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"description": "GLICLAGLAZE MET \ngliclazide SR (60mg),Metformin SR (500 mg)\nIntroduction\nGLICLAGLAZE MET is an advanced formulation designed for the effective management of Type 2 diabetes. This oral medication combines sustained release (SR) forms of Gliclazide (60 mg) and Metformin (500 mg), offering controlled and consistent blood glucose control throughout the day.\n\nMechanism of Action\n\nGliclazide SR (60 mg): As a sulfonylurea drug, Gliclazide SR works by stimulating insulin secretion from the beta cells of the pancreas. The sustained release form provides a gradual increase in insulin levels, reducing the risk of sudden drops in blood sugar that can lead to hypoglycemia.\nMetformin SR (500 mg): Metformin SR decreases hepatic glucose production and increases insulin sensitivity in peripheral tissues, notably muscles. Its sustained release formulation ensures a steady effect on blood sugar levels, improving metabolic response without the peaks and troughs associated with immediate-release forms.\nBenefits\nGLICLAGLAZE MET is specifically tailored to provide a more stable and prolonged effect in controlling blood sugar, which can enhance patient compliance and comfort. The combination of Gliclazide SR and Metformin SR in one tablet simplifies the treatment regimen, potentially improving adherence and reducing the risk of missed doses.\n\nDosage and Administration\n\nDosage: The dosage of GLICLAGLAZE MET should be individualized based on the patient's current control and therapeutic response. It is crucial to monitor blood glucose regularly to adjust the dosage appropriately.\nAdministration: This medication should be taken with meals to minimize gastrointestinal side effects and improve the absorption of the drug.\nSide Effects\nWhile GLICLAGLAZE MET is generally well tolerated, some patients may experience side effects such as gastrointestinal discomfort, including nausea and diarrhea. The risk of hypoglycemia is present but is generally lower with the sustained release formulation.\n\nConclusion\nGLICLAGLAZE MET offers a balanced and effective approach to managing Type 2 diabetes by combining two proven diabetes medications in a sustained release form. This regimen not only aids in maintaining steady blood glucose levels but also supports overall diabetes management by enhancing patient adherence to treatment. Patients are encouraged to maintain a dialogue with their healthcare provider to optimize treatment outcomes and address any concerns during their treatment journey.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order Now\nhttps://www.sterisonline.com/product/gliclaglaze-met-133421\n\n\n\n\n\n",
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"description": "GLIPIDIAB 5 is an oral antidiabetic medication containing Glipizide 5 mg, which belongs to the class of drugs known as sulfonylureas. It is widely prescribed for individuals with Type 2 Diabetes Mellitus (T2DM) to help control blood sugar levels when diet and lifestyle measures alone are not sufficient. GLIPIDIAB 5 works by stimulating the pancreas to produce more insulin and enhancing the body’s ability to utilize that insulin effectively.\n\nAs Type 2 diabetes often progresses over time, the pancreas gradually produces less insulin. GLIPIDIAB 5 helps bridge that gap by promoting insulin secretion, thereby lowering elevated fasting and post-meal blood glucose levels. It is usually taken once daily before meals, although dosage and frequency vary depending on a doctor’s evaluation of the patient’s condition.\n\nGLIPIDIAB 5 is often used alone or in combination with other antidiabetic medications such as metformin, DPP-4 inhibitors, or insulin, depending on the severity of blood sugar imbalance. Its predictable glucose-lowering effect makes it a long-standing and reliable treatment option in diabetes care.\n\nUses of GLIPIDIAB 5\n\nGLIPIDIAB 5 is primarily used for:\n\n1. Management of Type 2 Diabetes Mellitus\n\nIts main role is to help lower high blood glucose levels in adults diagnosed with T2DM. By improving insulin secretion, it helps maintain smoother and more stable sugar control throughout the day.\n\n2. Prevention of Diabetes-Related Complications\n\nMaintaining blood sugar within the target range reduces the risk of long-term complications such as:\n\nNerve damage (neuropathy)\n\nKidney disease (nephropathy)\n\nEye problems (retinopathy)\n\nCardiovascular diseases\n\nPoor wound healing\n\n3. Supporting Comprehensive Diabetes Treatment Plans\n\nGLIPIDIAB 5 is often part of a broader diabetes management plan that includes diet adjustment, physical activity, and regular monitoring of glucose levels.