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"name": "Glimepiride IP1 mg, Voglibose IP 0.2 MG & Metformin Hydrochloride IP 500 mg ",
"description": "GLIMITERIS MV1 0.2 is an advanced fixed-dose combination (FDC) medication designed for adults with Type 2 Diabetes Mellitus (T2DM) who require more than lifestyle modifications or single/dual therapy to maintain optimal blood sugar levels. This innovative formulation brings together the power of three well-established antidiabetic agents—Glimepiride (1 mg), Voglibose (0.2 mg), and Metformin Hydrochloride SR (500 mg)—to provide comprehensive glycemic control.\n\nIt is particularly effective for patients struggling with postprandial hyperglycemia, fasting glucose regulation, and HbA1c reduction, making it a preferred choice in cases of poorly controlled diabetes.\n\n \n\nMechanism of Action\nThe therapeutic benefit of GLIMITERIS MV1 0.2 comes from the unique synergy of its three components, each targeting different aspects of glucose metabolism:\n\n1. Glimepiride (1 mg) – Sulfonylurea\nStimulates insulin secretion by activating pancreatic beta cells.\n\nProvides a long-lasting effect with comparatively lower hypoglycemia risk than older sulfonylureas.\n\nHelps reduce both fasting and postprandial glucose levels.\n\n2. Voglibose (0.2 mg) – Alpha-Glucosidase Inhibitor\nDelays the breakdown and absorption of carbohydrates in the intestine.\n\nMinimizes post-meal glucose spikes (PPBG).\n\nActs locally in the gut and has minimal systemic absorption, which reduces systemic side effects.\n\n3. Metformin Hydrochloride SR (500 mg) – Biguanide\nDecreases hepatic glucose production (gluconeogenesis).\n\nImproves peripheral insulin sensitivity, enhancing glucose uptake in muscles.\n\nDoes not cause hypoglycemia on its own.\n\nThe sustained-release (SR) formulation ensures extended control and reduces gastrointestinal side effects.\n\n \n\nIndications\nGLIMITERIS MV1 0.2 is indicated for:\n\nAdults with Type 2 Diabetes Mellitus.\n\nPatients inadequately controlled with monotherapy or dual therapy.\n\nManagement of fasting and postprandial hyperglycemia.\n\nLong-term HbA1c reduction as part of a comprehensive diabetes care plan.\n\n \n\nKey Benefits\n✅ Comprehensive Blood Sugar Control – Acts on fasting, post-meal, and long-term HbA1c levels.\n✅ Postprandial Spike Management – Voglibose effectively controls carbohydrate-induced sugar surges.\n✅ Reduced Pill Burden – Combines three medicines into a single tablet.\n✅ Lower Hypoglycemia Risk – Metformin and Voglibose balance out Glimepiride’s insulin-secreting effect.\n✅ Weight Management Support – Metformin may promote modest weight loss or prevent weight gain.\n✅ Improved Tolerability – SR formulation of Metformin enhances gastrointestinal comfort.\n\n \n\nDosage and Administration\nRecommended dose: One tablet once or twice daily with meals, or as directed by the physician.\n\nAdministration tips:\n\nTake with the first bite of a main meal to maximize Voglibose’s effect.\n\nSwallow whole with water; do not crush or chew the SR tablet.\n\nDose adjustments: Based on blood sugar monitoring, clinical response, and renal/hepatic function.\n\n \n\nContraindications\nGLIMITERIS MV1 0.2 is not suitable for patients with:\n\nType 1 diabetes or diabetic ketoacidosis.\n\nSevere renal impairment (eGFR <30 mL/min/1.73 m²).\n\nHepatic dysfunction.\n\nSevere gastrointestinal diseases.\n\nHistory of lactic acidosis.\n\nHypersensitivity to Glimepiride, Voglibose, or Metformin.\n\nPregnancy and lactation (unless strictly advised by a physician).\n\n \n\nWarnings and Precautions\nHypoglycemia: Risk is higher when combined with other antidiabetics or with missed meals.\n\nLactic Acidosis: A rare but life-threatening effect of Metformin—renal function monitoring is essential.\n\nGI Side Effects: Voglibose and Metformin may cause bloating, flatulence, or diarrhea (usually temporary).\n\nVitamin B12 Monitoring: Long-term Metformin use may reduce B12 absorption.