effects may occur.\n\nCommon Side Effects\nHeadache\nDizziness\nFatigue\nSwelling in ankles (edema)\nSlow heart rate\n\nThese are usually mild and temporary.\n\nSerious Side Effects (Rare)\nSevere low blood pressure\nBreathing difficulty\nIrregular heartbeat\nSevere swelling\nAllergic reactions\n\nSeek immediate medical help if you experience serious symptoms.\n\nSafety Precautions Before Buying\nMedical Conditions\n\nInform your doctor if you have:\n\nHeart conditions (e.g., heart block, severe bradycardia)\nLiver or kidney disease\nAsthma or respiratory issues\nDiabetes\nPregnancy & Breastfeeding\nUse only if prescribed\nConsult your doctor before use\nDrug Interactions\n\nThis medication may interact with:\n\nOther blood pressure medicines\nHeart medications\nAntidiabetic drugs\nAlcohol (may increase dizziness)\nWhy Choose Combination Therapy?\n\nCombination medicines like nebivolol 2.5mg and cilnidipine 10 mg are increasingly preferred because they:\n\nProvide better blood pressure control\nReduce the need for multiple medications\nImprove patient compliance\nLower risk of side effects compared to high-dose monotherapy\nPrice in India\n\nThe price of nebivolol 2.5mg and cilnidipine 10 mg tablets in India depends on:\n\nBrand and manufacturer\nPackaging size\nPharmacy location\n\nAlways purchase from a trusted pharmacy or authorized distributor to ensure authenticity.\n\nStorage Instructions\nStore in a cool, dry place\nKeep away from direct sunlight\nKeep out of reach of children\nDo not use expired medicine\nFrequently Asked Questions (FAQs)\n1. What is nebivolol 2.5mg and cilnidipine 10 mg used for?\n\nIt is used to treat high blood pressure and reduce the risk of heart-related complications.\n\n2. Can I take this medicine daily?\n\nYes, but only as prescribed by your doctor.\n\n3. How long does it take to work?\n\nBlood pressure reduction may begin within a few days, with full effects in a few weeks.\n\n4. Is this combination safe?\n\nYes, when used under medical supervision.\n\n5. Can I stop taking it if I feel better?\n\nNo, stopping suddenly may cause blood pressure to rise again.\n\n6. Does it cause swelling?\n\nCilnidipine may cause mild ankle swelling in some patients.\n\nFinal Buying Advice\n\nIf you are looking for a reliable and advanced solution for hypertension, nebivolol 2.5mg and cilnidipine 10 mg is an excellent choice. Before purchasing:\n\nConsult your doctor\nCheck for genuine packaging\nFollow the prescribed dosage\nMonitor your blood pressure regularly\nConclusion\n\nNebivolol 2.5mg and cilnidipine 10 mg is a highly effective combination therapy designed to provide comprehensive blood pressure control while protecting your heart and blood vessels. With its dual mechanism, improved tolerability, and long-term benefits, it is a preferred option for many patients managing hypertension.", "price": 255.0, "discountamount": 76.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2388, "imageuri": "https://productimages.withfloats.com/actual/69e9ed93b34b94774f69ec0b.jpg", "tileimageuri": "https://productimages.withfloats.com/tile/69e9ed93b34b94774f69ec0b.jpg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-04-23T09:59:45.387Z", "updatedon": "2026-04-23T12:38:30.323Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//nebivolol-2-5mg-and-cilnidipine-10-mg/2388", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "NEBIVALVE CILNI 2.5/10", "category": "CARDIOLOGYRANGE", "tags": [ "tab nebivolol 2.5mg", "nebivolol 2.5mg", "nebivolol 2.5mg price", "nebivolol 2.5mg tablet", "tablet nebivolol 2.5mg", "nebivolol 2.5mg and cilnidipine 10 mg", "nebivolol 2.5mg uses", "nebivolol 2.5 mg cilnidipine 10 mg combination benefits", "what is nebivolol 2.5 mg and cilnidipine 10 mg used for", "nebivolol cilnidipine tablets price", "nebivolol 2.5 mg cilnidipine 10 mg supplier india", "nebivolol cilnidipine 2.5/10 tablet brand name", "nebivolol cilnidipine bulk manufacturer", "best price nebivolol cilnidipine tablets", "top quality nebivolol cilnidipine tablets" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69bd056b4b50865defcef3f2", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "olmesartan amlodipine hctz", "description": "Hypertension (high blood pressure) is one of the most widespread chronic health conditions today, often referred to as a “silent killer” because it can progress without noticeable symptoms. If left unmanaged, it significantly increases the risk of heart attack, stroke, kidney failure, and other life-threatening complications. For patients with moderate to severe or resistant hypertension, single-drug therapy may not be sufficient to achieve optimal control.\n\nTRIOLMISTRUM 40 is an advanced triple-combination medication containing Olmesartan Medoxomil, Amlodipine, and Hydrochlorothiazide (HCTZ). This powerful formulation is designed to provide comprehensive blood pressure management through three complementary mechanisms, ensuring better control, improved patient outcomes, and long-term cardiovascular protection.\n\nComposition\n\nOlmesartan Medoxomil (40 mg)\n\nAmlodipine (5 mg or as prescribed)\n\nHydrochlorothiazide (12.5 mg or as prescribed)\n\nThis triple combination targets different pathways involved in blood pressure regulation, making it highly effective for patients who require intensive treatment.