\n\nKey Benefits of GLIPIDIAB 5\n1. Effective Blood Sugar Reduction\n\nGLIPIDIAB 5 works quickly and efficiently to reduce blood sugar by boosting insulin release, making it effective for controlling both fasting and meal-related spikes in glucose.\n\n2. Long-Established Safety and Reliability\n\nGlipizide has been used in diabetes treatment for decades, with well-understood actions and predictable results. Its long history makes it a trusted choice among healthcare professionals.\n\n3. Convenient Once-Daily Dosing\n\nMost patients take the medicine once daily before breakfast, making it simple and easy to incorporate into a daily routine.\n\n4. Can Be Combined with Other Antidiabetic Medicines\n\nGLIPIDIAB 5 works well with other medications, especially when blood sugar control requires a multi-drug approach.\n\n5. Helps Reduce Future Health Risks\n\nBy maintaining controlled sugar levels, GLIPIDIAB 5 contributes to reducing the risk of serious long-term diabetes complications and enhances overall quality of life.\n\nPossible Side Effects\n\nLike all medications, GLIPIDIAB 5 may cause side effects. These vary among individuals and may include:\n\nCommon Side Effects\n\nLow blood sugar (hypoglycemia) — symptoms include sweating, dizziness, hunger, trembling, or palpitations\n\nNausea or stomach discomfort\n\nHeadache\n\nMild skin reactions such as rash or itching\n\nLess Common but Serious Side Effects\n\nSevere hypoglycemia, especially if meals are skipped or excessive insulin is produced\n\nLiver-related issues (rare)\n\nAllergic reactions such as swelling or severe skin redness\n\nBlood disorders like anemia (rare)\n\nTo reduce the risk of low blood sugar, regular meals and proper monitoring are important.\n\nConclusion\n\nGLIPIDIAB 5 is a proven and effective medication for managing Type 2 diabetes, particularly in patients who need additional insulin stimulation to maintain normal blood sugar levels. By enhancing natural insulin production and helping prevent long-term diabetes complications, it plays a vital role in comprehensive diabetes care. While it offers significant benefits, it must be used responsibly under medical supervision, especially because of its potential to cause low blood sugar. With consistent use, lifestyle adjustments, and regular monitoring, GLIPIDIAB 5 can greatly contribute to stable glucose control and improved overall health for individuals living with Type 2 diabetes.",
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"description": "Sitagliptin 50 mg, Metformin Hydrochloride 1000 mg, and Glimepiride 2 mg is a triple-combination oral anti-diabetic medication formulated to achieve optimal blood sugar control in adults with Type 2 Diabetes Mellitus (T2DM). This unique blend brings together three complementary agents — Sitagliptin (a DPP-4 inhibitor), Metformin (a biguanide), and Glimepiride (a sulfonylurea) — that work through distinct mechanisms to enhance glucose regulation, improve insulin sensitivity, and support overall metabolic balance.\n\nThis advanced combination therapy is prescribed when monotherapy or dual therapy fails to achieve adequate glycemic control. It helps reduce both fasting plasma glucose (FPG) and postprandial glucose (PPG) levels, promoting stable long-term glycemic management.\n\nUses of Sitagliptin + Metformin + Glimepiride\n\nThis fixed-dose combination is primarily indicated for the management of Type 2 Diabetes Mellitus in adults. It is especially beneficial for patients whose blood sugar levels remain uncontrolled despite treatment with Metformin and Glimepiride or Metformin and Sitagliptin alone.\n\nIts main objectives include:\n\nControlling elevated blood glucose levels in adults with Type 2 diabetes\n\nReducing the risk of diabetes-related complications such as neuropathy, nephropathy, and cardiovascular diseases\n\nSupporting better insulin utilization by the body\n\nComplementing diet, exercise, and lifestyle modification to maintain optimal glycemic balance\n\nMechanism of Action\n\nEach component of this combination plays a vital role in maintaining blood sugar control:\n\nSitagliptin (50 mg) – A Dipeptidyl Peptidase-4 (DPP-4) inhibitor that enhances the activity of incretin hormones. 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It works synergistically with Metformin and Sitagliptin for more effective glycemic control.\n\nKey Benefits\n\nTriple Mechanism for Superior Control:\nBy combining three potent agents, the medication addresses multiple pathways of glucose regulation—insulin secretion, insulin sensitivity, and hepatic glucose output—resulting in comprehensive and consistent control of blood sugar levels.