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{ "products": [ { "_id": "69902dc8911df6d4b0db4385", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Trazodone Hydrochloride 50 mg", "description": "TORRANE 50 is a pharmaceutical formulation containing Trazodone Hydrochloride 50 mg as its active ingredient. This medication belongs to the class of serotonin antagonist and reuptake inhibitors (SARIs), primarily prescribed for the management of major depressive disorder and associated sleep disturbances. TORRANE 50 represents a trusted therapeutic option that has been helping individuals regain emotional balance and improve their quality of life for decades. The medication works by modulating serotonin levels in the brain, offering relief from depression while simultaneously addressing insomnia that often accompanies mood disorders.\nUnderstanding Trazodone Hydrochloride\nTrazodone Hydrochloride is a unique antidepressant that distinguishes itself from other medications in its class through its dual-action mechanism. Unlike traditional selective serotonin reuptake inhibitors (SSRIs), TORRANE 50 not only helps restore serotonin balance but also possesses sedative properties that make it particularly valuable for patients struggling with both depression and sleep difficulties. The 50mg dosage represents a common starting point for treatment, allowing healthcare providers to carefully titrate the dose according to individual patient needs and responses.\nPrimary Uses and Applications\nTORRANE 50 serves multiple therapeutic purposes, making it a versatile option in psychiatric and general medical practice. The primary indication for this medication is major depressive disorder, where it helps alleviate symptoms such as persistent sadness, loss of interest in daily activities, feelings of worthlessness, and difficulty concentrating. Beyond its antidepressant properties, TORRANE 50 has gained significant recognition for its effectiveness in treating insomnia, particularly when sleep disturbances are related to depression or anxiety.\nHealthcare providers may also prescribe TORRANE 50 off-label for various conditions including generalized anxiety disorder, panic disorder, and chronic pain conditions where sleep disturbance is a prominent feature. The medication's ability to improve sleep architecture without the dependency risks associated with traditional benzodiazepines makes it an attractive option for long-term management of sleep-related issues.\nKey Benefits and Therapeutic Advantages\nThe benefits of TORRANE 50 extend far beyond simple symptom management, offering patients a comprehensive approach to mental health wellness. One of the most significant advantages is its dual-action profile, addressing both mood and sleep disturbances simultaneously. This is particularly beneficial because depression and insomnia often exist in a cyclical relationship, where each condition exacerbates the other.\nTORRANE 50 demonstrates a relatively favorable side effect profile compared to some other antidepressants, with lower risks of sexual dysfunction, which is a common concern with many SSRI medications. This makes it an excellent alternative for patients who have experienced these troublesome side effects with other antidepressants. Additionally, the medication is not associated with significant weight gain in most patients, addressing another common concern that can affect medication adherence.\nThe sedative properties of TORRANE 50, while beneficial for sleep, are dose-dependent, allowing physicians to customize treatment strategies. At lower doses, the medication primarily promotes sleep, while higher doses deliver more pronounced antidepressant effects. This flexibility enables healthcare providers to tailor treatment to individual patient needs effectively.\nAnother notable benefit is that TORRANE 50 has a relatively low potential for abuse compared to benzodiazepines and other sleep medications, making it safer for long-term use in appropriate patients. The medication also begins to improve sleep quality relatively quickly, often within the first week of treatment, though the full antidepressant effects may take several weeks to manifest fully.\nPotential Side Effects and Considerations\nLike all medications, TORRANE 50 may cause side effects, though not everyone experiences them. Understanding these potential effects helps patients and healthcare providers work together to optimize treatment outcomes. Common side effects include drowsiness and dizziness, particularly when starting the medication or increasing the dose. These effects are often most pronounced in the first few days of treatment and typically diminish as the body adjusts to the medication.\nSome patients may experience dry mouth, blurred vision, constipation, or headaches. These anticholinergic effects are generally mild and manageable. Nausea and gastrointestinal discomfort can occur, particularly if the medication is taken on an empty stomach. Taking TORRANE 50 with food can help minimize these digestive concerns.\nMore serious but less common side effects include orthostatic hypotension, which is a sudden drop in blood pressure upon standing that can lead to dizziness or fainting. Patients, especially older adults, should be cautioned to rise slowly from sitting or lying positions. In rare cases, TORRANE 50 may cause priapism, a prolonged and painful erection requiring immediate medical attention.\nCardiac considerations include potential changes in heart rhythm, and patients with pre-existing heart conditions should be monitored carefully. Some individuals may experience changes in alertness or cognitive function, which can affect the ability to drive or operate machinery safely, particularly when first starting treatment.\nAs with many antidepressants, there is a theoretical risk of increased suicidal thoughts, particularly in young adults and adolescents during the initial weeks of treatment. Close monitoring during this period is essential, and patients should immediately report any worsening of depression or emergence of suicidal thoughts.\nImportant Safety Information\nPatients should inform their healthcare provider about all medications, supplements, and herbal products they are taking, as TORRANE 50 can interact with numerous substances. Particularly significant interactions occur with monoamine oxidase inhibitors (MAOIs), other antidepressants, blood thinners, and medications affecting the central nervous system. Alcohol should be avoided during treatment as it can intensify sedation and increase the risk of adverse effects.\nTORRANE 50 should not be stopped abruptly without medical supervision, as discontinuation syndrome can occur, causing symptoms such as anxiety, agitation, and sleep disturbances. Healthcare providers will typically recommend gradual dose reduction when discontinuing the medication.\nConclusion\nTORRANE 50 (Trazodone Hydrochloride 50 mg) represents a valuable therapeutic option for individuals struggling with depression and sleep disturbances. Its unique dual-action mechanism, addressing both mood regulation and sleep quality, sets it apart in the landscape of psychiatric medications. The favorable side effect profile, particularly regarding sexual function and weight concerns, combined with its low abuse potential, makes TORRANE 50 an attractive choice for both patients and healthcare providers.", "price": 76.0, "discountamount": 23.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2305, "imageuri": "https://productimages.withfloats.com/actual/69902dca78523277e04db86e.png", "tileimageuri": "https://productimages.withfloats.com/tile/69902dca78523277e04db86e.