\n\nLiver and Kidney Function: Regular monitoring is recommended for safe long-term use.\n\n \n\nAdverse Effects\nCommon:\nGlimepiride: Mild hypoglycemia, dizziness, slight weight gain.\n\nVoglibose: Gas, abdominal discomfort, mild diarrhea.\n\nMetformin SR: Nausea, bloating, metallic taste, loose stools.\n\nRare but Serious:\nLactic acidosis (from Metformin).\n\nSevere hypoglycemia (especially if meals are skipped).\n\nAllergic reactions such as rash, itching, or swelling.\n\nElevated liver enzymes.\n\nSeek medical attention if symptoms such as rapid breathing, confusion, severe fatigue, or muscle pain occur.\n\n \n\nDrug Interactions\nIncreased hypoglycemia risk: With insulin, beta-blockers, and sulfonylureas.\n\nReduced Metformin efficacy: With corticosteroids, estrogens, and diuretics.\n\nLactic acidosis risk: Higher with alcohol or iodinated contrast agents. ",
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"description": "CITICOTIME PM is a specialized formulation combining Citicoline 500mg and Piracetam 800mg in tablet form, designed to enhance brain health and cognitive functions. This combination harnesses the synergistic effects of two well-researched nootropic agents—citicoline and piracetam tablets—widely used in neurological therapies. Primarily, this medicine supports nerve cell nourishment, protects neurons from damage, and aids in improving memory, focus, and recovery in brain-related conditions such as stroke. Its unique formulation offers neuroprotection and cognitive enhancement, making it an important therapeutic option in treating stroke and other cognitive impairments.\n\nWhat is CITICOTIME PM?\nCITICOTIME PM contains a combination of two active ingredients: Citicoline 500mg, a neuroprotective compound that promotes brain cell repair and function, and Piracetam 800mg, which enhances neuronal communication and cognitive processes. Together, they work to support brain metabolism, improve blood flow, and strengthen cognitive resilience. This formulation is often prescribed to patients recovering from neurological injuries or those experiencing cognitive decline.\n\nUses of Citicoline and Piracetam Tablets\n\nTreatment and recovery support in stroke patients to restore brain function\n\nImprovement of memory, learning ability, and cognitive performance\n\nManagement of neurological disorders such as dementia and Alzheimer's disease\n\nNeuroprotection against brain cell damage caused by trauma or ischemia\n\nEnhancement of mental alertness and reduction of cognitive fatigue\n\nSupport in conditions involving cognitive impairment due to aging or injury\n\nCiticoline + Piracetam is used in the treatment of stroke. Citicoline + Piracetam is a combination of two medicines: Citicoline and Piracetam. Citicoline is a nerve protecting medicine. It works on the brain by nourishing the nerve cells, protects them from damage and improves their survival.\n\nCiticoline and Piracetam Tablets Dosage\nThe recommended dosage depends on the patient's condition, age, and response to therapy. Typically, CITICOTIME PM is taken once or twice daily as prescribed by a healthcare professional. Each tablet delivers Citicoline 500mg and Piracetam 800mg, providing an effective dose for neuroprotection and cognitive support. It should be swallowed whole with water, preferably after meals to reduce gastrointestinal discomfort. Dosage adjustments may be necessary in patients with kidney impairment or other comorbidities. It is critical to follow a doctor's prescribed dosage and not to self-medicate.\n\nSide Effects of Citicoline and Piracetam Tablets\nWhile generally well tolerated, some individuals may experience side effects, which are usually mild and temporary, including:\n\nHeadache\n\nNausea and stomach discomfort\n\nInsomnia or trouble sleeping\n\nNervousness or agitation\n\nDizziness and vertigo\n\nWeight gain in some cases\n\nRare allergic reactions such as skin rash or swelling\n\nChanges in blood pressure or heart rate (typically uncommon)\n\nIf severe side effects or allergic reactions occur, immediate medical attention is advised.