\n\nEffective Glycemic Stability:\nThe combination helps maintain target HbA1c levels and reduces both fasting and post-meal glucose spikes without significant weight gain when used with proper diet and exercise.\n\nReduced Risk of Diabetic Complications:\nLong-term blood sugar control minimizes the risk of complications such as kidney disease, vision problems, nerve damage, and heart conditions associated with uncontrolled diabetes.\n\nConvenient Fixed-Dose Formulation:\nCombining three medications into a single tablet simplifies dosing schedules, improves patient adherence, and reduces pill burden, which is crucial for long-term treatment success.\n\nImproved Insulin Efficiency:\nEnhances the body's natural insulin response and glucose metabolism, allowing for smoother daily energy levels and reduced fatigue associated with hyperglycemia.\n\nPossible Side Effects\n\nWhile this combination is generally well tolerated, some patients may experience side effects, especially at the beginning of therapy. Common and rare side effects include:\n\nHypoglycemia (low blood sugar): More likely when meals are skipped or during excessive physical exertion. Symptoms include sweating, dizziness, and rapid heartbeat.\n\nGastrointestinal disturbances: Such as nausea, vomiting, diarrhea, abdominal discomfort, or loss of appetite (mostly due to Metformin).\n\nHeadache or Weakness: Usually mild and transient.\n\nAllergic reactions: Rarely, rash or itching may occur.\n\nLactic Acidosis (rare but serious): A potential complication of Metformin, particularly in patients with kidney impairment or excessive alcohol consumption.\n\nWeight gain: Mild weight gain may occur due to Glimepiride’s insulin-enhancing effect.\n\nPrecautions:\n\nRegular monitoring of blood sugar levels and kidney function is essential.\n\nAvoid alcohol and consult a doctor before using this medicine if you have liver or kidney disease.\n\nThe medication should not be used in patients with Type 1 diabetes or diabetic ketoacidosis.\n\nConclusion\n\nThe combination of Sitagliptin 50 mg, Metformin Hydrochloride 1000 mg, and Glimepiride 2 mg represents a powerful and balanced therapy for adults with Type 2 Diabetes Mellitus, especially those requiring triple-drug intervention to achieve desired glycemic control. Its multi-targeted approach ensures effective management of both fasting and postprandial glucose levels, thereby improving long-term metabolic health and reducing the risk of complications.",
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"description": "ST GLIPTIN GM is a high-quality, fixed-dose combination oral antidiabetic medication containing Sitagliptin 50 mg, Metformin Hydrochloride 1000 mg, and Glimepiride 1 mg. This triple-combination therapy is specifically formulated to provide effective glycemic control in adults with type 2 diabetes mellitus (T2DM) who require multiple agents to achieve adequate blood sugar control.\nST GLIPTIN GM works through complementary mechanisms to target the core pathophysiological defects of T2DM—insulin resistance, impaired insulin secretion, and increased hepatic glucose output—making it an ideal choice for patients requiring intensified therapy.\nKey Indications:\nST GLIPTIN GM is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus when dual therapy with any two of the individual components (Sitagliptin, Metformin, or Glimepiride) does not provide adequate control.\nMechanism of Action:\nSitagliptin (50 mg):\nA Dipeptidyl Peptidase-4 (DPP-4) inhibitor that enhances the levels of active incretin hormones (GLP-1 and GIP), increasing insulin release and decreasing glucagon secretion in a glucose-dependent manner.\nMetformin Hydrochloride (1000 mg):\nA biguanide that improves insulin sensitivity by decreasing hepatic glucose production and enhancing peripheral glucose uptake.\nGlimepiride (1 mg):\nA sulfonylurea that stimulates pancreatic β-cells to secrete insulin, thereby reducing blood glucose levels.\nThe combination targets multiple metabolic pathways to provide synergistic and sustained blood glucose control.\nDosage and Administration:\nRecommended Dose:\nOne tablet daily, preferably with meals to reduce gastrointestinal side effects.\nIndividualization Required:\nDosage should be tailored based on patient response, renal function, and physician assessment.\nRenal Monitoring:\nBaseline and periodic assessment of renal function is advised, particularly due to the metformin component.\nKey Benefits of ST GLIPTIN GM 50/1000/1:\nTriple Mechanism of Action:\nTargets insulin resistance, insufficient insulin secretion, and excessive hepatic glucose production.\nEnhanced Glycemic Control:\nEffective in achieving and maintaining HbA1c targets.