\n\nHow TRIOLMISTRUM 40 Works\n1. Olmesartan Medoxomil Mechanism\n\nOlmesartan is an Angiotensin II Receptor Blocker (ARB) that:\n\nBlocks the action of angiotensin II, a hormone that narrows blood vessels\n\nRelaxes and widens arteries\n\nReduces blood pressure and improves blood flow\n\nProtects organs such as the heart and kidneys\n\n2. Amlodipine Mechanism\n\nAmlodipine is a calcium channel blocker that:\n\nPrevents calcium from entering the muscle cells of blood vessels\n\nCauses vasodilation (widening of blood vessels)\n\nImproves circulation and reduces resistance in arteries\n\n3. Hydrochlorothiazide (HCTZ) Mechanism\n\nHydrochlorothiazide is a thiazide diuretic that:\n\nHelps eliminate excess salt and water from the body through urine\n\nReduces blood volume\n\nLowers blood pressure and decreases swelling\n\nCombined Effect\n\nThe three drugs work together to:\n\nProvide superior blood pressure control\n\nReduce fluid overload\n\nImprove vascular relaxation\n\nMinimize the risk of cardiovascular complications\n\nUses of TRIOLMISTRUM 40\n1. Treatment of Hypertension\n\nEffective for moderate to severe high blood pressure\n\nSuitable for patients requiring triple therapy\n\n2. Resistant Hypertension\n\nIdeal for individuals whose BP remains uncontrolled with two medications\n\n3. Prevention of Cardiovascular Events\n\nReduces the risk of heart attack, stroke, and heart failure\n\n4. Fluid Retention Management\n\nHelps reduce edema associated with hypertension\n\nKey Benefits of TRIOLMISTRUM 40\n1. Triple Action Formula\n\nCombines three different classes of antihypertensive drugs for maximum effectiveness.\n\n2. Superior Blood Pressure Control\n\nProvides consistent, 24-hour BP reduction\n\nReduces morning BP surges\n\n3. Reduced Risk of Complications\n\nProtects against heart disease and stroke\n\nHelps maintain kidney health\n\n4. Improved Patient Compliance\n\nSingle-tablet therapy reduces pill burden\n\nEasy once-daily dosing\n\n5. Effective in Resistant Cases\n\nWorks well when dual therapy fails\n\n6. Controls Fluid Balance\n\nHCTZ reduces excess fluid and swelling\n\n7. Enhances Overall Cardiovascular Health\n\nImproves blood vessel function\n\nReduces strain on the heart\n\nDosage and Administration\n\nTake TRIOLMISTRUM 40 exactly as prescribed by your doctor\n\nUsually taken once daily, preferably at the same time each day\n\nCan be taken with or without food\n\nAvoid missing doses for consistent BP control\n\nSide Effects of TRIOLMISTRUM 40\n\nLike all medications, TRIOLMISTRUM 40 may cause some side effects.\n\nCommon Side Effects\n\nDizziness\n\nHeadache\n\nFatigue\n\nSwelling of ankles (due to Amlodipine)\n\nIncreased urination\n\nLess Common Side Effects\n\nLow blood pressure (hypotension)\n\nElectrolyte imbalance (low potassium or sodium)\n\nNausea\n\nMuscle cramps\n\nSerious Side Effects (Rare)\n\nSevere dehydration\n\nKidney function changes\n\nIrregular heartbeat\n\nAllergic reactions (rash, itching, swelling)\n\nSeek immediate medical help if serious side effects occur.\n\nPrecautions and Warnings\n\nPregnancy: Not recommended as it may harm the fetus\n\nBreastfeeding: Consult a doctor before use\n\nKidney or Liver Disease: Use with caution\n\nElectrolyte Monitoring: Regular blood tests may be required\n\nAlcohol Consumption: May increase dizziness and risk of low BP\n\nDrug Interactions: Inform your doctor about all medications being taken\n\nWho Should Use TRIOLMISTRUM 40?\n\nThis medication is suitable for:\n\nPatients with uncontrolled or severe hypertension\n\nIndividuals needing triple-drug therapy\n\nPatients at high cardiovascular risk\n\nThose experiencing fluid retention with high BP\n\nLifestyle Tips for Better Results\n\nTo maximize the benefits of TRIOLMISTRUM 40:\n\nFollow a low-salt diet\n\nExercise regularly (at least 30 minutes daily)\n\nMaintain a healthy weight\n\nAvoid smoking and excessive alcohol\n\nPractice stress management techniques\n\nMonitor blood pressure regularly\n\nConclusion\n\nTRIOLMISTRUM 40 (Olmesartan, Amlodipine & Hydrochlorothiazide Tablets) represents a comprehensive and highly effective solution for managing hypertension, especially in patients requiring advanced therapy. Its triple-action formula addresses multiple pathways involved in blood pressure regulation, ensuring better control and long-term protection against cardiovascular complications.", "price": 135.0, "discountamount": 95.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2345, "imageuri": "https://productimages.withfloats.com/actual/69bd056e8a311bc9dd97e3e7.png", "tileimageuri": "https://productimages.withfloats.com/tile/69bd056e8a311bc9dd97e3e7.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-03-20T08:29:31.42Z", "updatedon": "2026-03-20T08:29:31.42Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//olmesartan-amlodipine-hctz/2345", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "TRIOLMISTRUM 40", "category": "CARDIOLOGYRANGE", "tags": [ "olmesartan amlodipine hctz", "olmesartan amlodipine hydrochlorothiazide combination benefits", "olmesartan amlodipine hctz dosage guide", "olmesartan amlodipine hctz tablets for hypertension", "olmesartan amlodipine hctz how it works", "best time to take olmesartan amlodipine hctz tablets", "olmesartan amlodipine hctz tablets review india", "olmesartan amlodipine hctz tablets for uncontrolled bp", "best medicine for high bp triple combination india", "olmesartan amlodipine hctz tablets for stage 2 hypertension", "triple therapy tablets for high blood pressure india", "what is olmesartan amlodipine hctz used