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-02-14T08:09:44.427Z", "updatedon": "2026-03-13T07:58:53.427Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/trazodone-hydrochloride-50-mg/2305", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "TORRANE 50", "category": "NEUROLOGYRANGE", "tags": [ "trazodone hydrochloride 50 mg tablet uses", "what is trazodone hydrochloride 50 mg prescribed for", "trazodone hydrochloride 50 mg for insomnia reviews", "trazodone hydrochloride 50 mg for anxiety dosage", "is trazodone hydrochloride 50 mg enough for sleep", "trazodone hydrochloride 50 mg weight gain", "can you take trazodone hydrochloride 50 mg every night", "trazodone hydrochloride 50 mg withdrawal symptoms", "trazodone hydrochloride 50 mg overdose risk", "buy trazodone hydrochloride 50 mg online prescription", "trazodone hydrochloride 50 mg price without insurance", "trazodone hydrochloride 50 mg manufacturer", "trazodone hydrochloride 50 mg vs mirtazapine" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69623e6c95697555dd1afd67", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Esomeprazole and Itopride", "description": "ESMOSTRUM IT: Comprehensive Product Guide\nProduct Overview\nESMOSTRUM IT is an advanced pharmaceutical formulation that combines two potent active ingredients—Esomeprazole and Itopride—to provide comprehensive relief from gastrointestinal disorders. This dual-action medication represents a significant advancement in the management of acid-related digestive conditions and motility disorders. By combining a proton pump inhibitor with a prokinetic agent, ESMOSTRUM IT addresses both the underlying causes and symptomatic manifestations of various digestive ailments, offering patients a complete therapeutic solution in a single, convenient dosage form.\nThe synergistic combination of Esomeprazole and Itopride makes ESMOSTRUM IT particularly effective for individuals suffering from gastroesophageal reflux disease (GERD), functional dyspepsia, and other conditions where both excessive acid production and impaired gastric motility contribute to discomfort and disease progression.\nActive Pharmaceutical Ingredients\nEsomeprazole\nEsomeprazole is the S-isomer of omeprazole and belongs to the class of medications known as proton pump inhibitors (PPIs). It works by specifically and irreversibly blocking the hydrogen-potassium adenosine triphosphatase enzyme system (the proton pump) located in the gastric parietal cells. This mechanism effectively reduces gastric acid secretion, providing sustained relief from acid-related symptoms and allowing damaged esophageal and gastric tissue to heal.\nItopride\nItopride is a prokinetic agent that enhances gastrointestinal motility through a dual mechanism of action. It acts as both a dopamine D2 receptor antagonist and an acetylcholinesterase inhibitor. By blocking dopamine receptors, it removes the inhibitory effect of dopamine on gastrointestinal motility, while its acetylcholinesterase inhibition increases acetylcholine levels, further promoting coordinated gastric contractions and improved gastric emptying.\nTherapeutic Uses and Indications\nESMOSTRUM IT is prescribed for a wide range of gastrointestinal conditions where both acid suppression and enhanced motility are therapeutically beneficial:\nGastroesophageal Reflux Disease (GERD)\nESMOSTRUM IT provides exceptional relief for patients suffering from GERD, a chronic condition where stomach acid frequently flows back into the esophagus. The esomeprazole component reduces acid production, while itopride improves the tone of the lower esophageal sphincter and accelerates gastric emptying, thereby reducing the frequency and severity of reflux episodes.\nFunctional Dyspepsia\nFor patients experiencing persistent or recurrent upper abdominal discomfort without an identifiable organic cause, ESMOSTRUM IT addresses multiple pathophysiological mechanisms. It relieves symptoms such as early satiety, postprandial fullness, epigastric pain, and bloating by normalizing gastric acid levels and improving gastric accommodation and emptying.\nPeptic Ulcer Disease\nESMOSTRUM IT aids in the healing of gastric and duodenal ulcers by creating an optimal healing environment through sustained acid suppression. The prokinetic action of itopride helps prevent stasis of gastric contents, which can exacerbate ulcer symptoms.\nNon-Ulcer Dyspepsia\nMany patients experience dyspeptic symptoms without evidence of ulceration. ESMOSTRUM IT effectively manages these symptoms by addressing both acid hypersecretion and delayed gastric emptying, two key factors in non-ulcer dyspepsia.\nGastroparesis-Related Symptoms\nIn conditions where gastric emptying is significantly delayed, the itopride component of ESMOSTRUM IT helps restore more normal gastric motility patterns, reducing associated symptoms like nausea, vomiting, and abdominal distension.\nKey Benefits and Advantages\nDual Mechanism of Action\nThe primary advantage of ESMOSTRUM IT lies in its comprehensive approach to gastrointestinal health. Rather than addressing only acid production or motility in isolation, this combination therapy tackles both aspects simultaneously, providing more complete symptom relief and better therapeutic outcomes.\nSuperior Acid Suppression\nEsomeprazole offers more consistent and prolonged acid suppression compared to many other acid-reducing medications. It provides sustained relief throughout the day and night, allowing patients to experience fewer breakthrough symptoms and better quality of life.\nEnhanced Gastric Motility\nThe itopride component specifically targets motility issues without crossing the blood-brain barrier significantly, meaning it provides prokinetic benefits with minimal central nervous system side effects. This results in improved gastric emptying, reduced bloating, and decreased feelings of fullness after meals.\nRapid Symptom Relief\nMany patients experience noticeable improvement in their symptoms within the first few days of treatment with ESMOSTRUM IT. The combination therapy addresses multiple symptom pathways simultaneously, leading to faster and more comprehensive relief.\nImproved Quality of Life\nBy effectively managing symptoms such as heartburn, regurgitation, nausea, bloating, and early satiety, ESMOSTRUM IT significantly enhances patients' daily functioning and overall well-being. Patients report better sleep quality, improved dietary tolerance, and reduced anxiety related to their digestive symptoms.\nConvenient Dosing\nThe combination of two active ingredients in a single formulation improves medication adherence by reducing pill burden. Patients appreciate the simplicity of taking one medication instead of multiple separate preparations.\nMucosal Healing Properties\nBeyond symptom relief, ESMOSTRUM IT promotes actual healing of damaged esophageal and gastric mucosa. The reduced acid environment created by esomeprazole allows inflamed and eroded tissue to regenerate properly.\nReduced Risk of Complications\nBy effectively controlling acid reflux and improving gastric emptying, ESMOSTRUM IT helps prevent potential complications of chronic GERD, such as esophageal strictures, Barrett's esophagus, and respiratory complications from aspiration.\nDosage and Administration\nESMOSTRUM IT should be taken exactly as prescribed by a healthcare professional. Typically, the medication is administered orally, preferably before meals to optimize its therapeutic effects. The standard dosing regimen usually involves once or twice daily administration, though individual requirements may vary based on the severity of the condition and patient response.\nThe medication should be swallowed whole with water and should not be crushed, chewed, or split, as this may affect the drug's release mechanism and therapeutic efficacy. Patients should maintain regular dosing schedules to ensure optimal acid suppression and motility enhancement throughout the day.\nSide Effects and Safety Considerations\nLike all medications, ESMOSTRUM IT may cause side effects in some individuals, though not everyone experiences them. Understanding potential adverse effects helps patients identify and report concerning symptoms promptly.\nCommon Side Effects\nGastrointestinal Effects: Some patients may experience diarrhea, constipation, abdominal pain, nausea, or flatulence, particularly during initial treatment. These effects are usually mild and often resolve as the body adjusts to the medication.\nHeadache: Mild to moderate headaches occur in a small percentage of patients and typically diminish with continued use.\nDizziness: Some individuals may experience lightheadedness or dizziness, particularly when standing up quickly.