\n\nPrecautions Before Using CITICOTIME PM\n\nConsult a doctor before use if you have a history of brain hemorrhage, bleeding disorders, or gastrointestinal ulcers.\n\nUse caution in elderly patients and those with renal or hepatic impairment.\n\nAvoid driving or operating heavy machinery until you know how the medicine affects you.\n\nDo not consume alcohol while taking this medication, as it may increase side effects like drowsiness or nervousness.\n\nInform your healthcare provider if you are pregnant, trying to conceive, or breastfeeding, as safety in these conditions is not fully established.\n\nDo not abruptly stop the medication without medical advice to avoid withdrawal symptoms such as muscle twitching.\n\nDrug Interactions: What Drugs Interact with CITICOTIME PM?\n\nAnticoagulants or blood thinners may increase the risk of bleeding.\n\nOther central nervous system (CNS) stimulants or depressants can enhance side effects like dizziness or drowsiness.\n\nMedications processed by kidneys require careful monitoring as both citicoline and piracetam are primarily excreted renally.\n\nAlcohol consumption can exacerbate side effects, especially sedation and nervousness.\n\nAlways inform your doctor about all medications and supplements you are taking to avoid harmful interactions.\n\nCITICOTIME PM, with citicoline 500mg and piracetam 800mg, is a reliable choice for managing stroke recovery and cognitive disorders by protecting and nourishing nerve cells, improving brain function, and supporting neuronal survival. Proper medical supervision is essential to maximize benefits and minimize risks associated with citicoline and piracetam tablets uses and dosage.",
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"description": "DULOXTIME M 20/750 is a powerful combination medication used primarily in the management of neuropathic pain, fibromyalgia, diabetic nerve pain, and certain mood-related conditions. With a dual-action formula combining Duloxetine and Methylcobalamin, this medicine helps in managing nerve-related discomfort while also supporting nerve regeneration and mental well-being. It is often prescribed in chronic conditions where nerve pain and vitamin B12 deficiency coexist.\n\nKey Ingredients\nDuloxetine 20mg\nDuloxetine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that works on the central nervous system to relieve pain and improve mood. It is widely used for treating anxiety, depression, and chronic pain syndromes, especially those linked to nerve damage.\n\nMethylcobalamin 750mcg\nMethylcobalamin is an active form of Vitamin B12, essential for nerve health and red blood cell formation. It plays a vital role in regenerating damaged nerves and reducing symptoms like tingling, numbness, and weakness in patients with neuropathy.\n\nKey Benefits\nProvides effective relief from neuropathic pain and nerve inflammation\n\nEnhances nerve regeneration and improves nerve function\n\nSupports mental well-being by treating mood disorders like depression and anxiety\n\nCorrects Vitamin B12 deficiency, which is common in patients with nerve-related issues\n\nHelps manage chronic conditions like diabetic neuropathy and fibromyalgia\n\nMay improve sleep quality and reduce fatigue associated with nerve pain\n\nHow Does It Work?\nDuloxetine functions by increasing the levels of serotonin and norepinephrine in the brain. These neurotransmitters play a key role in pain modulation and emotional stability. By restoring their balance, Duloxetine alleviates both physical pain and associated psychological symptoms.\n\nMethylcobalamin, on the other hand, repairs damaged neurons and supports the formation of the protective myelin sheath around nerves. It contributes to the regeneration of nerve cells and improves nerve signal transmission, leading to a significant reduction in nerve pain and discomfort.\n\nTogether, these two components provide a synergistic effect, addressing both the root cause and the symptoms of neuropathic disorders.