\nOnce-Daily Convenience:\nImproves adherence by reducing pill burden in patients requiring combination therapy.\nWeight Neutral to Modest Reduction:\nMetformin and sitagliptin components support weight neutrality.\nLow Hypoglycemia Risk:\nSitagliptin and metformin carry minimal hypoglycemia risk; however, glimepiride may increase the risk—monitor accordingly.\nSafety and Precautions:\nHypoglycemia:\nMay occur, particularly due to the glimepiride component. Educate patients on recognizing and managing low blood sugar.\nLactic Acidosis:\nA rare but serious complication of metformin. Avoid in patients with significant renal impairment or conditions predisposing to hypoxia.\nRenal Function:\nDose adjustment or discontinuation may be needed based on renal function.\nPancreatitis:\nRare reports with DPP-4 inhibitors like sitagliptin. Discontinue if suspected.\nAllergic Reactions:\nDiscontinue use if hypersensitivity reactions occur.\nPossible Side Effects:\nWhile ST GLIPTIN GM is generally well-tolerated, some patients may experience:\nNausea\nDiarrhea\nHeadache\nHypoglycemia (especially in elderly or with missed meals)\nAbdominal discomfort\nUpper respiratory tract infections\nDizziness\nFlatulence\nIf any side effects persist or worsen, seek immediate medical advice.\nStorage Instructions:\nStore at a temperature below 30°C.\nProtect from moisture and direct sunlight.\nKeep out of reach of children.\nWhy Choose ST GLIPTIN GM 50/1000/1?\nST GLIPTIN GM provides a powerful and synergistic combination of three well-established antidiabetic agents in a single, convenient daily dose. It offers a comprehensive approach to managing type 2 diabetes by addressing multiple metabolic abnormalities with a focus on safety, efficacy, and patient compliance. Manufactured under stringent GMP-certified conditions, ST GLIPTIN GM ensures quality, reliability, and therapeutic confidence for both patients and prescribers.",
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"description": "Sitagliptin 50mg, Metformin Hydrochloride 500mg & Glimepiride 2mg is a combination oral medication designed for the effective management of type 2 diabetes mellitus. This triple-action formula works synergistically to control blood glucose levels by addressing insulin resistance, enhancing insulin secretion, and regulating post-meal sugar spikes. Ideal for patients who require more than one mechanism to maintain stable blood sugar, this combination is often prescribed when monotherapy or dual therapy is insufficient.\n\nUses\n\nManagement of Type 2 Diabetes Mellitus in adults.\n\nHelps in controlling fasting and postprandial blood glucose levels.\n\nRecommended for patients whose blood sugar is not adequately controlled with a single antidiabetic medicine.\n\nCan be used as part of a comprehensive diabetes management plan, including diet and exercise.\n\nKey Benefits\n\nDual Mechanism Control:\n\nMetformin Hydrochloride reduces hepatic glucose production and improves insulin sensitivity.\n\nGlimepiride stimulates pancreatic beta cells to secrete more insulin.\n\nSitagliptin enhances incretin hormones, leading to better regulation of post-meal glucose levels.\n\nEffective Blood Sugar Management:\nHelps maintain optimal fasting and postprandial glucose levels, reducing the risk of diabetes-related complications.\n\nConvenient Combination Therapy:\nCombines three mechanisms in a single tablet, reducing the pill burden and improving patient compliance.\n\nSupports Overall Health:\nHelps prevent long-term complications such as neuropathy, nephropathy, retinopathy, and cardiovascular risks associated with diabetes.\n\nPossible Side Effects\n\nWhile generally well-tolerated, some patients may experience:\n\nGastrointestinal issues: nausea, vomiting, diarrhea, or abdominal discomfort (mainly from Metformin).\n\nHypoglycemia (low blood sugar): more likely due to Glimepiride; symptoms include dizziness, sweating, or shakiness.\n\nAllergic reactions: rash, itching, or swelling in rare cases.\n\nOther mild effects: headache, fatigue, or minor changes in taste.\n\nNote: Patients should always consult their doctor before starting this combination and report any unusual symptoms immediately.\n\nConclusion\n\nThe Sitagliptin, Metformin Hydrochloride & Glimepiride combination provides a powerful, multi-targeted approach to managing type 2 diabetes. By tackling high blood sugar from different angles, it supports better glucose control, enhances overall quality of life, and reduces the risk of diabetes-related complications. When used alongside proper diet, exercise, and medical guidance, this combination can be a cornerstone in effective diabetes management.",
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