\nDry Mouth: Reduced saliva production may occur, leading to oral dryness and discomfort.\nLess Common Side Effects\nSkin Reactions: Rash, itching, or other dermatological manifestations may develop in sensitive individuals.\nSleep Disturbances: Some patients report insomnia or unusual dreams while taking the medication.\nIncreased Prolactin Levels: Itopride may cause mild elevation in prolactin levels, though clinical manifestations are rare.\nTaste Alterations: Changes in taste perception or metallic taste may occur temporarily.\nSerious Side Effects (Rare)\nWhile uncommon, certain serious adverse effects require immediate medical attention:\n\nSevere allergic reactions including difficulty breathing, facial swelling, or severe skin reactions\nSevere diarrhea that persists or contains blood\nIrregular heartbeat or palpitations\nMuscle weakness or pain\nSeizures or tremors\nSigns of liver problems including jaundice, dark urine, or persistent nausea\n\nLong-Term Considerations\nExtended use of proton pump inhibitors like esomeprazole has been associated with certain risks that patients should discuss with their healthcare providers:\n\nPotential reduction in calcium, magnesium, and vitamin B12 absorption\nSlightly increased risk of bone fractures with prolonged use\nPossible increased susceptibility to certain gastrointestinal infections\nRare cases of kidney problems\n\nRegular monitoring and periodic assessment by healthcare professionals help minimize these risks while maintaining therapeutic benefits.\nPrecautions and Contraindications\nPatients should inform their healthcare provider about all existing medical conditions, particularly liver disease, kidney problems, osteoporosis, low magnesium levels, or any gastrointestinal bleeding. ESMOSTRUM IT may interact with certain medications, including blood thinners, antifungals, HIV medications, and certain antibiotics. A complete medication review ensures safe and effective therapy.\nPregnant or breastfeeding women should only use ESMOSTRUM IT under strict medical supervision, as the safety profile in these populations requires careful consideration of potential risks and benefits.\nLifestyle Recommendations\nFor optimal therapeutic outcomes, patients taking ESMOSTRUM IT should complement their medication regimen with appropriate lifestyle modifications:\n\nAvoid trigger foods that exacerbate acid reflux, such as spicy foods, citrus, chocolate, caffeine, and alcohol\nMaintain a healthy body weight to reduce abdominal pressure\nEat smaller, more frequent meals rather than large portions\nAvoid lying down immediately after eating; wait at least two to three hours\nElevate the head of the bed if nighttime symptoms occur\nQuit smoking, as tobacco use significantly worsens reflux symptoms\nManage stress through relaxation techniques, as stress can exacerbate digestive symptoms\n\nConclusion\nESMOSTRUM IT represents a sophisticated and effective pharmaceutical solution for individuals struggling with complex gastrointestinal disorders involving both acid hypersecretion and impaired motility. By combining the powerful acid-suppressing capabilities of esomeprazole with the prokinetic benefits of itopride, this medication offers comprehensive symptom management that addresses the multifaceted nature of digestive disorders.", "price": 182.0, "discountamount": 54.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2273, "imageuri": "https://productimages.withfloats.com/actual/69623e6fd8491171373812e3.png", "tileimageuri": "https://productimages.withfloats.com/tile/69623e6fd8491171373812e3.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-10T11:56:28.061Z", "updatedon": "2026-04-21T09:38:56.999Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//esomeprazole-and-itopride/2273", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "ESMOSTRUM IT", "category": "GASTROLOGYRANGE", "tags": [ "esomeprazole and itopride", "esomeprazole and itopride capsules uses in hindi", "esomeprazole and itopride capsules uses", "esomeprazole and itopride brand name", "esomeprazole and itopride hydrochloride", "esomeprazole and itopride capsules", "esomeprazole and itopride uses", "esomeprazole and itopride hydrochloride capsules", "esomeprazole and itopride hydrochloride uses", "esomeprazole and itopride hydrochloride price", "esomeprazole and itopride hydrochloride price in india", "buy online Esomeprazole and Itopride" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6957b1f01063d98b1e8f2f17", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Opipramol Dihydrochloride 100 mg", "description": "OPIRAPROL 100, featuring Opipramol Dihydrochloride 100 mg, stands out as a reliable medication from Steris Healthcare Pvt Ltd designed to address anxiety disorders and related somatic issues. This tricyclic compound offers targeted relief by modulating brain chemicals for better emotional balance. Patients often find it helps restore daily functionality without the heavier sedation of some alternatives.\n​\n\nProduct Overview\nOPIRAPROL 100 contains 100 mg of Opipramol Dihydrochloride per tablet, a dibenzazepine derivative primarily classified as an anxiolytic with antidepressant properties. Manufactured by Steris Healthcare Pvt Ltd, it targets generalized anxiety disorder (GAD) and somatoform disorders, where physical symptoms like unexplained pain or fatigue stem from psychological stress. Unlike typical antidepressants that focus solely on serotonin reuptake, Opipramol acts as a sigma-1 receptor agonist, influencing calcium signaling and neurotransmitter release for a calming effect.\n​\n\nThe formulation ensures steady absorption, making it suitable for adults needing moderate to higher dosing. Each pack typically includes 10 tablets, priced accessibly for ongoing therapy under medical supervision. Steris emphasizes quality with WHO-GMP certification, positioning OPIRAPROL 100 as a trusted option in India's mental health market.\n​\n\nHow It Works\nOpipramol Dihydrochloride in OPIRAPROL 100 primarily binds to sigma receptors in the brain, promoting translocation to cell membranes and enhancing neurotransmitter modulation, especially serotonin and dopamine. This biphasic action first reduces acute tension and insomnia, then stabilizes mood over time by downregulating sigma-2 sites during chronic use.\n​\n\nIt also exhibits mild antihistamine and anticholinergic effects, contributing to its sedative properties without strong reuptake inhibition like classic tricyclics. By calming overactive neural pathways, it alleviates the cycle of worry and physical unease, allowing clearer thinking and restful sleep. Clinical studies highlight its efficacy in somatoform cases, where patients fixate on bodily sensations amplified by anxiety.\n​\n\nKey Uses\nHealthcare providers prescribe OPIRAPROL 100 for several interconnected conditions rooted in anxiety.\n\nGeneralized anxiety disorder, easing excessive worry, restlessness, and irritability that disrupt work and relationships.\n​\n\nSomatoform disturbances target fatigue, pain, or gastrointestinal issues without clear organic cause.\n​\n\nMild depressive episodes with prominent anxiety, supporting mood without full antidepressant escalation.\n​\n\nAdjunctive therapy for sleep bruxism or insomnia linked to stress, based on emerging evidence.\n​\n\nIn practice, it suits patients in high-stress environments, like urban professionals in Jaipur facing daily pressures, helping them regain focus and productivity.\n​\n\nKey Benefits\nUsers of OPIRAPROL 100 report transformative effects that extend beyond symptom relief.\n\nRapid anxiety reduction promotes mental clarity, enabling better concentration and decision-making in daily tasks.\n​\n\nMood stabilization balances emotional swings, fostering stronger interpersonal connections and resilience.\n​\n\nEnhanced sleep quality combats insomnia, leading to refreshed mornings and sustained energy.\n​\n\nImproved daily functioning boosts productivity, which is vital for professionals balancing career and personal life.\n​\n\nLower sedation profile compared to benzodiazepines allows safe use during daytime hours.