for", "olmesartan amlodipine hctz morning or night", "olmesartan amlodipine hctz side effects in hindi", "buy olmesartan amlodipine hctz tablets online", "olmesartan amlodipine hctz tablets price in india", "lmesartan amlodipine hctz bulk supplier india", "best olmesartan amlodipine hctz brand in india", "olmesartan amlodipine hctz vs telmisartan combination" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6958dbfa1063d98b1e8f2fe1", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Benidipine 4mg", "description": "BENIPRIME 4, containing Benidipine 4 mg, offers effective management for high blood pressure and related heart conditions. This calcium channel blocker helps relax blood vessels to improve blood flow and reduce strain on the heart. Patients often find it reliable for daily control of hypertension symptoms.\n\nWhat is BENIPRIME 4?\nBENIPRIME 4 is a branded tablet from Steris Healthcare Pvt Ltd, featuring 4 mg of Benidipine as the active ingredient. Benidipine belongs to the dihydropyridine class of calcium channel blockers, designed specifically for cardiovascular health. Each tablet delivers a precise dose in a user-friendly form, typically packaged in strips of 10 for convenient use. Manufactured under strict quality standards, it targets essential needs in hypertension care, making it a staple in many treatment plans across India.\n​\n\nThis medication stands out due to its triple action on L-type, N-type, and T-type calcium channels, providing broader vascular protection compared to some other blockers. Doctors prescribe it for adults dealing with persistent high blood pressure or chest pain, often starting at this 4 mg strength for balanced efficacy. Unlike generic options, BENIPRIME 4 ensures consistent absorption and formulation tailored for Indian patients, with pricing around Rs 62-89 per strip after discounts.\n​\n\nHow BENIPRIME 4 Works\nBenidipine in BENIPRIME 4 blocks calcium entry into smooth muscle cells of blood vessels and heart muscles. This action causes vasodilation, widening arteries to lower resistance and ease blood flow. By reducing systolic and diastolic pressure, it lightens the heart's workload without drastically slowing the heartbeat.\n​\n\nThe unique blockade of multiple calcium channels also boosts nitric oxide production, offering antioxidant effects and protection against artery hardening. This sustained mechanism provides 24-hour control, ideal for once-daily dosing after breakfast. Over time, it may even reduce urinary protein and triglycerides, supporting kidney and metabolic health in hypertensives.\n​\n\nKey Uses of BENIPRIME 4\nBENIPRIME 4 primarily treats essential hypertension, helping prevent strokes, heart attacks, and kidney damage. It effectively manages angina pectoris by enhancing coronary blood supply, reducing chest pain episodes during activity.\n​\n\nPhysicians also use it for renal parenchymal hypertension, where kidney issues elevate blood pressure. In emergencies like hypertensive crises or subarachnoid hemorrhage, higher doses prove beneficial, though 4mg serves as maintenance. For arrhythmia or anal fissures linked to vascular strain, it offers supportive relief.\n​\n\nLowers high blood pressure in adults, including severe cases with dose adjustments.\n​\n\nEases angina symptoms, improving exercise tolerance and daily life quality.\n​\n\nProtects renal function in proteinuric patients by stabilizing vessels.\n​\n\nDosage and Administration\nTake BENIPRIME 4 as 4 mg once daily, swallowed whole after a meal to minimize stomach upset. Doctors may adjust to 2-8mg based on response, age, or kidney/liver status, never exceeding 8 mg daily without monitoring. Consistency in timing ensures steady levels for optimal pressure control.\n​\n\nMissed doses require prompt intake if remembered soon, but skip if near the next one—avoid doubles. Pair with lifestyle changes like low-salt diets and exercise for best results. Always consult for personalization, especially in elderly or comorbid patients.\n​\n\nKey Benefits\nBENIPRIME 4 excels in long-term blood pressure reduction, with studies showing sustained drops in brachial-ankle pulse wave velocity beyond mere pressure effects. It protects the heart and kidneys through anti-sclerotic and antioxidant actions, lowering cardiovascular event risks.\n​\n\nPatients experience fewer angina attacks, better endurance, and improved quality of life. The once-daily regimen boosts adherence, while vascular selectivity minimizes reflex tachycardia common in other blockers. Clinical data indicate reduced C-reactive protein and aldosterone, curbing inflammation and fibrosis.\n​\n\nBenefit\tDescription\tSupporting Evidence\nBP Control\tReduces systolic/diastolic pressure effectively over 24 hours \n​\tLong-term studies show persistent effects post-treatment \n​\nHeart Protection\tImproves coronary flow, cuts angina frequency \n​\tMyocardial protection via NO stimulation \n​\nRenal Support\tLowers proteinuria, aids kidney hypertension \n​\tAnti-oxidative vascular benefits \n​\nAdherence Ease\tOnce-daily dosing with sustained release \n​\tHigh membrane affinity for lasting action \n​\nAdditional perks include potential triglyceride reduction and osteoblast stimulation for bone health in hypertensives.\n\nPotential Side Effects\nMost users tolerate BENIPRIME 4 well, with mild, transient effects resolving spontaneously. Common issues include headache, dizziness, flushing, ankle swelling, palpitations, fatigue, nausea, and sleepiness.