\n\nDirections for Use\nTake DULOXTIME M 20/750 exactly as prescribed by your doctor\n\nUsually taken once or twice daily with or without food\n\nSwallow the tablet whole with a glass of water; do not crush or chew\n\nConsistency is important — take the medicine at the same time every day\n\nDo not abruptly stop taking the medication without medical advice, as it may cause withdrawal symptoms\n\nSide Effects\nLike all medicines, DULOXTIME M 20/750 may cause some side effects. These are usually mild and temporary, but medical attention may be required if they persist.\n\nNausea or vomiting\n\nDry mouth\n\nDrowsiness or fatigue\n\nDizziness or light-headedness\n\nIncreased sweating\n\nConstipation\n\nLoss of appetite\n\nHeadache\n\nInsomnia (trouble sleeping)\n\nBlurred vision\n\nWeight changes\n\nMood swings or irritability (in rare cases)\n\nAllergic reactions like rash or itching (in very rare cases)\n\nIf you experience symptoms like severe dizziness, shortness of breath, persistent vomiting, or swelling, seek immediate medical help.",
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"description": "GLIEMPAFLOZIN MET ER is a combination medication used to manage type 2 diabetes mellitus (T2DM) by helping control blood sugar levels effectively. It contains two powerful anti-diabetic agents, Empagliflozin and Metformin Hydrochloride (Extended Release), which work together to enhance glucose regulation and reduce the risk of diabetes-related complications. This medication is recommended for patients who require additional glycemic control beyond lifestyle changes and monotherapy treatments.\n\n \nKey Benefits\n \n\n Effective Blood Sugar Control – Helps reduce and maintain optimal blood glucose levels in type 2 diabetic patients.\nWeight Management – Empagliflozin promotes caloric loss through urinary glucose excretion, potentially aiding in weight reduction.\nReduced Risk of Cardiovascular Diseases – Beneficial for heart health, lowering the risk of cardiac complications in diabetic patients.\nInsulin Sensitivity Improvement – Metformin enhances insulin function, reducing insulin resistance.\nLower Risk of Hypoglycemia – A balanced mechanism of action ensures stable blood glucose levels without sudden drops.\nKidney Protection – Empagliflozin may help protect against diabetic nephropathy by reducing kidney stress.\nExtended-Release Formula – Ensures long-lasting blood sugar control with a once-daily dosage for improved patient compliance.\n \nHow Does It Work?\n \n\nEmpagliflozin (SGLT2 Inhibitor) – Blocks the SGLT2 protein in the kidneys, preventing glucose reabsorption and promoting its excretion through urine, thereby reducing blood sugar levels.\nMetformin Hydrochloride (Biguanide) – Reduces glucose production in the liver, enhances insulin response, and delays glucose absorption in the digestive tract.\nTogether, they provide a dual action approach for better glycemic control while minimizing side effects like hypoglycemia.\n \nDirections for Use\n \n\nDosage: Take one tablet per day, preferably with food or as directed by your healthcare provider.\nSwallow whole with a glass of water; do not crush or chew.\n Maintain a healthy diet and follow a regular exercise routine for optimal results.\nRegular monitoring of blood sugar levels is advised.\nDo not stop taking this medication without consulting your doctor.\n\n \nSide Effects:\n \n\nSome individuals may experience mild to moderate side effects, including:\n\nFrequent urination (due to glucose excretion)\nDehydration (increased fluid loss)\nNausea, vomiting, or stomach upset\nDiarrhea or constipation\nMetallic taste in the mouth\nLow blood pressure (Hypotension)\nVitamin B12 deficiency (with long-term use of Metformin)\nUrinary tract infections (UTIs) or genital infections\n Seek medical attention if you experience severe allergic reactions, extreme dizziness, or difficulty breathing.",
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