\n​\n\nLong-term, it enhances quality of life by breaking anxiety cycles, with many patients noting fewer somatic complaints after consistent use.\n​\n\nDosage Guidelines\nTake OPIRAPROL 100 as directed, typically 100 mg once or twice daily for adults, swallowed whole with water, with or without food. Start low to assess tolerance, adjusting up to 300 mg daily for severe cases under supervision.\n​\n\nFor children over 6, dosing follows 3 mg/kg body weight, but adult use predominates. Maintain consistent timing to stabilize blood levels, and taper gradually to avoid withdrawal. Missed doses should resume normally without doubling.\n\nPotential Side Effects\nMost side effects of OPIRAPROL 100 are mild and diminish with time, but monitoring remains essential.\n\nCommon ones (1-10%) include dry mouth, nasal congestion, fatigue, dizziness, and orthostatic hypotension, often resolving as the body adjusts.\n\nOccasional (0.1-1%) effects encompass constipation, weight gain, tremor, blurred vision, tachycardia, and mild liver enzyme elevation.\nRare issues (<0.1%) like allergic rashes, urinary retention, confusion, or leukopenia require immediate medical attention, especially in elderly patients or those with heart conditions.\n​\nPrecautions\nAvoid OPIRAPROL 100 in acute glaucoma, urinary retention, ileus, or uncontrolled epilepsy due to anticholinergic risks.\n​\nPregnant or lactating women need doctor approval, as safety data limits use. Steer clear of alcohol and CNS depressants to prevent amplified drowsiness.\n\nMonitor heart rhythm in bradycardia patients and liver function during prolonged therapy. Abrupt stops can trigger rebound anxiety.\nWhen to Consult a Doctor\nSeek prompt advice if side effects intensify, mood worsens paradoxically, or new symptoms like chest pain emerge. Regular check-ins ensure optimal dosing, particularly for those on interacting meds like MAOIs.\n​\nConclusion\nOPIRAPROL 100 with Opipramol Dihydrochloride 100 mg delivers effective, balanced relief for anxiety and somatic disorders, empowering users toward calmer, more productive lives. Backed by Steris Healthcare's commitment to quality, it bridges the gap between symptom management and holistic well-being when used responsibly. Always prioritize professional guidance to maximize benefits while minimizing risks.\n", "price": 154.0, "discountamount": 46.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2259, "imageuri": "https://productimages.withfloats.com/actual/6957b22c6b1ead52de1e2df4.png", "tileimageuri": "https://productimages.withfloats.com/tile/6957b22c6b1ead52de1e2df4.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-02T11:54:24.869Z", "updatedon": "2026-03-13T07:53:58.661Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//opipramol-dihydrochloride-100-mg/2259", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "OPIRAPROL 100", "category": "NEUROLOGYRANGE", "tags": [ "opipramol dihydrochloride.", "opipramol dihydrochloride tablets uses.", "opipramol dihydrochloride tablets uses in hindi.", "opipramol dihydrochloride tablets.", "opipramol dihydrochloride uses.", "opipramol dihydrochloride side effects", "opipramol dihydrochloride tablet.", "what is opipramol dihydrochloride.", "side effects of opipramol dihydrochloride.", "opipramol dihydrochloride dosage.", "opipramol dihydrochloride tablet for anxiety disorder", "medicine for generalized anxiety disorder treatment", "tablet for anxiety and stress management", "medication for nervous tension and anxiety", "how opipramol dihydrochloride works for anxiety", "opipramol vs amitriptyline for anxiety", "medicines for stress and anxiety relief", "opipramol dihydrochloride tablets supplier india" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "694cf85408591c1173b54c2f", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Pregabalin Epalrestat and Methylcobalamin Tablets", "description": "EPSTATE ED represents an advanced pharmaceutical formulation that combines three powerful therapeutic agents: Pregabalin, Epalrestat, and Methylcobalamin. This innovative triple-combination medication is specifically designed to address the complex pathophysiology of diabetic neuropathy and neuropathic pain conditions. By integrating multiple mechanisms of action, EPSTATE ED offers a comprehensive approach to managing nerve-related complications that significantly impact the quality of life for millions of individuals worldwide.\nThe formulation addresses not only the symptomatic relief of neuropathic pain but also targets the underlying metabolic derangements that contribute to nerve damage progression. This multi-pronged therapeutic strategy makes EPSTATE ED particularly valuable for patients who require more than symptomatic management alone.\nUnderstanding the Active Components\nPregabalin: The Neuropathic Pain Modulator\nPregabalin serves as the cornerstone analgesic component in EPSTATE ED. This anticonvulsant medication works by binding to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. Through this mechanism, Pregabalin reduces the release of excitatory neurotransmitters including glutamate, norepinephrine, and substance P. This reduction in neurotransmitter release effectively dampens the abnormal neural signaling that characterizes neuropathic pain conditions.\nThe molecule demonstrates excellent bioavailability and rapid absorption, allowing patients to experience relief within a relatively short timeframe. Its efficacy in managing various neuropathic pain syndromes has been extensively documented in clinical trials, establishing it as a first-line agent for diabetic peripheral neuropathy, postherpetic neuralgia, and other chronic neuropathic pain conditions.\nEpalrestat: The Aldose Reductase Inhibitor\nEpalrestat represents a unique addition to the formulation, functioning as a selective aldose reductase inhibitor. In diabetic conditions, excess glucose is converted to sorbitol through the polyol pathway, with aldose reductase serving as the rate-limiting enzyme. The accumulation of sorbitol within nerve cells leads to osmotic stress, depletion of myoinositol, and subsequent nerve dysfunction.\nBy inhibiting aldose reductase, Epalrestat prevents this harmful sorbitol accumulation, thereby addressing one of the fundamental metabolic abnormalities responsible for diabetic neuropathy. This disease-modifying approach distinguishes EPSTATE ED from purely symptomatic treatments. Epalrestat has been particularly well-studied in Asian populations and has demonstrated the ability to improve nerve conduction velocities and reduce subjective neuropathic symptoms over time.\nMethylcobalamin: The Neurotropic Vitamin\nMethylcobalamin, the bioactive form of Vitamin B12, completes the therapeutic triad in EPSTATE ED. Unlike cyanocobalamin, which requires conversion in the body, methylcobalamin is immediately available for utilization in crucial biochemical processes. It plays an indispensable role in myelin synthesis, the protective sheath surrounding nerve fibers that enables proper signal transmission.\nThis coenzyme participates in methionine synthesis and is essential for maintaining the structural and functional integrity of neurons. Methylcobalamin also facilitates nerve regeneration and has demonstrated neuroprotective properties in various experimental models. For patients with diabetic neuropathy, who often exhibit Vitamin B12 deficiency (sometimes exacerbated by metformin therapy), supplementation with methylcobalamin addresses both nutritional deficits and supports nerve health at a fundamental level.\nClinical Applications and Uses\nEPSTATE ED is primarily indicated for the comprehensive management of diabetic peripheral neuropathy, a condition affecting approximately 50% of individuals with long-standing diabetes. The symptoms of this condition range from tingling sensations and burning pain to numbness and loss of protective sensation, which can lead to serious complications including foot ulcers and amputations.\nBeyond diabetic neuropathy, EPSTATE ED may be prescribed for various neuropathic pain syndromes where the combination of pain relief, metabolic correction, and nerve support proves beneficial. Patients experiencing chronic nerve pain resulting from metabolic disturbances, nutritional deficiencies, or structural nerve damage may find this combination particularly effective.