\n​\n\nLess frequent are constipation, abdominal pain, tinnitus, shoulder stiffness, urinary frequency, or elevated liver enzymes. Rare serious reactions involve severe hypotension, rash, itching, or allergic responses—seek immediate care if these arise. Monitor blood pressure during initiation to avoid drops.\n\nHeart-related: Palpitations, chest pressure\n​\n\nNervous system: Dizziness, headache\n\nSkin/Vascular: Flushing, edema.\n\nGI: Nausea, constipation\n​\n\nLiver/kidney patients need caution; inform doctors of history.\n\n\nPrecautions and Interactions\nAvoid in hypotension, severe aortic stenosis, or hypersensitivity to dihydropyridines. Use cautiously in liver/kidney impairment, pregnancy, or breastfeeding—benefits must outweigh risks. Grapefruit juice may amplify effects; limit alcohol.\n​\n\nIt interacts with beta-blockers, digoxin, or CYP3A4 inhibitors like ketoconazole, potentially enhancing hypotension. Regular monitoring of BP, electrolytes, and renal function is advised during therapy. Abrupt stop may rebound pressure; taper under guidance.\n​\nConclusion\nBENIPRIME 4 with Benidipine 4 mg empowers reliable hypertension and angina control through innovative calcium channel action. Balancing potent benefits like organ protection and ease of use against manageable side effects, it fits seamlessly into modern cardiac care. Consult healthcare providers for tailored integration with lifestyle for lasting heart health. ", "price": 89.0, "discountamount": 27.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2261, "imageuri": "https://productimages.withfloats.com/actual/6958dbfc615a7d157715572f.jpg", "tileimageuri": "https://productimages.withfloats.com/tile/6958dbfc615a7d157715572f.jpg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-03T09:06:02.841Z", "updatedon": "2026-03-13T06:54:02.808Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//benidipine-4mg/2261", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "BENIPRIME 4", "category": "CARDIOLOGYRANGE", "tags": [ "benidipine 4mg", "benidipine 4mg tab", "benidipine hydrochloride uses.", "benidipine.", "benidipine 4 mg", "benidipine 4", "benidipine maximum dose", "benidipine 4 mg uses.", "benidipine price" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "693c0f0df827a9801a26dcd7", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Isosorbide mononitrate IP 60mg Tablets", "description": "CARDULES ISMN SR 60 delivers Isosorbide Mononitrate IP 60mg in a sustained-release tablet form, designed for long-term prevention of angina in patients with coronary artery disease. Produced by Steris Healthcare Pvt Ltd, this formulation ensures steady drug release over 12-24 hours, optimizing cardiovascular protection with once-daily dosing convenience. It supports heart health by enhancing blood flow without the peaks and troughs of immediate-release options.​\n\nProduct Overview\nCARDULES ISMN SR 60 contains Isosorbide Mononitrate IP 60mg per sustained-release tablet, a pure nitrate metabolite that bypasses first-pass liver metabolism for consistent bioavailability. The SR technology employs a polymer matrix to gradually liberate the active ingredient, maintaining therapeutic plasma levels throughout the day and minimizing tolerance development associated with frequent dosing. Available in strips of 10 tablets, it features a film-coated exterior for easy swallowing and gastro-resistant properties to protect against stomach acid degradation.​\n\nThis higher 60mg strength suits patients requiring intensified prophylaxis after initial titration from lower doses like 30mg or 40mg. It integrates seamlessly into comprehensive cardiac regimens alongside beta-blockers, statins, or aspirin, under cardiologist supervision. Quality manufacturing adheres to IP standards, ensuring purity above 99% with low impurity profiles for safety in chronic use.​\n\nKey Uses\nCARDULES ISMN SR 60 primarily prevents chronic stable angina pectoris by dilating coronary arteries and reducing myocardial oxygen demand during exertion. Patients experience fewer episodes of chest tightness, pressure, or discomfort triggered by physical activity, stress, or cold exposure.​\n\nIt manages coronary artery disease (CAD) by improving collateral circulation and easing ischemia in narrowed vessels. Often prescribed post-angioplasty or alongside lifestyle modifications, it stabilizes symptoms for enhanced daily functioning.​\n\nAdditionally, it supports adjunctive therapy in congestive heart failure or post-myocardial infarction recovery, where vasodilation unloads the heart. Not for acute attacks—use sublingual nitroglycerin instead—but vital for long-term risk reduction.​\n\nMajor Benefits\nThe sustained-release profile of CARDULE ISMN SR 60 provides 24-hour angina prevention with single morning dosing, improving adherence over multiple-daily regimens. This steady vasodilation lowers preload via venous pooling and afterload via arterial relaxation, cutting oxygen consumption by up to 20-30% during stress.​\n\nPatients report increased exercise tolerance, with treadmill tests showing delayed onset of ST-segment depression. Enhanced myocardial perfusion boosts energy levels, enabling a return to work, hobbies, or family activities without fear of sudden symptoms.​\n\nCompared to shorter-acting nitrates, tolerance buildup is slower due to a nitrate-free interval built into once-daily use. Cost-effective at higher strengths, it reduces overall healthcare visits and hospitalization risks from unstable angina.