\nThe medication is typically recommended for adults who have not achieved adequate symptom control with single-agent therapy or who would benefit from the synergistic effects of the three components. Healthcare providers may prescribe EPSTATE ED when a patient requires both immediate symptom relief and long-term disease modification.\nKey Benefits and Therapeutic Advantages\nComprehensive Multi-Mechanism Action\nThe primary advantage of EPSTATE ED lies in its multi-faceted approach to neuropathic conditions. Rather than addressing only pain symptoms, the formulation simultaneously tackles pain perception, underlying metabolic abnormalities, and nutritional support for nerve health. This comprehensive strategy may lead to superior outcomes compared to monotherapy approaches.\nEnhanced Pain Relief\nClinical evidence supporting Pregabalin's efficacy in neuropathic pain is substantial. Patients often report significant reductions in pain intensity, improved sleep quality due to decreased nocturnal pain, and enhanced ability to perform daily activities. The pain-relieving effects typically manifest within the first week of therapy and continue to improve with ongoing treatment.\nDisease Modification Potential\nUnlike purely symptomatic treatments, the inclusion of Epalrestat provides genuine disease-modifying potential. By targeting the polyol pathway, EPSTATE ED may slow the progression of nerve damage in diabetic patients. Long-term use may preserve nerve function and prevent the worsening of neuropathic symptoms, offering hope beyond mere symptom management.\nImproved Nerve Conduction and Function\nThe combination of metabolic correction through Epalrestat and neurotropic support via Methylcobalamin creates an environment conducive to nerve regeneration and functional improvement. Studies have demonstrated improvements in nerve conduction velocity parameters with similar combination therapies, suggesting potential restoration of nerve function rather than simple symptom masking.\nConvenience of Combination Therapy\nFor patients who would otherwise require multiple separate medications, EPSTATE ED offers the convenience of a single tablet containing all three therapeutic agents. This simplification of medication regimens improves compliance, reduces pill burden, and may enhance overall treatment outcomes.\nQuality of Life Enhancement\nThe cumulative effect of pain reduction, improved nerve function, and better metabolic control translates into meaningful quality of life improvements. Patients report better mobility, reduced interference of pain with daily activities, improved mood, and enhanced social functioning.\nPotential Side Effects and Safety Considerations\nCommon Side Effects\nAs with any pharmaceutical agent, EPSTATE ED may produce certain adverse effects. The most commonly reported side effects are primarily attributable to the Pregabalin component and include dizziness, somnolence, peripheral edema, dry mouth, blurred vision, weight gain, and difficulty with concentration or attention. These effects are generally mild to moderate and often diminish with continued therapy as the body adapts to the medication.\nGastrointestinal symptoms such as constipation or nausea may occur, though they are typically manageable with dietary modifications or symptomatic treatment. Some patients experience increased appetite leading to weight gain, which requires monitoring, particularly in diabetic individuals where weight management is crucial.\nSerious but Rare Adverse Events\nThough uncommon, certain serious adverse effects warrant immediate medical attention. These include allergic reactions manifesting as rash, itching, swelling, severe dizziness, or breathing difficulties. Pregabalin has been associated with rare cases of angioedema, which requires prompt discontinuation and medical intervention.\nMental health changes, including mood alterations, anxiety, depression, agitation, or suicidal thoughts, have been reported with Pregabalin use, particularly in individuals with pre-existing psychiatric conditions. Patients and caregivers should remain vigilant for behavioral changes and report them immediately to healthcare providers.\nDrug Interactions and Precautions\nEPSTATE ED may interact with other central nervous system depressants, including alcohol, opioids, benzodiazepines, and antihistamines, potentially intensifying sedation and cognitive impairment. Patients should inform their healthcare provider of all medications, supplements, and substances they consume.\nIndividuals with kidney impairment require dose adjustments since Pregabalin is primarily eliminated through renal excretion. Regular monitoring of renal function may be necessary during long-term therapy.\nSpecial Population Considerations\nPregnant or breastfeeding women should use EPSTATE ED only when clearly necessary and under strict medical supervision, as the safety profile in these populations has not been fully established. Elderly patients may be more susceptible to side effects, particularly dizziness and confusion, necessitating careful dose titration and monitoring.\nPatients should be advised against abrupt discontinuation of EPSTATE ED, as sudden cessation of Pregabalin may precipitate withdrawal symptoms including insomnia, nausea, headache, anxiety, and sweating. Gradual dose reduction under medical supervision is recommended when discontinuing therapy.\nDosage and Administration Guidelines\nThe appropriate dosage of EPSTATE ED is highly individualized and should be determined by a qualified healthcare professional based on the patient's specific condition, response to therapy, and tolerance. Typically, treatment begins with a lower dose that is gradually increased to achieve optimal therapeutic benefit while minimizing adverse effects.\nPatients should take EPSTATE ED exactly as prescribed, with or without food, at consistent times each day to maintain stable blood levels. Missing doses should be addressed by taking the forgotten dose as soon as remembered, unless it's nearly time for the next scheduled dose. Double dosing to compensate for missed doses is not recommended.\nRegular follow-up appointments allow healthcare providers to assess treatment efficacy, monitor for adverse effects, and make necessary dose adjustments. Patients should maintain open communication with their medical team regarding symptom improvement, side effects, and any concerns that arise during therapy.\nPatient Counseling and Lifestyle Recommendations\nMaximizing the benefits of EPSTATE ED extends beyond simply taking the medication. Patients should be counseled on complementary lifestyle measures that support neuropathy management. Maintaining optimal glycemic control remains paramount for diabetic patients, as blood sugar management directly impacts neuropathy progression regardless of medication.\nRegular physical activity, within individual capabilities, promotes circulation, supports nerve health, and may enhance the therapeutic effects of EPSTATE ED. Daily foot examinations become critical for diabetic patients to identify potential injuries early, preventing serious complications.\nNutritional optimization, including adequate intake of B vitamins, antioxidants, and essential nutrients, supports the neurotropic effects of Methylcobalamin. Avoiding alcohol and tobacco, both of which can exacerbate neuropathy, is strongly recommended.\nPatients should be cautioned about activities requiring alertness, such as driving or operating machinery, especially during the initial treatment phase when dizziness and somnolence may be more pronounced. These effects typically improve with continued therapy, but individual responses vary.\nConclusion\nEPSTATE ED represents a thoughtfully designed pharmaceutical formulation that addresses the multifaceted nature of diabetic neuropathy and neuropathic pain through its unique combination of Pregabalin, Epalrestat, and Methylcobalamin. This triple-action approach offers patients more than symptomatic relief—it provides genuine disease modification potential, nutritional support, and comprehensive nerve health optimization.\nThe synergistic effects of these three components create a therapeutic profile that is greater than the sum of its parts. While Pregabalin efficiently manages pain symptoms and improves quality of life in the short term, Epalrestat works to address underlying metabolic derangements that drive disease progression, and Methylcobalamin provides essential neurotropic support for nerve regeneration and function.\nFor patients struggling with the debilitating effects of neuropathic pain and diabetic neuropathy, EPSTATE ED offers renewed hope for better symptom control and potentially slowed disease progression. The convenience of combination therapy in a single tablet improves adherence and simplifies complex treatment regimens.\nHowever, EPSTATE ED is not without considerations. Potential side effects, though generally manageable, require awareness and monitoring. The medication is most effective when integrated into a comprehensive management plan that includes optimal glycemic control, lifestyle modifications, and regular medical supervision.\nUltimately, EPSTATE ED should be viewed as a valuable tool in the therapeutic arsenal against neuropathic conditions, best utilized under the guidance of knowledgeable healthcare professionals who can individualize treatment to each patient's unique needs and circumstances. With proper use, monitoring, and patient education, EPSTATE ED can significantly improve outcomes and quality of life for those affected by these challenging neurological conditions.", "price": 275.0, "discountamount": 82.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2253, "imageuri": "https://productimages.withfloats.com/actual/694cf859d25fa0b0657b1ac8.png", "tileimageuri": "https://productimages.withfloats.com/tile/694cf859d25fa0b0657b1ac8.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-25T08:39:48.947Z", "updatedon": "2026-04-18T09:21:49.885Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//pregabalin-epalrestat-and-methylcobalamin-tablets/2253", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "EPSTATE ED", "category": "NEUROLOGYRANGE", "tags": [ "regabalin, Epalrestat, and Methylcobalamin.neuropathic pain conditions.", "Pregabalin, Epalrestat, and Methylcobalamin.", "neuropathic pain.", "diabetic neuropathy.", "sorbitol within nerve cells leads to osmotic stress.", "Epalrestat and neurotropic support via Methylcobalamin creates an environment .", "mood alterations, anxiety, depression, agitation.", "supports the neurotropic effects of Methylcobalamin.", "Pregabalin Epalrestat and Methylcobalamin Tablets", "epalrestat and methylcobalamin tablets uses", "epalrestat and methylcobalamin tablets in hindi", "pregabalin epalrestat and methylcobalamin tablets price jaipur", "pregabalin epalrestat and methylcobalamin tablets price india" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "691b17834c6b1fd261aeaae2", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Dothiepin 75mg and Methylcobalamin 1500mcg | DROTHEPINE M 75", "description": "DROTHEPINE M 75 is a clinically formulated combination that unites the therapeutic strength of Dothiepin 75mg, a tricyclic antidepressant, with Methylcobalamin 1500 mcg, an essential neurovitamin known for its nerve-repairing properties. This high-strength formulation is designed to support individuals facing depression, anxiety, neuropathic pain, and nerve degeneration associated with vitamin B12 deficiency. Dothiepin works by restoring chemical balance in the brain to improve mood, sleep, and emotional well-being. Meanwhile, Methylcobalamin helps repair damaged nerves and enhances nerve conduction. Together, these components make DROTHEPINE M 75 a comprehensive solution for boosting both mental health and neurological function.\n\nUses\nDROTHEPINE M 75 is recommended for the treatment and management of several psychological and nerve-related conditions. Its primary uses include:\nTreatment of Major Depression and Anxiety Disorders: Helps reduce persistent sadness, irritability, and emotional instability.\n\nManagement of Neuropathic Pain: Effective for nerve pain caused by diabetes, injuries, and chronic nerve damage.\n\nCorrection of Vitamin B12 Deficiency: Supports proper nerve functioning in individuals with low B12 levels.\n\nRelief from Nerve Tingling, Burning, and Numbness: Ideal for managing peripheral neuropathy symptoms.\n\nSupport for Sleep Disturbances Linked to Stress or Depression: Promotes relaxation and improves sleep quality.\n\nThese multifaceted uses make DROTHEPINE M 75 a trusted choice for patients needing both emotional and neurological support.\n\nBenefits\n\nThe powerful combination of Dothiepin 75mg and Methylcobalamin 1500mcg delivers a wide range of therapeutic benefits:\n\n1. Enhanced Mood Regulation\n\nDothiepin helps restore the balance of neurotransmitters like serotonin and norepinephrine, providing relief from depression and anxiety while enhancing overall emotional stability.\n\n2. Supports Nerve Regeneration\n\nMethylcobalamin promotes nerve cell repair, improves nerve signaling, and helps reduce neuropathic pain more effectively than standard B12 forms.\n\n3. Dual Action for Mental and Nerve Health\n\nBy targeting both emotional and physical discomfort, DROTHEPINE M 75 offers holistic relief, making daily life more manageable.\n\n4. Improved Sleep and Cognitive Clarity\n\nThe antidepressant component reduces stress-related sleep disturbances and supports improved focus, concentration, and memory.\n\n5. Best-in-Class Strength for Long-Lasting Relief\n\nWith a higher 75mg dose of Dothiepin, this formulation provides sustained action throughout the day, delivering dependable symptom control.\n\nDosage\n\nThe typical recommended dosage of DROTHEPINE M 75 is one tablet once daily, or as directed by a healthcare professional.\n\nTake the tablet with water, preferably after meals to reduce gastrointestinal discomfort.\n\nDosage may differ based on individual needs, severity of symptoms, and medical history.\n\nConsistency is key—take the medication at the same time each day for optimal results.\n\nDo not increase, reduce, or stop the dosage abruptly without consulting a doctor.\n\nSide Effects\n\nAlthough DROTHEPINE M 75 is generally well-tolerated, some individuals may experience mild side effects, especially at the beginning of treatment. These may include:\n\nDrowsiness or dizziness\n\nDry mouth\n\nConstipation\n\nBlurred vision\n\nFatigue or tiredness\n\nIncreased appetite or weight changes\n\nMild nausea or headache\n\nSevere side effects are uncommon, but seek immediate medical attention if you experience irregular heartbeat, severe dizziness, allergic reactions, or sudden mood changes.\n\nPrecautions and Warning\n\nAvoid alcohol while taking this medication, as it may intensify drowsiness and impair alertness.\n\nNot recommended during pregnancy or breastfeeding unless prescribed by a healthcare provider.\n\nPeople with heart problems, glaucoma, epilepsy, liver disease, or urinary retention must inform their doctor before use.\n\nThis medicine may cause drowsiness—avoid driving or operating machinery until you know how it affects you.\n\nDo not discontinue the medicine abruptly; dosage reduction should be supervised by a doctor.\n\nKeep the medication stored in a cool, dry place away from children.\n\nConclusion\n\nDROTHEPINE M 75, formulated with Dothiepin 75mg and Methylcobalamin 1500 mcg, is an advanced dual-action therapy designed to support emotional well-being and nerve health simultaneously. It effectively treats depression, anxiety, neuropathic pain, and vitamin B12 deficiency while promoting nerve repair and cognitive clarity. When taken under medical supervision, this powerful combination helps restore balance, reduce discomfort, and improve your overall quality of life.", "price": 360.0, "discountamount": 108.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2209, "imageuri": "https://productimages.withfloats.com/actual/691b1786743983a7e3b55dc4.png", "tileimageuri": "https://productimages.withfloats.com/tile/691b1786743983a7e3b55dc4.