​\n\nBenefit\tMechanism\tClinical Advantage\nAngina Prevention\tVasodilation reduces preload/afterload. ​\tFewer episodes, better quality of life\nExercise Capacity\tImproved coronary flow ​\tExtended activity duration by 50%+\nDosing Simplicity\tSR once daily ​\t90% adherence rate vs. multiple doses\nHeart Protection\tLowers ischemia risk. ​\tReduced MI recurrence\nPotential Side Effects\nCommon effects include headache (orthostatic or throbbing), especially in the first week, resolving with hydration and dose acclimation—acetaminophen helps manage it. Dizziness, lightheadedness, or postural hypotension may occur; rise slowly from sitting.​\n\nGastrointestinal upset like nausea or flushing affects 5-10% initially. Avoid alcohol or PDE5 inhibitors (e.g., sildenafil) to prevent severe hypotension.​\n\nRarely, reflex tachycardia, rash, or methemoglobinemia arises; monitor liver enzymes in prolonged use. Contraindicated in severe anemia, glaucoma, or recent PDE5 intake—discontinue if allergic reactions appear.​\n\nDosage Guidelines\nInitiate at 30-40mg daily, titrating to 60mg once in the morning on an empty stomach for optimal absorption. Swallow whole; do not crush. A 10-12 hour nitrate-free window (nighttime) prevents tolerance.​\n\nAdjust for renal/hepatic impairment; max 120mg/day. Store below 25°C. Regular ECG and BP checks ensure efficacy.​\nConclusion\nCARDULES ISMN SR 60 stands as a cornerstone in angina prophylaxis, empowering CAD patients with reliable, sustained vascular relief from Steris Healthcare. Consistent use alongside diet, exercise, and smoking cessation maximizes outcomes, but cardiologist oversight remains essential for safety", "price": 155.0, "discountamount": 47.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2244, "imageuri": "https://productimages.withfloats.com/actual/693c0f14d878634fd7a965ca.png", "tileimageuri": "https://productimages.withfloats.com/tile/693c0f14d878634fd7a965ca.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-12T12:48:13.762Z", "updatedon": "2026-03-14T08:23:14.824Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//isosorbide-mononitrate-ip-60mg-tablets/2244", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CARDULES ISMN SR 60", "category": "cardiology", "tags": [ "Isosorbide mononitrate IP 60mg Tablets", "coronary artery disease", "supports heart health by enhancing blood flow", "gastro-resistant properties to protect against stomach acid", "Contraindicated in severe anemia, glaucoma, or recent PDE5", "coronary artery disease.", "It supports heart health by enhancing blood.", "isosorbide mononitrate 60mg.", "isosorbide 60mg.", "isosorbide mononitrate.", "isosorbide dinitrate tablet uses in hindi", "isosorbide", "isosorbide mononitrate uses", "isosorbide mononitrate 30 mg", "isosorbide mononitrate tablet uses in hindi" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "693c0c9c0c30ac5c9f8203b4", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Isosorbide Mononitrate IP 30mg Tablets", "description": "CARDULES ISMN SR 30 tablets provide sustained-release Isosorbide Mononitrate IP 30mg, a nitrate medication designed for long-term management of angina in patients with coronary artery disease. This formulation from Steris Healthcare Pvt Ltd ensures steady vasodilation to improve heart blood flow and reduce chest pain episodes. It supports daily activities by minimizing oxygen demand on the heart muscle.​\nProduct Overview\nCARDULES ISMN SR 30 contains Isosorbide Mononitrate IP 30mg in a sustained-release matrix, allowing once-daily dosing for consistent therapeutic levels over 12-24 hours. The tablet's extended-release technology prevents peak-trough fluctuations common in immediate-release forms, promoting better patient compliance. Each film-coated tablet delivers precise bioavailability, with the active metabolite nitric oxide activating guanylate cyclase to boost cyclic GMP, relaxing vascular smooth muscle primarily in veins.​\n\nThis mechanism reduces preload (venous return to the heart) and afterload (arterial resistance), easing cardiac workload without significantly affecting heart rate. Unlike short-acting nitrates for acute relief, CARDULES ISMN SR 30 targets prophylaxis in chronic stable angina, often prescribed alongside beta-blockers or calcium channel blockers. Available in strips of 10 tablets, it undergoes rigorous quality testing at Steris facilities to meet IP standards, ensuring purity and stability.​\n\nKey Uses\nCARDULES ISMN SR 30 primarily prevents angina pectoris in coronary artery disease, where narrowed vessels limit oxygen supply during exertion. Patients experience fewer chest pain attacks during walking, climbing stairs, or stress.​\n\nIt manages chronic stable angina by enhancing myocardial perfusion, suitable for long-term therapy in adults over 18. Healthcare providers may use it adjunctively for coronary spasm or post-myocardial infarction prophylaxis to stabilize symptoms.​\n\nIn select cases, it aids heart failure management by offloading the heart, though not as monotherapy. Always initiate under cardiology supervision with dose titration to tolerance.​\n\nMajor Benefits\nThe sustained-release profile offers 24-hour protection with single morning dosing, improving adherence and lifestyle quality for active patients. It boosts exercise tolerance by 20-30% in trials, allowing longer physical efforts without angina onset.​\n\nBy dilating vessels, it decreases ischemia risk, potentially lowering hospitalization rates for acute episodes. Compared to placebo, users report halved attack frequency within weeks, enhancing daily productivity and emotional well-being.​\n\nBenefit\tMechanism\tPatient Outcome\nAngina Prevention\tVasodilation reduces preload/afterload ​\tFewer attacks, better exertion capacity\nSteady Relief\tSR formulation maintains levels ​\tOnce-daily convenience, no fluctuations\nHeart Protection\tImproves O2 delivery ​\tReduced ischemia, enhanced QoL\nCompliance Boost\tSimple regimen ​\tHigher adherence vs multiple doses\nAdditional perks include minimal impact on blood pressure in normotensives and compatibility with anti-anginals, making it versatile in combo therapy.\n\nPotential Side Effects\nCommon effects include headache (dose-related, often transient in first week), dizziness, or flushing due to vasodilation—hydrate and rise slowly to manage. Gastrointestinal upset like nausea occurs in 5-10% initially.​\n\nOrthostatic hypotension risks fainting, especially early; avoid alcohol or other vasodilators. Rare serious issues encompass severe hypotension, tachycardia, or methemoglobinemia with overdose—monitor blood pressure regularly.​\n\nAllergic reactions (rash, itching) or vision changes warrant discontinuation. Contraindicated in hypotension, glaucoma, or recent PDE5 inhibitor use; caution in anemia or hypothyroidism.​\n\nDosage Guidelines\nStart with 30mg once daily upon waking, swallowed whole without crushing. Titrate to 60mg if tolerated after 3-7 days, max 120mg/day. Take on empty stomach for optimal absorption; avoid late dosing to prevent nocturnal headaches.​\n\nAdjust for elderly or renal/hepatic impairment. Tolerance may develop—nitrate-free interval (evening) helps sustain efficacy. Store below 30°C.​\nConclusion\nCARDULES ISMN SR 30 empowers angina patients with reliable, once-daily prevention, restoring confidence in routine activities under Steris Healthcare's quality assurance. Its targeted vasodilation balances efficacy and tolerability for sustained heart health", "price": 65.0, "discountamount": 19.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2243, "imageuri": "https://productimages.withfloats.com/actual/693c0ca6391a3fa44b0608d8.png", "tileimageuri": "https://productimages.withfloats.com/tile/693c0ca6391a3fa44b0608d8.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-12T12:37:48.92Z", "updatedon": "2026-03-14T08:21:58.091Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//isosorbide-mononitrate-ip-30mg-tablets/2243", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CARDULES ISMN SR 30", "category": "", "tags": [ "Isosorbide Mononitrate IP 30mg Tablets", "coronary artery disease", "heart blood flow and reduce chest pain episodes", "oxygen demand on the heart muscle", "relaxing vascular smooth muscle primarily in veins" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6926f07d1a6e5ed700f07efd", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Ambrisentan 5mg, Tadalafil 20mg", "description": "Ambrisentan + Tadalafil (5 mg + 20mg) is a combination medication primarily used to treat pulmonary arterial hypertension (PAH), a condition characterized by high blood pressure in the arteries of the lungs. This combination works through a synergistic dual mechanism of action to improve pulmonary vascular health and reduce the strain on the heart.\n\nAmbrisentan acts as an endothelin receptor antagonist, selectively blocking endothelin type A receptors. Endothelin is a naturally occurring substance that causes blood vessels to constrict, increasing blood pressure. By blocking these receptors, ambrisentan helps to relax and widen the pulmonary arteries, reducing vascular resistance and improving blood flow. Tadalafil, on the other hand, is a phosphodiesterase type 5 (PDE5) inhibitor that increases cyclic guanosine monophosphate (cGMP) levels, leading to vasodilation and enhanced blood flow. Together, these two drugs complement each other by reducing vessel constriction and promoting dilation, effectively lowering pulmonary arterial pressure and helping the right side of the heart pump more efficiently.​\n\nThe key benefits of the Ambrisentan + Tadalafil combination include improved exercise capacity, better heart function, and reduced symptoms of PAH such as shortness of breath and fatigue. Clinical studies have demonstrated that this combination significantly improves hemodynamics—the dynamics of blood flow—by reducing pulmonary vascular resistance and improving right ventricular (RV) function and structure. It also helps enhance patients' quality of life by increasing their ability to perform physical activities.​\n\nWhile the combination is generally well tolerated, some side effects may occur. Common side effects include headache, nasal congestion, flushing, and swelling of the ankles or legs, which are typical of vasodilator therapies. Some patients may experience gastrointestinal symptoms such as nausea or indigestion. Less commonly, serious side effects such as liver enzyme elevation, hypotension (low blood pressure), or allergic reactions may occur. Patients should consult healthcare professionals before using this combination, especially those with low blood pressure, liver issues, or those taking nitrates due to potential interactions.