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-17T12:39:31.538Z", "updatedon": "2026-05-20T11:51:33.395Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//dothiepin-75mg-and-methylcobalamin-1500mcg-drothepine-m-75/2209", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "DROTHEPINE M 75", "category": "NEUROLOGYRANGE", "tags": [ "DROTHEPINE M 75", "Depression and Anxiety Disorders", "Dothiepin 75mg", "Methylcobalamin 1500 mcg", "neuropathic pain", "dothiepin 75mg methylcobalamin 1500mcg benefits for nerve pain", "how dothiepin 75mg with methylcobalamin 1500mcg works for depression", "dothiepin methylcobalamin combination uses and side effects in India", "methylcobalamin 1500mcg with dothiepin for neuropathic pain relief", "methylcobalamin 1500mcg dothiepin combo cost in India", "is dothiepin 75mg with methylcobalamin 1500mcg safe?", "how to take dothiepin and methylcobalamin combination", "side effects of dothiepin 75mg with methylcobalamin 1500mcg", "methylcobalamin 1500mcg dosage for nerve pain" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "682dbede277ac71b03621d6c", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Duloxetine 20 mg, Methylcobalamin 750mg", "description": "DULOXTIME M 20/750 is a powerful combination medication used primarily in the management of neuropathic pain, fibromyalgia, diabetic nerve pain, and certain mood-related conditions. With a dual-action formula combining Duloxetine and Methylcobalamin, this medicine helps in managing nerve-related discomfort while also supporting nerve regeneration and mental well-being. It is often prescribed in chronic conditions where nerve pain and vitamin B12 deficiency coexist.\n\nKey Ingredients\nDuloxetine 20mg\nDuloxetine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that works on the central nervous system to relieve pain and improve mood. It is widely used for treating anxiety, depression, and chronic pain syndromes, especially those linked to nerve damage.\n\nMethylcobalamin 750mcg\nMethylcobalamin is an active form of Vitamin B12, essential for nerve health and red blood cell formation. It plays a vital role in regenerating damaged nerves and reducing symptoms like tingling, numbness, and weakness in patients with neuropathy.\n\nKey Benefits\nProvides effective relief from neuropathic pain and nerve inflammation\n\nEnhances nerve regeneration and improves nerve function\n\nSupports mental well-being by treating mood disorders like depression and anxiety\n\nCorrects Vitamin B12 deficiency, which is common in patients with nerve-related issues\n\nHelps manage chronic conditions like diabetic neuropathy and fibromyalgia\n\nMay improve sleep quality and reduce fatigue associated with nerve pain\n\nHow Does It Work?\nDuloxetine functions by increasing the levels of serotonin and norepinephrine in the brain. These neurotransmitters play a key role in pain modulation and emotional stability. By restoring their balance, Duloxetine alleviates both physical pain and associated psychological symptoms.\n\nMethylcobalamin, on the other hand, repairs damaged neurons and supports the formation of the protective myelin sheath around nerves. It contributes to the regeneration of nerve cells and improves nerve signal transmission, leading to a significant reduction in nerve pain and discomfort.\n\nTogether, these two components provide a synergistic effect, addressing both the root cause and the symptoms of neuropathic disorders.\n\nDirections for Use\nTake DULOXTIME M 20/750 exactly as prescribed by your doctor\n\nUsually taken once or twice daily with or without food\n\nSwallow the tablet whole with a glass of water; do not crush or chew\n\nConsistency is important — take the medicine at the same time every day\n\nDo not abruptly stop taking the medication without medical advice, as it may cause withdrawal symptoms\n\nSide Effects\nLike all medicines, DULOXTIME M 20/750 may cause some side effects. These are usually mild and temporary, but medical attention may be required if they persist.\n\nNausea or vomiting\n\nDry mouth\n\nDrowsiness or fatigue\n\nDizziness or light-headedness\n\nIncreased sweating\n\nConstipation\n\nLoss of appetite\n\nHeadache\n\nInsomnia (trouble sleeping)\n\nBlurred vision\n\nWeight changes\n\nMood swings or irritability (in rare cases)\n\nAllergic reactions like rash or itching (in very rare cases)\n\nIf you experience symptoms like severe dizziness, shortness of breath, persistent vomiting, or swelling, seek immediate medical help.", "price": 125.0, "discountamount": 38.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": [ "medicines duloxtime", "medicine helps", "medical attention", "medical advice", "swelling seek", "experience symptoms", "rare cases", "persist nausea", "side effects", "chew consistency", "food swallow", "components provide", "significant reduction", "emotional stability", "neurotransmitters play", "reduce fatigue", "effective relief", "tingling numbness", "reducing symptoms", "vital role", "active form", "mental wellbeing", "moodrelated conditions", "physical pain", "pain modulation", "relieve pain", "nerve cells", "nerve health", "nerve pain", "mood swings", "fatigue dizziness", "key role", "diabetic neuropathy", "chronic conditions", "neuropathic pain", "improve mood", "psychological symptoms methylcobalamin", "supporting nerve regeneration", "chronic pain syndromes", "neuropathy key benefits", "regenerating damaged nerves", "treating anxiety depression", "managing nerverelated discomfort", "powerful combination medication", "treating mood disorders", "severe dizziness shortness", "neuropathic disorders directions", "improve sleep quality", "breath persistent vomiting", "abruptly stop taking", "synergistic effect addressing", "protective myelin sheath", "balance duloxetine alleviates", "work duloxetine functions", "vitamin b12 essential", "central nervous system" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2124, "imageuri": "https://productimages.withfloats.com/actual/682dbee0ba49d0ed2a7bafaa.png", "tileimageuri": "https://productimages.withfloats.com/tile/682dbee0ba49d0ed2a7bafaa.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-05-21T11:54:06.394Z", "updatedon": "2026-03-13T07:37:01.425Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//duloxetine-20-mg-methylcobalamin-750mg/2124", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "DULOXTIME M 20/750", "category": "NEUROLOGY RANGE", "tags": [ "Duloxetine Methylcobalamin brand name", "Duloxetine hydrochloride Tablets Uses in Hindi", "Duloxetine and Methylcobalamin Tablets Uses in Hindi" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "666c09b805b00e1ad41ca790", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Topiramate 50mg", "description": "TP MATE 50 \nTopiramate (50mg)\nIntroduction:\nTP MATE 50 contains Topiramate, a versatile anticonvulsant and migraine prophylactic medication. With a dosage strength of 50mg, TP MATE 50 is designed to manage seizures in epilepsy and prevent migraines, significantly enhancing the quality of life for patients.\nKey Features and Benefits:\nAnticonvulsant Action:\nTP MATE 50 is highly effective in treating various types of seizures, including partial-onset seizures, generalized tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome. It stabilizes neuronal activity by enhancing GABAergic transmission, blocking sodium channels, and inhibiting glutamate activity.\nMigraine Prophylaxis:\n\nTopiramate is widely used for preventing migraines. By modulating neurotransmitter activity, TP MATE 50 reduces the frequency and severity of migraine attacks, helping patients manage their condition and improve their daily functioning.\nWeight Management:\n\nAn added benefit of TP MATE 50 is its potential to assist with weight loss. Unlike many anticonvulsants, Topiramate may lead to weight reduction, which can be beneficial for patients concerned about weight gain associated with other medications.\nMood Stabilization:\n\nTopiramate has mood-stabilizing properties, making it useful for patients with coexisting mood disorders such as bipolar disorder. It helps in stabilizing mood swings and reducing symptoms of anxiety and depression.