​\n\nIn conclusion, Ambrisentan + Tadalafil (5mg + 20mg) provides an effective treatment option for patients with pulmonary arterial hypertension by combining two complementary mechanisms to relax and dilate pulmonary arteries, decrease vascular resistance, and improve heart function and exercise tolerance. Patients are advised to use this medication under medical supervision to ensure safety and monitor for possible side effects. This combination therapy represents a significant advancement in managing PAH and improving patient outcomes.​\nThis product is an important therapeutic option and should be integrated into a comprehensive PAH management plan that includes lifestyle modifications, regular monitoring, and adherence to prescribed treatment.", "price": 1800.0, "discountamount": 951.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2220, "imageuri": "https://productimages.withfloats.com/actual/6926f08fce3236cca23d19b7.jpeg", "tileimageuri": "https://productimages.withfloats.com/tile/6926f08fce3236cca23d19b7.jpeg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-26T12:20:13.462Z", "updatedon": "2026-03-14T08:20:11.529Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//ambrisentan-5mg-tadalafil-20mg/2220", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "AMBRISTAR 5 + DURA 20 ", "category": "cardiology", "tags": [ "Ambrisentan + Tadalafil (5 mg + 20mg)", "ambrisentan + tadalafil.", "increasing blood pressure.", "ambrisentan + tadalafil.", "ambrisentan + tadalafil combination.", "high blood pressure in the arteries of the lungs.", "ambrisentan tadalafil combination.", "ambrisentan tadalafil.", "tab ambrisentan tadalafil.", "ambrisentan tadalafil price.", "ambrisentan tadalafil uses in hindi.", "ambrisentan tadalafil fixed dose combination." ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69142bf71d499513a92e5772", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Nicorandil Tablets 5mg", "description": "Nicorandil Tablets 5 mg is a vasodilatory anti-anginal medication widely prescribed for the management and prevention of angina pectoris (chest pain) associated with coronary artery disease (CAD). Angina results from an imbalance between the heart’s oxygen demand and supply due to restricted blood flow in the coronary arteries. Nicorandil offers a dual mechanism of action — acting both as a nitrate-like vasodilator and a potassium channel opener, making it unique among anti-anginal agents.\n\nBy improving oxygen delivery to the myocardium and reducing cardiac workload, Nicorandil 5 mg Tablets provide effective relief from anginal pain and reduce the frequency and severity of ischemic episodes. It is also beneficial in preventing future attacks, improving exercise tolerance, and enhancing the overall quality of life in patients with chronic stable angina.\n\nComposition\n\nEach tablet contains:\n\nNicorandil IP – 5 mg\n\nExcipients – q.s.\n\nNicorandil tablets are available in film-coated form to ensure stability, easy swallowing, and optimal absorption. They are manufactured in compliance with Good Manufacturing Practices (GMP) standards to ensure safety, purity, and efficacy.\n\nPharmacological Action / Mechanism of Action\n\nNicorandil exhibits a dual mechanism that makes it distinct among anti-anginal drugs:\n\nNitrate-Like Effect:\nNicorandil acts as a nitric oxide (NO) donor. Nitric oxide activates guanylate cyclase, increasing cyclic GMP (cGMP) levels in vascular smooth muscle. This leads to relaxation of blood vessels, particularly veins and large arteries, thereby reducing preload and afterload on the heart. This nitrate-like activity lowers myocardial oxygen demand.\n\nPotassium Channel Opening Effect:\nNicorandil opens ATP-sensitive potassium (KATP) channels in vascular smooth muscle, resulting in arteriolar vasodilation. This increases coronary blood flow and improves oxygen supply to ischemic heart tissues.\n\nTogether, these effects reduce cardiac workload, enhance coronary perfusion, and prevent anginal pain by correcting the oxygen supply-demand mismatch in the heart muscle.\n\nUses and Indications\n\nNicorandil Tablets 5 mg are indicated for the treatment and prevention of angina pectoris in adults, particularly:\n\nChronic Stable Angina:\n\nHelps reduce the frequency and severity of chest pain associated with exertion or emotional stress.\n\nProphylaxis of Angina Attacks:\n\nUsed regularly to prevent anginal episodes, especially in patients with known coronary artery disease.\n\nAdjunct Therapy in Ischemic Heart Disease (IHD):\n\nCan be used alongside beta-blockers, calcium channel blockers, or antiplatelet drugs for enhanced symptom control and long-term protection.\n\nImprovement of Exercise Tolerance:\n\nReduces the likelihood of anginal pain during physical activity, enabling patients to perform daily tasks comfortably.\n\nIn some clinical cases, Nicorandil is also considered for post-myocardial infarction recovery, as it improves coronary perfusion, although this is at the discretion of a cardiologist.\n\nDosage and Administration\n\nRecommended Starting Dose: 5 mg to 10 mg twice daily.\n\nMaintenance Dose: May be increased gradually to 10–20 mg twice daily, depending on clinical response and tolerance.\n\nThe tablets should be swallowed whole with water, preferably at the same times each day.\n\nNicorandil should not be stopped abruptly; dosage tapering is recommended to avoid rebound angina.\n\nAlways follow the dosage instructions provided by the physician.