\nWell-Tolerated and Safe:\n\nTP MATE 50 is generally well-tolerated with a favorable safety profile, making it a reliable option for long-term management of epilepsy and migraines.\nDosage and Administration:\n\nInitial Dosage for Epilepsy:\n\nThe initial dose of TP MATE 50 for adults with epilepsy typically starts at a low dose, gradually increasing to reduce the risk of side effects. A common starting dose is 25-50mg per day, increasing weekly by 25-50mg until the effective dose is reached. The usual maintenance dose ranges from 200-400mg per day, divided into two doses.\nInitial Dosage for Migraine Prophylaxis:\n\nFor migraine prevention, the initial dose is 25mg taken once daily, usually at night. The dose may be increased weekly by 25mg, up to a recommended dose of 50-100mg per day, divided into two doses.\nAdministration Instructions:\n\nTP MATE 50 tablets should be taken orally with or without food. It is important to maintain consistent dosing schedules to ensure stable therapeutic levels.\nContinued Monitoring:\n\nRegular monitoring of seizure frequency, migraine attacks, and potential side effects is essential during TP MATE 50 therapy to ensure therapeutic efficacy and patient safety.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order NOW \n", "price": 92.0, "discountamount": 28.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "day", "life", "food", "50mg", "25mg", "risk", "EMAIL", "night", "option", "adults", "anxiety", "quality", "symptoms", "severity", "50-100mg", "low dose", "epilepsy", "patients", "Benefits", "200-400mg", "two doses", "condition", "migraines", "Topiramate", "depression", "mood swings", "weight gain", "weight loss", "information", "Key Features", "sterispharma", "Introduction", "initial dose", "sterisonline", "CALL/WHATSAPP", "added benefit", "various types", "mood disorders", "patient safety", "Initial Dosage", "effective dose", "sodium channels", "dosage strength", "migraine attacks", "bipolar disorder", "weight reduction", "neuronal activity", "seizure frequency", "daily functioning", "other medications", "Weight Management", "Regular monitoring", "Mood Stabilization", "TP MATE 50 therapy", "glutamate activity", "TP MATE 50 tablets", "migraine prevention", "long-term management", "Migraine Prophylaxis", "Continued Monitoring", "common starting dose", "many anticonvulsants", "therapeutic efficacy", "Anticonvulsant Action", "usual maintenance dose", "potential side effects", "partial-onset seizures", "GABAergic transmission", "Lennox-Gastaut syndrome", "favorable safety profile", "versatile anticonvulsant", "neurotransmitter activity", "stable therapeutic levels", "Administration Instructions", "mood-stabilizing properties", "consistent dosing schedules", "migraine prophylactic medication", "generalized tonic-clonic seizures" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1905, "imageuri": "https://productimages.withfloats.com/actual/666c09bbf068be46bdec8995.png", "tileimageuri": "https://productimages.withfloats.com/tile/666c09bbf068be46bdec8995.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-14T09:13:28.046Z", "updatedon": "2026-03-12T11:58:29.217Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//topiramate-50mg/1905", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "TP MATE 50 ", "category": "NEUROLOGY RANGE", "tags": [ "TP MATE 50", "", "Topiramate (50mg)", "topiramate uses", "topiramate 50 mg", "topiramate side effects", "topiramate side effects weight loss" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "666c08e7c91739182c9574b6", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "TP MATE 100 ", "description": "TP MATE 100 \nTopiramate (100mg)\nIntroduction:\n\nTP MATE 100 contains Topiramate, a broad-spectrum anticonvulsant and migraine prophylactic medication. With a dosage strength of 100mg, TP MATE 100 is designed to manage seizures in epilepsy and prevent migraines, significantly enhancing the quality of life for patients.\nKey Features and Benefits:\n\nAnticonvulsant Action:\n\nTP MATE 100 is highly effective in treating various types of seizures, including partial-onset seizures, generalized tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome. It stabilizes neuronal activity by enhancing GABAergic transmission, blocking sodium channels, and inhibiting glutamate activity.\nMigraine Prophylaxis:\n\nTopiramate is widely used for preventing migraines. By modulating neurotransmitter activity, TP MATE 100 reduces the frequency and severity of migraine attacks, helping patients manage their condition and improve their daily functioning.\nWeight Management:\n\nAn added benefit of TP MATE 100 is its potential to assist with weight loss. Unlike many anticonvulsants, Topiramate may lead to weight reduction, which can be beneficial for patients concerned about weight gain associated with other medications.\nMood Stabilization:\n\nTopiramate has mood-stabilizing properties, making it useful for patients with coexisting mood disorders such as bipolar disorder. It helps in stabilizing mood swings and reducing symptoms of anxiety and depression.\nWell-Tolerated and Safe:\n\nTP MATE 100 is generally well-tolerated with a favorable safety profile, making it a reliable option for long-term management of epilepsy and migraines.\nDosage and Administration:\n\nInitial Dosage for Epilepsy:\n\nThe initial dose of TP MATE 100 for adults with epilepsy typically starts at a low dose, gradually increasing to reduce the risk of side effects. A common starting dose is 25-50mg per day, increasing weekly by 25-50mg until the effective dose is reached. The usual maintenance dose ranges from 200-400mg per day, divided into two doses.\nInitial Dosage for Migraine Prophylaxis:\n\nFor migraine prevention, the initial dose is 25mg taken once daily, usually at night. The dose may be increased weekly by 25mg, up to a recommended dose of 100mg per day, divided into two doses.\nAdministration Instructions:\n\nTP MATE 100 tablets should be taken orally with or without food. 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It is primarily prescribed to treat a variety of psychological disorders including depression, anxiety disorders, and obsessive-compulsive disorder (OCD). The controlled-release formula ensures a steady release of medication into the body, helping to maintain consistent blood levels throughout the day. This can lead to a reduction in side effects and an improvement in symptom management. Patients are advised to use this medication under the guidance of a healthcare provider, as it may have side effects such as nausea, drowsiness, and changes in appetite.\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order NOW\n \n", "price": 145.0, "discountamount": 44.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "day", "OCD", "SSRI", "body", "nausea", "variety", "changes", "12.5 mg", "guidance", "Patients", "appetite", "reduction", "Paroxetine", "drowsiness", "depression", "medication", "improvement", "side effects", "PAROXTIME CR", "steady release", "anxiety disorders", "symptom management", "healthcare provider", "consistent blood levels", "psychological disorders", "controlled-release tablet", "controlled-release formula", "obsessive-compulsive disorder", "selective serotonin reuptake inhibitor" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1146, "imageuri": "https://productimages.withfloats.com/actual/667d3350ce74849f89cdff37.png", "tileimageuri": "https://productimages.withfloats.com/tile/667d3350ce74849f89cdff37.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-05-07T06:12:58.668Z", "updatedon": "2026-03-13T06:39:28.025Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//paroxtime-cr-12-5-/1146", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Paroxetine 12.5 mg", "category": "NEUROLOGYRANGE", "tags": [ "Paroxetine 12.5 mg uses in hindi", "Paroxetine side effects", "Paroxetine 12.5 mg side effects", "paroxetine 12.5 mg+clonazepam 0.5 mg", "Paroxetine prolonged release tablets ip 12.5 mg", "paroxetine 12.5mg price in india", "Paroxetine 12.5mg price", "Paroxetine 20 mg uses" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false } ], "hasmoreitems": false, "isapirequest": false, "totalresults": 27, "query": null, "floatingpoint": null }