\n\nKey Benefits\n\nDual Mechanism for Comprehensive Relief:\nCombines nitrate-like and potassium channel-opening properties for both arterial and venous dilation, providing superior protection against anginal attacks.\n\nImproves Coronary Blood Flow:\nDilates coronary arteries, increasing oxygen delivery to ischemic myocardial tissues.\n\nReduces Cardiac Workload:\nBy decreasing preload (venous return) and afterload (arterial resistance), Nicorandil minimizes the heart’s oxygen consumption.\n\nRapid Onset of Action:\nNicorandil acts within a short duration, offering quick relief from anginal discomfort.\n\nPrevents Future Angina Episodes:\nRegular use helps maintain steady control of chest pain, improving exercise capacity and quality of life.\n\nCompatible with Other Cardiac Medications:\nCan be safely used alongside antiplatelet agents, beta-blockers, ACE inhibitors, and statins as part of comprehensive cardiac care.\n\nFavorable Safety Profile:\nCompared to nitrates, Nicorandil carries a lower risk of tolerance development, making it suitable for long-term therapy.\n\nEnhances Myocardial Protection:\nNicorandil’s KATP channel activation provides additional cardioprotective effects by improving microvascular blood flow and limiting ischemic damage during stress.\n\nPrecautions and Warnings\n\nAlthough Nicorandil is generally well-tolerated, certain precautions are advised:\n\nHypotension:\nNicorandil may cause a drop in blood pressure due to vasodilation. Caution is advised in patients with hypotension or dehydration.\n\nConcurrent Use with Nitrates:\nShould not be used together with other nitrate medications to avoid severe hypotension.\n\nOral or Gastrointestinal Ulcers:\nRarely, Nicorandil may cause ulcerations in the mouth, intestines, or skin. Treatment should be discontinued if ulceration occurs.\n\nPatients with Low Blood Volume:\nUse cautiously in individuals with hypovolemia or those on diuretics.\n\nDriving and Machinery:\nDizziness or light-headedness may occur; avoid driving until effects are known.\n\nPregnancy and Lactation:\nShould be used only if prescribed by a physician when the potential benefits outweigh the risks.\n\nPossible Side Effects\n\nNicorandil is generally safe but may cause some side effects, particularly at the start of therapy or with higher doses. Common and rare adverse reactions include:\n\nCommon Side Effects:\n\nHeadache (due to vasodilation)\n\nFlushing or warmth sensation\n\nDizziness or light-headedness\n\nNausea or mild stomach upset\n\nFatigue or weakness\n\nLess Common / Rare Side Effects:\n\nHypotension (low blood pressure)\n\nPalpitations or tachycardia\n\nMouth ulcers, anal ulcers, or skin ulceration (uncommon but serious — discontinue if occurs)\n\nRash or allergic reaction\n\nVisual disturbances (rare and usually reversible)\n\nIf any severe reaction or persistent discomfort occurs, medical attention should be sought promptly.\n\nDrug Interactions\n\nAvoid concomitant use with nitrates or phosphodiesterase type-5 inhibitors (e.g., Sildenafil, Tadalafil), as it may cause a dangerous fall in blood pressure.\n\nCaution with antihypertensive drugs or diuretics, which may enhance hypotensive effects.\n\nAlcohol consumption can potentiate dizziness or hypotension and should be limited.\n\nStorage and Handling\n\nStore below 30°C, protected from moisture and direct sunlight.\n\nKeep out of reach of children.\n\nDo not use tablets past the expiry date or if the packaging is damaged.\n\nConclusion\n\nNicorandil Tablets 5 mg offer a modern and effective approach to managing angina pectoris, providing reliable relief through their dual-action mechanism. By combining nitrate-like vasodilation with potassium channel opening, Nicorandil ensures both oxygen supply improvement and reduction of cardiac workload — the cornerstone of angina management.\n\nIt is well-tolerated, fast-acting, and suitable for long-term therapy, making it a preferred choice for patients with chronic stable angina. Regular use under medical supervision helps reduce the frequency of chest pain, improve physical endurance, and enhance the overall quality of life in individuals with coronary artery disease.", "price": 381.0, "discountamount": 115.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2202, "imageuri": "https://productimages.withfloats.com/actual/69142c03b53db80943abd33d.png", "tileimageuri": "https://productimages.withfloats.com/tile/69142c03b53db80943abd33d.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-12T06:40:55.795Z", "updatedon": "2026-03-16T08:18:00.245Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//nicorandil-tablets-5mg/2202", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MAYORANDIL 5 ", "category": "CARDIOLOGYRANGE", "tags": [ "nicorandil tablets 5mg", "nicorandil 5 mg tablets uses", "nicorandil tablet 5mg benefits", "nicorandil 5mg medicine", "nicorandil tablets ip 5 mg", "what is nicorandil 5mg used for", "how does nicorandil tablet work", "nicorandil 5mg mechanism of action", "nicorandil tablets for angina treatment", "nicorandil tablet uses in heart disease", "nicorandil 5mg tablet price in india", "buy nicorandil 5mg tablets online", "nicorandil 5mg tablet brands", "nicorandil tablets manufacturer", "nicorandil tablets wholesale supplier" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false } ], "hasmoreitems": false, "isapirequest": false, "totalresults": 27, "query": null, "floatingpoint": null }